Publications

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active and passive immunization of chimpanzees infected with west african and southeast asian strains of plasmodium falciparum. 19664161626
testing of anti-human lymphocyte sera in chimpanzees and lower primates. 19684169065
description of a viral agent found in blood obtained from patients with infectious hepatitis.a small, double-stranded deoxyribonucleic acid viral agent (agent y) has been found in blood from patients with infectious hepatitis. the agent was propagated in chimpanzee liver tissue culture which had been grown and maintained on unheated agamma calf serum. a causal relationship between this agent and the occurrence of human disease cannot be determined from the data presented.19704191613
experimental syphilis in the chimpanzee. immunoglobulin class of early antibodies reactive with treponema pallidum. 19704193893
study of live typhoid vaccine in chimpanzees.streptomycin-dependent salmonella typhi containing o and h antigens was administered as a live oral antityphoid vaccine to chimpanzees. five animals served as controls; 5 others received the vaccine 4 times at 3-day intervals; 4 further animals were given 4 doses of vaccine at 3-day intervals together with streptomycin; and 1 animal received the 4 doses of vaccine and a daily dose of streptomycin. the individual vaccine doses varied between 36x10(9) and 82x10(9) organisms, totalling about 258x10 ...19704194259
development of antilymphocyte sera by cross immunization of chimpanzees and baboons. 19734198166
isolation of a new simian foamy virus from a spider monkey brain culture.a syncytium-forming (foamy) virus was isolated from a spider monkey brain cell culture. cytopathic effect was observed both in the brain culture and in human embryonic kidney cells. neutralizing antibody was present in the sera of the spider monkey from whom the isolation was made. the virus was inhibited by 5-bromo-2-deoxyuridine (20 mug/ml), contained a ribonucleic acid-dependent deoxyribonucleic acid polymerase, and had an infectivity peak at 1.15 g/cm(3) in a sucrose density gradient. the vi ...19734201323
blood group homologues in orangutans and gorillas of the human rh-hr and the chimpanzee c-e-f systems. 19734203423
studies on the sequential immunization against group b arboviruses in squirrel monkeys, cynomolgus monkeys, rhesus monkeys, and chimpanzees. 19744204022
characterization of a human acute phase protein found in association with rubella virus infection.a precipitating antigen, rho, was first detected in the blood of persons with rubella and in rubella virus-infected cell culture fluids (1). partially purified antigens from both sources were examined and shown to have similar properties, although antigen from serum sedimented more heterogeneously, with estimated coefficients from 15 to 21 s, while that from culture fluids sedimented in the 11-14 s region. in each case, antigen was located in the beta-1 zone after electrophoresis in agarose, and ...19744204728
[study on chimpanzees on the efficacy of an oral typhoid immunization with an inactivated antigen]. 19724205299
[studies on self-recognition in a mirror in orang-utans, chimpanzees, gibbons and various other monkey species]. 19734206430
proceedings: attempted infection of chimpanzees and cats with sarcocystis of cattle. 19744206530
[protein nutrition of the chimpanzee in its natural forest environment]. 19744219168
viral spectrum of an established chimpanzee liver cell line. 19664286950
histochemical localization of gastric and small bowel mucosal enzymes of man, monkey, and chimpanzee. 19674289803
the viral flora of the alimentary tract of chimpanzees. 19664291448
viruses of the alimentary tract of chimpanzees. 19674294618
experimental infections of chimpanzees with human rhinovirus types 14 and 43. 19684297694
monkeypox: experimental infection in chimpanzee (pan satyrus) and immunization with vaccinia virus. 19684298203
a subclinical outbreak of human rhinovirus 31 infection in chimpanzees. 19684299817
further studies of the viruses of the chimpanzee i. viral infection of colony-maintained chimpanzees. 19694311367
further studies of the viruses of the chimpanzee. ii. viral infection in recently imported chimpanzees captured in africa. 19694311368
comparison of antigens from human and chimpanzee herpes-type virus-infected hemic cell lines. 19704313153
host parasite relationships of chimpanzee viruses. arl-tr-69-9. 19694313204
viral flora of the gastrointestinal tract of newly imported juvenile chimpanzees. 19704317205
characterization of four new adenovirus serotypes isolated from chimpanzee tissue explants. 19714327999
presence of ebv antibodies in sera from wild chimpanzees. 19714329824
possible cytomegalovirus infection in man following chimpanzee bite. 19714331936
klebsiella-enterobacter infections in chimpanzees. 19714332173
antiviral activity of a bis-benzimidazole against experimental rhinovirus infections in chimpanzees.the marked antiviral activity of (s,s-1,2-bis(5-methoxy-2-benzimidazolyl)-1,2-ethanediol (abbott 36683) against rhinoviruses in tissue culture warranted investigation of its antiviral activity in vivo. antiviral levels in mouse sera were attained with an oral dose as small as 10 mg/kg and detectable antiviral levels of drug were also found in lung, liver, kidney, intestinal contents, and urine of mice given a single 300 mg/kg oral dose. antiviral serum levels were also obtained when monkeys were ...19724333893
further studies of the viruses of the chimpanzee. 3. infection and excretion patterns in imported chimpanzees. 19714336179
isolation and properties of the causal agent of a new variola-like disease (monkeypox) in man.the causal agent of a case of disease in man occurring in the democratic republic of the congo with a similar clinical picture to smallpox was isolated and studied. the agent was identified as monkeypox virus. a comparative study of the isolated strain (congo-8) and of viruses isolated from similar cases of illness in liberia (liberia-1 and liberia-2 strains) and sierra leone (v-70 1 266 strain) showed that they were identical. a number of local species of monkeys and apes were examined serologi ...19724340219
poxviruses isolated from clinically ill and asymptomatically infected monkeys and a chimpanzee.poxviruses were isolated from the kidneys of an outwardly healthy chimpanzee trapped in an area of the democratic republic of the congo where a case of monkeypox had recently occurred in man, from the kidneys of clinically healthy cynomolgus monkeys in a colony in the netherlands, and from monkeys suffering from monkeypox during outbreaks in colonies in the usa. it was established that two of the three viruses isolated from animals asymptomatically infected-namely, strain chimp-9 from the chimpa ...19724340220
lipid changes in the plasma lipoproteins of baboons given an atherogenic diet. 3. a comparison between lipid changes in the plasma of the baboon and chimpanzee given atherogenic diets and those in human plasma lipoproteins of type ii hyperlipoproteinaemia. 19724344001
isolation and partial characterization of chimpanzee plasma high density lipoproteins and their apolipoproteins. 19744360777
dietary induced hyperbetalipoproteinemia in chimpanzees: comparison to the human hyperlipoproteinemia. 19744363124
chimpanzee (pan troglodytes) serum high density lipoproteins. isolation and properties of their two major apolipoproteins. 19744366372
erythroleukemia in two infant chimpanzees fed milk from cows naturally infected with the bovine c-type virus. 19744370000
inability to detect hepatitis b virus or specific antigens in transformed chimpanzee lymphocytes.transformed chimpanzee lymphocytes were examined to determine whether they would support the replication of hepatitis b virus. after 5 months, no hepatitis b virus, hepatitis b surface antigen, or antibody to hepatitis b surface antigen was detected.19744373398
virological and clinical observations on chimpanzees exposed to tahyna virus aerosol. 19684386642
red cell enzyme polymorphisms in rhesus monkeys and chimpanzees. 19724400987
[muscles of the external ear and their function in man, chimpanzees and macaca]. 19744410191
ionic effects on the motility of bull and chimpanzee spermatozoa. 19744413987
the concentration of microfilariae of a guatemalan strain of onchocerca volvulus in skin snips taken from chimpanzees over 24 hours. 19744418413
hepatitis b core antigen: immunology and electron microscopy.two distinct viral antigens are associated with the hepatitis b virus: the hepatitis b surface antigen (hb(s)ag, australia antigen) and the hepatitis b core antigen (hb(c)ag). hb(s)ag, purified from the serum of asymptomatic human hb(s)ag carriers, and hb(c)ag, purified from the liver of a chimpanzee acutely infected with hepatitis b virus, were examined by serological and immune electron microscopic methods. antisera raised against hb(s)ag reacted with the outer, surface component of the dane p ...19744431086
urinary chorionic gonadotrophin excretion during pregnancy in the chimpanzee. 19744444016
dental arch growth in the gorilla, chimpanzee and orang-utan. 19724506976
dog homologue of human 2 -microglobulin.the amino-acid sequence of human beta(2)-microglobulin, a protein of 100 residues, is related to parts of the constant region of igg heavy chain. the dog homologue of human beta(2)-microglobulin has now been isolated and its amino-acid sequence has been partially determined. the two proteins (human and dog beta(2)-microglobulins) are demonstrably different at only 6 or 7 of the 42 positions examined. use of the dog should permit experimental investigation of the functional relationships of beta( ...19724507614
[karyotypic evolution in man and chimpanzees. a comparative study of band topographies after controlled denaturation]. 19724537726
[chromosomal phylogeny of man and the anthropomorphic primates. (pan troglodytes, gorilla gorilla, pongo pygmaeus). attempt at reconstitution of the karyotype of the common ancestor]. 19724539481
reactivity of treponemal and nontreponemal tests with cerebrospinal fluid from syphilitic chimpanzees. 19724550418
treponeme-like forms in chimpanzee aqueous humor and cerebrospinal fluid. 19724552455
[geotrichum and yeasts of the chimpanzee oral cavity. pan troglodytes (l.)]. 19724561876
transmission of type b viral hepatitis to chimpanzees. 19734574998
[analysis of the structure of chromatids of gorilla gorilla. comparison with homo sapiens and pan troglodytes (author's transl)]. 19734588466
treponemal igg and igm response in experimentally infected chimpanzees. 19744608796
viral hepatitis and studies of hepatitis associated antigen in chimpanzees. 19724622694
[karyotypes of man and the chimpanzee. comparison of the topography of bands. possible evolutive mechanisms]. 19724624970
immunological reactions in chimpanzees experimentally infected with schistosoma japonicum. 19724626877
gonorrhoea in the chimpanzee. infection with laboratory-passed gonococci and by natural transmission. 19724627047
running on two or on four legs: which consumes more energy?disagreement exists over whether man's bipedal form of locomotion evolved as an economical means for covering long distances. there is also some disagreement about the energetic price man had to pay to free his hands. in an investigation of the relative energetic cost of bipedal and quadrupedal locomotion in primates, chimpanzees (pan troglodytes) and capuchin monkeys (cebus capucinus) were trained to run on a treadmill either on two or on four legs while their oxygen consumption was being measu ...19734629856
chimpanzee urethral meningococci. 19734632813
infectious patterns of australia antigenemia and antibodies in chimpanzees. 19724633981
the behavior of chimpanzees in their natural habitat. 19734682742
age determination by immunological techniques of the last common ancestor of man and chimpanzee. 19734701781
pyrazinoate excretion in the chimpanzee. relation to urate disposition and the actions of uricosuric drugs.these experiments were designed to define the renal disposition of pyrazinoic acid in a nonhuman primate that is phylogenetically close to man and to relate this to the effects of pyrazinoate on urate excretion. the renal clearance of pyrazinoate was almost always greater than the simultaneous glomerular filtration rate at plasma concentrations ranging from 1.9 to 960 mug/ml. some inhibitors of tubular secretion, probenecid, mk-282 (an experimental, potent uricosuric drug), p-aminohippurate, iod ...19734719671
satellite sequences in chimpanzee (pan troglodytes). 19734748354
[use of boundary lines in the search for neurocranial sexual differences in man and chimpanzees]. 19734771742
new observations on the human and chimpanzee karyotypes. identification of breakage points of pericentric inversions. 19734785161
group response to the accidental death of a chimpanzee in gombe national park, tanzania. 19734789109
cross-reactivity of primate alloantigens: absorption of anti-hl-a reactivity from human alloantisera by chimpanzee lymphocytes. 19734797783
an outbreak of chimpanzee associated hepatitis. 19744836166
neisseria gonorrhoeae: effects of systemic immunization on resistance of chimpanzees to urethral infection. 19744842337
beta-glucuronidase response of cells infected with adenovirus types 5 and 12.beta-glucuronidase activity was investigated during a 48-h period in which virus replication and changes in cell morphology occurred. infection of an established line of chimpanzee liver cells with either nononcogenic adenovirus 5 or highly oncogenic adenovirus 12 under one-step growth conditions produced differing patterns of enzyme activity. there was an increase in total activity and also enhanced leakage of beta-glucuronidase from cells infected with adenovirus 12. in contrast, the enzymatic ...19744842701
localization of rdna in the chimpanzee (pan troglodytes) chromosome complement. 19744859400
defined leukocyte antigens of chimpanzees: use of chimpanzee isoantisera for leukocyte typing in man. 19674860686
studies on infection and immunity in experimental typhoid fever. 8. intravenous and intra-lymph node challenge of chimpanzees with salmonella typhi. 19684880691
experiments on the chemoprophylaxis of onchocerca volvulus infection.previous work on monkeys and on human volunteers led to the development of a schedule of diethylcarbamazine dosage suitable for the chemoprophylaxis of loiasis. in several parts of africa where this chemoprophylaxis is practised against loa loa, infections with onchocerca volvulus are also common. attempts were therefore made to determine whether diethylcarbamazine has any prophylactic action against the latter parasite by making use of chimpanzees exposed to experimental infections, and also by ...19684881070
mass diagnostic test using plasmodium falciparum and chimpanzee erythrocyte lysate. 19684882202
peripheral nerve grafts: experimental studies in the dog and chimpanzee to define homograft limitations. 19704904414
automated, quantitative microhemagglutination assay for treponema pallidum antibodies.an automated, quantitative microhemagglutination assay for antibodies to treponema pallidum was developed by using t. pallidum-sensitized erythrocytes and an automatic serial-dilution instrument. reactivity was found in sera from 54 rabbits and 6 chimpanzees infected with t. pallidum. reactivity was also found in sera from animals infected with t. pertenue, t. carateum, and t. cuniculi. no reactivity was found in sera from 75 normal rabbits or from 129 rabbits immunized with cultivatable trepone ...19694907009
induced double infection with plasmodium vivax and p. falciparum in a splenectomized chimpanzee. 19704909859
experimental infection with schistosoma haematobium in chimpanzees. 19704911014
tissue antigens of man and chimpanzees; their role in xenografting. 19704939693
transplantations of kidneys from chimpanzees to man. 19694950700
structural features of hypothalamus in man and other primates (chimpanzee, macaque). 19664956672
drug resistant plasmodium falciparum in the chimpanzee. 19664957842
individual differences in chimpanzee blood, demonstrable with absorbed human anti-rh0 sera. 19664961312
[experimental infections with schistosoma haematobium in mangabeys and chimpanzees]. 19674965613
[separation of the euryon and of the parietal prominence and transversal enlargement of the skull as a function of the position of this prominence in the human and the chimpanzee]. 19674967601
fluorescent antibody and gel diffusion reactions of human and chimpanzee sera with cells cultured from burkitt tumors and normal chimpanzee blood. 19684973344
afferents and efferents at the level of somatomotor cortex in awake monkeys: comparison with results obtained in chimpanzee. 19694976349
discussion paper: isoprecipitins to alpha 2-macroglobulins in chimpanzees. 19694979544
chimpanzees: self-recognition.after prolonged exposure to their reflected images in mirrors, chimpanzees marked with red dye showed evidence of being able to recognize their own reflections. monkeys did not appear to have this capacity.19704982211
a molecular time scale for human evolution.we discuss published molecular evidence concerning the relationship of man to african apes and old world monkeys. quantitative comparisons of their serum albumins, transferrins, hemoglobins, and dna show that man is genetically much more similar to the african apes than to the old world monkeys. the amino acid sequences of hemoglobins from humans, chimpanzees, gorillas, and rhesus monkeys are consistent with the hypothesis that the probability of an amino acid substitution occurring in a given i ...19694982244
on the proportions between some areas of the first cervical segment of the spinal cord of primates.it has been generally supposed that the dorsal funiculi occupy a relatively larger part of the highest segments of the spinal cord in man than in any other primate. we have taken planimetric measurements of the total area of the cord, dorsal funiculi, and total gray in the uppermost segments of the spinal cord of a wide variety of primates. our results indicate that the largest values for the proportions dorsal funiculi/total white matter and dorsal funiculi/ventrolateral funiculi are found in g ...19694982246
isolation and characterization of alpha 1-acid glycoprotein from chimpanzee plasma. 19704984628
histopathological lesions of rhesus monkeys and chimpanzees infected with schistosoma japonicum. 19694986176
comparison of the lymphocyte transformation test with the tuberculin test in rhesus monkeys and chimpanzees. 19704988805
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