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[bladder bilharzioma and carcinoma in a bilharzial bladder].over 7 years, 592 patients infected by schistosoma haematobium were detected. among these, 102 had a cystoscopy which found carcinoma in 3 patients, polypi in 1 and vesical "bilharzioma" (so-called pseudo-polyps) in 14. from the results of the biopsies and data from the medical literature the relationship between schistosomiasis and carcinoma in the schistosomial bladder is discussed, as well as the meaning of various lesions, such as malpighian metaplasia, papillomatous hyperplasia and glandula ...19836314531
differentiation of schistosomes by species, strain, and sex by using cloned dna markers.we have detected species, strain, and sex-specific genetic markers for the genus schistosoma by southern blot analysis of its dna using cloned dna segments of the schistosoma mansoni ribosomal gene as probes. restriction analysis of dna from eight different strains of s. mansoni, from africa and the caribbean, revealed that the predominant or major dna fragment containing the ribosomal gene unit was the same in each but that low copy number or minor fragments containing the gene varied. it was s ...19846322176
three serum markers of collagen biosynthesis in nigerians with cirrhosis and various infectious diseases.serum immunoreactive prolyl hydroxylase protein, galactosylhydroxylysyl glucosyltransferase activity, and the aminoterminal propeptide of type iii procollagen (s-pro(iii)-n-p) were measured in twenty patients with cirrhosis and ninety with various infectious diseases, and the values were compared with those in sixty apparently healthy nigerians. the means for all three markers were elevated significantly in the patients with cirrhosis (p less than 0.001), acute viral hepatitis (p less than 0.001 ...19846329766
observations on morbidity from schistosomiasis through a control program in middle egypt (1977-1981). 19846334705
analysis of human urine for mutagens associated with carcinoma of the bilharzial bladder by the ames salmonella plate assay.the ames salmonella plate assay was employed to test urine samples from bladder cancer patients and controls living in egypt for the presence of chemical mutagens. urine from five groups of egyptian adults were tested, including individuals with (1) neither bilharziasis nor bladder cancer, (2) urinary bilharziasis and normal urinary cytology, (3) urinary bilharziasis and atypical urinary cytology, (4) carcinoma of the bilharzial bladder, and (5) bladder cancer without bilharziasis. plates treate ...19836336979
the importance of animals in human schistosomiasis in south africa.the importance of animals in human schistosomiasis in south africa is reviewed. the prevalence of animal schistosome species in humans, the role of animals as reservoir hosts of schistosoma haematobium and s. mansoni, and the possibility of false-positive serological reactions in humans following exposure to animal or bird bilharzia are considered. it is concluded that, as regards animal schistosomes, at present only s. mattheei and a hybrid of s. mattheei and s. haematobium pose a potential thr ...19836337411
the canopic worm: role of bilharziasis in the aetiology of human bladder cancer. 19836338226
effectiveness of praziquantel against the south african strains of schistosoma haematobium and s. mansoni.a total of 137 black children from two schools in natal, infected with either schistosoma haematobium or s. mansoni, or both, were treated with praziquantel (biltricide; bayer-miles) at a dosage of 40 mg/kg body weight. dramatic reductions in egg output occurred within a matter of days and high cure rates (greater than or equal to 97%) were obtained in both s. haematobium and s. mansoni infections. side-effects were of short duration and not serious.19836344270
evaluation of enzyme linked immunosorbent assay (elisa) as a diagnostic tool for schistosomiasis.the sensitivity and specificity of the elisa were assessed in the diagnosis of schistosomiasis in two groups of school children, one attending a rural school where schistosomiasis is highly prevalent, the other attending a school in an urban locality where schistosomiasis is absent. the results showed that the elisa had a sensitivity of 92.2% and 100% in schistosoma mansoni and mixed infection, respectively. the specificity of the test increased from 92.1% to 98% when a fourth stool examination ...19836344354
the malumfashi project--an epidemiological, clinical and laboratory study. 19836344359
[schistosomal cor pulmonale]. 19836351191
proteolytic activity of schistosoma haematobium eggs from human urines in egypt. 19836355431
the curious case of the lateral-spined egg: schistosoma mansoni. 19836364471
long-term efficacy of single-dose oral treatment in schistosomiasis haematobium.a two-year follow-up was conducted in children who had been the subjects of a six-month double-blind trial in the single-dose treatment of schistosoma haematobium infection. the trial had assessed therapeutic efficacy of three oral preparations-praziquantel 40 mg/kg, metrifonate 10 mg/kg, and the 'combination' (concurrent niridazole 25 mg/kg and metrifonate 10 mg/kg administration). reduction in urinary egg excretion remained high up to follow-up at two years, based on a comparison of pre- and p ...19846369651
specific ige antibodies and ige containing circulating immune complexes in human schistosomiasis.ige antibodies (ige-ab) have been investigated in patients infected with s. mansoni, s. haematobium, s. mansoni and s. haematobium or s. intercalatum using an enzyme immuno assay based on the rast principle. antigens applied were crude extracts from s. mansoni, s. haematobium and s. japonicum adult worms. ige containing immune complexe (ige-cic) were determined by precipitation with peg and subsequent identification with i125 labelled antihuman ige. in the patients with schistosomiasis ige-ab to ...19836370478
lung-stage expression of a major schistosome surface antigen.the topographical expression of a glycoprotein of 180,000 molecular weight on the surface of lung-stage schistosoma mansoni schistosomula was determined by immunofluorescence microscopy using a monoclonal antibody. postfixation treatment with graded ethanols enhanced specific immunofluorescent staining of adult worms, and was required for detection of the antigen on the surfaces of lung-stage schistosomula. the epitope recognized by the monoclonal antibody was also present on the surfaces of adu ...19836371211
caribbean schistosomiasis. 19846390303
immunofluorescent analysis of renal biopsies in uncomplicated schistosoma haematobium infections in children.renal biopsies were studied by light and immunofluorescent microscopy in 13 young individuals with uncomplicated schistosoma haematobium infections. slight mesangial cell proliferation and matrix increase were found in three biopsies and focal interstitial inflammatory infiltrates were noted in six. however extensive igg (nine cases) and igm (seven cases) granular deposits were found in the mesangial areas. c3 was found in only three of these cases. clq, fibrinogen, iga and ige were not found de ...19846392575
[schistosomiasis and cancer of the bladder]. 19846399935
single dose oral treatment in urinary schistosomiasis: a double blind trial.a double blind trial of three oral preparations given in single doses for the treatment of schistosoma haematobium infection was carried out in schoolchildren; selection was biased towards those who excreted large quantities of eggs. praziquantel 40 mg/kg was the most effective drug giving a greater than 97% reduction in egg output six months after treatment; combined treatment with niridazole 25 mg/kg and metrifonate 10 mg/kg gave a reduction of greater than 92% and metrifonate 10 mg/kg alone a ...19836401550
[demonstration of an original process of asexual reproduction in schistosoma haematobium].the study of development of a malagash strain of schistosoma haematobium in bulinus obtusispira reveals two original processes in asexual reproduction: (a) the existence of an evolutive dimorphism of the secondary sporocysts: - an important secondary sporocyst population, localized mainly in the foot, produces daughter sporocysts (order iii); - a minor secondary sporocyst population, localized mainly in the digestive gland, produces cercariae. (b) a part of secondary sporocysts which, after leav ...19836405998
synergy of concurrent low dose oxamniquine and praziquantel in schistosomiasis. 19836412867
preliminary identification of a tumor-associated glycoprotein in bilharzial bladder cancer urine.a tumor-associated antigen was preliminarily identified in urine from bilharzial (squamous-cell carcinoma) bladder cancer patients. monospecific rabbit antisera were made by immunization with concentrated bladder cancer urine and exhaustive absorption with insoluble normal human serum and urine. the urine tumor-associated antigen was identical to an antigen from 3m kcl bladder tumor extract by immunodiffusion. the antigen in urine was found in nine of 10 bladder cancer patients and was absent fr ...19836413432
acute schistosomiasis (katayama fever). 19846419865
excretion of ecdysteroids by schistosomes as a marker of parasite infection.ecdysteroids produced by schistosomes are released in biological fluids of infected hosts. in the sera, the concentration of ecdysteroids correlates with the permissiveness of the host to schistosome infection and its detection is available in the absence of positive parasitological tests. in the urine, ecdysteroid concentration decreases markedly after chemotherapy. 20-hydroxyecdysone and its epimer were identified in the urine of infected patients using mass spectrometry. these data demonstrat ...19846427004
precipitates found around schistosoma haematobium eggs from human urine prior to circumoval precipitin test.schistosoma haematobium eggs were recovered in urine from schoolchildren in mwachinga village, kwale district, kenya. the surface of the eggs showed a pattern similar to that observed in a circumoval precipitin (cop) test. observed precipitates were removed by treatment of the eggs with pepsin, but were not affected by trypsin. similar precipitates occurred after incubating the pepsin-treated eggs with urine supernatants from the same children. attempts were made to identify the components that ...19846442551
dynamics of schistosoma haematobium infection in a gambian community. i. the pattern of human infection in the study area.the roles of some of the factors thought to be responsible for the characteristic relationship between age and the intensity and prevalence of schistosoma haematobium infection have been investigated. in this initial report a study population in an area of intense infection is described, as are the methods used. subsequent papers report the effect of interrupting transmission with molluscicide in part of the area and compare changes in egg count in this treated area with changes in an area where ...19846464109
dynamics of schistosoma haematobium infection in a gambian community. ii. the effect on transmission of the control of bulinus senegalensis by the use of niclosamide.niclosamide was used to interrupt transmission of schistosoma haematobium by bulinus senegalensis in seasonal rainwater pools for a period of three years. snail populations were progressively reduced to approximately 1% of the numbers in untreated pools. there was little or no evidence of acquisition of new infection by children in the area during the period of intervention. the intensity of infection in a cohort of children initially under 10 years old followed for three years fell by more than ...19846464110
dynamics of schistosoma haematobium infection in a gambian community. iii. acquisition and loss of infection.during a three-year period of effective control of schistosoma haematobium transmission by molluscicide application the mean number of s. haematobium ova passed by subjects in the treated area fell in an exponential manner which suggested that the mean life span of the worm was 3.4 years. parallel observations were made in a similar but untreated area. a comparison of the observations in these two areas suggested that in the untreated area subjects of all ages acquired infection during the cours ...19846464111
time of collection of specimens for schistosoma haematobium egg counts. 19846464121
comparative trial of oltipraz versus praziquantel in the treatment of urinary schistosomiasis in the gabon.the efficacy of oltipraz as a schistosomicidal drug was investigated in gabonese children suffering from urinary schistosomiasis in the dosages of 1 x 25 mg/kg body weight, 1 x 35 mg/kg body weight, and 2 x 20 mg/kg body weight and compared to praziquantel, 2 x 30 mg/kg body weight. the study was undertaken in 165 patients, and follow-up investigations were carried out 6 weeks and 12 weeks after treatment. oltipraz showed less efficacy compared to praziquantel when dosages of 1 x 25 and 1 x 35 m ...19846464191
comparative study of oltipraz versus praziquantel for treatment of schistosomiasis with intestinal manifestation in the gabon (schistosoma intercalatum and s. haematobium).158 school children from lambarene and its surroundings suffering from intestinal manifestations of schistosomiasis due to schistosoma intercalatum, schistosoma haematobium, or mixed infections were randomly allocated to patient groups to be treated with oltipraz and praziquantel respectively. oltipraz was tested in three dosage regimens, i.e., 1 x 25 mg/kg, 1 x 35 mg/kg, and 2 x 20 mg/kg and compared to 2 x 30 mg/kg praziquantel in each of the treatment groups. 45 days and 90 days after treatme ...19846464192
spontaneous nephrocolic fistula: causal association with urinary bilharziasis. 19846467362
cancer in iraq: seven years' data from the baghdad tumour registry.the relative frequency, by age, sex and site, of the malignant tumours notified to the baghdad cancer registry for the period 1976-1982 is presented. the pattern of cancer occurrence resembles that seen in other middle-eastern populations in the frequency of respiratory cancer and lymphomas, and the apparent deficit of cervix cancer. cancer of the urinary bladder is the dominant tumour, the majority being squamous-cell carcinomas, and the occurrence of this type is associated with histological e ...19846469397
treatment of bilharzial obstructive uropathy with praziquantel. 19846470535
the ultrastructure of the tegument of adult schistosoma haematobium.the ultrastructure of the tegument of schistosoma haematobium was examined using scanning and transmission electron microscopy. the surface of the male worm is characterized by numerous raised tubercles bearing apically directed spines. the female in contrast to the male is cylindrical and relatively smooth. details of oral and ventral suckers are given. the use of uranyl acetate as a tertiary fixative and en bloc stain has revealed the heptalaminate nature of the outer membrane. tegumental mito ...19846472886
the part played by the stroma in carcinogenesis. 19846473056
the oral treatment of urinary schistosomiasis in egyptian patients with 'oltipraz'.oltipraz was given in a daily dose of 1.5 gm for two days to 40 patients with haematobiasis. cure rates of 92.5% and 82.5% were obtained after two and six months follow-up examinations. a high proportion of egg-reduction of 97% and 98% was obtained in 'egg-positive' cases. clinical and biological tolerance of patients to the drug was excellent. the drug is easy in administration, given orally and with minimal side effects.19846474558
single-dose metrifonate for the treatment of schistosoma haematobium infection in an endemic area of zimbabwe.the excretion of schistosoma haematobium eggs by school children in an endemic area of zimbabwe was studied for 16 weeks following a single oral dose of 10 mg/kg body weight metrifonate. by 16 weeks, 40.7% of the children had ceased excreting eggs. the mean reduction in egg excretion was 75.1%, but over half the children showed a greater than 90% reduction. of the treatment failures, the majority showed less marked or transient reductions in egg excretion, though evidence suggested that 17.5% of ...19846476204
identification of diethylene glycol in sera from egyptian children by frequency-pulsed electron-capture gas-liquid chromatography.sera taken from fifteen patients (from kerdasa village near cairo, egypt) infected with schistosoma haematobium, with eggs present in the urine, were studied by frequency-pulsed electron-capture gas-liquid chromatography (fpec-glc). some of the patients were treated with metrifonate and again studied by fpec-glc. diethylene glycol was detected in the sera of untreated patients infected with s. haematobium. this compound was identified by negative chemical ionization and electron-impact mass spec ...19846480778
[bilharziasis of the juvenile urinary tract]. 19846482188
[comparative efficacy of oltipraz (1 dose, 30 mg/kg) and the combination of niridazole (25 mg/kg) and metrifonate (10 mg/kg) against s. haematobium].pugh (1978) and teedsale et al. (1980) showed that an associated single dose of metrifonate (12.5 mg/kg) plus niridazole (25 mg/kg) gave good results on schistosoma haematobium: the egg-reduction percentage ranged between 84.7 and 91.2. in niger, we compared the effects of this medication to oltipraz in a single dose (30 mg/kg). we selected a dosage of 10 mg/kg of metrifonate and 25 mg/kg of niridazole. this trial was carried out during the minimal transmission period. --109 adults (greater than ...19846482729
pathology of bilharzial bladder cancer.retrospective review of bladder carcinoma at this institution has revealed a high incidence of squamous cell carcinoma associated with bilharzia infection as has been found in other mideast and african countries. associated inflammatory and epithelial metaplastic changes were commonly noted and apparently represent early changes in the development of carcinoma, particularly in view of the progression from squamous metaplasia to in situ and infiltrating carcinoma observed in both bladder and uret ...19846483922
metrifonate in pregnancy. 19846485071
an evaluation of quantitative techniques for schistosoma haematobium eggs in urine preserved with carbolfuchsin.the objective of this study was to determine a suitable method for quantitating schistosoma haematobium eggs in urine specimens preserved in carbolfuchsin. using a 0.002% carbolfuchsin-phenol-alcohol solution as a stain/preservative for urine obtained from 30 patients infected with s. haematobium, we compared egg counts obtained with four quantitative techniques: nytrel filtration, nuclepore filtration, suction filtration and centrifugation. centrifugation gave statistically higher values than a ...19846486294
sensitivity and specificity of reagent strips in screening of kenyan children for schistosoma haematobium infection.the reliability of using urinalysis reagent strips, which semi-quantitatively measure hematuria and proteinuria, to correctly select urine specimens found by microscopy to have schistosoma haematobium eggs was studied in 359 previously unscreened kenyan primary school children. the presence of and degree of hematuria and proteinuria were highly correlated with the presence of s. haematobium eggs and with egg counts in urine specimens. hematuria was more strongly correlated with s. haematobium eg ...19846486295
a tool at hand for the screening of schistosoma haematobium infections. 19846489232
schistosomiasis and praziquantel. 19846497212
urinary schistosomiasis: a report of four cases and a review.urinary schistosomiasis is a common cause of hematuria in tropical regions, where it most often affects teenage boys. children presenting with hematuria in the developed world are usually considered to have bacterial cystitis or a structural lesion and are investigated and treated accordingly. the authors report on a family recently returned to canada from nigeria in which all four children had urinary schistosomiasis. nocturnal enuresis was the presenting symptom in the index case; this patient ...19846498688
schistosoma haematobium: amoscanate and adult worm ultrastructure.amoscanate, when administered orally as an aqueous or "formulated" preparation, induced pronounced ultrastructural abnormalities in male and female schistosoma haematobium. higher dose levels of the aqueous suspension (300 mg/kg body wt) had to be administered to achieve the full range of effects induced by formulated doses of 2.5-8 mg/kg body wt. worms were recovered from hamsters between 1 and 120 hr after treatment. although the amount of amoscanate-induced damage varied considerably between ...19846500001
carcinoma of the uterine cervix and schistosomiasis in west africa.schistosomiasis of the uterine cervix is the most common form of genital schistosomiasis, and is most frequently associated with schistosoma haematobium infection. cervical schistosomiasis assumes medical importance because clinically it may be mistaken for cervical malignancy. additionally, it has been proposed that cervical schistosomiasis may lead to the development of cervical carcinoma. in this regard, a patient having squamous cell carcinoma of the cervix in association with cervical schis ...19846500378
the effect of a single dose of metrifonate on schistosoma haematobium infection in egyptian school children.egyptian school children infected with schistosoma haematobium and treated with a single dose of metrifonate, 10 mg/kg body weight, had a marked reduction in urine egg counts reaching 90% during a 30-week follow-up. while cure rate was higher among lightly infected persons, percentage reduction in egg counts was greater among the heavily infected. after a summer period of probable high risk exposure reinfection rate in those children who were treated and cured was 4.7% as compared to 6% in previ ...19846507729
is planorbarius metidjensis compatible with schistosoma haematobium and s. bovis?on the basis of laboratory snail infection experiments it is concluded that planorbarius metidjensis is unimportant in the epidemiology of schistosoma haematobium in north west africa. 410 p. metidjensis spain were exposed to 8 isolates of s. haematobium from ghana, kenya, madagascar, mauritius, morocco, tanzania, south africa and sudan. 50 p. metidjensis morocco and 50 p. metidjensis algarve were exposed to s. haematobium morocco. all infections failed to develop to maturity. serial sections of ...19846509700
the effect of diurnal fluctuating temperature on the development of s. haematobium in b. truncatus. 19846512298
[bilharziasis of the urinary tract]. 19846516352
early schistosomiasis in a young immigrant. 19846517814
[anatomicopathological aspects of genital bilharziasis in women].the localisations of the genital bilharziosis of the woman are not very known. however, they are responsible of many functional sequelae: pelvic aches, menstrual troubles, aberrant nidations, spontaneous abortions, permanent sterilities. from 43 anatomic taking investigated from 1971 to 1982 and from the literature they have collected, the authors successively study the localisations of the genital bilharziosis on ovary (21 %), uterine tube (16 %), uterine cervix (42 %), vulva, vagina and clitor ...19846521631
[a case of urinary schistosomiasis in a japanese male].urinary schistosomiasis is an endemic disease mainly distributed in most of africa and southwest asia, and caused by infestation with schistosoma haematobium. the case presented here was a 33-year-old japanese male who had suffered from schistosomal infestation in the endemic area, and diagnosed as urinary schistosomiasis by detection of schistosoma haematobium ova in urine and specimens obtained by mucosal biopsy of the bladder. radiographic and endoscopic examinations revealed neither obstruct ...19846524558
[acute bilharzial cor pulmonale due to schistosoma mansoni].the authors report a cause of acute cor pulmonale caused by schistosoma mansoni bilharziosis. the clinical feature was a collapse with right ventricular failure following a delivery. the hemodynamic exploration showed a pre-capillary and supra-systemic pulmonary hypertension. the histopathologic study in post-mortem showed pulmonary lesions of fibrosis endarteritis with granulomatosis reaction round many eggs of schistosoma mansoni. the authors discuss the frequency of various anatomic lesions ( ...19846525724
biology, life-tables, and intrinsic rates of increase of bulinus globosus morelet and lymnea natalensis kraus (gastropoda: pulmonata)--the snail intermediate hosts of schistosoma haematobium and fasciola gigantica, respectively, in southeastern nigeria.two tables and a figure are used to present the epidemiological and epizoological particulars of bulinus globosus and lymnaea natalensis, the intermediate hosts of schistosoma haematobium and fasciola gigantica in southeastern nigeria. possible ways of reducing the populations of these intermediate hosts are seen in the combined application of chemical agents and environmental shaping.19846529436
[an unusual case of hematuria].the author describes a unusual case of haematuria from schistosoma haematobium and dispute the modalities of diagnosis and therapy.19846535136
the serum alkaline phosphatase in schistosomiasis. 19846536462
immune responses and immunoregulation in relation to human schistosomiasis in egypt. ii. cimetidine reversal of histamine-mediated suppression of antigen-induced blastogenesis.the effect of histamine on cell-mediated immune responses of chronic schistosomiasis patients was tested by peripheral blood mononuclear cell (pbmn) reactions to phytohemagglutinin-p (pha) and soluble schistosomal antigenic preparations derived from eggs (sea) or adult worms (swap). pbmn responses to pha were suppressed by exogenous histamine (10(-5)m), and the addition of cimetidine (cim) (10(-4)m), an h2-receptor antagonist, reversed this suppressive effect. histamine primarily suppressed pbmn ...19846540282
cytologic diagnosis of schistosomiasis in routine urinary specimens. a case report.a voided urine specimen from a 29-year-old male living in new york was sent for cytologic study, which revealed five schistosome ova, two with terminal spines, and one free miracidium in a cytocentrifuge specimen. the patient, who had been in west africa three years earlier, underwent cystoscopy, with the finding of bladder mucosal ulcerations. subsequent cytologic specimens, bladder biopsy and wet-mount preparations established a diagnosis of schistosoma haematobium infection, which was treated ...19836575543
metrifonate in the treatment of schistosoma haematobium infection. 19836580560
an uncommon cause of hematuria: the patient's story. 19846583509
[clinical aspects and therapy of schistosomiasis].among 810 parasitologically examined persons (1981) 277 (34%) showed positive findings. the high percentage of parasitisation in foreigners (86%) is to be explained by the in most cases aimed transfer of these patients (215 of the 810 persons). affection with schistosoma was recognized in 51 patients at the age of 17-47 years (means = 21.86), without africans, and stood in the 3rd place of the distribution of frequency of the heterogeneous parasitoses. 49 of these patients came from mozambique, ...19836613196
[effectiveness of 3 doses of metrifonate in the treatment of urinary bilharziasis in senegal]. 19836617452
effect of chemotherapy and reinfection on ige-containing and igg-containing circulating immune complexes, serum ige and ige antibodies in patients chronically infected with schistosoma mansoni and schistosoma haematobium.the effect of chemotherapy and reinfection on circulating immune complexes (cic), serum ige, and parasite-specific ige antibodies was studied in patients concomitantly infected with schistosoma mansoni and schistosoma haematobium. before chemotherapy ige- and igg-containing cic were present in high concentrations in all patients and ige antibodies to s. mansoni and to s. haematobium in almost 80% of the cases. serum ige was excessively high (median 4,900 ku/1), but decreased to half of its initi ...19836618683
[are schistosomiases debilitating diseases?]. 19836622414
studies on schistosomiasis in taiz province, yemen arab republic.infection with both urinary and intestinal schistosomiasis is prevalent with patchy distribution in taiz province, southwest yemen arab republic. schistosoma haematobium with a prevalence as high as 90% was found in the western, southern, and northern parts of the province. among school children the overall prevalence was 37%. infection rates did not differ significantly among various age and sex groups. three species of bulinus--b. beccarii, b. truncatus, and b. wrighti--have been found in the ...19836625057
control of schistosomiasis in large irrigation schemes by use of niclosamide. a ten-year study in zimbabwe.the development of chemical control strategies, and regular assessments of snail populations over a 10-year period, has resulted in reduced incidence of disease and the efficient use of niclosamide by competent administrators. full knowledge of all water-bodies, strict surveillance programs, and timing of dam treatments have minimized the chances of snails becoming infected within a 380-km2 area. the scheme is now entirely estate-run and administered. in spite of soaring prices, particularly tho ...19836625058
efficacy of amoscanate against experimental schistosomal infections in monkeys.the antischistosomal activity of oral doses of amoscanate (4-isothiocyanato-4'-nitrodiphenylamine) was determined in infected cebus apella (capuchin monkeys) and macaca mulatta (rhesus monkeys). in c. apella infected with schistosoma japonicum or s. mansoni an initial dose of 10 mg/kg body weight did not alter fecal egg counts, but a subsequent dose of 25 mg/kg markedly reduced both egg counts and worm burdens; in animals infected with s. haematobium, a single dose of 25 mg/kg of amoscanate was ...19836625061
a field trial using praziquantel (biltricider) to treat schistosoma mansoni and schistosoma haematobium infection in gezira, sudan.a field trial was conducted in the gezira, sudan, to evaluate the acceptability and efficacy of praziquantel, a new schistosomicide. in one arab village 350 patients with schistosoma mansoni were randomly assigned to two treatment groups and given 1 x 40 mg kg-1 (group a) or 2 x 20 mg kg-1 given four to six hours apart (group b). in two small settlements (camps) 2 km distant from the arab village 38 patients with s. mansoni and 43 with concurrent s. mansoni and s. haematobium infections were giv ...19836625729
schistosomiasis in swaziland--a comparative study of three irrigated estates.the prevalence of schistosomiasis and the distribution of the snail intermediate hosts on three adjoining irrigated estates in the lowveld of swaziland was investigated. the prevalence rates of schistosoma haematobium and s. mansoni among estate employees was lower than anticipated and there was a marked difference between the prevalence rates of s. mansoni between estates. the reasons for this and the influence of water supplies and agricultural practice on the prevalence of schistosomiasis are ...19836630996
colorectal schistosomiasis. endoscopic polypectomy.the role of colonoscopic polypectomy for schistosomal polyps was studied. the results showed that, in spite of the large number of polyps, a total of 404 polyps were removed from 20 patients. the procedure is feasible with minimal complications. a marked reduction of rectal bleeding occurred in half the patients, and the remaining half had minimal symptoms. colonoscopic polypectomy gives equal results to colonic excision for schistosomal polyps.19836641458
schistosoma mansoni, s. japonicum, s. haematobium: glycogen content and glucose uptake in parasites from fasted and control hosts.the glycogen content of male and female schistosoma mansoni has been measured in flukes from normally fed hosts and those from fasted hosts. in infections from both the mouse and the hamster, a significant reduction in schistosomal glycogen of males is seen hours after food is withdrawn from the host. reductions in protein content of the schistosomes were only observed in hamster infections fasted at least 72 hr. the livers of infected mice not only decrease in size during fasting, but there is ...19836641897
[bacterio-parasitic interactions. enterobacteria and schistosomes (salmonella - schistosome association)].the description of a case imported from chad of an association of salmonella typhi - schistosoma haematobium and, in this connection, a new revised general account. the association salmonella-schistomas is wide-spread. it corresponds to a salmonello - schistosomo - micro - association by the fixation of precise bacteria in the case of a bacteriemia on the cutaneous surface of male schistosomes in clearly defined places. these salmonella constitute a permanent antigenic solicitation and they are ...19836645880
urinary schistosomiasis in the sahelian region of the senegal river basin.two dams are projected for the senegal river, west africa, for hydroelectric power, anti-salt intrusion and for provision of a dependable supply of freshwater year-round. this study was to ascertain the geographic distribution of schistosomiasis, its snail hosts and the potential transmission sites before the construction of the two dams. no intestinal schistosomiasis was found in the area investigated, the sahelian region. villages in the delta, as well as those situated by the senegal river in ...19836649050
immunodiagnosis of schistosomiasis haematobium and schistosomiasis mansoni in man. application of crude extracts from adult worms and cercariae in the iha and the elisa.the antibody responses of patients infected with s. haematobium or s. mansoni were investigated in an indirect hemagglutination test (iha) and an enzyme linked immunosorbent assay (elisa) using crude extracts of cercariae and adult worms of s. haematobium and s. mansoni, and of adult worms of s. japonicum. patients were africans from endemic areas, as well as europeans who had acquired their infection relatively recently. although the iha showed a similar pattern of antibody responses as the eli ...19836649986
[current status of urinary bilharziasis in the population of the shores of lake de guiers (northern senegal)]. 19836653330
xanthogranulomatous pyelonephritis with bilharzial ureteric obstruction. 19836653472
hepatic fibrosis in schistosoma haematobium-infected mice.swiss mice were exposed subcutaneously to 270 to 500 schistosoma haematobium cercariae and killed 13 to 52 weeks later. less than 10% of applied cercariae were recovered as worms, and the rate of oviposition by adult worm pairs was generally low. however, the adult worms survived well, the females contained an average of 56 eggs one year after infection, and numerous mature eggs were present in the tissues. all worms were located in the portal venous system. s. haematobium eggs in the liver elic ...19836659047
treatment with praziquantel in a patient with schistosomiasis and chronic renal failure.the pharmacokinetics of praziquantel in a uraemic patient, infected with schistosoma haematobium, undergoing haemodialysis, was studied by repeated analyses of serum, urine and dialysis fluid. the results indicate the possibility of treating advanced cases of infection with s. haematobium with the normally recommended doses.19836659048
day-to-day variation and circadian rhythm of egg excretion in urinary schistosomiasis in the sudan.the daily variation of urinary excretion of schistosoma haematobium and schistosoma mansoni ova was assessed in a group of 24 sudanese schoolboys using the filtration trypan blue staining technique. an intra-class correlation coefficient of r = 0.88 indicated a surprisingly low daily variation of excretion of s. haematobium ova. all patients with a median egg output of at least 100 ova per 10 ml also voided s. mansoni ova in the urine. the daily variation of s. mansoni ova was slightly greater t ...19836660966
concomitant infection with filariasis and schistosomiasis in an endemic area in sharkyia governorate, egypt. 19836663104
prepatency of schistosoma haematobium in snails at different constant temperatures. 19836663114
[treatment of 700 cases of bilharziasis with the new drugs oxamniquine, oltipraz, praziquantel].the authors study the results of a treatment of 700 cases of bilharziasis seen in paris and in two foci in togo, by oxamniquine, oltipraz or praziquantel. the three drugs are well tolerated; only a few mild side-effects were reported such as discomfort, nausea, headaches (two cases of acrodynia with oltipraz ). the three drugs are very efficacious in the case of schistosomiasis mansoni (85,5% success rate with oxamniquine, 92,9% with praziquantel, from 76,5 to 92% with oltipraz depending on the ...19836673843
[mass treatment of schistomsoma haematobium bilharziasis in the member states of the organization for coordination of the campaign against endemic diseases in central africa].the authors analysed the results of the control of schistosoma haematobium bilharziasis in two central african countries, the congo and the cameroun . these results demonstrated: --the feasibility of mass screening by filtering urine; --the acceptability and efficacy of new antibilharzian drugs, praziquantel and oltipraz . with the aim of improving the cost/effectiveness ratio of these campagnes and taking into account the health requirements which exist and/or are desired by the population, the ...19836673844
identification of species-specific and gender-specific proteins and glycoproteins of three human schistosomes.species-specific and gender-specific polypeptides of schistosoma haematobium, schistosoma japonicum, and schistosoma mansoni have been identified. proteins of these schistosomes were metabolically labeled in vitro with 35s-methionine and their total proteins, concanavalin-a binding glycoproteins, released (shed or secreted) proteins, and released glycoproteins compared by two-dimensional polyacrylamide electrophoresis. many of the released proteins were glycosylated, and most of the synthesized ...19836674449
identification of sex of schistosome larval stages.sex of schistosoma mansoni cercariae was identified by a c-banding technique; interphase nuclei of females exhibited w-chromatin (heterochromatin of the w chromosome) whereas those of males did not. similar sexual dimorphism was also shown in nuclei of s. mansoni miracidia, sporocysts, and adult worms. cercariae of the following schistosomes could not be sexed by examination of nuclei after the c-band technique: s. japonicum, s. haematobium, and schistosomatium douthitti . the method presented w ...19836674459
man-made dams acting as sources of bilharziasis in onganga village, kanyaluo location, south nyanza. 19836676096
vesico-ureteric reflux in urinary bilharziasis (observation in zambia). 19836679157
parasitic infections, anaemia and nutritional status: a study of their interrelationships and the effect of prophylaxis and treatment on workers in kwale district, kenya.a study was conducted between january and august 1979 on 150 male roadworkers in kwale district in the coastal lowlands of kenya. at the baseline examination 59% had hookworm (mean of 227 epg +/- 541), 38% had infections of schistosoma haematobium (mean 52 +/- 82 ova per 10 ml urine), 23% had a blood film positive for malarial parasites, 47% had anaemia (hb below 13g/dl), and 31% had a percentage weight for height below 80% of a reference value for healthy men. it was found that anaemia was sign ...19836679363
some factors affecting the hatchability of schistosoma ova and miracidial activity. 19836685161
[trial control by metrifonate chemotherapy of schistosoma haematobium in a dry savannah zone in upper volta].metrifonate (bilharcil) was administered in a dose of 7,5 mg/kg, four times at 3 weeks interval to all villagers, regardless of the result of parasite examination, in order to test this treatment of urinary schistosomiasis in a hyperendemic village. on the year following the treatment, three parasite surveys were carried out. they showed a decline in the prevalence and a decrease in number of eggs excreted in the urine. the decrease rate was 91% to 94% in the 10-14 years group, the group with th ...19836685810
schistosoma mansoni, s. haematobium, and s. japonicum: identification of genus-, species-, and gender-specific antigenic worm glycoproteins.immunoreactive glycoproteins of schistosoma mansoni, s. haematobium, and s. japonicum adult worms which are genus-, species-, and gender-specific, or react with sera of patients infected with other parasites, have been identified. schistosomes were metabolically labeled with [35s]methionine and the concanavalin-a binding glycoproteins that were immunoprecipitated with sera of patients infected with one of three species of schistosoma or trichinella spiralis, taenia solium, echinococcus granulosu ...19846692879
the prepatent period and cercarial production of schistosoma haematobium in bulinus truncatus (egyptian field strains) at different constant temperatures.the developmental time of schistosoma haematobium in bulinus truncatus snails (field strains) was determined in the laboratory at different constant temperatures between 18 and 32 degrees c. the basic relationship between the length of the minimum prepatent period (y, in days) and the temperature (x, in degree c) is given by the hyperbolic formula y = 295/(x-15.3), 15.3 being the theoretical "developmental null point" and 295 the constant time-temperature product. the shortest prepatency was 17- ...19846695537
urinary calculus in zambia: its incidence and relationship to schistosoma haematobium infection and vesicovaginal fistula.radiological, cystoscopic and histological observations were made on 41 cases of urinary stones in a hospital in zambia. the results of biochemical analysis of 31 of these stones are presented. the possible role of schistosoma haematobium in the causation of urinary stones has been analysed; associated schistosomiasis was diagnosed in 17 cases (41.4%). it is concluded that there is no significant causal association between the two disorders and urolithiasis is an uncommon disease in zambians.19846697105
field studies on bulinus senegalensis muller and the transmission of schistosoma haematobium infection in a gambian community.seasonal changes in populations of bulinus senegalensis were studied in temporary pools on the senegambian plateau. the first snails to appear had survived aestivation and had a mean height of 3 mm. thereafter two patterns of change in snail numbers and size were observed probably related to differences between pools in snail mortality rates. the prevalence of patent schistosome infections appeared to be related to the inferred differences in snail mortality rates. the prevalence and intensity o ...19846710598
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