| alkaline metal oxoantimonates(iii), a3[sbo3] (a = k or cs). | the two title trialkaline trioxoantimonates(iii), tripotassium trioxoantimonate(iii), k(3)[sbo(3)], (i), and tricaesium trioxoantimonate(iii), cs(3)[sbo(3)], (ii), crystallize in the cubic na(3)[ass(3)] structure type in space group p2(1)3. the structures show discrete psi-tetrahedral [sbo(3)](3-) anions with c(3v) point-group symmetry. the sb-o distances are 1.923 (4) a in (i) and 1.928 (2) a in (ii), and the o-sb-o bond angles are 99.5 (2) degrees in (i) and 100.4 (1) degrees in (ii). | 2001 | 11600759 |
| [treatment of ass-associated polyposis (assap) with a cysteinyl leukotriene receptor antagonist - a prospective drug study on its antiinflammatory effects]. | in a high rate of cases with recurrent polyposis an association with ass-intolerance is detectable despite missing pulmonary symptoms. new examinations of a disturbed arachidonic acid metabolism lead to the development of new therapeutical options. treatment with leukotriene-receptor antogonists (lta) showed primarily good results in therapy of ass-associated asthma. | 2001 | 11602930 |
| [two letters to alexander numan by j.h. van opdorp, surgeon at arnemuiden (province of zealand)]. | the periodical, veeartsenijkundig magazijn, that numan had started in 1828 caught the attention of a surgeon in a small town in the neighbourhood of middelburg. in his two letters he tells about his experiences in animal healing, leaving it to numan which use he eventually might make of these observations. in the first letter (1829) he tells how he as a ship's doctor was shipwrecked in the indian ocean, and after being put ashore on a small island, had successfully performed an operation on an a ... | 2000 | 11625626 |
| endometritis in she donkeys in egypt. | the endometrial necropsies of 165 she donkeys were examined and the endometria were classified into four grades according to histological features (i, iia, iib, iii). category i was observed in 86 cases (52.12%) and diagnosed as normal endometria. category iia was observed in 18 cases (10.91%) and diagnosed as slight endometritis. category iib was observed in 28 cases (16.97%) and diagnosed as moderate endometritis (two to four nests/field), while category iii was observed in 33 cases (20%) and ... | 2001 | 11666035 |
| preparation and structures of the 2.2.2-cryptand(1+) salts of the [sb(2)se(4)](2)(-), [as(2)s(4)](2)(-), [as(10)s(3)](2)(-), and [as(4)se(6)](2)(-) anions. | 2.2.2-cryptand(1+) salts of the [sb(2)se(4)](2)(-), [as(2)s(4)](2)(-), [as(10)s(3)](2)(-), and [as(4)se(6)](2)(-) anions have been synthesized from the reduction of binary chalcogenide compounds by k in nh(3)(l) in the presence of the alkali-metal-encapsulating ligand 2.2.2-cryptand (4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane), followed by recrystallization from ch(3)cn. the [sb(2)se(4)](2)(-) anion, which has crystallographically imposed symmetry 2, consists of two discrete edge ... | 1996 | 11666829 |
| head-to-head linked double calix[4]arenes: convenient synthesis and complexation properties. | combination of calix[4]arenes functionalized at the upper rim at the 5- and 17-positions with amino and formyl groups, respectively, gives a new series of "head-to-head" linked double calix[4]arenes in nearly quantitative yield. the x-ray structure of a modified double calix[4]arene is reported. the novel, highly preorganized receptor molecules complex silver(i) ions (k(ass) = 9.5 x 10(5) m(-)(1) in cdcl(3)); the selectivity of complexation was studied by supported liquid membrane transport expe ... | 1997 | 11671587 |
| [botulin toxin as treatment for spasticity and dystonia in infantile cerebral paralysis]. | treatment of spasticity and dystonía in pci with botulinum toxin a. | 2001 | 11692809 |
| relationships between host species and morphometric patterns in fasciola hepatica adults and eggs from the northern bolivian altiplano hyperendemic region. | the highest prevalences and intensities of human fasciolosis by fasciola hepatica are found in the northern bolivian altiplano, where sheep and cattle are the main reservoir host species and pigs and donkeys the secondary ones. morphometric comparisons of many linear measurements, areas and ratios of f. hepatica adults (from sheep, cattle and pigs) and eggs (from sheep, cattle, pigs and donkeys) in natural liver fluke populations of the bolivian altiplano, as well as of f. hepatica adults and eg ... | 2001 | 11705655 |
| antisense anti-mdm2 oligonucleotides as a novel therapeutic approach to human breast cancer: in vitro and in vivo activities and mechanisms. | the mouse double minute 2 (mdm2) oncogene has been suggested as a target for cancer therapy. it is amplified or overexpressed in many human cancers, including breast cancer, and mdm2 levels are associated with poor prognosis of several human cancers, including breast cancer, ovarian cancer, osteosarcoma, and lymphoma. in the present study, we investigated the functions of mdm2 oncogene in the growth of breast cancer and the potential value of mdm2 as a drug target for cancer therapy by inhibitin ... | 2001 | 11705884 |
| computing the properties of the copper thioarsenite complex, cuass(sh)(oh). | in aqueous solutions in equilibrium with the mineral assemblage cus (covellite)-cu(1.8)s (digenite)-cu(3)ass(4) (enargite), a copper thioarsenite species, cuass(sh)(oh), makes major contributions to both cu and as solubility (clarke, m. b.; helz, g. r. environ. sci. technol. 2000, 34, 1477-1482. the structure and energetics of this complex have been calculated quantum mechanically (tossell, j. a. environ. sci. technol. 2000, 34, 1483-1488), confirming its high stability and establishing the pres ... | 2001 | 11720505 |
| cylicocyclus asini n. sp. (nematoda: cyathostominae) from donkeys equus asinus in south africa. | cylicocyclus asini n. sp. is described from the ventral colons of seven domesticated donkeys equus asinus in south africa. the specimens are smaller than 11 members of the genus cylicocyclus, which currently comprises 10 recognised species, one recognised subspecies and two species inquirendae, but is similar in size to the two smaller species, c. ashworthi and c. leptostomum. additionally, the small size of its buccal capsule places it within the so-called small buccal capsule group, namely c. ... | 2002 | 11721193 |
| the reluctant donkey. | | 2001 | 11725438 |
| the blood vasculature as the forming element of the uterus of the estrous donkey (equus asinus). | light, scanning electron microscopy of endometrial surface and vascular casts were used to study the vascular architecture of the donkey uterus during estrous. the arterial blood supply of the uterus comes from three arteries: the uterine branch of the ovarian artery, the uterine artery of the external iliac artery, and the uterine branch of the urogenital artery. all arteries enter the uterus at its mesometrial border and divide into smaller ones. segmentally constricted arteries are seen to ci ... | 2001 | 11732590 |
| identification and characterization of cis elements in the stat3 gene regulating stat3 alpha and stat3 beta messenger rna splicing. | signal transducer and activator of transcription 3 (stat3) is an oncogene and a critical regulator of multiple cell-fate decisions, including myeloid cell differentiation. two isoforms of stat3 have been identified: alpha (p92) and beta (p83). these differ structurally in their c-terminal transactivation domains, resulting in distinct functional activities. the cis genetic elements that regulate the ratio of alpha to beta messenger rna (mrna) are unknown. in this study, cloning, sequencing, and ... | 2001 | 11739197 |
| rift valley fever outbreak, mauritania, 1998: seroepidemiologic, virologic, entomologic, and zoologic investigations. | a rift valley fever outbreak occurred in mauritania in 1998. seroepidemiologic and virologic investigation showed active circulation of the rift valley fever virus, with 13 strains isolated, and 16% (range 1.5%-38%) immunoglobulin (ig) m-positivity in sera from 90 humans and 343 animals (sheep, goats, camels, cattle, and donkeys). one human case was fatal. | 2001 | 11747742 |
| [the beginnings and development of diagnostic imaging in nuclear medicine]. | introduction: the phenomenon of radioactivity was discovered in 1896 by antoin henri becquerel, but its application in visual diagnostics started about fifty years later. rectilinear scanner: it was constructed by b. cassen and ass. in 1949, when first scintiscans were obtained. technical improvements have been made 1950-1956 (b. cassen and ass., r. newall and ass., p. bell, d. kuhl). soon after appearance of the first cassen's scanner, commercial production began. gamma camera: it was invented ... | 2001 | 11759228 |
| animal genetic resources in brazil: result of five centuries of natural selection. | brazil has various species of domestic animals, which developed from breeds brought by the portuguese settlers soon after their discovery. for five centuries, these breeds have been subjected to natural selection in specific environments. today, they present characteristics adapted to the specific brazilian environmental conditions. these breeds developed in brazil are known as "crioulo," "local," or naturalized. from the beginning of the 20th century, some exotic breeds, selected in temperate r ... | 2002 | 11775972 |
| rbc storage for 11 weeks. | increasing the length of rbc storage can increase both rbc availability and quality. this work addresses 11-week rbc storage in experimental ass (eass). | 2001 | 11778076 |
| correspondence of human chromosomes 9, 12, 15, 16, 19 and 20 with donkey chromosomes refines homology between horse and donkey karyotypes. | whole chromosome paints for human (hsa) chromosomes 9, 12, 15 and 20 and arm-specific paints for hsa16p, 19p and 19q were applied on donkey metaphase spreads. all probes, except hsa19p, gave distinct hybridization signals on donkey chromosomes/chromosomal segments. the results show direct segmental homology between human and donkey genomes, and enable refinement of correspondence between donkey and horse karyotypes. of specific interest is the identification of hitherto unknown correspondence be ... | 2001 | 11778685 |
| [primary prevention of cardiovascular events by ass and vitamin e. ppp--primary prevention project]. | | 2001 | 11793610 |
| use of sterile maggots to treat panniculitis in an aged donkey. | an aged female donkey developed a severe, localised, suppurative panniculitis secondary to a skin wound. bacterial culture of swabs taken from the wound gave a profuse growth of multi-drug-resistant pseudomonas aeruginosa, a profuse growth of escherichia coli and a moderate growth of beta-haemolytic streptococcus species. the lesion did not respond to conventional medical and surgical treatment and continued to progress. six applications of sterile larvae (maggots) of the common greenbottle, luc ... | 2001 | 11808664 |
| the oxpa5 mutation of aspergillus nidulans is an allele of adb, the gene encoding adenylosuccinate synthetase. | the oxpa5 mutation in aspergillus nidulans results in a pleiotropic phenotype, including resistance to oxypurinol and partial constitutivity of the enzymes of purine catabolism. here we show that the oxpa5 mutation is an allele of adb, the gene encoding adenylosuccinate synthetase (ass). cloning, sequencing and characterisation of the adb gene are reported in this paper. in vivo complementation tests indicate that the oxpa5 mutation is a partial loss-of-function mutation, and altered kinetic par ... | 2001 | 11810243 |
| molecular determinants of the mechanism underlying acceleration of the interaction between antithrombin and factor xa by heparin pentasaccharide. | the control of coagulation enzymes by antithrombin is vital for maintenance of normal hemostasis. antithrombin requires the co-factor, heparin, to efficiently inhibit target proteinases. a specific pentasaccharide sequence (h5) in high affinity heparin induces a conformational change in antithrombin that is particularly important for factor xa (fxa) inhibition. thus, synthetic h5 accelerates the interaction between antithrombin and fxa 100-fold as compared with only 2-fold versus thrombin. we bu ... | 2002 | 11854268 |
| comparative fish mapping of 32 loci reveals new homologous regions between donkey and horse karyotypes. | a total of 32 loci comprising specific genes, microsatellites and anonymous bac clones from horse and cattle were mapped on donkey chromosomes. of these, 13 markers were also mapped for the first time in the horse. this information, together with that previously available in donkey and horse updates the comparative status of the karyotypes of the two species. the findings of the present study for the first time show correlation between eleven equine acrocentric autosomes and the donkey chromosom ... | 2001 | 11856877 |
| [deworming schedule in mixed group of horses and donkeys]. | | 2002 | 11858042 |
| analysis of the binding of bispecific monoclonal antibodies with immobilized antigens (human igg and horseradish peroxidase) using a resonant mirror biosensor. | the interaction between two monoclonal antibodies (mabs) and their corresponding bispecific antibody (bab) with immobilized antigens has been examined using a resonant mirror biosensor (iasys). babs were produced by cell fusion. the analysed panel of affinity-purified antibodies included two parental mabs, one specific to human igg (higg), and another specific to horseradish peroxidase (hrp), and a bab derived thereof (anti-higg/hrp). the real-time analysis showed the drastic differences in the ... | 2002 | 11861069 |
| [pharmacokinetics after oral and intravenous administration of d,l-monolysine acetylsalicylate and an oral dose of acetylsalicylic acid in healthy volunteers]. | we studied the asa pharmacokinetics of single doses of 500 mg and 1000 mg of d,l-lysine-monoacetylsalicylate (lys-asa) administered both orally (delgesic) and 500 mg parenterally (aspisol) as well as 500 mg acetylsalicylate (asa, aspirin) in 13 healthy volunteers. blood samples were taken before and at defined times up to 48 h after application of lys-asa and asa. analysis for asa and its metabolite salicylic acid were performed by hplc. all concentration versus time data were presented descript ... | 2001 | 11878089 |
| catecholase activity of a series of dicopper(ii) complexes with variable cu-oh(phenol) moieties. | the catecholase activity of a series of dicopper(ii) complexes containing different numbers of phenol groups coordinated to the metal centers was studied to identify functional as well as structural models for the type iii copper enzymes tyrosinase and catechol oxidase. the syntheses and characterization of complexes [cu(2)(h(2)bbppnol)(mu-oac)(h(2)o)(2)]cl(2).2h(2)o (1) and [cu(2)(hbtppnol)(mu-oac)](clo(4))(2) (2) were previously reported by us (inorg. chim. acta 1998, 281, 111-115; inorg. chem ... | 2002 | 11925171 |
| d-assirc: distributed program for finding sequence similarities in genomes. | locating the regions of similarity in a genome requires the availability of appropriate tools such as 'accelerated search for similar regions in chromosomes' (assirc; vincens et al., bioinformatics, 14, 715-725, 1998). the aim of this paper is to present different strategies for improving this program by distributing the operations and data to multiple processing units and to assess the efficiency of the different implementations in terms of running time as a function of the number of processing ... | 2002 | 11934744 |
| expression of neural cell adhesion molecule (ncam) in the peripheral nerve fibers demonstrated by postembedding immunogold method on ultrathin sections. a preliminary study. | the neural cell adhesion molecule, ncam, is thought to be necessary for the interaction between neurons, axons and glial cells, axons and target structures, and for myelination. the ncam localization in the peripheral nerves has been less well studied. the data have shown significant differences. in this study, the distribution of the ncam immunoreactivity in the sciatic nerves of 10- and 15-day-old wistar rats was examined on ultrathin sections by the immunogold postembedding method. the sectio ... | 2002 | 11936192 |
| structure of the human argininosuccinate synthetase gene and an improved system for molecular diagnostics in patients with classical and mild citrullinemia. | deficiency of argininosuccinate synthetase (ass) causes citrullinemia, an autosomal recessive inherited defect of the urea cycle. most patients described so far have presented with the classical form of the disease. there are also patients with a mild form of citrullinemia in whom the exact molecular basis and clinical relevance are uncertain. mutations in the human ass gene have not yet been described in mildly affected or asymptomatic patients with citrullinemia. the genomic sequence of the hu ... | 2002 | 11941481 |
| inducible nitric oxide synthase and argininosuccinate synthetase: co-induction in brain tissue of patients with alzheimer's dementia and following stimulation with beta-amyloid 1-42 in vitro. | in alzheimer's disease (ad), amyloid plaques within the brain are surrounded by activated glial cells (microglia and astrocytes). the mechanisms of glial activation and its effect on disease progression are not fully understood. growing evidence suggests that beta-amyloid (abeta) peptide, a major constituent of the amyloid plaque, is critically involved in the induction of an inflammatory response. the goal of this study was to examine the role of abeta in the pathogenesis of local inflammation ... | 2002 | 11958858 |
| common vetch (vicia sativa) for improving the nutrition of working equids in campesino systems on hill slopes in central mexico. | campesino systems on hill slopes in central mexico rely on equids for multiple activities and have a problem in adequately feeding them. a participatory trial was conducted to evaluate the inclusion of common vetch in the traditional forage oat crop to improve its feeding value. an agronomic evaluation was undertaken by intersowing common vetch at 40 kg seed/ha with oats at 80-100 kg/ha in small plots, recording the yield and the chemical composition of the fresh forage in ten plots at harvest. ... | 2002 | 11969114 |
| vaccination of donkeys against babesia equi using killed merozoite immunogen. | protective efficacy of a killed babesia equi immunogen was assessed in donkeys. the immunogen was prepared from b. equi infected blood so as to contain lysate of 2 x 10(10) parasitised erythrocytes per dose. the immunogen was mixed with an adjuvant quil a (3mg) and inoculated into four susceptible donkeys (group i). a booster inoculation was given after 21 days of first inoculation followed by challenge with fresh infected blood containing 1x10(11) parasitised erythrocytes 14 days later. two gro ... | 2002 | 11992708 |
| expression of three mitochondrial solute carriers, citrin, aralar1 and ornithine transporter, in relation to urea cycle in mice. | the present report describes the expression profiles of different tissues and developmental changes of mouse aspartate/glutamate carrier (agc) genes, slc25a13 and slc25a12, and an ornithine transporter gene, ornt1, in relation to urea cycle enzyme genes, carbamoylphosphate synthetase i (cps) and argininosuccinate synthetase (ass). slc25a13 encodes citrin, recently found to be deficient in adult-onset type ii citrullinemia and to function as agc together with its isoform and product of slc25a12, ... | 2002 | 11997094 |
| conservation of recognition of antibody and t-cell-defined alloantigens between species of equids. | serological and cellular assays and molecular techniques were used to define features of the major histocompatibility complex (mhc) of the donkey with this information in hand, immune recognition of mhc determinants within and between donkeys and horses was compared. an antibody-mediated, complement-dependent, microcytotoxicity assay using a variety of antisera to donkey histocompatibility antigens, including those induced as a result of intraspecies or interspecies pregnancy in horse mares and ... | 2001 | 11999315 |
| fibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts. | we examine the relationship between the chain length of heparin-derived oligosaccharides, fibroblast growth factor (fgf)-2 binding kinetics and the ability of the oligosaccharides to allow fgf-2-induced proliferation of chlorate-treated rat mammary fibroblasts. first, using an optical biosensor, we show that fgf-2 did not bind disaccharides, but definitively bound to tetrasaccharides. as the chain length increased from tetrasaccharide to octasaccharide, there was a substantial increase in k(ass) ... | 2002 | 12000311 |
| transmission patterns of african horse sickness and equine encephalosis viruses in south african donkeys. | african horse sickness (ahs) and equine encephalosis (ee) viruses are endemic to southern africa. ahs virus causes severe epidemics when introduced to naive equine populations, resulting in severe restrictions on the movement of equines between ahs-positive and negative countries. recent zoning of south africa has created an ahs-free zone to facilitate equine movement, but the transmission dynamics of these viruses are not fully understood. here, we present further analyses of serosurveys of don ... | 2002 | 12002545 |
| anaerobic digestion of alcohol sulfate (anionic surfactant) rich wastewater--batch experiments. part ii: influence of the hydrophobic chain length. | high-strength wastewater of some industries contains high concentrations of surfactants and readily biodegradable compounds like starch and other carbohydrates. wastewater of this type is found in the textile wet-processing industry (e.g., cotton desizing). the anaerobic degradation process in such wastewater is inhibited due to the high surfactant content. alcohol sulfate (as) of increasing hydrophobic chain length (c8 to c18, surfactant) and soluble starch (size) were used as model compounds i ... | 2002 | 12003312 |
| osteopontin regulates adhesion of calcium oxalate crystals to renal epithelial cells. | the association of calcium crystals with renal tubular cells is an important factor during the formation of urinary stones. we previously reported the strong expression of osteopontin (opn) on renal tubular cells in the stone-forming kidney, suggesting that opn plays a role in the crystal-cell interaction. in the present study, we examined the biological consequences of inhibiting opn expression at the translational level on the formation and adhesion of crystals. | 2002 | 12028300 |
| genetic diversity of three donkey populations in the croatian coastal region. | genetic variation in three croatian donkey populations, istrian (is), north adriatic (na) and littoral-dinaric (ld), was analysed using eight microsatellite loci and by sequence and sscp analysis of the proximal portion of the mtdna d-loop region. the analysis of microsatellite loci revealed observed heterozygosities in the range of 0.37 (mpz002 in ld) to 0.85 (aht21 in ld) and polymorphic information content values in the range of 0.36 (mpz002 in na) to 0.78 (aht21 in ld). the overall probabili ... | 2002 | 12030919 |
| relationship between mercury concentration in blood, cognitive performance, and blood pressure, in an elderly urban population. | concentration of mercury (hg) in whole blood in an elderly urban population with a mean age of 87 years was studied in relation to cognitive function, arterial blood pressure (arterial bp), age, gender, body mass index (bmi) and smoking habits. this population-based study consisted of 106 subjects both males and females. clinical assessment of the subjects included medical and social history, physical and neurologic examination and assessment of cognitive functions with mini-mental state examina ... | 2002 | 12046928 |
| a review on fascioliasis in egypt. | fascioliasis, caused by fasciola species, is a disease of herbivorous animals. it has a worldwide distribution in a large variety of grass-grazing animals as sheep, goats, cattle, buffaloes, horses and rabbits. in egypt, donkeys and camels as well, are hosts for f. gigantica. fascioliasis may occasionally affect man. human infection causes serious hepatic pathological sequences that add to the already known threats to the liver of the egyptian population. two clinical stages are recognized in hu ... | 2002 | 12049266 |
| effect of management interventions on the helminth parasites recovered from donkeys in south africa. | the helminth burdens and biodiversity of 9 randomly selected donkeys (equus asinus) were examined after necropsy. prior to necropsy, 8 of the animals were subjected to 1 of 3 management interventions (monthly fecal removal, prewinter moxidectin treatment, and a combination of both treatments) or a control for a 16-mo period. the remaining animal was killed earlier in the study. quantitative samples were collected from the gastrointestinal tract for helminth recovery. the intestinal walls were ex ... | 2002 | 12053959 |
| impact of management interventions on helminth levels, and body and blood measurements in working donkeys in south africa. | the aim of the study was to determine the effect of alternative management interventions on levels of nematodes and the condition of working donkeys in south africa. twenty-four adult donkeys (equus asinus) within an area of 200km radius were randomly allocated to eight paddocks. two replicates each of three management interventions together with a control group were tested in a 16-month study. the interventions included monthly removal of feces from paddocks where the donkeys grazed, a pre-wint ... | 2002 | 12072218 |
| l-citrulline recycle for synthesis of no in cerebral perivascular nerves and endothelial cells. | recycle of l-citrulline to form l-arginine in cerebral perivascular nerves has been well described, providing direct evidence that nitric oxide (no) is synthesized and released from these nerves to act as the transmitter for vasodilation. no is also synthesized and released from cerebral endothelial cells, involving l-citrulline conversion to l-arginine. evidence for the presence of enzymes involved in the conversion, however, has not been shown. the presence of nitric oxide synthase (nos), argi ... | 2002 | 12076964 |
| comparative testis morphometry and seminiferous epithelium cycle length in donkeys and mules. | the mule (equus mulus mulus) is a sterile hybrid domestic animal that results from the breeding of a male donkey (equus asinus) to a female horse (equus caballus). usually, spermatogenesis in mules does not advance beyond spermatocytes. in the present study, we performed a comparative and more accurate morphometric and functional investigation of the testis in donkeys and mules. due to the smaller testis size, lower seminiferous tubule volume density, and fewer germ cells, the total length of se ... | 2002 | 12080024 |
| [complicated antiphospholid antibody syndrome]. | a 51-year-old female patient suffered from recurrent ischemic strokes and venous thromboembolism although treated with ass and phenprocoumon, which mainly occurred after diagnosis and treatment of an invasive-ductal mamma carcinoma. the severely ill patient presented with right-sided hemiparesis and dysarthria, a swollen leg, a painful necrotic-ulcerative lesion at the left-lateral ankle and a systolic heart murmur. | 2002 | 12098096 |
| controlling lewis basicity in polythioarsenate fluxes: stabilization of ksnass(5) and k(2)snas(2)s(6). extended chains and slabs based on pyramidal beta-[ass(4)](3-) and [ass(3)](3-) units. | two low-dimensional compounds, ksnass(5) and k(2)snas(2)s(6), were prepared using liquid polythioarsenate salts, and the results differ from those obtained with the well studied thiophosphate flux. ksnass(5) crystallizes in the orthorhombic space group pbam with cell parameters of a = 8.136(2) a, b = 13.784(4) a, c = 7.428(2) a. ksnass(5) features the unusual pyramidal species [ass(2)(s(2))](3-). k(2)snas(2)s(6) crystallizes in the trigonal space group p3 macro with cell parameters a = 6.717(5) ... | 2002 | 12099862 |
| somatosensory discrimination of shape: tactile exploration and cerebral activation. | this study of somatosensory discrimination of rectangular parallelepipeda with the right hand had three purposes: (i) to describe the exploratory finger movements; (ii) to reveal the anatomical brain structures specifically engaged in the production of exploratory finger movements; and (iii) to reveal the anatomical structures specifically engaged in the discrimination of tactually sensed shape. the thumb was the most active finger, moving with a mean exploration frequency of 2.4 hz, as evident ... | 1991 | 12106480 |
| improving the prenatal diagnosis of citrullinemia using citrulline/ornithine+arginine ratio in amniotic fluid. | prenatal diagnosis of citrullinemia is performed using a direct argininosuccinate synthetase (ass) assay on chorionic villi (cv) and citrulline concentration measurement in early amniotic fluid (af). here we report the results of 40 prenatal diagnoses performed using this method, discuss the difficulties encountered in interpreting the results, and propose the use of the citrulline/ornithine+arginine ratio (which is more discriminatory than citrulline concentration alone) when performing prenata ... | 2002 | 12116302 |
| use of a biosensor to determine the binding kinetics of five lectins for galactosyl-n-acetylgalactosamine. | the dietary lectins, edible mushroom (abl) and jacalin (jac) inhibit the proliferation of colonic cancer cells, whereas amaranth (acl) and peanut (pna) stimulate their proliferation. all these lectins share as their preferred ligand the thomsen-friedenreich (tf) antigen galactosyl beta1,3 n-acetylgalactosamine (galbeta1,3galnac), but differ in their finer specificities for modifications of this determinant and in their specificities for cancerous epithelia. we have investigated, using a resonant ... | 2001 | 12151718 |
| association of two newly recognized herpesviruses with interstitial pneumonia in donkeys (equus asinus). | over a period of 6 years, antemortem and postmortem examinations were performed on a number of donkeys suffering from respiratory disease. for many cases, initial diagnostic efforts failed to identify an etiology consistent with the pathologic findings. however, retrospective examination of these cases using consensus primer polymerase chain reaction, designed to recognize herpesviruses from all 3 subfamilies of the herpesviridae, amplified a fragment of the highly conserved herpesvirus dna poly ... | 2002 | 12152805 |
| identification of immunoreactive polypeptides of babesia equi parasite during immunization. | this study was carried out to identify immunoreactive polypeptides in babesia equi merozoite antigen. three fractions of killed b. equi merozoite antigen viz.; whole merozoite (wm), cell membrane (cm) and high speed supernatant (hss) antigens were prepared from the parasite infected erythrocytes. these antigenic preparations along with ghost antigen from non-infected erythrocytes were fractionated on 12% sodium dodecyl sulphate-polyacrylamide gel electrophoresis (sds-page) and immunoblotted with ... | 2002 | 12163241 |
| [glanders--a potential disease for biological warfare in humans and animals]. | infection with burkholderia mallei (formerly pseudomonas mallei) can cause a subcutaneous infection known as "farcy" or can disseminate to condition known as glanders. it is primarily a disease affecting horses, donkeys and mules. in humans, glanders can produce four types of disease: localized form, pulmonary form, septicemia, and chronic form. necrosis of the tracheobronchial tree and pustular skin lesions characterize acute infection with b. mallei. other symptoms include febrile pneumonia, i ... | 2002 | 12170562 |
| the novel serpin endopin 2 demonstrates cross-class inhibition of papain and elastase: localization of endopin 2 to regulated secretory vesicles of neuroendocrine chromaffin cells. | this study demonstrates that endopin 2 is a unique secretory vesicle serpin that displays cross-class inhibition of cysteine and serine proteases, indicated by effective inhibition of papain and elastase, respectively. homology of the reactive site loop (rsl) domain of endopin 2, notably at p1-p1' residues, with other serpins that inhibit cysteine and serine proteases predicted that endopin 2 may inhibit similar proteases. recombinant n-his-tagged endopin 2 inhibited papain and elastase with sec ... | 2002 | 12173926 |
| [housing and use of horses in switzerland: a representative analysis of the status quo]. | out of a representative sample of 1861 swiss horse yards, 622 horse keepers (35.2%) with 2536 horses, ponies and donkeys sent back a questionnaire about general farm characteristics, their horse-specific training, horse stock, housing conditions, intraspecific social contacts, feeding, ability to move freely, use of the horses and management. 83.5% of horses were kept individually (thereof 18.3% tethered, 32.3% in a loose box indoors, 28.4% in a loose box outdoors, and 4.5% in a loose box with p ... | 2002 | 12174681 |
| speech and language skills and cognitive functioning in children with apert syndrome: a pilot study. | there are few studies that report findings on the speech and language characteristics of apert syndrome and little is known about the cognitive profile of the syndrome. the current study addresses this gap and explores speech, language, resonance/voice, attention oro-motor and cognitive skills in a group of 10 children (4;1-5;11) with apert syndrome. the speech and language battery included: the celf-pre-school, the pls-3, the vocal profile analysis, gos.sp.ass, pacs; and the brodsky drooling sc ... | 2002 | 12201981 |
| the anatomy of the energetics of molecular recognition by calorimetry: chiral discrimination of camphor by alpha-cyclodextrin. | the molecular recognition of both camphor enantiomers 2 with the chiral alpha-cyclodextrin (alpha-cd) 1 in water and d(2)o was examined by calorimetry. on the basis of statistically supported determinations the thermodynamics of 2:1 host-guest binding and chiral discrimination was evaluated. the energetic signature strongly supports hydrophobic interaction as the dominant driving force for camphor encapsulation by alpha-cd in water. the solvent isotope effect on the binding equilibrium served to ... | 2002 | 12203332 |
| hierarchical analysis of genetic structure in spanish donkey breeds using microsatellite markers. | the hierarchical population structure of five, native-spanish donkey breeds (andaluza, catalana, mallorquina, encartaciones and zamorano-leonesa) has been studied using f-statistics. in addition, nine moroccan asses and 24 merens breed horses were included in the analysis. data came from 15 dna microsatellites. the analysis shows that spanish donkeys are substructured at both hierarchical levels studied, among breeds and within breeds (between subpopulations). in the whole population, the defici ... | 2002 | 12209391 |
| protamine p1 sequences in equids: comparison with even-toed animals. | protamine p1 amino acid sequences were determined from semen samples of the przewalski horse, donkey, somali wild ass, grevy's zebra, and grant's zebra (odd-toed perissodactyls), and compared with those of the domestic horse. although the rate of amino acid variation of protamine p1 is known to be among the most rapidly diverging polypeptides, the equid sequences revealed only little variation. the sequence from the przewalski horse was identical with that from the domestic horse. the other sequ ... | 2002 | 12212882 |
| from counting neurons to the preclinical diagnosis of alzheimer's disease. | this article is a review of scientific work on alzheimer neurofibrillary degeneration and ass-amyloidosis that was done in collaboration with dr. henryk wisniewski, in part at the institute for basic research in developmental disabilities. our work on paired helical filaments and the tau protein spans from basic immunocytochemical analyses of brain tissue to clinical application as a biological marker used in diagnostic tests. even though only a small part of dr. wisniewski's scientific oeuvre, ... | 2001 | 12214073 |
| elevated levels of tau in cerebrospinal fluid: implications for the antemortem diagnosis of alzheimer's disease elevated levels of tau in cerebrospinal fluid: implications for the antemortem diagnosis of alzheimer's disease. | alzheimer's disease (ad) is a heterogeneous group of dementias characterized by progressive cognitive impairments as well as by the accumulation of abundant extracellular deposits of ass and intra-neuronal neurofibrillary lesions in selective-ly vulnerable regions of the ad brain. the latter abnormalities (e.g. neurofibrillary tangles, dystrophic neurites, neuropil threads) are aggregates of paired helical filaments (phfs) formed from altered tau proteins (phftau). although phf tau and normal ce ... | 1999 | 12214127 |
| the potential reservoir role of donkeys and horses in zoonotic fascioliasis in gharbia governorate, egypt. | no doubt, fascioliasis tops all the zoonotic helminthes worldwide. in egypt, human fascioliasis is increasing. the incidence and prevalence of fascioliasis in the egyptian farm animals are well documented. however, none in egypt has focused on the potential role of other domestic farm animals. a preliminary coprologic examination of donkeys and horses was done in eight centers of gharbia governorate. the overall rate of infection in donkeys was 3.03%, in horses was 1.5%, and in mules 0.0%. horse ... | 2002 | 12214933 |
| [microsatellite analysis in a population of baudet du poitou donkeys]. | a population of baudet du poitou donkeys was genetically characterized using microsatellites. the results were used to verify the pedigrees and to estimate the genetic variability. it could be confirmed that a equine parentage test kit works well for donkeys and that by using 13 microsatellites more than 99% of wrong pedigree informations would be detected. the genetic variability was comparable to a representative group of baudet du poitou donkeys in france. | 2002 | 12224447 |
| ebr-1, a novel ambler subclass b1 beta-lactamase from empedobacter brevis. | empedobacter brevis (formerly designated flavobacterium breve) is a gram-negative aerobe involved in nosocomial infections. the ambler class b beta-lactamase gene bla(ebr-1) was cloned and expressed in escherichia coli from e. brevis clinical strain ass-1, which had reduced susceptibility to expanded-spectrum cephalosporins and carbapenems. purified beta-lactamase ebr-1 hydrolyzed penicillins, cephalosporins, and carbapenems efficiently but not aztreonam. kinetic parameters of ebr-1 were similar ... | 2002 | 12234848 |
| endemic existence of rabies in ethiopia. | the study on the prevalence of rabies was conducted on a retrospective data gathered from ehnri rabies diagnostic laboratory addis ababa, in the years 1979-1987. during this period a total of 8036 animals were brought to the rabies diagnostic laboratory. ninety one percent (7329) of these animals were dogs. the remaining 8.8% (707) comprised of cats, domestic animals (donkeys, cows, sheep) and wild animals (monkeys, jackals and hyenas). out of 7329 dogs examined 832 were positive for rabies. dog ... | 2002 | 12240578 |
| [willow bark extract--effects and effectiveness. status of current knowledge regarding pharmacology, toxicology and clinical aspects]. | new pharmacological and clinical studies show that standardized willow bark extracts (wre) is not only the natural form of salicylic acid. willow bark extract has comparable antiinflammatory activities as higher doses of acetylsalicylic acid (ass), and it shows antinociceptive and antipyretic activities. under the pharmacologically active doses, no adverse effects regarding the stomach mucosa was observed, in contrast to acetylsalicylic acid. a daily dose of 1572 mg willow bark extract of a prop ... | 2002 | 12244878 |
| the butajira rural health project in ethiopia: mothers' perceptions and practices in the care of children with acute respiratory infections. | in ethiopia, a social anthropologist, a pediatrician, and a nurse project supervisor interviewed 15 mothers living in butajira district to learn about their current perceptions and practices in the care of children with acute respiratory infections (aris) in order to plan effective intervention programs for the butajira rural health project. all the mothers were familiar with measles and identified fever and rash as its major symptoms. since they tended to believe that modern medication keeps ... | 1994 | 12320383 |
| the use of donkeys in the mexican central highlands: a gender perspective. | this study analyzes the use of donkeys in san pablo tlachichilpan, mexico from a gender perspective. information was gathered through survey, participatory rural appraisal methods, and direct observation. the results showed that the donkeys were used exclusively for carrying loads. they usually carry water, laundry, firewood, sand, soil, manure, a plough and maize stover, and the harvest. there were no preferences cited for using either the male or female donkey, as both have their own ... | 1999 | 12349291 |
| breakpoint characterization of der(9) deletions in chronic myeloid leukemia patients. | deletions adjacent to the 9/22 translocation breakpoint on the derivative chromosome 9 have recently been described in a substantial number of chronic myeloid leukemia (cml) cases, but their extension has not been characterized in detail. using fish with an appropriate set of bac/pac probes, we have characterized the deletion in 10 cml cases, identified by screening 71 patients at diagnosis. five patients showed a complex chromosome rearrangement and 3 of them were deleted. the size of the delet ... | 2002 | 12353269 |
| therapy of sneddon syndrome. | we report the case of a young woman with progressive cognitive decline and epilepsy. she showed ischemic cerebrovascular disease and proximal livedo racemosa. antiphospholipid antibody (apl) could not be detected and there were no microemboli on continuous transcranial doppler ultrasonography monitoring. histology of cerebral vessels showed intimal hyperplasia in small leptomeningeal venous vessels and micronecrosis of grey and white matter. we subsequently made the diagnosis of apl-negative sne ... | 2002 | 12373028 |
| three-dimensional visualization of connexin 43 on the human cardiomyocytes. | gap junctions created by a family of connexin proteins play an important role in the development of human heart. it has been previously shown that the abnormalities of right ventricular outflow tract are related to an altered level of expression of connexin 43. the right ventricular outflow tract narrowing, stenosis, or atresia of the main pulmonary artery and hypertrophy of the right ventricle are observed in tetralogy of fallot. the aim of the current study was to determine the distribution of ... | 2002 | 12373152 |
| facial injuries caused by animals in northern nigeria. | we did a retrospective survey of 34 patients who sustained facial injuries after animal associated incidents and presented to three nigerian teaching hospitals. there were 27 male (79%) and 7 female patients, whose ages ranged from 6 to 40 years. sixteen (47%) were less than 15 years. cows (n=14), camels (n=9), and donkeys (n=6) were the most commonly involved. three dog bites were seen. knocks from cows' horns (n=9) were the predominant mechanism of injury, followed by falls (n=8) and kicks (n= ... | 2002 | 12379192 |
| morphological characteristics of the tongue and its papillae in the donkey (equus asinus): a light and scanning electron microscopical study. | the morphology of the donkey tongue and its papillae were investigated by macroscopy and by light and scanning electron microscopy in ten adult animals (six males and four females). the spatula-shaped tongues measured about 28 cm in length, 4.5 cm in breadth and 3.5 cm in thickness. samples from different areas of four tongues were grossly examined and pieces were processed for light and scanning electron microscopy. filiform papillae were distributed mainly on the dorsum of the tongue, being th ... | 2002 | 12392327 |
| human cerebrospinal fluid apolipoprotein e isoforms are apparently inefficient at complexing with synthetic alzheimer's amyloid-[beta] peptide (a[beta] 1-40 ) in vitro. | variation at the apolipoprotein e locus on chromosome 19 plays a role in more cases of alzheimer's disease than does any other identified genetic determinant. we have previously reported the isoform-specific interaction of native human apolipoprotein e (apoe, gene; apoe, protein) epsilon 3 with the amyloid-ss peptide, ass(1-40), the major component of the cerebral amyloid deposits that appear to cause alzheimer's disease. | 2002 | 12393935 |
| urea cycle disorders in thai infants: a report of 5 cases. | urea cycle disorders (ucd) is an inborn error of urea synthesis in which ammonium and other nitrogenous precursors of urea accumulate leading to episodic coma and a high mortality rate. therapy with peritoneal dialysis, essential amino acids or their nitrogen-free analogues has increased survival. the authors report 5 cases of urea cycle disorders, all of whom developed and were rescued from hyperammonemic coma. however, the eventual outcome was quite variable. argininosuccinate lyase deficiency ... | 2002 | 12403252 |
| tolerance and hormesis--increased resistance to copper in hydroids linked to hormesis. | cultured clones of the colonial hydroid laomedeaflexuosa have been used over some years as an experimental model to study the dynamics of growth control [j. mar. biol. ass. uk (1981a) 61, 35; aquatic toxicology (1981b) 1, 227; journal of applied toxicology (2000a) 20, 93]. exposure to toxic agents has been an essential element of the approach, providing the stimulus to elicit adaptive control system responses. while the work has provided interpretations of physiological interest, it has also giv ... | 2002 | 12408654 |
| [secondary and primary prevention of coronary heart disease: platelet aggregation inhibitors and anticoagulants]. | this review presents the results of primary and secondary prevention of coronary heart disease (chd) with antiplatelet drugs and anticoagulants; therapeutic recommendations are derived. according to the results of the trials and due to its low price aspirin (ass) can be still considered as the drug of choice. its protective action has been documented for secondary prevention in patients with previous myocardial infarction, coronary angioplasty (pci), unstable and stable angina, but not in patien ... | 2002 | 12436764 |
| comparative mapping in equids: the asine x chromosome is rearranged compared to horse and hartmann's mountain zebra. | the x chromosomes of the extant equids, in general, share morphology and banding pattern similarities. however, the donkey x is, in part, an exception because of significantly different centromeric index and variant banding patterns in the pericentromeric region. to verify the underlying molecular basis of this difference, twelve equine bac clones were fish mapped to donkey (eas) and hartmann's mountain zebra (ezh) metaphase spreads. loci from the terminal region of xp and distal to terminal reg ... | 2002 | 12438800 |
| streptomyces sp., a cause of fistulous withers in donkeys. | four of 10 donkeys, which showed lesions simulating fistulous withers, were examined clinically with the aim to cultivate and identify the causal agent. aspiated purulent materials were subjected to bacteriological examination. the causal organisms were recovered in tryptic soya agar medium when incubated aerobically at 37 degrees c for up to 5 days. these organisms were found to be actinomycetes-like, gam positive with stable branching filaments and to form heavy aerial hyphae on colony surface ... | 2002 | 12448975 |
| [detection report on noxious elements in radix astragli]. | the contents and dissolution rates of as, hg, cd and pb including 44 batches of astragali samples from major habitats were analysed. | 2002 | 12451970 |
| thermodynamics of peptide binding to the transporter associated with antigen processing (tap). | the atp-binding cassette (abc) transporter tap plays an essential role in antigen processing and immune response to infected or malignant cells. tap translocates proteasomal degradation products from the cytosol into the endoplasmic reticulum, where mhc class i molecules are loaded with these peptides. kinetically stable peptide-mhc complexes are transported to the cell surface for inspection by cytotoxic t lymphocytes. the transport cycle of tap is initiated by peptide binding, which is respons ... | 2002 | 12470952 |
| cross-reactivity between mammalian proteins. | cross-reactivity between food allergens occurs when they share part of their amino acid sequence, or when their three-dimensional molecular structure causes them to have a similar capacity to bind specific antibodies. | 2002 | 12487198 |
| soy formulas and nonbovine milk. | cow's milk allergy is frequently observed during the first year of life when nutritional requirements are critical. in those cases where breast-feeding is not available, a safe and adequate substitute to cow's milk should be offered. | 2002 | 12487214 |
| the law is an ass. | | 2002 | 12506579 |
| [role of prostate fossa ultrasonography in the diagnosis of local recurrence after radical prostatectomy in case of psa failure]. | the aim of this study is to verify the diagnostic accuracy of transrectal ultrasound (trus) of vesico-urethral anastomosis in patients with psa elevation (> or = 0.2 ng/ml) after radical prostatectomy, who received 4-6 random anastomotic biopsies of the prostatic fossa plus additional biopsies directed to trus detectable lesions. | 2002 | 12508759 |
| application of mutation analysis for the previously uncertain cases of adult-onset type ii citrullinemia (ctln2) and their clinical profiles. | type ii citrullinemia (ctln2) is characterized by a deficiency of argininosuccinate synthetase (ass) in the liver. mutation analysis of the slc25a13 gene, which is responsible for ctln2, provides a rapid and accurate diagnosis. we describe clinical, biochemical and histologic features of two patients, whose diagnosis was finally made by mutation analysis. they initially presented with symptoms related to hyperammonemia at 16 to 22 years of age. a patient had shown mental retardation and growth f ... | 2002 | 12512993 |
| [flow cytometry combined assay for phosphatidylserine and cd62p expressed by preserved platelets]. | human platelets have distinct characters when preserved by different methods. a efficient flow cytometric assay for different preserved platelets expression of cd62p and phosphatidylserine(ps) is in dire need. efficient flow cytometric assay for cd62p and ps expressed by preserved platelets was established and the major conditions were optimized. the platelets need not to be washed to wipe off plasma and can be labelled diredtly during the sample preparation. it is efficient for flow cytometric ... | 2002 | 12513841 |
| splenectomy versus conservative management for acute sequestration crises in people with sickle cell disease. | acute splenic sequestration crises are a complication of sickle cell disease, with high mortality rates and frequent recurrence in survivors of first attacks. splenectomy and blood transfusion, with their consequences, are the mainstay of long term management used in different parts of the world. | 2002 | 12519596 |
| characterization of the beta2-microglobulin gene of the horse. | a clone containing beta(2)-microglobulin (beta(2)-m), the light chain of the major histocompatibility complex class i cell surface molecule, was isolated from an equine bacterial artificial chromosome library. this clone was used as a template for polymerase chain reaction (pcr) and unidirectional sequencing to elucidate the genomic sequence and intron/exon boundaries. we obtained 7,000 bases of sequence, extending from 1,100 nucleotides (nt) upstream of the coding region start through 1,698 nt ... | 2003 | 12557059 |
| fairness and health care decision making: testing the group value model of procedural justice. | considerable research has supported the notion that procedural justice is important to individuals independent of outcome considerations. tyler and his associates (lind and tyler, 1988; lind and earley 1992; tyler, 1989) proposed that this is so because procedural justice serves a group value function. in the present research, we explore aspects of this group value formulation in a real life health care context. specifically, we assessed the relationship between individuals' appraisals of proced ... | 1999 | 12564443 |
| oleander toxicosis in a donkey. | | 2003 | 12564736 |
| relationship of the livestock trade to schistosomiasis transmission in mountainous area. | to study the relationship between the livestock trade and schistosomiasis transmission and to provide an evidence for making a strategy of schistosomiasis control in mountainous areas. | 2000 | 12567688 |
| [the analysis of donkey-hide glue, antler glue and tortoise shell glue by means of circular dichroism]. | donkey-hide glue, antler glue, tortoise shell glue and their forgeries were identified by the analysis method of circular dichroism(cd) in this paper. the standard spectra and data were set up. the method is simple, fast and accurate. | 1998 | 12567974 |
| [variations of the celiac trunk branches in the fetus]. | the study was performed on 60 human foetuses, aged between 4 to 9 months, using as methods dissection and plastic and contrast substances injection. we studied the celiac trunk in what concerns the division into its terminal branches, insisting on the possible morphological variations, some rare collateral branches starting from the common arterial trunk, the dimensional relations between the branches at their origin and the level of the celiac trunk origin from the aorta, in relation with the v ... | 2002 | 12572348 |
| lateral mobility and specific binding to gaba(a) receptors on hippocampal neurons monitored by fluorescence correlation spectroscopy. | the binding behavior of a fluorescently labeled muscimol derivative to the gaba(a) receptor was analyzed at rat hippocampal neurons by fluorescence correlation spectroscopy. after muscimol had been labeled with the fluorophore alexa fluor 532, specific binding constants for binding of the dye-labeled ligand (mu-alexa) to the gaba(a) receptor were determined. we found a high specific binding affinity of mu-alexa with a k(d) value of 3.4 +/- 0.5 nm and a rate constant of ligand-receptor dissociati ... | 2003 | 12578381 |
| standardisation and comparison of serial dilution and single dilution enzyme linked immunosorbent assay (elisa) using different antigenic preparations of the babesia (theileria) equi parasite. | serial dilution and single dilution enzyme linked immunosorbent assays (elisa) were standardised and their sensitivity and specificity were compared for serodiagnosis of babesia equi infection. the antibody titres of 24 donkey sera of known identity were determined separately by serial dilution elisa using three different b. equi antigens namely whole merozoite (wm), cell membrane (cm) and high speed supernatant (hss). the ratios of the optical density (od) of known positive and known negative s ... | 2003 | 12588685 |
| analysis of bispecific monoclonal antibody binding to immobilized antigens using an optical biosensor. | the interaction between two different monoclonal antibodies (mabs) and their corresponding bispecific antibodies (babs) with immobilized antigens was investigated using an optical biosensor (iasys). the analyzed panel of affinity-purified antibodies included two parental mabs (one of which was specific to human igg (higg), and another one to horseradish peroxidase (hrp)), as well as babs derived thereof (anti-higg/hrp). babs resulting from the fusion of parental hybridomas bear two antigen-bindi ... | 2002 | 12600264 |
| study of antiproteinase activity of acylated derivatives of bowman-birk soybean proteinase inhibitor. | the effect of acylation of bowman-birk soybean proteinase inhibitor (bbi) by derivatives of various unsaturated fatty acids on inhibition of trypsin, alpha-chymotrypsin, and human leukocyte elastase was investigated. inhibition (k(i)) and kinetic (k(ass), k(diss)) constants of interaction between proteases and acylated bbi derivatives were determined. for mono-, di-, and triacylated bbi derivatives, insertion of two oleic residues into the bbi molecule was demonstrated to be more potent for exhi ... | 2002 | 12600268 |