| monitoring renal cryosurgery: predictors of tissue necrosis in swine. | to examine parameters for monitoring renal cryosurgery and correlate with histopathologic necrosis in a porcine model. parameters include: 1) tissue temperature, 2) distance of tissue from the cryosurgical probe insertion site, and 3) inclusion of tissue by the visible iceball. | 1998 | 9507886 |
| mechanisms of sex-ratio adjustment in domestic swine: reply to james | no abstract. copyright 1998 the association for the study of animal behaviour. | 1998 | 9514677 |
| multiple mechanisms may affect birth sex ratio in domestic pigs | no abstract. copyright 1998 the association for the study of animal behaviour. | 1998 | 9514678 |
| comparison of tissue oxygen-tension measurements by different devices. an experimental study in pigs. | the aim of this study was to evaluate measurements of subcutaneous oxygen tension (psco2) generated by three different monitors and to compare measurements obtained with and without the tonometer technique in a standardized animal model. seven domestic pigs weighing 20-28 kg were anaesthetized and mechanically ventilated. a pulmonary artery catheter was inserted for haemodynamic monitoring and temperature measuring. an external carotid artery was cannulated for blood pressure monitoring and bloo ... | 1998 | 9516658 |
| development and morphological variability of echinococcus granulosus. | characteristics are presented of echinococcus granulosus strobila from dogs experimentally infected with protoscolices from a single cyst isolated from the liver of a domestic pig in a central slovakian district. adult cestodes are characterized mainly by 28-32 hooks highly variable in shape and size; 26-51 testes situated mostly throughout the proglottis (1 or 3 rows behind the vitelline gland); a lobate ovary; the shape of the uterus, which in 10% of proglottides is more or less spherical, in ... | 1998 | 9521012 |
| deletion of a cd2-like gene, 8-dr, from african swine fever virus affects viral infection in domestic swine. | an african swine fever virus (asfv) gene with similarity to the t-lymphocyte surface antigen cd2 has been found in the pathogenic african isolate malawi lil-20/1 (open reading frame [orf] 8-dr) and a cell culture-adapted european virus, ba71v (orf ep402r) and has been shown to be responsible for the hemadsorption phenomenon observed for asfv-infected cells. the structural and functional similarities of the asfv gene product to cd2, a cellular protein involved in cell-cell adhesion and t-cell-med ... | 1998 | 9525608 |
| an amorphous hydrogel enhances epithelialisation of wounds. | hydrogel dressings are gaining increased clinical acceptance as a wound management modality. the purpose of this study was to compare the effect of three amorphous hydrogels with occlusive, control treatment (tegaderm) on healing of experimental wounds. eight partial-thickness cutaneous wounds (2.5 cm x 2.5 cm x 0.04 cm) were made, using an electrokeratome, and the four treatments were allocated by randomisation within a cephalad and a caudal region on each of six 60-kg domestic pigs. in total, ... | 1998 | 9534889 |
| chagas disease in the amazon basin: association of panstrongylus geniculatus (hemiptera: reduviidae) with domestic pigs. | just over 100 autochthonous cases of chagas disease are reported from the brazilian amazon basin. panstrongylus geniculatus (latreille) occurs throughout the region and is the known vector of trypanosoma cruzi, principal zymodeme 3 (z3) to the armadillo dasypus novemcinctus. in the small riverine community of furo do rio pau grande, pigsties adjoining houses were heavily infested with p. geniculatus, which repeatedly attacked local inhabitants. palm trees in the immediate vicinity were also infe ... | 1998 | 9538568 |
| 1998 scvir gary j. becker young investigator award. endovascular repair of arterial pseudoaneurysms with use of a perfusion balloon catheter. | pseudoaneurysms represent contained disruption of the arterial wall. iatrogenic pseudoaneurysms frequently complicate complex endovascular procedures. with use of an animal model, the authors attempted to determine the safety and efficacy of using a perfusion balloon catheter (pbc) to thrombose surgically created pseudoaneurysms. | 1998 | 9540901 |
| nine new cases of reciprocal translocation in the domestic pig (sus scrofa domestica l.). | nine pigs with decreased litter size or sired by boars with decreased litter size were found to be reciprocal translocation carriers. four large white animals (two females and two males) demonstrated translocations involving chromosomes 1 and 9 (1p-;9p+), 11 and 13 (11q+;13q-), 3 and 13 (3;13)(p1.5;q3.1), and 15 and 17 (15;17)(q1.3;q2.1). two large white x pietrain terminal boars demonstrated translocations involving chromosomes 11 and 16 (11;16)(p1.4;q1.4), and 6 and 14 (6;14)(q2.7;q2.1). the ( ... | 1998 | 9542161 |
| ultrasonic epithelial ablation of the lower esophagus without stricture formation. a new technique for barrett's ablation. | the premalignant potential of barrett's esophagus has stimulated efforts to find a way to ablate the columnar epithelium in order to reheal the area with squamous epithelium, thus obviating the cancer risk. this study describes and evaluates a new technique using ultrasonic energy to ablate the epithelium of the lower esophagus in a porcine model. | 1998 | 9543526 |
| comparative biomembrane permeation of tacrine using yucatan minipigs and domestic pigs as the animal model. | tacrine (tha), a centrally acting acetylcholine-esterase inhibitor, is presently administered perorally for the treatment of alzheimer's disease (ad). however, its low bioavailablity (i.e., 17%) and short half-life (2-4 h) demand the search for alternative routes of administration. the primary objective of this study was to assess the potential of absorptive mucosae and skin as routes for improving the systemic delivery of tha. the yucatan minipig, which has been used increasingly in biomedical ... | 1998 | 9548896 |
| hemodynamic effects of the laparoscopic pneumoperitoneum during sepsis in a porcine endotoxic shock model. | the authors compared the hemodynamic effects of laparoscopic intervention with conventional laparotomy in an endotoxic shock model in the pig. | 1998 | 9563532 |
| low molecular weight heparin prevents the pulmonary hemodynamic and pathomorphologic effects of endotoxin in a porcine acute lung injury model. | tumor necrosis factor alpha (tnf-alpha) activity, platelet and neutrophil degranulation and margination, and increased vascular permeability are central to the pathophysiology of endotoxin-mediated acute lung injury. nonanticoagulant activities of low molecular weight heparin (lmwh) include solubilization of the tnf-alpha receptor protein, inhibition of neutrophil adhesion, and regulation of thromboxane b2 (txb2) biosynthesis. in this study, we evaluated the ability of lmwh to modulate tnf-alpha ... | 1998 | 9565256 |
| body weight distribution and organ size in newborn swine (sus scrofa domestica) -- a study describing an animal model for asymmetrical intrauterine growth retardation. | normal growth is the expression of the genetic potential to growth which is neither abnormally constrained nor promoted by internal or external factors. restricted fetal growth is common in human pregnancy and is associated with increased perinatal morbidity and mortality. because of ethical restrictions, pathogenetical studies are necessarily dependent on appropriate animal models. in the studies presented, evidence will be provided that the naturally occurring distribution of body weight in ne ... | 1998 | 9570503 |
| growth and structural features of the adult stage of ascaris suum (nematoda, ascaridoidea) from experimentally infected domestic pigs. | for studying the morphogenesis of the adult stage of ascaris suum, worms were obtained from experimentally infected domestic pigs. structural and morphometric features of a. suum are analyzed by light and scanning electron microscopy. it was shown that the increase in length of the worm from days 35 to 56 is based on a region-specific lengthening of individual transverse annuli in the cuticle. an increased worm size also results in an increased diameter of different cuticular sense organs. it is ... | 1998 | 9576498 |
| pseudorabies in the european wild boar from eastern germany. | sera collected from european wild boar (sus scrofa) shot in eastern germany between january 1991 and december 1994 were tested for antibodies to pseudorabies virus (prv). of 3,143 sera tested, 281 (8.9%) and 13 (0.4%) were positive and suspect in an enzyme-linked immunosorbent assay (elisa), respectively. the specificity of the reactions was confirmed by detection of neutralizing antibodies in 220 sera (74.8%) and by immunoblotting. analysis of host age and sex of the animals, temporal and spati ... | 1998 | 9577771 |
| the timing of congenital brachial plexus injury: a study of electromyography findings in the newborn piglet. | permanent congenital brachial plexus palsy is a recognized serious complication associated with shoulder dystocia. the timing and etiology of this injury remains controversial. previous authorities have used adult-derived, non-brachial plexus data to extrapolate the anticipated timing for electromyographic denervation changes to date such injuries in the newborn. with use of a domestic swine model, this investigation tests the hypothesis that electromyographic evidence of brachial plexus denerva ... | 1998 | 9579430 |
| ventilatory strategies affect gas exchange in a pig model of closed-chest cardiac compression. | to identify the arterial and mixed venous blood gas changes caused by different ventilatory strategies during resuscitation from ventricular fibrillation in a pig model of closed-chest cardiac compression. | 1998 | 9581140 |
| the axillary tree as a source of musculocutaneous and fasciocutaneous flaps in a fixed-skin porcine model. | our understanding of muscle, fascia, and skin flap physiology is based largely on data obtained from rodent, rabbit, or canine models. the presence of a well-developed panniculus carnosus confounds the extrapolation of data from these animals to humans. this study attempted to define microsurgically applicable musculocutaneous and fasciocutaneous flaps in the pig that would be comparable to flaps commonly used in humans. lead oxide was injected into each axillary artery of three standard white d ... | 1998 | 9600430 |
| effects of diverse developmental environments on neuronal morphology in domestic pigs (sus scrofa). | potential effects of environmental rearing conditions on the brains of farm animals have not been examined experimentally, with the exception of one report for pig somatosensory cortex. the goal of the present experiment was to determine whether different developmental environments in use in agricultural production units affect neuronal morphology in the pig cerebral cortex. littermate female pigs (gilts) were cross-fostered at birth and reared in either an indoor (n = 6) or outdoor (n = 6) prod ... | 1998 | 9602033 |
| regulation of conceptus development and attachment in pigs. | implantation/placentation in domestic pigs is preceded by synthesis of oestrogen by the conceptus to maintain functional corpora lutea throughout pregnancy and a rapid morphological transformation of conceptuses from spherical to long filamentous thread-like structures. initial conceptus expansion, reaching a metre in length, not only delineates the surface area for placental attachment, but also provides the mechanism for delivery of oestrogen to signal events necessary for placentation through ... | 1997 | 9602725 |
| a conserved african swine fever virus right variable region gene, l11l, is non-essential for growth in vitro and virulence in domestic swine. | the right variable region of the african swine fever virus (asfv) genome is known to contain genes with functions involving virus virulence and host range in swine. a novel open reading frame, orf l11l, which was absent in the non-pathogenic, cell culture-adapted european isolate ba71v, was identified in the pathogenic african isolate malawi lil-20/1. the location of l11l in the right variable region, together with its absence in ba71v, suggested that l11l may have a function in virus virulence ... | 1998 | 9603334 |
| the relationship of ischemia-reperfusion injury of transplanted lung and the up-regulation of major histocompatibility complex ii on host peripheral lymphocytes. | this study was designed to examine the relationship between ex vivo preservation time of the transplanted lung and the extent of injury and to relate this to the severity of rejection with and without allogenicity. | 1998 | 9605065 |
| determination of stereotaxic coordinates for the hippocampus in the domestic pig. | in this study a stereotaxic instrument and a stereotaxic procedure based on external skull structures, to be used in prepubertal male landrace pigs weighing less than 30 kg, is described. the instrument represents an adaptation of the apparatus designed by marcilloux et al., brain res bull 1989;22:591-597, but we have modified the instrument for stereotaxic procedures based on external skull structures, instead of intracerebral structures necessitating ventriculography (marcilloux et al., brain ... | 1998 | 9606047 |
| arthropod succession patterns onto burnt carrion in two contrasting habitats in the hawaiian islands. | decomposition studies were conducted using carcasses of domestic pigs, sus scrofa l., one burned and the other unburned (the control) to determine effects of burning on arthropod succession patterns. the burnt carcass corresponded to a cgs level #2 burn victim. the studies were conducted in two contrasting habitats, both on the island of oahu. the first was conducted in a xerophytic habitat from 1 sept. 1995 through 1 oct. 1995 while the second was conducted in a rainforest habitat from 29 april ... | 1998 | 9608693 |
| laparoscopic cryosurgery of the kidney in the porcine model: an acute histological study. | to verify histologically whether cryosurgery of the kidney can be accomplished reproducibly without injuring adjacent structures, using a combination of ultrasound and laparoscopic guidance. | 1998 | 9610574 |
| effect of anion secretion inhibitors on mucin content of airway submucosal gland ducts. | in porcine bronchi, inhibition of both cl- and hco3- transport is required to block the anion secretion response to ach and to cause mucus accumulation within ach-treated submucosal gland ducts [s. k. inglis, m. r. corboz, a. e. taylor, and s. t. ballard. am. j. physiol. 272 (lung cell. mol. physiol. 16): l372-l377, 1997]. in this previous study, a combination of three potential hco3- transport inhibitors [1 mm acetazolamide, 1 mm dids, and 0.1 mm dimethylamiloride (dma)] was used to block carbo ... | 1998 | 9612291 |
| [experimental evaluation of superparamagnetic iron oxide particles in pulmonary mr angiography]. | initial experimental results of contrast-enhanced pulmonary mr angiography using the new superparamagnetic iron oxide blood pool agent feo-bpa. | 1998 | 9617369 |
| plasma catecholamine levels following tracheal and intravenous epinephrine administration in swine. | we compared plasma epinephrine levels after three different tracheal epinephrine application techniques and intravenous injection in male and female anesthetized and paralyzed domestic pigs. epinephrine was administered intravenously (10 microg/kg) (group i.v.) or tracheally (100 microg/kg) either by direct injection into the upper end of the tracheal tube (group tube), via a suction tube placed into the bronchial system (group catheter) or using an edgar tube (group edgar), each group: n = 8. a ... | 1998 | 9627070 |
| african swine fever: a disease characterized by apoptosis. | the cell tropism, organ distribution and resultant pathology of african swine fever were compared in domestic pigs infected with lethal (malawi) and sublethal (malta) isolates of african swine fever virus (asfv). after infections with both isolates, asfv was predominantly localized in cells of the mononuclear phagocytic system and was not observed in endothelial cells in lymphoid tissue. more severe tissue destruction and cell depletion, associated with high levels of infected macrophages, were ... | 1998 | 9634085 |
| the pathogenesis of african swine fever in the resistant bushpig. | bushpigs and warthogs are natural reservoir hosts of african swine fever virus (asfv) in the wild, showing no clinical signs of disease when infected with the same highly virulent isolates of asfv that induce rapid, haemorrhagic death in domestic pigs. in contrast to domestic pigs, infection of bushpigs with malawi isolate results in low levels of virus replication and lymphocyte apoptosis within the spleen, and a relatively low spread of virus to other lymphoid tissues. however, at 10 days post ... | 1998 | 9634086 |
| membrane bounded dense bodies (mbb) of the domestic pig pinealocytes--current state of knowledge. | the results of our former investigations concerning the pig pinealocyte organelles named membrane bounded dense bodies (mbb) have been summarized. the presence of mbb is the most conspicuous morphological feature of pinealocytes of genus suidae. the relative volume of mbb in the cell bodies of pinealocytes in adult domestic pigs ranges from 8% to 16% of whole cytoplasm. on the basis of their morphology, membrane bounded bodies were divided into two main types: mbb-1 and mbb-2. dense bodies of mb ... | 1997 | 9646700 |
| the tissue effects of ultrasound-assisted lipoplasty. | the objective of our study was to investigate the effects of ultrasonic energy on tissues, using a porcine model, performed under various instrumental and procedural parameters. domestic pigs were anesthetized and prepared for surgery. an incision was made on the side of the hip randomly assigned to the right or left side. tumescence solution was infiltrated via a blunt tip, small diameter cannula, followed by performance of standard liposuction. on the contralateral side, a similar incision was ... | 1998 | 9655430 |
| african swine fever virus infection of the bushpig (potamochoerus porcus) and its significance in the epidemiology of the disease. | warthog (phacochoerus aethiopicus), giant forest hog (hylochoerus meinertzhageni) and bushpig (potamochoerus porcus) are known to be susceptible to infection with african swine fever (asf) virus. little however, is known about the ecology of the disease in the bushpig. this study has shown that the bushpig remains viraemic for between 35 and 91 days following infection during which time it is able to infect the tick vector o. moubata. these ticks were able to transmit the disease to pigs. the vi ... | 1998 | 9659687 |
| morphologic, biometric, and isoenzyme characterization of trichuris suis. | trichuris suis isolates were collected from the cecum of sus scrofa domestica (pig) and s. s. scrofa (wild boar). morphology and biometry studies were carried out. morphology studies showed the existence of typical caudal papillae in males of t. suis from wild boars, but no other difference was observed in the biometric parameters (total length, esophageal length, posterior-portion body length, and spicular length) of t. suis isolated from either host. individual extracts were subjected to malat ... | 1998 | 9660144 |
| obliterative lesions in small airways in an immunosuppressed porcine heterotopic bronchial allograft model. | we have recently developed a heterotopic large-animal model for research into obliterative lesions in small airways caused by allograft rejection. in this model, the small airways of subcutaneously implanted allografts gradually obliterate, whereas autografts remain patient. twenty lung fragments and 20 segments of bronchi were implanted in domestic pigs weighing 20 kg from non-related donors. the histology of five animals receiving daily cyclosporine a (csa) (10 mg/kg), azathioprine (2 mg/kg) a ... | 1998 | 9665049 |
| nutritional state, growth rate, and morphology after total gastrectomy with restoration of duodenal passage or roux-en-y oesophagojejunostomy with or without a pouch: an experimental study in pigs. | to compare the effect of restoration of duodenal continuity by a roux-en-y oesophagojejunostomy with or without a pouch on nutritional state, growth, and morphology after total gastrectomy in pigs. | 1998 | 9667472 |
| detecting gastrointestinal hypoperfusion during cardiac tamponade in pigs: a role for nitric oxide tonometry? | to evaluate different techniques and regional approaches for detecting critical reductions in gastrointestinal (gi) perfusion. | 1998 | 9671377 |
| influence of artificial light regimens on sexual maturation and boar taint in entire male pigs. | to determine if artificial light regimens could influence sexual maturation and boar-taint factors in entire male pigs, 48 weaned, winter-born crossbred males (52-64 days old) were exposed to either a natural photoperiod (january-june, 60 degrees n, control, n= 16) or to one of two artificial photoperiods (1400 1x) in light-sealed rooms. we exposed the spring group to an increasing artificial photoperiod (january - june, 60 degrees n, n=16) and the autumn group to a decreasing one (july-december ... | 1998 | 9672668 |
| [the situation of classical swine fever in wild boars in the european community and selected aspects of disease transmission]. | the situation of classical swine fever (csf) in europe is described on the basis of the literature. in the european community, csf is present among wild boars in germany (federal states mecklenburg-western pomerania, brandenburg and lower saxony), in france (northern vosges) and in italy (regio emìlìa romagna in 1997 and sardinia--enzootically infected). infected wild boars are important as a source of infection for domestic pigs in germany. selected aspects of the transmission of csf virus from ... | 1998 | 9674308 |
| systemic and regional pco2 gradients as markers of intestinal ischaemia. | we evaluated the response of mixed venous-arterial carbon dioxide (pco2) to severe intestinal ischaemia produced by gradual occlusion of the superior mesenteric artery (sma). | 1998 | 9681782 |
| isolation of putative olfactory receptor sequences from pig nasal epithelium. | binding to olfactory receptors is the first step in odorant and pheromonal recognition and discrimination. these receptors constitute one of the most important, although poorly known, families of neuronal receptors. in this study we used degenerated oligonucleotides and a rt-pcr approach to selectively amplify olfactory receptors in the nasal epithelium of the domestic pig sus scrofa. several combinations of oligonucleotide were tested and allowed the isolation of eleven different partial sequen ... | 1998 | 9682823 |
| stent versus endovascular graft healing characteristics in the porcine iliac artery. | to evaluate the healing characteristics of stents versus endovascular grafts in the porcine iliac artery. | 1998 | 9684832 |
| transthoracic induction of a hiatal hernia in domestic swine. | with the common performance of laparoscopic nissen fundoplication for gastroesophageal reflux disease, there is renewed interest in the pathophysiology and potential histologic consequences of hiatal hernias. however, in vivo model exists that both reliably reproduces the hiatal hernia and is amenable to subsequent laparoscopic repair. | 1998 | 9685543 |
| [protective effect of labetalol on cardiovascular consequences of brain death in the swine]. | assessment of the preventive effect on cardiovascular changes following experimental brain death (bd) in the pig by pretreatment with labetalol, an alpha and beta adrenoreceptor blocking agent. | 1997 | 9686073 |
| [mri-guided percutaneous nephrostomy of the contrast-enhanced, nondilated upper urinary tract: initial experimental results]. | to evaluate technique and practicability of mr-guided percutaneous nephrostomy (mrpcn) in an animal model. | 1998 | 9687955 |
| animal model of acute deep vein thrombosis. | to develop an animal model of acute deep vein thrombosis (dvt). | 1998 | 9688802 |
| detection of african swine fever virus in infected pig tissues by immunocytochemistry and in sity hybridisation. | the techniques for determining cellular sites of establishment and persistence of african swine fever virus (asfv) were established in susceptible domestic pigs and the resistant african reservoir hosts, the warthog and bushpig. detection, both in vitro and in vivo, was achieved by in situ hybridisation and immunocytochemistry, focusing principally on specific probes for vp73, a major capsid protein. hybridisation of radio-labelled probes for dna and rna was relatively insensitive and time consu ... | 1998 | 9694328 |
| retinoids are endogenous to the porcine blastocyst and secreted by trophectoderm cells at functionally-active levels. | retinoic acid and its isomers are the major morphogens in vertebrate development. for mammals, it was previously considered that circulating retinoic acid was recruited from the uterine environment, to influence embryonic differentiation, morphogenesis and development. here we report that retinoic acid is endogenous to the blastocyst of the domestic pig, sus scrofa, as detected by high pressure liquid chromatography. furthermore, using a continuous, normal line of porcine trophectoderm cells, te ... | 1998 | 9694636 |
| is growth influencing diameter and function of laparoscopic tesa hepaticojejunostomy? a comparison of adult minipigs and juvenile domestic swine. | current treatment of obstructive jaundice includes endoscopic stenting and open surgical bypass. to combine the advantages of surgical bypass with the minimal invasive approach of endoscopic stenting we developed a laparoscopic technique, transient endoluminally stented anastomosis (tesa). as shown previously, small-diameter anastomoses (e.g., hepaticojejunostomy) by tesa technique can be performed reliably in growing domestic swine. this further preclinical trial was designed to exclude growth ... | 1998 | 9700619 |
| transjugular intrahepatic portosystemic shunt in a porcine model: histologic characteristics at the early stage. | the authors attempted to determine the histologic processes that take place during development of stenosis after transjugular intrahepatic portosystemic shunt (tips) creation. | 1998 | 9702265 |
| three-dimensional 87rb imaging of isolated pig hearts: effects of regional ischemia. | the aim of this work was to investigate whether 1) rb uptake is reduced in ischemic myocardium, and 2) 87rb three-dimensional (3d) imaging can detect the ischemic area. hearts of domestic pigs (n = 8, 20-30 kg) were perfused retrogradely with krebs-henseleit buffer in a 7-t, 40-cm horizontal bore magnet interfaced with bruker mslx spectrometer. control (c) and ischemic (i) (45 min ligation of the left anterior descending coronary artery (lad)) hearts were loaded with rb+ by perfusion with a rb(+ ... | 1998 | 9702698 |
| technetium-99m-nitroimadazole uptake in a swine model of demand ischemia. | nitroheterocycles are electron affinic, lipophilic compounds that are retained in hypoxic tissue. this study was designed to test the hypothesis that 99mtc-5-oxa-amine-oxime nitroimadazole (bms-194796) is retained in ischemic myocardial tissue in a swine model of demand ischemia and that the retained tracer can be imaged in vivo. | 1998 | 9708532 |
| endotracheal drug delivery followed by a 90-degree torso tilt in a swine model of cardiac arrest. | prehospital providers are often unable to obtain intravenous (i.v.) access in cardiac arrest victims. while several drugs can be administered via the endotracheal (et) route, serum drug levels are lower than those obtained with the i.v. route. the authors hypothesized that a 90-degree torso tilt after et drug administration would increase drug levels. | 1997 | 9709362 |
| flap flow and cardiac output as functions of pulmonary artery wedge pressure: experimental study in the pig. | cardiac output (co) is redistributed during hypovolemia, but it has not been clearly documented how this influences flap perfusion. simultaneous changes in perfusion of a muscle flap and co as modulated by reductions in cardiac filling pressure were compared in a pig model. the hypothesis was that flap flow (ff) would remain relatively constant as co was reduced, according to the frank-starling curve. under general anesthesia, five domestic pigs were utilized. following right carotid artery cann ... | 1998 | 9714037 |
| midazolam-fentanyl-isoflurane anaesthesia is suitable for haemodynamic and fluid balance studies in pigs. | the domestic pig is a useful model in certain areas of biomedical research. effective use of this species is often encumbered by lack of reference values in conscious as well as anaesthetized animals. anaesthesia itself influences physiological and biological variables; the anaesthetic technique often affects experimental results. the relationship between anaesthesia and haemodynamics is well characterized in man, but less established in pigs. we studied the effect of midazolam-fentanyl-isoflura ... | 1998 | 9718480 |
| molecular basis for the dominant white phenotype in the domestic pig. | the change of phenotypic traits in domestic animals and crops as a response to selective breeding mimics the much slower evolutionary change in natural populations. here, we describe that the dominant white phenotype in domestic pigs is caused by two mutations in the kit gene encoding the mast/stem cell growth factor receptor (mgf), one gene duplication associated with a partially dominant phenotype and a splice mutation in one of the copies leading to the fully dominant allele. the splice mutat ... | 1998 | 9724328 |
| serological and immunohistochemical study of african swine fever in wild boar in spain. | a serological and immunohistochemical study of african swine fever was carried out in wild boar killed in seven municipalities in the north of the province of córdoba during two hunting seasons (1991-92 and 1992-93), when the area was affected by the disease. fourteen of 147 wild boar analysed by elisa and immunoblotting had antibodies to african swine fever virus. the immunohistochemical study revealed that four cases (two seropositive and two seronegative) showed immunoreactivity to the anti-v ... | 1998 | 9725185 |
| pulmonary function after one-lung ventilation in newborns: the basis for neonatal thoracoscopy. | to maintain good exposure during major video-assisted thoracic surgery it is necessary to deflate completely the ipsilateral lung. however, little is known about the effects of one-lung ventilation (olv) on pulmonary function in newborn patients. | 1998 | 9725400 |
| measurement of adenosine concentration in aqueous and vitreous. | the release of adenosine by the ischemic retina may be an initial signal in the development of ischemic macular edema and neovascularization. the levels of adenosine have never been quantified in ocular fluids. in this study, a technique was developed for in vivo measurement of the concentration of adenosine in aqueous and vitreous. | 1998 | 9727417 |
| experimental tricyclic antidepressant toxicity: a randomized, controlled comparison of hypertonic saline solution, sodium bicarbonate, and hyperventilation. | we sought to compare the effects of hypertonic sodium chloride solution (hts), sodium bicarbonate solution, and hyperventilation (hv) on severe tricyclic antidepressant (tca) toxicity in a swine model. | 1998 | 9737495 |
| morphologic peculiarities of the renal cortical vasculature connected with blood redistribution in the kidney of the domestic pig. | the cortical blood vessels from 2 to 8 month old camborow hybrid pigs and belgium landrace pigs were studied using histologic and semithin sections as well as corrosion casts and cleared preparations of intravascular injection. it was established that the cortical blood vessels of the porcine kidney possess peculiarities that may regulate the redistribution of blood in the cortex. these peculiarities were found in the interlobular arteries, in the efferent arterioles of midcortical nephrons, in ... | 1998 | 9741149 |
| effects of weaning and restraint stress on glucocorticoid receptor binding capacity in limbic areas of domestic pigs. | changes in glucocorticoid receptor (gr) binding in different brain areas were investigated in neonatal and adult pigs exposed to psychological stress (weaning) and a physical stressor (repeated snaring). the gr binding was significantly decreased 4 days after weaning in both the hippocampus and the amygdala, but there were no changes in the hypothalamus. repeated snaring of adult pigs resulted in a significant diminished gr binding only in the hippocampus. | 1998 | 9757073 |
| five new cases of reciprocal translocation in the domestic pig. | five new cases of reciprocal translocation in the domestic pig are described. three of them, rep(3;5)(p1.3;q2.3), rep(6;13)(p1.5;q4.1) and rep(13;17)(q4.1;q1.1) were found in boars with decreased litter size. the remaining two were identified in animals karyotyped before reproduction: a young boar, rep(4;6)(q2.1;q2.8), and a gilt, rep(2;14)(q1.3;q2.7). a parental origin by inheritance of the translocations was established in cases 1, 4, and 5. a decrease in prolificacy of 43% and 34% was estimat ... | 1998 | 9760870 |
| the toxic mechanism and metabolic effects of atractyloside in precision-cut pig kidney and liver slices. | the toxic and cellular metabolic effects of atractyloside, a diterpenoid glycoside, which causes fatal renal and hepatic necrosis in vivo in animals and humans, have been investigated in tissue slices prepared from male domestic pig kidney and liver. precision-cut slices (200 microm thick) were incubated with atractyloside at concentrations of 200 microm, 500 microm, 1.0 mm and 2.0 mm for 3 h at 37 degrees c and changes in lipid profile and pyruvate-stimulated gluconeogenesis investigated. lipid ... | 1998 | 9765068 |
| left ventricular functional improvement after transmyocardial laser revascularization. | transmyocardial laser revascularization has been used to treat patients with end-stage coronary artery disease that is not amenable to standard revascularization. although there is evidence of angina relief and quality of life enhancement, there is little information concerning improvement in myocardial contractility. the purpose of this study was to determine whether transmyocardial laser revascularization improves myocardial function in chronically ischemic myocardium. | 1998 | 9768921 |
| diving seals, ischemia-reperfusion and oxygen radicals. | the cardiovascular adaptations of seals that contribute to their ability to tolerate long periods of diving asphyxial hypoxia result in episodic regional ischemia during diving and abrupt reperfusion upon termination of the dive. these conditions might be expected to result in production of oxygen-derived free radicals and other forms of highly reactive oxygen species. seal organs vary during dives with respect to the degree and persistence of ischemia. myocardial perfusion is reduced and interm ... | 1998 | 9773490 |
| review of taeniasis in asia. | although asian taenia is closely related to t. saginata, it is a genetically distinct entity and can be distinguished from the classical t. saginata. man is the only definite host of this parasite. the domestic pig and wild boar in taiwan as well as domestic pig in korea have been determined to be the natural intermediate hosts. moreover, the pig has been demonstrated to be the most favorable experimental intermediate host. the cysticerci are situated mainly in the liver. they are smaller than t ... | 1995 | 9774987 |
| efficient debridement of necrotic wounds using proteolytic enzymes derived from antarctic krill: a double-blind, placebo-controlled study in a standardized animal wound model. | wound healing can be accelerated by removing necrotic tissue. various methods of wound debridement have been developed, including enzymatic debridement. recently potent proteolytic enzymes were isolated from the intestine of euphausia superba (antarctic krill) that might be useful for degrading necrotic tissue. the purpose of this study was to evaluate the debriding properties of krill enzymes, using a specially designed animal model and a computerized analysis system. in 10 female domestic pigs ... | 1998 | 9776850 |
| african swine fever virus nl gene is not required for virus virulence. | previously, we described a highly conserved nonessential african swine fever virus (asfv) right variable region gene, nl. deletion of nl from the european pathogenic isolate e70 resulted in almost complete attenuation of the virus in domestic swine. to study gene function further, nl gene deletion mutants were constructed from two pathogenic african asfv isolates, malawi lil-20/1 (mal) and pretoriuskop/96/4 (pr4). unexpectedly, both mal (mal-deltanl) and pr4 (pr4deltanl) null mutants remained hi ... | 1998 | 9780062 |
| effect of hypertonic saline solution and dextran on ventricular blood flow and heart-lung interaction after hemorrhagic shock. | hypertonic saline solutions may have beneficial hemodynamic effects in the resuscitation of hemorrhagic shock. the effects on cardiac function and potential interaction with lung function are controversial and served as the basis for this study. | 1998 | 9780983 |
| pigs in space: spatial memory and its susceptibility to interference. | this study provided basic information about spatial memory in the domestic pig, sus scrofa and examined how susceptible it is to disruption by environmental stimuli. eight male pigs were tested individually in a foraging arena. each day, they entered the arena to search for food randomly located in one of 10 enclosed areas (search trial). after finding and eating the food, they were removed from the arena for a retention interval, and then allowed back in to relocate the food in the same area as ... | 1997 | 9794774 |
| characterisation of pseudorabies virus isolated from wild boar (sus scrofa). | seroepidemiological evidence had suggested that pseudorabies (aujeszky's disease) virus (prv) infections occur in the european wild boar population in eastern germany, although attempts to isolate the causative agent had failed. in 1995 and 1996, five virus isolates were recovered from latently infected wild boar originating from two regions where the disease was endemic. the isolates were identified as prv by immunofluorescence and neutralisation with specific sera and grouped as prv type i. co ... | 1998 | 9795404 |
| combined effects of angiotensin converting enzyme inhibition and angiotensin ii receptor antagonism in conscious pigs with congestive heart failure. | the goal of this study was to determine if the hemodynamic effects of the combined administration of an angiotensin converting enzyme (ace) inhibitor and angiotensin ii type 1 (at1) receptor antagonist are greater than those produced by either of these agents administered individually during heart failure. | 1998 | 9798526 |
| epidemiology of echinococcus multilocularis and e. granulosus in central europe. | two species of echinococcus are known to occur in central europe, namely e. multilocularis and echinococcus granulosus, causing the alveolar and the cystic form of echinococcosis in humans, respectively. recent studies have shown that in central europe e. multilocularis occurs further north, south and east than previously anticipated. this parasite is endemic in belgium, luxembourg, france, switzerland, liechtenstein, austria, germany, poland, and the czech republic. the prevalence rates of e. m ... | 1997 | 9802089 |
| angiographic and histological evaluation of porcine retinal vascular damage and protection with perfluorocarbons after massive air embolism. | we have previously shown that perfluorocarbon emulsions (pfes) reduce the severity of cerebral injury (indicated by infarct, reduced blood flow, and depressed eeg) induced by air embolism during cardiopulmonary bypass (cpb). this study used retinal fluorescein angiography to define the mechanisms of cerebral injury and to determine the efficacy of pfes in cerebral protection. these angiographic findings were correlated to previously reported histologic findings. | 1998 | 9804654 |
| genetic and experimental evidence for cross-species infection by swine hepatitis e virus. | prior to the recent discovery of the swine hepatitis e virus (swine hev) in pigs from the midwestern united states, hev was not considered endemic to this country. since swine hev is antigenically and genetically related to human strains of hev, it was important to characterize this new virus further. the infectivity titer of a pool of swine hev in pigs was determined in order to prepare a standardized reagent and to evaluate the dose response in pigs. although the sequence of swine hev varied e ... | 1998 | 9811705 |
| shigella infection as observed in the experimentally inoculated domestic pig, sus scrofa domestica. | the domestic pig, sus scrofa domestica, was investigated as a potential animal model for shigellosis. we examined the effects of pig age, pig breed and antibiotic pretreatment upon shigella infection. shigella dysenteriae, and shigella flexneri (both virulent and avirulent strains) were utilized. our results indicated that young (4-week-old), conventionally re ared, domestic pigs were routinely, but briefly, colonized (average=3.5+/-2.5 days) following oral or gavage administration ofs. flexneri ... | 1998 | 9817822 |
| [practical implementation of control measures against highly contagious animal diseases in the territory of the european union exemplified by classical swine fever]. | the reasons for abandoning prophylactic vaccination against highly contagious animal diseases in the european union on principle are illustrated. the practical implementation of control measures under the current framework are explained with respect to an outbreak of classical swine fever, emphasizing the role of the local crisis center, the veterinary diagnostic laboratories and the need for an overall control and coordination of the campaign at the regional level. in view of the continuous ris ... | 1998 | 9818462 |
| ex vivo comparison of four lithotripters commonly used in the ureter: what does it take to perforate? | we hoped to determine the number of pulses and energy needed to create acute ureteral perforations with four different lithotripters in a reproducible ex vivo model. a simple model was constructed to control variables in the testing such as wall thickness, intraluminal pressure, distance between the probe tip and ureter, and power delivered to tissue. segments of domestic pig ureter were prepared and fixed in position in a normal saline (ns) bath at room temperature. we then attempted perforatio ... | 1998 | 9847062 |
| utility of the harmonic scalpel for laparoscopic partial nephrectomy. | laparoscopic partial nephrectomy (lpn) remains a technically challenging procedure largely because of the lack of methods for obtaining consistent parenchymal hemostasis. the objective of this study was to determine if the extent of resection influences the ability of the harmonic scalpel to achieve hemostasis and to define the cases in which the harmonic scalpel is appropriate for lpn. thirty lpns were performed in a 25-kg domestic pig model. the blunt blade of the laparoscopic harmonic scalpel ... | 1998 | 9847067 |
| the soft tissue cover of the mandibular condyle. differentiation in histological forms and age-related changes of aggrecan- and versican-like proteoglycans. | age-related changes of the composition of the extracellular matrix of the soft tissue cover of the mandibular condyle (stc), especially of the large proteoglycans, have been investigated. proteoglycans were extracted from the stc of neonatal, juvenile and adult domestic pigs, fractionated by density gradient centrifugation and analyzed by electrophoresis/western blotting. experiments revealed firstly that a large cs/ks proteoglycan (aggrecan) is an essential constituent of the stc at all ages. t ... | 1998 | 9857606 |
| [the function of nitric oxide in the necrosis of avulsed skin flap in domestic pig]. | to investigate the function of nitric oxide (no) and nitric oxide synthetase (nos) inhibitor, n-nitro-l-arginine methyl ester (l-name), the skin avulsion model was made in the lower extremity of pig. the methods of measurement of size of the survived flap, weighing, immunocytochemistry and hybridization in situ were employed, so that the survival surface area of flaps, tissue wet/dry weight ratio, no content in the serum, gene expression of no and nos content in the flap tissue were determined, ... | 1997 | 9867957 |
| expression pattern of extracellular matrix proteins in the pancreas of various domestic pig breeds, the goettingen minipig and the wild boar. | in spite of progress in biotechnology, isolation of porcine pancreatic islets remains a difficult task with unpredictable results. one reason could be the lack of knowledge as to the expression of extracellular matrix proteins in porcine exocrine and endocrine tissues, particularly in "islet capsules". such proteins are subject to digestion by proteases, yet they might have a protective function for the fragile islets. | 1997 | 9869860 |
| characterization of reciprocal translocations in pigs using dual-colour chromosome painting and primed in situ dna labelling. | we report the use of dual-colour chromosome painting to determine the exact nature of certain chromosome rearrangements observed in the pig (sus scrofa domestica). the chromosomal abnormalities were detected by gtg- and rbg-banding techniques. the initially proposed interpretations were: (1) rcp(6;13)(p1.5;q4.1); (2) rcp(11;16)(p1.4;q1.4); (3) rcp(6;16)(p1.1;q1.1); (4) rcp(13;17)(q4.1;q1.1); (5) rcp(6;14)(q2.7;q2.1); (6) rcp(3;5)(p1.3;q2.3); (7) rcp(2; 14)(q1.3;q2.7); (8) rcp(15;17)(q1.3;q2.1). ... | 1998 | 9872665 |
| functional mr imaging of the porcine kidney: physiologic changes of prolonged pneumoperitoneum. | increased intraabdominal pressure (ipa) during laparoscopy has been associated with decreased urine output. the purpose of this study was to use a noninvasive mri technique to measure renal vessel flow velocity and change in differential renal medulla and cortex perfusion during pneumoperitoneum. | 1997 | 9876643 |
| facilitating intracorporeal colorectal anastomoses. | an experimental study was undertaken to evaluate whether a previously described technique for laparoscopic sigmoid resection with intracorporeal resection-anastomosis and specimen removal via a suprapubic incision could be facilitated and applied to the rectum. | 1998 | 9876710 |
| heterogeneity of myocardial edema in isolated pig hearts after perfusion with different types of cardioprotective solutions. | the extent and distribution of myocardial edema induced by perfusion with cardioprotective solutions is of great interest. domestic pig hearts (n = 12) were perfused in situ after aortic cross clamping either with bretschneider's cardioplegic solution (htk, 4 degrees c, n = 3), with a heparinized krebs-henseleit solution containing 30 mmol/l 2,3 butanedionemonoxime (bdm, 4 degrees c, n = 3) or with heparinized pig blood (hpb, 24 degrees c, n = 3). after a three-hours storage period, magnetic res ... | 1998 | 9885120 |
| short report: identification of the likely etiologic agent of human trichinellosis in sicily (italy) between 1933 and 1946. | larvae of trichinella sp. collected in 1961 from muscle samples of the last infected domestic pig slaughtered in sicily (italy), and preserved in absolute ethyl alcohol until 1997, have been identified as trichinella spiralis by the polymerase chain reaction. this finding explains the severity of the clinical picture, resulting in death, and the high number of fatal cases (20 of 184, 11%) observed in three sicilian outbreaks between 1933 and 1945, caused by the consumption of sausages from pigs ... | 1998 | 9886198 |
| laparoscopic renal cryotherapy in swine: comparison of puncture cryotherapy preceded by arterial embolization and contact cryotherapy. | variable results of open, percutaneous, and laparoscopic cryosurgery of the kidney have been reported. minimally invasive approaches to lower-pole renal ablation were prospectively compared in swine: laparoscopic puncture cryoablation preceded by arterial embolization, laparoscopic contact cryosurgery, and arterial embolization alone. eighteen kidneys in nine domestic pigs were randomized to one of three treatment groups of six organs each: (1) puncture cryotherapy preceded by selective lower-po ... | 1998 | 9895264 |
| introducing fluorine-18 fluoromisonidazole positron emission tomography for the localisation and quantification of pig liver hypoxia. | fluorine-18 labelled fluoromisonidazole ([18f]fmiso) has been shown to accumulate in hypoxic tissue in inverse proportion to tissue oxygenation. in order to evaluate the potential of [18f]fmiso as a possible positron emission tomography (pet) tracer for imaging of liver tissue hypoxia, we measured the [18f]fmiso uptake in 13 domestic pigs using dynamic pet scanning. hypoxia was induced by segmental arterial hepatic occlusion. during the experimental procedure the fractional concentration of insp ... | 1999 | 9933343 |
| seroprevalence of trichinella infection in domestic swine based on the national animal health monitoring system's 1990 and 1995 swine surveys. | swine sera collected by the us department of agriculture's center for animal health monitoring during 1990 and 1995 was tested for antibodies to trichinella spiralis using an enzyme immunoassay. from a total of 3048 sera collected from lactating sows in 1990, five sera tested positive for a prevalence of 0.16%. from a total of 7987 sera collected from both finishing pigs and gestating sows in 1995, one serum was positive for a prevalence of 0.013%. responses to questionnaires administered at the ... | 1999 | 9950336 |
| adventitial angiogenesis early after coronary angioplasty : correlation with arterial remodeling. | the spatial correlation between arterial wall microvessels and the accumulation of atherosclerotic plaque is well documented. the role of these microvessels in the development of primary and restenotic lesions is not known. to investigate the effect of interventional procedures on arterial wall microvessels, we studied the adventitial microvascularity of porcine coronary arteries subjected to angioplasty. twenty-two juvenile domestic swine were subjected to single or repeated (double) balloon an ... | 1999 | 9974402 |
| trichinellosis in the united states, 1991-1996: declining but not gone. | since the u.s. public health service began recording statistics on trichinellosis in 1947, the number of cases reported by state health departments has decreased steadily. in the late 1940s, health departments reported an average of 400 cases and 10-15 deaths each year. from 1991 to 1996, the period covered in this report, three deaths in 230 cases were reported to the centers for disease control and prevention (an average of 38 cases per year), including 14 multiple case outbreaks from 31 state ... | 1999 | 9988325 |
| filtered versus unfiltered technetium sulfur colloid in lymphatic mapping: a significant variable in a pig model. | lymphatic mapping with sentinel node biopsy is becoming a standard diagnostic test for melanoma and is being extensively investigated for use with other soft tissue tumors. both filtered and unfiltered technetium sulfur colloid (tc 99) have been used for preoperative lymphoscintigraphy, as well as intraoperative lymphatic mapping, and it is not clear if one is preferable over the other. the purpose of this study was to compare these two preparations to determine whether the form of tc 99 used af ... | 1999 | 10030419 |
| the effect of wiping on skin resurfacing in a pig model using a high energy pulsed co2 laser system. | the impact of wiping in laser skin resurfacing has not been systematically studied. | 1999 | 10037508 |
| oral immunisation of swine with a classical swine fever vaccine (chinese strain) and transmission studies in rabbits and sheep. | seven experiments including a total of 47 pigs, 11 wild boars, 26 rabbits, 10 hares and 16 sheep were carried out to assess the efficacy, safety and transmission of the chinese vaccine strain of the classical swine fever virus (csfv) administrated by the oral route. within 3 weeks after oral vaccination, a clear seroconversion occurred in the pigs. six weeks after vaccination, vaccinated pigs were fully protected against a virulent challenge. the c-strain was not isolated from tonsils, spleen, l ... | 1999 | 10063532 |
| hepatic cryosurgery via minilaparotomy in a porcine model: an alternative to open cryosurgery. | cryosurgery of liver lesions is becoming increasingly accepted for the ablation of liver tumors. attempts at laparoscopic cryosurgery have been very limited and often need to be converted to open laparotomy due to the complexity of the procedure. | 1999 | 10064758 |
| sutureless small bowel anastomoses: experimental study in pigs. | to evaluate a new technique for experimental anastomosis with fibrin glue, and to compare the results with those of stapled and one-layer sutured anastomosis. | 1999 | 10069636 |