| sensitivity of gentamicin-resistant enterobacteriaceae to cefamandole and cefoxitin. | a collection of gentamicin-resistant enterobacteriaceae strains was significantly more resistant to cefamandole than a species-matched collection of gentamicin-sensitive organisms. cefamandole and gentamicin resistance could be simultaneously transferred by conjugation from four different species, citrobacter freundii, escherichia coli, klebsiella pneumoniae and serratia marcescens, to a recipient e. coli strain. plasmids specifying linked resistance to cefamandole and gentamicin are thus common ... | 1979 | 456076 |
| [phagocytic-activity in high risk patients of a surgical intensive care unit (author's transl)]. | the in vitro phagocytic activity from pmnl against eight different klebsiella strains, isolated from clinical material, was investigated and the k-index calculated for fifteen patients from a surgical intensive care unit. the hemagglutinating antibody titers against the test strains, as well as the serum concentrations of igm, igg, c3 and c4 were also determined. at the time of the investigation all patients had symptoms of a severe general infection. there could be no decrease in the phagocytic ... | 1979 | 457188 |
| [clinical studies on pc-904 in biliary tract diseases (author's transl)]. | the clinical effects of pc-904, a new semisynthetic penicillin, were studied in patients with biliary tract diseases, and the results were as follows: 1) pc-904 showed an average peak serum level of 40.7 +/- 11.6 microgram/ml 2 hours after an intravenous drip infusion of 1 g of the agent. the biliary level showed a peak value of 126.5 +/- 85.4 microgram/ml 2 hours to 3 hours after the infusion. 2) isolated organisms from bile before the treatment were e. coli, klebsiella, proteus, pseudomonas, e ... | 1979 | 459091 |
| [carcinoembryonic antigen (cea) and cea-like activities in ascites and pleura-effusions (author's transl)]. | carcinoembryonic antigen (cea) was assayed in 18 samples of non-malignant and 21 samples of malignant effusions. in 95% of benign effusion cea activity was found within normal limits and increased only in one case of klebsiella pneumonia. in 57% of the 21 malignant effusions cea levels were elevated and in 4 cases elevated titers were first indications of the malignancy of the effusion. in some cases remarkable differences between serum titer and effusion titer were found. combined measurement o ... | 1979 | 459372 |
| in vitro activity of mezlocillin and its related compounds against aerobic and anaerobic bacteria. | a total of 900 clinical isolates of aerobic (462 isolates) and anaerobic (438 isolates) bacteria were tested against mezlocillin in comparison with other penicillins, and the aerobes were also tested against cephalothin, cefoxitin, and cefamandole. among penicillins, mezlocillin was the most effective against escherichia coli, klebsiella pneumoniae, salmonella species, pseudomonas aeruginosa, and bacteroides fragilis. mezlocillin was more effective than cephalothin against klebsiella pneumoniae. | 1979 | 464578 |
| comparison between agar and broth minimum inhibitory concentrations of cefamandole, cefoxitin, and cefuroxime. | the in vitro susceptibility to cefamandole, cefoxitin, and cefuroxime of clinical isolates of streptococcus faecalis, klebsiella, and indole-positive proteus was assayed using minimum inhibitory concentration (mic) determinations in broth and on solid media. it could be demonstrated that the agar dilution mics obtained when s. faecalis was tested against cefuroxime and when indole-positive proteus strains were tested against cefamandole tended to be considerably lower than those obtained with th ... | 1979 | 464588 |
| antibiotics in pyelonephritis. | | 1979 | 467068 |
| adherence of enterobacteriaceae to human buccal cells. | a preliminary examination has been made of the adherencae isolated from sputa. the radioadherence method was found to correlate well with the conventional light-microscope adherence technique. saturation of buccal-cell binding sites with bacteria occurred when less than 10% of the buccal-cell surface was occupied. the adherence of enterobacter aerogenes to buccal cells was impaired by the prior adherence of bacilli of either the same strain, or of a strain of klebsiella pneumoniae. | 1979 | 469931 |
| gram-negative bacteremia. two cases in adults with chronic otitis media. | chronic otitis media was the cause of septicemia in two hospitalized men. the organisms involved, k pneumoniae and b fragilis, are not usually associated with primary infections of the middle ear and would not have been traced to this site had proper cultures not been performed. in adults, the true incidence of bacteremia arising from the middle ear may be higher than suspected. | 1979 | 471850 |
| multifocal malignant melanoma of the esophagus. | we have described a case of primary melanoma of the esophagus in an asymptomatic patient. the tumor presented as a multinodular filling defect on a routine barium swallow. the distal esophagus and a proximal portion of the stomach were resected. the patient died ten days postoperatively of klebsiella sepsis. grossly, the surgical specimen showed multiple polypoid tumors which arose from separate pigmented areas shown microscopically to be melanoma in situ. by electron microscopy, the tumor cells ... | 1979 | 472796 |
| faecal pollution of surface waters in jakarta. | profuse numbers of enterobacteriaceae were found in samples of surface waters from the ciliwung river and adjoining canals which criss-cross metropolitan jakarta and are used widely for domestic purposes by the poorer sections of its population. 15 of the 20 specimens gres e. coli, klebsiella were isolated from seven and citrobacter from four. using enrichment culture procedures, salmonella sp. were grown from 10 (48%) of 21 water samples examined, and 12 (63%) of aquatic sediments collected at ... | 1979 | 473327 |
| storage of microtiter plates for antimicrobial susceptibility tests. | microdilution susceptibility tests are being performed routinely and in increasing numbers in many clinical laboratories. microtiter plates for these assays are usually prepared in large batches and stored frozen until needed. studies were performed to investigate the stability at -20c and at -70c of ampicillin, carbenicillin, ticarcillin, gentamicin, tobramycin, amikacin, chloramphenicol, and cephalothin, using enterobacter aerogenes, proteus mirabilis, proteus vulgaris, escherichia coli, pseud ... | 1979 | 474606 |
| the structure of the capsular polysaccharide of klebsiella k-type 31. | the structure of the klebsiella k31 capsular polysaccharide has been elucidated by periodate oxidation, methylation analysis, characterization of oligosaccharides obtained by partial, acid hydrolysis, and proton magnetic resonance. the polymer consists of pentasaccharide repeating-units having the following structure (1). | 1979 | 476723 |
| animal model of neutropenia suitable for the study of dual-phagocyte systems. | when two sets of phagocytic cells participate simultaneously in the inflammatory process and bacterial killing, the relative contribution of each cell type is difficult to ascertain. the use of cell-specific antibody will permit selective depletion of one phagocyte population. we describe an experimental model of granulocytopenia which utilizes the immunoglobulin g fraction of an antigranulocyte serum. this material markedly depleted circulating polymorphonuclear leukocytes (pmn); within 2 h aft ... | 1979 | 478637 |
| the sensitivity of gentamicin-resistant gram-negative bacilli to cefotaxime, other cephalosporins and aminoglycosides. | the sensitivities of 80 gentamicin-resistant gram-negative bacilli to cefotaxime, cefuroxime, cefoxitin, cefamandole, cefazolin, tobramycin, netilmicin and amikacin were determined. amikacin was the most active amino-glycoside. however, the percentage sensitivity to cefotaxime of most of the species was higher than, or equal to any of the other antibiotics tested. cefotaxime was particulary active against providencia spp., serratia spp., klebsiella spp., and pseudomonas maltophilia, being 16 to ... | 1979 | 478651 |
| the production of antisera to the klebsiella capsular antigens. | | 1979 | 479055 |
| influence of oxygen tension on nitrate reduction by a klebsiella sp. growing in chemostat culture. | at dissolved oxygen tensions of 15 mmhg (2 kpa) and below, nitrate-limited continuous cultures of klebsiella k312 synthesized nitrate reductase (nr) and nitrite reductase (nir) and excreted ammonia. under anaerobic conditions over 60% of the nitrate-nitrogen utilized was excreted as ammonia. in contrast, carbon-limited cultures excreted nitrite at dissolved oxygen tensions of 15 mmhg or below and synthesized nr but not nir. ammonia repressed neither nr nor nir synthesis. these observations indic ... | 1979 | 479838 |
| [steroid therapy for infectious diseases--indications and methods of administration]. | | 1979 | 480657 |
| [germinal change and its significance in the hospital (author's transl)]. | to receive objective informations about clinically supposed difference of bacteria spectrum in hospital infections within the last 20 years, we made statistical comparatively investigations between varying periods and in different fields. in the whole material of the medical department we found an increase of proteus, pseudomonas and klebsiella (p = 0,01%) and an increase of candida while staphylococci, streptococci, pneumococci, clostridium and meningococci have clearly decreased. in the depart ... | 1979 | 484110 |
| [a study of the action of sodium chlorate on strains of nitrate reducing soil bacteria (author's transl)]. | fours strains of nitrate reducing bacteria isolated from soil were studied for their behavior towards chlorate. they are facultative anaerobes, except for bacillus megatherium (which is a strict aerobe) and they possess a nitrate reductase a. the growth of three strains of bacteria (klebsiella pneumoniae, b. licheniformis and micromonospora globosa) was slowed by sodium chlorate at a concentration of 0.06 to 0.1% while the other strain (b. megatherium) tolerated the cio3- well. the delay of bact ... | 1979 | 484991 |
| [detection and significance of histidine decarboxylase (hdc) in "klebsiella", "enterobacter" and "serratia" (author's transl)]. | a quick colorimetric procedure for detection of histidine decarboxylase (hdc) in cultures of klebsiella, enterobacter and serratia is described. only e. aerogenes could decarboxylate histidine (production of histamine). the interest of hdc test for differentiation of e. aerogenes from k. pneumoniae (especially urease negative strains) is discussed. | 1979 | 484995 |
| cyclitol utilization associated with the presence of klebsielleae in botanical environments. | bacteria of the tribe klebsielleae are capable of metabolizing the cyclitols myoinositol, sequoyitol, and pinitol, which are present in aqueous extracts of redwood. of the combined klebsiella isolates from clinical and environmental origins, 100% (138/138), 97% (34/35), and 86% (119/138) fermented inositol, sequoyitol, and pinitol, respectively. these compounds were also used as a sole source of carbon and energy by klebsiella. similar results were obtained with enterobacter isolates, but most o ... | 1979 | 485138 |
| [prevalence and transferability of the plasmid lac+ character in "klebsiella" sp. strains with "lac+-forte" phenotype]. | 36 strains of klebsiella sp. showing a strong lactose-positive phenotype were examined for presence of r factors and for ability to promote the transfer of character lac+; 10 of the 13 r+ strains were able to transfer lac+ character and 4 showed the presence of r-lac factors. transfer of r-lac factors from klebsiella sp. strains to salmonella typhi clinical isolates has also been obtained. | 1979 | 485592 |
| [identification and antibiotic-resistance of microbial strains isolated from urinary infections (author's transl)]. | during the year 1977, 1491 urine samples were taken from patients living in the "alta valle del tevere" (umbria, italy). the isolated microorganisms were examined and tested against 15 antibiotics. 535 samples (35.88%) were free from bacteria. among the 1095 isolates, 52.42% were gram-negative, 46.85% gram-positive, and only 0.73% fungi. the genera citrobacter, escherichia, proteus, pseudomonas, enterobacter, klebsiella, staphylococcus and enterococcus were identified. a high proportion of strai ... | 1979 | 485594 |
| aerobic and anaerobic bacterial flora in semen from fertile and infertile groups of men. | semen samples were collected by masturbation under asceptic conditions from men who had sired children within the past 6 mo (group a) and asymptomatic men attending an infertility clinic who had not sired children and whose wives were asymptomatic for infertility (group b). these 109 semen samples were analyzed and cultured for isolation of aerobic and anerobic organisms. overall, 68% of the specimens had positive bacterial cultures: 54% of the samples from group a were positive and 73% from gro ... | 1979 | 485650 |
| structural studies on the capsular polysaccharide from klebsiella serotype k64. | partial hydrolysis with acid, methylation analysis (including uronic acid degradation), smith degradation, and p.m.r. spectroscopy have been used to determine the primary structure of the capsular polysaccharide of klebsiella serotype k64. the hexasaccharide repeating-unit, which also contains one o-acetyl substituent, comprises a 4)-alpha-d-glcpa-(1 leads to 3)-alpha-d-manp-(1 leads to 3)-beta-d-glcp-(1 leads to 4)-alpha-d-manp-(1 leads to chain with a 4,6-o-(1-carboxyethylidene)-beta-d-glucopy ... | 1979 | 487363 |
| bacteriology of chronic respiratory disease of non-tubercular origin. | | 1979 | 489083 |
| low-velocity gunshot wounds to the maxillofacial complex. | a review of the past literature of gunshot wounds indicates that the clinical material deals mainly with high-velocity missile injuries from military experience. a series of 66 cases of low-velocity gunshot wounds to the maxillofacial complex at san francisco general hospital between 1971 and 1978 indicates a clinical difference between injuries caused by low-velocity as compared to previously reported high-velocity missiles. damage to vital structures resulting from missile injury to the maxill ... | 1979 | 490741 |
| [studies on in vivo activity of antibiotics in experimental pneumonia in rats. i. combination of ciclacillin and serratiopeptidase (author's transl)]. | | 1979 | 490898 |
| [results of the use of a new aminoglycoside antibiotic, sisomicin, in gram negative bacterial respiratory infections]. | clinical efficacy of a new aminoglycoside antibiotic, sisomicin, was evaluated in 14 patients with acute chest infections (12 cases with pneumonia and 2 with bronchitis). they were selected taking into account the isolation of sisomicin-sensitive gram-negative bacilli in a sputum specimen collected prior to therapy. local predisposing factors were present in 4 patients whereas general predisposing factors were present in 4 patients whereas general predisposing factors were recognizable in 9. kle ... | 1979 | 492551 |
| experimental embolization in kidneys: tissue concentration of antibiotics. | in 7 dogs renal arterial embolization was performed using the seldinger technique and an inflatable swan ganz balloon catheter. methyl methacrylate and butyl-2-cyanoacrylate were injected. 6 months later, the tissue concentration of cefazolin was measured in the embolized and contralateral kidneys and in serum 2 h after a short infusion of 1 h cefazolin. the concentrations in serum and homogenized kidney tissue were determined by means of the agar gel diffusion method. angiography showed no vess ... | 1979 | 494438 |
| evaluation of a pectin agar medium for isolation of yersinia enterocolitica within 48 hours. | a modified pectin agar medium was evaluated for the rapid isolation and presumptive identification of yersinia enterocolitica. of 118 isolates of enterobacteriaceae tested, only the 13y. enterocolitica and the three klebsiella oxytoca strains produced colonies that depressed and sank into the agar. yersinia enterocolitica was also easily identified in mixed cultures, even from inocula containing three times as many other enterobacteriaceae organisms as y. enterocolitica. the recovery of y. enter ... | 1979 | 495561 |
| klebsiella rhinoscleromatis: a clinical and pathogenic enigma. | rhinoscleroma is a chronic, slowly progressive, infectious disease of the respiratory tract that can produce disability and death, if untreated. once considered an anomaly in the united states, the disease is now seen more frequently in this country, owing to increased travel from endemic areas. this report presents a comprehensive review of the several types of therapy that have been published in the literature. the results of a clinical experiment are also presented. | 1979 | 503491 |
| a survey of the aerobic bacteria in the droppings of captive birds of prey. | fresh droppings were collected from six species of bird of prey (falconiformes and strigiformes). bacteriological examination revealed that the birds' digestive systems were colonised by bacteria found widely in other species of animals. throughout the survey no salmonella species were isolated. | 1979 | 504802 |
| mezlocillin in the therapy of serious infections. | mezlocillin, a new semisynthetic penicillin chemically related to ampicillin which is more active than carbenicillin against ps. aeruginosa, b. fragilis and strep. faecalis and which inhibits many klebsiella, was evaluated in the therapy of 34 episodes of infection in 26 patients. infection sites included pulmonary, urinary tract and tissue infections, including peritonitis. seven patients had bacteremia. clinical cures were achieved in 83 per cent and bacteria cures in 76 per cent of infections ... | 1979 | 507086 |
| in vitro activity of ly127935. | the activity of ly127935, a beta-lactam antibiotic of novel structure, was studied in vitro against facultative gram-negative bacilli, staphylococcus aureus, and bacteroides fragilis. the strains were recent clinical isolates, many of which were relatively resistant to other antibiotics. ly127935 exhibited striking activity against escherichia coli, klebsiella pneumoniae, enterobacter sp., proteus sp., serratia marcescens, and b. fragilis with median minimum inhibitory concentrations of less tha ... | 1979 | 507785 |
| [results of treatment with cefaclor, a new oral cephalosporin]. | | 1979 | 511065 |
| [experience with cefuroxime in pediatric field (author's transl)]. | having resistance to beta-lactamase-producing strains and showing resistance to not only cephalosporin resistant strains of e. coli and klebsiella but also to citrobacter, proteus and enterobacter, cefuroxime (cxm) was used in pediatric field for both fundamental and clinical studies. cxm was found to be a useful antibiotic in views of high clinical efficacy rate obtained and no side effect noted. as for the dose, the single dose of 25 mg/kg achieved sufficient blood levels. also in view of good ... | 1979 | 513298 |
| klebsiella infections in mares. | | 1979 | 516337 |
| meningitis and septicemia due to klebsiella ozaenae. | | 1979 | 517454 |
| alafosfalin, a new inhibitor of cell wall biosynthesis: in vitro activity against urinary isolates in japan and potentiation with beta-lactams. | a new phosphonopeptide, alafosfalin, was evaluated for in vitro antibacterial activity and for synergism with beta-lactams, using 475 japanese clinical isolates from urinary tract infections. alafosfalin was found to be highly active against escherichia coli and moderately active against serratia, klebsiella, enterobacter, and citrobacter, but less active against gram-positive organisms than were beta-lactams such as cephazolin or ampicillin and inactive against indole-positive proteus, pseudomo ... | 1979 | 518073 |
| [changes in the bacterial flora of patients under antineoplastic treatment]. | the bacterial flora of the skin from different anatomical sites on cancer patients and a control group of medical personnel was examined. this was done to ascertain if antineoplastic therapy was able to change the pattern of microbial flora of patients and to provide a control for possible infectious complications. the results show that in the control group bacterial flora was normal and the antineoplastic treatment did not succeed in changing the bacterial pattern in the skin of patients deeply ... | 1979 | 518758 |
| determination of the absolute configuration of mono-saccharides in complex carbohydrates by capillary g.l.c. | the absolute configuration of neutral monosaccharides, 2-acetamido-2-deoxy sugars, and uronic acids can be determined by capillary g.l.c. on se-30 after glycosidation with (-)-2-butanol and protection of the remaining polar groups. the method is illustrated by application to mixtures of the constituent sugars of the capsular polysaccharide from klebsiella type 57, alpha 1-acid glycoprotein, mucus glycoproteins, and the methylated, acidic polysaccharide from the coccoliths of emiliania huxleyi (l ... | 1979 | 519653 |
| structure of the capsular polysaccharide of klebsiella k-type 63. | structural investigation of the capsular polysaccharide from klebsiella k type 63 by methylation analysis, periodate oxidation, and uronic acid degradation showed the repeating unit to consist of leads to 3)-alpha-d-galp-(1 to 3)-alpha-d-galpa-(1 to 3)-alpha-l-fucp(1 to. this structure is identical to that of escherichia coli serotype k-42 capsular polysaccharide. the 1h- and 13c-n.m.r. spectra of the original and modified polysaccharide are consistent with the foregoing structure. | 1979 | 519655 |
| susceptibility of aerobic and anaerobic gram-negative rods to cefoxitin and related compounds. | | 1979 | 521267 |
| causes of death in 31 newborn infants with myelomeningoceles. | eight of the ten premature infants died during the first ten days. six of these were in poor general condition with cyanosis, respiratory distress or aspiration of amniotic fluid. one child died after a fit before he was operated upon for his myelomeningocele. ventricular haemorrhages were found in two premature infants. seven of the premature infants died of an infection. in 23 infants the myelomeningocele was not covered by a membrane. approximately 75% of the infants, i.e. 15, died during the ... | 1979 | 523668 |
| ly127935, a new beta-lactam antibiotic, versus proteus, klebsiella, serratia, and pseudomonas. | one hundred eight clinical isolates of proteus, klebsiella, serratia, and pseudomonas spp. were tested in vitro against ly127935, cefamandole, cefoxitin, ticarcillin, carbenicillin, gentamicin, tobramycin, and amikacin by broth microdilution. the activities of ly127935 were greater than or equal to those of the other antimicrobial agents against proteus vulgaris, klebsiella pneumoniae, and serratia marcescens. inhibitions were greatest, however, for ticarcillin and carbenicillin versus proteus m ... | 1979 | 526006 |
| silver-resistant enterobacteriaceae from hospital patients. | the inclusion of agar medium containing 0.5 mm agno3 in the hospital laboratory replicating system for routine antibiotic-susceptibility determinations resulted in identification of species of enterobacteriaceae (escherichia coli, enterobacter cloacae, klebsiella pneumoniae, proteus mirabilis, and citrobacter freundii) with silver resistance. since the study began in october, 1975, 11 in-hospital patients receiving silver sulfadiazine for burn wound prophylaxis have yielded silver-resistant bact ... | 1979 | 526888 |
| structure of klebsiella type 61 capsular polysaccharide. | an aldotriouronic acid was isolated from the acid hydrolyzate of the polysaccharide from klebsiella type 61 (k-61), and its structure was established. degradation of the permethylated polysaccharide with base established the identity of the sugar unit preceding the glucosyluronic acid residue. the modes of linkage and the sequence of different sugar residues were further confirmed by smith degradation of k-61. the anomeric configurations of the different sugar residues were determined by oxidati ... | 1979 | 526955 |
| structural studies of the capsular polysaccharide of klebsiella type 30. | | 1979 | 526959 |
| capsular polysaccharide of klebsiella type 30: x-ray diffraction results and idealised chain conformation. | | 1979 | 526960 |
| [antimicrobial activity of derivatives of 1,2,4-benzothiadiazine-1,1-dioxide. viii]. | the antimicrobial activity of a series of fluoro derivatives of benzothiadiazine and sulfonamides was studied. the compounds tested can be grouped as: a) 3-alkylmercapto derivatives of 6-trifluoromethyl-1,2,4-benzothiadiazine-1,1-dioxide (iii leads to vi); the 3-mercapto precursor (vii) and the related 3-picolinic salt (viii); b) 3-trifluoromethyl derivatives of 1,2,4-benzothiadiazine-1,1-dioxide and of its benzene substituted derivatives (ix leads to xvi); c) trifluoroacetylaminobenzenesulfonam ... | 1979 | 527707 |
| comparative in vitro activity of ly 127935 (6059-s), seven cephalosporins, three aminoglycosides, carbenicillin, and ticarcillin. | ly 127935 (6059-s), a new semi-synthetic beta-lactam antibiotic was tested simultaneously with 6 cephalosporins, 3 aminoglycosides, carbenicillin and ticarcillin against 398 clinical isolates of gram-negative bacilli and gram-positive cocci. many of the organisms were selected for study because of known resistance to one or more of the clinically available antibiotics tested. escherichia coli, klebsiella, serratia and providencia were susceptible to ly 127935. some resistant strains of enterobac ... | 1979 | 528361 |
| effect of disinfectants with and without usage of detergent for the flexible fiberoptic bronchoscope. | the purpose of this study was to find a safer, more rapid and easier disinfection process for the flexible fiberoptic bronchoscope (f.f.b.) by using ordinary disinfectants and a detergent. klebsiella pneumoniae, pseudomonas aeruginosa, staphylococcus aures, e. coli, serratia marcescens and candida albicans were used as sources of contamination. the mixed bacterial growth preparations for contamination of the f.f.b. were the same as those previously mentioned in our study. comparative bacteriolog ... | 1979 | 529489 |
| bactericidal effect of combinations of antimicrobial drugs and antineoplastic antibiotics against gram-negative bacilli. | six antineoplastic antibiotics showed little antibacterial activity against 28 strains of four species of gram-negative enteric bacteria. by using the cellophane transfer technique, combinations of these agents with 16 antibacterial drugs usually showed indifference. however, combinations of mitomycin c, especially with the aminoglycosides, were synergistic on strains of escherichia coli, proteus, and klebsiella pneumoniae. bleomycin, on the other hand, often showed antagonism on strains of e. c ... | 1979 | 533257 |
| antibacterial activities, nephrotoxicity, and ototoxicity of a new aminoglycoside, win 42122-2. | win 42122-2 is a new aminoglycoside antibiotic obtained from a mutant strain of micromonospora purpurea. in vitro and in vivo comparisons of win 42122-2 with gentamicin and amikacin revealed that win 42122-2 generally was less active than gentamicin against pseudomonas and many enterobacteriacae, especially klebsiella and indole-negative proteus. against most gentamicin-susceptible isolates, win 42122-2 was more active than amikacin. gentamicin-resistant clinical isolates were usually resistant ... | 1979 | 533261 |
| in vitro activity of ly127935, a new 1-oxa cephalosporin, against aerobic gram-negative bacilli. | a total of 434 clinical aerobic gram-negative bacillary isolates were tested against ly127935, a new 1-oxa cephalosporin, and compared with other cephalosporins, penicillins, and aminoglycosides by a broth microdilution technique. cefotaxime (hr756), a new semisynthetic cephalosporin, and ly127935 were more active, and showed lower minimum inhibitory concentrations (ranges, less than or equal to 0.12 to 2.0 micrograms/ml), than cefamandole, cefoxitin, and cefazolin against escherichia coli, kleb ... | 1979 | 533267 |
| reticular dysgenesis: report of two brothers. | we describe two brothers with marked leucopenia, lymphopenia, no immunologicl response to infections (no ig production, negative pha response and very low number of t and b lymphocytes in peripheral blood) and hypocellular marrow. they died at 12 and 8 days of life with infection (e. coli and klebsiella, respectively). | 1979 | 535190 |
| [spontaneous pure subcapsular renal hematoma. 2 cases (author's transl)]. | the first patient was a 33-year-old woman, diabetic, hypertensive, in whom the haematoma was due to rupture of a klebsiella abcess of the kidney. the second patient was a 68-year-old woman, who for several months had suffered from renal lithiasis complicated by urinary infections. spontaneous sub-capsular haematoma of the kidney is rare (21 cases published since 1960, including 2 personal). the diagnosis must be considered in the presence of a characteristic double-contour seen on a plain x-ray ... | 1979 | 537874 |
| [klebsiella enterobacter septicemia in newborn infants]. | | 1979 | 538278 |
| gas chromatographic analysis of in situ cyclitol utilization by klebsielleae growing in redwood extracts. | gas chromatographic analysis was employed to demonstrate in situ cyclitol utilization in aqueous extracts of redwood by isolates of klebsiella, enterobacter, and several other genera of gram-negative bacteria. in aqueous redwood extracts, all but one of the klebsiella and enterobacter isolates tested reached densities exceeding 5.0 x 10(6) cells/ml within 4 days, and all utilized pinitol and sequoyitol. other enteric bacteria did not utilize cyclitols in this extract. a defined minimal medium, c ... | 1979 | 539819 |
| synthesis of a selective agar medium for yersinia enterocolitica. | a new agar medium for isolation of yersinia enterocolitica was formulated based on growth studies which defined an optimum basal, and the evaluation of selective chemical agents, dyes, and antibiotics. the final formulation, designated cefsulodin-irgasan-novobiocin(cin) agar, provided quantitative recovery of 40 different strains of y. enterocolitica in 24 h using incubation at 32 degrees c or with 48 h of incubation at 22 degrees c. the medium was highly selective, especially against pseudomona ... | 1979 | 540256 |
| bactericidal activity of cefadroxil, cephalexin, and cephradine in an in vitro pharmacokinetic model. | cefadroxil (duricef, mead johnson and company), resembles cephalexin and cephradine in spectrum of antibacterial activity but differs in human pharmacokinetic properties. whether the latter are likely to affect activity in vivo was assessed by determining bactericidal activity against clinical isolates under conditions simulating the variation of drug concentration in the blood stream after an oral dose of 500 mg to adults. in this kinetic model, cefadroxil was more active than cephalexin or cep ... | 1979 | 541265 |
| [occurrence of pyruvic acid in capsular polysaccharides (k antigens) of klebsiellas]. | the capsular polysaccharides of 77 klebsiella k-types were analysed for the presence of pyruvic acid. one half of the polysaccharides investigated were found to contain between 1.3 and 12% of the keto acid. a comparison between the analyses performed and the calculated values from some pyruvic acid containing polysaccharides of known structure showed that there is only in 5 out of 10 cases a good correlation with a regular substitution of the oligosaccharide repeating units. | 1979 | 543156 |
| medium for the presumptive identification of aeromonas hydrophila and enterobacteriaceae. | a medium was devised for the rapid presumptive identification of aeromonas hydrophila. it also offered good differentiation of klebsiella, proteus, and other enteric species. mannitol fermentation, inositol fermentation, ornithine decarboxylation and deamination, indole production, motility, and h2s production from sodium thiosulfate and cysteine could be recorded in a single tube of the medium. | 1979 | 543697 |
| synergistic action between sisomicin and mezlocillin against gram-negative bacteria and staphylococcus aureus. | the combined effect of sisomicin and 6-[(r)-2-[3-methylsulfonyl-2-oxo-imidazolidine-1-carboxamido]-2-phenyl-acetamido-a1-penicillanic acid sodium salt (mezlocillin, baypen) was studied against 50 bacterial strains, including pseudomonas aeruginosa, proteus spp. klebsiella-enterobacter, e. coli and staphylococcus aureus. no antagonism or indifference was detected with the strains studied. both antibiotics were synergistic against 62% of the strains, and partially synergistic against 38%. out of t ... | 1979 | 543894 |
| treatment with azlocillin in complicated urinary tract infections. | 20 patients, aged 18-84 years, with complicated urinary tract infections admitted to hospital were treated with 6-[(r)-2-(2-oxo-imidazolidine-1-carboxamido)-2-phenyl-acetamido]-penicillanic acid sodium salt (azlocillin, securopen) for 5 to 10 days. isolated bacteria were pseudomonas aeruginosa (14), proteus mirabilis (3), escherichia coli (2) and klebsiella spp. (1). serum concentrations and urine recovery were measured on the fifth day of treatment. the mean serum half-life was 1.85 h and the m ... | 1979 | 543906 |
| [experience with the combination mezlocillin/oxacillin in severe bacterial infections in a children's surgical ward (author's transl)]. | severe bacterial infections accompanying conditions during childhood which demand for surgical intervention mostly are caused by staph. aureus, e. coli, klebsiella/aerobacter or ps. aeruginosa. 20 patients, 10 of them suffering from a putrid peritonitis, showed a good efficacy of optocillin (bay 1-1330), a combination of 6-((r)-2-[3-methylsulfonyl-2-oxo-imidazolidine-1-carboxamido]-2-phenyl-acetamido)-penicillanic acid sodium salt (mezlocillin, baypen) and 5-methyl-3-phenyl-4-isoxazolylpenicilli ... | 1979 | 543915 |
| biochemical properties and drug sensitivity of klebsiella species isolated in lusaka. | | 1979 | 544262 |
| morphologic homogeneity of bacteriophage and their lytic activity. | | 1979 | 546103 |
| comparative study on biological markers efficiency with epidemiological applications in human infections produced by klebsiella. | | 1979 | 546371 |
| [antibacterial kinetics of fosfomycin (author's transl)]. | the authors studied, with the autobac machine, the kinetics of antibacterial activity of fosfomycin against staphylococcus aureus, streptococcus d' streptococcus pneumoniae, neisseria meningitidis, acinetobactor lwoffi, haemophilus influenzae, salmonella typhimurium, escherichia coli, proteus rettgeri, klebsiella pneumoniae, serratia marcescens and pseudomonas aeruginosa. a correlation appears between the kinetics of fosformycin antibacterial action and the microbial growth rate. | 1979 | 547759 |
| [antimicrobial effect of derivatives of 1,2,4-benzothiadiazin-1,1-dioxide. vii]. | series of alkyl derivatives of the following have been prepared: 5,7-dichloro- [compounds (ii leads to v)], 6-methyl- [compounds (vi leads to ix)] and 6-methoxy-3-mercapto-1,2,4-benzothiadiazine-1,1-dioxide [compounds (x leads to xiii)]. the products were tested for antimicrobial activity. studies were also made of the corresponding 3-mercapto precursors (xiv, xv, xvi) and the relative 3-picolinium salts (xvii, xviii, xix) and also of the 3-picolinium salts of 6-chloro-, 7-chloro- and 6,7-dichlo ... | 1979 | 553823 |
| studies on the inhibitory effects of zinc heptanoate on microorganisms. | inhibitory effect of zinc heptanoate was observed on different cultures of bacteria and fungi. growth of all the bacteria was inhibited by the compound. greatest inhibition was seen in the case of staphylococcus albus, streptococcus pyogenes, shigella dysenteriae, shigella sonnei, shigella flexneri, salmonella typhi, s. paratyphi a, s. paratyphi b, vibrio cholerae, corynebacterium diphtheriae, and e. coli whereas least inhibition was found in the case of staphylococcus aureus. in triethanolamine ... | 1979 | 553835 |
| [bacteriology of urinary infections in paraplegics (author's transl)]. | the aa. report the results of 300 urine cultures carried out on paraplegics hospitalized in the centro paraplegici of ostia since 1970 to the end of 1977. all the patients were catheterized. they found infections in the 73 to 92% of the examined cases in the different years. the most frequently isolated bacterial species in the years 1970, 1971, and 1972 were escherichia, staphylococcus and enterococcus, whereas were proteus, citrobacter, klebsiella and psuedomonas in the following years. they b ... | 1979 | 554546 |
| [annual usage in a general hospital of antimicrobials and frequency of resistant bacterial strains (author's transl)]. | the data concerning annual usage in a general hospital and the frequency of resistant bacterial strains, isolated from patients with urinary tract's infection from 1975 to 1977 were collected and statistically processed. it was noticed that the year by year variation of resistance were mainly confined to e. coli and p. mirabilis. increasing resistance with time was found for e. coli with co-trimoxazole, p. mirabilis with cephaloridin and gentamicin, proteus indole-positive with rifampicin. reduc ... | 1979 | 555536 |
| [the role of enteric bacteria in childhood urinary tract infections and their in vitro response to antimicrobial agents]. | in this study, 154 cases of suspected bacterial urinary tract infection were examined bacteriologically. urine cultures yielded, e. coli in 84 patients citrobacter in 22 (c. freundii: 9, c. diversus: 9) proteus in 21 (p. vulgaris: 6, p. morgani: 4, p. rettgeri: 2. p. mirabilis: 4, lactose fermenting strains: 5), pseudomonas in 12 (p. aeruginosa: 5, other strains of pseudomonas: 7), klebsiella in 9 (k. aerogenes: 3, k. pneumonia: 6) and enterobacter in 6 patients (e. aerogenes: 1, e. cloacae: 5). ... | 1979 | 555789 |
| [severe infections in our obstetric-gynecologic case material including nosocomial infections (1972--1976) (author's transl)]. | a consideral by increased incidence of severe infections in 1975 provided the impetus for a critical analysis of such cases (n = 29) during the last four years. in the group of infections acquired outside the hospital setting, 13 were adnexal infections and 2 were amniotic infections. the group of true hospital infections (n = 14) consisted of 4 entoplastic cases, 7 cases with contaminated infusions and 3 cases of amniotic infections. a shift in the pathogenic spectrum in favor of gram-negative ... | 1977 | 558128 |
| humoral response in blood group p phenotype persons subjected to an avian environment. | the avian environment contains among many antigens, the blood group substance p1-p1 antigen is present in certain enterobacteriaceae found in bird droppings. examples include enterobacter, klebsiella, e. coli, enterobacter haffniae and proteus. p2 persons exposed to the avian environment may develop anti-p1 activity. a greater percentage of precipitins to bird antigens was found in p2 than in p1 persons. in p1 persons seven out of twenty-eight (25%) had precipitins to bird droppings. in p2 perso ... | 1977 | 560935 |
| [studies on the mastitis-metritis-agalactia syndrome (milk fever) in sows. iii. galactogenic induction of klebsiella-induced mastitis]. | | 1977 | 561440 |
| pullulanase, an enzyme of starch catabolism, is associated with the outer membrane of klebsiella. | | 1978 | 565627 |
| ["hepatoportal pneumatosis with pneumatosis intestinalis in the neonate" (author's transl)]. | a fullterm newborn infant two weeks of age, suffering from congestive heart failure due to a large patent ductus arteriosus, deteriorated suddenly presenting with a paralytic ileus. radiographically diffuse intestinal pneumatosis and gas in the portal vein system could be shown. a mechanical reason was excluded by laparotomy shortly after which the infang died. out of blood klebsiella pneumonia could be grown. a survey of the literature on the syndrome of pneumatosis intestinalis and gas emboliz ... | 1978 | 566818 |
| electron microscopic study of previously irradiated scleroma. | nasal biopsies from 2 scleroma patients who had received previous x-ray therapy were investigated under the electron microscope. in the lamina propria, the majority of mikulicz cells contained numerous small vacuoles. this was attributed to the effect of x-ray therapy causing temporary suppression of the inflammatory process followed by new granuloma formation. the vacuoles of the mikulicz cells contained some fine granular and fibrillar material of unknown origin. rounded electron-dense bodies ... | 1979 | 572955 |
| sulfamethoxazole-trimethoprim for infections in cancer patients. | a combination of sulfamethoxazole and trimethoprim (bactrim) was given orally to 35 cancer pattients with infections. thirty-two patients did not respond to an initial antibiotic regimen that consisted primarily of carbenicillin disodium and an aminoglycoside. there were 18 single-organism, gram-negative infections. the overall cure rate was 54%. the most common infection was pneumonia (47% responded to treatment). eighty precent of the cases of septicemia were cured. the most common infecting o ... | 1977 | 576166 |
| amikacin therapy for serious gram-negative infection. | amikacin sulfate was administered to 18 patients for the treatment of 19 severe infections. seventeen infections were caused by gentamicin-resistant gram-negative bacilli, and 13 patients were bacteremic. bacteriologic cure was attained in all but one instance, and effective serum, bile, and pleural fluid drug levels were demonstrated. drug-related fever occurred in one patient, and another experienced a maculopapular rash and monilial intertrigo. in three patients, reversible renal toxicity dev ... | 1977 | 576282 |
| mycotic cervical carotid aneurysm. | a case of ruptured mycotic aneurysm involving the extracranial carotid artery is presented. klebsiella was found to be the responsible pathogen. carotid artery mycotic aneurysms are discussed with emphysis on the dilemma of surgical treatment. after aneurysm resection the carotid flow either must be re-established or the carotid vessels ligated. a review of the literature reveals that the majority of grafts or arterial repairs fail if reconstruction is carried out in an infected field. the conse ... | 1977 | 576507 |
| absorption and excretion of carbenicillin indanyl sodium in patients with reduced kidney function. | on eight volunteers with reduced kidney function, 1 g of carbenicillin indanyl sodium was administered orally for the single dose studies and was given orally in a dose of 1 g every 6 h for 7 days for the multiple dose studies. the patients were divided into two groups according to their kidney functions: group i moderately impaired and group ii severely impaired. in the single dose studies, the mean peak level was 12.6 microgram/ml for group i and 26.9 microgram/ml for group ii. in the multiple ... | 1977 | 578496 |
| persistent meningeal inflammation associated with intrathecal gentamicin. | a 30-year-old woman was treated with intraventricular gentamicin for klebsiella meningitis. cultures became sterile, but meningeal inflammation, associated with high central spinal fluid gentamicin levels, persisted until gentamicin was discontinued. | 1977 | 579718 |
| [intrathecal gentamicin in the treatment of meningitis--clinical case study (author's transl)]. | the authors report 33 cases of meningitis treated with intrathecally administered gentamicin (gm) and examine it's effectiveness for meningitis side effects and optimum dose. of 33 cases 15 cases (group i1 were treated with gm alone 7 cases (group iia) with gm combined with sb--pc or cp. in 8 cases of the other 11 cases (group iib) gm was changed for sb--pc or cp because of it's inefficiency and side effects (6 cases) and other reasons (2 cases). in the remaining three cases of group iib sb--pc ... | 1978 | 581556 |
| [bacteriological and clinical evaluation of a dicloxacillin-ampicillin combination (author's transl)]. | this paper presents the results of the bacteriological and clinical assessment of the dicloxacillin-ampicillin combination totocillin. the bacteriological examinations show that a synergistic and hyperadditive effect particularly on staphylococcus, but also on e. coli, klebsiella-enterobacter and in a few cases on proteus spp. is achieved with the combination. clinical experience in urinary tract infections evidences the good efficacy of the combined preparation, which on statistical evaluation ... | 1978 | 581996 |
| [dibekacin--a novel aminoglycoside antibioticl. antimicrobial activity and parallel resistance in vitro]. | dibekacin (orbicin) is a new aminoglycoside antibiotic which chemically differs from tobramycin only by lack of an oh-group. the activity of dibekacin against e. coli, klebsiella, enterobacter, serratia, proteus indol-negative and indol-positive and pseudomonas aeruginosa was compared with that of gentamicin, sisomicin, tobramycin and amikacin by tube dilution procedure. dibekacin showed a high activity against p. aeruginosa including gentamicin-resistant strains. the development of resistance a ... | 1979 | 582126 |
| comparison of cefazedone with cefazolin and cephalothin in treatment of experimental infections in mice. | the chemotherapeutic efficacy of (6r,7r)-7-(2-[3,5-dichloro-4-oxo-1(4h)-pyridyl]-acetamido)-3-([(5-methyl-1,3,4-thiadiazol-2-yl)-thio)-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid (cefazedone, refosporen) was assayed in comparison to cefazolin and cephalothin in experimental bacterial murine infections with 6 gram-positive and 8 gram-negative strains of the genera staphylococcus, streptococcus, pneumococcus, escherichia, klebsiella, proteus, pasteurella and salmonella. in 5 out of ... | 1979 | 582716 |
| laboratory studies on mecillinam: activity alone and combined with cephradine. | mecillinam (mc) was found to be inhibitory at low concentrations to a wide range of gram-negative bacteria; the sensitivity of such strains could be predicted by using a 10 microgram disk. resistance to mc did not appear to be associated with beta-lactamase-mediated destruction of the antibiotic. ampicillin-resistant strains tended to be less sensitive to mc. mc and cephradine acted synergistically against proteus mirabilis, pr. vulgaris, prov. stuartii and serratia marcescens, and the combinati ... | 1977 | 587708 |
| hands as route of transmission for klebsiella species. | seventeen per cent of the staff of an intensive care ward were found to have klebsiella spp contaminating their hands, and these strains could be related to serotypes infecting or colonising patients in the ward on the same day. we identified some simple ward procedures that resulted in contamination of nurses' hands with 100-1000 klebsiellae per hand. klebsiellae survived on artifically inoculated hands for up to 150 minutes. handwashing with chlorhexidine hand cleanser reliably gave 98-100% re ... | 1977 | 589166 |
| klebsiella serotype-13 capsular polysaccharide: primary structure and depolymerization by a bacteriophage-borne glycanase. | periodate oxidation and smith degradation, methylation analysis including uronic acid degradation, partial hydrolysis with acid, bacteriophage degradation, and p.m.r. spectroscopy have been used to elucidate the primary structure of the klebsiella serotype-13 capsular polysaccharide. the polymer consists of pentasaccharide repeating-units comprising a 4)-beta-d-manp-(1 leads to 4)-alpha-d-glcp-(1 leads to 3)-beta-d-glcp-(1 leads to chain with a 3,4-o-(1-carboxyethylidene)-beta-d-galp-(1 leads to ... | 1977 | 589608 |
| structural investigation of klebsiella serotype k62 polysaccharide. | | 1977 | 589609 |
| [cystoid pneumonia, apropos of a case]. | | 1977 | 589744 |
| [clinical experience with s-6436 in acute pyelonephritis (author's transl)]. | s-6436 (a preparation consisting of 30% of non-enteric coated granules and 70% of enteric coated ones) was orally administered to the patients with acute pyelonephritis, and the following results were obtained: 1. subjective symptoms: very good in 13 cases (65%), good in 1, fair in 2 and poor in 4. 2. urine finding: very good in 13 cases (65%), good in 3 and poor in 4. 3. disappearance of causative organisms: organisms which were identified in the first examination were 17 strains of e. coli, on ... | 1977 | 592482 |
| [clinical efficacy of s-6436 in urinary tract infection (author's transl)]. | s-6436 was orally given to the patients mainly with uncomplicated acute cystitis at two divided doses for 7 days with the following results: 1) one or 2g/day of s-6436 were administered to the patients with 93.7% of effectiveness. there is almost no difference in effectiveness between 1 g and 2g dosages. 2) bacteria in urine disappeared in 74% of the patients treated and superinfection occurred in 22%. the disappearance of the bacteria was observed in 83.3% of the patients with e. coli and 60% w ... | 1977 | 592484 |
| [the epidemiology of blastomyces infections with special reference to postoperative intensive care wards (author's transl)]. | 230 strains of blastomyces were isolated during a nine month's period in the course of routine laboratory examinations of faecal and other specimens. candida albicans was the most frequently present (151), followed by candida tropicalis (39) and torulopsis glabrata (16). during an environmental study in a postoperative intensive care unit 426 swabs were taken. 88 strains of blastomyces were cultured from 75 swabs. the observations indicate that candida albicans as a free-living organism lacks fa ... | 1977 | 594031 |