| spread of poliovirus infection during an epidemic of unusual severity, woodbury county iowa, and dakota county, nebraska, 1952. | | 1957 | 13424523 |
| social patterns of antibody to poliovirus. | | 1957 | 13417596 |
| observations on natural poliovirus infections in immunized children. | | 1957 | 13411317 |
| poliomyelitis: comparison of responses of vaccinated and naturally immune humans to ingestion of attenuated poliovirus. | | 1957 | 13496118 |
| antigenic potency of poliovirus vaccines. | | 1956 | 13362234 |
| poliovirus antibody in children in northern ireland. | | 1956 | 13307971 |
| some physiologic aspects of poliovirus infections. | | 2006 | 13512849 |
| the diagnosis of atypical poliovirus infection. | | 1956 | 13409456 |
| the modification of poliovirus antigens by heat and ultraviolet light. | | 1955 | 13272322 |
| [chances of recovery of the muscles poliovirus]. | | 2016 | 13246175 |
| [the problem of poliovirus]. | | 1949 | 15392267 |
| enhancing viral vaccine production using engineered knockout vero cell lines - a second look. | the global adoption of vaccines to combat disease is hampered by the high cost of vaccine manufacturing. the work described herein follows two previous publications (van der sanden et al., 2016; wu et al., 2017) that report a strategy to enhance poliovirus and rotavirus vaccine production through genetic modification of the vero cell lines used in large-scale vaccine manufacturing. crispr/cas9 gene editing tools were used to knockout vero target genes previously shown to play a role in polio- an ... | 2018 | 29555218 |
| a method for recovery of poliovirus 1 from a variety of foods. | a method was developed for the recovery of low numbers of plaque-forming units (pfu) of inoculated poliovirus type 1 from seven different foods. viruses were eluted at ph 9.0 from 25-g food test portions, concentrated at ph 4.5, and eluted at ph 7.5. the final eluates were assayed for pfu in african green monkey kidney (bgm) cell monolayers. the average virus input ranged from 55 to 79 pfu per unit portion. the average percent recoveries were as follows: potato salad, 61; radishes, 54; celery, 4 ... | 1986 | 30959716 |
| effects of storage in recovery media on sublethally heated polio and echo viruses. | in vitro renaturation of heat-denatured virus particles was studied using poliovirus type 1, strain chat and echovirus type 6, strain d'amori. six recovery media were chosen to simulate heat-processed foods and mildly processed or raw foods and to represent a range of compositions. virus was suspended in four heating media and processed to various degrees of inactivation. after cooling, the stressed virus was resuspended in the recovery media and incubated at 30 c for up to 7 days. titers were d ... | 1981 | 30856757 |
| comparative evaluation of prophylactic siv vaccination modalities administered to the oral cavity. | attempts to develop a protective human immunodeficiency virus (hiv) vaccine have had limited success, especially in terms of inducing protective antibodies capable of neutralizing different viral strains. as hiv transmission occurs mainly via mucosal surfaces, hiv replicates significantly in the gastrointestinal tract, and the oral route of vaccination is a very convenient one to implement worldwide, we explored three siv vaccine modalities administered orally and composed of simian immunodefici ... | 2020 | 32962398 |
| immune priming and long-term persistence of memory b cells after inactivated poliovirus vaccine in macaque models: support for at least 2 doses. | as a risk-mitigation strategy to minimize paralytic polio following withdrawal of sabin type 2 from the oral poliovirus vaccine in april 2016, a single full dose or 2 fractional doses of inactivated poliovirus vaccine (ipv) are recommended. however, limited knowledge exists on long-term persistence of immune memory following 1- or 2-dose ipv schedules. | 2018 | 30376091 |
| newcastle disease virus-based vectored vaccine against poliomyelitis. | the poliovirus eradication initiative has spawned global immunization infrastructure and dramatically decreased the prevalence of the disease, yet the original virus eradication goal has not been met. the suboptimal properties of the existing vaccines are among the major reasons why the program has repeatedly missed eradication deadlines. oral live poliovirus vaccine (opv), while affordable and effective, occasionally causes the disease in the primary recipients, and the attenuated viruses rapid ... | 2018 | 29925653 |
| [experience of application of igy-technology for laboratory diagnostics of viral infections.] | the well-known advantages of class y antibodies (igy) from egg yolks of immunized hens in comparison with class g antibodies (igg) of laboratory animals traditionally used in laboratory diagnosis of infectious diseases determine the stable interest of researchers in using igy for these purposes (igy technology). over the past 20 years, the obvious benefits of igy technology have been demonstrated for a number of viral and bacterial infections. goals and objectives. construction of elisa systems ... | 2020 | 32496717 |
| poliovirus-binding inhibition elisa based on specific chicken egg yolk antibodies as an alternative to the neutralization test. | the first application results of enzyme immunoassay system (elisa) - binding inhibition elisa (bi elisa) for the detection of antibodies to polioviruses of three types based on the use of specific antibodies from chicken yolk (igy) are presented. this variant of elisa is a "surrogate" neutralization test (nt). when comparing the results of the detection of antibodies in 90 sera of children who were vaccinated with oral and inactivated poliovirus vaccines, good correlation (r = 0.67, 0.61, 0.76 f ... | 2019 | 30660606 |
| lack of molecular mimicry between nonhuman primates and infectious pathogens: the possible genetic bases. | recently, it was found that proteomes from poliovirus, measles virus, dengue virus, and severe acute respiratory syndrome-related coronavirus 2 (sars-cov-2) have high molecular mimicry at the heptapeptide level with the human proteome, while heptapeptide commonality is minimal or absent with proteomes from nonhuman primates, that is, gorilla, chimpanzee, and rhesus macaque. to acquire more data on the issue, analyses here have been expanded to ebola virus, francisella tularensis , human immunode ... | 2021 | 33748822 |
| development of anti-human t cell immunoreceptor with ig and itim domains (tigit) monoclonal antibodies for flow cytometry. | immune checkpoint inhibitors targeting programmed cell death-ligand 1 (pd-l1), programmed cell death-1 (pd-1), and cytotoxic t lymphocyte-associated antigen 4 (ctla-4) recently made a significant survival rate improvement in cancer treatment. t cell immunoreceptor with ig and itim domains (tigit) is expressed in t and nk cells related to their activities. it has a single extracellular immunoglobulin domain, a type 1 transmembrane domain, and a single intracellular itim. tigit binds with poliovir ... | 2021 | 33900817 |
| oral vaccination approaches for anti-shiv immunity. | we modified a sabin oral poliovirus vaccine (opv) vector to permit secretion of the antigens of interest with the goal of improving anti-hiv env humoral responses in a shiv mucosal immunization composed of dna and recombinant opvs. we evaluated stimulation of systemic and mucosal cell-mediated and humoral immunity in rhesus macaques by two regimens, both involving a prime with a shivbg505 dna construct producing non-infectious particles formulated in lipid nanoparticles, administered in the oral ... | 2021 | 34234789 |