| over two decades of plasmodium knowlesi infections in sarawak: trend and forecast. | malaria is still of great public health concern, especially in malaysian borneo. the aim of this study was to determine the trends of p. knowlesi infection in sarawak, malaysia and to forecast the incidence of p. knowlesi until the year 2040. data on p. knowlesi malaria cases from 1992 to the year 2014 were obtained from the sarawak health department, malaysia. arima model was applied to forecast the future incidence of p. knowlesi infection. the data for the whole of sarawak and subsequently th ... | 2017 | 28768148 |
| individual-level factors associated with the risk of acquiring human plasmodium knowlesi malaria in malaysia: a case-control study. | the emergence of human malaria due to the monkey parasite plasmodium knowlesi threatens elimination efforts in southeast asia. changes in land use are thought to be driving the rise in reported p knowlesi cases, but the role of individual-level factors is unclear. to address this knowledge gap we assessed human and environmental factors associated with zoonotic knowlesi malaria risk. | 2017 | 28758162 |
| pacbio assembly of a plasmodium knowlesi genome sequence with hi-c correction and manual annotation of the sicavar gene family. | plasmodium knowlesi has risen in importance as a zoonotic parasite that has been causing regular episodes of malaria throughout south east asia. the p. knowlesi genome sequence generated in 2008 highlighted and confirmed many similarities and differences in plasmodium species, including a global view of several multigene families, such as the large sicavar multigene family encoding the variant antigens known as the schizont-infected cell agglutination proteins. however, repetitive dna sequences ... | 2017 | 28720171 |
| evaluation of electric nets as means to sample mosquito vectors host-seeking on humans and primates. | plasmodium knowlesi is found in macaques and is the only major zoonotic malaria to affect humans. transmission of p. knowlesi between people and macaques depends on the host species preferences and feeding behavior of mosquito vectors. however, these behaviours are difficult to measure due to the lack of standardized methods for sampling potential vectors attracted to different host species. this study evaluated electrocuting net traps as a safe, standardised method for sampling p. knowlesi vect ... | 2017 | 28720113 |
| strict tropism for cd71+/ cd234+ human reticulocytes limits plasmodium cynomolgi's zoonotic potential. | two malaria parasites of southeast asian macaques, plasmodium knowlesi and p. cynomolgi, can infect humans experimentally. in malaysia, where both species are common, zoonotic knowlesi malaria has recently become dominant, and cases are recorded throughout the region. by contrast, to date only a single case of naturally acquired p. cynomolgi has been found in humans. in this study we show that whereas p. cynomolgi merozoites invade monkey red blood cells (rbcs) indiscriminately in vitro, for hum ... | 2017 | 28698207 |
| plasmodium knowlesi malaria in a traveller returning from the philippines to italy, 2016. | plasmodium knowlesi is a simian parasite responsible for most human cases of malaria in malaysian borneo. a timely recognition of infection is crucial because of the risk of severe disease due to the rapid increase in parasitemia. we report a case of p. knowlesi infection in a traveller who developed fever and thrombocytopenia after returning from the philippines in 2016. rapid antigen test was negative, microscopy examination showed parasites similar to plasmodium malariae, with a parasite coun ... | 2017 | 28675245 |
| genetic diversity in the c-terminus of merozoite surface protein 1 among plasmodium knowlesi isolates from selangor and sabah borneo, malaysia. | plasmodium knowlesi, a malaria parasite of macaques, has emerged as an important parasite of humans. despite the significance of p. knowlesi malaria in parts of southeast asia, very little is known about the genetic variation in this parasite. our aim here was to explore sequence variation in a molecule called the 42kda merozoite surface protein-1 (msp-1), which is found on the surface of blood stages of plasmodium spp. and plays a key role in erythrocyte invasion. several studies of p. falcipar ... | 2017 | 28634105 |
| guest commentary: plasmodium knowlesi-need to diagnose in india. | | 2017 | 28459008 |