| predictive structure-activity relationships in a series of pyranoquinoline derivatives. a new primate model for the identification of antiallergic activity. | a new primate model has been developed for the evaluation of antiallergic agents. compounds are tested for their ability to inhibit anti-ige induced histamine release from the bronchoalveolar mast cells lavaged from the lungs of macaca arctoides infected with the parasite ascaris suum. a number of 6-substituted pyranoquinoline derivatives have been evaluated and the activities were subjected to hansch analysis. a highly significant correlation with lipophilicity (pi) and hammett sigma p values w ... | 1988 | 2455052 |
| in vitro synthesis and processing of components of the ascaris suum pyruvate dehydrogenase complex. | poly(a)+ rna was isolated from ascaris suum body wall muscle and translated in a cell-free rabbit reticulocyte lysate system. specific antisera and immunoglobulins against the alpha-pyruvate dehydrogenase and dihydrolipoyl transacetylase components of ascarid pyruvate dehydrogenase complex were used to immunoprecipitate individual radiolabelled polypeptides from the in vitro translation mixtures. both polypeptides appeared to be synthesized as preproteins about 1.5 and 8 kda larger than the corr ... | 1988 | 2455226 |
| ascaris lumbricoides: zonal localization of immunoreactive collagen in the cuticle. | monoclonal antibodies that were raised against cuticular components from the free-living nematode panagrellus silusiae were found to react with a cuticular collagenous domain from ascaris lumbricoides. one of these monoclonal antibodies was used to localize the collagenous epitope within sectioned ascaris cuticles. by indirect immunofluorescence, accessible binding sites were observed in the basal zone of the cuticle. immunological staining occurred in the innermost lamella of the basal zone, i. ... | 1988 | 2456222 |
| examination of tissue for parasites by fluorescent microscopy. | | 1988 | 2456262 |
| [histochemical studies of the ova of ascaris suum during embryogenesis. i. phosphatases]. | | 1987 | 2457282 |
| [histochemical studies of the ova of ascaris suum during embryogenesis. ii. lipids and respiratory enzymes]. | | 1987 | 2457283 |
| characterization of isolated porcine intestinal mucosal mast cells following infection with ascaris suum. | porcine intestinal mucosal mast cells (immc) were isolated from intestinal tissues of swine by enzymatic digestion and density gradient separation. helminth-free swine and swine exposed to the nematode parasite, ascaris suum, were used as a source of intestinal tissue. up to 40% of the isolated intestinal cells stained metachromatically with toluidine blue ph 3.0, indicating the presence of immc. the histamine content of this cell population ranged from 2.9-8.9 pg per toluidine blue-positive imm ... | 1988 | 2462304 |
| effect of beta-adrenergic blockade and sympathetic stimulation on canine bronchial mast cell response to immune degranulation in vivo. | we examined the effect of beta-adrenoceptor blockade and residual alpha-adrenoceptor effects during sympathetic stimulation on mast cell secretion of histamine in 12 natively allergic mongrel dogs. bronchial mast cell response was measured as the arteriovenous difference (avd) in plasma histamine concentration [h] across the bronchus. plasma [h] was determined simultaneously from the azygos outflow tract and femoral artery as a marker of mast cell response prior to and for 90 s after intra-arter ... | 1989 | 2463779 |
| ascaris suum ova-induced bronchoconstriction, eosinophilia, and ige antibody responses in experimentally infected primates did not lead to histamine hyperreactivity. | the hypothesis that active immunization of primates to give airway allergic responses would also confer on them a hyperreactivity to a nonspecific stimulus such as histamine was tested in 29 normal rhesus primates. at 6 wk after immunization, specific primate ige (rast) to ascaris antigen had increased from 0.35 +/- 0.17 to 0.98 +/- 0.35 units/ml x 10(2) (p less than 0.05). histamine released from bronchial alveolar lavage cells in response to antigen increased from 5.4 +/- 0.67 to 24 +/- 1.8ng/ ... | 1989 | 2466426 |
| leukotriene c4 and b4 in bronchoalveolar lavage fluid during biphasic allergic bronchoconstriction in sheep. | to study the contribution of leukotriene c4 (ltc4), leukotriene d4 (ltd4), leukotriene b4 (ltb4), and inflammation to the antigen-induced late bronchial response, these leukotrienes, histamine, and cell differentials were evaluated in bronchoalveolar lavage fluid (balf). immediate and late responses were induced by ascaris suum antigen inhalation in 11 conscious sheep. bronchoalveolar lavage was performed on 3 separate test days, before challenge (control), during the immediate response, and dur ... | 1989 | 2466428 |
| antigenic relationships between the surface-exposed, secreted and somatic materials of the nematode parasites ascaris lumbricoides, ascaris suum, and toxocara canis. | the cosmopolitan nematode parasites ascaris lumbricoides, ascaris suum, and toxocara canis are closely related phylogenetically, and are all pathogenic to man. in the case of the latter, the antigens released by the tissue-invasive parasitic larvae in vitro ('excretory/secretory' or 'es' antigens) are routinely used for serodiagnostic purposes. here we have found, using radioimmunoprecipitation with defined rabbit antiserum, and sds-page, that there is a significant antigenic similarity between ... | 1989 | 2467777 |
| chronological relationships between mediator release and changes in airway dynamics during an ascaris response in sensitive cynomolgus monkeys. | recently identified ascaris suum sensitive cynomolgus monkeys were further characterized to determine if a chronologic relationship existed between mediator release and onset of bronchoconstriction. in these anesthetized ascaris-sensitive monkeys, aerosol antigen challenge of each animal produced rapid and severe bronchoconstriction, as determined by decreases in dynamic lung compliance (-80.2 +/- 4.1%) and airway conductance (-64.5 +/- 13.8%). maximum changes were achieved within 5 min followin ... | 1989 | 2470112 |
| [histopathologic and cytochemical studies of the kidneys of guinea pigs infected with larvae of ascaris suum goeze, 1782]. | the material consisted of 20 male guinea pigs of body weight 300 +/- 50 g. fifteen of them were infected per os with a dose of 5000 invasive eggs of a. suum. at the 4th, 7th and 20th days of infection the animals were dissected and sections of kidney were taken for histopathological and histochemical studies. the sections were stained with hematoxylin and eosin. the presence of mucopolisachcarides was detected with the pas method, the activity of acid and alkaline phosphatases--with gomori's met ... | 1989 | 2470207 |
| transcription in nematodes: early ascaris embryos are transcriptionally active. | in this report we analyze early zygotic gene expression in the parasitic nematode ascaris lumbricoides var. suum. using synchronous populations of early embryonic stages, nuclei were isolated, and in vitro run-off transcription assays were performed. we find transcriptional activity as early as the 4- to 8-cell stage. the percentage of rna polymerase ii activity, as measured in these assays, is greater than 80% of the total transcription at the 60-cell stage. furthermore, we show that a specific ... | 1989 | 2471658 |
| [studies on monoclonal antibodies directed against human c-peptide]. | by comparison, it was shown that ascaris protein as carrier was far more effective than bsa and mouse serum albumin to make human c-peptide (hcp) immunogenicity in mice. twelve monoclonal antibodies (mcab) were obtained after fusion of ns-1 myeloma cells with spleen cells from two balb/c mice immunized with hcp-ascaris protein conjugate. eight mcab were characterized and all of them were of igg1 subclass. affinities of the mcab for hcp were in the range of 0.03-0.85 x 10(9) mol-1. although all 8 ... | 1989 | 2475269 |
| antiallergic effects of 4-[2-oxo-3-(1h-tetrazol-5-yl)-2h-chromen-8-yloxy]-bu tyric acid. | antiallergic effects of 4-[2-oxo-3-(1h-tetrazol-5-yl)-2h-chromen-8-yloxy]-buty ric acid (c4c) were studied. c4c is an active principal metabolite of an orally effective antiallergic agent, kp-136. c4c (0.2-1 mg/kg, i.v.) markedly inhibited the mast cell-mediated homologous pca of rats and the experimental allergic asthma of rats and guinea pigs, although it had almost no effects on heterologous pca and compound 48/80-induced cutaneous response in rats. c4c (0.2 mg/kg, i.v.) was scarcely effectiv ... | 1989 | 2475659 |
| inhibitory effects of beta-adrenergic stimulants on increased vascular permeability caused by passive cutaneous anaphylaxis, allergic mediators, and mediator releasers in rats. | the effects of isoproterenol, salbutamol, theophylline, and forskolin on ige antibody-mediated homologous passive cutaneous anaphylaxis (pca) and on skin reactions caused by allergic mediators and mediator releasers were investigated in rats. isoproterenol and salbutamol dose-dependently inhibited the pca and skin reactions caused by histamine, serotonin, and leukotriene c4 (ltc4), elicited at the same time in the same rat. these agents also dose-dependently inhibited the skin reactions caused b ... | 1989 | 2479953 |
| a patch-clamp study of effects of dihydroavermectin on ascaris muscle. | 1. effects of bath-application of the anti-parasitic agent 22,23-dihydroavermectin b1a (dhavm 20 fm to 0.2 microm) on outside-out and inside-out patches from collagenase-treated muscle membranes of ascaris suum were examined. 2. dhavm was tested as a gamma-aminobutyric acid (gaba) agonist by application to outside-out patches. dhavm failed to open characteristic gaba channels even when high concentrations (20 nm to 0.2 microm) were used. these high concentrations of dhavm also failed to potentia ... | 1989 | 2480169 |
| comparison of collagen gene sequences in ascaris suum and caenorhabditis elegans. | the nucleotide sequences of a 3060-bp fragment containing almost the entire coding sequence of one ascaris suum collagen gene, and a 3019-bp pair fragment containing the 3' end of another a. suum collagen gene have been determined. the polypeptides encoded by these genes show a striking similarity to two caenorhabditis elegans cuticular collagens, both in the position of the triple-helical regions and in the position of cysteine residues. the results of northern blot hybridisation experiments to ... | 1989 | 2482444 |
| [incidence of infection by intestinal parasites among school children in santiago, chile, 1988-1989]. | in december 1988-february 1989 period, a survey on enteroparasitic infections in children (mean age 8.7 years; males 54.4% and females 45.6%) from five schools located in santiago, chile, was undertaken. to each of these individuals, three samples were obtained in order to perform in them the following examinations: co-proparasitological study, modified ziehl-neelsen staining for detecting cryptosporidium sp. and cellulose adhesive test for enterobius vermicularis. parasitic elements were found ... | 1989 | 2484851 |
| [massive ascariasis of the bile ducts and posterior relapse]. | a 7 year old girl presented with persistent right upper abdominal colicky pain, fever, elevated white blood cells count, high blood sedimentation rate and mild liver enlargement. at surgical exploration 33 live ascarides (ascaris lumbricoides) were taken off from the hepatic duct. medical treatment with mebendazole was given in full doses after surgery. she remained well for six years except for intermittent episodes of colicky right upper abdominal pain. at age 13 year ascarides were again demo ... | 1989 | 2485505 |
| obstruction of the nasolacrimal duct by ascaris lumbricoides. | although ascaris lumbricoides infestation is extremely prevalent in some populations, the nematode is an extremely rare cause of nasolacrimal duct obstruction. obstruction of the nasolacrimal duct in a 4-year-old brazilian girl by a young adult a. lumbricoides is reported. in contrast to previously reported cases, the nematode involved the inferior, rather than superior, canaliculus and punctum. | 1989 | 2487208 |
| enteric parasites and hiv infection: occurrence in aids patients in rio de janeiro, brazil. | the occurrence of intestinal parasites, its relation with the transmission mechanism of hiv, and the clinical state of the aids patients, were analyzed in 99 group iv patients (cdc, 1986), treated at "hospital universitário pedro ernesto" (hupe), between 1986 and 1988. the group consisted of 79 (79.8%) patients whose hiv transmission mechanism took place through sexual contact and of 16 (20.2%) who were infected through blood. feces samples from each patient were examined by four distincts metho ... | 1989 | 2487448 |
| environmental contamination by toxocara sp eggs in public areas of salvador, bahia state, brazil. | a survey of parasite eggs and cysts in soil and dog feces collected in public places of 23 boroughs of salvador, a city in the northeast of brazil, was performed. high degree of contamination by toxocara sp eggs was observed in all boroughs studied; other parasites found included: ascaris lumbricoides, hookworms, whipworms and protozoan cysts. parks and public gardens were more contaminated than streets and beaches for all parasites, including toxocara sp. | 1989 | 2487776 |
| allergen-stimulated release of mediators into sheep bronchoalveolar lavage fluid. effect of cyclooxygenase inhibition. | products of arachidonic acid have been implicated as potential mediators of allergic airway responses in sheep and in humans. we therefore measured the release of arachidonate metabolites into sheep bronchoalveolar lavage fluid (balf) after local instillation of ascaris antigen, using a highly specific and sensitive approach, gas chromatography-negative ion-chemical ionization mass spectrometry. allergen instillation caused increases in the levels of the potent bronchoconstrictors prostaglandin ... | 1989 | 2492175 |
| helminth and snail survey in harerge region of ethiopia with special reference to schistosomiasis. | 2300 persons from 25 communities in harerge administrative region were examined for intestinal helminths. the overall prevalence rates were: schistosoma mansoni 19.4%, ascaris lumbricoides 13.4%, trichuris trichiura 7.9%, and taenia species 5.8%. other parasites found in less than 3% included: hymenolepis nana, hymenolepis diminuta, enterobius vermicularis, strongyloides stercoralis and hookworms. three age groups, 5-9, 10-14, and 15-19 years, had approximately similar prevalence (34.9-38.8%), b ... | 1989 | 2496975 |
| effects of the chitin synthesis inhibitor diflubenzuron on development of ascaris suum and haemonchus contortus. | the potential of the chitin synthesis inhibitor diflubenzuron (dfb) to alter the development of the parasitic nematodes (ascaris suum and haemonchus contortus was investigated. dfb given orally (10 mg kg-1 per day for 30 days) to sheep inoculated with h. contortus infective larvae did not prevent the establishment of adults or affect fecal egg output. however, there was a significant (greater than 90%) decrease in the number of infective larvae recovered from fecal cultures derived from lambs ha ... | 1989 | 2505433 |
| glycogen synthesis in the obliquely striated muscle of ascaris suum. | a glycogen synthase, designated gs ii, which occurs in a protein/carbohydrate complex has been purified from ascaris suum muscle. the purified gs-ii complex which is eluted from concanavalin-a--sepharose contains proteins with mr 140,000 and 66,000 and a glycoprotein with a carbohydrate/protein mass ratio of 3:1. gs ii activity was totally dependent on glucose 6-phosphate, but exogenous glycogen was not required for polysaccharide synthesis. the gs-ii complex was not phosphorylated by cyclic-amp ... | 1989 | 2506012 |
| effect of gas phase on carbohydrate metabolism in ascaris suum larvae. | the in vitro metabolism of [1-13c]glucose by ascaris suum third and fourth-stage larvae was analyzed under different gas phases using 13c nuclear magnetic resonance spectroscopy (13c-nmr). third-stage larvae (l3) incubated under a gas phase of 85% n2/5% o2/10% co2 produced trace amounts of [13c]succinate, and molted to fourth-stage larvae (l4) between days 3 and 4 in vitro. however, they appeared to arrest as l3s when incubated under air, or 85% n2/5% o2/10% co2 in the presence of 2 mm potassium ... | 1989 | 2509908 |
| intestinal helminths in akaki town, with special emphasis on the epidemiology of schistosoma mansoni. | two thousand, three hundred and nine stool specimens from about 5% of the residents of akaki were examined by kato thick smear technique for helminthic infections. the prevalence of various parasites was as follows: schistosoma mansoni, 1.5%; ascaris lumbricoides, 40.7%; trichuris trichiura, 27.5%, enterobius vermicularis, 2.2%; taenia saginata, 3.2%; and hymenolepis nana, 0.6%. infected biomphalaria pfeifferi snails were collected from the fanta stream, and 12% of the residents along the stream ... | 1989 | 2513182 |
| divalent hapten-induced intestinal anaphylaxis in the mouse: uptake and characterization of a bystander protein. | we examined the mucosal barrier function during anaphylaxis induced by the hapten n,n'-di-2,4,dinitrophenyl-lysine (di-dnp-lysine) in bdf1 female mice immunized with dinitrophenylated ascaris suum extract. immunized mice were gavaged with 10 mg or 50 mg of ovalbumin (ova) with or without n,n'-di-2,4,-dnp-lysine (di-dnp-lysine). animals that received di-dnp-lysine underwent anaphylaxis and were observed to have significantly greater serum concentrations of immunoreactive ova (iova) than control m ... | 1989 | 2514138 |
| [ascaris hepatic abscess]. | an 18 months old infant with hepatic abscesses was studied. ultrasonographic examination of the liver revealed 2 abscesses in the right lobe of the liver containing elongated hyperecogenic structures compatible with ascaris lumbricoides. antibiotic and antihelmintic treatment was followed by complete clinical recovery. | 1989 | 2518030 |
| cardiac arrest postoperatively in a patient infected with ascaris, the roundworm. | | 1989 | 2519513 |
| an abattoir survey of the prevalence of gastro-intestinal helminths and stephanurus dentatus in pigs in belize. | in an abattoir survey in belize 137 pigs were examined for gastro-intestinal helminths and stephanurus dentatus. hyostrongylus rubidus, physocephalus sexalatus, globocephalus species and trichostrongylus colubriformis were recorded for the first time. ascarops strongylina, ascaris suum, macracanthorynchus hirudinaceus, strongyloides ransomi, trichuris suis, oesophagostomum species and s. dentatus were also found. oesophagostomum species (45%) and s. dentatus (42%) were the most prevalent. the pr ... | 1989 | 2529683 |
| production and distribution of immunoglobulin-bearing cells in the intestine of young pigs infected with ascaris suum. | pigs of 10 days-1 month old were orally infected with eggs of ascaris suum at different rates and inoculation schedules. histological sections from various parts of the small intestines were prepared to observe the production and localization of immunoglobulin-bearing cells. fluorescent antibody and immunoperoxidase staining methods were used to determine the number of igm-, iga- and igg-producing plasma cells in the intestinal lamina propria. significant increases in immunoglobulin-bearing cell ... | 1989 | 2531490 |
| parasitic, bacterial and viral pathogens isolated from diarrhoeal and routine stool specimens of urban bangladeshi children. | few data exist in bangladesh on longitudinal, community-based studies of bacterial or parasitic pathogens identified in routine and diarrhoeal stools of urban dwelling children. we undertook the following study on 343 children of age less than 6 years who resided in one of 51 slum settings in dhaka, bangladesh, between october 1984 and february 1986. specimens from diarrhoeal episodes and from routine stools obtained at 3-monthly intervals were examined for parasites, rotavirus and pathogenic ba ... | 1989 | 2537431 |
| pharmacology of l-660,711 (mk-571): a novel potent and selective leukotriene d4 receptor antagonist. | l-660,711 (3-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl) ((3-dimethyl amino-3-oxo propyl)thio)methyl)thio)propanoic acid is a potent and selective competitive inhibitor of [3h]leukotriene d4 binding in guinea pig (ki value, 0.22 nm) and human (ki value, 2.1 nm) lung membranes but is essentially inactive versus [3h]leukotriene c4 binding (ic50 value in guinea pig lung, 23 microm). functionally it competitively antagonized contractions of guinea pig trachea and ileum induced by leukotriene (lt) d ... | 1989 | 2540892 |
| effects of combined receptor antagonists of leukotriene d4 (ltd4) and platelet-activating factor (paf) on rhesus airway responses to ltd4, paf and antigen. | rhesus monkeys with ige-mediated asthmatic-type responses to ascaris suum antigen were pretreated with a combination of 2 receptor antagonists to leukotriene d4 (ltd4) and platelet-activating factor (paf). this combination of anti-ltd4 and anti-paf was shown to inhibit airway responses to either ltd4 or paf in separate experiments in these ascaris airway-reactive animals. when the same combination of ltd4 and paf receptor antagonists was used to pretreat the same animal prior to aerosol challeng ... | 1989 | 2542169 |
| purification and properties of the cyclic 3',5'-amp-binding protein from the muscle of the nematode ascaris suum. | the cyclic 3',5'-amp-binding protein was isolated from the muscle of ascaris suum and purified to apparent homogeneity. it migrated as a protein with a relative mr 54,000 on electrophoresis under denaturing conditions. on gel filtration columns it was eluted at a volume corresponding to a protein of mr greater than 200,000 under conditions which kept the cyclic 3',5'-amp-binding property intact. the purified catalytic subunit of protein kinase from ascaris and the c subunit of cyclic 3',5'-amp-d ... | 1989 | 2543296 |
| platyhelminth mitochondrial dna: evidence for early evolutionary origin of a trna(seragn) that contains a dihydrouridine arm replacement loop, and of serine-specifying aga and agg codons. | the nucleotide sequence of a segment of the mitochondrial dna (mtdna) molecule of the liver fluke fasciola hepatica (phylum platyhelminthes, class trematoda) has been determined, within which have been identified the genes for trna(ala), trna(asp), respiratory chain nadh dehydrogenase subunit i (nd1), trna(asn), trna(pro), trna(ile), trna(lys), nd3, trna(seragn), trna(trp), and cytochrome c oxidase subunit i (coi). the 11 genes are arranged in the order given and are all transcribed from the sam ... | 1989 | 2545889 |
| effect of nedocromil sodium on antigen-induced airway responses in allergic sheep. | we studied the effects of nedocromil sodium and sodium cromoglycate on early and late bronchial responses, the airway inflammation associated with the late response to inhaled ascaris suum antigen in allergic sheep in vivo, and the antigen-induced contractile responses of sheep tracheal smooth muscle in vitro. in addition, we examined the effect of nedocromil sodium on the development of antigen-induced airway hyper-responsiveness in this model. pretreatment with either nedocromil sodium or sodi ... | 1989 | 2547569 |
| l-663,536 (mk-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 - dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor. | l-663,536 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2, 2-dimethylpropanoic acid) is a potent inhibitor of leukotriene (lt) biosynthesis in intact human polymorphonuclear leukocytes (pmn) (ic50, 2.5 nm). similarly, l-663,536 inhibited a23187-induced ltb4 formation by rat peripheral blood and elicited pmn. at concentrations where inhibition of leukotriene biosynthesis occurred in human whole blood (1.1 microm), no effect was seen on cyclooxygenase or 12-lipoxygenase, an effect a ... | 1989 | 2548691 |
| purification and properties of cyclic-3',5'-gmp-dependent protein kinase from the nematode ascaris suum. | a cyclic-3',5'-gmp-dependent protein kinase was purified 7400-fold from the reproductive tract of female ascarids to a specific activity of 718 nmol min-1 mg-1 (histone as substrate). the yield of the preparation was 25%. the enzyme protein obtained was homogeneous as judged by isoelectrofocusing and polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate. the native enzyme behaved as a dimer of two 82-kda subunits in gel permeation chromatography on superose 12. the protein ... | 1989 | 2549874 |
| cytologic detection of parasites in cervical smears. | | 1989 | 2555991 |
| gaba receptors on the somatic muscle cells of the parasitic nematode, ascaris suum: stereoselectivity indicates similarity to a gabaa-type agonist recognition site. | 1. the gamma-aminobutyric acid (gaba) receptors on the somatic muscle cells of ascaris, which mediate muscle cell hyperpolarization and relaxation, have been characterized by use of intracellular recording techniques. 2. these receptors are like mammalian gabaa-receptors in that the response is mediated by an increase conductance to chloride ions. the gabaa-mimetic, muscimol, has a relative potency of 0.40 +/- 0.02 (n = 3) compared to gaba. 3. the stereoselectivity of the gaba receptor on ascari ... | 1989 | 2556203 |
| role of arachidonic acid metabolites in allergen-induced late responses. | the sheep model of allergic airway disease shares many pathophysiological similarities with allergic airway disease in humans. studies performed in this animal model present strong evidence that the release of arachidonic acid metabolites plays an important role in the development of late bronchial responses to antigen challenge. the release of leukotrienes through the lipoxygenase pathway during the acute bronchial obstruction after inhalation of ascaris suum antigen represents the key factor f ... | 1989 | 2557658 |
| intestinal parasitic infestation in rural communities: a focus for primary health care in nigeria. | a study carried out in four villages in two local government areas of oyo state in the southwestern part of nigeria, revealed that intestinal helminthiasis is still very prevalent in nigeria. ascaris is the most common helminth encountered and multiple infestation is also quite common. schoolchildren and pre-school children are the greatest sufferers of ascaris, while students and farmers are the greatest target for hookworm. the usefulness of a community-based distribution programme of health s ... | 1989 | 2558560 |
| entamoeba histolytica and other parasitic infections in south kanara district, karnataka. | single stool specimens collected from 1,020 apparently healthy people of the south kanara district, were processed for intestinal parasites using three parasitological methods viz. (a) direct smear in physiological saline and d'antoni's iodine, (b) zinc sulfate concentration method and (c) by culture in modified boek and drbolhav medium. of these 781 (76.51 per cent) were found to be infected with parasites. the prevalence of various intestinal parasites was: ascaris lumbricoides (48.33 per cent ... | 1989 | 2559118 |
| possible mode of action of toltrazuril: studies on two eimeria species and mammalian and ascaris suum enzymes. | the anticoccidial properties of toltrazuril in eimeria falciformis-infected mice were potentiated by the simultaneous application of pyrimethamine, trimethoprim, or sulfadimidine. the same drugs potentiate the effect of toltrazuril by killing e. tenella schizonts in chicken kidney-cell cultures. activities of some enzymes of the respiratory chain, such as succinate-cytochrome c reductase and nadh oxidase and succinate oxidase from mouse liver, were reduced in the presence of toltrazuril. the sam ... | 1989 | 2560189 |
| signaling properties of ascaris motorneurons: graded active responses, graded synaptic transmission, and tonic transmitter release. | the commissural motorneurons of the nematode ascaris are capable of transmitting signals passively over long distances with little decrement. this ability is due to the high resistivities of their membranes (davis and stretton, 1989). although these cells rely on their passive properties for long-distance signaling, voltage-sensitive channels are present in commissural membranes. these channels underlie the graded active responses that can be elicited at the offset of abrupt hyperpolarizing and ... | 1989 | 2563763 |
| ascariasis. | | 1989 | 2565520 |
| major sperm protein and actin genes in free-living and parasitic nematodes. | the dna from a number of free-living and parasitic nematode species was examined to determine the genomic number and distribution of dna sequences encoding two evolutionarily conserved proteins; the major sperm protein (msp) and nematode actin. ascaris and caenorhabditis msp cdna sequences and ascaris genomic actin sequences were used to probe southern blots of eco ri and hin d iii digested nematode dna. the number of msp genes varied widely between the 1 msp gene in ascaris and the 60 msp genes ... | 1989 | 2570394 |
| [the role of atopic background in the genesis of allergic manifestations in intestinal parasitoses]. | the previous literature and personal observations showed the predominant role of the atopic background in the appearance of the allergic manifestation in the parasitic infestation and especially in giardiasis. the lot investigated was made of 52 patients with allergic manifestations, also infested with giardia intestinalis or with ascaris lumbricoides. the hereditary collateral and personal allergic antecedents and the clearly deficient histaminopexy (1/20) were present in 1/2 of the patients. s ... | 1989 | 2573132 |
| [changes in the serum levels of lactate dehydrogenase, gamma- glutamyltransferase, glucose and alpha amino nitrogen in guinea pigs with experimental ascariasis]. | the studies were carried out on 90 male guinea pigs of which 75 were infected per os with a dose of ca. 5000 invasive eggs of ascaris lumbricoides suis. at the 1st, 2nd, 4th, 7th and 20th day of infection blood was taken from experimental and control animals. the activity of ldh and its liver fraction (spectrophotometric method), ggtp (circle test method) was determined. the level of glucose (orthotoluidin method) and alpha amino nitrogen (ninhydrin method was determined. in the course of larval ... | 1989 | 2573199 |
| antiallergic activity of picumast dihydrochloride in several animal species. | picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarin dihydrochloride) was compared with cromoglycate, ketotifen and mepyramine as an inhibitor of allergic and anaphylactoid reactions. 1. in guinea-pigs, pretreatment with picumast dihydrochloride given intravenously, orally or by inhalation prevented bronchospasm induced by antigen or histamine. the fraction of the bronchospasm remaining after mepyramine pretreatment was further reduced by picumast dihydroch ... | 1989 | 2576354 |
| effect of picumast dihydrochloride on antigen-induced early and late airway responses in allergic sheep. | in this study the effects of picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorobenzyl)piperazine-1-yl]propoxycoumarine++ + dihydrochloride) a novel antiallergic agent, on antigen-induced early and late responses in allergic sheep were examined. for all studies picumast dihydrochloride was administered as an aerosol approximately 20 min before airway challenge with ascaris suum antigen. allergic sheep were challenged on four occasions each greater than or equal to 14 days apart: one placebo tr ... | 1989 | 2576357 |
| serodiagnosis of ocular toxocariasis: a comparison of two antigens. | this study was designed to compare the sensitivity and specificity of enzyme linked immunosorbent assay (elisa) for the serodiagnosis of ocular toxocariasis using toxocara canis embryonated egg antigen (tee) and toxocara excretory-secretory or exoantigen (tex) produced in vitro. tee and tex elisa were comparably sensitive, but tex elisa was better able to discriminate between serum samples from patients with ocular toxocariasis and those from patients with retinoblastoma. in addition, preabsorpt ... | 1985 | 2578482 |
| smooth muscle contraction and release of histamine and slow-reacting substance of anaphylaxis in pulmonary tissues isolated from guinea pigs passively sensitized with igg1 or ige antibodies. | in previous studies, we have provided evidence that different fc receptors mediate antigen-induced pulmonary smooth muscle contractile responses after passive sensitization of guinea pigs with igg1 or ige antibodies. in this study, we examined the relationship between contraction and release of histamine and slow-reacting substance of anaphylaxis (leukotrienes) in superfused trachea and parenchymal strips as well as mediator release from minced lung fragments after passive sensitization of guine ... | 1985 | 2578761 |
| antigen-specific anti-phosphocholine antibodies: binding site studies. | the present investigation extends our initial evaluation of the evolution of antigen selection mechanisms for antibodies of a "single" specificity. the binding sites of 11 mouse anti-pc antibodies produced in response to the bacterium p. morganii or the nematode a. suum were characterized for both hapten and hapten plus carrier specificity. all of the anti-p. morganii hp belonged to the m603 anti-pc antibody family, whereas all the a. suum hp belonged to the m511 family. of the eight anti-p. mor ... | 1985 | 2579145 |
| gamma-aminobutyric acid- and piperazine-activated single-channel currents from ascaris suum body muscle. | gamma-aminobutyric acid (gaba)- and piperazine-activated single-channel currents were recorded from the bag region of the somatic muscle of the nematode parasite ascaris suum. cell-attached and outside-out patch-clamp techniques were used. clean membranes were routinely prepared using collagenase. gaba (concentrations greater than 1 microm) or piperazine (concentrations greater than 200 microm) applied to the extracellular surface of the patches brought about the opening of channels producing re ... | 1985 | 2579701 |
| helminth ova in soil from children's playgrounds in calabar, nigeria. | a study was undertaken to examine the helminth ova in soil from children's playgrounds in calabar, nigeria. a total of 150 soil samples were collected from the playgrounds studied. ova of ascaris lumbricoides (10 percent, 12 percent and 20 percent) were found in these playgrounds. in addition, each of the following helminth ova was found respectively in each of the playgrounds: trichuris vulpis (4 percent), toxocara canis (8 percent) and strongyloides stercoralis (6 percent). the public health a ... | 1989 | 2582487 |
| cytoplasmic intermediate filament proteins of invertebrates are closer to nuclear lamins than are vertebrate intermediate filament proteins; sequence characterization of two muscle proteins of a nematode. | the giant body muscle cells of the nematode ascaris lumbricoides show a complex three dimensional array of intermediate filaments (ifs). they contain two proteins, a (71 kd) and b (63 kd), which we now show are able to form homopolymeric filaments in vitro. the complete amino acid sequence of b and 80% of a have been determined. a and b are two homologous proteins with a 55% sequence identity over the rod and tail domains. sequence comparisons with the only other invertebrate if protein currentl ... | 1989 | 2583097 |
| exposure to 1 ppm ozone attenuates the immediate antigenic response of canine peripheral airways. | the effect of oxidant exposure on the immediate airway response to immunologic challenge is controversial. we investigated the response of canine peripheral airways to antigen aerosol, 1-3 h and 24 h after a 5-min exposure to 1 ppm ozone. in dogs that were natively sensitive to ascaris suum antigen, resistance to flow through the collateral system (rcs) was measured using the wedged bronchoscope technique. in eight dogs, four sublobar segments of each lung were wedged: two were exposed to ozone ... | 1989 | 2585539 |
| preexposure to ozone blocks the antigen-induced late asthmatic response of the canine peripheral airways. | the influence of exposure of the airways to ozone on acute allergic responsiveness has been investigated in several species. little is known, however, about the effect of this environmental pollutant on the late asthmatic response (lar) in animals in which it is exhibited. the purpose of this study was to evaluate this effect in the canine peripheral airways and to assess the potential role of mast cells in modulating the effect. a series of experiments on seven mongrel dogs demonstrated that th ... | 1989 | 2585540 |
| the effect on fetal growth of protozoan and helminthic infection during pregnancy. | this is a prospective study of 14,914 pregnant women conducted in guatemala city, guatemala. stool samples were obtained from the studied patients before the first prenatal visit (mean gestational age 21.6 +/- 8.4 weeks) for the diagnosis of parasitic infections during pregnancy. forty-four percent had at least one parasite detected, and 24% were infected with helminths. ascaris lumbricoides was the most prevalent (14.5%). infected mothers were less educated, had less adequate water and sanitary ... | 1989 | 2586958 |
| a study of the efficacy and safety of albendazole (zentel) in the treatment of intestinal helmenthiasis in kenyan children less than 2 years of age. | one hundred children comprising of 57 males and 43 females aged between 8 and 24 months entered the study. 46 children had single and 54 children had multiple helminth infections. all children received albendazole 200 mg (10 ml) suspension as a single dose. albendazole proved very effective and safe in the treatment of single and multiple helminth infections in children under 2 years of age, achieving cure rates of 100% in both ascaris lumbricoides and necator americanus respectively, 83% in tri ... | 1989 | 2591328 |
| [strategy of ascaris lumbricoides and trichuris trichiura for the environmental contamination, in an endemic area]. | the distribution of frequencies of the number per grame of ascaris lumbricoides and trichuris trichiura in the faeces of naturally infected human in endemic areas, were found following a negative binomial distribution and an overdispersal pattern, independently of the ages of hosts. these results show, that only few hosts, independently of their ages, are involved in the higher environment contamination. | 1988 | 2593824 |
| the epidemiology of ascaris lumbricoides and other soil-transmitted helminths in primary school children from ile-ife, nigeria. | an epidemiological survey of intestinal helminthiases was conducted on 766 primary school children aged 5-16 years from ile-ife, nigeria. on the basis of stool examinations, the prevalence of ascaris lumbricoides, trichuris trichiura, hookworm and strongyloides stercoralis was 88.5, 84.5, 33.1 and 3% respectively. intensity of infection was measured indirectly by egg counts for each species of helminth and also by counting worms passed after chemotherapy in the case of a. lumbricoides. the influ ... | 1989 | 2594419 |
| soil-transmitted helminth infections in school children from cocle province, republic of panama. | a survey was carried out to determine values for the prevalence and intensity of infection of intestinal helminths in children living in cocle province, republic of panama. the data set consisted of the results of microscopic examinations (modified kato katz technique) of stool samples collected in november 1987 from 661 children attending primary schools in 4 communities in the province. the overall prevalences of ascaris lumbricoides, hookworm and trichuris trichiura infections were found to b ... | 1989 | 2594420 |
| the weight/length profiles of ascaris lumbricoides within a human community before mass treatment and following reinfection. | weight and length profiles are presented of 3505 ascaris worms recovered after mass anthelmintic treatment of a human community in january 1984 and, after an 11 month period of reinfection, in november 1984. male and female worms recovered after reinfection were significantly heavier and longer than those expelled after initial treatment (p less than 0.0001). multiple regression models were employed to examine variability in parasite size. a positive influence of host body weight on the weight o ... | 1989 | 2594421 |
| a multi-allergen screening test for suspected allergic disease in coloured children. | the measurement of total serum ige levels is widely used as a screening test for allergic disease but lacks specificity in south african subjects because of the presence of ethnic and environmental factors, e.g. parasite infestation, which also raise total serum ige. the reliability of a new in vitro multi-allergen test, phadiatop (pharmacia), which is not influenced by parasitic infestation, was investigated as a screen for allergic disease in coloured children. phadiatop assays and total serum ... | 1989 | 2595485 |
| prevalence and seasonal fluctuations of intestinal parasitic infections in the nablus area, west bank of jordan. | a total of 22,970 stool specimens collected from patients attending the central medical laboratory in the city of nablus in the period of 1981-1986 were examined for intestinal parasites. of these 7412 (32.3%) were positive. entamoeba histolytica (22.9%), giardia lamblia (7.3%), and ascaris lumbricoides (5.7%) were the most prevalent intestinal parasites found. other intestinal parasites present included hymenolepis nana, trichomonas hominis, trichuris trichiura, taenia saginata, enterobius verm ... | 1989 | 2596904 |
| prevalence of toxocara ova in some schools and public grounds in northern and central jordan. | two hundred and twenty-six soil samples were collected from school playgrounds and public places in four cities and 17 villages in northern and central jordan. toxacara eggs were found in 35 (15.45%) of the samples. viable eggs were found in 18 samples, with viability ranging from 20 to 78%, and among these 18 samples the mean number of viable eggs per 5 g soil was 5.5 +/- 4.58 s.d. (range one to 15 eggs). nine of 94 samples collected from public places and five of 86 samples collected from scho ... | 1989 | 2596905 |
| inhibitory effects of tetragalloylglucose on the complex ii of mitochondrial respiratory chain of ascaris muscle. | the effects of tetragalloylglucose (1,2,3,6-tetra-o-galloyl-beta-d-glucose) on purified complex ii (succinate-ubiquinone oxidoreductase) of the mitochondrial electron transport system of ascaris muscle were studied. both succinate-ubiquinone-1 (q1) oxidoreductase, and succinate dehydrogenase measured with 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (mtt) in the presence of phenazine methosulfate (pms) were inhibited by tetragalloylglucose. the inhibitions of both reductase acti ... | 1989 | 2605704 |
| mixed infections in childhood diarrhoea: results of a community study in kiambu district, kenya. | one thousand four hundred and twenty diarrhoea specimens from 846 children aged 0 to 60 months were collected and analysed for bacteria, parasites and rotavirus over a 16 month period, from june 1985 to september 1986 inclusive. the study was conducted in 4 villages situated in kiambu district, kenya. all the specimens were analysed for rotavirus and parasites, including cryptosporidium. the majority of the specimens were analysed for enteropathogenic escherichia coli (epec), shigella, salmonell ... | 1989 | 2606013 |
| slow active potentials in ventral inhibitory motor neurons of the nematode ascaris. | the ability of ventral inhibitory motor neurons of the nematode ascaris to generate slow depolarizing potentials was investigated using intracellular recording and current injection. in quiescent cells, regenerative depolarizations with peak amplitudes of approximately 20 mv and durations of several 100 ms were evoked in response to brief depolarizing current pulses. repetitive slow potentials were produced in response to sustained depolarizing currents in a threshold-dependent manner. repetitiv ... | 1989 | 2607486 |
| [changes in the indices of the b-immunity system in patients with intestinal nematodiases after treatment]. | a decrease in the titers of antibodies to opportunistic bacteria has been observed in 100 patients suffering from ascariasis, trichocephaliasis and mixed invasion (ascariasis and trichocephaliasis). the immune suppression was higher in patients with mixed invasion. medamine treatment enhances the suppression of antibody production. changes in humoral immunity parameters are due to the effect of helminthic antigens and the composition of escherichia in the large intestine of the affected subjects ... | 1989 | 2615705 |
| [the biological activity of the lipopolysaccharide complexes in ascarids]. | lipopolysaccharide complex with chemical structure similar to that of complexes of microbial origin was isolated from ascaris suum by not phenol-aqueous extraction. | 1989 | 2615713 |
| the antibody recognition profiles of humans naturally infected with ascaris lumbricoides. | a semi-quantitative analysis of individual human antibody responses to larval ascaris excretory and secretory (es) antigens using radioimmunoprecipitation and sds-page is presented. a significant relationship was observed between the intensity of antibody-precipitated radiolabelled es antigens and host age. the antibody response profile followed a similar age-related pattern to that of intensity of infection, with blood samples from 5-9-year-old children showing the strongest banding patterns an ... | 1989 | 2616191 |
| the impact of improvement of water supply and sanitation facilities on diarrhea and intestinal parasites: a brazilian experience with children in two low-income urban communities. | during the second half of 1986 the impact of the improvement of water supply and excreta disposal facilities on diarrheal diseases and intestinal parasitosis was studied in 254 children up to six years of age from two favelas (shanty towns) of belo horizonte, brazil. the estimated incidence of diarrhea was 6.2 episodes/child year and the estimated period prevalence reached 31.0 episode days/child/year. the point prevalence of parasitosis was 70.7% (ascaris lumbricoides: 55.4%, trichuris trichiur ... | 1989 | 2617116 |
| geohelminth infection of children from rural plantations and urban slums in malaysia. | this study compares levels of geohelminth infection in children living in rural estates and urban slum areas of malaysia. the statistical characteristics of geohelminth infection in 1499 children from birth up to 15 years of age, living in rural estates, were analysed according to age, sex and ethnic origin and compared with the same statistics for 1574 slum-dwelling children of similar age groups and ethnic origins. the prevalence and intensity of ascariasis and trichuriasis were significantly ... | 1989 | 2617652 |
| ym461, a paf antagonist, blocks antigen-induced late airway responses and airway hyperresponsiveness in allergic sheep. | we examined the effect of an orally active antagonist, ym461, of platelet activating factor (paf) on antigen-induced early and late airway responses and on the development of airway hyperresponsiveness 24 h after challenge in allergic sheep. early and late airway responses were determined by measuring specific lung resistance (srl) before and periodically after challenge. airway responsiveness was determined from the slopes of dose-response curves of srl vs. increasing doses of carbachol aerosol ... | 1989 | 2620695 |
| [the autodehelminthizing capacity of the soil]. | a description of the methodology used for the study of soil deshelminthizing processes is presented, as well as some of the results already obtained. this method has already been tested on the soil of different countries, including mexico, and it is still in an experimental stage; notwithstanding, the results obtained are encouraging. further research is needed for its successful application as a tool on the control of human soilborne diseases. | 1989 | 2626721 |
| af1, a sequenced bioactive neuropeptide isolated from the nematode ascaris suum. | an fmrfamide-like neuropeptide, named af1, was isolated from head extracts of the nematode ascaris suum using five steps of hplc. af1 is a heptapeptide with the amino acid sequence lys-asn-glu-phe-ile-arg-phe-nh2. synthetic af1 (10(-9) to 10(-7) m) rapidly and reversibly abolished slow membrane potential oscillations of identified ventral and dorsal inhibitory motoneurons and selectively reduced their input resistances. synaptic transmission was not blocked. in intact ascaris, af1 inhibited loco ... | 1989 | 2627377 |
| albendazole in the treatment of goehelminth infections in children. | children with mixed helminthic infections between the ages of 2 and 14 years, from a slum area, were treated with two regimes of albendazole. a majority of children had moderate to heavy infections with trichuris trichiura (greater than 70%) and ascaris lumbricoides (greater than 84%). children treated with a single 400 mg dose of albendazole showed a very good response in ascariasis with 100% cure rate irrespective of the severity of infection. in trichuriasis (n = 40), a cure rate of 50% was o ... | 1989 | 2627728 |
| description of a new species of thynnascaris dollfus, 1933 (nematoda: anisakidae) from the stomach of the marine teleost fish rachycentron canadus (linnaeus). | a new species of the nematode genus thynnascaris obtained from the teleost rachycentron canadus (linnaeus) is reported. a detailed examination of this specimen has allowed us to erect a new species thynnascaris to accommodate the worm. it shows remarkable differences from other known species of thynnascaris in respect of body size, length of the oesophageal appendix and intestinal caecum, location of nerve ring and excretory pore, on the papillae on the lips arrangement, type of the striations o ... | 1989 | 2629768 |
| [hypochromic anemia associated with ascariasis and giardiasis in children]. | the purpose of the study was determination of the frequency of the association of hypochromic anaemia with infections by ascaris lumbricoides and giardia intestinalis. among 5603 studied patients of either sex, aged 3 to 18 years ascaridiasis alone was diagnosed in 226 children (4%), and giardiasis alone in 106 cases (1.9%). the frequency of this anaemia in these groups ranged from 6% to 16%. | 1989 | 2633492 |
| [alpha-amylase activity in serum and some organs of guinea pigs with larval ascariasis]. | the studies were carried out on 40 guinea pig males weighting about 230 g. the experimental animals were infected with 7000 invasive eggs of ascaris suum. on the 3-rd, 7-th and 10-th day after infection the activity of alpha-amylase was estimated according to caraway's method in serum, liver, pancreas, lungs, kidneys and spleen. the infection of guinea pigs results in increased activity of enzyme in serum and spleen, and decreased in pancreas, liver, kidneys and lungs. on the 3-rd day after infe ... | 1989 | 2633502 |
| [trypsin and alpha-amylase activity in the pancreas of guinea pigs. i. the influence of infective dose and duration of infection by ascaris suum goeze, 1782]. | the studies were carried out on guinea pig males weighting about 280 g. the animals were infected with 5000 or 20,000 invasive eggs of ascaris suum. on the 3-rd, 7-th, 10-th and 14-th day of invasion the animals were dissected. lungs were weighted, and the number of ascaris larvae was estimated using baermann method. the activity of alpha-amylase (fennel's method) and trypsin (anson's method) were examined in pancreas homogenate. the infection of guinea pigs with a. suum larvae resulted in a dec ... | 1989 | 2633503 |
| the pyruvate dehydrogenase complex from anaerobic mitochondria of the parasitic nematode ascaris suum: stoichiometry of phosphorylation and inactivation. | | 1989 | 2634345 |
| [inhalation of a precursor analogue of vasoactive intestinal polypeptide (leu17 vip-gly-lys) protects ascaris-induced bronchoconstriction in dog]. | we studied in vivo the effects of pre-inhalations of vasoactive intestinal polypeptide (vip) and a precursor analogue of vip (leu17 vip-gly-lys: previp) in mongrel dogs bronchoconstricted by ascaris. an inhalation of previp solution (2 mg/5 ml saline) gave significant protection for 120 min against increases in respiratory resistance (rrs) and decreases in dynamic compliance (cdyn) induced by ascaris challenges. an inhalation of vip solution (2 mg/ml saline) also gave significant protection for ... | 1989 | 2634376 |
| sonographic diagnosis and follow-up in a patient with pancreatic roundworms. a case report. | ultrasonography showed roundworms (ascaris lumbricoides) in the main pancreatic duct of a child with acute pancreatitis. this method was used to follow-up gradual reversion to normal during medical treatment. | 1989 | 2645664 |
| effect of screening and treatment on imported intestinal parasite infections: results from a randomized, controlled trial. | a randomized, controlled trial was undertaken to evaluate the effects of a screening program for intestinal parasite infection in newly arrived southeast asian refugees to montréal, québec, canada, during 1982-1983. families assigned to the screened groups were examined, infected persons were treated and followed until they were infection-free, and all screened families were reexamined at six months. families assigned to the control groups were examined at six months only. statistically signific ... | 1989 | 2646918 |
| carboxypeptidase inhibitors from ascaris suum: the primary structure. | the carboxypeptidase a inhibitor from ascaris suum was isolated from aqueous extracts by affinity chromatography toward immobilized carboxypeptidase a. the amino acid sequence is dqvrkclsdt10dctngekcvq20knkicstive30iqrcekehft40ipcksnndcq50vwahekicn k60lpwgl65 . the carboxypeptidase a inhibitor is not homologous with the chymotrypsin/elastase or trypsin inhibitors from ascaris, but shows homology in a 9-residue internal sequence with the 37/39-residue carboxypeptidase inhibitors from tomato and p ... | 1989 | 2648995 |
| prevalence of biliary tract disease in india: a sonographic study in adult population in kashmir. | sonography was used to investigate the prevalence of symptomatic and silent biliary tract disease, in free living urban population in kashmir. a randomly drawn sample of 1695 subjects aged 15 years or above was interviewed by a questionnaire. twenty six had previous cholecystectomies, all for gall stones. ultrasonography was carried out on 1104 (65.1%). the responder rates for ultrasonography in men (64.3%) and in women (66.0%) were similar (p greater than 0.2). gall stones were detected in 49 a ... | 1989 | 2649414 |
| synergistic effect of migrating ascaris larvae and escherichia coli in piglets. | the effect of intestinal flora on the establishment, development and pathogenicity of ascaris suum larvae in piglets (large white breed) was investigated. the infected piglets with ascaris and escherichia coli showed signs of pneumonia, cough with respiratory difficulties initially even though these moderated with time. they lost appetite and showed signs of unthriftiness with loss of weight. the packed cell volume was normal but the differential leucocyte counts of the pigs infected with ascari ... | 1989 | 2656846 |
| prehistoric parasitism in tennessee: evidence from the analysis of desiccated fecal material collected from big bone cave, van buren county, tennessee. | eight samples of desiccated human feces collected from big bone cave (40vb103), van buren county, tennessee, were analyzed to determine the presence of ecto- and endoparasitic infection among the prehistoric population using the cave. radiocarbon-dated torch material from the cave indicated that it was a locus of human activity 2,177 +/- 145 yr ago. parasitic species identified were: ascaris lumbricoides, enterobius vermicularis, fleas of the tribe phalacropsyllini, and protozoan cysts. the cyst ... | 1989 | 2656962 |
| physicochemical characterization and monoclonal and polyclonal antibody recognition of baylisascaris procyonis larval excretory-secretory antigens. | baylisascaris procyonis larval excretory-secretory (es) antigens consisted of complex glycoproteins ranging from 10 kda to over 200 kda as determined by sodium dodecyl sulfate polyacrylamide gel electrophoresis and lectin binding. five monoclonal antibodies (bapr1-bapr5) produced against b. procyonis es antigens were assayed by western blotting with larval es antigens from b. procyonis, baylisascaris melis, baylisascaris transfuga, ascaris suum, and toxocara canis. bapr1 and bapr2 recognized per ... | 1989 | 2668490 |
| antigen-coated sepharose beads induce airway eosinophilia and airway hyperresponsiveness in cynomolgus monkeys. | a method of inducing sustained airway eosinophilia and airway hyperresponsiveness in primates has been developed. our method utilizes a series of intratracheal instillations of ascaris suum-coated sepharose 4b beads (3 x 10(5] administered once a week for four weeks. five cynomolgus monkeys (macaca fascicularis) demonstrating a naturally occurring skin and respiratory sensitivity to ascaris suum extract were studied. airway cell composition was measured by bronchoalveolar lavage (bal), and airwa ... | 1989 | 2675702 |
| trans-splicing in nematodes. | | 1989 | 2680571 |