| interference of 4-amino-4-deoxy-n10-methylpteroic acid with the radioimmunoassay of methotrexate. | | 1979 | 262195 |
| variation in conduction velocity during the relative refractory and supernormal periods: a mechanism for impulse entrainment in central axons. | | 1979 | 262231 |
| trigeminal nerve and temporomandibular joint of the cat: a horseradish peroxidase study. | | 1979 | 262237 |
| changes in rat lung produced by olivine dust inhalation. | | 1979 | 262291 |
| biologic properties of lyophilized live typhoid vaccine strains. | | 1979 | 262514 |
| attempts to immunize rats against infection with fasciola hepatica using in vitro culture antigens from newly excysted metacercariae. | attempts were made to immunise rats against fasciola hepatica using the culture products obtained from the in vitro cultivation of newly excysted metacercariae. three culture regimes were chosen: (1) medium nctc 135 for 48 h (2) nctc 135 + 20 per cent fetal calf serum (fcs) for 48 h (3) nctc 135 + 20 per cent fcs for 14 days. the used culture medium from each of these regimes was concentrated, mixed with adjuvant and injected subcutaneously into rats. similarly treated unused culture media was u ... | 1979 | 262614 |
| [the morphodynamics of the adrenal cortex in gravid rats (author's transl)]. | | 1979 | 262723 |
| [phage types of vibrio cholerae and non agglutinable vibrio isolated in algeria from 1975 to 1977]. | 1 285 strains of vibrio cholerae and 556 strains of non agglutinable vibrio were isolated either from stool specimens or water in algeria from 1975 to 1977. these strains were phage-typed with basu and mukerjee's 5 phages for the vibrio biotype el tor and with mukerjee's phage iv for the vibrio biotype cholerae. the results obtained are discussed in terms of choleraphages used for the diagnosis and epidemiological study of cholera. | 1978 | 262967 |
| [some aspects of the evolution of cholera in algeria from 1971 to 1975]. | taking as a basis information collected in their laboratory, the authors study certain aspects of the evolution of cholera in algeria during the different outbreaks from 1971 to 1975. 6 301 strains of vibrio-cholerae (mainly serotype ogawa) were isolated either from cholera patients or carriers. all but two of strains were sensitive to all antibiotics tested. most of the wilayate (districts) were affected during these outbreaks which took place from june to december; the majority of cases were o ... | 1978 | 262968 |
| on the psychology of the aging woman. depression in late mid-life: change or repetition? another chance for working through. | a woman of 58 came for psychotherapy for the first time suffering from a depressive reaction precipitated by two mid-life events: the marriage of her daughter and the realization that her own cherished marital dream would never be fulfilled. she had postponed coming to terms with the disappointments of her marriage as long as she had had other objects. when these objects were lost, and the distance she had maintained to handle her feelings was threatened, she sought help. there was suggestive ev ... | 1979 | 263175 |
| can you spot the games patients play to get pills to pop? | | 1979 | 263247 |
| adenylate cyclase of human parathyroid gland. | experiments were performed on a particulate fraction from human parathyroid glands. a high activity of adenylate cyclase was detected which was linear with time and protein concentration. the enzyme had an optimum ph in the range of 7-8 and a km for atp of 0.44 x 10(-3) m. ca++ had a profound inhibitory effect; a concentration of 0.5 mm ca++ reduced enzyme activity by 60%. maximal enzyme activity was obtained with 5 mm mg++; higher concentrations of this cation also inhibited enzyme activity. th ... | 1978 | 263299 |
| fetal hypothyroidism and maternal thyroid status in severe endemic goiter. | the relationship between maternal thyroid function and newborn thyroid function was studied in a region of very severe endemic goiter (ubangi, republic of zaïre). t4, t3, and tsh concentrations were measured in the sera of 56 mothers (at the time of delivery) and 60 newborns (in the cord). the results obtained in these groups (untreated) were compared with those obtained in two control groups, comprising 53 mothers whose iodine deficiency had been corrected by the injection of iodized oil and 68 ... | 1978 | 263304 |
| heterogeneity of pituitary and plasma prolactin in man: decreased affinity of "big" prolactin in a radioreceptor assay and evidence for its secretion. | | 1978 | 263349 |
| [indicators of protein metabolism in infants with intrauterine dystrophy red various dietary mixtures]. | in the previous work published in no 7 of "development period medicine" ( problemy medycyny wieku rozwojowego ) the results of nitrogen balance studies in s-f-d infants fed different milk formulas were described. the present study concerns other protein metabolism indices in the same infants. the infants were divided into four groups according to the formula they were fed. the composition of formulas is shown in table i. in the infants besides the balance study, serum urea nitrogen, protein and ... | 1979 | 263533 |
| closure of the human umbilical artery: a physiological demonstration of burton's theory. | 30 umbilical cords of normal full-term infants were examined immediately after birth for closure of the arteries. multiple constrictions were observed in the arteries at birth, which increased in number and degree with time. between the constrictions there were segments of dilatations with trapped blood. cutting through the constrictions in the cords clamped later than 1 min after birth did not result in leakage of blood from the adjoining dilated segments which contained trapped uncoagulated bl ... | 1977 | 264063 |
| epidemiological analysis of factors influencing rate of progress in echinococcus granulosus control in new zealand. | the factors influencing the rate of progress in echinococcus granulosus control in new zealand were analysed by hydatid control area using stepwise multiple regression techniques. the results indicated that the rate of progress was related positively to initial e. granulosus prevalence in dogs and the efficiency with which local authorities implemented national control policy, and negatively to the maori proportion in the local population and the number of dogs per owner. problems in analysis of ... | 1977 | 265340 |
| isopeptide linkage between nonhistone and histone 2a polypeptides of chromosomal conjugate-protein a24. | chromosomal protein a24 has a unique structure inasmuch as it contains histone 2a and a nonhistone polypeptide the sequence of which has been partially determined. comparative analysis of the ninhydrin-insensitive amino-terminal tryptic peptides of protein a24 and histone 2a and a quantitative analysis of their carboxyl-terminal amino acid indicated that protein a24 has two amino termini and one carboxyl terminus. the amino acid sequence analysis of tryptic peptide 17' of protein a24: (see text) ... | 1977 | 265581 |
| chromosome banding patterns of 49 cases of chronic myelocytic leukemia. | | 1977 | 266114 |
| thermotaxis by pseudoplasmodia of dictyostelium discoideum. | the temperature dependence of migration rate and of the thermotactic sensitivity of pseudoplasmodia of dictyostelium discoideum has been measured. migration rate increases with temperature to 20 degrees, is temperature insensitive from 20 degrees to 27.5 degrees, and decreases with temperature to 29 degrees, above which point migration ceases. however, pseudoplasmodia formed from cells grown at 23.5 degrees are thermotactic only from 22 degrees to 27.5 degrees. thus, a temperature dependence of ... | 1977 | 266720 |
| the representation of motor-unit action-potentials on skin-surface electromyograms of the masseter and temporal muscles in man. | | 1977 | 266875 |
| unwinding protein specific for mrna translation fractionated together with rabbit reticulocyte initiation factor 3 complex. | experiments with a rabbit reticulocyte cell-free system dependent on the addition of initiation factor 3 (eif-3) and mrna were carried out. in this system, using ribosomal subunits, aug(u)(n) can direct polyphenylalanine synthesis in the absence of eif-3 at 3 mm mgcl(2). globin mrna was not translated under similar conditions; its translation requires the addition of eif-3. moreover, the maximal rate of globin synthesis was achieved when the molar ratio of eif-3 to ribosomes was approximately 1. ... | 1977 | 267926 |
| role of perivascular sympathetic nerves in autoregulation of cerebral blood flow and in blood-brain barrier functions. | | 1977 | 268889 |
| an autoradiographic study of the sensory innervation of teeth. ii. dental pulp and periodontium. | autoradiography of axoplasmically transported proteins revealed that both dental pulp and periodontium receive sensory innervation from the trigeminal ganglion in the form of plexuses and free and organized sensory receptors, including apparent corpuscular ones. corpuscular receptors in the pulp suggest this tissue may be responsive to modalities other than pain. | 1977 | 269163 |
| ultrastructural localization of cell membrane gm1 ganglioside by cholera toxin. | an immunoelectron microscopic method is described for sensitive high-resolution visualization of tissuebound cholera toxin. the principle is to incubate cells or tissue sections with toxin and then to localize the bound toxin with toxin-specific peroxidase (donor:hydrogen-peroxide oxidoreductase; ec 1.11.1.7)-conjugated antibody and enzyme substrate. thin sections are examined for electron-opaque precipitates in a transmission electron microscope. because of the specific binding of the toxin to ... | 1977 | 269432 |
| loss of growth control and differentiation in the fu-1 variant of the l8 line of rat myoblasts. | a nonfusing variant, fu-1, of the l8 line of rat myoblasts was isolated and characterized with respect to its growth in vitro and developmental properties. comparative analyses of density-dependent inhibition of growth, serum requirements, cell adhesiveness, colony formation in soft agar, and hexose transport in l8 and fu-1 cells support the conclusion that the fu-1 cells are transformed. in addition, fu-1, but not l8, cells promote the development of tumors in athymic nude mice. fu-1 cells also ... | 1977 | 269441 |
| comparative cariogenicity of streptococcus mutans strains isolated from caries active and caries resistant adults. | | 1977 | 270487 |
| in vitro enamel demineralization by streptococcus mutans in the presence of salivary pellicles. | salivary pellicles developed on extracted teeth favorably affected the degree and nature of enamel demineralization when the teeth were incubated in vitro with either of two pure strains of cariogenic streptococcus mutans. the mechanism responsible for this protection may relate to the permselective properties of these salivary pellicles. | 1977 | 270509 |
| effect of galactose oxidase, with and without prior sialidase treatment, on the viability of erythrocytes in circulation. | previous studies have shown that sialidase-treated mammalian erythrocytes were rapidly eliminated from circulation. in contrast, chicken asialoerythrocytes remained fully viable. this investigation was undertaken to ascertain the reason for this difference in behavior as well as to determine the extent of the similarity of the physiological mechanism for the elimination from circulation of asialoglycoproteins and mammalian asialoerythrocytes. to that end, erythrocytes from dogs, rabbits, and chi ... | 1977 | 270664 |
| participation of providence senior citizens in the swine flu inoculation program. | | 1977 | 270786 |
| [kinetics of the enzymatic degradation of lymphocyte nuclei in cattle blood normally and in leukemia]. | | 1978 | 272398 |
| effect of dietary supplements of fluoride on development of dental caries in the rat. | | 1978 | 272955 |
| waardenburg-like features with cataracts, small head size, joint abnormalities, hypogonadism, and osteosarcoma. | a 32-year-old black man was observed with osteosarcoma and multiple anomalies including deafness, hypopigmentation, cataracts, small head size, hypogonadism, and restricted joint mobility. the birth defects may comprise a new syndrome or combination of syndromes, of which the malignancy may be a part. | 1978 | 273099 |
| susceptibility of bacteria isolated from oral infections to nine antibiotics in vitro. | | 1978 | 273312 |
| one case of a ph1 chromosome resulting from translocation of the distal end 22q onto the short arm of chromosome 15. | | 1978 | 275027 |
| modifications of lectin binding on human leukemic cells after neuraminidase treatment. | cell surface modifications after vibrio cholerae neuraminidase treatment were investigated using three different tritiated lectins: concanavalin a, ricinus sanguineus agglutinin (r.s.a.) and robinia pseudoacacia lectin. lectin binding measurements were performed on untreated and enzyme treated cells. the cells used were from chronic and acute leukemic donors. after neuraminidase treatment, a significant increase in the number of receptor sites, from 1 to 3 times, was found in all cases tested an ... | 1978 | 276384 |
| binding of atp to progesterone receptors: properties and functional significance of this interaction. | | 1977 | 281180 |
| hemolytic anemia. associated with severe mycoplasma pneumoniae pneumonia. | | 1978 | 281612 |
| neuraminidase alteration of human lymphocyte reactivity to mitogens, antigens and allogenic lymphocytes. | lymphocyte reactivity to phytohemagglutinin (pha) was reduced significantly in whole-blood cultures initiated with nontoxic concentrations of vibrio cholerae neuraminidase (vcn). reduced responsiveness was not due to degradation or inactivation of pha by this enzyme, and the reaction was dependent upon the dose and time at which this mitogen and enzyme were added to the cultures. in cultures from some subjects, vcn also inhibited reactivity to concanavalin a. in contrast, lymphocyte reactivity t ... | 1978 | 283169 |
| some prognostic and epidemiologic factors in canine osteosarcoma. | naturally occurring skeletal osteosarcomas in a series of 144 untreated dogs were found especially to involve the ends of the long bones of the forelimbs and affected predominantly older male dogs of giant and large breeds. most tumors were large and partially necrotic and had extended into soft tissues. of 12 host and tumor characteristics tested in the first part of the study, tumor diameter and volume were significantly associated with the presence of pulmonary metastases at autopsy. the seco ... | 1979 | 283283 |
| emergence of a cell line with extreme hypodiploidy in blast crisis of chronic myelocytic leukemia. | cytogenetic studies in a patient with chronic myelocytic leukemia (cml) demonstrated the emergence of an extremely hypodiploid cell line at the time of blast crisis, a modal chromosome number of 35, with the modal karyotype 35,xy, -3, -4, -5, -7, -9, -11, -12, -13, -15, -16, -17, -19, -20, -22, + t(9;22) (q34;q11, + mar1, + mar2, + mar3. giemsa-banding confirmed complex chromosome rearrangements and demonstrated distinct banding patterns for the marker chromosomes. cytologic characteristics of t ... | 1979 | 284783 |
| natural cytotoxicity of mouse, rat, and human lymphocytes against heterologous target cells. | natural cell-mediated cytotoxicity by a particular subpopulation of lymphocytes [designated natural killer (nk) cells] in nih swiss nude and cba/n mice, wf rats, and humans was demonstrated against tumor cells in 4-hour 51cr release assays. in most studies, only reactivity against target cells of the homologous species was examined. in the present studies, mouse nk activity also was found against a rat lymphoma tissue culture cell line and against human tissue culture lines. rat nk cells reacted ... | 1979 | 285291 |
| transposon-facilitated recombination in vibrio cholerae. | improved vibrio cholerae donors were constructed by introducing the ampicillin transposon, tn1, into both the conjugative plasmid, p, and the bacterial chromosome to provide "portable regions of homology." the resulting tfr (transposon-facilitated recombination) donors transferred genes at high frequency from origins specified by the chromosomally inserted tn1 copies. tn1 was transposed into the chromosome from a deleted p::tn1 vector, which was eliminated from the cells by superinfection with a ... | 1979 | 286148 |
| hybrid mammalian cells assemble hybrid ribosomes. | hybrid cell lines formed by fusion of mouse 3t3 cells and chinese hamster ovary (cho) cells resistant to emetine, which have an altered 40s ribosomal protein, are generally sensitive to emetine. from most hybrid lines it was possible to select sublines resistant to emetine. the ribosomal components of three lines were studied: a34, an emetine-sensitive hybrid; a34/r3, an emetine-resistant derivative of a34; and a72, an emetine-sensitive hybrid that did not give rise to emetine-resistant sublines ... | 1979 | 293661 |
| transplantation of organ cultured rat parathyroids. | the hypothesis that tissue culture alters the immunogenicity of grafts by removal or inactivation of passenger leucocytes has been investigated in an inbred rat parathyroid allograft model. da rat (ag-b4) parathyroid glands cultured for up to three weeks in eagle's minimal essential medium (mem) alone, or mem with added donor-specific antilymphocyte serum, did not survive longer than fresh glands when allografted into lewis rat (ag-b1) recipients. subsequent in vitro comparisons of three differe ... | 1979 | 294266 |
| biologic effects of endodontic antimicrobial agents. | | 1979 | 296259 |
| in vivo study of respiratory depression of pulp tissue resulting from cavity preparation and dental materials. | | 1979 | 298765 |
| absorption tests on cold lymphocytotoxins: preliminary report. | tests were carried out to absorb cold lymphocytotoxic antibodies on different types of cells. these included lymphocytes and neuraminidase-treated lymphocytes from healthy donors, thymocytes from children undergoing open heart surgery, fetal thymocytes, human brain and cultured lymphocytes. the results showed these antibodies to be absorbed on some types of cells and eluted from others. the best absorption was obtained with fetal thymocytes and brain tissue. | 1977 | 302062 |
| analysis of lymphocyte surface antigen expression by the use of variant cell lines. | | 1977 | 302193 |
| sensitivity of the vibrios to ultraviolet-radiation. | the ultraviolet-inactivation kinetics of a number of strains of vibrio cholerae (classical), vibrio cholerae (el tor), nag vibrios and vibrio parahaemolyticus were investigated. statistical analyses revealed significant differences between any two of the four types of vibrio in respect to their sensitivity to u.v. | 1977 | 302245 |
| immunosuppression in man: suppression by macrophages can be mediated by interactions with regulatory t cells. | | 1977 | 302274 |
| [incidence of infant tuberculosis in germany during the first year after cessation of unselected bcg vaccination (author's transl)]. | at the end of may 1975, bcg vaccine was withdrawn from the market in the federal republic of germany, because a newly introduced vaccine had given rise to untoward reactions. neonatal vaccination practically ceased. the results of a survey by questionnaire, undertaken on behalf of the vaccination committee of the german society for social paediatrics, are reported. from 1.9.1975 to 31.8.1976 the incidence of tuberculosis in the first year of life had already doubled compared with the reported an ... | 1977 | 302786 |
| cell-mediated immunity to tumor antigen in marek's disease: susceptibility of effector cells to antithymocyte serum and enhancement of cytotoxic activity by vibrio cholerae neuraminidase. | spleen cells from chickens inoculated 7 to 8 days previously with marek's disease virus were cytotoxic for 51cr-labeled cells of a marek's disease lymphoblastoid cell line (msb-1 line) in a 4-h in vitro cytotoxic assay. the cytotoxic activity of spleen cells was inhibited by pretreatment with antithymocyte serum and complement, but not with complement alone or in combination with anti-bursa cell serum or normal preimmune serum. the conclusion was that the effector cell in the above cytotoxic ass ... | 1977 | 302827 |
| human b lymphocytes in giemsa stained preparations. | a mixed antiglobulin procedure has been developed to provide simultaneous study of cell surface immunoglobulin and detailed cytological features in giemsa stained preparations. the percentage of surface immunoglobulin bearing lymphocytes, monocytes and granulocytes changed dramatically when lymphocytes were incubated at 37 degrees c, or following sheep erythrocyte rosette enrichment procedures. | 1977 | 302844 |
| natural cell-mediated immunity to lymphoma cells. i. characteristics of effector cells in a cytostasis assay in vitro. | spleen cells from normal, nonimmune, cba or (cba x akr)f1 mice markedly and rapidly inhibited the incorporation of [3h]thymidine by two different t-cell lymphomas in an in vitro cytostasis assay. these were the i-529 lymphoma of spontaneous akr origin and the moloney murine leukemia virus-induced yac lymphoma of a mouse origin. spleen cells were the most efficient inhibitors for both types of target cells, whereas lymph node cells were much less active and thymus cells showed little or no activi ... | 1977 | 302867 |
| [cellulitis and bacteremia caused by haemophilus influenza group b]. | | 1977 | 302886 |
| freezing of rat lymphocytes. iv. in vitro and in vivo responses of t-cells. | rat lymph node lymphocytes have been frozen-thawed with 10% dimethyl sulphoxide as cryoprotectant. the present study shows that these cells respond well in t-cell functional assays, such as stimulation with phytohaemagglutinin, as responder cells in the mixed lymphocyte reaction and in the local graft-versus-host assay. the magnitude of the responses obtained with frozen-thawed cells was some 70-80% of corresponding fresh cells. | 1977 | 303436 |
| ontogeny of myelopoietic precursor cells in the chicken embryo. | the agar culture technique which enables enumeration of myeloid precursor cells was used to establish the time of appearance and further development of these cells in chick embryos. yolk mesenchyme is the largest producer of precursor cells from day 6 to day 17 of incubation. in circulating blood precursor cells probably from the yolk appear at day 9 and stay at fairly high levels till day 17. spleen and bone marrow have high percentage of precursor cells from day 10 till hatching, but afterward ... | 1977 | 303449 |
| induction in b2/b2 chickens of immunity to transplantable carcinogen-induced fibrosarcomas mediated by t-cell monocyte cooperation: role of delayed hypersensitivity to unrelated antigens. | | 1977 | 303451 |
| neuraminidase- and trypsin-induced exposure to membrane receptors for igg and igm molecules on human peripheral blood lymphocytes. | brief incubation of human peripheral blood lymphocytes with vibrio cholerae neuraminidase (vcn) or trypsin revealed hidden membrane receptors for igg and igm molecules. the hidden receptors were found on t lymphocytes as shown by double-label and mixed rosetting experiments and by studies of t-enriched populations. although igm receptors were undetectable on freshly isolated lymphocytes, a mean of 17.1% of vcn-treated lymphocytes rosetted with ox erythrocytes coated with igm antibody (ea-igm). p ... | 1977 | 303965 |
| [histochemistry of lipids and carbohydrate in the rat skin. the sebaceous gland and its duct]. | | 1977 | 305621 |
| [pharmacologic properties of ortho-ethoxy-benzamide]. | | 1977 | 305744 |
| x-linked recessively inherited non-specific mental retardation. report of a large family. | a large kindred is described in which 22 males and 3 females show non-specific mental retardation with impaired speech. an x-linked recessive is the most likely mode of inheritance of this condition. similar families have been described in the literature, characteristic physical abnormalities are absent and performance i.q. tends to be higher than verbal i.q. this possible heterogenous condition may be a major individual cause of mental deficiency in males, and may account for the excess of male ... | 1977 | 305754 |
| partial duplication 5q syndrome: phenotypic similarity in two sisters with identical karyotype (partial duplication 5q33 leads to 5qter and partial deficiency 8p23 leads to pter). | two sisters with statomotor developmental retardation microcephaly, hydrocephalus internus and externus without signs of pressure, heart defect (ventricular septal defect), early pulmonary resistance and characteristic facial changes were found to have the same unbalanced karyotype with partial trisomy 5q3300 leads to 5qter and partial monosomy 8p2300 leads to 8pter, derived from a balanced reciprocal paternal translocation: 46,xy,t(5;8)(q3300;p2300). the older girl was tested for the erythrocyt ... | 1977 | 305758 |
| para-aminobenzoic acid. | | 1978 | 305886 |
| effect of doxycycline on transmission of vibrio cholerae infection among family contacts of cholera patients in calcutta. | doxycycline was used among the family contacts of hospitalized cholera patients in calcutta to determine its effectiveness in controlling transmission of v. cholerae infection. a total of 137 such contacts were given a single oral dose of doxycycline in graded doses according to age. a similar group of 139 contacts received a single dose of multivitamins as placebo. all 276 contacts were examined bacteriologically daily for 10 days for the presence of v. cholerae in their stools. the results sho ... | 1978 | 307459 |
| role for macrophages and thymus-derived lymphocytes in cholera toxin-induced immunosuppression. | the exo-enterotoxin derived from vibrio cholerae bacilli has marked immunomodulating activities, both in vivo and in vitro. in the present study, the mechanism whereby cholera toxin depresses the antibody-forming ability of murine splenocytes was investigated by in vitro reconstitution experiments. spleen cells derived from mice treated with cholera toxin 2 days earlier were markedly deficient in their ability to respond to sheep erythrocytes upon challenge immunization in vitro. addition of gra ... | 1978 | 307537 |
| immune function in patients with multiple myeloma (delayed cutaneous reactivity and lymphocytes bearing receptors for sheep, human and mouse erythrocytes). | immunologic function was evaluated in 27 patients with multiple myleoma (mm). when tested for their ability to develop delayed hypersensitivity to panel of skin test antigens, 2 out of 15 such patients were found to be anergic. the property of human peripheral blood t lymphocytes to form rosettes with sheep [total e and active or early rosette-formimg cells (rfc)] and human erythrocytes (h-rfc) was also studied. in addition, rosette formation with mouse erythrocytes (m-rfc) was investigated as a ... | 1977 | 307801 |
| interaction of vaccines with t and b lymphocytes and macrophages in the immune response system. | | 1978 | 308311 |
| [cortical tissue from syngenous brain as a stimulator of immunogenesis in thymectomized mice]. | experiments on cba mice showed that the gray matter homogenate of the syngeneic brain contained components reconstituting the t-cell population in the spleen of thymectomized animals and possessing a stimulating effect on the immune response to sheep red blood cells. the white matter homogenate was much less active, it is not excluded that the trace activity is due to the gray matter admixture in the preparation. syngeneic muscle tissue homogenate possessed no biological activity. | 1978 | 308821 |
| the renal pelvis and selected measurements of the cat kidney. | | 1978 | 308900 |
| genetic control of the content and avidity of hapten-binding b lymphocytes in mouse spleen. | | 1978 | 308926 |
| demonstration of antinuclear antibodies in mercuric chloride-induced glomerulopathy in the rat. | serial administration of mercuric chloride to pvg/c rats induced a glomerulopathy associated with immune complex deposition along the glomerular basement membrane and in the mesangial area. these deposits could be demonstrated by immunofluorescence and electron microscopy 5 to 8 weeks after the first injection of mercuric chloride. at this time antinuclear antibodies could be demonstrated in the sera and in the eluates from the renal cortices from diseased animals. these findings suggest a possi ... | 1978 | 309027 |
| apparatus for uniaxial testing of soft human tissues in vitro. | | 1978 | 309051 |
| t cell regulation of specific b cell responses. | | 1978 | 309894 |
| preparation and laboratory testing of plain and aluminum hydroxide-adsorbed cholera vaccines used in a field trial in indonesia. | two types of cholera vaccine were prepared: a plain vaccine and an aluminium hydroxide-adsorbed vaccine, by using the inaba nih 35a3 and ogawa nih 41 serotypes of vibrio cholerae. for cultivation, a solid medium was used and the cultures were inactivated with 0.02% thiomersal and by heating for 1 hour at 56 degrees c. the final vibrio concentration of the vaccines was adjusted to 16 x 10(9) vibrios/ml (equal proportions of the two serotypes). the antigenicity of the vaccines was assessed by the ... | 1978 | 310362 |
| human mammary carcinoma cells. the enzyme pacemaker profibrinolysin. | when cultured in-vitro, originating from different breast cancer patients, tumor cells, identified histologically as carcinoma cells, varied in their proliferation patterns and cell morphology. if exposed for brief periods to vibrio cholera neuraminidaes (vcn), the amount of sialic acid released from the cells varied from one culture to another and increased with higher enzyme concentrations. if exposed to trypsin, the amount of released proteins varied also from one culture to another. signific ... | 1978 | 311626 |
| adherence of wild-type and mutant strains of vibrio cholerae to normal and immune intestinal tissue. | adherence of some wild-type and mutant strains of vibrio cholerae was studied and the relation between adherence, motility, multiplication, and virulence was examined. vibrios adhered readily to freshly isolated tissue segments of rabbit intestine at 37 degrees c. the number of vibrios adhering was dependent on the concentration of bacteria to which the tissue was exposed. adherence was markedly reduced by pretreatment with chloramphenicol and also when intestinal tissue was taken from parentera ... | 1979 | 311709 |
| r plasmids in vibrionaceae - beta-lactamases in vibrio cholerae (nag-heiberg ii) and a. hydrophyla. | 290 natural isolates of aeromonas, plesiomonas and vibrio strains isolated from surface waters have been tested for antibiotic resistance, and 123 have been found resistant to various drugs, mostly beta-lactam antibiotics. 14 of them, with high-level of resistances, transfered antibiotic resistance using three recipient strains of enterobacteriaceae. one strain of vibrio nag (heiberg ii) transfered the resistance to ampicillin, carbenicillin and cephaloridin to both e. coli k12 3110 and s. typhi ... | 1978 | 311984 |
| separation of human t lymphocyte subpopulations (tmu, tgamma) by density gradient electrophoresis. | purified human peripheral blood t lymphocytes were fractionated by density gradient electrophoresis on the basis of their surface charge. the high mobility cell fractions were found to be enriched in t cells having receptors for igm (tmu cells) with only minor proportions of t cells having receptors for igg (tgamma cells). in contrast, the low mobility cell fractions were enriched in tgamma cells with very low numbers of contaminating tmu cells. both populations were of higher mobility than huma ... | 1979 | 313051 |
| [the pathophysiology of tourniquet shock]. | in rabbits a tourniquet shock was produced by 4-hour unilateral ischemia of one hind leg. by measuring the tissue oxygen tension on the surface of the ischemically damaged muscle, the liver and kidney the regional rate of perfusion of these organs in the state of shock was investigated. additionally morphological examinations of muscle, liver, kidney and heart were carried out. in therapeutic trials with a proteinase inhibitor (trasylol), prednisolone and streptokinase, trasylol proved to prolon ... | 1979 | 313360 |
| quantification of bcg-induced reactions of t and b areas in peripheral lymphoid organs of young adult balb/c mice. a histomorphometrical and autoradiographical study. | significant structural alterations of the axillary lymph nodes and spleens were revealed by histomorphometry following intraperitoneal injection of bcg into young adult balb/c mice. the relative proportions of the germinal center areas were increased in lymph nodes as well as in spleens. the overall proportion of the b cell areas, however, showed a significant increase only in the spleens, compared to a significant reduction in the lymph nodes. by contrast, t cell areas appeared significantly re ... | 1979 | 313564 |
| angioimmunoblastic lymphadenopathy evolution to a burkitt-like lymphoma. | | 1979 | 313708 |
| developmental transformations of fetal kidney in pig and sheep. | | 1979 | 315353 |
| attenuation of virulence by p and v plasmids in vibrio cholerae: strains suitable for oral immunization. | in a virulent strain of vibrio cholerae, kb9, p and v plasmids were introduced by bacterial conjugation. characterization of pv isolates and systematic screening of them in animal models of cholera revealed that a large number of pv isolates were non-pathogenic, owing to the loss of ability to synthesize toxin. results obtained with two such strains, designated as kb9:pv and cd24, are described. the strains with plasmids were stable during in vitro cultivation or during two successive passages i ... | 1979 | 316741 |
| attenuated recombinant strains of vibrio cholerae for oral immunization. | two attenuated strains of vibrio cholerae, cd1 and cd3, have been isolated that have remained stable since 1976. these strains are motile, adhere to and multiply in rabbit intestine, and colonize the gut of infant mice for 6-7 days. both strains are antigenic and provide protection to challenge in the mouse protection test and in the rabbit ileal loop model. because of their ability to adhere to and colonize the gut, and since they are antigenic, strains cd1 and cd3 have the potentiality of oral ... | 1979 | 316742 |
| the lipid content of epididymal spermatozoa of rattus norvegicus. | 1. seven major lipids of rat spermatozoa from the caput, corpus and cauda epididymidis were separated and quantitated by tlc. 2. spermatozoa from the caput epididymidis had a significantly greater (p less than 0.05) content of phospholipid, cholesterol, cholesterol ester and free fatty acid than those from the cauda epididymidis. 3. spermatozoa from the corpus epididymidis had a significantly greater (p less than 0.05) content of monoglyceride than those from the caput epididymidis and a greater ... | 1977 | 318275 |
| [immunoblastic sarcoma (reticulum-cell sarcoma) of the gastro-intestinal tract in a case of dermatitis herpetiformis duhring (author's transl)]. | in a 43-year-old man who for 20 years was known to have dermatitis herpetiformis there co-existed, since 1974, a "dermatogenic enteropathy" with gastro-intestional symptoms. several small-intestine biopsies demonstrated severe partial to subtotal villous atrophy with crypt hyperplasia, as seen in gluten-sensitive enteropathy. at post-mortem there was an immunoblastic sarcoma - so-called reticulum-cell sarcoma - in the upper jejunum and abdominal lymph-nodes, which was presumably the immediate co ... | 1977 | 318987 |
| induction of escherichia coli and vibrio cholerae enterotoxins by an inhibitor of protein synthesis. | enterotoxigenic escherichia coli or vibrio cholerae 569b (inaba) grown in the presence of the antibiotic lincomycin, an inhibitor of protein synthesis, produced elevated levels of heat-labile enterotoxin or choleragen, respectively, as assayed by both vascular permeability factor and capacity to elicit fluid accumulation in rabbit ileal loops. this induction of enterotoxin did not reflect either a coupling of lincomycin resistance with increased enterotoxigenicity or an effect of lincomycin on c ... | 1977 | 319055 |
| temperature-sensitive r plasmid obtained from naturally isolated drug-resistant vibrio cholerae (biotype el tor). | a temperature-sensitive fi(-) r plasmid, pjy1, which confers resistance to chloramphenicol, streptomycin, and sulfonamide, was found in a drug-resistant strain of vibrio cholerae (biotype el tor) isolated in the philippines in 1973. the r plasmid is temperature sensitive for transferability but not for stability in the hosts. pjy1 is stably maintained either in v. cholerae or in escherichia coli at a range of culture temperatures from 27 to 42 degrees c. compatibility tests with reference r plas ... | 1977 | 319746 |
| [bovine renal tuberculosis in a farmer--contribution to the relationship between human and bovine tuberculosis]. | | 1977 | 319986 |
| comparison of the virulence of o:9,12 and o:4,5,12 salmonella typhimurium his+ transductants for mice. | the purpose of these experiments was to determine whether qualitative differences in the o repeat unit of the lipopolysaccharide of pathogenic salmonella species affected virulence for mice. o:4,5,12 and o:9,12 sister his+ transductants were derived from a virulent salmonella typhimurium. fermentation markers were introduced by transduction to differentiate these strains, and the strains were used as mixed challenge to cf1 and c57b1/6j mice. liver and spleen cultures of the mice of various inter ... | 1977 | 321351 |
| use of fluorescent antibody in studies of immunity to cholera in infant mice. | infant mice 8 days of age were infected orally with virulent, motile, classical or el tor strains of vibrio cholerae and with nonmotile mutants of low virulence derived from the same strains. at intervals of 8 and 12 h postinfection, frozen thin sections of the ileum were prepared, stained with fluorescein isothiocyanate-labeled rabbit anti-vibrio antibody, and examined with the fluorescence microscope. the motile organisms were present in larger numbers, especially at 12h, and had penetrated th ... | 1977 | 321353 |
| new culture medium for the presumptive identificaion of candida albicans and cryptococcus neoformans. | a new medium composed of tween 80, oxgall, caffeic acid, and davis agar (toc) that provides for the rapid presumptive identification of candida albicans and cryptococcus neoformans is described herein. c. albicans is differentiated from other yeasts by the sequential production of germ tubes and chlamydospores. in a comparison with cormeal agar control plates, there was an increase of chlamydospore-forming strains of c. albicans (97.1% versus 87.2%) and a decrease in the time required for chlamy ... | 1977 | 321472 |
| diarrhea due to escherichia coli in the rabbit: a novel mechanism. | a strain of escherichia coli o15 (rdec-1) isolated from several rabbits with diarrhea was examined to determine (1) whether the strain could produce diarrhea when administered by the orogastric route to other rabbits and (2) whether this strain was invasive or enterotoxigenic. strain rdec-1 produced diarrhea in 48 of 62 rabbits when given by the orogastric route in doses that ranged from 1.5 x 10(2) to 4 x 10(10) bacteria. the organism did not give a positive result in the 18-hr ileal loop or se ... | 1977 | 321703 |
| characterization of the chinese hamster ovary cell assay for the enterotoxins of vibrio cholerae and escherichia coli and for specific antisera, and toxoid. | the morphologic change in chinese hamster ovary (cho) cells that is associated with increased intracellular concentrations of adenosine 3':5'-cyclic phosphate (cyclic amp) provided a highly sensitive assay for the heat-liable enterotoxins of vibrio cholerae and escherichia coli. the similarity between the responses of cho cells and those of intestinal mucosa to enterotoxins was demonstrated by the inhibition of these effects by the ganglioside galactosyl-n-acetylgalactosaminyl [sialosyl] lactosy ... | 1977 | 323378 |
| the role of chemotaxis in the ecology of bacterial pathogens of mucosal surfaces. | | 1977 | 323724 |
| [history of microbiology in japan (6)]. | | 1977 | 325250 |
| reduction of reactivity of escherichia coli enterotoxins by intestinal mucosal components. | incubation studies involving rabbit and piglet small intestinal mucosal components and escherichia coli and vibrio cholerae enterotoxins were conducted at 37 and 4 degrees c. mucosal homogenate cytosol from rabbits did not significantly alter the reactivities of either cholera enterotoxin (ct) or e. coli labile enterotoxin (lt). however, mucosal homogenate cytosol from piglets was capable of neutralizing lt, though it had no effect on e. coli stable enterotoxin. lt became bound to piglet and rab ... | 1977 | 326677 |
| solubilization of chromatin with heparin and the isolation of nuclear membranes. | | 1977 | 327198 |