| microbiological effects of periodontal therapy plus azithromycin in patients with diabetes: results from a randomized clinical trial. | current evidence suggests that periodontal infection may aggravate diabetes control. the aim of this study was to determine the changes in the frequency with which porphyromonas gingivalis, tannerella forsythia, treponema denticola and aggregatibacter actinomycetemcomitans were detected in patients with diabetes with the use of non-surgical therapy plus azithromycin in a randomized clinical trial. one hundred and five (105) patients with diabetes and chronic periodontitis were randomly assigned ... | 2014 | 25523961 |
| clinical, microbial, and immune responses observed in patients with diabetes after treatment for gingivitis: a three-month randomized clinical trial. | although patients with diabetes are frequently affected by periodontitis, only a few investigations have focused on gingivitis in this at-risk population. this randomized placebo-controlled clinical trial compared the response to a gingivitis treatment protocol that combined mechanical procedures and daily use of an essential oil (eo) mouthrinse between patients with and without diabetes. | 2015 | 25494658 |
| adjunctive moxifloxacin in the treatment of generalized aggressive periodontitis patients: clinical and microbiological results of a randomized, triple-blind and placebo-controlled clinical trial. | the aim of the present study was to evaluate the clinical and microbiological efficacy of moxifloxacin (mox) in one-stage scaling and root planing (srp) in treating generalized aggressive periodontitis (gagp). | 2015 | 25469723 |
| detection of periodontal pathogens in the patients with aortic aneurysm. | the occurrence and development of aortic aneurysm (aa) are associated with infection. some researchers have detected the dna of periodontal pathogens in aa samples in certain populations. however, it has not been done in chinese population. the objective of this study was to evaluate the prevalence of periodontal pathogens in oral tissue samples and aneurysm samples of aa patients. | 2014 | 25430459 |
| prevalence of six periodontal pathogens in subgingival samples of italian patients with chronic periodontitis. | the aim of this study was to investigate the subgingival prevalence of six periodontal pathogens in 352 italian patients with chronic periodontitis. possible correlations with clinical parameters, age, gender and smoking status were also investigated. at first visit a pooled subgingival plaque sample was obtained for each subject by using the paper-point method. the samples were processed and analysed according to a commercially available quantitative real time polymerase chain reaction assay (m ... | 2014 | 25387289 |
| evaluation of adjunctive systemic doxycycline with non-surgical periodontal therapy within type 2 diabetic patients. | to evaluate the effects of systemic doxycycline on clinical and microbiological parameters of diabetic subjects with chronic periodontitis. | 2014 | 25316464 |
| polymerase chain reaction as a prospect for the early diagnosis and prediction of periodontal diseases in adolescents. | this study was to determine the markers representative of pathogenic periodontal microflora [prevotella intermedia (p.i), tannerella forsythia (t.f) [bacteroides forsythus], treponema denticola (t.d), actinobacillus actinomycetemcomitans (a.a), porphyromonas gingivalis (p.g)] in the dental plaque of adolescents with various degrees of severity of periodontium inflammation. | 2015 | 25266040 |
| antibodies to periodontal pathogens are associated with coronary plaque remodeling but not with vulnerability or burden. | previous studies have suggested positive associations between periodontal infection and cardiovascular disease. we aimed to investigate the associations of circulating antibodies against periodontal pathogens with 1-year cardiovascular outcome, as well as the extent of coronary atherosclerosis, plaque vulnerability and lesion remodeling on intravascular ultrasound (ivus) imaging. | 2014 | 25233105 |
| real-time pcr quantification of six periodontal pathogens in saliva samples from healthy young adults. | the use of saliva as a diagnostic fluid for the evaluation of periodontal health has gained attention recently. most published real-time pcr assays focused on quantification of bacteria in subgingival plaque, not in saliva. the aims of this study were to develop a real-time pcr assay for quantification of six periodontal pathogens in saliva and to establish a relationship between the amount of dna (fg) and colony-forming unit (cfu). | 2015 | 25217278 |
| igg sera levels against a subset of periodontopathogens and severity of disease in aggressive periodontitis patients: a cross-sectional study of selected pocket sites. | to evaluate the association among serum immunoglobulin g (igg) responses to aggregatibacter actinomycetemcomitans (aa) serotypes a, b and c, porphyromonas gingivalis (pg), tannerella forsythia (tf) and clinical parameters in aggressive periodontitis (ap) subjects. associations between periodontal pathogens and clinical and immunological parameters were also evaluated. | 2014 | 25070874 |
| periodontopathogens and human β-defensin-2 expression in gingival crevicular fluid from patients with periodontal disease in guangxi, china. | periodontal diseases are often induced by periodontopathogens, which are always exposed to certain innate immune factors in gingival crevicular fluid, including human β-defensin-2 (hbd-2). this study aims to investigate the relationship among periodontopathogens, clinical parameters and hbd-2 expression. | 2015 | 25065393 |
| effect of repeated adjunctive antimicrobial photodynamic therapy on subgingival periodontal pathogens in the treatment of chronic periodontitis. | the aim of this study was to compare the effect of subgingival ultrasonic scaling followed by repeated (three times) antimicrobial photodynamic therapy (pdt), ultrasonic scaling alone (us), and scaling and root planing with hand instruments (srp) for initial periodontal treatment. twenty-seven non-smoking systemically healthy chronic periodontitis patients were included. residual pockets ≥4 mm deep and bleeding on probing were debrided either with srp, us alone, or us followed by a single episod ... | 2015 | 25056413 |
| antibacterial activities of extracts from ugandan medicinal plants used for oral care. | medicinal plants are widely used for treatment of oral/dental diseases in uganda. | 2014 | 24945400 |
| periodontal pathogens in atheromatous plaque. | there has been increasing attention paid in recent years to the possibility that oral bacterial infection, particularly periodontal disease may influence the initiation and or progression of systemic diseases. these studies confirm the observation that heart disease is the most commonly found systemic condition in patients with periodontal disease. moreover, the literature has also highlighted substantial evidence indicating the presence of gram-negative periodontal pathogens in atheromatous pla ... | 2014 | 24943760 |
| internal bacterial colonization of implants: association with peri-implant bone loss. | the aim of the present longitudinal study was to investigate bacterial colonization of the internal implant cavity and to evaluate a possible association with peri-implant bone loss. | 2015 | 24861845 |
| clinical and microbiological characterization of localized aggressive periodontitis: a cohort study. | localized aggressive periodontitis (lagp) is an infectious periodontal disease which generally affects young people. recent data suggest the involvement of different bacterial species in different populations. the causative bacterial species in israel has never been identified despite a high prevalence of lagp in this population. the objectives of this study were to characterize the bacterial microbiota of periodontal pockets within an israeli lagp population who were also clinically assessed. | 2014 | 24861390 |
| evaluation of periodontal pathogens of the mandibular third molar pericoronitis by using real time pcr. | the aim of this study was to investigate the mandibular third molar pericoronitis flora by using real-time polymerase chain reaction (pcr). | 2014 | 24835305 |
| relationship between expression of human gingival beta-defensins and levels of periodontopathogens in subgingival plaque. | human beta-defensins (hbds) are a group of antimicrobial peptides important in epithelial innate immunity, and their differential expression is associated with periodontal diseases. the aim of this study was to explore relationships among hbds, total subgingival bacteria and periodontopathogens in healthy subjects and in patients with chronic periodontitis. | 2015 | 24814979 |
| detection and quantification of periodontal pathogens in smokers and never-smokers with chronic periodontitis by real-time polymerase chain reaction. | the purpose of the present investigation is to compare the presence and number of periodontal pathogens in the subgingival microbiota of smokers versus never-smokers with chronic periodontitis and matched probing depths (pds) using real-time polymerase chain reaction (rt-pcr). | 2014 | 24794687 |
| genetic characteristics and pathogenic mechanisms of periodontal pathogens. | periodontal disease is caused by a group of bacteria that utilize a variety of strategies and molecular mechanisms to evade or overcome host defenses. recent research has uncovered new evidence illuminating interesting aspects of the virulence of these bacteria and their genomic variability. this paper summarizes some of the strategies utilized by the major species - aggregatibacter actinomycetemcomitans, tannerella forsythia, treponema denticola, and porphyromonas gingivalis - implicated in the ... | 2014 | 24736700 |
| assessment of periodontal and opportunistic flora in patients with peri-implantitis. | to assess the presence of periodontal and opportunistic organisms in patients with peri-implantitis. | 2015 | 24720498 |
| periodontal pathogens and associated factors in aggressive periodontitis: results 5-17 years after active periodontal therapy. | to assess the association between presence of periodontal pathogens and recurrence of disease in patients with aggressive periodontitis (agp) after active periodontal therapy (apt) and further influencing factors. | 2014 | 24708362 |
| [clinical and microbiological effects of the initial periodontal therapy]. | periodontitis is a destructive inflammatory disease of the tooth-supporting tissues, primarily caused by gram-negative microorganisms. thus, the primary objective of cause-related initial periodontal therapy is disruption and removal of the subgingival biofilm. | 2014 | 24684025 |
| microbiological assessment of the implant-abutment interface in different connections: cross-sectional study after 5 years of functional loading. | to evaluate the bacterial microflora present inside the implant connection and in the peri-implant sulcus fluid of healthy implants, and to analyze the relationships between these harboring sites for four different implant systems after at least 5 years of functional loading. | 2015 | 24665919 |
| clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial. | the aim of the present study was to evaluate the clinical and microbiological effect of systemic levofloxacin (lfx) as an adjunct to scaling and root planing (srp) in patients with chronic periodontitis (cp). | 2015 | 24574052 |
| [dissertations 25 years after date 37. susceptibility to periodontal diseases]. | in the eighties of the former century it was observed that individuals had different modes of development of periodontitis, largely for unknown reasons. it was assumed that periodontal disease developed as a result of the presence of virulent micro-organisms in combination with an inadequate host response. the concept of this (im)balance in host parasite interactions developed further, in part because of new research techniques. with respect to oral bacteria it was shown that periodontal pathoge ... | 2013 | 24555252 |
| subgingival plaque sampling after combined mechanical and antibiotic nonsurgical periodontal therapy. | this study aimed to make a comparison of two sampling strategies of subgingival plaque after combined mechanical-antibiotic periodontal therapy. | 2015 | 24554003 |
| quantification of periodontal pathogens in vascular, blood, and subgingival samples from patients with peripheral arterial disease or abdominal aortic aneurysms. | the aim of this investigation is to quantify periodontal pathogens (aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, campylobacter rectus, and tannerella forsythia) in vascular, blood, and subgingival samples. as a secondary objective, two molecular bacterial identification methods (nested polymerase chain reaction [pcr] and quantitative pcr [qpcr]) are compared. | 2014 | 24502612 |
| in vivo effectiveness of silicone gel sheets as barriers at the inner microgap between a prosthetic abutment and an external-hexagon implant platform. | bacterial penetration and colonization of the microgap at the implant-abutment interface have been reported in several studies. the aim of this study was to evaluate the effectiveness of placing a silicone membrane between the abutment and the implant platform in an attempt to seal the interface. | 2014 | 24451862 |
| periodontal bacteria in the genital tract: are they related to adverse pregnancy outcome? | one of the most important factors implicated in preterm birth (ptb) is acute genitourinary tract infection. the bacteria causing chronic periodontal inflammation include gram-negative rods and anaerobes similar to those found in women with bacterial vaginosis. the aim of this prospective study is to investigate the relationship between oral and vaginal microflora and preterm low birth weight. real-time polymerase chain reaction was used to detect both the presence and level of six periodontitis- ... | 2017 | 24355228 |
| biology and pathogenesis of cytomegalovirus in periodontal disease. | human periodontitis is associated with a wide range of bacteria and viruses and with complex innate and adaptive immune responses. porphyromonas gingivalis, tannerella forsythia, aggregatibacter actinomycetemcomitans, treponema denticola, cytomegalovirus and other herpesviruses are major suspected pathogens of periodontitis, and a combined herpesvirus-bacterial periodontal infection can potentially explain major clinical features of the disease. cytomegalovirus infects periodontal macrophages an ... | 2014 | 24320955 |
| detection of putative periodontopathic bacteria in type 1 diabetic and healthy children: a comparative study. | the aim of this study was to compare and assess the risk of periodontitis due to the presence of four putative periodontopathic bacteria (porphyromonas gingivalis, treponema denticola, tannerella forsythia, and aggregatibacter actinomycetemcomitans) in type 1 diabetic and healthy children. | 2013 | 24025882 |
| molecular microbiological evaluation of subgingival biofilm sampling by paper point and curette. | the present clinical study aimed to investigate if there are differences in microbiological outcomes dependent on the subgingival biofilm collection method. subgingival biofilm samples were collected from the four deepest pockets (>5 mm) of 17 patients with aggressive periodontitis (agp) and 33 patients with chronic periodontitis (cp), first by paper point and thereafter by curette. samples obtained with the same method were pooled together from each patient and forwarded for molecular microbiol ... | 2014 | 23879704 |
| occurrence of red complex microorganisms and aggregatibacter actinomycetemcomitans in patients with diabetes. | the aim of the present study was to analyze the occurrence of porphyromonas gingivalis (p. gingivalis), tannerella forsythia (t. forsythia), treponema denticola (t. denticola), and aggregatibacter actinomycetemcomitans (a. actinomycetemcomitans) in patients with diabetes. | 2015 | 23857867 |
| characterization of periodontal biofilm in down syndrome patients: a comparative study. | the aim of this study was to characterize the main periodontal bacterial species in down syndrome (ds) patients with and without periodontitis. | 2013 | 23855174 |
| quantification of key periodontal pathogens in insulin-dependent type 2 diabetic and non-diabetic patients with generalized chronic periodontitis. | periodontitis is a common problem in patients with diabetes mellitus (dm), however, differences in the putative periodontal pathogens in subjects with dm compared to non-dm subjects are still inconclusive. the red complex, which includes porphyromonas gingivalis, treponema denticola, and tannerella forsythia, encompasses the most important pathogens in adult periodontal disease. the aim of the present study was to compare cell numbers of p. gingivalis, t. denticola, t. forsythia and aggregatibac ... | 2013 | 23827459 |
| clinical and microbiologic effect of nonsurgical periodontal therapy on patients with chronic or aggressive periodontitis. | to evaluate the changes in the clinical parameters, and the prevalence and quantities of three major periodontopathic bacteria, namely porphyromonas gingivalis, aggregatibacter actinomycetemcomitans, and tannerella forsythia, in subgingival plaque collected from patients with generalized chronic periodontitis (gcp) or generalized aggressive periodontitis (gagp) in response to nonsurgical periodontal therapy. | 2013 | 23757461 |
| rheumatoid arthritis is an autoimmune disease caused by periodontal pathogens. | a statistically significant association between periodontal disease (pd) and systemic diseases has been identified. rheumatoid arthritis (ra), which is a chronic inflammatory joint disease, exhibits similar characteristics and pathogenesis to pd. the association between ra and pd has been investigated, and numerous publications on this subject exist. approximately 20 bacterial species have been identified as periodontal pathogens, and these organisms are linked to various types of pd. the most a ... | 2013 | 23737674 |
| porphyromonas gingivalis, treponema denticola and toll-like receptor 2 are associated with hypertensive disorders in placental tissue: a case-control study. | to explore the associations between the presence of periodontal pathogens and the expression of toll-like receptors (tlr-2 and tlr-4) in the placental tissue of patients with hypertensive disorders compared to the placentas of healthy normotensive patients. | 2013 | 23711357 |
| a randomized controlled clinical trial on the clinical and microbiological efficacy of systemic satranidazole in the treatment of chronic periodontitis. | the present clinical trial was designed to investigate the effectiveness of systemic satranidazole (sz) as an adjunct to scaling and root planing (srp) in the treatment of chronic periodontitis. | 2013 | 23705535 |
| periodontopathogen and epstein-barr virus-associated periapical periodontitis may be the source of retrograde infectious peri-implantitis. | herpesviral-bacterial synergism may play a role in periodontitis and peri-implantitis etiopathogenesis. periapical periodontitis (pp) lesions can predict future apical peri-implantitis complications. | 2015 | 23675952 |
| soluble triggering receptor expressed on myeloid cells 1 (strem-1) in gingival crevicular fluid: association with clinical and microbiologic parameters. | soluble triggering receptor expressed on myeloid cells 1 (strem-1) belongs to the immunoglobulin superfamily and is involved in amplification of the inflammatory response to bacterial infection. this cross-sectional study aims to investigate the levels of strem-1 in gingival crevicular fluid (gcf) of individuals without periodontitis and with chronic periodontitis (cp) or generalized aggressive periodontitis (gagp) and their association with the levels of key periodontal pathogens in subgingival ... | 2014 | 23659423 |
| salivary carriage of periodontal pathogens in generalized aggressive periodontitis families. | generalized aggressive periodontitis (gap) is a multifactorial disease that shows a specific microbial profile and a familial aggregation. | 2014 | 23647376 |
| detection of eight periodontal microorganisms and distribution of porphyromonas gingivalis fima genotypes in chinese patients with aggressive periodontitis. | the microbiologic feature of aggressive periodontitis (agp) in chinese patients has not yet been determined. this study aims to investigate the prevalence of eight periodontal microorganisms and the distribution of the porphyromonas gingivalis fima genotype in a cohort of chinese patients with agp. | 2014 | 23646850 |
| prevalence of aggregatibacter actinomycetemcomitans, porphyromonas gingivalis and tannerella forsythia in japanese patients with generalized chronic and aggressive periodontitis. | this study aimed to investigate the prevalence and levels of major periodontal pathogens, aggregatibacter actinomycetemcomitans, porphyromonas gingivalis and tannerella forsythia in subgingival plaque samples of a group of japanese patients with aggressive periodontitis (agp) and chronic periodontitis (cp). a total of 40 patients with clinical diagnosis of agp or cp and 10 periodontally healthy volunteers were subjected to clinical and microbiological analysis. subgingival plaque samples were an ... | 2013 | 23608307 |
| detection of oral bacterial dna in synovial fluid. | as periodontal bacteria might be involved in the aetiology of rheumatic diseases, we analysed synovial fluid obtained from patients with rheumatoid arthritis (ra) and controls for the presence of dna of aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythia, and treponema denticola. | 2013 | 23534379 |
| cluster of bacteria associated with peri-implantitis. | information on the microbiota in peri-implantitis is limited. we hypothesized that neither gender nor a history of periodontitis/smoking or the microbiota at implants differ by implant status. | 2014 | 23527870 |
| subgingival aggregatibacter actinomycetemcomitans associates with the risk of coronary artery disease. | we investigated the association between angiographically verified coronary artery disease (cad) and subgingival aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, tannerella forsythia and treponema denticola. | 2013 | 23521427 |
| genetic analysis of porphyromonas gingivalis (fima), aggregatibacter actinomycetemcomitans, and red complex in coronary plaque. | the objective of the present study was to detect the presence of porphyromonas gingivalis (fima), aggregatibacter actinomycetemcomitans, and red complex in the coronary plaque of patients with coronary artery disease. | 2014 | 23447375 |
| prevalence of periodontal pathogens and metabolic control of type 1 diabetes patients. | the aim of the study was to evaluate the prevalence of periodontal pathogens aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythia and treponema denticola in subgingival plaque collected at different probing depths of type 1 diabetes patients with periodontal disease in correlation to metabolic control. | 2013 | 23413629 |
| influence of periodontal status and periodontopathogens on levels of oral human β-defensin-2 in saliva. | expression patterns of human β-defensin-2 (hbd-2) mrna or hbd-2 protein concentration and periodontal diseases have been a focus of scientific research. this study compares the salivary levels of hbd-2 protein concentration of healthy patients and patients with gingivitis and chronic periodontitis (cp) and correlates these levels with the presence of periodontopathogens. | 2013 | 23173827 |
| protective effect of topical cordia verbenacea in a rat periodontitis model: immune-inflammatory, antibacterial and morphometric assays. | this study evaluated the effects of c. verbenacea essential oil topically administered in a rat periodontitis model. | 2012 | 23171319 |
| screening for periodontopathogenic bacteria in severe chronic periodontitis in a moroccan population. | bacteria play an important role in destructive periodontitis. the aim of this study was to screen for five highly pathogenic bacteria: aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythia, and treponema denticola, in moroccan patients presenting with severe chronic periodontitis and to compare results with those of patients presenting with severe aggressive periodontitis. | 2012 | 23141872 |
| frequency of periodontal pathogens in equivalent peri-implant and periodontal clinical statuses. | this study tested the hypotheses that there is: (1) higher bacterial frequency in peri-implantitis/periodontitis, followed by mucositis/gingivitis and peri-implant/periodontal health; (2) similar bacterial frequency between comparable peri-implant and periodontal clinical statuses. | 2013 | 23127822 |
| possible translocation of periodontal pathogens into the lymph nodes draining the oral cavity. | numerous publications have reported the presence of periodontopathogenic bacteria in peripheral and central vascular lesions. however, it is unclear how this bacterial translocation occurs. the objective of this study was to investigate whether periodontopathic bacteria are translocated to lymph nodes proximal to the oral cavity. obtaining lymph node samples is not ethically feasible unless they are excised as part of the surgical management of patients with cancer. this study analyzed formalin- ... | 2012 | 23124752 |
| modeling susceptibility to periodontitis. | chronic inflammatory diseases like periodontitis have a complex pathogenesis and a multifactorial etiology, involving complex interactions between multiple genetic loci and infectious agents. we aimed to investigate the influence of genetic polymorphisms and bacteria on chronic periodontitis risk. we determined the prevalence of 12 single-nucleotide polymorphisms (snps) in immune response candidate genes and 7 bacterial species of potential relevance to periodontitis etiology, in chronic periodo ... | 2013 | 23100272 |
| clinical and microbiological changes after minimally invasive therapeutic approaches in intrabony defects: a 12-month follow-up. | this 12-month randomized, controlled trial evaluated the clinical effects and microbiological changes of minimally invasive nonsurgical and surgical approaches for the therapy of intrabony defects. | 2013 | 23053707 |
| reduction of salivary arginine catabolic activity through periodontal therapy. | salivary enzymes may be used to diagnose periodontal conditions. salivary arginase activity (saa) is related to susceptibility to bacterial infection. therefore, the aim of this controlled interventional study was to determine the saa before and after non-surgical periodontal therapy. | 2012 | 23041992 |
| detection and enumeration of periodontopathogenic bacteria in subgingival biofilm of pregnant women. | the aim of this study was to use the fluorescence in situ hybridization (fish) technique to test the hypothesis of qualitative and quantitative differences of 8 periodontopathogens between pregnant and non-pregnant women. this cross-sectional study included 20 pregnant women in their second trimester of pregnancy and 20 non-pregnant women. probing depth, bleeding on probing, clinical attachment level, and presence of calculus were recorded. subgingival plaque samples were collected and the fish ... | 2012 | 23018230 |
| a double-blind randomized placebo-controlled study on the clinical and microbial effects of an essential oil mouth rinse used by patients in supportive periodontal care. | this 3-month double-blind randomized placebo-controlled study evaluated the clinical and microbial effects of an essential oil mouth rinse used as an adjunct to mechanical plaque control by patients in supportive periodontal care. | 2013 | 22998386 |
| quantification of periodontopathic bacteria in saliva using the invader assay. | when quantifying periodontopathic bacteria, it is important to use a convenient method that does not produce false negative results. the invader assay is a convenient method because it does not involve gene amplification. the purpose of this study was to evaluate the validity of the invader assay to quantify periodontopathic bacteria. the invader technology was applied in quantifying five periodontopathic bacteria (aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, tannerella forsy ... | 2012 | 22996215 |
| do elderly edentulous patients with a history of periodontitis harbor periodontal pathogens? | the presence of periodontal pathogens in the oral cavity may impact implant survival. therefore, this study aimed to determine the prevalence of campylobacter rectus, porphyromonas gingivalis, aggregatibacter actinomycetemcomitans, prevotella intermedia, tannerella forsythia, treponema denticola, eikenella corrodens, and parvimonas micra in a specific elderly population with a history of periodontitis who have never worn dentures. | 2012 | 22988660 |
| periodontal pathogen load and increased antibody response to heat shock protein 60 in patients with cardiovascular disease. | to determine the relationship between periodontal pathogen load and anti-human heat shock protein 60 (hhsp60) antibodies in patients with established cardiovascular disease (cvd). | 2012 | 22882677 |
| clinical and microbiological parameters in patients with self-ligating and conventional brackets during early phase of orthodontic treatment. | to determine the effect of different bracket designs (conventional brackets and self-ligating brackets) on periodontal clinical parameters and periodontal pathogens in subgingival plaque. | 2013 | 22765511 |
| [amalgam, composite and compomer: microbiological study]. | restorative materials have different consequences on the periodontium. the surface of these materials may influence gingival health and cause in some instances gingival inflammation. the purpose of this study was to investigate and compare, in a healthy periodontium, intracrevicular plaque bacteria (aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, prevotella intermedia, tannerella forsythensis and treponema denticola), at day 0 and at 6 months, around subgingivally located amalga ... | 2012 | 22715643 |
| subgingival microbiota from cebus apella (capuchin monkey) with different periodontal conditions. | this present study evaluated the subgingival microbiota of the cebus apella with different periodontal conditions kept by the tufted capuchin monkey procreation center (são paulo state university - unesp) or free-ranging monkeys. for this purpose, clinical specimens of subgingival biofilm were collected from 52 monkeys, of both genders, 40 kept in captivity and 12 free-ranging monkeys. the primates were submitted to periodontal evaluation and biofilm samples were transferred to vmga iii transpor ... | 2012 | 22710412 |
| a common periodontal pathogen has an adverse association with both acute and stable coronary artery disease. | the aim of this study was to investigate the association between angiographically verified coronary artery disease (cad) and salivary levels of four major periodontal pathogens. | 2012 | 22704805 |
| peripheral arterial disease associated with caries and periodontal disease. | peripheral arterial disease (pad) is an important cardiovascular disorder of the peripheral arteries. chronic infections, such as periodontitis, may play an important role in the etiology and pathophysiology of pad and other cardiovascular conditions. recently, streptococcus mutans has been found with high frequency in atheromatous plaques. the aim of this study is to evaluate the possible clinical and microbiologic association between pad and periodontitis and dental caries. | 2013 | 22680302 |
| effect of azithromycin, as an adjunct to nonsurgical periodontal treatment, on microbiological parameters and gingival crevicular fluid biomarkers in generalized aggressive periodontitis. | emingil g, han b, özdemir g, tervahartiala t, vural c, atilla g, baylas h, sorsa t. the effect of azithromycin, as an adjunct to nonsurgical periodontal treatment, on microbiological parameters and gingival crevicular fluid biomarkers in generalized aggressive periodontitis. j periodont res 2012; 47: 729-739. © 2012 john wiley & sons a/s background and objective: to study the effectiveness of azithromycin in combination with nonsurgical periodontal therapy on clinical and microbiological parame ... | 2012 | 22571226 |
| subgingival microbial profiles as diagnostic markers of destructive periodontal diseases: a clinical epidemiology study. | to describe the subgingival microbial profiles of the major putative periodontal pathogens and investigate their role as diagnostic markers for destructive periodontal diseases in an untreated and isolated population. | 2013 | 22564019 |
| quantification of subgingival bacterial pathogens at different stages of periodontal diseases. | anaerobic gram-negative oral bacteria such as treponema denticola, aggregatibacter actinomycetemcomitans, porphyromonas gingivalis, tannerella forsythia, campylobacter rectus, and fusobacterium nucleatum are closely associated with periodontal diseases. we measured the relative population (bacterial levels) of these oral pathogens in subgingival tissues of patients at different stages of korean chronic periodontal diseases. we divided the individuals into those with chronic gingivitis (g), moder ... | 2012 | 22526568 |
| microbial profiles of patients seeking treatment for periodontitis. influence of origin, smoking and age? | we assessed the potential influence of the origin, the smoking status and the age on subgingival microbial profiles of subjects seeking periodontal care in switzerland today. | 2012 | 22419513 |
| distribution of periodontopathic bacterial species in dogs and their owners. | presently, a large number of individuals consider their companion animals as family members and have close contact with them in daily life. the purpose of the present study was to analyze the distribution of periodontopathic bacterial species in oral specimens taken from dogs and their owners. | 2012 | 22417880 |
| pdt in non-surgical treatment of periodontitis in hiv patients: a split-mouth, randomized clinical trial. | the aim of this study was to evaluate the clinical and microbiological effect of photodynamic therapy (pdt) in the non-surgical treatment of periodontitis in hiv patients. | 2012 | 22407618 |
| oral microbiota in swiss adolescents. | the purpose of the study was to determine the prevalence of different oral microbes in gingival plaque samples and in samples from the dorsum of the tongue in a swiss adolescent population. | 2013 | 22371122 |
| [effect of periodontal surgery on the subgingival periodontal microbiota in artificial class iii furcation defects: an experimental study in monkeys]. | this study was to longitudinally evaluate the change of prevalence of five periodontal putative pathogens in the subgingival plaque of artificial class iii furcation defects at the three time-points, including before the establishment of furcation defects, before and 6 months after periodontal surgery. | 2012 | 22353894 |
| azithromycin as an adjunctive treatment of generalized severe chronic periodontitis: clinical, microbiologic, and biochemical parameters. | this study examines the efficacy of azithromycin in combination with non-surgical periodontal therapy on clinical and microbiologic parameters and gingival crevicular fluid (gcf) matrix metalloproteinases-8 (mmp-8) levels over 6 months in patients with severe generalized chronic periodontitis (cp). | 2012 | 22324488 |
| the combination of amoxicillin and metronidazole improves clinical and microbiologic results of one-stage, full-mouth, ultrasonic debridement in aggressive periodontitis treatment. | the aim of the present study is to assess clinical, microbiologic, and immunologic benefits of amoxicillin/metronidazole (am) when performing full-mouth ultrasonic debridement (fmud) in generalized aggressive periodontitis (gagp) treatment. | 2012 | 22288485 |
| detection rates of presumptive periodontal pathogens in subgingival plaque samples of untreated periodontitis using either four or six pooled samples. | a comparison of the detection frequency and number of periodontal pathogens in patients with aggressive or generalized, severe chronic periodontitis using a gene-probe analysis. | 2010 | 25427269 |
| structural and functional characterization of nanu, a novel high-affinity sialic acid-inducible binding protein of oral and gut-dwelling bacteroidetes species. | many human-dwelling bacteria acquire sialic acid for growth or surface display. we identified previously a sialic acid utilization operon in tannerella forsythia that includes a novel outer membrane sialic acid-transport system (nanou), where nano (neuraminate outer membrane permease) is a putative tonb-dependent receptor and nanu (extracellular neuraminate uptake protein) is a predicted susd family protein. using heterologous complementation of nanou genes into an escherichia coli strain devoid ... | 2014 | 24351045 |
| structure of ragb, a major immunodominant outer-membrane surface receptor antigen of porphyromonas gingivalis. | porphyromonas gingivalis is the main causative agent of periodontitis. it deregulates the inflammatory and innate host immune responses through virulence factors, which include the immunodominant outer-membrane surface receptor antigens a (pgraga) and b (pgragb), co-transcribed from the rag pathogenicity island. the former is predicted to be a ton-dependent porin-type translocator but the targets of this translocation and the molecular function of pgragb are unknown. phenomenologically, pgragb h ... | 2016 | 26441291 |
| tlr4, nod1 and nod2 mediate immune recognition of putative newly identified periodontal pathogens. | periodontitis is a polymicrobial inflammatory disease that results from the interaction between the oral microbiota and the host immunity. although the innate immune response is important for disease initiation and progression, the innate immune receptors that recognize both classical and putative periodontal pathogens that elicit an immune response have not been elucidated. by using the human oral microbe identification microarray (homim), we identified multiple predominant oral bacterial speci ... | 2016 | 26177212 |
| a microbiological profile of unexposed and exposed pulp space of primary endodontic infections by checkerboard dna-dna hybridization. | the aim of this study was to evaluate, by checkerboard dna-dna hybridization, the composition of the microbiota of primary endodontic infections in cases associated with exposed (n = 30) and unexposed (n = 30) pulp space. | 2012 | 22703649 |
| tannerella forsythia strains display different cell-surface nonulosonic acids: biosynthetic pathway characterization and first insight into biological implications. | tannerella forsythia is an anaerobic, gram-negative periodontal pathogen. a unique o-linked oligosaccharide decorates the bacterium's cell surface proteins and was shown to modulate the host immune response. in our study, we investigated the biosynthesis of the nonulosonic acid (nulo) present at the terminal position of this glycan. a bioinformatic analysis of t. forsythia genomes revealed a gene locus for the synthesis of pseudaminic acid (pse) in the type strain atcc 43037 while strains fdc 92 ... | 2017 | 27986835 |
| common polymorphisms in the ifi16 and aim2 genes are associated with periodontal disease. | we investigated the single nucleotide polymorphism (snp) context of a previously identified periodontitis-associated locus and examined its association with microbial, biological and periodontal disease clinical parameters. | 2017 | 28387608 |
| behavior of two tannerella forsythia strains and cell surface mutants in multispecies oral biofilms. | as a member of subgingival multispecies biofilms, tannerella forsythia is commonly associated with periodontitis. the bacterium has a characteristic cell surface (s-) layer modified with a unique o-glycan. both the s-layer and the o-glycan were analyzed in this study for their role in biofilm formation by employing an in vitro multispecies biofilm model mimicking the situation in the oral cavity. different t. forsythia strains and mutants with characterized defects in cell surface composition we ... | 2017 | 28382776 |
| dental plaque microbial profiles of children from khartoum, sudan, with congenital heart defects. | few studies have focused on the bacterial species associated with the deterioration of the dental and gingival health of children with congenital heart defects (chd). the aims of this study were (1) to examine the dental plaque of children with chd in order to quantify bacterial load and altered bacterial composition compared with children without chd; and (2) to investigate the correlation between the level of caries and gingivitis and dental biofilm bacteria among those children. in this cross ... | 2017 | 28326155 |
| the current weight of evidence of the microbiologic profile associated with peri-implantitis: a systematic review. | there is currently no consensus regarding microorganisms that may be considered true peri-implant pathogens. therefore, the aim of this systematic review is to determine the weight of evidence for microorganisms related to peri-implantitis based on results of association studies. | 2016 | 27420109 |
| periodontal pathogens and risk of incident cancer in postmenopausal females: the buffalo osteoperio study. | extraoral translocation of oral bacteria may contribute to associations between periodontal disease and cancer. the associations among the presence of three orange-complex periodontal pathogens (fusobacterium nucleatum, prevotella intermedia, and campylobacter rectus), two red-complex periodontal pathogens (porphyromonas gingivalis and tannerella forsythia), and cancer risk were investigated. | 2016 | 26513268 |
| quantitative analysis of periodontal pathogens in periodontitis and gingivitis. | periodontal tissues surround the teeth and provide their attachment. periodontal diseases include a mild and reversible form named gingivitis and periodontitis that is the main cause of tooth loss in adults. gingivitis, that affects gums and coronal junctional epithelium, as well as periodontitis, that is characterized by loss of connective tissue attachment, are caused by a persistent inflammatory response promoted by alteration of periodontal biofilm. the aim of the study was to test whether t ... | 2017 | 26511188 |
| microbiota at teeth and implants in partially edentulous patients. a 10-year retrospective study. | to determine the microbiota at implants and adjacent teeth 10 years after placement of implants with a sandblasted and acid-etched surface. | 2016 | 25827437 |
| influence of the periodontal status on the initial-biofilm formation on titanium surfaces. | dental implants will be exposed to a complex ecosystem once they are placed in the oral cavity. the bacterial colonization and biofilm formation on these devices will depend not only on the physicochemical surface implant properties but also on the periodontal health conditions of the patients, as these devices are exposed. | 2016 | 24995517 |
| epstein-barr virus associated peri-implantitis: a split-mouth study. | herpesviral-bacterial synergism may play a potential role in periodontitis and peri-implantitis (pi) etiopathogenesis. pi lesions can worsen depending on specific microbial challenge and host susceptibility. this cross-sectional split-mouth study aimed to substantiate herpesviral-bacterial co-infection in pi patients and assess associations with periodontopathogen salivary contamination. | 2015 | 24802631 |
| first cultivation of health-associated tannerella sp. hot-286 (bu063). | despite significant advances in recent years in culture-independent molecular microbiology methods, the detailed study of individual bacterial species still relies on having pure cultures in the laboratory. yet, more than a third of the approximately 700 bacterial taxa found in the human oral cavity are as yet uncultivated in vitro. one such taxon, tannerella sp. hot-286 (phylotype bu063), is the focus of much interest since it is associated with periodontal health, while tannerella forsythia, i ... | 2016 | 27193146 |
| molecular analysis of 16s rrna genes identifies potentially periodontal pathogenic bacteria and archaea in the plaque of partially erupted third molars. | small subunit rrna sequencing and phylogenetic analysis were used to identify cultivable and uncultivable microorganisms present in the dental plaque of symptomatic and asymptomatic partially erupted third molars to determine the prevalence of putative periodontal pathogens in pericoronal sites. | 2012 | 22326171 |
| the effects of stress hormones on growth of selected periodontitis related bacteria. | the focus of this study was to examine in vitro the effects of stress hormones (catecholamines: epinephrine, norepinephrine, dopamine and hydrocortisone: cortisol) on the growth of four anaerobic species of periodontitis-related bacteria (fusobacterium nucleatum, porphyromonas gingivalis, prevotella intermedia and tannerella forsythia) and one facultative anaerobic species (eikenella corrodens). bacterial growth was determined by two different methods: fluorescence in situ hybridization (fish), ... | 2013 | 24036419 |
| anaerobic and microaerophilic pathogens in the biofilm formation on voice prostheses: a pilot study. | voice rehabilitation with voice prostheses is a standard therapy in laryngectomized patients. biofilm formation on the surface of the voice prostheses causes device failure and requires frequent replacements. studies analyzing the biofilm of voice prostheses have mainly focused on aerobic bacteria. anaerobic bacteria as an integral part of the biofilms on voice prostheses have not been investigated yet. | 2012 | 22374743 |
| microbiomes of endodontic-periodontal lesions before and after chemomechanical preparation. | this study was conducted to evaluate the microbiomes of endodontic-periodontal lesions before and after chemomechanical preparation (cmp). | 2015 | 26521147 |
| identification of a novel n-acetylmuramic acid transporter in tannerella forsythia. | tannerella forsythia is a gram-negative periodontal pathogen lacking the ability to undergo de novo synthesis of amino sugars n-acetylmuramic acid (murnac) and n-acetylglucosamine (glcnac) that form the disaccharide repeating unit of the peptidoglycan backbone. t. forsythia relies on the uptake of these sugars from the environment, which is so far unexplored. here, we identified a novel transporter system of t. forsythia involved in the uptake of murnac across the inner membrane and characterize ... | 2016 | 27601356 |
| in vitro resistance testing of porphyromonas gingivalis, prevotella intermedia, and tannerella forsythia to triclosan. | to determine the sensitivity of porphyromonas gingivalis, prevotella intermedia, and tannerella forsythia to triclosan, and determine if these bacteria develop resistance to triclosan upon prolonged exposure. | 2016 | 27340161 |