| immunocytochemical detection of helicobacter pylori in formalin fixed tissue biopsy specimens. | | 1990 | 2199535 |
| survival of helicobacter pylori in water and saline. | | 1990 | 2199542 |
| identification of campylobacter pylori by gastric brush cytology. | | 1990 | 2201508 |
| helicobacter pylori: bridging the credibility gap. | in summary, therefore, there are interesting associations between h pylori, duodenal ulcer, and non-ulcer dyspepsia. in type b gastritis there may be enough evidence to suggest a causal role. the relation between gastritis and upper gastrointestinal symptomatology, however, remains contentious. the relation between h pylori and acid secretion may be more intimate than was previously thought. 'pylorites' must temper their enthusiasm and provide hard data; 'schwartzians' must broaden their horizon ... | 1990 | 2201586 |
| helicobacter (= campylobacter) pylori in africa. | epigastric pain is a common complaint throughout africa, mostly in the form of non-ulcer dyspepsia. it has recently been suggested that helicobacter (= campylobacter) pylori, a bacterium that colonizes the gastric mucosa and causes type b gastritis, may be the cause of this epigastric pain. this paper reports the endoscopic, histological and bacteriological findings in 57 patients presenting with epigastric pain to the university of maiduguri teaching hospital during one year, together with a re ... | 1990 | 2202107 |
| effects of sucralfate and sulglycotide treatment on active gastritis and helicobacter pylori colonization of the gastric mucosa in non-ulcer dyspepsia patients. | we conducted a double-blind randomized treatment study on patients affects by non-ulcer dyspepsia in whom multiple biopsy specimens showed active gastritis. patients were given either 3 g/day of sucralfate (n = 39) or 600 mg/day of sulglycotide (n = 50) for 6 wk, a glycopeptide isolated from pig duodenum constituents. endoscopy was carried out at baseline and at the end of treatment. we took biopsies from the gastric body (twice) and antrum (six times) at each endoscopy in order to determine gra ... | 1990 | 2202200 |
| [efficacy of a bismuth combination preparation. efficacy in the treatment of chronic active gastritis and non-ulcerous dyspepsia]. | in an open, randomized controlled study, the effect of a combined bismuth preparation, bismuth nitrate and bismuth aluminate on the elimination of helicobacter pylori, inflammatory activity in the gastric mucosa in chronic type b gastritis, and on the patient's symptoms was investigated. included in the study were 36 patients with non-ulcerous dyspepsia and chronic gastritis. twelve patients (group a) received 4 x 1 tablet a day (800 mg total daily dose), 12 patients (group b) 2 x 2 tablets a da ... | 1990 | 2202619 |
| campylobacter pylori in israel: prospective study of prevalence and epidemiology. | antral biopsy samples were taken from 147 patients undergoing gastroscopy. campylobacter pylori was cultivated from 100 of these patients. c. pylori was isolated from 76% of the specimens showing any degree of histologic gastritis, but from only 11% of specimens with completely normal histology. a questionnaire was completed on all patients and included demographic, epidemiologic and clinical information. sephardic origin, smoking, and a bad taste in the mouth were more prevalent in the campylob ... | 1990 | 2205596 |
| the radiologic and endoscopic investigation and etiologic classification of gastritis in children. | in 11 children the endoscopic criteria for gastritis were correlated with radiologic and pathological findings. an etiologic classification is proposed. the diagnoses included gastric involvement by crohn's disease (five children), eosinophilic gastroenteritis (one), diffuse varioliform gastritis (two), erosive gastritis associated with campylobacter pylori infection (two) and idiopathic erosive gastritis (one). eight of the nine double-contrast barium studies and only one of the three single-co ... | 1990 | 2207775 |
| gastrointestinal function and structure in hiv-positive patients. | we examined 19 patients (17 men) with human immunodeficiency virus (hiv) infection and gastrointestinal symptoms to determine whether those symptoms were due to either a gastrointestinal tract infection or a defect in mucosal absorption because of an enteropathy. the erythrocyte folate and serum vitamin b12 levels were within normal limits in all of the patients. the serum ferritin level was elevated in 12. the xylose absorption test results were abnormal in 8 of the 13 patients able to complete ... | 1990 | 2207920 |
| identification of campylobacter pylori by endoscopic brush cytology. | to investigate the value of papanicolaou-stained endoscopic brush samples in the diagnosis of campylobacter pylori infection of the upper gastrointestinal tract, 138 brush and biopsy samples from the esophagus, stomach, and duodenum, taken concomitantly, were reviewed retrospectively. in 35 cases, campylobacter-like organisms (clos) were found in both cytology and biopsy samples. in 15 cases, clos were seen in biopsy material only, and in 8 cases, clos were found in cytology material only. clos ... | 1990 | 2209347 |
| development of a human stomach explant organ culture system to study the pathogenesis of helicobacter pylori. | these studies were undertaken to define conditions under which helicobacter (formerly campylobacter) pylori and viable human gastric mucosa could coexist in tissue culture with the ultimate goal of developing an in vitro experimental model which could be used to study interactions between h. pylori and gastric epithelium. antral gastric biopsies obtained at upper endoscopy were placed in culture in either cmrl-1066 or keratinocyte growth media and incubated at 37 degrees c in either an oxygen-en ... | 1990 | 2210096 |
| a small animal model of human helicobacter pylori active chronic gastritis. | isolation of a spiral-shaped bacterium closely related to helicobacter pylori from the cat stomach made it possible to investigate new small animal models of gastric infection. pure cultures of this bacterium, provisionally named "helicobacter felis," were fed to germ-free mice. the organism colonized the stomach in large numbers in mucus and deep in the gastric pits and showed the same gastric trophism found with h. pylori. significant histopathology was seen in all h. felis-infected mice. at 2 ... | 1990 | 2210240 |
| reduction of gastric ulcer recurrence after suppression of helicobacter pylori by cefixime. | the effect on the recurrence of gastric ulcers after suppression of helicobacter pylori by combined treatment with cimetidine and the antimicrobial drug cefixime was investigated. twenty one of 43 patients with endoscopically proved gastric ulcer and h pylori infection were randomly assigned to receive cimetidine 800 mg daily for 12 weeks; the remaining 22 patients received cimetidine 800 mg daily for 12 weeks plus cefixime 100 mg daily for the last two weeks. after treatment, 88% of 17 patients ... | 1990 | 2210464 |
| adjuvant antibiotic therapy in duodenal ulcers treated with colloidal bismuth subcitrate. | persistence of helicobacter pylori after duodenal ulcer healing is associated with high rates of ulcer relapse. we compared colloidal bismuth subcitrate alone with cbs combined with one of four antibiotic regimens in the treatment of duodenal ulcers. endoscopy and antral biopsies were performed before treatment and four weeks afterwards. biopsy specimens were examined for histological evidence of gastritis and by gram stain and culture for h pylori infection. altogether 141 patients were allocat ... | 1990 | 2210469 |
| geographic association of helicobacter pylori antibody prevalence and gastric cancer mortality in rural china. | to examine the geographic association between helicobacter pylori infection and gastric cancer, we have assessed the prevalence of igg antibodies to h. pylori in plasma samples taken in 1983 from 1882 men, aged 35-64 years, in 46 rural counties of the people's republic of china. the gastric cancer mortality rates in these countries in 1973-75 varied from 3 per 1,000 (cumulative rate, 0-64 years) to 69 per 1,000, while the proportions of the population positive for h. pylori antibodies (based on ... | 1990 | 2210881 |
| serum pepsinogen i and gastrin concentrations in children positive for helicobacter pylori. | serum pepsinogen i, serum gastrin concentration, and inflammatory scores were measured in a population of 71 children undergoing upper gastrointestinal endoscopy for investigation of upper abdominal pain. forty four were initially colonised with helicobacter pylori. the indices were measured before treatment (in 71 children), one month (in 41 children), and six months (in 21 children) after stopping treatment. before treatment there was a significant correlation between serum pepsinogen concentr ... | 1990 | 2212069 |
| the susceptibility of campylobacter pylori to antiulcer agents and antibiotics. | the antibacterial activities of antiulcer agents and antibiotics against campylobacter pylori were studied. the mic90 values of three kinds of antibiotics--macrolides, beta-lactams, and metronidazole--were 0.05-0.78, 0.39-1.56, and 12.5 micrograms/ml, respectively. they were more active than antiulcer agents such as h2-blockers and cetraxate with mic90 values of greater than or equal to 1,600 and greater than 1,600 micrograms/ml, respectively. especially, clarithromycin, a new derivative of eryt ... | 1990 | 2212539 |
| evidence for gastric mucosal cell invasion by c. pylori: an ultrastructural study. | it is now generally accepted that campylobacter pylori is closely associated with peptic ulcer disease and chronic type b gastritis. whether c. pylori is the direct etiologic cause of either or both of these illnesses remains unclear. possible pathophysiologic effects of c. pylori are still a matter of debate and conjecture. utilizing a small group of patients with gastric ulcers and chronic gastritis, we examined the ultrastructural relationship between c. pylori and gastric cells. forty-eight ... | 1990 | 2212556 |
| campylobacter pylori interactions with gastric cell tissue culture. | many investigators have reported that gastric mucosal biopsies of patients with chronic gastritis and peptic ulcer disease show the presence of campylobacter pylori in a large majority of cases. histologic examinations of such tissues indicate a close approximation of c. pylori with gastric surface epithelial cells. a recent report has described both adherence and cell invasion of gastric cells by c. pylori. using a transmission electron microscope, we have examined the interaction between c. py ... | 1990 | 2212557 |
| [comparison of three methods for detecting campylobacter pylori and measurement of human antibody titers against the whole organisms]. | in order to detect campylobacter pylori in the gastric mucosa, three different methods as 1) culture of the organisms, 2) immunostaining by monoclonal antibody against the cells, and 3) urease test were compared. in the disease group, positive % of each methods was 64, 75 and 74. however, positive % common to the three methods was only 48. the corresponding rate of culture and urease tests, and that of culture and staining methods was 81% and 60%, respectively. therefore, it was concluded that u ... | 1990 | 2212754 |
| [examination of distribution of helicobacter pylori on gastric mucosa using dye endoscopy]. | | 1990 | 2214287 |
| preliminary study on the microbiology of campylobacter pyloridis and gastric histopathology. | biopsy samples were taken endoscopically from the antral-mucosa of 693 patients with peptic ulcer and chronic gastritis presenting dyspepsia symptoms. campylobacter pyloridis cultures were positive in 59 of 98 (60.2%) cases and histopathologically the organisms were found in 411 of 693 cases (59.3%). pathologically, campylobacter pyloridis was positive in 273 out of 300 patients with chronic superficial gastritis (91.0%), in 102 of 249 patients with chronic atrophic gastritis (40.9%), in 36 out ... | 1990 | 2214500 |
| [campylobacter pylori in patients with peptic ulcer and chronic gastritis: immunologic response]. | | 1990 | 2214616 |
| [campylobacter pylori and its role in the pathogenesis of selected diseases of the stomach and duodenum]. | | 1990 | 2216966 |
| clinical recognition and evaluation of peptic ulcer disease. | when a patient has epigastric pain that worsens 1 to 3 hours after meals, the possibility of peptic ulcer disease should be considered. completely typical clinical presentations in patients younger than age 50 justify empirical therapy when no physical or laboratory findings suggest a mimicking disorder. esophagogastroduodenoscopy should be undertaken when response to therapy is incomplete, symptoms recur quickly, or dyspeptic symptoms present for the first time in a patient older than age 50. w ... | 1990 | 2216988 |
| [chronic gastritis. pathogenesis, clinical aspects and therapy]. | based on clinical and histopathological features, three different types of chronic gastritis can be distinguished: gastritis a is confined to the proximal stomach and is the result of an autoimmunological process with antibodies against parietal cells and intrinsic factor. it is a rare disorder and may lead to pernicious anaemia. distal, antral gastritis b is caused by an infection of the gastric mucosa with helicobacter pylori (hp). its incidence increases with age (greater than 50% above age 5 ... | 1990 | 2218459 |
| [the histological diagnosis of chronic gastritis. a german proposal for an integrated nomenclature]. | the gastrointestinal pathology study group of the german pathological society has drawn up a proposal for a unifying nomenclature for the graduation and classification of gastritis. the severity of chronic gastritis is divided into 4 grades (minimal, light, moderate and severe) and the activity of the process is characterized by 3 grades (grade 1, 2 and 3 activity). in addition, the presence or absence of helicobacter pylori (formerly campylobacter pylori), the extent and type of intestinal meta ... | 1990 | 2218460 |
| [current perspectives in ulcer disease]. | 1. helicobacter pylori has been associated with chronic type-b gastritis, which in turn is always present in duodenal ulcer patients; therefore, it is likely that helicobacter pylori is an important cofactor in the pathogenesis of peptic ulcer disease. an eradication of helicobacter pylori is associated with the reduced ulcer relapse rate, but an effective therapy for eradication is not yet available and should be restricted to experimental protocols. 2. omeprazole is an antagonist of the proton ... | 1990 | 2218969 |
| [campylobacter pylori and treatment of duodenal ulcer]. | the authors subjected to endoscopic examination 90 patients with duodenal ulcers. from each patient they collected a bioptic specimen of the gastric antrum and duodenal bulbus for microbiological and histological examination. they found that for detection of c. pylori the microscopic examination was most useful. the presence of c. pylori in the gastric antrum was detected in 87% of the subjects and in the duodenal bulb only in 48%. the difference is significant at the 0.01 level. to 43 patients ... | 1990 | 2219764 |
| hyperplastic gastric polyps associated with persistent helicobacter pylori infection and active gastritis. | we report two cases of patients with 3-yr histories of upper gastrointestinal symptoms, hyperplastic gastric polyps, and active chronic gastritis. biopsies retrospectively stained with giemsa revealed the persistent presence of helicobacter pylori (hp) in gastric biopsies of both patients throughout the 3 yr. after treatment with amoxicillin and bismuth subsalicylate, both became asymptomatic, one demonstrating disappearance and recurrence of the gastric polyps in conjunction with the hp. these ... | 1990 | 2220735 |
| disaccharidases in duodenal biopsies in helicobacter pylori-positive patients. | | 1990 | 2220753 |
| association of helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy. | to determine the prevalence of helicobacter pylori in patients with non-ulcer dyspepsia and ulcer disease as well as in a control population undergoing endoscopic retrograde cholangiopancreatography (ercp) for suspected pancreatic or biliary disease. | 1990 | 2220879 |
| the prevalence of helicobacter pylori in nonulcer dyspepsia. importance of stratification according to age. | helicobacter pylori (formerly campylobacter pylori) is causally related to active antral gastritis and is highly associated with duodenal and gastric ulcers. however, the relationship of h pylori to nonulcer dyspepsia is less clear. we determined the presence of h pylori in unselected patients who were undergoing upper gastrointestinal tract endoscopy, and we found a prevalence of 37% in 110 patients with nonulcer dyspepsia that was similar to previous data. patients with nonulcer dyspepsia who ... | 1990 | 2222090 |
| [combination of glandular and foveolar hyperplasia of the gastric mucosa--a rare mixed type]. | in a 28 year-old man with epigastric pain endoscopy detected giant gastric folds and multiple superficial erosions. histologically a mixed form of glandular and foveolar hyper plasia of the gastric mucosa was suggested (ming's type iii). basal and pentagastrin stimulated secretion volume and acid output were moderately elevated, hypersecretion of protein was not found. serum levels of calcium and gastrin were normal, also after secretin stimulation. the mucosa of the corpus was extensively infes ... | 1990 | 2222791 |
| [advances in the research of pathogenicity of campylobacter pylori and epidemiology of its infection]. | | 1990 | 2225011 |
| in vitro susceptibility of helicobacter pylori to the new oral cephalosporins cefpodoxime, ceftibuten and cefixime. | the in vitro activity against 30 helicobacter pylori strains of three new third generation cephalosporins, cefpodoxime, ceftibuten and cefixime, which can be administered orally, was determined using an agar dilution technique under microaerophilic conditions. the mic50 and mic90 of cefpodoxime was 0.5 and 4.0 micrograms/ml respectively, of ceftibuten 2.0 and 8.0 micrograms/ml, and of cefixime 0.06 and 0.5 microgram/ml. all antibiotics showed good activity against helicobacter pylori, cefixime h ... | 1990 | 2226500 |
| natural history of congestive gastropathy in cirrhosis. the liver study group of v. cervello hospital. | in a prospective study of the natural history of congestive gastropathy, 212 consecutive cirrhotic patients (75 treated with sclerotherapy) were included. mean follow-up was 46 months. mild gastropathy (mosaiclike pattern) was found in 110 patients and severe gastropathy (granular mucosa with cherry spots) was found in 20. prevalence of helicobacter pylori, formerly campylobacter pylori, was 50% in patients without, 43% in those with mild, and 28% in those with severe gastropathy. congestive gas ... | 1990 | 2227271 |
| ranitidine in children with peptic ulcer and patients with pancreatic cystic fibrosis. | this article describes experience of the use of ranitidine in children with peptic ulcer and patients with pancreatic cystic fibrosis. ranitidine proved to be efficacious and well tolerated, the percentage of healing being 89.4%. ranitidine was also used in subjects with gastritis from campylobacter pylori, obtaining rapid regression of subjective symptoms. administration of ranitidine to cystic fibrosis patients improved the efficacy of the pancreatic extract, with consequent enhancement of dig ... | 1990 | 2228343 |
| gastrointestinal side-effects of octreotide during long-term treatment of acromegaly. | gastrointestinal side-effects of prolonged therapy (greater than 2 yr) with the long-acting somatostatin analog octreotide were studied in 10 acromegalic patients. after 2 yr of therapy, 6 of 10 patients had newly developed gallstones, complicated by cholangitis and jaundice in 1. serum vitamin b-12 concentrations declined in all 10 patients [from 380 +/- 32 to 172 +/- 21 pmol/l (mean +/- se); p = 0.023] and became abnormally low in 4. gastric biopsy specimens, obtained during gastroscopy (9 pat ... | 1990 | 2229321 |
| evaluation of two monkey species (macaca mulatta and macaca fascicularis) as possible models for human helicobacter pylori disease. | endoscopic, histologic, and microbiologic evaluations of 21 cynomolgus and 34 rhesus monkeys for naturally occurring helicobacter pylori infection were done. h. pylori was never isolated from any cynomolgus monkey, but was found in 12 rhesus monkeys. a general correlation existed between a positive culture and a gastric inflammatory response. inoculation challenges were then undertaken. four cynomolgus and five rhesus monkeys received two different h. pylori strains isolated from humans. five rh ... | 1990 | 2229353 |
| helicobacter pylori: has it a part in the lesion of the gastroesophageal reflux? | | 1990 | 2230279 |
| ultrastructure of a spiral micro-organism from pig gastric mucosa ("gastrospirillum suis"). | the ultrastructural features of a helical-shaped bacterium occurring in the stomach of pigs, within the mucus on the mucosal surface of antral pits, were examined. the bacterial cell had three to eight spiral turns, flattened and truncated ends and was approximately 4.0 microns long and 0.6 microns wide. in some sections, up to six flagella, about 22 nm in diameter, were seen arising from each pole. the cytoplasm contained sparse, irregular granules, numerous ribosomes and large single-layered m ... | 1990 | 2231673 |
| [detection of antibodies to helicobacter pylori with the immunoenzyme test and indirect immunofluorescence]. | sera from 56 adult patients were screened for the presence of igg antibodies against helicobacter pylori by enzyme immunoassay and indirect immunofluorescence. in addition, the detection of helicobacter pylori in antral biopsy specimens was attempted by culture and histological methods. colonisation of the antrum mucosa with helicobacter pylori was observed in 39 of the 56 patients. igg antibodies against helicobacter pylori were detected by enzyme immunoassay in 34 of 39 infected patients. thus ... | 1990 | 2233106 |
| a newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia. | we identified a motile, curved, gram-negative bacillus as the cause of persistent fever and bacteremia in two patients with symptomatic human immunodeficiency virus infection. the same organism was subsequently recovered from a bone marrow-transplant recipient with septicemia and from two immunocompetent persons with week-long febrile illnesses. all the patients recovered after antimicrobial therapy. | 1990 | 2233947 |
| [campylobacter pylori infection. results of an investigation of 130 patients]. | after recalling the main data on diagnosis, pathogenesis and treatment of cp infection, the results of a study on 130 patients are presented. | 1990 | 2234480 |
| do non-steroidal anti-inflammatory drugs or smoking predispose to helicobacter pylori infection? | susceptibility to helicobacter pylori infection is a poorly understood phenomenon. this study was undertaken to establish whether either smoking or chronic non-steroidal anti-inflammatory drug (nsaid) consumption might in some way predispose to h. pylori infection and hence lead to peptic ulceration. serological evidence of h. pylori infection was assessed in 100 consecutive subjects receiving nsaids without any evidence of gastrointestinal upset and 100 matched controls. all subjects had a full ... | 1990 | 2235801 |
| epidemiology in peptic ulcer disease. current status and future aspects. | peptic ulcer incidence is declining. a decreased prevalence of smokers together with other factors have contributed to this change. the widespread use of non-steroidal anti-inflammatory drugs (nsaid) has increased the incidence of ulcer in the older population and serious complications, such as perforation and bleeding, have been observed especially in older women. helicobacter pylori infection is virtually always present in duodenal and gastric ulcer and active chronic gastritis, but not prepyl ... | 1990 | 2237275 |
| helicobacter pylori: fact or fiction? | the recent isolation and classification of the spiral gastric bacteria helicobacter pylori has led to an explosion of worldwide research. the data strongly suggest that h. pylori is the causative agent for type-b active chronic gastritis. the role of h. pylori in duodenal ulcer awaits clarification, and, more importantly, potential treatment regimens need clear documentation and further detailed research. the past decade has revealed many intriguing facts about h. pylori infection. if, during th ... | 1990 | 2237277 |
| [the frequency of demonstration of campylobacter pylori]. | in 376 patients who underwent gastroscopy the presence of campylobacter pylori by microscopy, bacterial culture and urea test was studied. additionally, the histological examination of the antral mucosa was performed. the organisms were detected in 47.9% of the biopsy specimens (37.2% in normal endoscopic findings and 70% in duodenal ulcers). dependence on sex was not found and also no significant difference of campylobacter pylori detection in patients younger than 45 years compared with those ... | 1990 | 2238751 |
| elimination of helicobacter pylori under treatment with omeprazole. | biopsies from the stomachs (antrum and corpus) of 201 patients with peptic ulcers or reflux oesophagitis were retrospectively investigated for the effect of treatment with omeprazole on the elimination of helicobacter pylori (hp) and on gastritis. of 64 patients without gastritis two (3.1%) developed gastritis during treatment. among 134 patients with hp gastritis undergoing treatment, 48 (35.8%) experienced no hp elimination, in 41 (30.6%) there was hp elimination from the antrum, but hp persis ... | 1990 | 2238754 |
| [gastritis: immunohistochemical detection of specific and nonspecific immune response to helicobacter pylori]. | granulocyte infiltration was studied in 88 biopsies of antrum mucosa from patients with b-gastritis. evidence of iga-, igg- and igm-antibodies as well as of lysozyme in the mucosa was demonstrated by immunohistochemical methods. helicobacter pylori (hp) is coated by antibodies and a significant correlation between extent of opsonisation and number of plasma cells in the connective tissue of the lamina propria could be stated. thus, the infiltration of plasma cells is a specific immune response a ... | 1990 | 2238761 |
| [peptic ulcer and helicobacter pylori]. | | 1990 | 2240930 |
| seroprevalence of helicobacter pylori in seventh-day adventists and other groups in maryland. lack of association with diet. | to evaluate the possible role of diet in the transmission of helicobacter pylori, we compared h pylori seroprevalence among seventh-day adventists (who are vegetarian and abstain from alcohol, caffeine, and meat; n = 94) and two non-seventh-day adventist control groups (n = 168). with the use of an enzyme-linked immunosorbent assay h pylori antigen prepared in a french pressure cell, we found no difference in seroprevalence among these groups; however, seropositivity strongly correlated with age ... | 1990 | 2241444 |
| [helicobacter pylori, peptic diseases and colloid bismuth]. | | 1990 | 2244100 |
| helicobacter pylori infection and chronic gastritis: clinical, serological, and histologic correlations in children treated with amoxicillin and colloidal bismuth subcitrate. | twenty-three children with helicobacter (campylobacter) pylori-associated chronic gastritis are reported. family history of peptic disease, previous digestive procedures, and nonspecific epigastric pain were the most frequently encountered clinical features. antral nodularity at endoscopy and histologic evidence of follicular gastritis were characteristic morphological aspects. rapid urease tests suggested the diagnosis in 90% of patients. significant increases of serum igg and iga against helic ... | 1990 | 2246711 |
| helicobacter pylori and associated duodenal ulcer. | twenty three children with coexistent duodenal ulcer and helicobacter pylori infection were treated with either two weeks of amoxycillin (25 mg/kg/day) in addition to six weeks of cimetidine, or cimetidine alone. endoscopy with antral and duodenal biopsies for urease test, microaerophilic culture, and histological studies were performed at entry, six weeks, 12 weeks, and at six months. children with persistent h pylori infection at six weeks were given a further two weeks' course of amoxycillin. ... | 1990 | 2248531 |
| helicobacter pylori. | | 1990 | 2248546 |
| helicobacter pylori and gastric carcinoma. serum antibody prevalence in populations with contrasting cancer risks. | this investigation examined the correlation between helicobacter pylori (hp) infection, as reflected in immunoglobulin g serum antibodies, and the risk of gastric cancer. serum samples were obtained from populations with contrasting gastric cancer risks. the highest prevalence of hp infection, 93%, was observed in the adult population at highest gastric cancer risk, the residents of pasto, colombia. in the lower risk colombian city of cali, a 63% overall prevalence rate was found. both children ... | 1990 | 2249197 |
| [correlation between campylobacter pylori and chronic atrophic gastritis]. | the correlation between urease activity of campylobacter pylori and atrophic gastritis was studied. on the basis of fundamental study on the optimal ph of c. pylori urease activity, urease activity of 38 biopsied specimens were measured under ph 5 condition, and compared with the positive ratio of c. pylori. in this study, sensitivity was 86.7%, and specificity was 87.0%, respectively. mean urease activity of c. pylori positive specimens was 3.69 miu/mg protein, and under this condition, c. pylo ... | 1990 | 2250390 |
| [helicobacter pylori]. | ever since 1983 when marshall & warren succeeded in cultivating helicobacter pylori (hp) (previously known as campylobacter pylori) a high incidence thereof has been demonstrated in patients with ulcers and non-ulcerous dyspepsia. helicobacter pylori is easily diagnosed via microscopy, cultivation and serological tests. the bacterium may be treated with antibiotics or the ulcer drug bismuth subcitrate (de-nol). the pathogenetic role of hp is not clear. some studies have shown a lower recurrence ... | 1990 | 2251107 |
| [lymphocytic gastritis]. | lymphocytic gastritis is characterised by an accumulation of lymphocytes in the epithelium of the gastric mucosa. this form accounts for 4.5% of chronic b-gastritis and manifests itself by dyspepsia, anorexia and weight loss. the course is benign, as 12 of 19 patients recovered within 24 to 36 months in haot's studies. macroscopically it appears with nodules, erosions, thickened mucosal folds, or diffuse varioliform pattern. the gastric corpus is preferentially involved. the etiology is unknown. ... | 1990 | 2251461 |
| the who's and when's of therapy for helicobacter pylori. | | 1990 | 2252013 |
| helicobacter pylori infection: a simplified diagnostic approach. | we evaluated the diagnostic accuracy of endoscopic finding of nodular antritis and rapid urease test (rut) in order to simplify the approach to the diagnosis of helicobacter pylori (h. pylori) infection. forty-four consecutive patients (mean age 7.9 yr, range 6-13 yr) referred because of recurrent abdominal pain as the main symptom, were prospectively investigated for the presence of h. pylori. h. pylori positivity or negativity was defined as the concordance of two of the following tests: rut, ... | 1990 | 2252019 |
| helicobacter pylori infection in patients with acquired immune deficiency syndrome. | a controlled study was conducted on patients with human immunodeficiency virus (hiv) infection referred for upper endoscopy to evaluate the prevalence of helicobacter pylori (h. pylori) infection. four different stains and culture for h. pylori were performed on biopsy specimens from the gastric antrum. sixteen (40%) of 40 patients with acquired immune deficiency syndrome (aids) or aids-related complex (arc) were diagnosed to be infected with h. pylori versus 14 (39%) of 36 age-matched control p ... | 1990 | 2252020 |
| helicobacter (campylobacter) pylori: a new twist to an old disease. | | 1990 | 2252384 |
| medical treatment of antral gastrin cell hyperfunction: role of nonantisecretory therapy. | antral g cell hyperfunction (agch) is a rare condition, often associated with severe duodenal ulcer disease poorly responsive to medical therapy. up to now, no studies have been designed to investigate a possible role of medical treatment in the management of this syndrome. in this study we treated 9 agch patients with duodenal ulcer, unhealed with the prolonging standard doses of h2 antagonists (300 mg/day ranitidine or 800 mg/day cimetidine), with a nonantacid therapy, tripotassium dicitrato b ... | 1990 | 2253824 |
| relation of helicobacter pylori to the human gastric mucosa in chronic gastritis of the antrum. | the spatial relations between bacteria and the affected tissues can indicate pathogenic mechanisms. this study was undertaken to define the spatial relation of helicobacter pylori to the human gastric mucosa. antibodies against gastric mucus and ruthenium red were used to stabilise the glycoprotein structure of the mucus and glycocalyces in antral biopsy specimens from eight patients infected with h pylori. the location of organisms and ultrastructural features were assessed using systematic sca ... | 1990 | 2253904 |
| evaluation of 13c-urea breath test in the detection of helicobacter pylori and in monitoring the effect of tripotassium dicitratobismuthate in non-ulcer dyspepsia. | sixty nine patients with non-ulcer dyspepsia have been studied with endoscopy, biopsy, quick urease (clo) test, helicobacter pylori culture, and the 13c-urea breath test before and after treatment with tripotassium dicitratobismuthane (denol) two tablets twice daily for four weeks. symptoms of non-ulcer dyspepsia were recorded using a standard questionnaire. using h pylori culture as the gold standard, the sensitivity of the 13c-urea breath test was 90%, the specificity 98.6%, and the accuracy 9 ... | 1990 | 2253905 |
| paf-acether synthesis by helicobacter pylori. | clinical studies suggest that helicobacter pylori may play a role in the pathogenesis of gastroduodenal ulcers in man but direct evidence of mucosal injury by this microorganism is still lacking. paf-acether (paf) causes a number of disorders including ischaemic bowel necrosis and gastroduodenal ulceration. since paf is produced by escherichia coli, we investigated whether it could be synthesised by h pylori. five h pylori isolates were collected from antral biopsy specimens from patients with g ... | 1990 | 2253906 |
| the efficacy of furazolidone and metronidazole in the treatment of chronic gastritis associated with helicobacter (campylobacter) pylori--a randomized double-blind placebo-controlled clinical trial. | seventy-two patients with helicobacter pylori-associated chronic gastritis were randomized to a 3-week oral treatment with furazolidone 0.1g t.i.d. or metronidazole 0.2g t.i.d. or placebo. endoscopy was performed before and after treatment, and biopsy specimens were taken from the antrum of the stomach for histological examination and culture of helicobacter pylori. disappearance rates of helicobacter pylori in furazolidone, metronidazole and the control groups were 74% (20/27) if considering co ... | 1990 | 2253927 |
| [campylobacter pylori--its role in diseases of the upper digestive tract. the present and future]. | in the paper an outline of modern knowledge is presented on campylobacter pylori (helicobacter pylori) which participates in certain upper digestive tract diseases. the history is described of studies on this organism and modern methods of its identification are discussed. the sites of presence of this microorganism are presented in the upper part of the digestive tract and the diseases of this part of the digestive tract are described which are associated with the presence of campylobacter pylo ... | 1990 | 2256330 |
| histologic characteristics of campylobacter pylori (helicobacter pylori) mediated gastritis. | one hundred-nineteen specimens were reviewed to determine whether or not there were histologic changes specific for campylobacter pylori (cp), (helicobacter pylori) mediated gastritis. hematoxylin and eosin (h&e), brown-hopp, and wright-giemsa stained sections were examined independently by two pathologists for (a) the presence of acute cryptitis, (b) percent and degree of crypt involvement, and (c) spectrum of inflammatory cells within the lamina propriae. the amount of mucus was quantified on ... | 1990 | 2256661 |
| nsaid associated gastritis and helicobacter pylori. | | 1990 | 2257005 |
| inhibition of helicobacter pylori haemagglutination activity by human salivary mucins. | thirty isolates of helicobacter pylori from gastric biopsies agglutinated human erythrocyte suspensions. crude mucin preparations derived from saliva of 20 different donors were examined for their ability to inhibit haemagglutination. all mucin preparations exhibited strong inhibitory activity. removal of sialic residues from mucin preparations by treatment with neuraminidase resulted in a substantial reduction of their inhibitory activity. the mucin preparations had no bactericidal or aggregati ... | 1990 | 2257167 |
| seroepidemiology of helicobacter pylori infection in greece. | helicobacter pylori infection is strongly associated with chronic gastritis and peptic ulceration. as the prevalence of h. pylori infection in southern european populations is not known, a serological survey of 1069 samples from three different age groups in the greek population was carried out with an enzyme-linked immunosorbent assay (elisa) for antibodies to these bacteria. the antigen was an ultracentrifuged supernate of whole cell sonicates of 5 isolates of h. pylori assessed by electrophor ... | 1990 | 2257168 |
| helicobacter pylori in its lair: a role in ulcer recurrence? | | 1990 | 2258209 |
| isolation of helicobacter pylori from dental plaques in healthy volunteers. | the presence of helicobacter pylori (h pylori) was looked for in dental plaques of 40 healthy volunteers by clo test, culture and smear stained with warthin-starry stain. h pylori was found to be present in the dental plaques of all 40 volunteers. the dental plaque is an important reservoir of h pylori. | 1990 | 2258210 |
| prevalence of helicobacter pylori in symptomatic patients undergoing gastrointestinal endoscopy. | | 1990 | 2258222 |
| soluble and cell-associated haemagglutinins of helicobacter (campylobacter) pylori. | some plate-grown strains of helicobacter (campylobacter) pylori that were harvested into phosphate-buffered saline and left for 1 h released soluble haemagglutinins. these caused high-titre agglutination of human and guinea-pig erythrocytes, whereas chicken, sheep and bovine erythrocytes were agglutinated at various titres. six of 10 strains which had been subcultured repeatedly did not possess soluble haemagglutinins. slide agglutination of bacterial suspensions demarcated the strains into two ... | 1990 | 2258915 |
| [detection of campylobacter pylori in patients with peptic ulcer as a criterion of the effectiveness of treatment with ultraviolet laser irradiation]. | | 1990 | 2259116 |
| [the role of campylobacter pylori in lesions of the upper segments of the digestive tract in children]. | | 1990 | 2259589 |
| antigenicity of fractions of helicobacter pylori prepared by fast protein liquid chromatography and urease captured by monoclonal antibodies. | the antigenicity of helicobacter pylori protein fractions separated by fast protein liquid chromatography size exclusion was investigated by eia with sera from patients of well defined helicobacter pylori status. the antigenic material of helicobacter pylori was confined to fractions 8 and 14 to 21. urease containing fractions (14/15) and flagella containing fractions (17/18) were identified. fraction 8 non-specifically bound human immunoglobulin as demonstrated by the binding of helicobacter py ... | 1990 | 2261918 |
| the occurrence and extent of helicobacter pylori colonization and antral and body gastritis profiles in an estonian population sample. | a series of 143 subjects representing an estonian urban population was examined for the occurrence and extent (absent, mild, moderate, severe) of helicobacter pylori colonization in antral and body biopsy specimens (giemsa staining). these data were correlated with the presence and grade of chronic gastritis (normal, mild, moderate, or severe superficial chronic gastritis; mild, moderate, or severe atrophic gastritis) in the antrum and the body. gastritis of any grade was found in the antrum and ... | 1990 | 2263873 |
| helicobacter pylori infection and atrophic gastritis in the elderly. | | 1990 | 2264888 |
| systemic chemotherapy for helicobacter pylori eradication? | | 1990 | 2265791 |
| gastric epithelium in the duodenum: its association with helicobacter pylori and inflammation. | duodenal biopsy specimens from 471 adults and 47 children were examined to determine the prevalence and distribution of gastric epithelium in the duodenal bulb in relation to age, gender, gastroduodenal inflammation, smoking, alcohol and consumption of nonsteroidal anti-inflammatory drugs (nsaid). gastric metaplasia was present in the anterior wall duodenal biopsy specimen in 31%, was significantly less common in patients under 17 than in adults, and was more common in males than females. in six ... | 1990 | 2266184 |
| helicobacter pylori in dyspeptic patients in kuwait. | two hundred and four patients, mainly arabs, attending for upper gastrointestinal endoscopy at the gastroenterology clinic in mubarak al-kabeer hospital, kuwait, were examined for evidence of infection with helicobacter pylori and associated inflammation. biopsy specimens of antrum, body, and duodenum; gastric juice; and antral mucosal brushings were investigated by microbiological, cytological, and histopathological methods. clinical conditions diagnosed at endoscopy included gastritis, gastric ... | 1990 | 2266185 |
| helicobacter pylori infection of gastric mucin cell metaplasia: the duodenum revisited. | the histological material of 158 billroth ii gastrectomy specimens, used for a former study that established a relationship between duodenal ulcers and the presence of gastric metaplastic epithelium in the duodenal bulb, was reinvestigated for the presence of helicobacter pylori. the results show that in all duodenal ulcer patients with gastric mucin cell metaplasia h. pylori colonized the metaplastic epithelium accompanied by an inflammatory response. the intestinal mucosa was always negative f ... | 1990 | 2266461 |
| [comparison of colloidal bismuth subcitrate with ranitidine in healing and relapse of campylobacter pylori-associated duodenal ulcers]. | eighty patients with campylobacter pylori-associated duodenal ulcer disease were randomly allocated to receive colloidal bismuth subcitrate (cbs)tablet 120 mg four times a day or ranitidine 150 mg twice daily in a trial comparing the effects of these drugs in short-term healing and post-healing relapse rates of duodenal ulceration. at 8 weeks 88.1% (37/42) of those on cbs and 92.1% (35/38) of those on ranitidine had ulcers healed. the difference is not significant. after ulcer healing, the cumul ... | 1990 | 2269032 |
| investigation of the structure and localization of the urease of helicobacter pylori using monoclonal antibodies. | the urease of helicobacter pylori (formerly campylobacter pylori) has been partly purified by fast protein liquid chromatography. this material contained 10 nm doughnut-like structures when examined by electron microscopy and comprised three major polypeptides (61 kda, 56 kda and 28 kda). only two of these polypeptides (61 kda and 28 kda) were observed in urease-containing material isolated by preparative non-denatured page. monoclonal antibodies (mabs) were produced which were directed against ... | 1990 | 2269872 |
| biochemical changes induced by campylobacter pylori in the gastric juice. | the biochemical changes induced in the gastric juice by the presence of campylobacter pylori (cp) were followed up in 151 patients with various gastric and duodenal diseases. the diagnosis of cp infection was made by the urease test. in the presence of cp urea decreased in the gastric juice and ammonia increased. the sialic acid, fucose and hexoses, glucide components of the mucus glycoproteins dissolved in the gastric juice, underwent no change in the presence of cp. the hexosamines in the gast ... | 1990 | 2270423 |
| helicobacter pylori: its role in gastric disease. | | 1990 | 2272122 |
| [primary peptic ulcer in infancy and childhood. personal experience]. | we report a retrospective review of primary peptic ulcer peptic disease in 61 children. the follow-up period ranged from 1 month to 6 years. all cases were confirmed by endoscopic examination and related with radiological studies result. the number of ulcer peptic disease detected increased as much as the number of endoscopies were performed annually. in the last 20 patients pinch biopsies from antrum were taken looking for campylobacter pylori, encountering 10 positives. the relation male:femal ... | 1990 | 2275489 |
| [14c-urea breath test to diagnose gastric helicobacter pylori colonization]. | helicobacter pylori (h. pylori), ex-campylobacter pylori, is now considered to be the causative agent of active chronic gastritis in humans and may be diagnosed by histology, gram-stain, culture, urease test or noninvasively by 14c-urea breath test. the aim of this study was to determine the sensitivity, specificity, and reproducibility of the breath test as compared with the microbiological (culture) "gold standard". forty-one subjects were studied. gastroscopy was performed in all participants ... | 1990 | 2276558 |
| [human chronic gastritis associated with non-helicobacter pylori spiral organisms (gastrospirillum hominis). four cases and review of the literature]. | four cases of human active chronic gastritis associated with gastrospirillum hominis, a recently described spiral shaped organism are presented. these 4 cases originated from a series of 1976 consecutive gastric biopsies, i.e. a prevalence of 0.25 percent in our material, are compared with helicobacter pylori prevalence of 45 percent. histopathological findings were chronic active gastritis with mild or no atrophy. electron microscopy showed spiral bacteria with terminal flagellae, identical to ... | 1990 | 2276559 |
| identification of flagellar and associated polypeptides of helicobacter (formerly campylobacter) pylori. | flagella of helicobacter pylori were isolated from intact organisms by shearing and differential centrifugation. treatment of the flagella with the detergent triton x-100 removed the flagellar sheath, which was confirmed by electron microscopy, and the remaining naked flagella were shown by sodium dodecyl sulphate polyacrylamide gel electrophoresis (sds-page) to consist primarily of a single 54 kilodalton (kda) polypeptide. this was confirmed by immunogold labelling and electron microscopy of de ... | 1990 | 2276611 |
| upper gastrointestinal manifestations in rheumatoid arthritis patients: intrinsic or extrinsic pathogenesis? | apart from the complication of gastrointestinal vasculitis it is not known whether the upper gastrointestinal (ugi) tract has any special disease characteristics in rheumatoid arthritis (ra). however, oesophageal motility disorders have been reported in 30% of ra patients. hypergastrinaemia has been found in 23-43% of ra patients, usually in combination with a decreased gastric acid output. another finding suggestive of a decreased secretory state, namely a decreased level of pepsinogen a, was f ... | 1990 | 2277973 |
| plastic bag precautions during testing for helicobacter pylori. | | 1990 | 2279674 |
| serodiagnosis of helicobacter pylori infection in childhood. | sera from 100 children (ages, 6 to 16 years) presenting with upper gastrointestinal symptoms were examined for antibodies to helicobacter pylori by enzyme-linked immunosorbent assay (elisa) based on crude, loosely cell-associated antigens and a partially purified urease antigen preparation. all children underwent endoscopy, and 20 children were shown to have h. pylori infection by histology or direct culture. serum anti-h. pylori immunoglobulin g (igg) levels (crude antigen) were clearly raised ... | 1990 | 2279995 |