| e.e.g. monitoring for the control of anaesthesia produced by the infusion of althesin in primates. | the continuous infusion of althesin under electroencephalographic (e.e.g.) control provided a constant level of light anaesthesia for periods of 1--5.5 h during experimental brain hypoxia in spontaneously breathing baboons and rhesus monkeys. polygraphic records (respiration, heart rate, arterial pressure, cerebral venous sinus pressure, end-tidal gas concentrations) and also estimation of blood-gas tensions, ph, and concentrations of pyruvate and lactate demonstrated a steady physiological stat ... | 1978 | 101225 |
| the neuroanatomy of amnesia. a critique of the hippocampal memory hypothesis. | the discovery that medial temporal lobe lesions produce amnesia in humans if the lesion extends sufficiently far posteriorly to include the hippocampus forms the keystone of the hippocampal memory hypothesis. strong supporting evidence comes from the occurrence of mammillary body disease in korsakoff's psychosis. disease of the posterior cerebral artery confirmed the observations on the medial temporal lobectomies by showing that pathology in the ventromedial quadrant of the temporal lobe produc ... | 1978 | 101278 |
| the intrinsic connections of the cortex of area 4 of the monkey. | the intrinsic connections of area 4 of the monkey have been investigated with axonal degeneration methods after the placement of microelectrode lesions within the cortex. the fibre degeneration is restricted to within a few millimetres of the damage and is asymmetrically distributed in the form of an ellipse with its long axis anteroposteriorly. the same pattern is found in all topographic subdivisions of the motor cortex. there are two distinct zones of degeneration, dense fine terminal degener ... | 1978 | 101281 |
| an electron microscopic study of the termination of intracortical axons upon betz cells in area 4 of the monkey. | after small lesions within the cortex of area 4 of the monkey degenerating axon terminals have been seen with the electron microscopy to contact the cell bodies, proximal parts of the apical dendrites and initial segments of betz cells 0.5 to 2.5 mm from the damage. the degenerating axon terminals make symmetrical synapses which are presumed to be inhibitory in function. the degenerating terminals are probably from the axons of the basket cells described in golgi-impregnated material, and which ... | 1978 | 101282 |
| serum thyroxin levels during hyperthermia evoked in the monkey by intrahypothalamic injection of pge1, 5-ht or pyrogen. | serotonin (5-ht), prostaglandin e1 (pge1) or a bacterial pyrogen (e. coli or s. typhosa) was microinjected in a volume of 1.0--1.5 microliter into the hypothalamus of the unanesthetized monkey to evoke a long-term hyperthermia. samples of venous blood collected every 15 min, before, during and after each fever were analyzed by radioimmunoassay for plasma thyroxin levels. there was no statistically significant correlation between plasma thyroxin values and a given phase of the hyperthermic episod ... | 1978 | 101286 |
| hypocholesterolemic activities of lk-903 and clofibrate in miniature pigs, cynomolgus monkeys and beagle dogs. | | 1978 | 101309 |
| effect of psychosocial stimuli and limbic lesions on prolactin at rest and following stress. | many of the factors altering corticosterone in the rat have similar effects on prolactin. resting prolactin, like corticosterone, is higher in animals housed singly than in those multiply housed. unlike corticosterone, gentling did not lower prolactin. an exquisite sensitivity to environmental stimuli which results in rapid elevations in prolactin levels has been indentified in the rat which is considerably greater than that for corticosterone. like corticosterone, the pattern of prolactin stres ... | 1977 | 101322 |
| cell-mediated immune responses in owl monkeys (aotus trivirgatus) with trachoma to soluble antigens of chlamydia trachomatis. | the first temporal study of the cell-mediated immune responses (cmi) following ocular infections with chlamydia trachomatis is presented. we examined the cmi of owl monkeys infected with trachoma to soluble antigens of c. trachomatis by leucocyte migration inhibition (lif) and delayed hypersensitivity skin testing. delayed hypersensitivity of a systemic nature developed after a local eye infection in owl monkeys; clearance of inclusions from conjunctival cells coincided with the onset of this re ... | 1978 | 101327 |
| the effects of unilateral or bilateral removals of the second somatosensory cortex (area sii): a profound tactile disorder in monkeys. | three groups of monkeys were studied; one with bilateral removals of the second somatosensory projection cortex (sii); another with similar unilateral removals; and an unoperated control group. both lesion groups were significantly impaired on tasks of tactile learning and tactile retention. however, there were no differences between groups on the great majority of tasks of motor learning, nor on spatial alternation in the dark. the animals with unilateral removals were generally impaired whethe ... | 1978 | 101347 |
| disturbance of cage-finding in the monkey. | qualitative and quantitative observations were made on two monkeys with unilateral or bilateral removals of areas 5 and 7 of brodmann. the task was to return to the home cage in the light or in the dark. both animals were slower in the dark, and also qualitatively abnormal in the light. | 1978 | 101348 |
| the arrangement of the connective tissue in the stroma iridis of man and monkey. | | 1978 | 101386 |
| measurement of pain threshold by electrical stimulation of tooth pulp afferents in the monkey. | | 1978 | 101387 |
| antibodies to spermatozoa in male monkeys: mode of action. | | 1978 | 101391 |
| interceptive activity of azastene in rhesus monkeys. | azastene is an orally effective "luteolytic" agent in rhesus monkeys. in nonpregnant monkeys it reverses the human chorionic gonadotropin-stimulated increase in progesterone production and delay in the onset of menstruation, and, in inseminated monkeys, it prevents pregnancy if given for 5 days beginning on day 24 of the menstrual cycle. the drug is also effective in terminating pregnancy if given for 5 days beginning on approximately day 26, day 50, or day 80 of gestation. concurrent progestero ... | 1978 | 101392 |
| the diet and feeding behaviour of cercopithecus aethiops tantalus. | the feeding behaviour of representative groups of tantalus monkeys (cercopithecus aethiops tantalus) was observed during 1974-1975 in three habitats in cameroon. observations took place during the wet and dry seasons in sahelian savannah, guinea savannah and farmed forest. the tantalus monkeys were similar to other races of c.aethiops that have been studied in that they were omnivorous and lacked any narrow specialisations of either diet or feeding techniques. the dietary range was similar in al ... | 1978 | 101428 |
| influence of progesterone on sexual behavior in castrated male rhesus monkeys treated with testosterone. | | 1978 | 101436 |
| effect of testosterone propionate on electrical activity of brain in intact & gonadectomized rhesus monkeys. | | 1978 | 101442 |
| suppression of lymphocyte transformation by plasma from owl monkeys acutely infected with plasmodium falciparum. | plasma collected from owl monkeys during the acute phase of plasmodium falciparum infection was shown to adversely affect several in vitro responses which are considered to be correlates of cell-mediated immune functions of normal monkeys. in the presence of acute-phase plasma, response of normal monkey peripheral blood lymphocytes to stimulation with phytohemagglutinin, concanavalin a, and pokeweed mitogen was severely reduced, as was the ability of peripheral blood lymphocytes to respond to al ... | 1978 | 101455 |
| experimental production of respiratory tract disease in cebus monkeys after intratracheal or intranasal infection with influenza a/victoria/3/75 or influenza a/new jersey/76 virus. | a total of 28 cebus monkeys were inoculated intratracheally or intranasally with 10(6) 50% tissue culture infective doses of a/new jersey/76 virus or 10(7) 50% tissue culture infective doses of a/victoria/75 virus, and 8 additional monkeys received sterile allantoic fluid. each of the animals became infected as evidenced by a serological response and/or shedding of the virus. of the 10 animals inoculated intratracheally with a/victoria/75 virus, 8 developed a systemic illness, and pulmonary infi ... | 1978 | 101457 |
| mortality of monkeys after exposure to fission neutrons and the effect of autologous bone marrow transplantation. | in order to assess the risk of exposure to ionizing radiation in man, and to evaluate the results of therapeutic measures, the mortality of rhesus monkeys irradiated with x-rays and fission neutrons and the effect of autologous bone marrow transplantation have been investigated. the ld50/30d values for x- and neutron-irradiated monkeys amount to 525 and 260 rad respectively, resulting in an r.b.e. of approximately 2 for the occurrence of the bone marrow syndrome. protection of the animals by aut ... | 1978 | 101475 |
| experimental pyelonephritis in the monkey. vi. infection of infants versus adults. | pyelonephritis followed ureteral inoculation of bacteria in both infant and adult monkeys. because of the frequency of reflux in infants this was done by bladder inoculation, although ureteral inoculation was necessary in adults. the longer duration of bacteriuria in infants may be attributable to a relative immunodeficiency. | 1978 | 101479 |
| construction of hemibladders and cutaneous vesicostomies for bilateral renal function studies. a new technique in macaca arctoides. | a surgical technique for the construction of hemibladders and permanent cutaneous vesicostomies in macaca arctoides is described. serial studies of renal function were performed in sedated monkeys before and 1 or more months after division of the bladder. the results of the studies confirm our previous observation that renal function in monkeys is comparable to that in man and show that (i) the surgical procedure is successful in the majority of instances; (ii) simultaneous determinations of ren ... | 1978 | 101480 |
| chronic pyelonephritis. an electron microscopic study in nonhuman primates. | the rhesus monkey (macaca mulatta) proved to be a successful model for the ultrastructural study of ascending nonobstructive pyelonephritis. the most severe kidney damage occurred where the inflammatory response was greatest, and these areas overlaid a dilated or clubbed calyx. the most prominent ultrastructural changes were in the renal tubular cells that showed swollen mitochondria with ruptured inner membranes, dilated endoplasmic reticulum, and flocculent and irregular basal laminae. no reco ... | 1978 | 101481 |
| monkey pepsinogens and pepsins. iii. carbohydrate moiety of japanese monkey pepsinogens and the amino acid sequence around the site of its attachment to protein. | purified japanese monkey pepsinogens i and ii contain carbohydrate as a part of the enzyme molecule. by gel filtration on sephadex g-100, chromatography on de-32 cellulose, and polyacrylamide disc gel electrophoresis, the carbohydrate moiety could not be separated from the enzyme protein, and the content did not decrease on repeated chromatography. glycopeptides were obtained by successive digestion of pepsinogens with thermolysin and aminopeptidases and isolated by chromatography on sephadex g- ... | 1978 | 101535 |
| maternal separations in rhesus monkeys within a social context. | | 1978 | 101552 |
| replantation of mature teeth without endodontics in monkeys. | the purpose of this study was to evaluate the histologic response after replantation of mature, developed teeth without endodontic treatment in monkeys. to serve as experimental controls, the other replanted teeth received endodontic treatment. no significant differences were noted in the rate and quality of periodontal tissues healing between the endodontically and the nonendodontically treated teeth in monkeys sacrificed at 5, 7, and 14 days, and at 1, 2, and 3 months after replantation. howev ... | 1978 | 101567 |
| some observations on cochlear mechanics. | a set of experiments was conducted using the mössbauer effect to determine the vibratory characteristics of the basilar membrane, reissner's membrane, the malleus, incus, and oval window in squirrel monkey. a few measurements were also made in guinea pig in the basal cochlear region. the nonlinear vibration properties of the basilar membrane are described in detail for the midfrequency region in the squirrel monkey. only in this region have nonlinear effects been observed. a comparison of mechan ... | 1978 | 101571 |
| squirrel monkey temporary threshold shift from 48-h exposures to low-frequency noise. | five squirrel monkeys were exposed for 1, 2, 4, 8, 16, 24, and 48 h to a 375--750-hz band noise at an overall spl of 95 db. the tts4.5 growth pattern for the 750-hz test frequency was biphasic and did not reach an asymptote after 48 h of exposure. for all exposures, the mean thresholds of the five monkeys returned to within 5 db of the preexposure mean 20 h after exposure. recovery curves from all exposures at the 750-hz test frequency appeared biphasic. increasing spl from 95 to 105 db increase ... | 1978 | 101572 |
| a study of the effect of slow-reacting substances of anaphylaxis on the rhesus monkey airway. | slow-reacting substance of anaphylaxis (srs-a) generated from rat peritoneal mast cells was aerosolized to the airways of a group of rhesus monkeys with established airway responses to ascaris antigen. a selective effect of srs-a on pulmonary resistance and a lesser but significant effect on compliance was observed which differed from antigen, histamine, carbocholine, or prostaglandin (pg) f2alpha responses. the airway recovery from the pr change is slower than that from histamine and simulated ... | 1978 | 101573 |
| specific change in the direction of prostaglandin synthesis by intra-uterine tissues of the rhesus monkey (macaca mulatta) during late pregnancy. | the rates of production of prostaglandin e (pge), prostaglandin f (pgf) and 13, 14-dihydro-15-oxo-prostaglandin f (pgfm) by intra-uterine tissues from pregnant monkeys in vitro have been determined using a method of tissue superfusion. the amnion, chorion, placenta, decidua basalis, decidua parietalis and myometrium were obtained at caesarean section during late pregnancy. production of pge by all tissues was significantly lower at term than during late pregnancy, whereas production of pgf by th ... | 1978 | 101638 |
| effect of hypotension induced by sodium nitrocyanoferrate (iii) on the release of arginine-vasopressin in the unanaesthetized monkey. | | 1978 | 101639 |
| concentrations of oestradiol-17beta and progesterone in the peripheral plasma of the cynomolgus monkey (macaca fascicularis) in relation to the length of the menstrual cycle and its component phases. | ninety-three female cynomolgus monkeys were monitored throughout 647 menstrual cycles; 93.2% of these cycles were 22--37 days long and were normally distributed, with a mean of 29.2 days. menstrual bleeding generally lasted for 3--5 days and was not related to the length of the cycle. the levels of progesterone and oestradiol-17beta in the plasma were measured during the menstrual cycle in 30 monkeys. the concentration of oestradiol-17beta reached a mid-cycle peak on day 11 or 12 of the cycle. t ... | 1978 | 101640 |
| production of thromboxane b2 by the intra-uterine tissues from late pregnant rhesus monkeys (macaca mulatta) in vitro. | the rates of production of thromboxane b2 in vitro by intra-uterine tissues obtained from late pregnant monkeys by caesarean section have been determined. the general quantitative order of rates of production was decidua basalis = decidua parietalis greater than placenta greater than chorion greater than amnion = myometrium. myometrial production of thromboxane b2 was greater at term than during late pregnancy; no other tissue showed a significant trend with advancing gestation. these data demon ... | 1978 | 101641 |
| trauma from occlusion in monkeys. | traumatic occlusion was induced in monkeys by insertion of bridges raising the bite. both incisors and molars were used as abutments. observation periods ranged from 7 to 24 months. no appreciable effect of the trauma on the apical proliferation of the crevicular epithelium was found. the results were the same in monkeys with or without marginal gingival inflammation before the trauma was induced. | 1978 | 101646 |
| [studies on metabolism of prazepam. iv. metabolic fate of prazepam in monkeys (author's transl)]. | | 1978 | 101652 |
| effects of some psychotropic drugs on m-wave and operant behavior in the squirrel monkey. | the effects of low doses of nabilone, chlorpromazine, pentobarbital, meprobamate, diazepam, chlordiazepoxiode and d-amphetamine on behavioral responding to cues signalling the availability of food rewards, and on the m-wave, an evoked cortical potential previously reported to reflect the conditioned incentive value of the cues were determined in the squirrel monkey. nabilone and chlorpromazine simultaneously depressed both the m-wave and behavior. pentobarbital, meprobamate, diazepam and chlordi ... | 1978 | 101654 |
| influences of season and age on maturation in vitro of rhesus monkey oocytes. | oocytes obtained from antral follicles of adult and adolescent rhesus monkeys during the annual breeding season extruded polar bodies in vitro at significantly higher rates (50--60%) than oocytes from animals of similar age during the non-breeding season ((20--30%) or from infant and prepubertal females at any time of the year (20--30%). the proportion of oocytes degenerating in culture was greatest in groups where maturation was highest. | 1978 | 101658 |
| unilateral forelimb deafferentation in the monkey: purposive movement. | monkeys with unilateral dorsal rhizotomy c2-t3 used their denervated limbs to retrieve unseen food pellets when movements of the intact contralateral limb were rendered ineffective by enclosure of the hand within a container. even after protracted use in this condition, however, the deafferented limb ceased to be used in the test situation when the intact arm was released. these findings cast doubt on interpretations of lack of use of a unilaterally dorsal rhizotomized limb as being due to cross ... | 1978 | 101662 |
| transmission of hepatitis b to the rhesus monkey. studies on the humoral and cell-mediated immune response. | the susceptibility of the rhesus monkey (macaca mulatta) to hepatitis b virus was enhanced by the induction of chronic infection with plasmodium inuei. | 1978 | 101663 |
| perception of sounds used in species-specific communication: the auditory cortex and beyond. | the auditory cortex, located in the superior temporal gyrus, has been studied in squirrel monkeys with respect to its role in detecting species-specific vocalizations. single neurons tested with selected vocalizations from the species' repertoire have been grouped into seven functional categories. each category reflects a different level of processing with regard to vocalizations and artificial sounds. it is argued that, while the auditory cortex has the capability to detect and distinguish spec ... | 1978 | 101665 |
| possible errors in identification of squirrel monkeys (saimiri sciureus) from different south american points of export. | we conducted karyological studies on one colony consisting of 12 colombian and 34 bolivian squirrel monkeys and a second colony of 47 monkeys imported into the united states between 1968 and 1974 through six importers. all animals in the first colony showed six acrocentric pairs of chromosomes. bolivian monkeys were phenotypically distinguishable by their large size and coloration. in the second colony, 19 peruvian, seven colombian, five bolivian and six guyanan monkeys were correctly identified ... | 1978 | 101666 |
| blood groups of macaques:a comparative study. | distribution of the human-type and of the simian-type blood groups in rhesus, crab-eating, bonnet, pig-tailed and stump-tailed macaques revealed significant similarities and differences among these species. human-type a--b-o blood groups cut across taxonomic lines and seem less value for taxonomic purposes than the simian-type blood groups detected by cross-reacting isoimmune rhesus monkey sera. | 1978 | 101667 |
| banding patterns of the chromosomes of two new karyotypes of the owl monkey, aotus, captured in panama. | two new chromosome complements of aotus trivirgatus griseimembra are described making a total of five different karyotypes observed in this subspecies inhabiting panama and the northwestern part of colombia, south america. detailed comparisons of the g-banded chromosomes of these five karyotypes suggest that the polymorphism of chromosome numbers 56 and 55 in panamanian aotus and 54, 53, and 52 in colombian aotus stems primarily from a robertsonian translocation mechanism involving pairs b13 and ... | 1978 | 101668 |
| growth and hematologic development of the patas monkey (erythrocebus patas) to one year of age. | data from 338 blood samples of 31 patas monkeys is presented to show the normal hematolgoic development from birth to one year of age, and is compared to 120 samples from normal adults. marked changes in hematocrit, hemoglobin, red cell numbers, and leukocyte distribution which occurred during the first month were followed by a slow progression to adult values. body weight data is also presented which shows a linear growth rate during the first year of life. | 1978 | 101669 |
| the course of development of glucose intolerance in the monkey (macaca mulatta). | longitudinal studies of the rhesus monkey reveal a syndrome of diabetes mellitus in those that become middle-aged and obese. the sequence of events in the development of the disease progresses from normoinsulinemia with normoglycemia through stages of hyperinsulinemia followed by below normal insulin levels with hyperglycemia and glycosuria. we believe the rhesus to be an excellent nonhuman primate model for maturity-onset diabetes in humans. | 1978 | 101670 |
| an antigen resembling hl-a7 on the leukocytes of vervet monkeys. | human leukocyte typing sera of known specificities were used to test the leukocyte antigens of vervet monkeys. the results suggest that these leukocytes contained an antigen resembling the hl-a7 antigen of human leukocytes. this is similar to a previous observation with leukocytes from baboons. these findings are consistent with the suggestion that the 4a/4b complex is the precursor substance from which the other specificities have evolved. | 1978 | 101671 |
| weight and size of the placenta in cynomolgus monkeys (macaca fascicularis). | a gross anatomical survey of the placental development was carried out in 24 cynomolgus monkeys (macaca fascicularis) of 4, 5, 6, 7, 8, 9, 10, 15 and 20 weeks of gestational age. eight of the 24 placentas examined were found to be single discoidal and the remaining 16 bidiscoidal. the weight and size of placentas of each animal were measured. the average weight of the 20th week placentas was about 94 times heavier than that of the 4th week ones; the average diameter of the former was about 5 tim ... | 1978 | 101705 |
| gamma hydroxybutyrate in the monkey. iii. effect of intravenous anticonvulsant drugs. | monkeys were treated intravenously with various anticonvulsant drugs before and after the intravenous administration of gamma hydroxybutyrate (ghb). continuous electroencephalographic (eeg) and temperature monitoring was performed throughout all experiments. the ghb-induced eeg changes were abolished by ethosuximide and clonazepam, marginally improved by diazepam, and unaffected by phenobarbital. the ghb-induced myoclonic jerks were abolished by ethosuximide, significantly improved by diazepam, ... | 1978 | 101897 |
| gamma hydroxybutyrate in the monkey. iv. dopaminergic mechanisms. | the electrical seizure activity and trancelike state induced in the rhesus monkey by gamma-hydroxybutyrate (ghb) were abolished by dextroamphetamine. dextroamphetamine blockade of this neurophysiologic effect was overcome with chlorpromazine, a dopamine receptor blocker. these results suggest that the electroencephalographic (eeg) and behavioral effects of ghb are related to effects on dopaminergic systems. such a relationship, if substantiated by further studies, might indicate that anticonvuls ... | 1978 | 101898 |
| functional rehabilitation of ankylosed temporomandibular joints. | successful chrome-cobalt prostheses have been used to replace the condyle and glenoid fossa in six young macaca irus monkeys. in one group of two animals the left temporomandibular joint was replaced; in the second group the right joint and in the third group both temporomandibular joints were replaced. neither masticatory function nor ability to open or close the mouth was affected, and all the animals remained in excellent health, living in the colony for 9 to 10 months. a similar surgical pro ... | 1978 | 101929 |
| pulpal and periodontal effects of electrosurgery involving cervical metallic restorations. | the pulpal and periodontal effects of electrosurgery involving teeth restored with class v cervical amalgams and nonrestored teeth were evaluated in three cynomolgus monkeys. electrosurgical current was delivered for 1 second with a fully rectified unit at an output intensity consistent with normal clinical usage. experimental conditions included electrosurgery involving restored teeth, electrosurgery involving unrestored enamel, restored teeth not subjected to electrosurgery, and teeth which we ... | 1978 | 101933 |
| effects of combinations of phencyclidine and pentobarbital on schedule-controlled behavior in the squirrel monkey. | three squirrel monkeys trained on a variable interval schedule of food presentation were used to examine the interaction between phencyclidine (pcp) and pentobarbital (pb). first, dose-response curves for each drug given alone were obtained. pcp caused small response rate increases at low doses, and a dose-dependent decrease in responding at higher doses. pb caused only dose-dependent decreases in responding. the pb dose-response curve was then redetermined in the presence of four doses of pcp. ... | 1978 | 101988 |
| effects of passive immunization against morphine on heroin self-administration. | antimorphine antibodies produced in rhesus monkeys immunized with morphine-6-hemisuccinate-bsa were passively administered to recipient monkeys trained to self-administer heroin and cocaine. following antibody administration, changes in heroin self-administration behavior were observed which were similar to those achieved with low doses of naloxone. both manipulations increased heroin self-administration without affecting cocaine responding. | 1978 | 101989 |
| short-term memory in the rhesus monkey: effects of dopamine blockade via acute haloperidol administration. | the effects of dopaminergic blockade on recent or short-term memory (stm) were evaluated in test-sophisticated rhesus monkeys. each monkey was tested under several doses of the antidopaminergic haloperidol (0.006 to 0.05 mg/kg), in an automated, delayed-response procedure. the same procedure and test apparatus had previously been used to demonstrate profound stm impairments in aged rhesus monkeys and strikingly similar deficits in young monkeys given the anticholinergic scopolamine. the results ... | 1978 | 101990 |
| a sensitive radioimmunoassay for 6-keto-prostaglandin f1alpha: preliminary observations on circulating concentrations. | a radioimmunoassay for 6-keto-prostaglandin f1alpha (6-keto-pgf1alpha) is reported. the mean least detectable mass of 6-keto-pgf1alpha is 1.45 pg and the mean mass of added 6-keto-pgf1alpha required to displace zero-point binding by 50% is 94.2 pg. cross-reactivities of the antiserum with all the prostaglandins and related compounds tested are less than 0.1% except for pge2 and pgf2alpha which are respectively 0.16% and 0.80%. the assay is both accurate and reproducible and measured levels are i ... | 1978 | 102000 |
| neuronal plasticity in primate telencephalon: anomalous projections induced by prenatal removal of frontal cortex. | when the dorsolateral prefrontal cortex in one hemisphere of a rhesus monkey is resected 6 weeks before birth and the fetus survives to postnatal ages, neurons of the corresponding cortex in the intact hemisphere issue a greatly expanded projection to the contralateral caudate nucleus in addition to a normal projection to the ipsilateral caudate. the enhancement of the crossed prefronto-caudate pathway after prenatal neurosurgery provides direct evidence for lesion-induced neuronal rearrangement ... | 1978 | 102031 |
| ultradian cortisol rhythms in monkeys: synchronized or not synchronized? | | 1978 | 102033 |
| spinothalamic tract neurons in the substantia gelatinosa. | the substantia gelatinosa of the mammalian spinal cord is generally believed to be a closed system; that is its neurons are thought to project only to the substantia gelatinosa of the same or the contralateral side. experiments in monkeys, using injections of the marker enzyme horseradish peroxidase, show that at least some neurons of the substantia gelatinosa project to the thalamus and thus belong to the spinothalamic tract. such neurons include two cell types intrinsic to the gelatinosa, the ... | 1978 | 102034 |
| disposition of orf 9326, a novel contragestational steroid, in animals. | the disposition of orf 9326 [17beta-acetoxy-2alpha-chloro-3(p-nitrophenoxy) imino-5-androstane], an o-aryl oxime of 2beta-chlorodihydrotestosterone acetate, was studied in rats, dogs, monkeys and rabbits. intravenous administration of 3h-orf 9326 dissolved in peg-400 to rats, dogs and monkeys resulted in a rapid decline of radioactivity in blood followed by a terminal slope suggesting long retention of radioactivity. apparent half lives of radioactivity in blood were calculated to be from 50--9 ... | 1978 | 102053 |
| trichomonal granuloma of the pelvic cavity in a rhesus monkey. | | 1978 | 102073 |
| excretion and biotransformation of carboxymethyl-cysteine in rat, dog, monkey and man. | 1. following an oral dose of s-carboxymethyl [35s]cysteine monkey (rhesus and african green), rat, dog, and man excreted 77,88,95, and 100% respectively of the 35s radioactivity in urine and 7.0, 2.5, 0.7, and 0.3% in faeces during a 3 to 4 day period. 2. the principal drug-related components excreted were unchanged carboxymethylcysteine, dicarboxymethyl sulphide and inorganic sulphate. 3. rat, dog, and man excreted primarily dicarboxymethyl sulphide and unchanged carboxymethylcysteine and no in ... | 1978 | 102086 |
| motilin-, substance p- and somatostatin-like immunoreactivities in extracts from dog, tupaia and monkey brain and gi tract. | | 1978 | 102123 |
| experimental group b streptococcal infection in the rhesus monkey. i. disease production in the neonate. | group b streptococci (gbs) are responsible for serious infections of newborn infants. an experimental model for gbs infection was developed in the newborn rhesus monkey in order to obtain more information concerning the pathogenesis of such infections. a series of 29 newborn monkeys were inoculated with either type ic or type iii gbs or sterile broth. fatal neonatal meningitis without associated pneumonia was produced consistently following intracerebral inoculation with either type ic or type i ... | 1978 | 102197 |
| neural control of gonadotropin secretion in primates. | in the rhesus monkey, there is abundant evidence to indicate that ovarian secretions, mainly estradiol-17beta, control "tonic" as well as "cyclic" secretion of gonadotropins during the menstrual cycle. this mechanism of control ensures coordination of ovarian morphology and anterior pituitary secretory patterns. the primary site of action of estradiol in controlling both "tonic" and "cyclic" secretion of gonadotropins has been circumscribed to the medial basal hypothalamic-pituitary unit. a modu ... | 1978 | 102199 |
| retinal ganglion cell degeneration in experimental optic atrophy. | by ophthalmoscopic and histopathologic examinations at various intervals after retinal injury, we studied progressive ganglion cell atrophy following retinal photocoagulation in 25 owl monkey eyes. a reduced ganglion cell population was apparent within three to four weeks after the photocoagulation and was maximal by six weeks. | 1978 | 102201 |
| metric characteristics of the canine dental complex in prenatally androgenized female rhesus monkeys (macaca mulatta). | permanent maxillary canine teeth (c1) are appreciably larger in males than in females in most nonhominid anthropoidea. mandibular canines (c1) and mandibular first premolars (p3), against which c1 are sharpened in honing behavior, reflect commensurate sexual dimorphism. these three teeth constitute the canine dental complex. the canine complex crown metrics of seven mature genetically female rhesus macaques, androgenized by prenatal exposure to testosterone propionate, were compared with a contr ... | 1978 | 102208 |
| a quantitative estimation of the depletion of the granules of argyrophile cells in the gastrointestinal tract of reserpine treated rhesus monkeys. | the depletion of the granules of argyrophile cells following administration of reserpine has been studied at various levels of the gastrointestinal tract of the rhesus monkey. granulation of the cells has been estimated by the photometric method of singh(1976). the argyrophile cells that persist after reserpine administration show a statistically significant reduction in their granulation as compared to cells of untreated controls (p less than 0.001). | 1978 | 102216 |
| spermatophagy in the seminiferous tubules and excurrent ducts of the testis in rhesus monkey and in man. | the fine structure of cells capable of phagocytosing spermatozoa in the testes and epididymes of monkeys and men was studied by means of transmission and scanning electron microscopy. both resident cells, such as sertoli cells and epithelia of the rete testis, and free cells, such as macrophages (spermatophages) were found to phagocytose spermatozoa or fragments of spermatozoa in the seminiferous tubules and excurrent ducts. the spermatophages develop from precursor cells which invade the semini ... | 1978 | 102218 |
| estrogen and progesterone receptors in the female genital tract of humans and monkeys. | | 1977 | 102233 |
| effect of progestins on glucose and lipid metabolism. | gestamimetic amounts of progesterone enhance basal and glucose-stimulated insulin production. contraceptive doses of synthetic progestins cause a moderate increase or no change in glucose-stimulated insulin production, depending on route of administration and species tested. estrogens potentiate the insulinotropic effects of progesterone and the synthetic progestins. basal serum triglyceride concentrations are generally unaffected by progesterone or 17 alpha-acetoxyprogesterone treatment but may ... | 1977 | 102234 |
| a behavioral analysis of complete unilateral section of the pyramidal tract at the medullary level in macaca mulatta. | ten macaca mulatta monkeys were operantly conditioned to perform three motor paradigms designed to evaluate single and combination finger movements. eight of these monkeys were retested after left medullary pyramidotomy; 2 monkeys underwent left medullary pyramidotomy prior to conditioning. all animals were tested for three years after operation. monkeys with a completely sectioned medullary pyramid could, with time, perform difficult motor paradigms that required: (1) both individual and combin ... | 1978 | 102241 |
| scanning electron microscope observation of the seminal vesicle in the japanese monkey with special reference to intraluminal spermiophagy by macrophages. | the seminal vesicle of the adult japanese monkey was observed by scanning electron microscopy. a number of spermatozoa are found scattered on the luminal surface. some of them are normal in appearance, while others disintegrated. the epithelial cells bulging slightly into the lumen are devoid of cilia, but provided with diffusely distributed microvilli. the fracture surface reveals that the epithelium of the seminal vesicle consists of columnar epithelial cells with secretory activity and occasi ... | 1978 | 102301 |
| semi-automated detection of emesis in the rhesus monkey. | the use of a video recorder and the inclusion of a marker dye in material fed to rhesus monkeys has eliminated the need for the constant presence of an observer to detect an emetic response. | 1978 | 102332 |
| the use of standard and relaxed hybridization conditions to detect two classes of sequences related to type-d retroviruses in the dnas of primates. | using standard hybridization conditions (68 degrees c and 0.4 m sodium phosphate) and assaying for rnaase-resistant rna . dna duplexes in the presence of 2 x ssc (1 x ssc is 0.15 m nacl and 0.015 m sodium citrate), sequences representing approx. 20% of the mason-pfizer virus (mpv) genome have previously been shown to be endogenous in dnas of all old world monkeys examined (drohan, w., colcher, d., schochetman, g. and schlom, j. (1977) j. virol. 23, 36--43). we now report that titration of both t ... | 1978 | 102351 |
| influence of ovarian hormones on prolactin release in the rhesus monkey. | | 1978 | 102374 |
| arsenic excretion by monkeys dosed with arsenic-containing fish or with inorganic arsenic. | four adult female cynomolagus monkeys were given single oral dose of fish arsenic. 67% of the arsenic was excreted with the urine and 10% with the feces, essentially within 5 days post exposure. the same monkeys were later dosed with inorganic arsenic and 76% of it was excreted with the urine, and practically nil with the feces. | 1978 | 102385 |
| operant control of pyramidal tract neurons: the role of spinal dorsal columns. | a monkey was trained to control the firing patterns of precentral pyramidal tract neurons. the operant task was for the monkey to produce consecutive interspike intervals (isi) within a requisite range, or target. the mean time off-target (error) is used to quantify the accuracy of control the monkey could assert over each ptn. following partial destruction of the dorsal funiculi the number of ptns driven by peripheral stimuli greatly decreased. those ptns which remained responsive to peripheral ... | 1978 | 102407 |
| oculomotor nucleus afferents in the monkey demonstrated with horseradish peroxidase. | the afferents to the oculomotor nucleus were examined in the macaque monkey by means of horseradish peroxidase. the demonstration of afferents from the contralateral interstitial nucleus of cajal, and from the nearby rostral interstitial nucleus of the medial longitudinal fasciculus, predominantly ipsilateral to the injection site, confirms the significant role of these two regions as premotor structures. hrp label in the pretectal area was strictly confined to the olivary nucleus and the corres ... | 1979 | 102412 |
| evidence for the loss of x-cells of the retina after long-term ablation of visual cortex in monkeys. | | 1979 | 102413 |
| expression of ricinus communis receptors on epithelial cells in oral carcinomas and oral wounds. | the histological distribution of receptors for ricinus communis fraction 1 (rca1) in oral carcinomas and in oral epithelial cells during wound healing has been studied by use of fluorescein-tagged rca1. biopsies from 15 human oral carcinomas and adjacent normal mucosa showed rca1 receptors at the cell membranes in the basal and spinous layer of the normal epithelium, whereas receptors could not be demonstrated in invading islands of the tumors. in healing oral wounds from eight humans and three ... | 1978 | 102424 |
| studies on the immunogenicity of protamines in humans and experimental animals by means of a micro-complement fixation test. | a complement fixation study with human, monkey and rabbit sera, using purified sperm nuclear basic proteins as antigens, led to the following conclusions. (1) protamines, the sperm-specific basic nuclear proteins, may be immunogenic in mammalians. (2) antibodies detected in the indirect immunofluorescence test on human swollen sperm heads in sera from infertile and vasectomized men, are directed primarily against human protamines. (3) the results obtained suggested that differences in the immuni ... | 1978 | 102475 |
| post-vasectomy autoimmunity to protamines in relation to the formation of granulomas and sperm agglutinating antibodies. | the development of antibodies reacting with nuclear antigens was studied in sera from vasectomized men and monkeys (obtained at intervals of up to 2 and 4 years, respectively, after the operation), by means of a comparative fluorescence study on swollen nuclei of somatic cells, human and salmon spermatozoa. about 30% of forty-seven vasectomized men developed antibodies to protamines. also four out of fifteen monkeys, vasectomized with or without ligation, developed antibodies reacting with prota ... | 1978 | 102476 |
| chemical occlusion of rhesus monkey oviducts with chloroquine. | fertility control through chemical occlusion of the oviducts with chloroquine was investigated in rhesus monkeys (m.m.). chloroquine was instilled retrograde through the tubal ostium after laparotomising the monkeys as a 10, 50 and 100% suspension (w/v) in aqueous carboxymethyl cellulose (cmc) solution which was used as a carrier vehicle. complete occlusion of the fallopian tubes at the uterotubal junction and also the intramural portions resulted in 15 days after a single instillation. | 1978 | 102485 |
| [goal-directed behavior of experimental monkeys (macaca mulatta) defined by the relative novelty of the experimental situation]. | | 1978 | 102506 |
| taurine and other free amino acids in milk of man and other mammals. | taurine and other free amino acids have been determined in human milk of a number of other species. taurine is the most abundant free amino acid in the milk of the gerbil, mouse, cat, dog and rhesus monkey. taurine is the second most abundant amino acid in the milk of the rat, baboon, chimpanzee, sheep, java monkey and man. taurine is not a major constituent in the milk of the guinea pig, rabbit, cow and horse. the milk of each species has a characteristic free amino acid pattern which may be an ... | 1978 | 102507 |
| operant methodology in the study of learning. | a series of experiments is described in which operant methodology is used to study the effects of drugs on "learning." emphasis is placed on the technique of repeated acquisition as a behavioral baseline for studying this type of transition state. in this technique, each subject is required to learn a new discrimination each session. multiple-schedule procedures are also described in which acquisition is compared to a "performance" task, where the discrimination is the same each session. the lea ... | 1978 | 102510 |
| potent depletion of 5ht from monkey whole blood by a new 5ht uptake inhibitor, paroxetine (fg 7051). | the potent 5-hydroxytryptamine (5ht) uptake inhibitor fg 7051 (paroxetine, inn) was administered to rhesus monkeys in doses of 1.0, 2.5 or 7.5 mg/kg by oral gavage once daily for 13 weeks. blood samples for analysis of 5ht in whole blood and paroxetine in plasma were taken prior to and after 1, 4 and 13 weeks of treatment. the lowest dose 1 mg/kg caused 30% depletion of 5ht in whole blood with a level of paroxetine in plasma below 2 ng/ml. doses of 2.5 mg/kg produced an 85% depletion of 5ht and ... | 1978 | 102515 |
| bone growth aud development of secondary ossification centers of extremities in the cynomolgus monkey (macaca fascicularis). | the development of so-called long bones in the extremity has been studied roentgenographically in forty-seven males and fifty-one females cynomolgus monkeys bred and reared at the national institute of health. the age of the females ranged from five months to eight years and nine months, and that of the males was from four months to seven years. in addition, the fetuses of six to twenty weeks of gestation age were examined for the time of appearance of ossification centers. as the biological par ... | 1978 | 102516 |
| organization of the mammalian red nucleus and its interconnections with the cerebellum. | the red nucleus in monkeys and rats consists of a magnocellular, rubrospinal portion which receives its cerebellar information from the nucleus interpositus, and a parvocellular, rubroolivary portion which receives cerebellar afferents from the nucleus lateralis. distinct interpositorubrospinal and dentatorubroolivary projections are therefore common to these 2 species. | 1978 | 102524 |
| topographic localisation of insulinogenic and insulinoprival areas in the hypothalamus. | electrical stimulation of hypothalamic areas through stereotaxically implanted electrodes were carried out in conscious male rhesus monkeys. there was a significant increase in immunoreactive insulin (iri) following laterla hypothalamus (lha) stimulation. an opposite response was obtained from ventromedial hypothalamus (vmh). thus, insulinogenic and insulinoprival responses were obtained from feeding and satiety, suggesting a significant role of insulin in the regulation of food intake. | 1978 | 102526 |
| a method to collect cervical smears from small breeds of monkeys. | a simple method is described to collect cervical smears and to have a clear view of cervix for small breed of monkeys. this method was found useful to collect adequate cytology smears with good preservation of cellular morphology. | 1978 | 102527 |
| [interaction between corticofugal impulses from the s1 region and responses in the caudate nucleus of monkeys to nonsomatic stimuli]. | | 1978 | 102538 |
| the relation of the shrieking sounds emitted by a capuchin monkey, cebus griseus f. cuvier 1819 (1824), to the time of sunrise. | | 1978 | 102539 |
| [genetic limitations of erythrocyte lysis by bacteria of the genus salmonella]. | lytic effect of salmonella bacteria on the erythrocates of 1301 humans (including 150 twins), 1059 hens, 600 mice, 33 guinea pigs, 47 rabbits, 22 horses, 16 sheeps, 7 dogs, 2 cats and 2 monkeys was investigated. erythrocytes of all horses, guinea pigs and rabbits tested appeared to be sensible. the same cells of humans, sheeps, hens, dogs, monkeys and cats turned to be either sensible, or stable. human erythrocytes were the most stable. erythrocytes of humans having had typhus or other salmonell ... | 1978 | 102562 |
| social organization and social behavior in two subspecies of squirrel monkeys (saimiri sciureus). | social organization and social behavior were examined in two subspecies of squirrel monkeys which differ markedly in the degree of sexual dimorphism. the bolivian squirrel monkeys, the subspecies with greater sexual dimorphism, manifested a sexually segregated form of social organization, while the social organization of the guyanese monkeys was sexually integrated. dominance relationships were found to reflect these patterns of sexual segregation or integration; in the bolivian social groups se ... | 1978 | 102567 |
| food transfer by wild titi monkeys (callicebus torquatus torquatus). | the behaviours and food types associated with wild titi monkey food transfer are described and analyzed. food transfer is not considered altruistic, and possible benefits are explored by examining the context and consequences of food transfer. | 1978 | 102568 |
| some effects of living conditions upon the pattern of growth in the stumptail macaque (macaca arctoides). | somatometric and weight measurements of stumptail macaques (macaca arctoides) bred in various environmental conditions are presented. environmental parameters may influence the pattern of growth in slowing down the 'growth rate' of monkeys bred in restricted laboratory environment as compared with monkeys bred in 'optimal' captive conditions: their subadult and adult linear dimensions are smaller. | 1978 | 102573 |
| ultrastructure of tissue in intrabony and subperiosteal porous ceramic implants. | porous ceramic (al2o3) implants with pore size of 100--750 micron were placed intrabony in the maxilla and subperiosteally in the mandible of three adult monkeys. after observation periods of 10, 11 and 12 months, the animals were perfused with 1.7% glutaraldehyde and the jaws processed for electron microscopy. tissue ingrowth into the pores was observed in all the specimens. the implant pores facing the host bone contained bone tissue to a depth of approximately 1 mm, while only unmineralized t ... | 1978 | 102603 |
| chloroquine retinopathy in the rhesus monkey. | chloroquine was administered intramuscularly 5 days a week to rhesus monkeys for as long as 4 1/2 years. no clinical, fluorescein angiographic, or electrophysiological evidence of retinal damage was observed. yet chloroquine/chloroquine byproduct analysis of the ocular tissues revealed an enormous binding capacity of the pigmented tissues of the eye (choroid plus rpe, ciliary body, and iris) with eventual accumulation observed in the retina. despite the normal ophthalmic appearance and function, ... | 1978 | 102610 |
| the distribution of the chorda tympani in the middle ear area in man and two other primates. | a serial section study of the distribution of the chorda tympani in the middle ear area was carried out in man, baboon and monkey. the tissues innervated by the chorda tympani could be related to a branchiomeric pattern. the early branches distributed post-trematic facial nerve fibres to hyoid arch tissues, where they were joined by elements from glossopharyngeal and vagus nerves. the rest of the distribution was to structures derived from mandibular arch tissue where branches of the auriculotem ... | 1978 | 102629 |