Publications

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[characteristics of tularemia vaccinal strains according to laboratory indices]. 195713531836
[biochemical investigations on brucella, pasteurella and pasteurella tularensis]. 195813570377
[comparative investigation on the effect of certain antibiotics on pasteurella tularensis in vitro]. 195813570392
[immunogenic properties of two old tularemia strains; virulent and vaccinal]. 195813605053
[results of microscopic detection of pasteurella tularensis in organs and tissues in guinea pigs]. 195913636338
[tularemia bacteriophage; preliminary communication]. 195913648880
[variability of pasteurella tularensis in various methods of its preservation in laboratory conditions]. 195913648882
[studies on virulence of pasteurella tularensis strains isolated in natural foci of infection]. 195913648885
stability of disseminated aerosols of pasteurella tularensis subjected to simulated solar radiations at various humidities. 195913672905
[on antigenic substances of pasteurella tularensis. immunization of mice with the extracted antigens]. 196013717115
[in vitro phagocytosis of past. tularensis by guinea-pig macrophages. relation between phagocytosis and virulence of the bacteria]. 196013717117
[studies on coagulase and fibrinolysin synthesis by pasteurella tularensis]. 196013723648
[on the virulence of tularemia microbes isolated from the human organism]. 196113726604
antigenic structure of some parvobacteriaceae. 196113732911
[the presence in the serum of the bulgarian turtle testudo graeca of agglutinating pasteurella tularensis]. 196113733589
oxidation of reduced pyridine nucleotides in pasteurella tularensis. i. distribution of diaphorases and transhydrogenases. 196113742274
oxidation of reduced pyridine nucleotides in pasteurella tularensis. ii. separation of diaphorases and transhydrogenases. 196113742275
studies with tularemia vaccines in volunteers. iv. brucella aggiutinins in vaccinated and nonvaccinated volunteers challenged with pasteurella tularensis. 196113746665
[studies on the polysaccharides of pasteurella tularenis. i. isolation of polysaccharides with special reference to their antigenicity]. 196113746939
detection of viability in aged or injured pasteurella tularensis. 196013747759
[studies on antigen preparations from bacterium tularense]. 196013757202
virulence and citrulline ureidase activity of pasteurella tularensis.marchette, nyven j. (university of utah, salt lake city), and paul s. nicholes. virulence and citrulline ureidase activity of pasteurella tularensis. j. bacteriol. 82:26-32. 1961.-the presence of a citrulline ureidase system in pasteurella tularensis strains of high virulence, and its absence in avirulent strains and strains of low virulence was confirmed. the presence of this system, however, was shown to be not directly related to virulence. the only wild strain of p. tularensis tested that la ...196113766500
the cytochrome of pasteurella tularensis. 196113771524
[the inhibiting effect of antibiotics on the multiplication of pasteurella tularensis in tissue culture]. 196013783349
domestic fowl--source of high titer p. tularensis serum for the fluorescent antibody technic. 196013787043
sensitivity in vitro of eighteen strains of pasteurelia tularensis to erythromycin. 196013800534
succinoxidase system of pasteurella tularensis. 196013822116
[research on the pathogenesis of tularemia. i. on the production of the enzyme hyaluronidase by p. tularensis and other bacteria of the genus pasteurella]. 195913831555
attempts at attenuation of bacterium tularense strains. 195913838730
comparison of the properties of virulent strains and attenuated strains b. tularense. 196013838731
[diffusion precipitation on gel of antigens of tularemic bacteria. i]. 196213888882
[variability of the tularemia microbe in natural conditions]. 196213890092
[studies on the sensitivity of some types of tularemia pathogen and pasteurella to antibiotics in vitro]. 196213906159
[action of cortisone on experimental tularemic infection]. 196213913720
clear media for the recovery of pasteurella tularensis.peptic digests of blood and hemoglobin were investigated as substitutes for the blood used in the preparation of glucose-cysteine-blood agar plating medium for the recovery of the virulent schu strain of pasteurella tularensis. digest media so prepared were found to be satisfactory for the quantitative recovery of freshly grown cells but not for cells stored longer than several days. the addition of appropriate quantities of human plasma, bovine sera, or soluble starch rendered the digest media ...196213930117
[modification of a simple blood agar plate for the culture of pasteurella tularensis]. 196213931597
[bacteriological studces on the interference phenomenon with bacterium tularense. ii. further studies on effective conditions]. 196213986714
pyruvate oxidation by pasteurella tularensis strains of graded virulence.weinstein, i. (u.s. army chemical corps, fort detrick, frederick, md.), m. l. guss, and r. a. altenbern. pyruvate oxidation by pasteurella tularensis strains of graded virulence. j. bacteriol. 83:1010-1016. 1962.-the rate of oxidation of sodium pyruvate by pasteurella tularensis was shown to be correlated with the virulence of the strain studied. no qualitative differences in cofactor requirements for or products of pyruvate oxidation were found among strains of graded virulence. the rate of pyr ...196214005758
brain lesions in monkeys infected with pasteurella tularensis. 196314013585
immunodiffusion studies with pasteurella tularensis antigen-rabbit antibody systems. 196214018678
viability and estimation of shelf-life of bacterial populations.mathematical concepts associated with the exponential and probit models are developed, and the similarity of the two methods is discussed. because of its greater flexibility in design, the probit method was used to estimate the shelf-life for four bacterial populations, wet and dry spores of bacillus anthracis and wet and dry cells of pasteurella tularensis. on the basis of data gained by storing these organisms at high temperature, the probit method was used to predict the time at which 50% via ...196214026165
classification of microorganisms by analysis of chemical composition. i. feasibility of utilizing gas chromatography.abel, k. (melpar, inc., falls church, va.), h. deschmertzing, and j. i. peterson. classification of microorganisms by analysis of chemical composition. i. feasibility of utilizing gas chromatography. j. bacteriol. 85:1039-1044. 1963.-the feasibility of utilizing gas chromatography as a sensitive and rapid method for the analysis of lipids as a natural basis for the classification of microorganisms by chemical composition was investigated. the lipids were extracted and transesterified to componen ...196314043992
[dried nutritive agar d for the culture of brucellosis, tularemia and diphtheria pathogens]. 196314071133
[lipolytic activity of several pathogenic microbes]. 196314077131
serologic properties of bentonite particles coated with microbial polysaccharides. 196314101233
a mobile laboratory unit for exposure of animals and human volunteers to bacterial and viral aerosols. 196414117686
[respiration of pasteurella tularensis in the presence of some sugars and alcohols]. 196314120925
investigations on respiration of p.tularensis strains of different virulence, in the presence of some aminoacids. 196314124848
effects of selected cytotoxic agents on antibody production in man; a prelimary report. 196414125985
comparative studies of francisella tularensis and francisella novicida.owen, c. r. (u.s. public health service, rocky mountain laboratory, hamilton, mont.), e. o. buker, w. l. jellison, d. b. lackman, and j. f. bell. comparative studies of francisella tularensis and francisella novicida. j. bacteriol. 87:676-683. 1964.-comparative studies of various properties of francisella tularensis (= pasteurella tularensis) and f. novicida were performed. the two organisms are very similar morphologically. growth of both was markedly enhanced by addition of cystine to media, b ...196414127585
[use of the luminescent-serological method for the detection of the microbe of tularemia]. 196414138436
phagocytosis and intracellular fate of pasteurella tularensis. i. in vitro studies with rabbit peritoneal mononuclear phagocytes. 196414140999
the effect of 6-mercaptopurine on immune response in man. 196414148223
[comparative study of virulent and vaccinal strains of f. tularensis in human embryonal tissue culture]. 196314151791
[research on the antigenic properties of tularin]. 196314165843
tolerance induction and skin graft prolongation by competing antigens. 196414174744
pathogenesis of experimental respiratory tularemia in monkeys. 196414183401
[apropos of the geographic variability of the pathogen of tularemia]. 196414187969
[apropos of the possibility of the penetration of pathogen of tularemia through uninjured skin (preliminary report)]. 196414187972
[experimental study of transmission and harboring of the tularemia microbe by mites (gamasidae)]. 196414197229
[the effect of chlortetracycline on the resting cells of tularemia microbes]. 196414198681
a factor required for growth initiation of pasteurella tularensis. 196414204100
cellular immunity of rats to tularemia. 196414206896
immunogenic substances in culture filtrates and lysates of pasteurella tularensis.hatch, melvin t. (university of utah, salt lake city), and paul s. nicholes. immunogenic substances in culture filtrates and lysates of pasteurella tularensis. j. bacteriol. 88:566-573. 1964.-culture filtrates and lysates of pasteurella tularensis were tested for immunogenicity in mice subsequently infected with either strain 425 or 425 f4g. the efficacy of the vaccines varied with dosage and was significantly dependent upon methods of preparation. the optimal procedures for the production of an ...196414208489
[immune response of the newborn mouse to the injection of microbial antigens. i. production of antibodies against p. tularensis]. 196414210593
[immune response of the newborn mouse to the injection of microbial antigens. ii. obtaining of resistance to infection: experiments with p. tularensis]. 196414210595
phagocytosis and intracellular fate of pasteurella tularensis. ii. in vitro studies with rabbit alveolar and guinea pig alveolar and peritoneal mononuclear phagocytes. 196414219070
blood-free medium for the rapid growth of pasteurella tularensis.a medium composed of (in g/100 ml) tryptose broth with thiamine (difco), 2.6; cysteine-hcl, 0.12; glucose, 1; feso(4), 7h(2)o, 0.005; kcl, 0.02; histidine, 0.1; tris(hydroxymethyl)aminomethane (tris) buffer, 0.3; and agar, 1; will support rapid growth of the fully virulent schu-s4 strain of pasteurella tularensis. although the test organism grew rapidly on medium from which kcl and tris buffer were omitted, these two components increased the stability of the medium upon storage at 4 c. it was ne ...196414239582
medium for the quantitative recovery of members of the genera pasteurella and brucella.a modification of peptic digest-starch (pds) medium for the quantitative enumeration of pasteurella tularensis is described. this modification (pdm), in which the concentration of l-cysteine was decreased and in which brilliant green was substituted for the penicillin added to the original medium, was evaluated and was found satisfactory for the recovery of p. tularensis, p. pestis, and members of the genus brucella, from freshly harvested and stored cultures as well as aerosolized organisms pro ...196414239584
results of a five-year survey for certain enzootic diseases in the fauna of western utah. 196514248984
comparison of two techniques to study in vitro uptake and fate of pasteurella tularensis. 196414267334
[studies on the sensitivity to antibiotics of f. tularensis cultures isolated in the stavropol region]. 196414319182
evaluation of live tularemia vaccine prepared in a chemically defined medium.a chemically defined medium was prepared which adequately supported growth of a vaccine strain of pasteurella tularensis. this medium differed from those previously described in: (i) concentration of components, (ii) a requirement for calcium pantothenate to obtain increased growth, and (iii) a low initial ph. varying the concentration of individual components up to 10 times the standard amount did not increase the viable population or affect dissociation. the vaccine strain grown in this chemic ...196514325885
fluorescent antibody demonstration of pasteurella tularensis. 196514332139
use of the immunofluorescence method in an epidemic focus of tularaemia. 196514332140
[atypical lang's tularemia strains]. 195414349255
[demonstration of an incomplete l cycle in pasteurella tularensis]. 195414352530
a new organism resembling p. tularensis isolated from water. 195514357545
studies on bacterium tularense antigens. i. the isolation, purification, and biologic activity of antigen preparations from bacterium tularense. 195514367822
studies on bacterium tularense antigens. ii. chemical and physical characteristics of protective antigen preparations. 195514367823
[modification of agglutination properties of culture of pasteurella tularensis following exposure to various degrees of heat]. 195514387226
oxidation of glutamic acid by pasteurella tularensis. 195514392122
[the antigenicity of glycolipoproteins and lipopolysaccharides from tularemia bacteria. part ii. antibody production after intracutaneous injections in men]. 195914410197
homogeneity of response of mouse and guinea pig strains to virulence tests with bacillus anthracis and pasteurella tularensis. 195914417035
comparative study of strains of b. tularense in the old and new world and their taxonomy. 195914428832
[immunization of mice against pasteurella tularensis. comparison of immunizing properties of live and killed bacilli from a virulent strain]. 196114450296
[in vitro phagocytosis of pasteurella tularensis by guinea pig macrophages. effects of immunity on the phagocytic activity of the macrophages]. 196214450297
[in vitro phagocytosis of pasteurella tularensis by guinea pig macrophages. variations in phagocytic responses of macrophages dependent upon the nature of the irritants used]. 196214450298
detection of air-borne pasteurella tularensis using the fluorescent antibody technique.considerable research has been directed toward the development of rapid methods for the identification of air-borne microorganisms. the application of the fluorescent antibody technique (fat) coupled with the impaction of contaminated air onto glass slides affords a rapid and specific method for the identification of air-borne pasteurella tularensis. early experiments presented problems of cross-reaction with organisms other than p. tularensis. these cross-reactions are eliminated by specific ad ...196114450856
further studies of strains of tularaemic bacteria of the old and new world. 196214481959
lack of demonstrable enhancement of virulence of francisella tularensis during animal passage. 196114482893
[further studies on the antigenic structure of brucella brucei and pasteurella tularensis]. 196214483990
[on the transovarian transmission of the tularemia pathogen in ticks dermacentor marginatus sulz]. 196214485933
isolation of pasteurella tularensis in a community hospital. 196214490567
[bacteriological studies on the interference phenomenn with bacterium tularense. i. experiments with guineapigs and rabbits]. 196214497415
an attenuated strain of the facultative intracellular bacterium francisella tularensis can escape the phagosome of monocytic cells.the facultative intracellular bacterium francisella tularensis is a highly virulent and contagious organism, and little is known about its intracellular survival mechanisms. we studied the intracellular localization of the attenuated human vaccine strain, f. tularensis lvs, in adherent mouse peritoneal cells, in mouse macrophage-like cell line j774a.1, and in human macrophage cell line thp-1. confocal microscopy of infected j774a.1 cells indicated that during the first hour of infection the bact ...200314500514
tularemia.tularemia is a complex clinical disorder caused by the ubiquitous intracellular parasite francisella tularensis, which has many mammalian and insect hosts. the peak observed incidence of tularemia occurred in 1939, and most present-day clinicians have never seen a case of this disease. tularemia manifests several different clinical syndromes, depending on the portal of entry. f. tularensis has been used in biological warfare experimentation and it has been weaponized and stockpiled in the past b ...200314505277
molecular diagnostic techniques for use in response to bioterrorism.the use of micro-organisms as agents of biological warfare is considered inevitable for several reasons, including ease of production and dispersion, delayed onset of symptoms, ability to cause high rates of morbidity and mortality and difficulty in diagnosis. therefore, the clinical presentation and pathogenesis of the organisms posing the highest threat (variola major, bacillus anthracis, yersinia pestis, clostridium botulinum toxin, francisella tularensis, filoviruses, arenaviruses and brucel ...200314510181
myositis and septicaemia caused by francisella tularensis biovar holarctica.a case of tularaemia presenting with severe septicaemia and myositis is reported. the infection was presumed to be acquired by a bite from the horse fly haematopota pluvialis, also known as the rain fly.200314514156
infectious diseases. an obscure weapon of the cold war edges into the limelight. 200314551418
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