| acrolein and thiol-reactive electrophiles suppress allergen-induced innate airway epithelial responses by inhibition of duox1 and egfr. | acrolein is a major thiol-reactive component of cigarette smoke (cs) that is thought to contribute to increased asthma incidence associated with smoking. here, we explored the effects of acute acrolein exposure on innate airway responses to two common airborne allergens, house dust mite and alternaria alternata, and observed that acrolein exposure of c57bl/6 mice (5 ppm, 4 h) dramatically inhibited innate airway responses to subsequent allergen challenge, demonstrated by attenuated release of th ... | 2016 | 27612966 |
| comparison of antifungal activity of extracts from different juglans regia cultivars and juglone. | this study discusses the similarities and differences between the antifungal activity of extracts from walnut green husks of lake, koszycki, uo1, uo2 and non-grafted cultivars as well as juglone against the plant pathogenic fungi such as alternaria alternata, rhizoctonia solani, botrytis cinerea, fusarium culmorum, phytophthora infestans as well as ascosphaera apis causing chalkbrood disease in honey bees. the obtained data show that the antifungal activities of the extracts do not always depend ... | 2016 | 27744101 |
| specific antibodies for the detection of alternaria allergens and the identification of cross-reactive antigens in other fungi. | the mould alternaria alternata is an important source of respiratory allergens. a. alternata extracts show great variations regarding allergenic potency. the aim of this study was to generate antibody probes specific for important alternaria allergens and to use them to study allergen expression, depending on different culture conditions, as well as to search for cross-reactive allergens in other mould species. | 2016 | 27780168 |
| sulfoglucosides as novel modified forms of the mycotoxins alternariol and alternariol monomethyl ether. | the mycotoxins alternariol and alternariol-9-o-methyl ether have recently been reported to be extensively conjugated with glucose and malonyl glucose in tobacco suspension cells. however, only trace amounts of glucosylated conjugates were detected in tomatoes inoculated with alternaria alternata in the present study. instead, mostly sulfate conjugates were observed. in studies using cultures of a. alternata and incubations of alternariol and alternariol-9-o-methyl ether with tomato tissue in the ... | 2016 | 27776211 |
| laea and vea are involved in growth morphology, asexual development, and mycotoxin production in alternaria alternata. | alternaria alternata is a common filamentous fungus that contaminates various fruits, grains and vegetables causing important economic losses to farmers and the food industry. a. alternata is a mycotoxigenic mould, which may jeopardize human and animal health. two of the most common a. alternata mycotoxins found in food and feed are alternariol and alternariol monomethyl ether. in this study we examined the role of laea and vea, two regulatory proteins belonging to the velvet family, which have ... | 2016 | 27642688 |
| development of loop-mediated isothermal amplification (lamp) assay for the rapid detection of alternaria alternata. | fungi of the alternaria genus are associated with allergic diseases, with alternaria alternata being one of the most prevalent species. a. alternata has been frequently reported as the etiologic agent of hypersensitivity pneumonitis, allergic rhinosinusitis, bronchial asthma, and other diseases. in this study, we developed a loop-mediated isothermal amplification (lamp) assay and a real-time pcr assay to detect low levels of a. alternata in herbal tea samples. the lamp assay can detect as little ... | 2016 | 27760588 |
| comparative evaluation of biochemical changes in tomato (lycopersicon esculentum mill.) infected by alternaria alternata and its toxic metabolites (tea, aoh, and ame). | in the present study, we have evaluated the comparative biochemical defense response generated against alternaria alternata and its purified toxins viz. alternariol (aoh), alternariol monomethyl ether (ame), and tenuazonic acid (tea). the necrotic lesions developed due to treatment with toxins were almost similar as those produced by the pathogen, indicating the crucial role of these toxins in plant pathogenesis. an oxidative burst reaction characterized by the rapid and transient production of ... | 2016 | 27713751 |
| leaf spot disease adversely affects human health-promoting constituents and withanolide biosynthesis in withania somnifera (l.) dunal. | the present work investigates the implication of leaf spot disease on the antioxidant potential and commercial value of pharmaceutically important constituents of withania somnifera, a high-valued medicinal plant. | 2017 | 27709727 |
| bioprospecting for secondary metabolites in the entomopathogenic bacterium photorhabdus luminescens subsp. sonorensis. | crude extracts of in vitro and in vivo cultures of two strains of photorhabdus l. sonorensis (enterobacteriaceae) were analyzed by tlc, hplc-uv and lc-ms. nine unique compounds with mass/charge ratios (m/z) ranging from 331.3 to 713.5 were found in ms analyses. bioactivity of extracts was assessed on a selection of plant pathogens/pests and non-target species. caborca strain extracts showed the highest activity against helicoverpa zea (lepidoptera: noctuidae) neonates at all concentrations teste ... | 2016 | 27702563 |
| identification of cyclic lipopeptides produced by bacillus vallismortis r2 and their antifungal activity against alternaria alternata. | to identify the different antifungal biomolecules produced by isolate bacillus vallismortis r2 and analyse their effect on alternaria alternata, a common pathogen causing black point disease of wheat. | 2017 | 27665751 |
| arabidopsis responds to alternaria alternata volatiles by triggering plastid phosphoglucose isomerase-independent mechanisms. | volatile compounds (vcs) emitted by phylogenetically diverse microorganisms (including plant pathogens and microbes that do not normally interact mutualistically with plants) promote photosynthesis, growth, and the accumulation of high levels of starch in leaves through cytokinin (ck)-regulated processes. in arabidopsis (arabidopsis thaliana) plants not exposed to vcs, plastidic phosphoglucose isomerase (ppgi) acts as an important determinant of photosynthesis and growth, likely as a consequence ... | 2016 | 27663407 |
| draft genome sequence of alternaria alternata isolated from onion leaves in south africa. | alternaria alternata (fr.) keissler strain ppri 21032 was isolated from onion leaves collected in roodeplaat, pretoria, south africa. the whole genome of this strain was sequenced and produced a total of 33.12 mb with a gc content of 50.9%. the whole genome comprises 11,701 predicted coding sequences. | 2016 | 27660793 |
| genome-wide identification and expression analysis of the apple asr gene family in response to alternaria alternata f. sp. mali. | the aba/water stress/ripening-induced (asr) gene family exists universally in higher plants, and many asr genes are up-regulated during periods of environmental stress and fruit ripening. although a considerable amount of research has been performed investigating asr gene response to abiotic stresses, relatively little is known about their roles in response to biotic stresses. in this report, we identified five asr genes in apple (malus × domestica) and explored their phylogenetic relationship, ... | 2016 | 27653246 |
| feeding patterns of tyrophagus putrescentiae (sarcoptiformes: acaridae) indicate that mycophagy is not a single and homogeneous category of nutritional biology. | mycophagy should not be considered as a single and homogeneous category of nutritional biology due to the specific symbiotic chitinolytic bacteria associated with mites and fungi. to test interaction among mites, fungi, and chitinolytic bacteria, experiments were conducted on the model species tyrophagus putrescentiae (schrank). mucor sp, alternaria alternata, penicillium claviforme, p. griseofulvum, and verticillium sp. were plated onto malt agar and offered to t. putrescentiae in the laborator ... | 2016 | 27638952 |
| pulmonary ormdl3 is critical for induction of alternaria-induced allergic airways disease. | genome-wide association studies have identified the orm (yeast)-like protein isoform 3 (ormdl3) gene locus on human chromosome 17q to be a highly significant risk factor for childhood-onset asthma. | 2016 | 27623174 |
| allergen-specific ige measurement: intermethod comparison of two assay systems in diagnosing clinical allergy. | our aim was to examine the performance of immulite 2000 assay for specific ige (sige) by comparing it with immunocap technology in light of a clinical background. | 2016 | 27604174 |
| il-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha. | il-33 plays an important role in the initiation of type-2 immune responses, as well as the enhancement of type 2 effector functions. engagement of the il-33 receptor on macrophages facilitates polarization to an alternative activation state by amplifying il-4 and il-13 signaling to il-4rα. il-4 and il-13 also induce macrophage proliferation but il-33 involvement in this process has not been rigorously evaluated. as expected, in vivo delivery of il-33 induced il-4rα-dependent alternative macropha ... | 2016 | 27592711 |
| psc-afp from psoralea corylifolia l. overexpressed in pichia pastoris increases antimicrobial activity and enhances disease resistance of transgenic tobacco. | psc-afp, isolated from the seeds of psoralea corylifolia l., is an antimicrobial protein with trypsin inhibitor activity. its encoding gene was cloned by 3'- rapid amplification of cdna ends (race) combined with y-shaped adaptor-dependent extension (yade) method. the gene psc-afp encodes a protein of 203 amino acids with a deduced signal peptide of 24 residues. the growth inhibition effect exerted by the heterologously expressed psc-afp in pichia pastoris revealed that the recombinant psc-afp in ... | 2017 | 27587300 |
| genomic and transcriptomic analyses of the tangerine pathotype of alternaria alternata in response to oxidative stress. | the tangerine pathotype of alternaria alternata produces the a. citri toxin (act) and is the causal agent of citrus brown spot that results in significant yield losses worldwide. both the production of act and the ability to detoxify reactive oxygen species (ros) are required for a. alternata pathogenicity in citrus. in this study, we report the 34.41 mb genome sequence of strain z7 of the tangerine pathotype of a. alternata. the host selective act gene cluster in strain z7 was identified, which ... | 2016 | 27582273 |
| preparation of enantiomerically pure (s)-(-)-1-(1'-naphthyl)-ethanol by the fungus alternaria alternata. | (s)-(-)-1-(1'-napthyl)-ethanol (s-ne) is an important intermediate for the preparation of mevinic acid analogs, which is used for the treatment of hyperlipidemia. the objectives of the study were to isolate a microorganism that could effectively reduce 1-acetonaphthone (1-acn) to s-ne, to determine the influence that the physicochemical parameters would have on the reduction by the isolated microorganism, and to attempt large-scale studies with the microorganism. over the years fungi have been c ... | 2016 | 27581384 |
| [cross-reactivity in allergic fungal sinusitis. case report]. | the presence of allergic mucin in allergic fungal sinusitis (afs) is a manifestation that identifies it as a hypersensitivity process. afs has a phenomenon of cross-reactivity to ige-bound proteins having at least two shared epitopes. | 2016 | 27560920 |
| metabolic changes in euphorbia palusrtis latex after fungal infection. | the variations of metabolic profile of the latex of wild-growing euphorbia palustris was carried out using multivariate analysis of (1)h nmr spectral data. one population was infected with fungi fusarium sporotrichioides, fusarium proliferatum and alternaria alternata, while the other consisted of healthy plant species. the non-polar metabolites of latex extracts such as benzoyl ingenol-laurate, amyrin decadienoate esters, cis-1,4-polyisoprene, and 24-methylenecycloartanol were identified using ... | 2016 | 27553715 |
| a pair of new polyketide enantiomers from three endolichenic fungal strains nigrospora sphaerica, alternaria alternata, and phialophora sp. | a pair of new enantiomeric polyketides, (-)- and (+)-nigrosporaol a (1a and 1b), along with one related known compound, (+)-alternarienoic acid (2), were isolated from three endolichenic fungal strains, nigrospora sphaerica (no.83-1-1-2), alternaria alternata (no.58-8-4-1), and phialophora sp.(no.96-1-8-1). their structures, including the absolute configurations, were elucidated on the basis of spectroscopic methods, x-ray diffraction analysis, and the modified mosher's method. | 2016 | 27534128 |
| are epiphytic microbial communities in the carposphere of ripening grape clusters (vitis vinifera l.) different between conventional, organic, and biodynamic grapes? | using barcoded pyrosequencing fungal and bacterial communities associated with grape berry clusters (vitis vinifera l.) obtained from conventional, organic and biodynamic vineyard plots were investigated in two subsequent years at different stages during berry ripening. the four most abundant operational taxonomic units (otus) based on fungal its data were botrytis cinerea, cladosporium spp., aureobasidium pullulans and alternaria alternata which represented 57% and 47% of the total reads in 201 ... | 2016 | 27500633 |
| putative nonribosomal peptide synthetase and cytochrome p450 genes responsible for tentoxin biosynthesis in alternaria alternata zj33. | tentoxin, a cyclic tetrapeptide produced by several alternaria species, inhibits the f₁-atpase activity of chloroplasts, resulting in chlorosis in sensitive plants. in this study, we report two clustered genes, encoding a putative non-ribosome peptide synthetase (nrps) tes and a cytochrome p450 protein tes1, that are required for tentoxin biosynthesis in alternaria alternata strain zj33, which was isolated from blighted leaves of eupatorium adenophorum. using a pair of primers designed according ... | 2016 | 27490569 |
| the effect of calprotectin on tslp and il-25 production from airway epithelial cells. | calprotectin is a heterodimer complex of the s100a8 and s100a9 proteins, and has various functions as an innate mediator at the sites of inflammation. the aim of this study was to elucidate the roles of calprotectin in the eosinophilic chronic rhinosinusitis (ecrs). | 2017 | 27475624 |
| characterization and antimicrobial properties of cotton fabric loaded with green synthesized silver nanoparticles. | in the present study, antimicrobial formulations, based on silver nanoparticles (agnps) and butyl acrylate binder, were prepared and applied to a cotton fabric, followed by gamma-radiation or thermal curing, to protect it against the undesirable microbial effects. agnps were prepared by a biological method, using the biomass filtrate of fungus alternaria alternata. nanoparticles were characterized by uv-vis spectroscopy, transmission electron microscopy, energy dispersive x-ray spectroscopy, and ... | 2016 | 27474632 |
| direct versus sequential immunoglobulin switch in allergy and antiviral responses. | allergy is characterized by ige production to innocuous antigens. the question whether the switch to ige synthesis occurs via direct or sequential pathways is still unresolved. the aim of this work was to analyze the distribution of immunoglobulins (ig) to house dust mite d. farinae and a. alternata fungus in allergic children with primarily established diagnosis and compare it to epstein-barr antiviral (ebv) response in the same patients. in allergy patients the only significant difference was ... | 2016 | 27471213 |
| effect of 1-methylcyclopropene on the development of black mold disease and its potential effect on alternariol and alternariol monomethyl ether biosynthesis on tomatoes infected with alternaria alternata. | ethylene is a naturally produced plant regulator involved in several plant functions, such as regulation of fruit ripening. inhibition of ethylene perception by using 1-methylcyclopropene (1-mcp) slows down the ripening of the fruit maintaining its quality and freshness. the use of 1-mcp is a commercial strategy commonly used in the food industry to extend the postharvest life of several fruits, including tomatoes. to assess how 1-mcp affected infection by alternaria alternata on tomatoes, three ... | 2016 | 27454782 |
| antifungal effect and protective role of ursolic acid and three phenolic derivatives in the management of sorghum grain mold under field conditions. | in this study, investigation was carried out under in vitro as well as field conditions to explore inhibitors of sorghum grain mold. phytochemicals, viz., methyl trans-p-coumarate (aic-1), methyl caffeate (aic-2), syringic acid (aic-3), and ursolic acid (ua), at different concentrations (500, 750, and 1000 ppm) were tested on spore germination of alternaria alternata, curvularia lunata, fusarium moniliforme, f. pallidoroseum, and helminthosporium sp. significant growth inhibition (p < 0.001) was ... | 2016 | 27447843 |
| tomato plant proteins actively responding to fungal applications and their role in cell physiology. | the pattern of protein induction in tomato plants has been investigated after the applications of pathogenic and non-pathogenic fungal species. moreover, particular roles of the most active protein against biological applications were also determined using chromatographic techniques. alternaria alternata and penicillium oxalicum were applied as a pathogenic and non-pathogenic fungal species, respectively. protein profile analysis revealed that a five protein species (i.e., protein 1, 6, 10, 12, ... | 2016 | 27445848 |
| physical mapping of black spot disease resistance/susceptibility-related genome regions in japanese pear (pyrus pyrifolia) by bac-fish. | black spot disease, caused by alternaria alternata japanese pear pathotype, is one of the most harmful diseases in japanese pear cultivation. in the present study, the locations of black spot disease resistance/susceptibility-related genome regions were studied by fluorescence in situ hybridization using bac clone (bac-fish) on japanese pear (pyrus pyrifolia (burm. f.) nakai) chromosomes. root tips of self-pollinated seedlings of 'osa gold' were used as materials. chromosome samples were prepare ... | 2016 | 27436955 |
| comparative analysis of secretome profiles of manganese(ii)-oxidizing ascomycete fungi. | fungal secretomes contain a wide range of hydrolytic and oxidative enzymes, including cellulases, hemicellulases, pectinases, and lignin-degrading accessory enzymes, that synergistically drive litter decomposition in the environment. while secretome studies of model organisms such as phanerochaete chrysosporium and aspergillus species have greatly expanded our knowledge of these enzymes, few have extended secretome characterization to environmental isolates or conducted side-by-side comparisons ... | 2016 | 27434633 |
| impact of phase i metabolism on uptake, oxidative stress and genotoxicity of the emerging mycotoxin alternariol and its monomethyl ether in esophageal cells. | studies on the genotoxicity of alternaria mycotoxins focus primarily on the native compounds. alternariol (aoh) and its methyl ether (ame) have been reported to represent substrates for cytochrome p450 enzymes, generating hydroxylated metabolites. the impact of these phase i metabolites on genotoxicity remains unknown. in the present study, the synthesis and the toxicological effects of the metabolites 4-hydroxy alternariol (4-oh-aoh) and 4-hydroxy alternariol monomethyl ether (4-oh-ame) are pre ... | 2017 | 27422292 |
| does adenoid hypertrophy affect disease severity in children with allergic rhinitis? | our study aims to evaluate the presence of adenoid hypertrophy (ah) in children with allergic rhinitis (ar) and the association of ah disease severity and clinical laboratory finding from retrospective, cross-sectional, and nonrandomized trial. the study included 566 children being treated and followed up for allergic rhinitis. skin prick test for the same allergens was performed for all patients. adenoid tissue was analyzed by an ent specialist and the diagnosis was confirmed based on the patie ... | 2017 | 27405740 |
| arginine acts as an inhibitor of the biosynthesis of several mycotoxins. | it is well known that the type and the availability of nitrogen have a great influence on the biosynthesis of certain mycotoxins. here it is shown that some amino acids have no influence, some others strongly support and a third group inhibits the biosynthesis of ochratoxin (ota) by penicillium nordicum even in a complex medium, such as pda. arginine (arg) is one of the strong ota inhibiting amino acids. it was shown that arg not only inhibits ota in penicillium but also citrinin (cit) biosynthe ... | 2016 | 27400452 |
| a phenazine-1-carboxylic acid producing polyextremophilic pseudomonas chlororaphis (mcc2693) strain, isolated from mountain ecosystem, possesses biocontrol and plant growth promotion abilities. | the genus pseudomonas is known to comprise a huge diversity of species with the ability to thrive in different habitats, including those considered as extreme environments. in the present study, a psychrotolerant, wide ph tolerant and halotolerant strain of pseudomonas chlororaphis gbpi_507 (mcc2693), isolated from the wheat rhizosphere growing in a mountain location in indian himalayan region (ihr), has been investigated for its antimicrobial potential with particular reference to phenazine pro ... | 2016 | 27394000 |
| clinical distinctness of allergic rhinitis in patients with allergy to molds. | introduction. molds are a very diverse group of allergens. exposure and sensitization to fungal allergens can promote the development and worsening of allergic rhinitis (ar). objective. the natural course of allergic rhinitis was compared between a group of patients with allergy to molds and patients with ar to other allergens as the control groups. material and methods. the study group consisted of 229 patients, with a mean age of 27.4 ± 6.5 yrs. the study group was compared to groups of ar pat ... | 2016 | 27340656 |
| orthologous allergens and diagnostic utility of major allergen alt a 1. | hypersensitivity to fungi is associated with rhinoconjunctivitis and asthma. for some fungi, such as alternaria alternata (a. alternata), the symptoms of asthma are persistent, increasing disease severity and the risk of fatal outcomes. there are a large number of species of fungi but knowledge of them remains limited. this, together with the difficulties in obtaining adequate standardized extracts, means that there remain significant challenges in the diagnosis and immunotherapy of allergy asso ... | 2016 | 27334781 |
| critical role of coi1-dependent jasmonate pathway in aal toxin induced pcd in tomato revealed by comparative proteomics. | alternaria alternata f.sp. lycopersici (aal) toxin induces programmed cell death (pcd) in susceptible tomato (solanum lycopersicum) leaves. jasmonate (ja) promotes aal toxin induced pcd in a coi1 (coronatine insensitive 1, ja receptor)-dependent manner by enhancement of reactive oxygen species (ros) production. to further elucidate the underlying mechanisms of this process, we performed a comparative proteomic analysis using tomato jasmonic acid insensitive1 ( jai1), the receptor mutant of ja, a ... | 2016 | 27324416 |
| image gallery: cutaneous infections caused by alternaria alternata and mucor irregularis 1 year apart in a patient with iatrogenic cushing syndrome. | | 2016 | 27317292 |
| antifungal activity of lactobacillus sp. bacteria in the presence of xylitol and galactosyl-xylitol. | lactic acid fermentation is a natural method of antimicrobial food protection. antagonistic activity of lactobacillus sp. bacteria, taking part in this process, is directed mainly against the same or other microorganisms. in this work we determine the impact of the presence of xylitol and galactosyl-xylitol on the antagonistic activity of 60 lactobacillus sp. strains against indicator molds (alternaria alternata, alternaria brassicicola, aspergillus niger, fusarium latenicum, geotrichum candidum ... | 2016 | 27294124 |
| molecular phylogeny, diversity, and bioprospecting of endophytic fungi associated with wild ethnomedicinal north american plant echinacea purpurea (asteraceae). | the endophytic fungal community associated with the ethnomedicinal plant echinacea purpurea was investigated as well as its potential for providing antifungal compounds against plant pathogenic fungi. a total of 233 endophytic fungal isolates were obtained and classified into 42 different taxa of 16 genera, of which alternaria alternata, colletotrichum dematium, and stagonosporopsis sp. 2 are the most frequent colonizers. the extracts of 29 endophytic fungi displayed activities against important ... | 2016 | 27273012 |
| synthesis and in vitro antifungal activities of novel benzamide derivatives containing a triazole moiety. | the study reported the synthesis and antifungal activities in vitro against six phytopathogenic fungi of 17 novel n-[2-hydroxy-3,3-dimethyl-2-[(1h-1,2,4-triazol-1-yl)methyl]butyl]benzamide derivatives. all the target compounds were synthesized and elucidated by means of ms, high resolution (hr)-ms, ir, (1)h- and (13)c-nmr analysis. the results showed that almost all the derivatives exhibited good activities against each of the tested fungi at the concentration of 50 µg/ml. among them, 6h display ... | 2016 | 27250796 |
| cholinesterase inhibitor (altenuene) from an endophytic fungus alternaria alternata: optimization, purification and characterization. | the aim of this study was to screen endophytic fungi isolated from vinca rosea for their potential to produce acetylcholinesterase (ache) inhibitors. | 2016 | 27248836 |
| mouse models of asthma. | allergic asthma is a chronic inflammatory disease of the conducting airways characterized by the presence of allergen-specific ige, th2 cytokine production, eosinophilic airway inflammation, bronchial hyperreactivity, mucus overproduction, and structural changes in the airways. investigators have tried to mimic these features of human allergic asthma in murine models. whereas the surrogate allergen ovalbumin has been extremely valuable for unravelling underlying mechanisms of the disease, murine ... | 2016 | 27248433 |
| the clinical differences of asthma in patients with molds allergy. | bronchial asthma is an increasing problem worldwide. the course of bronchial asthma is dependent on the type of inducing allergens. the differences between the clinical features of asthma in patients with monovalent allergies to molds and with other allergies were explored. | 2016 | 27238165 |
| characterization and comparison of the cpk gene family in the apple (malus × domestica) and other rosaceae species and its response to alternaria alternata infection. | as one of the ca2+ sensors, calcium-dependent protein kinase (cpk) plays vital roles in immune and stress signaling, growth and development, and hormone responses, etc. recently, the whole genome of apple (malus × domestica), pear (pyrus communis), peach (prunus persica), plum (prunus mume) and strawberry (fragaria vesca) in rosaceae family has been fully sequenced. however, little is known about the cpk gene family in these rosaceae species. in this study, 123 cpk genes were identified from fiv ... | 2016 | 27186637 |
| leukotriene e4 elicits respiratory epithelial cell mucin release through the g-protein-coupled receptor, gpr99. | cysteinyl leukotrienes (cyslts), leukotriene c4 (ltc4), ltd4, and lte4 are proinflammatory lipid mediators with pathobiologic function in asthma. lte4, the stable cyslt, is a weak agonist for the type 1 and type 2 cyslt receptors (cysltrs), which constrict airway smooth muscle, but elicits airflow obstruction and pulmonary inflammation in patients with asthma. we recently identified gpr99 as a high-affinity receptor for lte4 that mediates cutaneous vascular permeability. here we demonstrate that ... | 2016 | 27185938 |
| activation of the nrf2-are pathway by the alternaria alternata mycotoxins altertoxin i and ii. | the mycotoxins altertoxin i and ii (atx i and ii) are secondary metabolites produced by alternaria alternata fungi and may occur as food and feed contaminants, especially after long storage periods. although the toxic potential of altertoxins has been previously investigated, little is known about the pathways that play a role in their intracellular metabolism. in order to identify potential targets of atx i and atx ii, the two toxins were tested for interaction with the nuclear factor erythroid ... | 2017 | 27178040 |
| membrane proteome profiling of mentha arvensis leaves in response to alternaria alternata infection identifies crucial candidates for defense response. | the leaf spot disease of mentha arvensis, caused by alternaria alternata, is a devastating foliar disease worldwide and leads to considerable economic losses. in this investigation, two-dimensional gel electrophoresis (2-de) was used to identify the membrane proteins potentially involved in m. arvensis - a. alternata interaction. membrane proteins, isolated from leaves of control and infected plants, were analyzed by 2-de and identified using mass spectrometry (maldi tof-tof ms/ms). our analysis ... | 2016 | 27177294 |
| [prevalence of sensitization to fungi in patients with respiratory allergy]. | as part of the etiology of respiratory allergy we have genetics, prenatal factors and sensitivity to various airborne allergens, between these fungi are found. relationship has been found between sensitization to fungal in skin tests and allergy pathogenesis and aggravation. there is a few literature in mexico and in the north of the country it is lacking regarding this problem. | 2016 | 27174757 |
| streptomyces zhihengii sp. nov., isolated from rhizospheric soil of psammosilene tunicoides. | an actinomycete strain, designated yim t102(t), was isolated from the rhizospheric soil of psammosilene tunicoides w. c. wu et c. y. wu collected from lijiang, yunnan province, china. the taxonomic position of the new isolate was investigated by a polyphasic approach. phylogenetic analyses based on 16s rrna gene sequences indicated that strain yim t102(t) belongs to the genus streptomyces. strain yim t102(t) was most closely related to streptomyces eurocidicus nrrl b-1676(t) with a pairwise 16s ... | 2016 | 27169711 |
| phytochemical analysis and antifungal activity of extracts from leaves and fruit residues of brazilian savanna plants aiming its use as safe fungicides. | the increasing demand for safe food without preservatives or pesticides residues has encouraged several studies on natural products with antifungal activity and low toxicity. in this study, ethanolic extracts from leaves and fruit residues (peel and seeds) of three brazilian savanna species (acrocomia aculeata, campomanesia adamantium and caryocar brasiliense) were evaluated against phytopathogenic fungi. additionally, the most active extract was chemically characterized by esi-ms and its oral a ... | 2016 | 27169570 |
| antibacterial, antifungal, phytotoxic, antioxidant and hemagglutination activities of organic fractions of arisaema tortuosum. | in the current study, the antimicrobial, phytotoxic, haemagglutination and antioxidant potential of crude methanolic extract (crd. meoh ext.) and four organic fractions of arisaema tortuosum was investigated. all fractions have been screened for antimicrobial properties against eight bacterial pathogens and six fungal pathogens using agar well diffusion and tube dilution method, respectively. furthermore, the organic fractions were also screened for its phytotoxicity against lemna minor. haemagg ... | 2016 | 27166544 |
| fine mapping of the gene for susceptibility to black spot disease in japanese pear (pyrus pyrifolia nakai). | black spot disease, which is caused by the japanese pear pathotype of the filamentous fungus alternaria alternata (fries) keissler, is one of the most harmful diseases in japanese pear cultivation. we mapped a gene for susceptibility to black spot disease in the japanese pear (pyrus pyrifolia nakai) cultivar 'kinchaku' (aki gene) at the top of linkage group 11, similar to the positions of the susceptibility genes ani in 'osa nijisseiki' and ana in 'nansui'. using synteny-based marker enrichment, ... | 2016 | 27162498 |
| comparative genomics of pathogens causing brown spot disease of tobacco: alternaria longipes and alternaria alternata. | the genus alternaria is a group of infectious/contagious pathogenic fungi that not only invade a wide range of crops but also induce severe allergic reactions in a part of the human population. in this study, two strains alternaria longipes cx1 and alternaria alternata cx2 were isolated from different brown spot lesions on infected tobacco leaves. their complete genomes were sequenced, de novo assembled, and comparatively analyzed. phylogenetic analysis revealed that a. longipes cx1 and a. alter ... | 2016 | 27159564 |
| transcriptomic profile of tobacco in response to alternaria longipes and alternaria alternata infections. | tobacco brown spot caused by alternaria fungal species is one of the most damaging diseases, and results in significant yield losses. however, little is known about the systematic response of tobacco to this fungal infection. to fill this knowledge gap, de novo assemblies of tobacco leaf transcriptomes were obtained in cultivars v2 and nc89 after the inoculation of either alternaria longipes (al) or alternaria alternata (aa) at three different time points. we studied the gene expression profile ... | 2016 | 27157477 |
| effect of plant extracts on book deteriorated fungal species. | the aim of the study was to evaluate the effect of leaf extracts of four plants against some isolated fungal species from deteriorated books. aqueous, methanol and chloroform extracts of selected plant species were screened in vitro for their antifungal activity against some book deteriorating fungal species. fifteen species belonging to 09 genera were isolated and identified from infested books in library. aqueous and solvent extracts of leaves of azadiracta indica, callistemon citrinus, eucaly ... | 2016 | 27154063 |
| silencing of sterol glycosyltransferases modulates the withanolide biosynthesis and leads to compromised basal immunity of withania somnifera. | sterol glycosyltransferases (sgts) catalyse transfer of glycon moiety to sterols and their related compounds to produce diverse glyco-conjugates or steryl glycosides with different biological and pharmacological activities. functional studies of sgts from withania somnifera indicated their role in abiotic stresses but details about role under biotic stress are still unknown. here, we have elucidated the function of sgts by silencing sgtl1, sgtl2 and sgtl4 in withania somnifera. down-regulation o ... | 2016 | 27146059 |
| binary and tertiary combination of alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on hepg2 cells: toxic effects and evaluation of degradation products. | fungi producers of mycotoxins are able to synthesize more than one toxin. alternariol (aoh) is one of the mycotoxins produced by several alternaria species, the most common one being alternaria alternata. the toxins 3-acetyl-deoxynivalenol (3-adon) and 15-acetyl-deoxynivalenol (15-adon) are acetylated forms of deoxynivalenol (don) produced by fusarium graminearum. in the present work it is determined and evaluated the toxic effects of binary and tertiary combination treatment of hepg2 cells with ... | 2016 | 27131905 |
| temporal changes in fungal communities from buckwheat seeds and their effects on seed germination and seedling secondary metabolism. | seed-associated fungal communities affect multiple parameters of seed quality at all stages of production, from seed development to post-harvest storage and germination. we therefore investigated the diversity and dynamics of fungal communities in the seeds of common buckwheat (fagopyrum esculentum) and tartary buckwheat (f. tataricum) from harvest to 1 y of storage. fungal populations in seeds were relatively stable, comprised mainly of field fungi. incidence of fungi was most likely determined ... | 2016 | 27109364 |
| volatile compounds emitted by diverse phytopathogenic microorganisms promote plant growth and flowering through cytokinin action. | it is known that volatile emissions from some beneficial rhizosphere microorganisms promote plant growth. here we show that volatile compounds (vcs) emitted by phylogenetically diverse rhizosphere and non-rhizhosphere bacteria and fungi (including plant pathogens and microbes that do not normally interact mutualistically with plants) promote growth and flowering of various plant species, including crops. in arabidopsis plants exposed to vcs emitted by the phytopathogen alternaria alternata, chan ... | 2016 | 27092473 |
| how to diagnose mould allergy? comparison of skin prick tests with specific ige results. | diagnosis of mould allergy is complicated due to the heterogeneity of the test material and the decrease in the number of commercial mould skin test solutions that are currently available. | 2016 | 27027397 |
| inhibition of microorganisms involved in deterioration of an archaeological site by silver nanoparticles produced by a green synthesis method. | the citadel, part of the pre-hispanic city of teotihuacan and listed as a world heritage site, harbors irreplaceable archaeological walls and murals. this city was abandoned by the 7th century and its potential deterioration represents a noteworthy loss of the world's cultural heritage. this research consisted of isolation and identification of bacteria and fungi contributing to this deterioration from walls of a pre-hispanic city. in addition, silver nanoparticles (agnp) produced, using a green ... | 2016 | 27015961 |
| [inhibition of bacillus pumilus ar03 on alternaria alternata and erysiphe cichoracearum on tobacco]. | this study aimed to evaluate the efficiency of bacillus pumilus ar03 against altenaria alternata and erysiphe cichoracearum. the antagonistic activities were studied in the way of co-culture on plate, inhibition of pathogen conidia germination on concave slides and lb agar medium. in the investigation, the water suspension of living cells of strain ar03, at 3 x 10(8) cfu . ml-1 had a remarkable inhibition effect on hyphae growth and conidia germination of a. alternata and caused hyphae deformati ... | 2015 | 26995927 |
| spatial and seasonal influences on culturable endophytic mycobiota associated with different tissues of eugenia jambolana lam. and their antibacterial activity against mdr strains. | present study focuses on diversity and distribution analysis of endophytic fungi associated with different tissues of eugenia jambolana. the influence of season and geographical location on diversity and distribution of endophytic fungi has been analyzed. antibacterial activity of isolated fungal species has also been investigated against mdr bacterial strains. | 2016 | 26988842 |
| triterpenoids from the stems of schisandra grandiflora and their biological activity. | one new ursane-type triterpenoid (1), named granditriol, along with 14 known compounds (2-15), was isolated from the organic extracts of schisandra grandiflora stems. the structure of the new compound was elucidated by extensive spectroscopic methods as 28-norursa-12,17,19,21-tetraen-2α,3α,23-triol. these isolates were evaluated for anti-phytopathogenic fungi activity and cytotoxicity against human cancer cell line (hepg2). asiatic acid (8) and 2α,3α,19α-trihydroxyurs-12-en-28-oic acid (9) inhib ... | 2016 | 26982651 |
| biodegradation of diesel fuel hydrocarbons by mangrove fungi from red sea coast of saudi arabia. | mangrove sediments were collected from major mangrove stands on the red sea coast of saudi arabia. forty five isolates belonging to 12 genera were purified and five isolates as well as their consortium were found to be able to grow in association with petroleum oil as sole carbon source under in vitro conditions. the isolated strains were identified based on internal transcribed spacer (its) rdna sequence analysis. the fungal strains with the greatest potentiality to degrade diesel oil, without ... | 2016 | 26981002 |
| synthesis and antifungal activity of 2h-1,4-benzoxazin-3(4h)-one derivatives. | a series of 2-alkyl-2h-1,4-benzoxazin-3(4h)-ones (4a-l) was easily synthesized by two-step process involving o-alkylation of 2-nitrophenols with methyl 2-bromoalkanoates and next "green" catalytic reductive cyclization of the obtained 2-nitro ester intermediates (3a-l). further, 6,7-dibromo (5a-c) and n-acetyl (6) derivatives were prepared by bromination and acetylation of unsubstituted 2-alkyl-2h-1,4-benzoxazin-3(4h)-ones (4a-c). the novel compounds (3a-l, 4d-l, 5a-c and 6) were fully character ... | 2016 | 26963527 |
| alternaria section alternaria: species, formae speciales or pathotypes? | the cosmopolitan fungal genus alternaria consists of multiple saprophytic and pathogenic species. based on phylogenetic and morphological studies, the genus is currently divided into 26 sections. alternaria sect. alternaria contains most of the small-spored alternaria species with concatenated conidia, including important plant, human and postharvest pathogens. species within sect. alternaria have been mostly described based on morphology and / or host-specificity, yet molecular variation betwee ... | 2015 | 26951037 |
| sesquiterpene emissions from alternaria alternata and fusarium oxysporum: effects of age, nutrient availability, and co-cultivation. | alternaria alternata is one of the most studied fungi to date because of its impact on human life - from plant pathogenicity to allergenicity. however, its sesquiterpene emissions have not been systematically explored. alternaria regularly co-occurs with fusarium fungi, which are common plant pathogens, on withering plants. we analyzed the diversity and determined the absolute quantities of volatile organic compounds (vocs) in the headspace above mycelial cultures of a. alternata and fusarium ox ... | 2016 | 26915756 |
| the importance of mold sensitivity in nonallergic rhinitis patients. | in recent studies, local specific immunoglobulin e (sige) production against allergens in nasal mucosa and a positive response to a nasal allergen provocation test (napt) have been demonstrated in some patients initially diagnosed as nonallergic rhinitis (nar) or idiopathic rhinitis (ir). the aim of this study was to evaluate the presence of local allergic rhinitis (lar) in patients who experience rhinitis symptoms in indoor and outdoor moldy conditions and to investigate the role of the napt in ... | 2016 | 26880361 |
| il-33 mediates reactive eosinophilopoiesis in response to airborne allergen exposure. | exposure to aeroallergens induces eosinophilic airway inflammation in patients with asthma and allergic airway diseases. the circulating number of eosinophils in peripheral blood is relatively small, leading us to hypothesize that bone marrow needs to be engaged quickly to meet the demands of the tissues. | 2016 | 26864308 |
| how the pathogenic fungus alternaria alternata copes with stress via the response regulators ssk1 and sho1. | the tangerine pathotype of alternaria alternata is a necrotrophic fungal pathogen causing brown spot disease on a number of citrus cultivars. to better understand the dynamics of signal regulation leading to oxidative and osmotic stress response and fungal infection on citrus, phenotypic characterization of the yeast ssk1 response regulator homolog was performed. it was determined that ssk1 responds to diverse environmental stimuli and plays a critical role in fungal pathogenesis. experiments to ... | 2016 | 26863027 |
| preclinical experimental and mathematical approaches for assessing effective doses of inhaled drugs, using mometasone to support human dose predictions. | understanding the relationship between dose, lung exposure, and drug efficacy continues to be a challenging aspect of inhaled drug development. an experimental inhalation platform was developed using mometasone furoate to link rodent lung exposure to its in vivo pharmacodynamic (pd) effects. | 2016 | 26859446 |
| ethanolic extract of nigella sativa protects fe(ii) induced lipid peroxidation in rat's brain, kidney and liver homogenates. | the study describes the effect of ethanolic extract of nigella sativa against fe(ii) induced lipid peroxidation. basal and fe(ii) induced thiobarbituric acid reactive species (tbars) production was significantly inhibited by the ethanolic extract of nigella sativa at 25-200 μg/ml. our data revealed that the extract has high dpph radical scavenging activity at highest tested concentrations. the extract significantly chelated fe(ii) and scavenged hydroxyl (oh) radical at 25-200μg/ml concentration. ... | 2016 | 26826815 |
| alternaria alternata allergens: markers of exposure, phylogeny and risk of fungi-induced respiratory allergy. | alternaria alternata spores are considered a well-known biological contaminant and a very common potent aeroallergen source that is found in environmental samples. the most intense exposure to a. alternata allergens is likely to occur outdoors; however, alternaria and other allergenic fungi can colonize in indoor environments and thereby increase the fungal aeroallergen exposure levels. a consequence of human exposure to fungal aeroallergens, sensitization to a. alternata, has been unequivocally ... | 2016 | 26826364 |
| draft genome sequence of alternaria alternata atcc 34957. | we report the draft genome sequence of alternaria alternata atcc 34957. this strain was previously reported to produce alternariol and alternariol monomethyl ether on weathered grain sorghum. the genome was sequenced with pacbio technology and assembled into 27 scaffolds with a total genome size of 33.5 mb. | 2016 | 26769939 |
| influence of environmental parameters on mycotoxin production by alternaria arborescens. | alternaria arborescens has been reported as a common fungal species invading tomatoes and is capable of producing several mycotoxins in infected plants, fruits and in agricultural commodities. alternariol (aoh), alternariol monomethyl ether (ame), and tenuazonic acid (tea) are some of the main alternaria mycotoxins that can be found as contaminants of food. this species can produce these toxic metabolites together with aal toxins (alternaria alternata f. sp. lycopersicum toxins), which can act a ... | 2016 | 26708802 |
| oregano (lippia graveolens) essential oil added within pectin edible coatings prevents fungal decay and increases the antioxidant capacity of treated tomatoes. | tomato is a fruit widely consumed due to its flavor and nutritional value; however, it is susceptible to fungi contamination. oregano essential oil (oeo) is a fungicide whose constituents are volatile; therefore, their incorporation within edible coatings can protect them and maintain their efficacy. in this context, this study evaluated the effect of oeo applied within pectin coatings on the inhibition of alternaria alternata growth, antioxidant content and sensorial acceptability of tomatoes. | 2016 | 26676868 |
| population genetic analysis reveals cryptic sex in the phytopathogenic fungus alternaria alternata. | reproductive mode can impact population genetic dynamics and evolutionary landscape of plant pathogens as well as on disease epidemiology and management. in this study, we monitored the spatial dynamics and mating type idiomorphs in ~700 alternaria alternata isolates sampled from the main potato production areas in china to infer the mating system of potato early blight. consistent with the expectation of asexual species, identical genotypes were recovered from different locations separated by h ... | 2015 | 26666175 |
| microbial transformation of 14-anhydrodigoxigenin by alternaria alternata. | the microbial transformation of 14-anhydrodigoxigenin (1) by alternaria alternata cgmcc 3.577 led to the production of seven new metabolites, 2-8. their structures were determined by extensive spectroscopic (cd, ir, 1d- and 2d-nmr, and hr-esi-ms) data analyses. the reactions in the bioprocess exhibited diversity, including specific oxidation, hydroxylation, reduction, epoxidation, and dehydration. in addition, a hypothetical biocatalytic pathway is proposed. | 2015 | 26663840 |
| evaluation of antifungal efficacy of 0.1% and 0.25% riboflavin with uva: a comparative in vitro study. | antifungal efficacy of photochemical cross-linking (pack-cxl) with 0.1% and 0.25% riboflavin was evaluated with a comparative in vitro study. | 2016 | 26644282 |
| [the influence of b-irradiation on micromycetes isolated from the zone of radionuclide contamination]. | the resistance of the micromycetes to β-irradiation had been studied. the study was conducted on two species: cladosporium sphaerospermum penz. and alternaria alternata (fr.) keissl., each of them was represented by six strains. half of strains were isolated from the inner locations of the "shelter" object (so), which were characterized by different levels of radionuclide contamination. for c. sphaerospermum strains maximum resistance to β-radiation was observed among 20-day-old cultures. the gr ... | 2015 | 26638487 |
| [growth of micromycetes from different ecological niches on agar nutrient media]. | radial growth rate of (k(r)) 153 strains 6 species of micromycetes from different ecological niches was studied on 7 agar media: three standard (malt extract agar, potato-dextrose agar, czapek's agar), and on agar media with plant polymers (carboxymethylcellulose, xylan, soluble starch and apple pectin). endophytic and plant pathogenic strains (biotrophs) of all studied species did not differ significantly in their ability to grow on nutrient media of different composition--average values of k(r ... | 2015 | 26638483 |
| development of a loop-mediated isothermal amplification assay for rapid and specific identification of act producing alternaria alternata, the agent of brown spot disease in tangerine. | rapid, accurate, and easy identification of pathogenic agents has always been important in medicine, veterinary, and agriculture. the brown spot infection is among the most common diseases in tangerine caused by alternaria alternata. due to the existence of seven various pathotypes of a. alternata species, it is challenging and time consuming to detect a pathotype responsible for citrus brown spot. in this study, we were seeking a rapid and specific approach to identify the tangerine pathotype w ... | 2016 | 26638210 |
| detection and quantitative analysis of the non-cytotoxic allo-tenuazonic acid in tomato products by stable isotope dilution hplc-ms/ms. | tenuazonic acid (1) is a mycotoxin produced mainly by fungi of the genus alternaria. it occurs in a variety of agricultural products. allo-tenuazonic acid (2) is an isomer of 1 that is not chromatographically separated from 1 in most analytical methods. therefore, both isomers are quantitated as a sum parameter. in this study a quechers (quick, easy, cheap, effective, rugged and safe) based stable isotope dilution hplc-ms/ms method including the chromatographic separation of both isomers was dev ... | 2015 | 26633086 |
| comparison of component-resolved diagnosis by using allergen microarray with the conventional tests in allergic rhinitis patients: the first using in korea. | the aim of this study was to evaluate the component-resolved diagnosis using a microarray allergen chip (immuno solid-phase allergen chip, immunocap isac) and to compare this new diagnostic tool with the established immunocap methods for allergen-specific ige detection in allergic rhinitis patients. | 2015 | 26622959 |
| influence of the silver nanoparticles on microbial community in different environments. | the aim of this study was to assess the influence of silver nanoparticles (agnps) on the number and diversity of microbial community in different environments (soil extract, water, sewage), and to determine whether the environment inhibits or accelerates the influence of agnps on moulds. agnps (45 ppm) present in the environment decreased bacterial (91%) and fungal (33-85%) numbers, and eliminated some strains, e.g., alternaria alternata and cryptococcus laurentii. based on the biomass growth of ... | 2015 | 26610310 |
| pcr and real-time pcr assays to detect fungi of alternaria alternata species. | fungi of the alternaria genus are mostly associated with allergic diseases. however, with a growing number of immunocompromised patients, these fungi, with a. alternata being the most prevalent one, are increasingly recognized as etiological agents of infections (phaeohyphomycoses) in humans. nowadays, identification of alternaria spp. requires their pure culture and is solely based on morphological criteria. clinically, alternaria infections may be indistinguishable from other fungal diseases. ... | 2015 | 26610309 |
| airway epithelial dual oxidase 1 mediates allergen-induced il-33 secretion and activation of type 2 immune responses. | the il-1 family member il-33 plays a critical role in type 2 innate immune responses to allergens and is an important mediator of allergic asthma. the mechanisms by which allergens provoke epithelial il-33 secretion are still poorly understood. | 2016 | 26597162 |
| interferon and il-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses. | group 2 innate lymphoid cells (ilc2 cells) are type 2 cytokine-producing cells of the innate immune system with important roles in helminth infection and allergic inflammation. here we found that tissue-resident ilc2 cells proliferated in situ without migrating during inflammatory responses. both type i and type ii interferons and interleukin 27 (il-27) suppressed ilc2 function in a manner dependent on the transcription factor stat1. ilc2-mediated lung inflammation was enhanced in the absence of ... | 2016 | 26595888 |
| [screening probiotic endophytic bacteria from medicinal plant flex cornuta and the phytopathogen-inhibiting effect]. | culturable endophytic bacteria were isolated from medicinal plant ilex cornuta by plate-spreading method, strains with strong inhibitory effect on phytopathogen were screened by confrontation culture and fermentation filtrate culture methods, and the morphological changes of phytopathogen hyphae treated with endophytic bacteria were examined by microscopy and micrograph. their phylogenetic relationships were determined by homology analysis of the 16s rdna sequences of pcr products and the taxono ... | 2015 | 26571677 |
| triterpenoids from the herbs of salicornia bigelovii. | a new nortriterpene saponin, 3-o-β-d-glucuronopyranosyl-30-norolean-12,20(29)-dien-23- oxo-28-oic acid, namely bigelovii d (11), was isolated from the hydroalcoholic extract of herbs of salicornia bigelovii along with 10 known saponins (1-10). their chemical structures were identified on the basis of spectroscopic analyses including two-dimensional nmr and a comparison with literature data. some of these compounds showed potent antifungal activities in vitro. compounds 3, 4, 5, 6, 7, 10 and 11 d ... | 2015 | 26569214 |
| the glutathione peroxidase-mediated reactive oxygen species resistance, fungicide sensitivity and cell wall construction in the citrus fungal pathogen alternaria alternata. | the ability to detoxify reactive oxygen species (ros) is critical for pathogenicity in the necrotrophic fungus alternaria alternata. we report a glutathione peroxidase 3 (aagpx3) involved in the complex signalling network that is essential for the detoxification of cellular stresses induced by ros and for a. alternata pathogenesis in citrus. aagpx3 deletion mutants displayed increased sensitivity to h2 o2 and many ros-generating compounds. aagpx3 is required for correct fungal development as the ... | 2016 | 26567914 |
| bioprospecting endophytic fungi and their metabolites from medicinal tree aegle marmelos in western ghats, india. | the increasing emergence of lead drugs for the resistance produced by the pathogenic strains and arrival of new diseases have initiated the need for searching novel metabolites with best anticancer and antimicrobial properties than the existing one. with this view, the investigation was conducted for the isolation, identification, and biological evaluation of potential endophytic fungi of aegle marmelos, a medicinal tree used for more than three decades, for curing various disorders. a total of ... | 2015 | 26539047 |
| ex vivo application of secreted metabolites produced by soil-inhabiting bacillus spp. efficiently controls foliar diseases caused by alternaria spp. | bacterial biological control agents (bcas) are largely used as live products to control plant pathogens. however, due to variable environmental and ecological factors, live bcas usually fail to produce desirable results against foliar pathogens. in this study, we investigated the potential of cell-free culture filtrates of 12 different bacterial bcas isolated from flower beds for controlling foliar diseases caused by alternaria spp. in vitro studies showed that culture filtrates from two isolate ... | 2015 | 26519395 |
| rhamnolipids induce oxidative stress responses in cherry tomato fruit to alternaria alternata. | rhamnolipids showed an antimicrobial activity applicable to a variety of pathogenic microorganisms, but mechanisms were mostly focused on their direct inhibitory effect. | 2016 | 26506951 |
| common airborne fungi induce species-specific effects on upper airway inflammatory and remodelling responses. | whilst the exact cause of chronic rhinosinusitis (crs) remains elusive, it is clear that both inflammation and remodelling are key disease processes. environmental fungi have been linked to airway inflammation in crs; however, their role in the pathogenesis of this condition remains controversial. the current consensus suggests that whilst fungi may not be directly causative, it is likely that crs patients have deficits in their innate and potentially acquired immunity, which in turn may modify ... | 2016 | 26501134 |