Publications

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neurotropic bovine astrovirus-associated encephalitis: an underdiagnosed disease in south america?we describe a case of neurotropic bovine astrovirus-associated encephalitis in a jersey dairy cow from the department of san josé, uruguay. this represents the second case of this condition reported in the southern hemisphere. the cow was the only one affected in a herd of 70 cows, showing neurological signs with a 2-day clinical course, before dying spontaneously. histopathological examination revealed lymphocytic, histiocytic, and plasmacytic meningoencephalitis with neuronal necrosis, without ...202134148730
sentinel coyote pathogen survey to assess declining black-footed ferret (mustela nigripes) population in south dakota, usa.as part of the national recovery effort, endangered black-footed ferrets (mustela nigripes) were reintroduced to the cheyenne river sioux reservation in south dakota, us in 2000. despite an encouraging start, numbers of ferrets at the site have declined. in an effort to determine possible causes of the population decline, we undertook a pathogen survey in 2012 to detect exposure to west nile virus (wnv), canine distemper virus (cdv), plague (yersinia pestis), tularemia (francisella tularensis), ...202133822142
west nile virus seroprevalence in an outdoor nonhuman primate breeding colony in south florida.west nile virus (wnv) was first detected in florida in july 2001, with 404 human cases reported to the centers for disease control and prevention as of february 2020. the subtropical climate of florida is ideal for the mosquitoes that transmit wnv. we investigated the wnv seroprevalence in 3 nhp species housed outdoors at the mannheimer foundation in south florida. from january to december 2016, 520 3 to 30 y old nhp were sampled at our 2 closed sites in homestead and labelle: 200 rhesus macaque ...202133441221
exposure to zoonotic west nile virus in long-tailed macaques and bats in peninsular malaysia.the role of wildlife such as wild birds, macaques, and bats in the spreading and maintenance of deadly zoonotic pathogens in nature have been well documented in many parts of the world. one such pathogen is the mosquitoes borne virus, namely the west nile virus (wnv). previous research has shown that 1:7 and 1:6 malaysian wild birds are wnv antibody and rna positive, respectively, and bats in north america may not be susceptible to the wnv infection. this study was conducted to determine the sta ...202033321964
virus infection of the cns disrupts the immune-neural-synaptic axis via induction of pleiotropic gene regulation of host responses.treatment for many viral infections of the central nervous system (cns) remains only supportive. here we address a remaining gap in our knowledge regarding how the cns and immune systems interact during viral infection. by examining the regulation of the immune and nervous system processes in a nonhuman primate model of west nile virus neurological disease, we show that virus infection disrupts the homeostasis of the immune-neural-synaptic axis via induction of pleiotropic genes with distinct fu ...202133599611
serologic survey of mosquito-borne viruses in hunter-harvested white-tailed deer (odocoileus virginianus), new york state.sera from white-tailed deer (wtd, odocoileus virginianus) hunter-harvested throughout new york state (nys), 2007-2015, were tested by plaque reduction neutralization for antibodies against nine mosquito-borne viruses from the families peribunyaviridae, flaviviridae, and togaviridae. overall, 76.1% (373/490) of sampled wtd were seropositive against at least one virus, and 38.8% were exposed to multiple viruses. the seropositivity rate in adult wtd (78.0%) was significantly greater (p < 0.0001) th ...202033350367
serologic survey for west nile virus in wild boars (sus scrofa) in poland.serum samples obtained from 474 wild boars (sus scrofa) were collected from june 2017 to september 2018 from various areas of northern and southern poland. serum samples were examined by enzyme-linked immunosorbent assay. however, west nile virus (wnv) antibodies were not detected. previous studies on wnv in poland have focused on experimental evidence and the presence of wnv antibodies in wild birds, horses, and humans, indicating a need for more surveys of domestic and wild mammals in poland.202133635970
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