| susceptibilities to clarithromycin and erythromycin of isolates of chlamydia pneumoniae from children with pneumonia. | we tested in vitro 49 isolates of chlamydia pneumoniae obtained from 35 children with community-acquired pneumonia against clarithromycin and erythromycin. the children were part of a treatment study comparing the two drugs. clarithromycin was 2- to 10-fold more active than erythromycin, with a mic for 90% of strains tested and minimal chlamydiacidal concentration for 90% of strains tested of 0.031 microgram/ml compared with 0.125 microgram/ml for erythromycin. eight of these children, two of wh ... | 1994 | 7979292 |
| age specific prevalence of antibodies against chlamydia pneumoniae in iceland. | chlamydia pneumoniae is a newly recognized common cause of respiratory tract infections. the aim of this study was to examine its prevalence in iceland. the study was based on 1020 serum samples from individuals 0-99 years old. the samples were divided into 10-year age groups. igg and igm antibodies were determined with microimmunofluorescence assay. an igg titer > or = 32 and igm titer > or = 16 were considered positive. the prevalence of positive igg titer in the study population was 53 +/- 16 ... | 1994 | 7984969 |
| protective effects of sparfloxacin in experimental pneumonia caused by chlamydia pneumoniae in leukopenic mice. | the in vivo antichlamydial activities of sparfloxacin and reference drugs were examined in a experimental model of pneumonia caused by chlamydia pneumoniae in leukopenic mice; their in vitro activities were also examined. the most potent agents in vitro were sparfloxacin (mics for c. pneumoniae kajaani and iol 207, (0.031 and 0.031 micrograms/ml, respectively), clarithromycin (0.031 and 0.031 micrograms/ml, respectively), and minocycline (0.031 and 0.031 micrograms/ml, respectively); these were ... | 1994 | 7986006 |
| lower respiratory tract infection with chlamydia pneumoniae. | chlamydia pneumoniae, also known as twar, is a common respiratory pathogen that can cause pneumonia, bronchitis, sinusitis, and pharyngitis. the clinical similarities between c pneumoniae infection and infection with other respiratory pathogens together with the lack, until recently, of readily available diagnostic tests for c pneumoniae have hindered its recognition and treatment in the outpatient setting. in this report, three patients with acute c pneumoniae infection from the acute respirato ... | 1994 | 7987518 |
| [species-specific monoclonal antibodies against chlamydia pneumoniae]. | the purified elementary bodies (ebs) of c. pneumoniae atcc vr1310 were used for primary immunization of male balb/c mice (8 weeks of age), with the boost following on day 14. spleen cells were fused with murine myeloma ns-1 cells on day 24 and hybrid cells were cloned by limiting dilution. two clones, p17c2 & p33c, secreting species-specific monoclonal antibodies (mabs) and immunoglobulin igg2a class were obtained after elimination of those clones that produced antibodies against c. trachomatis ... | 1994 | 7987714 |
| more on chlamydia pneumonia and meningoencephalitis. | | 1995 | 7990880 |
| [is coronary disease caused by an infection with chlamydia pneumoniae?]. | | 1994 | 7992422 |
| [the immunogenicity of a vaccine against enzootic abortion in sheep]. | immunogenicity of vaccine against enzootic abortion of ewes (epo) was evaluated in sheep and laboratory white mice. the vaccine contained purified and formalin-inactivated corpuscules of chlamydia psittaci. experiment was performed on ten sheep, slovak merino breed, which were negative before vaccination in serological assays and blastic transformation of lymphocytes (btl) tests. the animals were immunized subcutaneously with 2 ml of vaccine which contained 100 micrograms (sheep no. 1-4) and 20 ... | 1994 | 7992468 |
| [a case of pediatric chlamydia pneumoniae infection and properties of the isolate]. | chlamydia pneumoniae was isolated from the throat of a 2-year-old girl with upper respiratory illness. the isolate, shizuoka-37, was stained with c. pneumoniae specific monoclonal antibody (rr402), as well as the genus specific antibody (cultureset), but not with c. trachomatis specific monoclonal antibody (micro-trak). c. pneumoniae genome was amplified by polymerase chain reaction in the isolate. elementary bodies (eb) of the isolate was round shaped by electron micrograph. | 1994 | 7996018 |
| [activity of neutrophilic granulocytes and hematologic picture in rabbits immunized with chlamydia psittaci]. | the study was aimed at investigation of selected elements of nonspecific immunity (spontaneous and stimulated nbt reduction test and myeloperoxidase activity of neutrophilic granulocytes) and specific serological response in rabbits immunized twice with suspension of cells of c. psittaci inactivated by formaldehyde. specific antibodies were detected by complement fixation test and in a titer of 16 or higher were found between 42 and 56 day of the experiment. statistically significant decrease of ... | 1994 | 7996939 |
| [chlamydia pneumoniae: possibly, the third cause of epidemic bacterial pneumopathies?]. | | 1993 | 8008549 |
| chlamydia psittaci infections in birds: a review on the pathogenesis and histopathological features. | in this review the literature on the pathogenesis and histopathological features of chlamydia psittaci infections in birds and their significance for psittacosis/ornithosis in humans is summarized. models of experimental infections to elucidate the pathogenicity of avian strains are discussed briefly. | 1994 | 8009817 |
| the association of chlamydia pneumoniae infection and reactive airway disease in children. | to determine the possible association of chlamydia pneumoniae infection and reactive airway disease in children. | 1994 | 8019629 |
| enhancement of in vitro transcription by addition of cloned, overexpressed major sigma factor of chlamydia psittaci 6bc. | | 1994 | 8021204 |
| the role of branhamella ovis, mycoplasma conjunctivae and chlamydia psittaci in conjunctivitis of sheep. | smooth (s) and rough (r) types of branhamella ovis were used alone and in conjunction with mycoplasma conjunctivae and chlamydia psittaci in attempts to produce conjunctivitis in lambs. this was only successful with one s-type previously isolated from a clinical case of conjunctivitis. in experimental mixed infection, b. ovis contributed to the severity of ovine keratoconjunctivitis attributable to infection with mycoplasma conjunctivae. when b. ovis and c. psittaci were inoculated into the conj ... | 1994 | 8025837 |
| diagnostic utility of pcr-enzyme immunoassay, culture, and serology for detection of chlamydia pneumoniae in symptomatic and asymptomatic patients. | to assess the utility of pcr-enzyme immunoassay (eia) for diagnosis of acute infection with chlamydia pneumoniae, we compared tissue culture, pcr-eia, direct fluorescent-antibody (dfa) stain, and serology in studies with 56 patients with respiratory symptoms and 80 asymptomatic persons. thirty-five patients were positive by either culture or pcr-eia, and 101 were negative by both assays. thirty specimens from symptomatic patients and one from an asymptomatic patient were culture positive; 23 of ... | 1994 | 8027341 |
| chlamydia pneumonia and meningoencephalitis. | | 1994 | 8028636 |
| ultrastructural lung pathology of experimental chlamydia pneumoniae pneumonitis in mice. | the ultrastructural lung pathology of swiss webster mice on days 2, 4, 7, 11, 15, and 21 after intranasal inoculation of chlamydia pneumoniae ar-39 is described. the inflammatory infiltrate was predominantly polymorphonuclear leukocytes on day 2. by day 7, mononuclear cells were most prominent in the infiltrate. on day 2, chlamydial inclusions were found frequently in the bronchial ciliated epithelial cells and less frequently in the interstitial cells that appeared to be macrophages. free parti ... | 1994 | 8035039 |
| chlamydia pneumoniae (twar): a common agent in acute bronchitis. | patients seeking medical attention for respiratory infections were investigated with serology and culture for chlamydia pneumoniae to investigate the prevalence of c. pneumoniae in a specific geographical area and its association with respiratory disease. evidence for c. pneumoniae infection was found in approximately 25% of cases. 71% of patients with c. pneumoniae had symptoms from the lower respiratory tract as compared to 29% of the others. we conclude that c. pneumoniae can be a major cause ... | 1994 | 8036474 |
| the importance of interferon-gamma in an early infection of chlamydia psittaci in mice. | athymic mice (nu/nu) and their hairy littermates (nu/+) were infected experimentally with chlamydia psittaci and the role of endogenous interferon-gamma (ifn-gamma) on the resolution of the infection was studied. the pathological changes produced in the spleen, liver and lung were exacerbated by administration of a monoclonal antibody (mab) to ifn-gamma and an increased number of viable chlamydiae were recovered from the tissues of both nu/+ and nu/nu mice treated in this way. | 1994 | 8039814 |
| performance of three commercially available monoclonal reagents for confirmation of chlamydia pneumoniae in cell culture. | we evaluated the performance of three commercially available monoclonal antibodies for confirmation of the presence of chlamydia pneumoniae in cell culture by examining their abilities to stain inclusions of eight strains of c. pneumoniae. the antibodies tested were two unconjugated c. pneumoniae-specific monoclonal reagents and one conjugated genus-specific reagent. all three produced similar intensities of staining of c. pneumoniae, with some strain-to-strain variation. methanol appeared to be ... | 1994 | 8051280 |
| evaluation of the sensitivity and specificity of polymerase chain reaction test kit, amplicor chlamydia trachomatis. | the sensitivity and specificity of the polymerase chain reaction (pcr) test kit, amplicor chlamydia trachomatis, were examined by the use of purified elementary bodies (ebs), cells having inclusions containing reticulate bodies alone and 20 clinical isolates. the numbers of eb and inclusion of c. trachomatis at the detection limit were determined to be approximately 2 to 4 ebs and one inclusion per assay, respectively. no reaction occurred for c. psittaci and c. pneumoniae. all clinical isolates ... | 1994 | 8052164 |
| animal models for ocular infections. | | 1994 | 8057937 |
| animal models for urogenital infections. | | 1994 | 8057939 |
| radiographic appearance of chlamydia pneumoniae (twar strain) respiratory infections. cbpis study group. community-based pneumonia incidence study. | to report the spectrum of radiographic findings associated with a new respiratory pathogen: chlamydia pneumoniae (twar strain). | 1994 | 8058954 |
| [serodiagnosis of chlamydia trachomatis and chlamydia pneumoniae. evaluation comparing 2 methods: microimmunofluorescence and elisa. a study of 216 congolese sera]. | our purpose was to compare two assays for c. trachomatis and c. pneumoniae serology: immunofluorescence and elisa. with both assays, we tested 216 sera from two populations: risk population of std (sexually transmitted disease) (women) and a control population "blood donors". positives percentages of each population were compared by two assays: 87% in mif and 76% in elisa (women population); 64.8% in mif and 53.7% in elisa (blood donors population). results were not significantly different. in c ... | 1994 | 8061532 |
| [the prevalence of anti-chlamydia trachomatis and anti-chlamydia pneumoniae antibodies in brazzaville]. | the prevalence study of antibodies to chlamydia trachomatis and chlamydia pneumoniae in brazzaville were screened from 108 women (56 pregnant women, 18 infertile women and 34 women affected with genital tract infections) and 108 blood donors (control subjects) by indirect microimmunofluorescent assay. 57.4% of studied women were carrying chlamydia trachomatis antibodies, and 51.8% had c. pneumoniae antibodies. prevalence of chlamydia antibodies by women group studied was estimated to be: in preg ... | 1994 | 8061533 |
| abortion and subsequent excretion of chlamydiae from the reproductive tract of sheep during estrus. | chlamydia psittaci serovar 1 infection in pregnant sheep typically causes abortion or the birth of weak lambs. eight sheep that experienced chlamydia-induced abortion during their first pregnancy were successfully rebred yearly for the past 2 years. chlamydia-specific lipopolysaccharide was detectable for approximately 3 weeks in vaginal swabs taken from the experimentally infected sheep following abortion. there was no evidence of chlamydiae in vaginal, placental, or neonatal samples obtained i ... | 1994 | 8063395 |
| the development of proliferative responses of ovine peripheral blood mononuclear cells to chlamydia psittaci during pregnancy. | in vitro lymphoproliferative responses to chlamydia psittaci elementary bodies were detected in the peripheral blood mononuclear cells of pregnant sheep infected with c. psittaci. these responses were suppressed in cells collected in the immediate peri-parturient period, but returned to levels significantly above background within 14 days. infection also suppressed the lymphoproliferative response to the t-cell mitogen con a until abortion or lambing, but did not affect the proliferative respons ... | 1994 | 8066993 |
| evaluation of five immunoassays for detection of chlamydia psittaci in cloacal and conjunctival specimens from turkeys. | five commercially available immunoassays were evaluated for the detection of chlamydia psittaci in cloacal and conjunctival swabs from industrially raised turkeys: imagen (dako diagnostics, ely, cambridgeshire, united kingdom), chlamydia cel-vet if (cellabs, brookvale, australia), ideia (dako diagnostics), celisa (cellabs), and clearview (unipath, bedford, united kingdom). results were compared with isolation in buffalo green monkey cells as a reference method. for the conjunctival samples, the ... | 1994 | 8077391 |
| [lung infections in children. iv. pneumonia due to chlamydia pneumoniae]. | chlamydia pneumoniae is the third strain of chlamydia and transmission is presumed to be by droplet spread from symptomatic patients. the authors show a literature scientific review on subject-matter emphasizing several sporadic and epidemic case of illness in every age, first months excepted. the described cases are few and therefore clinical characteristics are shadowy. certain clinical features are suggesting of severe pneumonia with fever and pharyngitis without exudate. in the childhood and ... | 1994 | 8090147 |
| prevalence of chlamydia pneumoniae in acute lower respiratory infection in the pediatric population in japan. | chlamydia pneumoniae has been established as an important etiologic agent of acute respiratory tract infection in humans, especially in adults. however, there is little information available on c. pneumoniae infection in the pediatric age group. the microimmunofluorescence test and chlamydia pneumoniae-specific polymerase chain reaction (pcr) method were applied to reveal the role of c. pneumoniae as an etiologic agent of acute lower respiratory tract infection in children in japan. among 136 pa ... | 1994 | 8091972 |
| infection as a cause of asthma. | | 1994 | 8092566 |
| in vitro activities of opc-17116, a new quinolone; ofloxacin; and sparfloxacin against chlamydia pneumoniae. | the in vitro susceptibilities of 12 strains of chlamydia pneumonia to a new quinolone, opc-17116; ofloxacin; and sparfloxacin were determined. opc-17116 was slightly less active than sparfloxacin but more active than ofloxacin, with a mic for 90% of strains tested and a minimal chlamydiacidal concentration for 90% of strains tested of 0.5 micrograms/ml. | 1994 | 8092845 |
| increasing prevalence of specific antibodies to chlamydia pneumoniae in sweden. | | 1993 | 8094155 |
| chlamydia pneumoniae and atherosclerosis. | | 1993 | 8096020 |
| restriction fragment length polymorphisms of rrna as genetic markers to differentiate chlamydia spp. | restriction fragment length polymorphisms (rflps) of rrna genes of chlamydia spp. were analyzed. a southern analysis of chromosomal dna digests with cloned rrna gene probes revealed the presence of one locus for rrna genes on chromosomal dnas in chlamydia psittaci, chlamydia pecorum, and chlamydia pneumoniae and two loci in chlamydia trachomatis. the rflps of rrna genes were characteristic for each chlamydia sp. dna probes cloned from flanking regions of the rrna genes of avian c. psittaci hybri ... | 1993 | 8102247 |
| chlamydia psittaci. an uncommon cause of community-acquired pneumonia. | chlamydia psittaci is an uncommon cause of community-acquired pneumonia. fewer than 200 cases of psittacosis are reported annually to the centers for disease control and prevention; however, many cases are believed to be unreported. unrecognized cases not properly treated may result in significant morbidity and possibly have a fatal outcome. we describe a 42-year-old man with multilobar pneumonia and respiratory compromise secondary to infection with c psittaci. the patient also exhibited hepati ... | 1993 | 8111531 |
| diagnostic value of rapid detection of chlamydia trachomatis by using amplified enzyme immunoassay in infants with respiratory infections. | the diagnostic value of amplified enzyme immunoassay (ideia chlamydia test) was compared with that of standard tissue culture in specimens obtained from pediatric patients. of 286 clinical specimens, chlamydial antigen was detected in 34 by ideia chlamydia. chlamydia trachomatis was isolated from 30 specimens and c. pneumoniae from one specimen. ideia had excellent sensitivity and specificity relative to cell culture. | 1993 | 8112033 |
| lack of evidence of chlamydia pneumoniae infection in infants with acute lower respiratory tract disease. | in order to determine whether there is serologic evidence of chlamydia pneumoniae infection in young infants with acute lower respiratory tract infection, serum samples from 86 subjects aged less than 6 months were assayed for igg and igm antibodies to chlamydia pneumoniae using a microimmunofluorescence method. infants hospitalized in toronto, canada, were enrolled between 15 march 1991 and 15 march 1992. no patient had infection determined by the serologic results. igg antibody was detected at ... | 1993 | 8112356 |
| remarkable sequence relatedness in the dna encoding the major outer membrane protein of chlamydia psittaci (koala type i) and chlamydia pneumoniae. | dna encoding the major outer membrane protein (momp) of the koala type-i strain of chlamydia psittaci (pathogen responsible for blindness and infertility in koalas) was cloned and sequenced. comparison with momp gene sequences from other chlamydial species revealed a remarkable degree of homology (> 97%) with that of the human pathogen, chlamydia pneumoniae. in comparison, the sequence only shared 75% dna sequence homology with other c. psittaci members and 69% homology with c. trachomatis. the ... | 1994 | 8125292 |
| the in-vitro activity of a new highly active quinolone, du-6859a. | | 1993 | 8125840 |
| [hypoxemic pneumopathy caused by chlamydia pneumoniae]. | | 1993 | 8127805 |
| primary pathogenicity of an european isolate of chlamydia psittaci from turkey poults. | chlamydia psittaci was isolated as the sole pathogenic agent from a severe outbreak of respiratory disease in a commercial broiler turkey farm in the netherlands. the mortality rate in the flocks was 65%. clinical signs included conjunctivitis, swelling of the sinus infraorbitalis and sneezing. cloacal excretion of chlamydia was demonstrated in twelve out of fifteen birds examined by a direct immunofluorescence test. in all the fifteen birds antibodies against chlamydia psittaci were detected in ... | 1993 | 8128594 |
| chlamydia pneumoniae--a new causative agent of reactive arthritis and undifferentiated oligoarthritis. | to examine whether reactive arthritis (rea) known to occur after a urogenital infection with chlamydia trachomatis can also follow an infection with chlamydia pneumoniae, a recently described species of chlamydiae that is a common cause of respiratory tract infections. | 1994 | 8129453 |
| outbreak of chlamydia pneumoniae infection in former injection-drug users. | in a retrospective analysis of lower respiratory tract infections in an ex-injection-drug users community, we found an outbreak (april to july 1991) of chlamydia pneumoniae infection. the epidemic occurred in a group of 26 community members (23 men and 3 women, mean age, 28.9--3 years) living and working together, who underwent acute and convalescent serologic tests for mycoplasma pneumoniae, legionella pneumophila, cytomegalovirus, adenovirus, coxiella burnetii, and chlamydia pneumoniae. all su ... | 1994 | 8131545 |
| pathogenetic mechanisms and epidemiology of chlamydia pneumoniae. | the antibody prevalence data indicate that c. pneumoniae infections are common worldwide and more frequently occur in middle-aged and elderly males than in females. c. pneumoniae infections are first acquired in childhood in heavily populated areas, whereas in northern countries, first infections are generally at teenage and in scandinavia, typically at the time of military service. all chlamydial species tend to cause chronic infections, with severe sequelae developing 10 to 50 years after the ... | 1993 | 8131790 |
| chlamydia pneumoniae infection as a risk factor in acute myocardial infarction. | while early observations on the possible connection between chlamydia and arteriosclerosis remain unnoticed, it was found recently that in acute myocardial infarction (ami) a sero response to an epitope of chlamydial lipopolysaccharide (lps) could be demonstrated in about 70% of cases. moreover, steadily elevated titres against chlamydia pneumoniae in patient sera pointed to a possibility that chronic infection due to the agent was exacerbated in ami. this assumption has been further supported b ... | 1993 | 8131791 |
| chlamydia pneumoniae, strain twar and atherosclerosis. | infection with chlamydia pneumoniae, strain twar, has been associated with atherosclerotic cardiovascular disease in two types of investigations, seroepidemiological and morphological-molecular. a series of seroepidemiological studies from finland and the united states have shown a statistically significant association between several types of twar antibody, including immune complexes, and atherosclerotic disease of the coronary and carotid arteries. the morphological-molecular studies have show ... | 1993 | 8131792 |
| cytokine-mediated indoleamine 2,3-dioxygenase induction in response to chlamydia infection in human macrophage cultures. | the purpose of this study was to characterize further the events leading to the metabolic degradation of tryptophan in chlamydia-infected cultures in the absence of added interferon (ifn). macrophages on coverslips were infected with chlamydia psittaci, and tryptophan decyclization was determined 24 h later by reverse-phase high-performance liquid chromatography. tryptophan metabolites cochromatographed with kynurenine and n-formylkynurenine, the end products of tryptophan decyclization by the i ... | 1994 | 8132317 |
| chlamydial serology in genital infections: immunocomb versus ipazyme. | the immunocomb chlamydia trachomatis igg/iga (orgenics, israel) is a new serologic test using c. trachomatis l2 elementary bodies (washington research foundation, seattle) as antigen. the ipazyme igg/iga test (savyon, israel) employs whole cells with c. trachomatis l2 inclusions, i.e. elementary and reticulate bodies. theoretically, the immunocomb is expected to be less cross-reactive (lps) with chlamydia pneumoniae than the ipazyme (lps and reticulate body group specific antigens). compared wit ... | 1993 | 8132368 |
| [experimental study on the mechanisms of chlamydia pneumoniae respiratory infection in mice with former chlamydial exposure]. | to compare the differences in the severities, host defense responses and clinical courses c. pneumoniae respiratory tract infections between the initial and second challenge of chlamydia, an experimental c. pneumoniae respiratory infection model using mice was established and the following studies were carried out. for the initial infection mice were challenged with c. pneumoniae, strain tw-183, by nasal instillation. no animals died from this initial infection. the second exposure to c. pneumon ... | 1994 | 8138679 |
| chlamydial serologic studies and recurrent spontaneous abortion. | our purpose was to investigate the putative association between immunoglobulin g antibodies to chlamydia trachomatis and recurrent spontaneous abortions. | 1994 | 8141201 |
| [community-acquired pneumonia: prospective study of 101 adult, immunocompetent patients for 1 year]. | a one year prospective study was carried out to assess the etiology of community-acquired pneumonia (cap), and also to know the incidence, characteristics and evolution of infection by chlamydia pneumoniae; and the effectiveness of dna probes in cap due to mycoplasma pneumoniae and legionella. | 1993 | 8142501 |
| two family outbreaks of chlamydia pneumoniae infection. | during autumn 1992, we observed two unrelated family outbreaks of chlamydia pneumoniae infection. family a consisted of grandmother (aged 77 yrs), father (aged 41 yrs), mother (aged 38 yrs), daughter (aged 10 yrs), and two sons (aged 6 yrs and 3 months, respectively). the grandmother and daughter suffered from pneumonia, father from pharyngitis and bronchitis and the older son from mild bronchitis. no symptoms were recorded in the mother and younger son. symptomatic subjects showed a fourfold in ... | 1994 | 8143807 |
| homogeneity of the major outer membrane protein gene of feline chlamydia psittaci. | thirteen feline chlamydia psittaci strains isolated in various countries over a 50-year period were examined by restriction mapping of the major outer membrane protein (momp) gene obtained after dna amplification by the polymerase chain reaction and compared with avian, ovine and guinea pig inclusion conjunctivitis (gpic) c psittaci strains. all the feline isolates produced a unique alui pattern distinct from the other c psittaci strains and were characterised by a typical fragment doublet of 18 ... | 1994 | 8146443 |
| prevalence of chlamydia pneumoniae antibodies in patients with acute respiratory infections in israel. | to evaluate the prevalence of antibodies to chlamydia pneumoniae (twar) in relation to other aetiological agents of acute respiratory infections in israeli patients. | 1994 | 8163694 |
| the role of chlamydia pneumoniae in severe acute tonsillitis. | chlamydia pneumoniae has been implicated as a cause of tonsillitis and pharyngitis, but the incidence has varied from one to 19 per cent in various studies. we investigated 51 patients admitted to university college hospital, galway, with severe tonsillitis. throat swabs were examined for evidence of chlamydia pneumoniae using a direct monoclonal antibody test. blood was taken for serology from 45 patients. a further specimen was taken at six weeks. a control group of 32 blood bank sera was used ... | 1994 | 8163914 |
| chlamydia pneumoniae strain twar pharyngitis in us air force basic trainees. | chlamydia pneumoniae has recently been shown to be a cause of pharyngitis. because the impact of this pathogen on united states air force basic trainees is unknown, the authors undertook a prospective study to evaluate the prevalence of c pneumoniae. of 118 asymptomatic basic trainees, 43% had preexisting antibodies to c pneumoniae and 0.9% had serologic evidence of c pneumoniae infection. of 226 symptomatic basic trainees, only four (1.8%) met the criteria for serologic evidence of acute c pneu ... | 1994 | 8169158 |
| [a case of adult chlamydia pneumoniae pneumonia diagnosed from a culture method]. | we diagnosed a 41-year-old female patient to be suffering from chlamydia pneumoniae (c. pneumoniae) by using pcr and culture methods. she had a prolonged dry cough and slight fever. her chest roentgenogram showed a segmental infiltration in the middle of the right lung field. we treated her with 400 mg of cefpodoxime proxetil (cpdx-pr) per day. on the 4th day after beginning the treatment with cpdx-pr, she still complained of a productive cough. we changed the treatment by using 300 mg of roxith ... | 1994 | 8176283 |
| [the diagnosis of primary atypical pneumonias]. | the article studies the peculiarities of clinical course and symptoms of primary non-typical pneumonias that are widespread to-day, and especially among interconnected communities. the authors show diagnostical problems of etiological verification of these forms of acute pneumonia. taking into account the modern achievements of medical science and practice the article discloses the main diagnostical indices of mycoplasma [correction of microplasmatic], legionella and chlamydia infections. | 1994 | 8178497 |
| identification of chlamydia pneumoniae-specific protein antigens in immunoblots. | the immunoblot patterns of 248 sera, all examined previously by the microimmunofluorescence test (mif) for species-specific chlamydia antibodies, were analyzed. predominant specific antibody activity was directed to the 54 kda protein of chlamydia pneumoniae, which was recognized by 93% of sera positive for chlamydia pneumoniae by mif but by only 2% of sera positive for chlamydia trachomatis and negative for chlamydia pneumoniae and by 3% of sera negative for both chlamydia pneumoniae and chlamy ... | 1993 | 8187792 |
| antiparasitic and antiproliferative effects of indoleamine 2,3-dioxygenase enzyme expression in human fibroblasts. | studies were carried out to evaluate the proposed role of indoleamine 2,3-dioxygenase (indo) induction in the antimicrobial and antiproliferative effects of gamma interferon (ifn-gamma) in human fibroblasts. the indo cdna coding region was cloned in the pmep4 expression vector, containing the metallothionein (mtii) promoter in the sense (+ve) or the antisense (-ve) orientation. human fibroblasts (gm637) stably transfected with the sense construct expressed indo activity after treatment with cdcl ... | 1994 | 8188349 |
| enhancement of in vitro transcription by addition of cloned, overexpressed major sigma factor of chlamydia psittaci 6bc. | obligate parasitic bacteria of the genus chlamydia possess a developmental cycle that takes place entirely within eucaryotic host cells. because standard methods of genetic analysis are not available for chlamydiae, an in vitro transcription system has been developed to elucidate the mechanisms by which chlamydiae regulate gene expression. the in vitro system is specific for chlamydial promoters but is inefficient, presumably because the rna polymerase is not saturated with sigma factor. therefo ... | 1994 | 8188604 |
| [twar and heart disease. a questionable connection]. | | 1994 | 8189970 |
| chlamydial etiology of acute lower respiratory tract infections in children in the sudan. | the role of chlamydia pneumoniae in 110 sudanese children with signs of acute lower respiratory tract infections (alri) was investigated. four (3.6%) had evidence of c. pneumoniae infection, of whom 3 were culture-positive, while 1 had an antibody response suggesting a recent infection. igg antibodies at a titer of > or = 1:32 to c. pneumoniae, chlamydia psittaci and chlamydia trachomatis were detected in 27 (24.5%), 27 (24.5%) and 7 (6.4%) of the 110 alri cases, respectively. c. pneumoniae, c. ... | 1994 | 8193496 |
| chlamydia pneumoniae igg antibody prevalence in south-western and eastern finland in 1982 and 1987. | chlamydia pneumonia igg antibody prevalence was examined in a representative sample (2342 subjects) of the population aged 25-59 years in south-western and eastern finland in 1982 and 1987. microimmunofluorescence was used to measure igg antibodies. prevalence of c. pneumoniae was modelled using the glim statistical package assuming that the prevalence had a binomial distribution. the prevalence was assumed to be a function of the year, subjects' gender, age and place of residence. the effect of ... | 1994 | 8194914 |
| characterization of chlamydia pneumoniae species-specific proteins immunodominant in humans. | proteins of chlamydia pneumoniae immunodominant in humans were characterized with the sera of 13 patients who were not likely to have been exposed to c. trachomatis or c. psittaci. the serological responses among these patients were similar on a qualitative basis, but some differences were found quantitatively. however, the serological responses of the patients who were infected with c. pneumoniae differed markedly from those of two patients who were infected with c. trachomatis and two who were ... | 1994 | 8195362 |
| interference of immunoglobulin g (igg) antibodies in iga antibody determinations of chlamydia pneumoniae by microimmunofluorescence test. | in the microimmunofluorescence test for measuring immunoglobulin a (iga) antibodies against chlamydia pneumoniae, removal of interfering igg antibodies made iga antibody reactivity patterns in 952 serum samples easier to interpret, prozone effects disappeared, and titers increased, especially in the sera with high igg titers. iga rheumatoid factors did not interfere in the assay. | 1994 | 8195403 |
| asthma and chlamydial infection: a case series. | adult-onset asthma is frequently associated with antecedent respiratory symptoms that could represent either previously undiagnosed asthma or previous lung infections that result in subsequent asthma. to further investigate a reported association of chlamydia pneumoniae infection and adult reactive airway disease, we looked for evidence of atypical infections in patients with acute wheezing and nonwheezing respiratory illnesses. | 1994 | 8195733 |
| current topics of chlamydial respiratory tract infections--special reference to the epidemiology and clinical findings of chlamydia pneumoniae infections in japan. | | 1993 | 8204976 |
| chlamydia pneumoniae. | | 1994 | 8205921 |
| [pilot study of the occurrence of chlamydia psittaci infections in commercial turkey flocks in niedersachsen]. | turkeys from 8 commercial flocks, of which were 6 clinically healthy, were examined by use of enzyme-linked immunosorbent assay systems for genus-specific chlamydia antigens and also for antibodies against chlamydia psittaci in 4 flocks. results of the tests indicate the presence of chlamydia psittaci infections in all 8 flocks. the percentage of combined cloacal and conjunctival swabs positive for chlamydia antigen ranged from 20-91% [20-70%] whereas the percentage of antibody-positive serum sa ... | 1994 | 8205970 |
| chlamydia pneumoniae. | | 1993 | 8211882 |
| investigation of a unique time-space cluster of sarcoidosis in firefighters. | a unique cluster of three cases of sarcoidosis developed recently among 10 white firefighters who trained together as apprentices in 1979. this led us to hypothesize that firefighters are at increased risk of this condition because of the combined effect of smoke exposure and infection with a communicable agent, such as chlamydia pneumoniae, a recently proposed cause of sarcoidosis. we conducted a case-finding questionnaire survey of 1,282 active and retired male providence firefighters and poli ... | 1993 | 8214953 |
| rapid diagnosis of chlamydia psittaci pneumonia. | two cases of chlamydia psittaci pneumonia are presented. in each, a rapid diagnosis was made through the use of direct immunofluorescent antibody staining of respiratory secretions with monoclonal antibodies to chlamydial antigens. in one case the diagnosis was confirmed by the isolation of the causative organism from sputum and a pharyngeal swab. chlamydial lipopolysaccharide was detectable in sputum from this patient in an enzyme immunoassay. serological responses to c. psittaci, chlamydia tra ... | 1993 | 8218673 |
| an epidemic of infections due to chlamydia pneumoniae in military conscripts. | a prospective observational study of an epidemic of infection due to chlamydia pneumoniae strain twar in finnish military trainees provided new information on immunity following infection, the range of clinical syndromes and complications, and cell culture isolation. one-half of the trainees studied (43 of 86) had laboratory evidence of c. pneumoniae infection. the etiologic association of c. pneumoniae with disease was strengthened by the sharp increase in cases of pneumonia and in outpatient v ... | 1993 | 8218684 |
| clinical and laboratory findings in chronic conjunctivitis in cats: 91 cases (1983-1991). | clinical findings and laboratory test results from 91 cats with chronic conjunctivitis were studied to determine the causes of the disease and the sensitivity of diagnostic procedures used, and to identify correlations between results of various diagnostic procedures and clinical or signalment variations. mean age of affected cats was 2.9 +/- 2.7 years (+/- sd), with a range from 1 month to 11 years. conjunctivitis was more likely to be bilateral (56 cats) than unilateral (35 cats). in cats test ... | 1993 | 8226238 |
| evidence that chlamydia pneumoniae causes pneumonia and bronchitis. | an epidemic often provides an opportunity to obtain evidence of the etiologic association of a microorganism with disease. chlamydia pneumoniae twar is a newly recognized organism whose relationship to disease is not completely understood. an outbreak of c. pneumoniae infections from november 1990 to february 1991 was studied in university of washington students. twelve twar infections were identified serologically in 54 students with acute respiratory disease. the organism was isolated from 7 o ... | 1993 | 8228356 |
| [chlamydia pneumoniae: clinical, epidemiological and laboratory aspects]. | | 1993 | 8234732 |
| bovine chlamydiosis in the united kingdom. | | 1993 | 8236686 |
| immuno-dot blot as a rapid diagnostic method for detection of chlamydial infection in koalas (phasolarctos cinereus). | the sensitivity and specificity of an immunoscreening test for anti-chlamydial antibodies in koala (phasolarctos cinereus) serum were determined after the adsorption of non-specific antibodies. the results of the test were compared with complement fixation tests, tissue culture, gene probe analysis and dot blot immunoscreening for host-borne chlamydial antigen. the immunoscreening test was the most sensitive test for the identification of chlamydial infection in koala serum samples, furthermore ... | 1993 | 8236690 |
| an estimate of the prevalence of enzootic abortion of ewes in scotland. | the prevalence of enzootic abortion of ewes in scotland was estimated over a period of five years. between 1987 and 1991, 30.7 per cent of all flocks with breeding ewes in scotland submitted ovine abortion material, and of these flocks 28 per cent showed evidence of the infection, giving a prevalence of 8.6 per cent. regional differences were observed in both the submission rate and the prevalence. | 1993 | 8236713 |
| comparison of different serological methods for the determination of antibodies to chlamydia psittaci in pigeon sera. | several methods for detecting antibodies to chlamydia psittaci using sera from pigeons were compared with regard to their sensitivity, specificity and efficacy. the reference method used was indirect immunofluorescence (ifi), which uses as antigen intracellular inclusions in mccoy cell monolayers. indirect micro-immunofluorescence (mif) using as antigen c. psittaci cultured on yolk sacs of embryonated eggs, direct and indirect complement fixation tests (cft and icft, respectively), and enzyme-li ... | 1993 | 8237193 |
| past infection by chlamydia pneumoniae strain twar and asymptomatic carotid atherosclerosis. atherosclerosis risk in communities (aric) study investigators. | to determine whether past infection by chlamydia pneumoniae strain twar is associated with asymptomatic atherosclerosis. previous studies have linked this organism with symptomatic coronary heart disease. | 1993 | 8238066 |
| in vitro activity of azithromycin (cp-62,993) against chlamydia trachomatis and chlamydia pneumoniae. | the in vitro susceptibilities of 49 strains of chlamydia trachomatis and 3 strains of chlamydia pneumoniae to azithromycin and tetracycline or doxycycline were determined. the mic of azithromycin ranged from < or = 0.06 to 1.0 micrograms/ml, the mic of tetracycline ranged from 0.03 to 0.12 micrograms/ml, and the mic of doxycycline ranged from 0.015 to 0.06 micrograms/ml against c. trachomatis. the mic ranges for c. pneumoniae were 0.12 to 0.25 micrograms/ml for azithromycin and 0.06 to 0.12 micr ... | 1993 | 8239579 |
| serum reactivity to chlamydia trachomatis and c. pneumoniae antigens in patients with documented infection and in healthy children by microimmunofluorescence and immunoblotting techniques. | chlamydia trachomatis and c. pneumoniae are both important human pathogens. antigenic cross-reactivity between the two species may complicate serologic diagnosis of infection with one or the other agent. in this study we examined sera of persons with chlamydia infections and of healthy children by microimmunofluorescence (mif) against c. trachomatis l2 antigen and against c. pneumoniae tw-183 antigen to explore the degree of cross-reactivity found by these two methods. likewise, the cross-reacti ... | 1993 | 8240791 |
| incidence of community-acquired pneumonia caused by chlamydia pneumoniae in italian patients. | the incidence of chlamydia pneumoniae as a cause of community-acquired pneumonia was evaluated in a one-year prospective study in 108 patients with community-acquired pneumonia. the bacteriological diagnosis was based on culture of sputum or bronchial aspirate and examination of acute and convalescent phase sera for mycoplasma pneumoniae, legionella pneumophila and chlamydia pneumoniae. a definitive microbiological diagnosis was obtained in 58 (54%) patients. chlamydia pneumoniae was the causati ... | 1993 | 8243486 |
| [changing pattern of chlamydia respiratory tract infections--with special reference to infections in japan]. | | 1993 | 8245644 |
| chlamydia pneumoniae in swedish patients. | chlamydia pneumoniae infections have earlier been described as mycoplasma-like illnesses in young people, and also appear to be associated with community-acquired pneumonia in adults. in this retrospective study, 12.2% (23/188) of patients with pneumonia who required hospitalization during the 3 years 1985-87 had serological evidence of recent c. pneumoniae infection. many of these patients had symptoms similar to ornithosis. the most interesting finding was that half of the patients with a 4-fo ... | 1993 | 8248741 |
| chlamydia pneumoniae as a cause of reactive arthritis. | | 1993 | 8252327 |
| spontaneous cure of acute bronchitis caused by chlamydia pneumoniae in a 15-year-old boy. | chlamydia pneumoniae was isolated from the pharyngeal swab of a 15-year-old patient with acute bronchitis. the serum igm antibody against c.pneumoniae was elevated up to 160-fold in the acute phase and decreased to 20-fold in the convalescent phase using the microimmunofluorescence (mif) test. igg antibody titers in the acute phase and the convalescent phase were 40-fold and 160-fold respectively using the mif test. the patient recovered from the bronchitis without any effective treatment, indic ... | 1993 | 8253607 |
| protein antigens of chlamydia psittaci present in infected cells but not detected in the infectious elementary body. | ocular infection of guinea pigs with the guinea pig inclusion conjunctivitis (gpic) strain of chlamydia psittaci produces a clinical condition representative of acute chlamydial conjunctivitis in humans. guinea pigs which had recovered from two challenges with gpic were used as a source of sera for the identification of antigens present in gpic-infected tissue culture cells but absent in the infectious elementary body (eb). immunoblots of lysates of infected hela cells probed with the convalesce ... | 1994 | 8262615 |
| growth in serum-free medium improves isolation of chlamydia pneumoniae. | infectivity titers were determined for eight chlamydia pneumoniae strains simultaneously grown in serum-free and serum-supplemented cell culture media. use of serum-free medium resulted in a 10- to 50-fold increase in the susceptibility of hl cells to chlamydial infection. comparative primary isolation of a wild-type strain also produced higher inclusion counts in a serum-free environment. serum-free cultivation is recommended to increase the efficiency of c. pneumoniae isolation from clinical m ... | 1993 | 8263198 |
| atypical pneumonia due to chlamydia pneumoniae: a case report. | a first case of chlamydia pneumoniae pneumonia in malaysia is reported. the diagnosis was made by a significant change in c. pneumoniae antibody titre. the infection responded well to a course of erythromycin. | 1993 | 8266214 |
| preliminary data on chlamydia pneumoniae seroprevalence in hiv-1 infected children. | | 1993 | 8267281 |
| detection of chlamydia pneumoniae by polymerase chain reaction-enzyme immunoassay in an immunocompromised population. | chlamydia pneumoniae has now been associated with pneumonia, bronchitis, pharyngitis, acute chest syndrome of sickle cell disease, and asthma. because of the difficulty of primary isolation and tissue-culture adaptation of this organism, we used a previously developed polymerase chain reaction-enzyme immunoassay (pcr-eia) to screen 132 culture-negative bronchoalveolar lavage (bal) specimens from 108 immunocompromised patients (34% of whom were positive for human immunodeficiency virus) and 7 hea ... | 1993 | 8268355 |
| chlamydia psittaci as a cause of lethal bacterial endocarditis. | | 1993 | 8268378 |
| [a case of severe interstitial pneumonia probably due to chlamydia pneumoniae]. | a 64-year-old male was admitted to our hospital with dyspnea and high fever. the patient had a relative bradycardia and severe hypoxemia. velcr rales were heard throughout the entire lung fields. leucocytosis was absent. chest x-ray showed bilateral diffuse reticular shadows. corticosteroid pulse therapy and minocycline were introduced on the suspicion of either idiopathic interstitial pneumonia or chlamydial pneumonia. subsequently, his symptoms gradually improved. although the patient had no h ... | 1993 | 8271671 |
| genital chlamydia trachomatis infection in australia. | | 1994 | 8271993 |