alcohol-related birth defects: an update. | historically, mankind has at least suspected that alcohol was somehow connected with undesirable effects on progeny. in the 18th century, physicians became aware that maternal alcohol consumption resulted in excess fetal and neonatal mortality, low birth weight, and many other deleterious effects. perhaps as a response to the temperance and prohibition periods, scientists lost sight of or interest in the effects of alcohol in pregnancy. in the late 1960s and early 1970s, the issue surfaced again ... | 2011 | 3141958 |
the need to compare the effectiveness of antidepressant drugs: in which patient populations? | | 2011 | 3167485 |
pattern reversal visual evoked potentials in phenylketonuria. | the pathogenesis of brain dysfunction in phenylketonuria (pku) is still under investigation. hyperphenylalaninaemia results in increased turnover of myelin. in order to demonstrate the derangement of myelinization in pku we studied the visual evoked potentials (vep) in 14 pku patients and in 20 normal subjects. vep findings were correlated with the metabolic control of the disease and with the electroencephalographic findings. vep were more sensitive than the eeg in detecting a neurological dysf ... | 2011 | 3149700 |
coagulation, inflammation, and responses to injury. | several mechanisms contributing to the development of post-traumatic alterations in organ function are reviewed. the importance of interactions between clotting and inflammatory mediators is detailed. a discussion of management strategies emphasizes the role of early recognition and aggressive treatment of organ dysfunction. | 2011 | 3146417 |
problems assessed but far from resolved in 1988. | | 2011 | 3143657 |
vitamin d metabolite profiles in moderate renal insufficiency of childhood. | in a prior study, we reported vitamin d metabolite profiles in the plasma of healthy children. in view of these findings, we investigated these same profiles in children with moderate renal insufficiency. specimens were obtained in both summer and winter in untreated patients, and before and after treatment for up to 1 year, with either 25(oh)d3 or 1,25(oh)2d3. mean pretreatment 1,25(oh)2d levels were normal. levels of 25(oh)d3 were also normal and continued to vary with season. mean pretreatmen ... | 2011 | 3153059 |
doppler studies in the growth retarded fetus and prediction of neonatal necrotising enterocolitis, haemorrhage, and neonatal morbidity. | in 82 consecutive cases of intrauterine growth retardation managed by established criteria fetal doppler studies identified 29 fetuses with absence of end diastolic frequencies in the fetal aorta. these same fetuses were significantly more growth retarded (p less than 0.001) and had an earlier gestational age at delivery (p less than 0.001) than those with end diastolic frequencies present. a subgroup of these cases was analysed in more detail to examine the prognostic value of this phenomenon f ... | 2011 | 3101778 |
complications of renal transplantation. | | 2011 | 4281487 |
skeletal remodelling in the temporomandibular joint after oblique sliding osteotomy of the mandibular rami. | skeletal remodelling of the temporomandibular joints took place in 80% of cases after oblique sliding osteotomies of the rami. the new bone formation was found in both the condylar and temporal parts of the joint. it was mostly located on the posterior surface of the condyle and in the roof of the temporal part of the joint. no differences in skeletal remodelling were found between wiring and nonwiring cases. | 2011 | 3088149 |
induction of indoleamine dioxygenase by interferon in mice: a study with different recombinant interferons and various cytokines. | since it is important the availability of a specific marker for interferon induction in vivo, we investigated the effect of different recombinant interferons and various cytokines on indoleamine 2,3-dioxygenase activity. although with different magnitude, recombinant interferon-alpha a/d (bgl ii) hybrid, interferon-gamma and tumor necrosis factor, all increase the activity of this enzyme, whereas interleukin-1, recombinant interferon-alpha a and interferon-alpha d do not induce this activity in ... | 2011 | 3128977 |
factors influencing the accumulation of sediment-sorbed hexachlorobiphenyl by midge larvae. | | 2011 | 3125867 |
[substantiation of permissible migration quantities of beryllium in sanitary-chemical studies of materials designated for contact with food products]. | | 2011 | 3060413 |
measurement of l-[1-14c]leucine kinetics in splanchnic and leg tissues in humans. effect of amino acid infusion. | although whole-body leucine flux is widely measured to study body protein turnover in humans, the contribution of specific tissues to the total-body measurement remains unknown. by combining the organ-balance technique with the systemic infusion of l-[1-14c]leucine, we quantitated leucine production and disposal by splanchnic and leg tissues and by the whole body, simultaneously, in six normal men before and during amino acid infusion. at steady state, disposal of arterial leucine by splanchnic ... | 2011 | 3046968 |
vagal innervation techniques in the treatment of panic disorder. | | 2011 | 3056393 |
[this is how parents can feel--donna is coming home with us! wait, you can't just do that!]. | | 2011 | 3131909 |
[phase ii study of carboplatin in cervical carcinoma]. | a phase ii multi-center study of carboplatin for cervical carcinoma was carried out in 22 institutes throughout japan. the patients registered consisted of 40 women with 39 cervical carcinomas and an endometrial carcinoma, of whom 31 were evaluable. carboplatin was administered intravenously every 4 weeks at a dose of 400 mg/m2, in cases with no prior therapies and/or p.s. 0-1, and 300 mg/m2 in cases with prior therapies and/or p.s. 2-3. the overall response rate of 31 evaluable cases was 19.4% ... | 2011 | 3056277 |
origin of dreams: anticipation of modern theories in the philosophy and physiology of the eighteenth and nineteenth centuries. | | 2012 | 3532158 |
chaperones during genital examinations: theory to practice. | | 2012 | 3578176 |
chaperones during genital examinations: theory to practice. | | 2012 | 3578176 |
strictures of the bile ducts. | | 2012 | 4180267 |
strictures of the bile ducts. | | 2012 | 4180267 |
[advances in the diagnosis and treatment of pulmonary embolism]. | | 2012 | 3601774 |
[rubinstein-taybi syndrome with multiple keloids]. | the authors report an unusual case of rubinstein-taybi syndrome, in which alterations such as blepharoptosis, unilateral microphthalmia, bilateral and inferior iris, lens, and choroidal colobomas and unilateral optic nerve pit are present in addition to apparently spontaneous multiple keloids. a histopathological study of the skin and a culture of fibroblasts have pointed out a reduction of the cell duplication time. | 2012 | 3571836 |
[controlled clinical trials]. | | 2012 | 3561576 |
[controlled clinical trials]. | | 2012 | 3561576 |
dysrhythmias after direct-current cardioversion. | the success rate of direct-current (dc) countershocks and postshock arrhythmias are of concern for the design of automatic devices. results of 112 dc shocks for induced ventricular tachycardia/fibrillation (vt/vf) (n = 99) or atrial fibrillation (af) were analyzed. clinical and arrhythmia characteristics were related to the success rate of dc shocks as well as postshock arrhythmias. sixty-one patients were men and 14 were women; mean age was 52 +/- 15 years. coronary artery disease was present i ... | 2012 | 3510522 |
effects on hearing during prolonged oral contraceptive use. | different hearing defects have been attributed to prolonged use of oral contraceptives. the aim of the present investigation has been the evaluation by means of a number of audiological tests and of brain-stem evoked responses (bser) of the possible incidence of subclinical pathology of the nervous hearing structures in these subjects. twenty healthy subjects taking oral contraceptives from 9 to 30 months and 10 paired controls have been studied. no hearing loss was found but the study of bser s ... | 2012 | 3568658 |
effect of female odour on male hamsters mediated by the vomeronasal organ. | a comparison was made of the response to female vaginal odour, between males that were intact (i), had an ablated vomeronasal epithelium (vnox) or had the main olfactory epithelium destroyed by zinc sulphate lavage (zn). i males, after exposure to vaginal odour, can subsequently discriminate between the donor of the odour and other, mismatching females. vnox males are unable to discriminate. peripherally anosmic males (zn) could still discriminate mismatching females. neither treatment affected ... | 2012 | 4070382 |
effect of female odour on male hamsters mediated by the vomeronasal organ. | a comparison was made of the response to female vaginal odour, between males that were intact (i), had an ablated vomeronasal epithelium (vnox) or had the main olfactory epithelium destroyed by zinc sulphate lavage (zn). i males, after exposure to vaginal odour, can subsequently discriminate between the donor of the odour and other, mismatching females. vnox males are unable to discriminate. peripherally anosmic males (zn) could still discriminate mismatching females. neither treatment affected ... | 2012 | 4070382 |
childhood primary cutaneous non-t/non-b lymphoma followed by acute t-cell leukemia. | an 8-year-old girl presented with cutaneous lymphoma without bone marrow or visceral involvement. the tumor cells displayed convoluted and invaginated euchromatic nuclei. the immunophenotype of these cells was non-t/non-b (ia+, calla-, sig-, tdt-, e-, thy-). the skin lesions regressed promptly with chemotherapy including cyclophosphamide, vincristine, methotrexate, doxorubicin, and cytosine arabinoside. six months after the completion of chemotherapy (18 months postdiagnosis), the patient had a ... | 2012 | 3486034 |
puva for cutaneous t-cell lymphoma. 10 years after. | | 2012 | 3485032 |
[observation on the subject of domestic parasites]. | | 2012 | 3504141 |
extended modified postauricular incision of the temporomandibular joint. | the traditional postauricular approach to the temporomandibular joint has excellent cosmetic results since the entire incision is concealed in the postauricular flexure. excellent posterior joint exposure, good lateral joint exposure, and fair anterior joint exposure are obtained. the risk of injury to the facial nerve is decreased. an extended modification of the postauricular incision was developed to overcome some of the disadvantages of the postauricular incision while maintaining its advant ... | 2012 | 3468462 |
[tumors of the bladder and peroperative genitourinary ultrasonography. a proposal for echographic classification]. | | 2012 | 3524151 |
[hypertension in children]. | | 2012 | 4893774 |
airway smooth muscle and disease workshop. october 24-26, 1986, rotherwick, hants., u.k. proceedings. | | 2012 | 3662247 |
"cost containment" in the management of hypertension. | | 2012 | 3592424 |
"cost containment" in the management of hypertension. | | 2012 | 3592424 |
[arthroscopy of degenerative lesions of the internal meniscus. classification and treatment]. | in reference to 310 degenerative meniscal lesions (dml), we are proposing to classify these lesions into five types. they must be differentiated from arthrosis to which they are not automatically associated, even if the presence of cartilaginous lesions appears to be an important prognostic factor. likewise, studies by age groups mix pure traumatic lesions and properly so called dmls (which, by definition, do not involve a true initial trauma); the role of micro-traumas seems however probable. i ... | 2012 | 3602906 |
[functions of the masticatory muscle characterized by muscle microvibration. 2. muscle microvibration during relaxation and contraction of the masseter and anterior temporal muscles]. | | 2012 | 3467182 |
[diagnosis and treatment of the initial stage of alcoholism]. | | 2012 | 3666170 |
[diagnosis and treatment of the initial stage of alcoholism]. | | 2012 | 3666170 |
adenosine deaminase in the acquired immunodeficiency syndrome. | | 2012 | 3416480 |
nature of polymorphism in hla-a, -b, and -c molecules. | diversity in 39 hla-a, -b, and -c molecules is derived from 20 amino acid positions of high variability and 71 positions of low variability. variation in the structurally homologous alpha 1 and alpha 2 domains is distinct and may correlate with partial segregation of peptide and t-cell receptor binding functions. comparison of 15 hla-a with 20 hla-b molecules reveals considerable locus-specific character, due primarily to differences at polymorphic residues. the results indicate that genetic exc ... | 2012 | 3375250 |
care of the terminally ill includes the family. | | 2012 | 3370606 |
mucocele of the skull. | | 2012 | 3349717 |
central nervous system lesions and advanced ovarian cancer. | over the past 5 years we have seen seven cases of central nervous system tumors in patients with advanced or recurrent ovarian carcinoma. these have ranged in location from the conus medullaris to the brain and have varied in time of occurrence from the time of cancer diagnosis to 63 months following surgery. a diagnosis of metastatic ovarian carcinoma was established in six of the cases, while one patient had a second primary malignancy. all cases had prodromal and localizing neurologic symptom ... | 2012 | 3366397 |
enhancement of cytogenetic damage and of antineoplastic effect by caffeine in ehrlich ascites tumor cells treated with cyclophosphamide in vivo. | enhanced cytogenetic damage by cyclophosphamide (cp) was observed when ehrlich ascites tumor cells were exposed in vivo to nontoxic concentrations of caffeine. one h before i.p. injection of 5-bromodeoxyuridine adsorbed to activated charcoal ehrlich ascites tumor-bearing mice treated i.p. with cp appear to have a dose-dependent increase in sister chromatid exchange rates and cell division delays. caffeine increased the survival time of the ehrlich ascites tumor-bearing mice treated with cp and m ... | 2012 | 3342394 |
a study comparing transcervical with transabdominal chorionic villus sampling (cvs). | chorionic villus sampling (cvs) was performed in 50 anaesthetized patients before therapeutic abortion by the transabdominal route and then by the transcervical route. the two methods of villus sampling were equally successful in obtaining villi but the transcervical method was significantly better at obtaining chorionic villi greater than 10 mg in weight (chi 2 13.92 p less than 0.001). placental position did not affect villus recovery with either sampling method. | 2012 | 3342211 |
[transabdominal electronic sector scanning of the prostate]. | | 2012 | 3903306 |
u.s.-japan cooperation. | | 2012 | 3336785 |
[look for a career in psychiatry, you too!. interview by kjell arne bakke]. | | 2012 | 3376002 |
exploring the vitamin myth. | | 2012 | 3460126 |
[generalized tendomyopathy: psychological profile of a patient group in the course of integrated treatment]. | 27 patients suffering from fibrositis were studied using a series of psychological tests in the course of an integrated group treatment program. in addition, their behaviour in the treatment program was observed and information about their behaviour in interpersonal conflicts was gathered. the results confirmed earlier observations that these patients show similar patterns in a projective test (rosenzweig picture frustration test) as patients with other rheumatic or other psychosomatic affection ... | 2012 | 3326356 |
[comparison of permanent cardiac pacing and cardiac pacing on demand in mixed carotid sinus syndrome. acute- and medium-term follow-up study]. | the aim of the study was to evaluate the importance of atrial synchronism for pacing therapy of patients with mixed carotid sinus syndrome. on 23 patients (21 m, 2 f; mean age 69 +/- 8 years) affected by symptomatic mixed carotid sinus syndrome we performed: 1) the study of ventriculo-atrial conduction, 2) the evaluation of pacemaker effect and 3) the carotid sinus massage in standing position during vvi and dvi temporary pacing. all patients received a permanent dvi pacemaker and then underwent ... | 2012 | 3384245 |
[sealing of woven and knitted materials used in cardiac surgery by means of electrically activated blood]. | | 2012 | 3616771 |
epidermal cysts of the eyelid. | | 2012 | 3341987 |
psychogenic habit cough: review and case reports. | psychogenic habit cough--a condition that can be debilitating if it extends over a period of years--has been described in both pediatric and adolescent populations, but not in adults. the authors review the cases of 4 adult patients with this condition, review the available pediatric/adolescent literature, and make suggestions for the direction of future research. in some cases, psychogenic habit cough in adults can be successfully treated with a combination of psychotherapy, relaxation therapy, ... | 2012 | 3320033 |
[steroidogenesis in ovarian tumors]. | | 2012 | 3311390 |
commerce or con: young people and cigarette advertising. | | 2012 | 3370949 |
richard bright, pioneer epileptologist. | | 2012 | 3281059 |
[myocardial puncture by a central venous catheter introduced across the vena basilica]. | | 2012 | 3589090 |
[myocardial puncture by a central venous catheter introduced across the vena basilica]. | | 2012 | 3589090 |
[migration of a thoracic epidural catheter]. | | 2012 | 3589091 |
[migration of a thoracic epidural catheter]. | | 2012 | 3589091 |
the structure of te(oh)6.na3p3o9.k3p3o9. | the structure of this compound, originally described in space group c2/c [averbuch-pouchot & durif (1987). acta cryst. c43, 1653-1655] is properly described as rhombohedral, space group r3c, with a = 12.355 (4) a, a = 51.01 (2) degrees, z = 2. (hexagonal cell: a = 10.640 (4), c = 32.16 (2) a, z = 6). revised coordinates are given. | 2012 | 3271075 |
structure of 6-dodecyl-2-methoxy-1,4-benzoquinone, a new synthetic contact allergen. | c19h30o3, mr = 306.45, triclinic, p-1, a = 5.453 (1), b = 5.608 (1), c = 30.129 (2) a, alpha = 85.85 (1), beta = 88.66 (1), gamma = 83.02 (1) degree, v = 912.0 (1) a3, z = 2, dx = 1.116 mg m-3, cu k alpha radiation, lambda = 1.5418 a, mu = 0.548 mm-1, f(000) = 336, t = 296 k, r is 0.040 for 2489 observed unique reflections. the aliphatic side chain is slightly rotated from the quinone ring. the angle between the quinone-ring plane and the mean dodecyl-chain plane is 20.8 (2) degrees. the average ... | 2012 | 3271072 |
prediction of p-center location from the distribution of energy in the amplitude envelope: ii. | | 2012 | 3340507 |
[neurinoma of the cecum]. | | 2013 | 3951146 |
[neurinoma of the cecum]. | | 2013 | 3951146 |
development of a dental health test for adolescents. | | 2013 | 3870263 |
thermographic assessment of healed burn wounds. | | 2013 | 3843671 |
russell-silver syndrome and hypopituitarism. patient report and literature review. | russell-silver syndrome (rss) is a sporadic form of prenatal onset dwarfism with typical facial features, variable asymmetry, and linear growth 3 to 4 sds below the mean. endocrinologic studies are usually normal; however, six cases of rss with growth hormone deficiency have been reported, three of which had additional pituitary abnormalities. we describe another case, a 7-year-old girl with rss and deficiencies of growth hormone, corticotropin, and thyroid-stimulating hormone. replacement thera ... | 2013 | 3946325 |
occupational risks for meningiomas of the cns in sweden. | using the cancer-environment registry of sweden, which links cancer incidence (1961 to 1979) with census information (1960) for all employed individuals in sweden, a systematic, population-based assessment was made of the occurrence of meningiomas of the cns according to industrial and occupational classifications. statistically significant standardized incidence ratios (sir) between 5 and 6 for meningioma were observed among glass, porcelain, or ceramic workers of both sexes. sirs of similar ma ... | 2013 | 3819887 |
extracranial arterial reconstruction for chronic cerebral ischaemia. an audit of experience in the durban teaching hospitals. | experience with 147 operations for extracranial cerebral arterial reconstruction in 122 patients over a 36-month period is presented. the commonest condition in white, black and indian patients was atherosclerosis, although 8 of the 23 black patients had nonspecific aorto-arteritis (takayasu's disease). operations within the mediastinum included bypass from the ascending aorta to major arterial branches (14), brachiocephalic endarterectomy (1), and replacement grafts of carotid (1) and subclavia ... | 2013 | 3787377 |
[value of intrauterine contraception]. | the rate of iud complications has been reduced by the development of iuds made out of copper and by the improvement of their shape. the number of women using iuds has increased steadily over the last 10 years. the negative aspects are circulatory problems, discharges, undesired pregnancies, and infection of the genitalia. the improved copper iud can remain effective for up to 7 years. there has been no correlation shown between the use of the iud and cancer of the endometrium or cervix. for iud ... | 2013 | 4049935 |
[value of intrauterine contraception]. | the rate of iud complications has been reduced by the development of iuds made out of copper and by the improvement of their shape. the number of women using iuds has increased steadily over the last 10 years. the negative aspects are circulatory problems, discharges, undesired pregnancies, and infection of the genitalia. the improved copper iud can remain effective for up to 7 years. there has been no correlation shown between the use of the iud and cancer of the endometrium or cervix. for iud ... | 2013 | 4049935 |
[characteristic behavior patterns of chronic schizophrenics during play therapy with ball passing]. | | 2013 | 4875565 |
[characteristic behavior patterns of chronic schizophrenics during play therapy with ball passing]. | | 2013 | 4875565 |
epidermoid carcinoma of the conjunctiva. | | 2013 | 3772137 |
blood volume, erythrokinetics and spleen function in thrombocythaemia. | essential thrombocythaemia was diagnosed in a series of 18 patients on the basis of platelet counts greater than 1,000 x 10(9)/1. radionuclide studies have been carried out to distinguish thrombocythaemia as a primary disease from polycythaemia vera, myelofibrosis and chronic granulocytic leukaemia presenting with high platelet counts. these have included blood volume and spleen function, and radio-iron (52fe) has been used to demonstrate the presence of extramedullary (splenic) erythropoiesis. ... | 2013 | 3933244 |
the relationship of clinical allergy and the chemical contamination of food. | | 2013 | 3759815 |
[topical aspects of professional medical morals]. | | 2013 | 3750030 |
address of the president. | | 2013 | 3866016 |
pain in the orbit: a feature of dural tap. | | 2013 | 3728920 |
postmenopausal estrogens in prevention of osteoporosis. benefit virtually without risk if cardiovascular effects are considered. | postmenopausal estrogens can delay or prevent osteoporosis and decrease the frequency of fractures, but they also increase the risk of endometrial cancer. a decision analytic model was developed using a markov process with 18 different states to estimate quality-adjusted life expectancy with and without estrogen therapy. the model considered fractures of the hip, wrist, pelvis, humerus and spine with potential outcomes of short-term morbidity, long-term disability, nursing home placement, and de ... | 2013 | 3728509 |
[physiological parameters in simulated acute and chronic hypoxia]. | | 2013 | 3790303 |
halothane hepatitis in children. | | 2013 | 3728924 |
quantitation of cellular resolution in situ hybridization histochemistry in brain by image analysis. | a new method for relative quantitation of mrna levels with single neuron resolution is described. hybridized tissue sections are emulsion dipped, exposed, and developed. the resulting silver grains are visualized using dark-field microscopy at high magnification. the method relies on computer-based image analysis of sequentially located, high resolution, small fields containing the cell images, each of which is analyzed for mrna content. maps of cell distributions are constructed, with cell mark ... | 2013 | 3696504 |
noninteraction of digoxin and nifedipine in cardiac patients. | | 2013 | 3700685 |
[extrahepatic bile duct carcinoma]. | | 2013 | 3660370 |
[distribution and clinical significance of lymphocyte subsets in patients with chronic aplastic anemia]. | | 2013 | 3652827 |
regional arterial chemotherapy of liver tumours. i. performance comparison between a totally implantable pump and a conventional access system. | thirty-nine patients with liver tumours have been submitted to regional arterial chemotherapy by means of either totally implantable infusaid-400 pumps (22 c.) or implantable ports (17 c.). the latter were subsequently perfused with external pumps. there was one single major operative complication and no operative deaths. most patients underwent continuous fudr infusion. access related complications occurred in both groups. treatment was stopped for access related complications in 18.4% and 29.4 ... | 2013 | 3758367 |
[work time balance]. | | 2013 | 3640470 |
an approach to digital signal processing for ultrasonics research. | the increasingly sophisticated techniques for the extraction of information from ultrasonic data entail a corresponding increase in complexity of the software used. an interactive signal and image processing package, called twodimsy, has been developed at the ultrasonics institute to allow non-programmers an entry to digital signal processing, and to simplify the task of staff involved in programming. we present an outline of the design considerations which shaped twodimsy, and a brief history o ... | 2013 | 3617236 |
[prenatal diagnosis of hemophilia a by dna analysis. first experience in spain]. | | 2013 | 3613722 |
myocardial localization of technetium-99m mdp in an infant. | | 2013 | 3698441 |
[effect of smoking on pregnancy]. | | 2013 | 3623251 |
ibuprofen does not affect fibrinolytic activity. | | 2013 | 3664167 |
the erectile angle: objective criterion to evaluate the papaverine test in impotence. | intracavernous papaverine injection may be the first diagnostic step in the assessment of the impotent patient. however, the appreciation of its effect must rely on the evaluation of penile rigidity. since measurement of rigidity requires a sophisticated procedure that may not be available to the majority of practitioners, we attempted to find a simple and objective method to evaluate the results of this common test. we tested 50 patients complaining of impotence with intracavernous injection of ... | 2013 | 3669162 |