| characterization of the apolipoprotein ai and ciii genes in the domestic pig. | the apolipoproteins (apo) ai and ciii are important constituents of triglyceride-rich lipoproteins and high-density lipoproteins. in humans, apo ai is believed to play an important protective role in the pathogenesis of arteriosclerosis, whereas apo ciii might be involved in the development of hypertriglyceridemia. both human genes are located within a gene cluster on chromosome 11. although the domestic pig has been widely used as an animal model in arteriosclerosis and lipid research, the porc ... | 1993 | 8468059 |
| modulation of transforming growth factor-beta 1 stimulated elastin and collagen production and proliferation in porcine vascular smooth muscle cells and skin fibroblasts by basic fibroblast growth factor, transforming growth factor-alpha, and insulin-like growth factor-i. | during tissue repair and development, matrix accumulation is modulated as multiple signals impinge on target cells. we have investigated the effects of combinations of the mitogenic cytokines, basic fibroblast growth factor (bfgf), transforming growth factor alpha (tgf-alpha), and insulin-like growth factor-1 (igf-1) with transforming growth factor-beta 1 (tgf-beta 1) with respect to the production of two matrix components, elastin and type i collagen. using specific enzyme-linked immunoassays f ... | 1993 | 8468360 |
| zygotene-pachytene substaging and synaptonemal complex karyotyping of boar spermatocytes. | synaptonemal complex analysis, by electron microscopy of spread spermatocytes after phosphotungstic acid staining, made possible description of the chromosomal synaptic patterns and the synaptonemal complex karyotype of the pig (sus scrofa domestica). the autosomal synaptic pattern in conjunction with the sex chromosome morphology and pairing behaviour can serve as a reference for the meiotic cell progression from the zygotene stage to the pachytene. the autosomes started terminal synapsis at ea ... | 1993 | 8478210 |
| intramyocardial hypercarbic acidosis during cardiac arrest and resuscitation. | to define changes in intramyocardial ph and pco2 during cardiac arrest and resuscitation. | 1993 | 8504660 |
| [the distribution and biology of capillaria garfiai from sus scrofa]. | the infestation extent of wild boars (sus scrofa) with capillaria garfiai gallégo & mas-coma, 1975 in east-austria and the localisation of the nematodes in the tongue (n = 159) were examined. the infestation extent (prevalence) was between 66.6 and 90.9 percent. concerning the location of the parasites in the tongue there was a striking difference between c. garfiai males and females. so, the number of c. garfiai females continuously decreased from the first to the fourth quarter of the tongue, ... | 1993 | 8508219 |
| detection of tetracycline resistance determinants in pig isolates from three herds with different histories of antimicrobial agent exposure. | a total of 114 gram-negative fecal isolates from domestic pigs in herds with different histories of antimicrobial agent exposure were screened for the presence of plasmid dna and specific tetracycline resistance determinants. more than 84% of the isolates harbored plasmid dna, which ranged in size from 2.1 to 186 kb. a total of 78 isolates (68.4%) were resistant to tetracycline at concentrations greater than 4 micrograms/ml. plasmid dnas from about 56% of the tetracycline-resistant isolates hybr ... | 1993 | 8517740 |
| mr imaging of gadolinium-dtpa-bma-enhanced reperfused and nonreperfused porcine myocardial infarction. | to investigate whether gd-dtpa-bma-enhanced mr imaging permits differentiation between reperfused and nonreperfused myocardial infarction, myocardial infarction was induced in 12 domestic pigs. in 6 pigs, gd-dtpa-bma, 0.3 mmol/kg b.w. was administered i.v. 60 min after the occlusion. in 6 other pigs, the infarctions were reperfused 80 min after the occlusion, followed by injection of gd-dtpa-bma after 20 min of reperfusion. radiolabeled microspheres were used to confirm zero-flow during the occl ... | 1995 | 8519575 |
| pathogenicity of artyfechinostomum oraoni in naturally infected pigs. | in an attempt to establish the diarrhoeogenic potential of the newly identified artyfechinostomum oraoni, which was associated with human diarrhoea in a tribal community near calcutta, india, two naturally infected domestic pigs of the locality were followed in captivity. both pigs developed fatal diarrhoea after 5 months. the autopsy revealed a massive infection with the echinostome on a haemorrhagic and oedematous mucosa of the jejunum and duodenum extending up to pyloric end of the stomach. i ... | 1995 | 8525286 |
| genetic differences in recombination frequency in the pig (sus scrofa). | a comparison has been performed on 3 recently published linkage maps of the pig, hereafter designated as the american (a), european (e), and swedish (s) maps. the cumulated distances between common markers in these 3 maps were in the ratio 1.00 (a):0.88 (e):0.77 (s), in keeping with the ratio of the percentages of domestic genome in the reference families used to build the corresponding maps, i.e., 1.00 (a):0.81 (e):0.50 (s). from further recombination frequencies reported in wild boars (in the ... | 1995 | 8536996 |
| renal venous architectonics in domestic swine. | renal venous architectonics were investigated in 240 kidneys from 120 swines at an age of 1-8 months. the methods used were: preparation, corrosion and x-ray examination. it was established that, in 75% of the cases, v. renalis cranialis and v. renalis caudalis were present. in the rest of the cases (25%), v. renalis intermedia was present. it was also observed that right and left renal veins formed distentions, which enveloped the caudal medial part of each adrenal gland. v. adrenalis (supraren ... | 1995 | 8546320 |
| morphological studies of the valves of the kidney vein in domestic swine. | it was established macroscopically that 37.5% of the renal veins investigated possess valves. valves were observed on both sides, but predominantly on the left side of the kidneys (14.58%). some valves were also observed in the main branches of the renal veins. the structure of the valves was studied with the use of light and electron microscopy. the most important finding was the observation of mast cells in the valves. this is probably a common biological phenomenon, since mast cells have been ... | 1995 | 8546321 |
| histomorphologic and histochemical characteristics of carpal glands (glandulae carpeae) in domestic swine (sus scrofa domesticus) and wild swine (sus scrofa ferus). | investigations were carried out on samples from carpal glands of domestic and wild swine of different ages. the anatomic position of carpal glands is identical in domestic and wild swine. glandular acini in domestic swine are bigger and more scarce than in wild swine. ldh activity is more intense in wild swine, while the activity of the investigated diaphorases is almost even. the activity alkaline and acid phosphatase is stronger in domestic swine, while the activity of non-specific esterases i ... | 1995 | 8546329 |
| effects of dexmedetomidine on coronary hemodynamics and myocardial oxygen balance. | alpha 2-adrenergic agonists decrease central sympathetic outflow and maintain normal transmural myocardial blood flow distribution, but intravenous bolus doses of these agents can also induce excessive coronary vasoconstriction and myocardial ischemia. the hypothesis of the present study was that a rapid intravenous bolus of dexmedetomidine, a specific alpha 2-adrenergic agonist, will cause coronary vasoconstriction and accompanying myocardial ischemia in young pigs. | 1995 | 8547552 |
| augmentation of coronary blood flow by ace inhibition: role of angiotensin and bradykinin. | inhibition of the angiotensin converting enzyme (ace) is known to enhance coronary blood flow via partial suppression of angiotensin ii and potentiation of bradykinin. the purpose of these experiments was to evaluate the contribution of each of these mechanisms to the ace inhibition induced changes in blood flow in myocardial regions perfused by intact or stenotic coronary arteries. seven domestic swine were submitted to an 82% stenosis of the left anterior descending artery with the circumflex ... | 1995 | 8556004 |
| a closed-chest porcine model of coronary dissection and thrombosis. | coronary dissection and thrombosis are important as pathophysiological mechanisms in acute coronary syndromes and as consequences of various interventional procedures. the present study was designed to develop and characterize a simple percutaneous method to produce coronary dissection and thrombosis in the pig. | 1995 | 8574461 |
| sustained-release local hirulog therapy decreases early thrombosis but not neointimal thickening after arterial stenting. | adventitial heparin delivery has been shown to inhibit thrombosis and neointimal thickening in a rat carotid injury model. to determine whether sustained, local delivery of hirulog, a potent antithrombin agent, inhibits thrombus formation and neointimal thickening after arterial stenting, silicone polymers containing hirulog were formulated at a concentration of 5.8% by weight and were tested in vitro to determine the rate of drug release. an oversized metallic stent was implanted in the carotid ... | 1996 | 8579010 |
| isolation of encephalomyocarditis virus from dormice (myoxus glis) in italy. | two isolates of encephalomyocarditis (emc) virus (zrc 276ra/90 and zrc 292ra/90) were isolated from two dormice (myoxus glis) in tuscany, italy. the two isolates were lethal for laboratory mice and caused a rapid cytopathic effect characterized by rounded and wrinkled cells in both baby hamster kidney cells (bhk21) and african green monkey kidney cells (vero). we found neutralizing antibodies against emc virus in 408 (77%) of 529 domestic pigs (sus scrofa scrofa) and in 165 (49%) of 338 wild boa ... | 1995 | 8583644 |
| consequences of selection on muscle composition. a comparative study on gracilis muscle in wild and domestic pigs. | european domestic pigs are derived from the european wild pig by genetic selection and differ in their muscular-growth ability. thus, it was the aim of this study to investigate the consequences of genetic selection on muscle composition and fibre size in the gracilis muscle. fibre typing based on the atpase reaction revealed that this muscle in wild pigs is composed mainly of type-i and -iia fibres, whereas, in domestic pigs, type-iib fibres were predominant. for all fibre types, domestic pigs ... | 1995 | 8588708 |
| classical swine fever in wild boar (sus scrofa)--experimental infections and viral persistence. | a pregnant wild boar and two wild boar weaners were inoculated intranasally with a field isolate of classical swine fever virus (csfv) recently derived from a diseased domestic pig. the clinical, pathological and haematological findings noted in the young wild boars were comparable to those in domestic weaner pigs inoculated with the same virus isolate. both wild boars showed the acute haemorrhagic form of csf, one animal died 18 days post inoculation (p. i.) and the second one had to be euthani ... | 1995 | 8591736 |
| morphological investigations of the glandulae profundae plicae semilunares conjuctivae in the domestic swine (sus scrofa domesticus) and the wild hog (sus scrofa ferus). | samples of glandulae profundae plicae semilunares (harderian glands) from five domestic swine and five wild hogs were used for this research. the gland samples were fixed in bouin solution and mounted in paraffin. the paraffin slices were stained with haematoxylin and eosin, according to the periodic-acid-schiff (pas) method, with alcian blue (ph 2.5), with toluidine blue (ph 4.0), and applying a combination of staining with alcian blue (ph 2.5) and the pas method. in domestic swine and wild hog ... | 1995 | 8592973 |
| peculiarities of the connection between mesangial and glomerular endothelial cells in the domestic-swine kidney. | the peculiarities of the connection between mesangial and endothelial cells are investigated in material from non-perfused swine kidneys. it is established that cytoplasm fragments of the endothelial cells, located between the mesangial angles, abruptly extend their size, and borders between them are difficult to discern. they possess single microvilli on their lumenal surface, some of which are highly corrugated, branched and fenestrated. in those parts, the mesangial-cell excrescences are tigh ... | 1995 | 8592974 |
| microscopical and ultrastructural studies of the renal artery in domestic swine. | both renal arteries from six, 8-month old, camborow hybrid pigs were examined in histological, semithin and ultrathin sections. it was established that the membrana elastica interna showed an expressed degree of wrinkliness. in certain sections, sometimes occupying 20% of the diameter of across-section, its curves were considerably higher and wider than those in the remaining part. the inner elastic membrane in these sections was cleaved in two layers. estates of lengthwise-situated smooth muscl ... | 1995 | 8592976 |
| [an outbreak of brucellosis in pigs and conclusions derived on the epidemiology of this animal disease]. | the examination of an outbreak of brucellosis in domestic pigs showed unambiguously the existence of a natural focus of infection in the population of wild boars. contrary to former assumptions persistence of br. suis, biovar 2, to occur mainly in the population of hares, evidently a change of hosts has taken place. possible cause might be a contrary development of the density of these wild animal populations. health control of wild animals should not be neglected, as it is an important part of ... | 1995 | 8593137 |
| [basic values of blood coagulation parameters in pigs (sus scrofa domesticus)]. | on 23 clinical healthy pigs (2-4 months of age, body weight 13-42 kg) under ketamin-pentobarbital anaesthesia blood plasma coagulation parameters have been investigated. to obtain basic values 26 parameters were measured: number of thrombocytes, parameters of thrombelastogram and resonance-thrombogram, prothrombin time, activated partial thromboplastin time, thrombin time, reptilase time, factors i, ii, v, vii, viii, x, antithrombin iii, plasminogen, alpha 1-antitrypsin, alpha 2-antiplasmin, alp ... | 1996 | 8593155 |
| serological study of pigs for antibody against african swine fever virus in two areas of southern malawi. | a serological survey was conducted in july 1991 on domestic pigs in two areas of southern malawi which were severely affected by the african swine fever (asf) epizootic in 1989-1991. sixty-six of the 216 owners questioned reported having witnessed asf in their pigs. forty-seven owners had pigs with antibodies against asf virus, and the overall prevalence of pigs with anti-asf virus antibodies was found to be 12.4%, in 445 pigs sampled in 35 villages. spread of asf was thought to occur principall ... | 1995 | 8593400 |
| spontaneous agonal respiration in a swine model of out-of-hospital cardiac arrest. | to describe ventilatory dynamics following the onset of ventricular fibrillation (vf) in an experimental swine model. | 1995 | 8597915 |
| the effect of prolonged pneumoperitoneum on renal function in an animal model. | prolonged, increased intra-abdominal pressure (iap) during laparoscopic surgery has been associated with oliguria and anuria. | 1996 | 8605555 |
| immunocytochemical studies on endocrine cells of alimentary tract of the pig in the embryonic and fetal period of life. | the study aimed at immunocytochemical analysis of alimentary tract endocrine cells between 20th day of embryonal life and 105th day of fetal life of domestic pig. in the pancreas, presence of endocrine cells was detected already in 20th day and, at the time, the cells comprised around 3/4 all cells in primordia of the organ. starting at that time, numerous endocrine cells produced insulin and glucagon and individual cells synthesized somatostatin and pancreatic polypeptide. in the 20th day, stom ... | 1995 | 8606027 |
| interferon, the oxytocin receptor and the maternal recognition of pregnancy in ruminants and non-ruminants: a comparative approach. | ruminant and non-ruminant members of the artiodactyla appear to use different mechanisms for the maternal recognition of pregnancy. in ruminants, the trophoblast of the developing blastocyst produces a characteristic type i interferon of the interferon-tau family; this acts by blocking endometrial synthesis of the oxytocin receptor. a similar mechanism applies to domestic ruminants (sheep, cow, goat) and deer. in roe deer, which have embryonic diapause and are monoestrus, there is no requirement ... | 1995 | 8606939 |
| myocardial cell death in reperfused and nonreperfused myocardial infarctions. mr imaging with dysprosioum-dtpa-bma in the pig. | to investigate whether dy-dtpa-bma-enhanced mr imagining would permit identification of myocardial cell death, myocardial infarction was induced in 12 domestic pigs. | 1996 | 8611317 |
| structure and organization of pig mhc class ii drb genes: evidence for genetic exchange between loci. | the pig major histocompatibility complex drb genes were studied by polymerase chain reaction (pcr) amplification of exon 2 from eight domestic pigs and two european wild boars. sequence comparisons together with a phylogenetic analysis showed the existence of at least three drb genes of which only one appears to be expressed. the two putative drb pseudogenes contained deletions in exon 2, making it possible to confirm the presence of three non-allelic drb genes by analyzing the length polymorphi ... | 1996 | 8613138 |
| hyperglycemia results in an increase in myocardial interstitial glucose and glucose uptake during ischemia. | the purpose of this investigation was to assess the effects of hyperglycemia, in the absence of changes in plasma insulin and arterial free fatty acid (ffa) levels, on interstitial glucose levels and glucose uptake across the left ventricular wall during ischemia in domestic swine. insulin secretion was suppressed with a continuous infusion of somatostatin. arterial ffa levels remained stable due to the suppression of insulin. microdialysis probes were used to estimate changes in interstitial gl ... | 1996 | 8622595 |
| iced temperature injectate for thermodilution cardiac output determination causes minimal effects on cardiodynamics. | controversy exists regarding the ideal injectate temperature for measuring cardiac output. iced temperature injectate gives a higher signal/noise ratio and less variability in the measured cardiac output. thus, less volume and fewer measurements are required. advocates of room temperature injectate have suggested that iced temperature injectate may perturb cardiodynamics. this concern has remained largely untested. to help resolve this controversy, we examined the effects of 5 ml iced injectate ... | 1996 | 8625640 |
| [zoo-anthroponoses in vojvodina. iv. epidemiologic characteristics of trichinosis in vojvodina]. | epidemiological characteristics of trichinellosis in vojvodina have been analyzed on the basis of registered cases of the disease, registration of epidemics and also epidemiological investigation of exposed persons. in the period 1984-1993, 1802 diseased persons were registered, 958 male and 844 female. death was registered in one case. average morbidity was 8.9/10(5). trichinellosis affects all age groups. at younger age the disease affects both sexes, but in the group over 20 years of age the ... | 1995 | 8657070 |
| comparison of self-expanding polyethylene terephthalate and metallic stents implanted in porcine iliac arteries. | comparison of the biocompatibility of self-expanding polyethylene terephthalate (pet) stents with self-expanding metallic stents (wallstents). | 1996 | 8661640 |
| controlled trial of laparoscopic-assisted vs open colon resection in a porcine model. | several series of laparoscopic colon resection have been reported in the literature with varied results; however, no controlled series of laparoscopic vs open colon resection has been reported. the purpose of this study was to determine the relative safety and adequacy of laparoscopic colon resection in a controlled trial using a porcine model. | 1996 | 8662429 |
| radiolabeled iododeoxyuridine: safety evaluation. | the emphasis of radiolabeled iododeoxyuridine (*iudr) research at our institution to date has been to assess its safety as a potential therapeutic agent. toward this goal, we have performed preclinical and clinical studies, using various routes of administration, to detect adverse changes in normal tissues in both humans and animals. as iudr is rapidly dehalogenated by the liver, the intravenous route is unlikely to be successful in therapeutic efforts. we have therefore focused our attention on ... | 1996 | 8676196 |
| splanchnic and peripheral tissue perfusion in experimental fat embolism. | to investigate the acute effects of experimental fat embolism on splanchnic and peripheral perfusion and oxygenation in pigs. | 1996 | 8681568 |
| myocardial dysfunction after successful resuscitation from cardiac arrest. | to investigate the functional and metabolic changes in the myocardium after successful resuscitation from cardiac arrest. | 1996 | 8681604 |
| experimental application of controlled limb reperfusion after incomplete ischaemia. | severe local and systemic complications may occur after revascularization of extremities exposed to prolonged complete or incomplete ischaemia. these complications may be reduced by controlling the reperfusate and the circumstances of the reperfusion period. ten adult german domestic pigs were exposed to 6 h of incomplete limb ischaemia by occlusion of the left iliac artery. to simulate the clinical situation of embolectomy, the occlusive snares were released after the ischaemic period in five p ... | 1996 | 8696746 |
| recent fusion events during evolution of pig chromosomes 3 and 6 identified by comparison with the babirusa karyotype. | the chromosomes of the babirusa, a species considered to have diverged from an ancestor of the pig during the miocene epoch, about 12-26 million years ago, were studied to determine the sites of recent rearrangements during evolution of the domestic pig. it is shown that there is a pericentric inversion of the entire short arm on pig chromosome 1, compared to its counterpart in the babirusa (chromosome 15). we also present evidence suggesting that pig chromosome 3 was derived by a telomere-centr ... | 1996 | 8697808 |
| [observational and experimental studies on relationship between domestic pigs and epidemic hemorrhagic fever investigation]. | observational and experimental studies on the relationship between domestic pigs and epidemic hemorrhagic fever (ehf) were carried out during 1986 to 1994 with reverse passive hemagglutination (rpha), reverse passive hemagglutination inhibition (rphi), horse-radish peroxidase-staphylococcal protein a (hrp-spa), indirect immunofluorescence assay (ifa) and reverse transcript polymerase chain reaction (rt-pcr) to understand the roles of domestic pigs played in the epidemic areas. results showed dom ... | 1995 | 8697938 |
| evaluation of the effects of autotransfusion of unprocessed blood on hemodynamics and oxygen transport in anesthetized pigs. | to examine the hemodynamic effects and the oxygen transport pattern of autotransfusion of unprocessed blood on hemodynamics and oxygen transportation. | 1996 | 8706465 |
| endotoxic shock alters distribution of blood flow within the intestinal wall. | to investigate whether a redistribution of blood flow from the mucosa to the muscular layer of the intestinal wall contributes to the observed increased arterial-mucosal pco2 gradient and the decreased mucosal tonometric ph during endotoxic shock. | 1996 | 8706490 |
| effects of graded doses of vasopressin on median fibrillation frequency in a porcine model of cardiopulmonary resuscitation: results of a prospective, randomized, controlled trial. | to assess the effects of graded doses of vasopressin vs. saline on median fibrillation frequency and defibrillation success in a porcine model of cardiopulmonary resuscitation. | 1996 | 8706492 |
| four alginate dressings in the treatment of partial thickness wounds: a comparative experimental study. | alginate-based absorption materials for wound treatment are meeting with increasing clinical acceptance. the purpose of this study was to compare four different calcium alginate dressings (algosteril, comfeel alginate, kaltostat and sorbsan) with respect to wound fluid retaining ability, adherence, dressing residues, epithelialisation and inflammatory cell infiltration using a standardised partial-thickness wound model in domestic pigs. wound fluid spread laterally onto surrounding normal skin b ... | 1996 | 8733355 |
| myocardial dysfunction after resuscitation from cardiac arrest: an example of global myocardial stunning. | this study investigated the effect of prolonged cardiac arrest and subsequent cardiopulmonary resuscitation on left ventricular systolic and diastolic function. | 1996 | 8752819 |
| an epidemiological study of influenza viruses among chinese farm families with household ducks and pigs. | to examine the possibility of interspecies transmission and genetic reassortment of influenza viruses on farms in southern china, we surveyed 20 farm families living outside the city of nanchang who raised pigs and ducks in their homes. weekly interviews of family members and virus isolation studies of throat swabs and faecal samples, collected from september 1992 to september 1993, established the seasonal pattern of respiratory tract infections in these families and identified 11 influenza vir ... | 1996 | 8760967 |
| age dependence of cerebrovascular response mechanisms in domestic pigs. | hypercapnia-induced cerebral vasodilation in the newborn pig is a prostanoid-associated response. in some adult models, hypercapnic cerebral vasodilation is associated with the generation of nitric oxide (no). acetylcholine (ach) produces a no-dependent cerebral vasodilation in many adult models, but topical ach is a prostanoid-associated cerebral vasoconstrictor in the newborn pig. we hypothesized that mediators influencing cerebral response can be age dependent. juvenile domestic pigs were com ... | 1996 | 8770094 |
| myocardial adaptation during and after sustained, demand-induced ischemia. observations in closed-chest, domestic swine. | we tested the hypotheses that prolonged, demand-induced myocardial ischemia plateaus and that on relief of stress, myocardial function remains depressed, with proportionate reductions in blood flow and oxygen consumption indicative of hibernation. | 1996 | 8772699 |
| a porcine model of chronic peripheral arterial occlusion. | to create a simple and reproducible model of chromic thrombosis for the evaluation of thrombolytic agents and devices. | 1996 | 8773977 |
| electromyographic and mechanomyographic characteristics of neuromuscular block by magnesium sulphate in the pig. | in spite of its well known propensity to cause accidental paralysis by a specific mechanism of action, mg(2+)-induced neuromuscular block has not been examined systematically for its characteristics of muscle response to nerve stimulation. we examined in seven anaesthetized domestic pigs the mechanomyographic (mmg) and neurally evoked compound electromyographic (ncemg, emg) responses of the tibialis anterior muscle to stimulation of its motor nerve, at baseline and during three levels of neuromu ... | 1996 | 8777111 |
| effects of hypercholesterolaemia on physiological recruitment of coronary vascular reserve in swine. | 1. the endothelium participates in the regulation of coronary vascular tone. as evidence exists from studies performed on epicardial vessels that hypercholesterolaemia impairs endothelial function, we tested the hypothesis that hypercholesterolaemia impairs coronary vascular reserve in an intact animal. 2. domestic swine, maintained on a regular (n = 9) or a 2% high-cholesterol (n = 9) diet for 3 months were instrumented with a catheter in the left atrium for microsphere injection, a catheter in ... | 1996 | 8777832 |
| alternative methods of exposure minimize cardiopulmonary risk in experimental animals during minimally invasive surgery. | alternative methods of exposure are needed for minimally invasive surgery to avoid hypercarbia and acidosis associated with carbon dioxide (co2) abdominal insufflation. the goals of this study were to determine the pulmonary and hemodynamic effects of both helium (he) abdominal insufflation and placement of a mechanical abdominal wall-lifting device (lifter) during laparoscopy. | 1996 | 8779063 |
| sus scrofa domestica endoparasitic resistance in the amazonas. | the domestic pig (sus scrofa domestica l.) has been wild breeding in the varzea amazonian estuary area. without dietary supplement or medical prevention, the pigs survive, bringing economic benefits to local peasants. endoparasitic diseases generate economic losses because of neonatal death and clinical disease. we assessed the nematoda (o. nematoda) and coccidia (o. eucoccidia) parasitic level and tolerance in 75 pigs (0-18 months) from 35 families using the following methods: (i) larvae cultur ... | 1996 | 8784532 |
| immunocytochemical distribution of catecholamine-synthesizing neurons in the hypothalamus and pituitary gland of pigs: tyrosine hydroxylase and dopamine-beta-hydroxylase. | this study describes the distribution of catecholaminergic neurons in the hypothalamus and the pituitary gland of the domestic pig, sus scrofa, an animal that is widely used as an experimental model of human physiology in addition to its worldwide agricultural importance. hypothalamic catecholamine neurons were identified by immunocytochemical staining for the presence of the catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine-beta-hydroxylase. tyrosine hydroxylase-immunoreacti ... | 1996 | 8789282 |
| effects of intracoronary carbon dioxide on left ventricular function in swine. | carbon dioxide is currently used as an arterial and venous contrast agent; however, little is known of its effects on left ventricular function. this study was undertaken to investigate those effects. | 1996 | 8790949 |
| increased concentrations of endothelin-1 messenger rna in tissues and endothelin-1 peptide in plasma in septic pigs: modulation by betamethasone. | to study the expression of preproendothelin-1 messenger rna (mrna) in tissue after escherichia coli lipopolysaccharide challenge and to evaluate the possible effects of betamethasone both regarding endothelin-1 production as well as hemodynamic and vascular effects during e. coli lipopolysaccharide infusion in pigs in vivo. | 1996 | 8797627 |
| heritability estimate of hypertrophic cardiomyopathy in pigs (sus scrofa domestica). | the purpose of this study was to evaluate the heritability of hypertrophic cardiomyopathy (hcm) in pigs and the relation between hcm and heart measurements, pathologic features, and growth to provide references for hcm line development. a total of 353 on-farm tested gilts (females) and boars (males) from 74 sire families were randomly selected from a single breeding farm where hcm was prevalent. hearts were collected after animals were slaughtered. heart length, width, and weight, heart-to-body ... | 1996 | 8799938 |
| the immunogenic and pathogenic potential of short poly(c) tract mengo viruses. | we have shown previously that genetically engineered mengo viruses with artificial deletions in their 5' noncoding polyribocytidylic acid (poly(c)) tracts are highly attenuated for the natural murine host and also for other animals such as baboons, macaques, and domestic pigs. the present report further characterizes select short poly(c) tract mengo viruses in the natural murine host. a positive correlation was found between the length of the poly(c) tract and murine virulence, as measured by vi ... | 1996 | 8806569 |
| geographic population structure and sequence divergence in the mitochondrial dna control region of the japanese wild boar (sus scrofa leucomystax), with reference to those of domestic pigs. | mitochondrial dna (mtdna) control regions from 40 japanese wild boars were examined by direct sequencing after amplification by pcr. from the dna sequences obtained, we found eight haplotypes, whose differences arose via transitions. the geographical distribution of these different haplotypes indicated that wild boar populations inhabited limited areas and that there was some restricted gene flow between local populations. eight mtdna haplotypes from eastern and western domestic pigs and the ryu ... | 1996 | 8813051 |
| an outbreak of japanese encephalitis in the torres strait, australia, 1995. | to determine the distribution of virus infection during an outbreak of japanese encephalitis (je) in the torres strait, and to describe the environmental factors facilitating the outbreak. | 1996 | 8816682 |
| serum concentrations of melatonin in prepubertal gilts exposed to either constant or stepwise biweekly alteration in scotophase. | melatonin (mel), a hormone known to mediate photoperiodic cues, is secreted from the pineal gland in a circadian fashion in numerous species. the transduction of photoperiodic information into the secretion of mel, however, remains controversial in the pig. to determine whether domestic pigs have a nocturnal increase in serum melatonin when exposed to equatorial photoperiods only, 24 prepubertal gilts (38.7 +/- 0.7 kg; 104.5 +/- 0.8 d) and 12 mature ewes, serving as positive controls, were rando ... | 1996 | 8839625 |
| characterisation of bradykinin receptors from juvenile pig coronary artery. | coronary artery rings from juvenile male farm pigs were incubated for 6 h and precontracted with u46619. the rings relaxed in response to des-arg9-bradykinin (pd2, 7.78 +/- 0.13; emax, 87.4 +/- 4.3%) and to bradykinin (pd2, 8.69 +/- 0.30; emax, 104.2 +/- 4.4%). these responses were abolished by endothelium removal and unaffected by indomethacin whilst ng-nitro-l-arginine reduced the relaxation due to des-arg9-bradykinin only. preincubation with cycloheximide or actinomycin had no effect against ... | 1996 | 8851166 |
| protection of non-murine mammals against encephalomyocarditis virus using a genetically engineered mengo virus. | genetically engineered mengo viruses with artificial deletions in the 5' noncoding poly(c) tracts are highly attenuated for pathogenicity when introduced as live vaccines into the natural murine host. inoculation produces lifelong protective immunity without disease or viral persistence. this report extends the vaccination studies to non-murine hosts, including baboons, macaques and domestic pigs, all of which are susceptible to severe cardiovirus epizootics. all animals of these species that we ... | 1996 | 8852413 |
| a comparison of the pathophysiologic effects of carbon dioxide, nitrous oxide, and helium pneumoperitoneum on intracranial pressure. | previous studies have suggested that diagnostic laparoscopy may be contraindicated in multiple trauma patients with closed head injuries because of the detrimental effects of carbon dioxide (co2) pneumoperitoneum on intracranial pressure (icp). in this study we compared the effects of two alternative inflation gases, helium (he) and nitrous oxide (n2o), against the standard agent used in most hospitals, co2. icp was monitored in experimental animals both with and without a space occupying intrac ... | 1996 | 8862077 |
| the soft tissue cover of the mandibular condyle: age-related changes in high buoyant density proteoglycans, free tissue water and remodelling activity. | age-related changes in the relative proportion of high buoyant density proteoglycans of the soft tissue cover of the mandibular condyle of domestic pigs and the chemical composition of these proteoglycans were investigated by biochemical methods. the relative proportion of high buoyant density proteoglycans has been shown to decrease with age, with their chemical composition varying as follows: with age, the relative proportions of protein increased, galactosamine decreased, glucosamine was simi ... | 1996 | 8874176 |
| starling resistor effects on pulmonary artery occlusion pressure in endotoxin shock provide inaccuracies in left ventricular compliance assessments. | assessment of left ventricular preload and left ventricular compliance changes in septic shock using pulmonary artery occlusion pressure (paop) presumes that this pressure accurately reflects left heart filling pressure. we tested the hypothesis that starling resistor forces render paop inaccurate as an index of left heart filling pressure, resulting in misleading assessments of left ventricular compliance changes. | 1996 | 8874296 |
| the prepubertal ontogeny of luteinizing hormone releasing hormone-like immunoreactivity in the diencephalon and telencephalon of the male meishan pig brain. | luteinizing hormone releasing hormone (lhrh) is a decapeptide that regulates reproductive function and behaviors in mammalian species. because of the importance of proper reproductive function and efficiency in agricultural species, we have investigated the prepubertal ontogeny of lhrh-like immunoreactivity (ir) in the male meishan pig. the meishan is a chinese breed known for reproductive traits including increased litter size and precocious puberty, but slow growth and obesity. brains of anima ... | 1996 | 8874890 |
| transorbital approach to the porcine pituitary. | a transorbital approach to the pituitary gland is described in domestic swine weighing between 40 and 70 kg. a transpalpebral eye exenteration is performed and the optic canal is enlarged caudally, using a bone drill. an operating microscope is used to improve visualization of the surgical site as the pituitary stalk and anterior pituitary are exposed to the level of the optic chiasm. this approach exposes the pituitary sufficiently to perform either a hypophyseal stalk transection or a hypophys ... | 1996 | 8887068 |
| effectiveness of fibrin glue in the reduction of postoperative intrapericardial adhesions. | the hemostatic properties of fibrin sealant have been well described. previously published reports have attempted to clarify the possible role of fibrin glue in the inhibition of the formation of intrapericardial adhesions following cardiac surgery. earlier work hypothesized that fibrin glue may reduce the severity of postoperative adhesions and that the use of autologous fibrin glue may have similar effects, without the risks that accompany homologous blood products. six juvenile farm pigs were ... | 1996 | 8887071 |
| isolated coronary artery transplantation in pigs: a new model to study transplantation arteriosclerosis and humoral rejection. | graft atherosclerosis is a major cause of death after heart transplantation; its causes are multifactorial and poorly understood. to determine whether specific sensitization to coronary artery antigens is a contributing factor, we developed an isolated coronary artery allotransplantation model in pigs. | 1996 | 8889988 |
| location of external anal sphincter motoneurons in the sacral cord of the female domestic pig. | the location of the striated external anal sphincter motoneurons in the spinal cord was investigated in 12, between 3 and 4 months old, female domestic pigs using the retrograde tracer horseradish peroxidase (hrp). their motoneuronal cell bodies were found in the spinal segments s1-s3, and were not located in the ventral horn, but dorsolateral to the central canal. this location within the spinal gray matter strongly differs from the location of the external and sphincter motoneurons in rat, cat ... | 1996 | 8897493 |
| repair of a mid-diaphyseal femoral fracture in a boar. | a simple, oblique fracture of the middle portion of the diaphysis of the right femur was successfully repaired in a 10-month-old 150-kg berkshire boar, using a 4.5-mm 9-hole broad dynamic compression plate applied to the lateral surface of the bone. a lateral surgical approach provided excellent access to the fragment ends. intravenous administration of atracurium besylate facilitated traction along the long axis of the bone and fracture reduction. the plate was luted with 5% gentamicin sulfate- ... | 1996 | 8899028 |
| neonatal hemodynamic responses to extreme ranges of controlled graded hypoxia. | to determine the hemodynamic responses to a wide range of specific, controlled, graded levels of hypoxic hypoxia over 120 mins in a neonatal porcine model and to identify the pao2 threshold for altered hemodynamic homeostasis. | 1996 | 8917041 |
| husbandry and diseases of captive wild swine and peccaries. | wild swine and peccaries are popular exhibit animals throughout the world, but the anatomy and behaviour of these species make it difficult to construct housing and enclosures which are suitable from an aesthetic and sanitation standpoint. african wild suids may serve as reservoir hosts for african swine fever. likewise, african suids are susceptible to most of the viral, bacterial and parasitic diseases of domestic swine. wild swine and peccaries are not an important source of zoonotic diseases ... | 1996 | 8924700 |
| a karyotypic analysis of the lesser malay chevrotain, tragulus javanicus (artiodactyla: tragulidae). | chevrotains are small forest-dwelling ruminants of the family tragulidae. the chromosome number of the lesser malay chevrotain was determined to be 2n = 32, nf = 64, g- and q-banding allowed the identification of homologous chromosomes, and c-banding demonstrated the presence of pericentromeric, telomeric and interstitial constitutive heterochromatin. q-band comparisons with domestic cattle revealed relatively few monobrachial chromosome band homologies. however, the smallest biarmed autosome of ... | 1996 | 8939367 |
| the continent sigmoid urinary reservoir--an experimental study in pigs. | to evaluate the function of a continence mechanism in combination with a colonic urinary reservoir in a pig model. | 1996 | 8944507 |
| increased cardiac fatty acid uptake with dobutamine infusion in swine is accompanied by a decrease in malonyl coa levels. | malonyl coa is an important regulator of fatty acid oxidation in the heart secondary to its ability to inhibit carnitine palmitoyltransferase 1 (cpt 1). malonyl coa is produced from acetyl coa in a reaction catalyzed by acetyl coa carboxylase (acc). in this study we determined if alterations in malonyl coa regulation of fatty acid metabolism are involved in the increase in energy transduction seen following an increase in cardiac work. | 1996 | 8944819 |
| histopathologic appearance of arterial occlusions with hydrogel and polyvinyl alcohol embolic material in domestic swine. | this study observes the histologic changes resulting from a hydrogel embolic agent (polyacrylonitrile [pan]) compared with polyvinyl alcohol particles (pva) of similar size. | 1996 | 8951758 |
| impaired bronchial healing after lung donation from non-heart-beating donors. | bronchial viability after lung transplantation remains a concern. modern preservation methods, surgical technique, and limited cold ischemic periods have decreased the frequency of bronchial complications. however, lungs procured from non-heart-beating donors are subjected to a mandatory period of warm ischemia. we investigated bronchial healing in a porcine survival model of left lung transplantation using organ procurement from non-heart-beating donors after a 60-minute period of warm ischemia ... | 1996 | 8956117 |
| effects of left heart assist on geometry and function of the interventricular septum. | right ventricular (rv) dysfunction is a common but poorly understood problem associated with mechanical left heart assist (lha). left ventricular unloading may affect rv function even in normal hearts by altering geometry or function of the interventricular septum, although such changes have not been well defined. accordingly, the purposes of this study were to quantify the effects of lha on septal geometry and function in normal swine and to assess the resultant effects on rv function. | 1996 | 8957382 |
| cardiovascular function during the postresuscitation phase after cardiac arrest in pigs: a comparison of epinephrine versus vasopressin. | the administration of vasopressin during cardiopulmonary resuscitation (cpr) provides significantly more vital organ blood flow when compared with epinephrine during cardiac arrest in pigs. the effects of this potent vasoconstrictor on postresuscitation cardiovascular function remain unknown. the purpose of this study was to compare the effects of vasopressin and epinephrine on cardiovascular function in the postresuscitation phase after cpr. | 1996 | 8968270 |
| an ikappab homolog encoded by african swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages. | cytokines stimulate inflammatory defenses against viral infections. in order to evade host defenses, viruses have developed strategies to counteract antiviral cytokines. african swine fever virus (asfv) is a large, double-stranded dna virus that infects macrophages. this study demonstrates that asfv effectively inhibited phorbol myristic acid-induced synthesis of antiviral, proinflammatory cytokines alpha interferon, tumor necrosis factor alpha, and interleukin-8 in infected macrophages as asses ... | 1996 | 8970976 |
| nadph-diaphorase expression of endothelial cells during four weeks' healing of a stretch-eptfe graft: an experimental porcine study. | endothelial nitric oxide synthase (enos) mediates the conversion of l-argine to no and citrulline, which requires nicotinamide adenine dinucleotide phosphate (nadph) as an essential cofactor. evidence has been given that nos accounts for the nadph-diaphorase activity. the aim of the present study was to identify the histochemical and immunocytochemical appearance of nadph-diaphorase and von willebrand factor (factor viii) respectively, in endothelial cells (ecs) during healing of stretch-expande ... | 1996 | 8971580 |
| comparative ureteral microanatomy. | several animals have been used as models for experimental upper urinary tract surgery. although minipigs have recently gained favor because their upper urinary tract is grossly similar to that of humans, the ureteral microanatomic features of the two species have not been compared. we evaluated the histologic features of human and animal ureters in order to provide addition information regarding experimental models for upper urinary tract surgery. cross-sections of upper, middle, and lower urete ... | 1996 | 8972786 |
| ectopic locations of taenia saginata asiatica cysticerci in the abdominal cavity of domestic pig and monkey. | eleven small-ear-miniature pigs, 1 landrace small-ear-miniature pig, and 1 monkey (macaca cyclopis) were infected experimentally with eggs of taenia saginata asiatica. they were found to harbor cysticerci on the liver surface, each with a thin, whitish fiber connecting to another location in the same lobe, or to other lobes of the liver; some were also connected individually to the diaphragm, abdominal muscles, and gall bladder with a short, thin fiber. moreover, they also harbored extrahepatic ... | 1996 | 8973419 |
| intracerebroventricular porcine corticotropin-releasing hormone and cortisol effects on pig immune measures and behavior. | the effects of intracerebroventricular (icv) administration of porcine corticotropin-releasing hormone (pcrh) and cortisol on the immune system and behavior were examined in domestic pigs. in experiment 1, 50 micrograms of pcrh in 200 microliters of saline or 200 microliters of vehicle was administered i.c.v. at 0600 h. blood samples were obtained at 0600 (prior to injection), 0700, and 0800 h. plasma cortisol concentrations were higher at 1 and 2 h after pcrh than after saline. generally, pcrh ... | 1997 | 8976528 |
| sensitivity and behavioral responses to the pheromone androstenone are not mediated by the vomeronasal organ in domestic pigs. | based largely on results of studies of laboratory rodents, the vomeronasal or accessory olfactory system is believed to function mainly in social communication, mediating the effects of stimuli such as urine or glandular secretions on the behavior or endocrine response of conspecifics. in the domestic pig (sus scrofa), the steroid androstenone has been identified as a pheromone that facilitates expression of both attraction to the male and a receptive mating stance in estrous females. though the ... | 1997 | 8980852 |
| localization of landmarks and bands in the karotype of sus scrofa domestica. comparison between different classifications. | representative rbg-banded chromosomes of sus scrofa domestica and diagrammatic representation of the banding patterns at the 600 band stage are presented. comparison between different classification systems has been performed. it is suggested that the data presented can be applied to gene mapping, localization of chromosome aberrations, comparative cytogenetics, and translation between different classification systems. | 1995 | 8984097 |
| [recent data on the epidemiology of japanese encephalitis]. | japanese encephalitis is an arbovirosis the incidence and geographic distribution of which are increasing in rural areas of tropical and temperate asia. a total of about 45,000 to 50,000 clinical cases occur annually. the flavivirus responsible for the disease shows birds as usual hosts, and culex mosquitoes as vectors. after a first amplification cycle in birds, the virus can be transmitted to domestic pigs, then to man. this scheme, however, shows large variations in the different regions, acc ... | 1996 | 8991613 |
| chromosome homology between the domestic pig and the babirusa (family suidae) elucidated with the use of porcine painting probes. | homology among three pairs of domestic pig (sus scrofa) and five pairs of babirusa (babyrousa babyrussa) autosomes has been demonstrated with the use of porcine painting probes. with the results of this study, in addition to data obtained earlier through the application of banding techniques, correspondence between all individual chromosomes of these two distantly related pigs has been identified. | 1996 | 8995485 |
| a comparative study of three occlusive dressings in the treatment of full-thickness wounds in pigs. | little objective information is available on the influence of occlusive dressings on the healing of cutaneous full-thickness wounds. | 1997 | 8996261 |
| [social dominance and rank relationships in domestic pigs: a critical review]. | viewing dominance as an attribute of repeated agonistic interactions between two individuals, the present paper reviews theoretical approaches towards concepts of dominance, methods of measurement, and basic principles and problems connected with social dominance in domestic pigs. domestic pigs are able to establish social organization structures during all stages of their ontogeny. according to definition, dominance relationships occur when a consistent asymmetry of the result of dyadic agonist ... | 1996 | 8999780 |
| the effects of desflurane on splanchnic hemodynamics and oxygenation in the anesthetized pig. | this study was designed to investigate the effects of desflurane on systemic and splanchnic hemodynamics, o2 delivery and o2 uptake, tissue oxygenation (as monitored by surface po2 electrodes), and hepatic oxygen-dependent intermediary metabolism (hepatic lactate uptake, intestinal lactate production, ketone-body ratio) in the pig. we studied 11 anesthetized (i.e., ketamine, flunitrazepam, vecuronium) and ventilated domestic pigs (17-23 kg). after instrumentation, desflurane was administered ran ... | 1997 | 9024014 |
| spectral analysis of ventricular fibrillation and closed-chest cardiopulmonary resuscitation. | this study was designed to assess the interference by closed-chest cardiopulmonary resuscitation (cpr) on the ventricular fibrillation (vf) ecg signal in a porcine model of cardiac arrest and to elucidate which variable of vf spectral analysis reflects best myocardial blood flow and resuscitation success during cpr. fourteen domestic pigs were allocated to receive either 0.4 u/kg vasopressin (n = 7) or 10 ml saline (n = 7) after 4 min of vf and 3 min of cpr. using radiolabeled microspheres, myoc ... | 1996 | 9025132 |
| successful transplantation of lungs topically cooled in the non-heart-beating donor for 6 hours. | the aim of this study was to transplant lungs that had been topically cooled in the non-heart-beating donor for 6 hours, using the most challenging evaluation method possible, namely single-lung transplantation followed by immediate contralateral pneumonectomy. | 1997 | 9033298 |
| occlusive mesenteric ischemia and its effects on jejunal intramucosal ph, mesenteric oxygen consumption and oxygen tensions from surfaces of the jejunum in anesthetized pigs. | to investigate the effects of superior mesenteric artery (sma) flow reduction on the jejunal intramucosal ph (phi) and to compare these effects with corresponding changes of mesenteric oxygen transport variables and oxygen tensions on the surfaces of the jejunal serosa and mucosa. | 1997 | 9037646 |
| biomembrane permeation of nicotine: mechanistic studies with porcine mucosae and skin. | in the present study, the permeation and partitioning of nicotine as a function of ph was investigated with various regions of skin and absorptive mucosae that were freshly excised from domestic pigs. as an ionizable compound (pka values of 3.04 and 7.84), nicotine in solutions of different ph values provides a model for determining the influence of the charge status of a molecule on permeation. the permeation of nicotine across porcine mucosae and skin followed zero-order kinetics. the rate of ... | 1997 | 9040106 |
| the effects of progressive anemia on jejunal mucosal and serosal tissue oxygenation in pigs. | anemia may promote intestinal hypoxia. we studied the effects of progressive isovolemic hemodilution on jejunal mucosal (po2muc), and serosal tissue oxygen tension (po2ser, clark-type surface electrodes), mucosal microvascular hemoglobin oxygen saturation (hbo2muc), and hematocrit (hctmuc; tissue reflectance spectophotometry) in a jejunal segment. twelve domestic pigs were anesthetized, paralyzed, and mechanically ventilated. laparatomy was performed, arterial supply of a jejunal segment isolate ... | 1997 | 9052297 |