Publications

TitleAbstractYear
Filter
PMID
Filter
the effects of plant essential oils on escape response and mortality rate of aedes aegypti and anopheles minimus.the high throughput screening system (hitss) has been applied in insecticide behavioral response studies with various mosquito species. in general, chemical or natural compounds can produce a range of insect responses: contact irritancy, spatial repellency, knock-down, and toxicity. this study characterized these actions in essential oils derived from citronella, hairy basil, catnip, and vetiver in comparison to deet and picaridin against aedes aegypti and anopheles minimus mosquito populations. ...201526611967
intraspecific variation in desiccation survival time of aedes aegypti (l.) mosquito eggs of australian origin.aedes aegypti (l.) mosquitoes preferentially oviposit in natural and artificial receptacles where their eggs are able to withstand drying as water levels fluctuate. desiccation-resistant eggs also increase the potential for establishment in non-native habitats while providing logistical impediments to control programs. viability and mean survival times of eggs stored under three dryness conditions for up to 367 days were investigated among three field-derived colonies of australian ae. aegypti t ...201526611964
mosquito salivary allergen aed a 3: cloning, comprehensive molecular analysis, and clinical evaluation.allergic reactions to mosquito bites are an increasing clinical concern. due to the lack of availability of mosquito salivary allergens, they are underdiagnosed. here, we reported a newly cloned mosquito aedes (ae.) aegypti salivary allergen.201626608594
trace samples of human blood in mosquitoes as a forensic investigation tool.investigations of any type of crime invariably starts at the crime scene by collecting evidence. thus, the purpose of this research was to collect and analyze an entomological trace from an environment that is similar to those of indoor crime scenes. hematophagous mosquitoes were collected from two residential units; saliva of volunteers that were residents in the units was also collected for genetic analysis as reference samples. we examined the allele frequencies of 15 short tandem repeat loci ...201526600546
a novel in vitro bioassay to explore the repellent effects of compounds against mosquito aedes aegypti (diptera: culicidae).mosquitoes are vectors for many pathogens resulting in many deaths of humans. repellents play an important role in reducing mosquito bites and the spread of mosquito-borne diseases. currently, klun & debboun (k & d) and human-arm-based bioassay systems are used to identify repellent properties of compounds, extracts, and essential oils. risks involved with human-arm-based systems are allergic reactions and limited replicates. we are reporting an in vitro bioassay method “ncnpr repellent bioassay ...201626590191
the use of a chemically defined artificial diet as a tool to study aedes aegypti physiology.aedes aegypti mosquitoes obtain from vertebrate blood nutrients that are essential to oogenesis, such as proteins and lipids. as with all insects, mosquitoes do not synthesize cholesterol but take it from the diet. here, we used a chemically defined artificial diet, hereafter referred to as substitute blood meal (sbm), that was supplemented with cholesterol to test the nutritional role of cholesterol. sbm-fed and blood-fed mosquitoes were compared regarding several aspects of the insect physiolo ...201526578294
spatial and temporal variation in aedes aegypti and aedes albopictus (diptera: culicidae) numbers in the yogyakarta area of java, indonesia, with implications for wolbachia releases.of mosquito vector populations, particularly through wolbachia endosymbionts. the success of these strategies depends on understanding the dynamics of vector populations. in preparation for wolbachia releases around yogyakarta, we have studied aedes populations in five hamlets. adult monitoring with biogent- sentinel (bg-s) traps indicated that hamlet populations had different dynamics across the year; while there was an increase in aedes aegypti (l.) and aedes albopictus (skuse) numbers in the ...201626576934
identification of a major quantitative trait locus determining resistance to the organophosphate temephos in the dengue vector mosquito aedes aegypti.organophosphate insecticides (op) have extensively been used to control mosquitoes, such as the vector aedes aegypti. unfortunately, op resistance has hampered control programs worldwide. we used quantitative trait locus (qtl) mapping to evaluate temephos resistance in two f1 intercross populations derived from crosses between a resistant ae. aegypti strain (recr) and two susceptible strains (moyod and red). a single major effect qtl was identified on chromosome 2 of both segregating populations ...201626576515
characterization and mosquitocidal potential of neem cake-synthesized silver nanoparticles: genotoxicity and impact on predation efficiency of mosquito natural enemies.mosquitoes (diptera: culicidae) serve as important vectors for a wide number of parasites and pathogens of huge medical and veterinary importance. aedes aegypti is a primary dengue vector in tropical and subtropical urban areas. there is an urgent need to develop eco-friendly mosquitocides. in this study, silver nanoparticles (agnp) were biosynthesized using neem cake, a by-product of the neem oil extraction from the seed kernels of azadirachta indica. agnp were characterized using a variety of ...201626573518
the impact of indoor residual spraying of deltamethrin on dengue vector populations in the peruvian amazon.dengue is an important public health problem in the amazon area of peru, resulting in significant morbidity each year. as in other areas of the world, ultra-low volume (ulv) application of insecticides is the main strategy to reduce adult populations of the dengue vector aedes aegypti, despite growing evidence of its limitations as a single control method. this study investigated the efficacy of deltamethrin s.c. applied through indoor residual spraying (irs) of dwellings in reducing a. aegypti ...201626571068
how important is vertical transmission of dengue viruses by mosquitoes (diptera: culicidae)?vertical transmission of dengue viruses by mosquitoes was discovered at the end of the late 1970s and has been suggested to be a means by which these viruses persist. however, it is unclear how widespread it is in nature, and its importance in the epidemiology of this disease is still debated. here, we review the literature on vertical transmission and discuss its role in dengue's epidemiology and control. we conclude that given the number of studies that failed to find evidence of vertical tran ...201626545718
satyrization and satyrization-resistance in competitive displacements of invasive mosquito species.competitive displacements or reductions of resident populations of insects, often effected by a related species, may be caused by a variety of mechanisms. satyrization is a form of mating interference in which males of one species mate with females of another species, significantly decreasing their fitness and not generating hybrids. satyrization has been established to be the probable cause of competitive displacements of resident mosquitoes by invasive species, especially of aedes aegypti by a ...201626542083
plant-mediated biosynthesis of nanoparticles as an emerging tool against mosquitoes of medical and veterinary importance: a review.mosquitoes (diptera: culicidae) are a key threat for millions of people worldwide, since they act as vectors for devastating parasites and pathogens. mosquito young instars are usually targeted with organophosphates, insect growth regulators and microbial control agents. indoors residual spraying and insecticide-treated bed nets are also employed. however, these chemicals have strong negative effects on human health and the environment. newer and safer tools have been recently implemented to enh ...201626541154
nepenthes ampullaria (nepenthaceae) pitchers are unattractive to gravid aedes aegypti and aedes albopictus (diptera: culicidae).nepenthes pitcher plants are colonized by a variety of specialized arthropods. as aedes mosquitoes are container breeders, nepenthes pitchers are a potential candidate oviposition site for vector species, such as aedes aegypti (l.) and aedes albopictus (skuse). however, aedes spp. are not commonly encountered in nepenthes pitchers, and the environment inside the pitchers of some species is lethal to them. one exception is nepenthes ampullaria jack, whose pitchers are known to be colonized by ae. ...201626518035
phenotypic and genotypic profile of pyrethroid resistance in populations of the mosquito aedes aegypti from goiânia, central west brazil.the mosquito aedes aegypti has evolved resistance to pyrethroid insecticides. the present study evaluated ae. aegypti from goiânia for the resistant phenotype and for mutations associated with resistance.201526516973
physical features and chitin content of eggs from the mosquito vectors aedes aegypti, anopheles aquasalis and culex quinquefasciatus: connection with distinct levels of resistance to desiccation.mosquito eggs are laid in water but freshly laid eggs are susceptible to dehydration, if their surroundings dry out at the first hours of development. during embryogenesis of different mosquito vectors the serosal cuticle, an extracellular matrix, is produced; it wraps the whole embryo and becomes part of the eggshell. this cuticle is an essential component of the egg resistance to desiccation (erd). however, erd is variable among species, sustaining egg viability for different periods of time. ...201526514070
the siren's song: exploitation of female flight tones to passively capture male aedes aegypti (diptera: culicidae).the need to capture male mosquitoes has intensified recently as a result of a number of male-based sterile insect technique (sit) and population-modification programs focused on aedes aegypti (l.) having initiated field releases. here, we report the results of the successful exploitation of the attraction of male ae. aegypti to female flight tones to enhance male collections in nonmechanical passive (nonbattery powered) gravid aedes traps (gat). prior to field studies, male attraction to female ...201626502754
the influence of ambient temperature on the susceptibility of aedes aegypti (diptera: culicidae) to the pyrethroid insecticide permethrin.insecticides are the most common strategy used for the management of mosquitoes. changes in ambient temperature can alter the toxicity of insecticides to ectothermic organisms. studies show organophosphate insecticides exhibit a positive correlation between ambient temperature and mortality for many insect species, and carbamate insecticides exhibit a slightly negative correlation between ambient temperature and mortality. pyrethroid insecticides exhibit a distinctly negative correlation between ...201626477050
comparison of field and laboratory-based tests for behavioral response of aedes aegypti (diptera: culicidae) to repellents.the repellent and irritant effects of three essential oils-clove, hairy basil, and sweet basil-were compared using an excito-repellency test system against an insecticide-resistant strain of aedes aegypti (l.) females from pu teuy, kanchanaburi province. deet was used as the comparison standard compound. tests were conducted under field and controlled laboratory conditions. the most marked repellent effect (spatial noncontact assay) among the three test essential oils was exhibited by sweet basi ...201526470388
larvicidal activity of pereskia bleo (kunth) dc. (cactaceae) fruit endocarp crude and fractionated extracts against aedes aegypti (l.) (diptera: culicidae).the use of insecticides can cause adverse effects in vector control, a plant bio-insecticide is an advantageous substitute. currently, the promising mosquito larvicidal activity from plant extracts has been reported worldwide, including thailand. in this study, the endocarp of pereskia bleo (kunth) dc. fruit was extracted with distilled water and ethanol. crudes and fractionated groups of the extracts were evaluated for their larvicidal efficacy against the 3rd instar larvae of aedes aegypti. at ...201426466415
a simple and affordable membrane-feeding method for aedes aegpyti and anopheles minimus (diptera: culicidae).this study developed an artificial feeding (af) method to replace direct host feeding (dhf) for the maintenance of aedes aegypti and anopheles minimus mosquito colonies. the procedure can be adopted by all laboratories due to its simple and affordable materials and design. the apparatus consists of heparinized cow blood contained in a 5cm diameter glass petri dish with 5cm(2) parafilm m (bemis(®)) stretched thinly over the top, with a pre-heated bag of vegetable oil placed underneath to keep the ...201526440474
control of aedes aegypti and ae. albopictus, the vectors of dengue and chikungunya, by using pheromone c21 with an insect growth regulator: results of multicentric trials from 2007-12 in india.aedes mosquito control has gained much importance nowadays in view of rise in number of reported cases of dengue and chikungunya in india and other countries. in the present study, c21 attracticide (containing a pheromone and an insect growth regulator—igr, developed by defence research and development establishment (drde), gwalior, india was tested for its feasibility for surveillance and control of aedes mosquito in a multicentric mode from october 2007 to june 2012 in urban (delhi, and bengal ...201526418653
toxicity of cephalaria species and their individual constituents against aedes aegypti.crude acetone and ethanol extracts of the aerial parts of 21 cephalaria species collected from turkey were investigated for larvicidal and adult topical activity against aedes aegypti. the ethanol extracts from c. elazigensis var. purpurea, c. anatolica, and c. elmaliensis possessed the highest mortality against first instar ae. aegypti larvae. luteolin-7-o-β-d-glycoside (1), isolated from c. elmaliensis ethanol extract, demonstrated 33% and 53% mortality at 0.1 μg/ml concentration against first ...201526411009
spectral and hrtem analyses of annona muricata leaf extract mediated silver nanoparticles and its larvicidal efficacy against three mosquito vectors anopheles stephensi, culex quinquefasciatus, and aedes aegypti.mosquitoes transmit various diseases which mainly affect the human beings and every year cause millions of deaths globally. currently available chemical and synthetic mosquitocidal agents pose severe side effects, pollute the environment vigorously, and become resistance. there is an urgent need to identify and develop the cost effective, compatible and eco-friendly product for mosquito control. the present study was aimed to find out the larvicidal potential of aqueous crude extract and green s ...201526410042
multi-cue integration: how female mosquitoes locate a human host.to reproduce, the female yellow fever mosquito has to find a human host. there are many potential cues available to guide such navigation: exhaled carbon dioxide, a plethora of skin odors, the host's visual and heat signatures and, close by, moisture. recent work is shedding new light on how these are integrated by the mosquito in targeting a human host.201526394099
modification of the suna trap for improved survival and quality of mosquitoes in support of epidemiological studies.monitoring adult mosquito populations provides information that is critical for assessing risk of vector-borne disease transmission. the recently developed suna trap was found to be a very effective trap when baited with an attractive odor blend. a modification of this trap was tested to improve its function as a tool for monitoring mosquito populations, including anopheles coluzzii (an. gambiae sensu stricto molecular form m), aedes aegypti, and culex pipiens. the modified suna trap (suna-m) wa ...201526375903
schools as potential risk sites for vector-borne disease transmission: mosquito vectors in rural schools in two municipalities in colombia.dengue and other vector-borne diseases are of great public health importance in colombia. vector surveillance and control activities are often focused at the household level. little is known about the importance of nonhousehold sites, including schools, in maintaining vector-borne disease transmission. the objectives of this paper were to determine the mosquito species composition in rural schools in 2 municipalities in colombia and to assess the potential risk of vector-borne disease transmissi ...201526375902
a multiobjective optimization approach for combating aedes aegypti using chemical and biological alternated step-size control.dengue epidemics, one of the most important viral disease worldwide, can be prevented by combating the transmission vector aedes aegypti. in support of this aim, this article proposes to analyze the dengue vector control problem in a multiobjective optimization approach, in which the intention is to minimize both social and economic costs, using a dynamic mathematical model representing the mosquitoes' population. it consists in finding optimal alternated step-size control policies combining che ...201526362231
improving the effectiveness of three essential oils against aedes aegypti (linn.) and anopheles dirus (peyton and harrison).repellency of essential oil extracted from curcuma longa, eucalyptus globulus, and citrus aurantium at various concentrations (5, 10, 15, 20, and 25 %) with and without 5 % vanillin was evaluated against female mosquitoes: aedes aegypti and anopheles dirus. the comparisons were made with a commercial chemical repellent (n,n-diethyl-3-methylbenzamide (deet) 25 % w/w; kor yor 15) by arm in cage method. it was found that the essential oils with 5 % vanillin gave the longest lasting period against t ...201626358103
studies on insecticide susceptibility of aedes aegypti (linn) and aedes albopictus (skuse) vectors of dengue and chikungunya in andaman and nicobar islands, india.dengue and chikungunya are important arboviral infections in the andaman islands. competent vectors viz. aedes aegypti and aedes albopictus are widely prevalent. the most effective proven method for interrupting the transmission of these arboviruses is vector control, mediated through insecticides. currently, ddt and temephos are the insecticides used for vector control in these islands. lack of information on susceptibility necessitated assessing the susceptibility profile of a. aegypti and a. ...201526344869
identification and characterization of novel membrane-bound prl protein tyrosine phosphatases from setaria cervi, a bovine filarial parasite.a significant amount of protein tyrosine phosphatase (ptp) activity was detected in the detergent-soluble membrane-bound fraction of setaria cervi, a bovine filarial parasite. the membrane-bound ptp activity was significantly inhibited when the adult parasites were exposed to compounds having antifilarial activity like aspirin and sk7 as well as phenylarsine oxide, a specific ptp inhibitor suggesting that this activity is stress regulated. further, this enzyme was purified as a single protein of ...201526341797
efficacy of essential oil from cananga odorata (lamk.) hook.f. & thomson (annonaceae) against three mosquito species aedes aegypti (l.), anopheles dirus (peyton and harrison), and culex quinquefasciatus (say).the essential oil of cananga odorata flowers was evaluated for oviposition-deterrent, ovicidal, insecticidal, and repellent activities toward three mosquito species: aedes aegypti, anopheles dirus, and culex quinquefasciatus. oviposition deterrence of the oil was evaluated on gravid females using oviposition deterrence bioassay. the results showed that 10 % ca. odorata exhibited high percent effective repellency against oviposition at 99.4 % to ae. aegypti, 97.1 % to an. dirus, and 100 % to cx. ...201526337270
evaluation of insect growth regulators against field-collected aedes aegypti and aedes albopictus (diptera: culicidae) from malaysia.susceptibility status of aedes aegypti (l.) and aedes albopictus skuse larvae obtained from 12 states in malaysia were evaluated against five insect growth regulators (igrs), namely, pyriproxyfen, methoprene, diflubenzuron, cyromazine, and novaluron under laboratory conditions. field populations of ae. aegypti exhibited moderate resistance toward methoprene and low resistance toward pyriproxyfen, with resistance ratios of 12.7 and 1.4, respectively, but susceptibility to diflubenzuron, cyromazin ...201526336304
interspecific larval competition differentially impacts adult survival in dengue vectors.mosquitoes often experience intraspecific and interspecific competition among larvae attributable to high densities and nutrient limitation, especially container mosquitoes including aedes aegypti (l.) and aedes albopictus (skuse). density-dependent effects on larvae impact adult production and adult traits that influence transmission of arboviruses. to improve our understanding of the mechanisms by which density-dependence influences transmission and identify species-specific traits, we tested ...201526336301
essential oils of echinophora lamondiana (apiales: umbelliferae): a relationship between chemical profile and biting deterrence and larvicidal activity against mosquitoes (diptera: culicidae).the essential oils from the flower, leaf, and stem of echinophora lamondiana b.yildiz et z.bahcecioglu were analyzed by gas chromatography-flame ionization detection and gas chromatography-mass spectrometry. in total, 41, 37, and 44 compounds were identified, which accounted for 98.0, 99.1, and 97.0% of flower, leaf, and stem essential oils, respectively. the monoterpenic hydrocarbons were found to be high in all samples of the essential oils. the major components of essential oils from flower, ...201526336285
late-instar behavior of aedes aegypti (diptera: culicidae) larvae in different thermal and nutritive environments.the effects of temperature on ectotherm growth have been well documented. how temperature affects foraging behavior is less well explored, and has not been studied in larval mosquitoes. we hypothesized that temperature changes foraging behavior in the aquatic larval phase of the mosquito, aedes aegypti l. based on empirical results in other systems, we predicted that foraging effort would increase at higher temperatures in these insects. we tested this prediction over three temperature condition ...201526336228
larvicidal and biting deterrent activity of essential oils of curcuma longa, ar-turmerone, and curcuminoids against aedes aegypti and anopheles quadrimaculatus (culicidae: diptera).essential oils and extract of curcuma longa, ar-turmerone, and curcuminoids were evaluated for their larvicidal and deterrent activity against mosquitoes. ar-turmerone and curcuminoids constituted 36.9, 24.9 and 50.6% of rhizome oil, leaf oil, and rhizome extract, respectively. ar-turmerone was the major compound of the rhizome oil (36.9%) and leaf oil (24.9%). the ethanolic extract had 15.4% ar-turmerone with 6.6% bisdesmethoxycurcumin, 6.1% desmethoxycurcumin, and 22.6% curcumin. in in vitro s ...201526336212
potential effects of climate change on ecological interaction outcomes between two disease-vector mosquitoes: a mesocosm experimental study.the objective of this study was to experimentally assess the effects of different climate change scenarios on the outcomes of interactions between aedes aegypti (l.) and culex quinquefasciatus (say) (diptera: culicidae) larvae. the experimental design maintained a constant density of specimens while the proportion of the species in different experimental climate change scenarios varied. our results indicate that survival of the two species was not affected, but larval development and pupation ti ...201526336208
aedes aegypti (diptera: culicidae) in mauritania: first report on the presence of the arbovirus mosquito vector in nouakchott.aedes aegypti l. (diptera: culicidae) is a major vector of yellow fever, dengue, and chikungunya viruses throughout tropical and subtropical areas of the world. although the southernmost part of mauritania along the senegal river has long been recognized at risk of yellow fever transmission, aedes spp. mosquitoes had never been reported northwards in mauritania. here, we report the first observation of aedes aegypti aegypti (l.) and aedes (ochlerotatus) caspius (pallas, 1771) in the capital city ...201526335483
real-time pcr tests in dutch exotic mosquito surveys; implementation of aedes aegypti and aedes albopictus identification tests, and the development of tests for the identification of aedes atropalpus and aedes japonicus japonicus (diptera: culicidae).since 2009, the netherlands food and consumer product safety authority carries out surveys focusing on, amongst others, the presence of invasive mosquito species (ims). special attention is given to exotic container-breeding aedes species aedes aegypti (l.), aedes albopictus (skuse), aedes atropalpus (coquillett), and aedes japonicus japonicus (theobald). this study describes the implementation of real-time pcr tests described by hill et al. (2008) for the identification of ae. aegypti and ae. a ...201526334807
influence of time of assay on behavioral responses of laboratory and field populations aedes aegypti and culex quinquefasciatus (diptera: culicidae) to deet.knowledge on test conditions that may influence behavioral responses of mosquitoes is critical when excito-repellency tests are conducted. the objective of this study was to investigate the effect of test time differences on normal circadian activity and behavioral responses of field and colonized aedes aegypti (l.) (=stegomyia aegypti) and culex quinquefasciatus say to deet, one of the most common synthetic repellent active ingredients available. two field populations of ae. aegypti and cx. qui ...201426309311
protection from mosquito biting provided by permethrin-treated military fabrics.a study to evaluate the protection provided by permethrin-treated fabric following cold-water washing against biting by mosquitoes is reported. australian defense force (adf) disruptive pattern combat uniform (dpcu) shirt fabric and entire shirts were treated by dipping in a 0.6% emulsion (perigen defense, containing 500 g/liter permethrin), and commercial factory treatment in the united states (factory a) and europe (factory b). protection was recorded after 1, 3, 5, 10, 30, and 50 washes. the ...201426309310
inheritance of resistance to deltamethrin in aedes aegypti (diptera: culicidae) from cuba.the development of pyrethroid resistance in aedes aegypti (l) (diptera: culicidae) is a serious concern because major a. aegypti control programs are predominantly based on pyrethroid use during epidemic disease outbreaks. research about the genetic basis for pyrethroid resistance and how it is transmitted among mosquito populations is needed. the objective of this study was to determine how deltamethrin resistance is inherited in the cuban a. aegypti-resistant reference strain. here, a field po ...201426309309
comparative behavioral responses of pyrethroid-susceptible and -resistant aedes aegypti (diptera: culicidae) populations to citronella and eucalyptus oils.the objective of this study was to compare the behavioral responses (contact irritancy and noncontact spatial repellency) between susceptible and resistant populations of aedes aegypti (l.) (=stegomyia aegypti) to essential oils, citronella, and eucalyptus, eucalyptus globulus, extracts, using an excito-repellency test system. n, n-diethyl-meta-toluamide (deet) was used as the standard reference repellent. mosquitoes included two long-standing insecticide susceptible colonies (u.s. department of ...201426309305
[control of aedes aegypti breeding sites with the program recicla por tu bienestar in merida, mexico].to determine the importance of ae. aegypti breeding-sites in merida;to evaluate the impact of recicla por tu bienestar (rxb, a recycling program) on the reduction of breeding sites and the perception of participants.201726302122
eco-friendly control of malaria and arbovirus vectors using the mosquitofish gambusia affinis and ultra-low dosages of mimusops elengi-synthesized silver nanoparticles: towards an integrative approach?mosquito-borne diseases represent a deadly threat for millions of people worldwide. however, the use of synthetic insecticides to control culicidae may lead to high operational costs and adverse non-target effects. plant-borne compounds have been proposed for rapid extracellular synthesis of mosquitocidal nanoparticles. their impact against biological control agents of mosquito larval populations has been poorly studied. we synthesized silver nanoparticles (agnp) using the aqueous leaf extract o ...201526300364
further evidences for the mode of action of the larvicidal m-pentadecadienyl-phenol isolated from myracrodruon urundeuva seeds against aedes aegypti.nowadays, dengue fever is considered the most important arbovirosis worldwide and its control is still based upon combating the vector aedes aegypti. besides monitoring of mosquito populations resistant to conventional insecticides, the search for new environmentally safe insecticides and conduction of molecular studies focusing on the elucidation of mode of action and possible resistance mechanisms are considered the key for a sustainable management of the mosquito vector. thus, the present wor ...201526299195
widespread evidence for interspecific mating between aedes aegypti and aedes albopictus (diptera: culicidae) in nature.aedes aegypti and aedes albopictus, two important vectors of the dengue and chikungunya viruses to humans, often come in contact in their invasive ranges. in these circumstances, a number of factors are thought to influence their population dynamics, including resource competition among the larval stages, prevailing environmental conditions and reproductive interference in the form of satyrization. as the distribution and abundance of ae. aegypti and ae. albopictus have profound epidemiological ...201526296606
utilization of biodiesel by-products for mosquito control.the current paper has elaborated the efficient utilization of non-edible oil seed cakes (neoc), by-products of the bio-diesel extraction process to develop a herbal and novel mosquitocidal composition against the aedes aegypti larvae. the composition consisted of botanical active ingredients, inerts, burning agents and preservatives; where the botanical active ingredients were karanja (pongamia glabra) cake powder and jatropha (jatropha curcas) cake powder, products left after the extraction of ...201626296531
chitosan, carbon quantum dot, and silica nanoparticle mediated dsrna delivery for gene silencing in aedes aegypti: a comparative analysis.in spite of devastating impact of mosquito borne pathogens on humans, widespread resistance to chemical insecticides and environmental concerns from residual toxicity limit mosquito control strategies. we tested three nanoparticles, chitosan, carbon quantum dot (cqd), and silica complexed with dsrna, to target two mosquito genes (snf7 and src) for controlling aedes aegypti larvae. relative mrna levels were quantified using qrt-pcr to evaluate knockdown efficiency in nanoparticle-dsrna treated la ...201526291176
rapid biosynthesis of silver nanoparticles using crotalaria verrucosa leaves against the dengue vector aedes aegypti: what happens around? an analysis of dragonfly predatory behaviour after exposure at ultra-low doses.aedes aegypti is a primary vector of dengue, a mosquito-borne viral disease infecting 50-100 million people every year. here, we biosynthesised mosquitocidal silver nanoparticles (agnp) using the aqueous leaf extract of crotalaria verrucosa. the green synthesis of agnp was studied by uv-vis spectroscopy, sem, edx and ftir. c. verrucosa-synthesised agnps were toxic against a. aegypti larvae and pupae. lc50 of agnp ranged from 3.496 ppm (i instar larvae) to 17.700 ppm (pupae). furthermore, we eval ...201626284510
physiological and biochemical effects of botanical extract from piper nigrum linn (piperaceae) against the dengue vector aedes aegypti liston (diptera: culicidae).the leaves of piper nigrum l. (piperaceae) were evaluated for chemical constituents and mosquito larvicidal activity against the larvae of aedes aegypti. gc and gc-ms analyses revealed that the crude extracts contain 16 compounds. thymol (20.77%) and ç-elemene (10.42%) were identified as the major constituents followed by cyclohexene, 4-ethenyl-4-methyl-3-(1-methylethenyl)-1-(1 methylethyl)-, (3r-trans) (7.58%), 4,6-octadienoic acid, 2-acetyl-2-methyl-, ethyl ester (6.98), 2(3h)-furanone, 3,4-bi ...201526277727
green synthesis of silver nanoparticles from cassia roxburghii-a most potent power for mosquito control.mosquitoes transmit serious human diseases, causing millions of deaths every year. the use of synthetic insecticides to control vector mosquitoes has caused physiological resistance and adverse environmental effects in addition to high operational cost. insecticides of synthesized natural products for vector control have been a priority in this area. in the present study, silver nanoparticles (agnps) synthesized using cassia roxburghii plant leaf extract against anopheles stephensi, aedes aegypt ...201526276645
candidate biomarkers for mosquito age-grading identified by label-free quantitative analysis of protein expression in aedes albopictus females.we applied a "shotgun" approach based on nanoliquid chromatography-high resolution mass spectrometry associated to label free quantification (lfq) to identify proteins varying with age, independently from the physiological state, in aedes albopictus, a mosquito species which in the last decades invaded temperate regions in north america and europe, creating concerns for associated high nuisance and risk of arbovirus transmission. the combined "shotgun" and lfq approach was shown to be highly sui ...201526271156
diversity and abundance of mosquitoes (diptera:culicidae) in an urban park: larval habitats and temporal variation.urban parks are areas designated for human recreation but also serve as shelter and refuge for populations of several species of native fauna, both migratory and introduced. in brazil, the effect of annual climate variations on aedes aegypti and dengue epidemics in large cities like são paulo is well known, but little is known about how such variations can affect the diversity of mosquito vectors in urban parks and the risk of disease transmission by these vectors. this study investigates the in ...201526259817
effect of ultraviolet-a radiation on the production of leptolegnia chapmanii (saprolegniales: saprolegniaceae) zoospores on dead aedes aegypti (diptera: culicidae) larvae and their larvicidal activity.impact of uv-radiation in entomopathogens in aquatic environments remains little investigated. the present study reports on the effect of uv-a on the larvicidal activity of leptolegnia chapmanii zoospores in aedes aegypti; on the production of zoospores in larvae killed by the pathogen and then exposed to uv-a; and on the activity of these zoospores against healthy larvae. whereas the virulence of free zoospores in a. aegypti larvae was affected by a uv-a exposure time longer than 10min, product ...201526259676
mosquitocidal and oviposition repellent activities of the extracts of seaweed bryopsis pennata on aedes aegypti and aedes albopictus.the ever-increasing threat from infectious diseases and the development of insecticide resistance in mosquito populations drive the global search for new natural insecticides. the aims of this study were to evaluate the mosquitocidal activity of the extracts of seaweed bryopsis pennata against dengue vectors aedes aegypti and aedes albopictus, and determine the seaweed's toxic effect on brine shrimp nauplii (as a non-target organism). in addition, the chemical compositions of the active larvicid ...201526247928
effect of chloroxylon swietenia dc bark extracts against culex quinquefasciatus, aedes aegypti, and anopheles stephensi larvae.mosquitoes are the vector of more diseases and cause major health problems like malaria, dengue, chikungunya, and lymphatic filariasis. this article deals with the mosquito larvicidal activity of chloroxylon swietenia dc bark extracts against late third instar larvae of culex quinquefasciatus, aedes aegypti, and anopheles stephensi. methanolic crude extract of ch. swietenia bark was obtained by soxhlet apparatus and aqueous crude extract by cold percolation method. the range of concentrations of ...201526246308
forced egg retention and oviposition behavior of malaria, dengue and filariasis vectors to a topical repellent diethyl-phenylacetamide.egg retention and oviposition behavior of four species of mosquito vectors viz., anopheles stephensi, aedes aegypti, aedes albopictus, and culex quinquefasciatus to a topical insect repellent diethyl-phenylacetamide (depa) at 0.1-1000 mg/l was investigated under laboratory conditions. based on oviposition activity indices, depa demonstrated concentration dependent oviposition deterrent effect to a. stephensi (-0.18 to -0.97), a. aegypti (-0.18 to -0.91) and a. albopictus (-0.50 to -0.98) females ...201526245028
plant-borne ovicides in the fight against mosquito vectors of medical and veterinary importance: a systematic review.mosquitoes (diptera: culicidae) are a huge threat for millions of people worldwide, since they act as vectors for devastating parasites and pathogens. culicidae control is of crucial importance. mosquito eggs, larvae, and pupae are usually targeted using organophosphates, insect growth regulators, and microbial agents. indoor residual spraying and insecticide-treated bed nets are also employed. however, these chemicals have negative effects on human health and the environment, and induce resista ...201526239801
[neonatal dengue. presentation of clinical cases].dengue is an infectious disease caused by a flavivirus, with four serotypes, transmitted by the mosquito aedes aegypti. in mexico it is a public health problem, especially in the region of central and southeast of the country. the disease can be asymptomatic or present serious forms and even death. it is confirmed by detection of the ns1 antigen; igm antibodies, polymerase chain reaction and virus isolation. the vertical transmission to de newborn has been little studied. 7 cases in neonates fro ...201526233977
host-feeding pattern of aedes aegypti and aedes albopictus (diptera: culicidae) in heterogeneous landscapes of south andaman, andaman and nicobar islands, india.mosquito foraging behavior is a determinant of host-vector contact and has an impact on the risk of arboviral epidemics. therefore, blood-feeding patterns is a useful tool for assessing the role in pathogen transmission by vector mosquitoes. competent vectors of dengue and chikungunya viz. aedes aegypti and aedes albopictus are widely prevalent in the andaman and nicobar archipelago. considering the vector potential, medical importance of both these mosquito species and lack of information on ho ...201526220560
tree holes as larval habitats for aedes aegypti in urban, suburban and forest habitats in a dengue affected area.aedes aegypti (l.) (diptera: culicidae), the main vector of dengue and urban yellow fever in the world, is highly adapted to the human environment. artificial containers are the most common larval habitat for the species, but it may develop in tree holes and other phytotelmata. this study assessed whether tree holes in san ramón de la nueva orán, a city located in subtropical montane moist forest where dengue outbreaks occur, are relevant as larval habitat for ae. aegypti and if the species may ...201526193903
characterization and biotoxicity of hypnea musciformis-synthesized silver nanoparticles as potential eco-friendly control tool against aedes aegypti and plutella xylostella.two of the most important challenges facing humanity in the 21st century comprise food production and disease control. eco-friendly control tools against mosquito vectors and agricultural pests are urgently needed. insecticidal products of marine origin have a huge potential to control these pests. in this research, we reported a single-step method to synthesize silver nanoparticles (agnp) using the aqueous leaf extract of the seaweed hypnea musciformis, a cheap, nontoxic and eco-friendly materi ...201526184431
evaluation of three commercial backpack sprayers with aqualuer® 20-20 against caged adult aedes aegypti.three commercially available backpack sprayers were evaluated with aqualuer® 20-20 (20.6% permethrin, active ingredient; 20.6% piperonyl butoxide, technical) against caged adult aedes aegypti in semifield trials in northeastern florida. two battery-powered sprayers, birchmeier and hudson, were compared with the standard hand-pump solo 425 sprayer, which is currently used in pest management operations. physical characteristics, droplet analysis, and overall ease of use were documented. multiple d ...201526181698
a trypsin inhibitor from clitoria fairchildiana cotyledons is active against digestive enzymes of aedes aegypti larvae.aedes aegypti, the principal mosquito vector of yellow fever, dengue fever and chikungunya fever virus-transmitted diseases, is an insect closely associated with humans and their housing habitats. as there is no commercially available vaccine, prevention is the most suggested form of avoiding disease spreading and a number of studies are being developed in order to give support to vector control operations. the present study reports on the identification of a trypsin inhibitor isolated from coty ...201526156641
evaluation of silver nanoparticles toxicity of arachis hypogaea peel extracts and its larvicidal activity against malaria and dengue vectors.silver nanoparticles (agnps) were successfully synthesised from aqueous silver nitrate using the extracts of arachis hypogaea peels. the synthesised snps were characterized by fourier transform-infrared spectroscopy analysis, x-ray diffraction, transmission electron microscopy analysis and high-resonance scanning electron microscopy, and energy dispersive x-ray spectroscopy. agnps were well defined and measured 20 to 50 nm in size. the nanoparticles were crystallized with a face-centered cubic s ...201526154036
[microgeographic and temporal genetic changes of aedes aegypti from medellín, colombia].aedes aegypti populations may experience changes in abundance and genetic diversity in addition to changes in their evolutionary capability to respond to vector control. the knowledge on the changes in genetic variation on a spatio-temporal scale improves the epidemiological understanding of dengue and supports the appropriate and timely design of vector control strategies.201526148034
[insecticide susceptibility evaluation in aedes aegypti populations of caldas, colombia, in 2007 and 2011].continuous use of insecticides for the control of dengue transmission may lead to decreased susceptibility levels in mosquito vector populations. timely monitoring is necessary to ensure detection of any potential resistance problems.201526148033
insecticidal potential of ocimum canum plant extracts against anopheles stephensi, aedes aegypti and culex quinquefasciatus larval and adult mosquitoes (diptera: culicidae).mosquitoes have developed resistance to various synthetic insecticides, making their control increasingly difficult. insecticides of botanical origin may serve as suitable natural control. this study evaluates the toxic potential of ocimum canum (sims) leaf extract and powder against anopheles stephensi (liston), aedes aegypti (lin) and culex quinquefasciatus (say) larval and adult mosquitoes. larval mortality was observed after 24 h recovery period and adult smoke toxicity observed for 40 min d ...201626135241
an environmentally safe larvicide against aedes aegypti based on in situ gelling nanostructured surfactant systems containing an essential oil.liquid crystalline precursors, which are in situ gelling nanostructured surfactant systems, can undergo phase transition in aqueous solution and become more structured aggregates, controlling release of larvicides and acting as biotechnology alternatives for dengue control. such systems can contain bioactive substances as citrus sinensis essential oil (cseo) which exhibits biological activity against aedes aegypti (ae. aegypti) larvae.201526125515
susceptibility status of aedes aegypti (l.) (diptera: culicidae) to temephos from three districts of tamil nadu, india.dengue is the most rapidly expanding arboviral disease in india. aedes aegypti is the primary vector of dengue fever. chemical insecticides have long been used in the vector control programmes along with other control measures. however, continuous use of insecticides targeting ae. aegypti may lead to development of insecticide resistance. though resistance in ae. aegypti has been reported, the mutation in ace-1 gene associated with temephos resistance is not reported in natural populations. the ...201526119549
boric acid ovicidal trap for the management of aedes species.the use of low concentrations of boric acid as a potential and effective control agent for the eggs and immature stages of aedes aegypti l. and aedes albopictus skuse (diptera: culicidae) is found to be safe and effective as compared to synthetic chemical insecticides. the study aims to determine the ovicidal concentration of boric acid, its effective concentration for oviposition attraction and the larval mortality concentration for ae. aegypti and ae. albopictus.201526119547
the epidemiology of dengue fever in saudi arabia: a systematic review.dengue fever (df) is the most serious mosquito-borne viral disease worldwide. df is an acute febrile illness caused by aedes aegypti and aedes albopictus, which are endemic in certain cities of saudi arabia, such as jeddah and makkah (mecca). an online literature search was conducted using relevant keywords to retrieve df studies conducted in saudi arabia. forty-five articles were identified initially. after screening for exclusion and retrieving full texts, a total of 10 articles were used for ...201626106040
proteomic changes occurring in the malaria mosquitoes anopheles gambiae and anopheles stephensi during aging.the age of mosquitoes is a crucial determinant of their ability to transmit pathogens and their resistance to insecticides. we investigated changes to the abundance of proteins found in heads and thoraces of the malaria mosquitoes anopheles gambiae and anopheles stephensi as they aged. protein expression changes were assessed using two-dimensional difference gel electrophoresis and the identity of differentially expressed proteins was determined by using either matrix-assisted laser desorption i ...201526100052
characterization and bioassay for larvicidal activity of anacardium occidentale (cashew) shell waste fractions against dengue vector aedes aegypti.recent studies regarding the harmful effects of synthetic larvicides initiated the need to investigate for unconventional measures that are environmentally safe and target-specific against aedes aegypti larvae. thus, the main objectives of the study are to evaluate the larvicidal toxicity of the solvent fractions of anacardium occidentale shell wastes against the third and fourth instar larvae of a. aegypti and to compare the results with the commercial larvicide product. the shell wastes were e ...201526099240
surveillance of adult aedes mosquitoes in selangor, malaysia.to determine the effectiveness of using sticky traps and the ns1 dengue antigen kit for the surveillance of aedes mosquitoes for dengue control.201526094839
predation by asian bullfrog tadpoles, hoplobatrachus tigerinus, against the dengue vector, aedes aegypti, in an aquatic environment treated with mosquitocidal nanoparticles.aedes aegypti is a primary vector of dengue and chikungunya. the use of synthetic insecticides to control aedes populations often leads to high operational costs and adverse non-target effects. botanical extracts have been proposed for rapid extracellular synthesis of mosquitocidal nanoparticles, but their impact against predators of mosquito larvae has not been well studied. we propose a single-step method for the biosynthesis of silver nanoparticles (agnp) using the extract of artemisia vulgar ...201526091763
phytochemical profile and larvicidal properties of seed essential oil from nigella sativa l. (ranunculaceae), against aedes aegypti, anopheles stephensi, and culex quinquefasciatus (diptera: culicidae).the present study deals with investigation of larvicidal activity and their chemical constituents of the essential oil from the seeds of nigella sativa l. (ranunculaceae). totally, 18 chemical compounds were identified by gc and gc-ms analysis. thymol (19.13 %) and α-phellandrene (14.9 %) were identified as major chemical components followed by camphor (12.14 %), borneol (11.31 %), and carvacrol (8.65 %). the larval mortality was observed after 12 and 24 h of exposure period. the results reveale ...201526091760
thiosemicarbazones as aedes aegypti larvicidal.a set of aryl- and phenoxymethyl-(thio)semicarbazones were synthetized, characterized and biologically evaluated against the larvae of aedes aegypti (a. aegypti), the vector responsible for diseases like dengue and yellow fever. (q)sar studies were useful for predicting the activities of the compounds not included to create the qsar model as well as to predict the features of a new compound with improved activity. docking studies corroborated experimental evidence of aescp-2 as a potential targe ...201526087027
a sodium channel variant in aedes aegypti as a candidate pathogen sensor for viral-associated molecular patterns.recent work demonstrated that a splice variant of a human macrophage voltage-gated sodium channel expressed on endosomes acts as an intracellular sensor for dsrna, a viral-associated molecular pattern. here our goal was to identify a candidate gene in a clinically relevant invertebrate model with related cellular and pattern recognition properties. the para gene in drosophila and other insects encodes voltage-gated sodium channels with similar electrophysiological properties to those found in ve ...201526086103
localization and role of inward rectifier k(+) channels in malpighian tubules of the yellow fever mosquito aedes aegypti.malpighian tubules of adult female yellow fever mosquitoes aedes aegypti express three inward rectifier k(+) (kir) channel subunits: aekir1, aekir2b and aekir3. here we 1) elucidate the cellular and membrane localization of these three channels in the malpighian tubules, and 2) characterize the effects of small molecule inhibitors of aekir1 and aekir2b channels (vu compounds) on the transepithelial secretion of fluid and electrolytes and the electrophysiology of isolated malpighian tubules. usin ...201526079629
proteomic analysis of immunogenic proteins from salivary glands of aedes aegypti.humans develop anti-salivary proteins after arthropod bites or exposure to insect salivary proteins. this reaction indicates that vector bites have a positive effect on the host immune response, which can be used as epidemiological markers of exposure to the vector. our previous study identified two immunogenic proteins with molecular weights of 31 kda and 56 kda from salivary gland extract (sge) of aedes aegypti that cross-reacted with serum samples from dengue hemorrhagic fever (dhf) patients ...201526054892
the effect of photoperiod on life history and blood-feeding activity in aedes albopictus and aedes aegypti (diptera: culicidae).several studies have examined how climatic variables such as temperature and precipitation may affect life history traits in mosquitoes that are important to disease transmission. despite its importance as a seasonal cue in nature, studies investigating the influence of photoperiod on such traits are relatively few. this study aims to investigate how photoperiod alters life history traits, survival, and blood-feeding activity in aedes albopictus (skuse) and aedes aegypti (linnaeus). we performed ...201526047197
lethal ovitrap deployment for aedes aegypti control: potential implications for non-target organisms.in australia, dengue control combines source reduction with lethal ovitraps to reduce aedes aegypti populations during outbreaks. lethal ovitraps are considered a sustainable and environmentally friendly method of controlling container-inhabiting mosquitoes, however, to-date, this claim has not been quantified. this study assesses the potential impact of lethal ovitraps on non-target organisms when used to control ae. aegypti in tropical australia. for retention of specimens, we substituted stan ...201526047194
volatile semiochemical-conditioned attraction of the male yellow fever mosquito, aedes aegypti, to human hosts.we investigated the olfactory responses of male mosquitoes to kairomones of vertebrate hosts in a dual-port olfactometer. the behavioral responses of unmated and mated male and female mosquitoes from one to ten days old to human odors were compared to the odors of different human hosts. to evaluate the relationship between the age of male mosquitoes and their responses, we performed experiments with males at different ages. unmated ae. aegypti males, one to two days old, did not fly upwind to hu ...201526047178
effects of α,β-unsaturated lactones on larval survival and gut trypsin as well as oviposition response of aedes aegypti.lactones are organic cyclic esters that have been described as larvicides against aedes aegypti and as components of oviposition pheromone of culex quinquefasciatus. this work describes the effect of six α,β-unsaturated lactones (5a-5f) on survival of a. aegypti fourth instar larvae (l4). it is also reported the effects of the lactones on l4 gut trypsin activity and oviposition behavior of a. aegypti females. five lactones were able to kill l4 being the lactones 5a (lc50 of 39.05 ppm), 5e (lc50 ...201526044355
spatial models for prediction and early warning of aedes aegypti proliferation from data on climate change and variability in cuba.climate variability, the primary expression of climate change, is one of the most important environmental problems affecting human health, particularly vector-borne diseases. despite research efforts worldwide, there are few studies addressing the use of information on climate variability for prevention and early warning of vector-borne infectious diseases.201526027583
[omics of vector mosquitoes: a big data platform for vector biology and vector-borne diseases].recently the studies on mosquito genomics, transcriptomics and small rnaomics developed rapidly with the novel biotechnologies of the next generation sequencing techniques. the genome sequences of several important vector mosquitoes including anopheles gambiae, culex quinquefasciatus, and aedes aegypti have been published. the genome sizes vary among the different species of mosquitoes and are consistent with the number of the repeat regions. the released genome sequences facilitate gene cloning ...201526018253
annona muricata leaf extract-mediated silver nanoparticles synthesis and its larvicidal potential against dengue, malaria and filariasis vector.mosquitoes transmit several diseases which cause millions of deaths every year. the use of synthetic insecticides to control mosquitoes caused diverse effects to the environment, mammals, and high manufacturing cost. the present study was aimed to test the larvicidal activity of green synthesized silver nanoparticles using annona muricata plant leaf extract against third instar larvae of three medically important mosquitoes, i.e., aedes aegypti, anopheles stephensi, and culex quinquefasciatus. t ...201526002825
unique biochemical and molecular biological mechanism of synergistic actions of formamidine compounds on selected pyrethroid and neonicotinoid insecticides on the fourth instar larvae of aedes aegypti (diptera: culicidae).we recently reported that formamidine pesticides such as amitraz and chlordimeform effectively synergize toxic actions of certain pyrethroid and neonicotinoid insecticides in some insect species on the 4th instar larvae of aedes aegypti. here we studied the biochemical basis of the synergistic actions of the formamidines in amplifying the toxicity of neonicotinoids and pyrethroids such as dinotefuran and thiamethoxam, as well as deltamethrin-fenvalerate type of pyrethroids. we tested the hypothe ...201525987221
synergistic action of octopamine receptor agonists on the activity of selected novel insecticides for control of dengue vector aedes aegypti (diptera: culicidae) mosquito.studying insecticide resistance in mosquitoes has attracted the attention of many scientists to elucidate the pathways of resistance development and to design novel strategies in order to prevent or minimize the spread and evolution of resistance. here, we tested the synergistic action of piperonyl butoxide (pbo) and two octopamine receptor (or) agonists, amitraz (amz) and chlordimeform (cdm) on selected novel insecticides to increase their lethal action on the fourth instar larvae of aedes aegy ...201525987220
experience- and age-mediated oviposition behaviour in the yellow fever mosquito stegomyia aegypti (=aedes aegypti).in repeated behaviours such as those of feeding and reproduction, past experiences can inform future behaviour. by altering their behaviour in response to environmental stimuli, insects in highly variable landscapes can tailor their behaviour to their particular environment. in particular, female mosquitoes may benefit from plasticity in their choice of egg-laying site as these sites are often temporally variable and clustered. the opportunity to adapt egg-laying behaviour to past experience als ...201525982411
larvicidal activity against aedes aegypti of foeniculum vulgare essential oils from portugal and cape verde.dengue is a potentially fatal mosquito-borne infection with 50 million cases per year and 2.5 billion people vulnerable to the disease. this major public health problem has recurrent epidemics in latin america and occurred recently in cape verde and madeira island. the lack of anti-viral treatment or vaccine makes the control of mosquito vectors a high option to prevent virus transmission. essential oil (eo) constituents can affect insect's behaviour, being potentially effective in pest control. ...201525973508
imidacloprid impairs the post-embryonic development of the midgut in the yellow fever mosquito stegomyia aegypti (=aedes aegypti).the mosquito stegomyia aegypti (=aedes aegypti) (diptera: culicidae) is a vector for the dengue and yellow fever viruses. as blood digestion occurs in the midgut, this organ constitutes the route of entry of many pathogens. the effects of the insecticide imidacloprid on the survival of st. aegypti were investigated and the sub-lethal effects of the insecticide on midgut development were determined. third instar larvae were exposed to different concentrations of imidacloprid (0.15, 1.5, 3.0, 6.0 ...201525968596
oxime derivatives with larvicidal activity against aedes aegypti l.oximes containing secondary metabolites constitute an important group of bioactive compounds and have been described and frequently updated in the literature due to their pharmacological properties. thus, the aim of this study was to evaluate the larvicidal activity of a series of fourteen structurally related [1,4]-benzoquinone mono-oximes on third-instar aedes aegypti larvae and to investigate structure-activity relationships (sar) of these compounds. results of larvicidal assay revealed that ...201525956398
involvement of metabolic resistance and f1534c kdr mutation in the pyrethroid resistance mechanisms of aedes aegypti in india.pesticide resistance poses a serious problem for worldwide mosquito control programs. resistance to insecticides can be caused by an increased metabolic detoxification of the insecticide and/or by target site insensitivity. in the present study, we estimated the tolerance of indian aedes aegypti populations using adult bioassays that revealed high resistance levels of the field populations to permethrin (rr-6, 5.8 and 5.1 folds) compared to our susceptible population. enzymatic assays revealed i ...201525944353
susceptibility to temephos, permethrin and deltamethrin of aedes aegypti (diptera: culicidae) from muang district, phitsanulok province, thailand.to investigate the susceptibility to temephos, permethrin and deltamethrin of aedes aegypti (ae. aegypti), collected from areas with high incidence of dengue hemorrhagic fever cases in phitsanulok province, thailand.201525901918
frizzled 2 is a key component in the regulation of tor signaling-mediated egg production in the mosquito aedes aegypti.the wnt signaling pathway was first discovered as a key event in embryonic development and cell polarity in drosophila. recently, several reports have shown that wnt stimulates translation and cell growth by activating the mtor pathway in mammals. previous studies have demonstrated that the target of rapamycin (tor) pathway plays an important role in mosquito vitellogenesis. however, the interactions between these two pathways are poorly understood in the mosquito. in this study, we hypothesized ...201525890109
structure-activity relationship (sar) modelling of mosquito larvicides.an attempt was made to derive structure-activity models allowing the prediction of the larvicidal activity of structurally diverse chemicals against mosquitoes. a database of 188 chemicals with their activity on aedes aegypti larvae was constituted from analysis of original publications. the activity values were expressed in log 1/ic50 (concentration required to produce 50% inhibition of larval development, mmol). all the chemicals were encoded by means of codessa and autocorrelation descriptors ...201525864415
Displaying items 10901 - 11000 of 14974