| mycobiota and mycotoxins in bee pollen collected from different areas of slovakia. | contamination by microscopic fungi and mycotoxins in different bee pollen samples, which were stored under three different ways of storing as freezing, drying and uv radiation, was investigated. during spring 2009, 45 samples of bee-collected pollen were gathered from beekeepers who placed their bee colonies on monocultures of sunflower, rape and poppy fields within their flying distance. bee pollen was collected from bees' legs by special devices placed at the entrance to hives. samples were ex ... | 2011 | 21749250 |
| the slt2 mitogen-activated protein kinase-mediated signalling pathway governs conidiation, morphogenesis, fungal virulence and production of toxin and melanin in the tangerine pathotype of alternaria alternata. | fungi respond and adapt to different environmental stimuli via signal transduction systems. we determined the function of a yeast slt2 mitogen-activated protein (map) kinase homologue (aaslt2) in alternaria alternata, the fungal pathogen of citrus. analysis of the loss-of-function mutant indicated that aaslt2 is required for the production of a host-selective toxin, and is crucial for fungal pathogenicity. moreover, the a. alternata slt2 mutants displayed hypersensitivity to cell wall-degrading ... | 2011 | 21726368 |
| influence of water activity and temperature on growth and mycotoxin production by alternaria alternata on irradiated soya beans. | the aim of this study was to determine the effects of water activity (a(w)) (0.99-0.90), temperature (15, 25 and 30-¦c) and their interactions on growth and alternariol (aoh) and alternariol monomethyl ether (ame) production by alternaria alternata on irradiated soya beans. maximum growth rates were obtained at 0.980 a(w) and 25-¦c. minimum a(w) level for growth was dependent on temperature. both strains were able to grow at the lowest a(w) assayed (0.90). maximum amount of aoh was produced at 0 ... | 2011 | 21737171 |
| characterization of the skin fungal microbiota in patients with atopic dermatitis and healthy subjects. | patients with atopic dermatitis (ad) are highly susceptible to viral, bacterial, and fungal skin infections because their skin is dry, which are involved in the barrier function of the skin. therefore, the skin microbiota of patients with ad is believed to be different from that of healthy individuals. in the present study, we compared the skin fungal microbiota of nine patients with mild, moderate, or severe ad and ten healthy subjects using an rrna clone library. fungal d1/d2 large subunit (ls ... | 2011 | 21699559 |
| the pattern of sensitisation to inhalant allergens in omani patients with asthma, allergic rhinitis and rhinoconjunctivitis. | identification of relevant allergens that are prevalent in each environment which may have diagnostic and therapeutic implications in allergic diseases. this study aimed to identify the pattern of sensitisation to inhalant allergens in omani patients with asthma, allergic rhinitis and rhinoconjunctivitis. | 2008 | 21748078 |
| the effect of nano-silver on the activation of nasal polyp epithelial cells by alternaria, der p1 and staphylococcal enterotoxin b. | nano-silver is used for its anti-bacterial, anti-viral and anti-fungal properties. the aim of this study was to investigate the potential clinical efficacy of nano-silver for its anti-inflammatory effect on respiratory epithelial cell inflammation. primary nasal polyp epithelial cells (npecs) were exposed to alternaria alternata, der p1, and staphylococcal enterotoxin b for 48h with or without various concentration of nano-silver, then the supernatants were collected. cell cytotoxicities were me ... | 2011 | 21683166 |
| the synthetic strigolactone gr24 influences the growth pattern of phytopathogenic fungi. | strigolactones that are released by plant roots to the rhizosphere are involved in both plant symbiosis with arbuscular mycorrhizal fungi and in plant infection by root parasitic plants. in this paper, we describe the response of various phytopathogenic fungi to the synthetic strigolactone gr24. when gr24 was embedded in the growth medium, it inhibited the growth of the root pathogens fusarium oxysporum f. sp. melonis, fusarium solani f. sp. mango, sclerotinia sclerotiorum and macrophomina phase ... | 2011 | 21688170 |
| induction of mucin and muc5ac expression by the protease activity of aspergillus fumigatus in airway epithelial cells. | allergic bronchopulmonary mycosis, characterized by excessive mucus secretion, airflow limitation, bronchiectasis, and peripheral blood eosinophilia, is predominantly caused by a fungal pathogen, aspergillus fumigatus. using dna microarray analysis of nci-h292 cells, a human bronchial epithelial cell line, stimulated with fungal extracts from a. fumigatus, alternaria alternata, or penicillium notatum, we identified a mucin-related muc5ac as one of the genes, the expression of which was selective ... | 2011 | 21685325 |
| microbial transformation of deoxyandrographolide by alternaria alternata as 3.4578. | biotransformation of deoxyandrographolide (1) by alternaria alternata as 3.4578 gave five derivatives identified by spectral methods including 2d nmr as the known dehydroandrographolide (2) and 9beta-hydroxy-dehydroandrographolide (3) and the new compounds 9beta-hydroxy-deoxyandrographolide (4), 3alpha,17,19-trihydroxy-8,13-ent-labdadien-15,16-olide (5) and 3-oxo-9beta-hydroxy-deoxyandrographolide (6). | 2011 | 21815410 |
| manipulation of heterogeneity product in 4'-demethylepipodophyllotoxin biotransformation process by using yeast extract as nitrogen source. | manipulation of product heterogeneity was attempted by using yeast extract as nitrogen source in alternaria alternata s-f6 transformation process of 4'-demethylepipodophyllotoxin. when the nitrogen source of nano(3) was replaced by yeast extract, the heterogeneity of biotransformation products was significantly varied from a single product (i.e., 4'-demethylpodophyllotoxone) to four podophyllum derivates. according to the kinetics of 4'-demethylepipodophyllotoxin biotransformation process by a. ... | 2011 | 21706170 |
| characterization of new alternaria alternata-specific rat monoclonal antibodies. | in this study, three different rat hybridoma cell lines secreting monoclonal antibodies (mabs) recognizing the spores from alternaria alternata, a plant pathogenic fungus, contaminant of food products and important cause of both allergic rhinitis and asthma, have been characterized. these three mabs are all of igm isotype. two antibodies, a1 and f10, were cross-reactive antibodies recognizing spores from alternaria, cladosporium, penicillium, aspergillus and stachybotrys genera, but not the yeas ... | 2011 | 21892786 |
| indoor exposure to mould allergens. | humid indoor environments may be colonised by allergenic filamentous microfungi (moulds), aspergillus spp., penicillium spp., cladosporium spp., and alternaria spp. in particular. mould-induced respiratory diseases are a worldwide problem. in the last two decades, mould allergens and glucans have been used as markers of indoor exposure to moulds. recently, mould allergens alt a 1 (alternaria alternata) and asp f 1 (aspergillus fumigatus) have been analysed in various environments (residential an ... | 2011 | 22202471 |
| assessment of home environments with a fungal index using hydrophilic and xerophilic fungi as biologic sensors. | abstract previously, the author proposed a 'fungal index' that quantifies the capacity for fungal growth in a test environment where a device (fungal detector) encapsulating spores of a xerophilic sensor fungus eurotium herbariorum was placed. it was also found that an extremely xerophilic fungus, aspergillus penicillioides, was suitable as a sensor fungus at sites with lower relative humidity (rh). in this report, the hydrophilic fungus alternaria alternata was added to sensor fungi for the de ... | 2011 | 21995759 |
| Mycogenesis of gold nanoparticles using a phytopathogen Alternaria alternata. | The development of an eco-friendly and reliable process for the synthesis of gold nanomaterials (AuNPs) using microorganisms is gaining importance in the field of nanotechnology. In the present study, AuNPs have been synthesized by bio-reduction of chloroauric acid (HAuCl(4)) using the fungal culture filtrate (FCF) of Alternaria alternata. The synthesis of the AuNPs was monitored by UV-visible spectroscopy. The particles thereby obtained were characterized by UV, dynamic light scattering (DLS), ... | 2011 | 22009439 |
| Antioxidant and antifungal potential of methanol extracts of Phellinus spp. from Sonora, Mexico. | BACKGROUND: Among the potential natural sources of bioactive compounds the macroscopic fungi Phellinus spp. are evidenced by previous prospection. Phenolic compounds are among the major antioxidant and antimicrobial contributors to their bioactive properties. OBJECTIVE: The goal of this study was to determine the total phenolic and flavonoid contents, and its relation with the antioxidant and antifungal activity of methanolic extracts of Phellinus gilvus, Phellinus rimosus and Phellinus badius, ... | 2011 | 22100531 |
| process development for the elucidation of mycotoxin formation in alternaria alternata. | abstract: the black mould alternaria alternata produces a wide diversity of mycotoxins which are of particular health concern. since no maximum allowable limits are set for alternaria toxins in food and feed, prevention of alternaria infestations and mycotoxin spoilage is the only way to avoid health risks. thus, the understanding of mycotoxin biosynthesis is essential. for that purpose, a reliable batch process in a 2 l bioreactor was established which enables the study of several parameters in ... | 2011 | 21970547 |
| il-33-responsive lineage-cd25+cd44hi lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. | innate immunity provides the first line of response to invading pathogens and a variety of environmental insults. recent studies identified novel subsets of innate lymphoid cells that are capable of mediating immune responses in mucosal organs. in this paper, we describe a subset of lymphoid cells that is involved in innate type 2 immunity in the lungs. airway exposure of naive balb/c or c57bl/6j mice to il-33 results in a rapid (<12 h) production of il-5 and il-13 and marked airway eosinophilia ... | 2011 | 22198948 |
| non-dermatophyte moulds as pathogens of onychomycosis. | to determine the role and pattern of non-dermatophyte moulds as causative agents of onychomycosis. | 2011 | 22015119 |
| the involvement of jasmonates and ethylene in alternaria alternata f. sp. lycopersici toxin-induced tomato cell death. | previous studies have shown that an ethylene (et)-dependent pathway is involved in the cell death signalling triggered by alternaria alternata f. sp. lycopersici (aal) toxin in detached tomato (solanum lycopersicum) leaves. in this study, the role of jasmonic acid (ja) signalling in programmed cell death (pcd) induced by aal toxin was analysed using a 35s::prosystemin transgenic line (35s::prosys), a ja-deficient mutant spr2, and a ja-insensitive mutant jai1. the results indicated that ja biosyn ... | 2011 | 21865178 |
| increased chitinase expression and fungal-specific antibodies in the bronchoalveolar lavage fluid of asthmatic children. | background: increasing evidence highlights the contribution of chitinases and fungal infection to the development of asthma. objective: the purpose of this study was to characterize chitinase expression and serological markers of fungal infection in children with severe asthma. methods: bronchoalveolar lavage fluid (balf) was collected from children undergoing clinically indicated flexible bronchoscopy. a diagnosis of asthma was confirmed by pulmonary function testing. balf was tested for chitin ... | 2011 | 22092749 |
| two antifungal active triterpenoid saponins from the seeds of lathyrus plants. | two novel triterpenoid glycosides have been isolated from butanolic seeds extract of two varieties of lathyrus plants, i.e. lathyrus ratan and lathyrus aphaca. their structures were elucidated as 3-o-[β-d-glucuronopyranosyl-(1 → 4)-α-l-arabinopyranosyl-(1 → 2)-α-l-arabinopyranosyl]-olean-11,13(18)-dien-28-oic acid (1) and 3-o-{β-d-xylopyranosyl-(1 → 2)-β-d-glcopyranosyl-(1 → 4)-[β-d-glucopyranosyl-(1 → 2)]-β-d-xylopyranosyl}-2,16α-dihydroxy-4-hydroxymethyl urs-12-en-28-oic acid (2) on the basi ... | 2011 | 21899482 |
| Comment on the paper by Kpodzo et al. | | 2012 | 22114893 |
| dehydroaltenusin is a specific inhibitor of mammalian dna polymerase α. | introduction: we carried out a screen for small molecule selective inhibitors of eukaryotic dna polymerases (pols). dehydroaltenusin, isolated from a fungus (alternaria tenuis), was found to be a specific inhibitor of pol α. areas covered: we succeeded in chemically synthesizing dehydroaltenusin along with five analogs. of these compounds, dehydroaltenusin was the strongest and most specific inhibitor of mammalian pol α, with an ic(50) value of 0.68 μm. the inhibitory mode of action of dehydroal ... | 2011 | 21923630 |
| environmental factors and interactions with mycobiota of grain and grapes: effects on growth, deoxynivalenol and ochratoxin production by fusarium culmorum and aspergillus carbonarius. | mycotoxigenic fungi colonizing food matrices are inevitably competing with a wide range of other resident fungi. the outcomes of these interactions are influenced by the prevailing environmental conditions and the competing species. we have evaluated the competitiveness of f. culmorum and a. carbonarius in the grain and grape food chain for their in vitro and in situ dominance in the presence of other fungi, and the effect that such interactions have on colony interactions, growth and deoxynival ... | 2010 | 22069589 |
| association between indoor fungi in delhi homes and sensitization in children with respiratory allergy. | indoor fungi are potential sensitizing agents in children and their detection and quantification in indoor air are important in the diagnosis and environmental management of fungal allergies. the objective of this investigation was to assess the prevalence of fungal allergies in children in delhi and to study the association between mold counts in the homes of children and their sensitization to respective fungal extracts. fungal concentrations and seasonality were studied at two-week intervals ... | 2011 | 22103346 |
| isolation and identification of microbes associated with mobile phones in dammam in eastern saudi arabia. | this study was conducted to determine microbial contamination of mobile phones in the city of dammam, in the eastern region of saudi arabia, and identify the most important microbial species associated with these phones in order to take the necessary remedial measures. | 2010 | 22022665 |
| Antifungal susceptibility profile of clinical Alternaria spp. identified by molecular methods. | To analyse the susceptibility pattern of a collection of Alternaria spp. clinical isolates. | 2011 | 21921077 |
| respiratory allergy to fungi in barcelona, spain: clinical aspects, diagnosis and specific treatment in a general allergy unit. | background: the importance of hypersensitivity to fungal allergens is a relatively unknown and somewhat controversial subject. methods: an open prospective study was carried out in just one centre to determine the clinical and epidemiological characteristics as well as the diagnostic usefulness of skin prick and conjunctiva provocation tests, associated with total and specific ige determination in two groups of patients, one of which was monosensitised to fungi and the other of which had multipl ... | 2011 | 22136809 |
| Screening of allelopathic trees for their antifungal potential against Alternaria alternata strains isolated from dying-back Eucalyptus spp. | Antifungal activity of methanolic extracts of leaves of three tree species, namely Azadirachta indica L., Syzygium cumini (L.) Skeels. and Melia azedarach L. was evaluated against two strains of Alternaria alternata, isolated from dying-back trees of two Eucalyptus spp., namely Eucalyptus citriodora and Eucalyptus globulus. All the concentrations (1,?2,?…?,?5% w/v) of the methanolic extracts of the three tree species significantly reduced the fungal biomass. There were reductions in the ranges 8 ... | 2011 | 22007991 |
| Clinical significance of Alternaria alternata sensitization in patients with allergic rhinitis. | PURPOSE: The aim of the study was to determine the epidemiologic profile of Alternaria alternata (AA)-sensitized patients with allergic rhinitis including coexistence of other atopic diseases, seasonal distribution of AA aeroallergens, age of onset of AA sensitization, and prevalence of sensitization to other allergens. MATERIALS AND METHODS: History, clinical examination, and skin prick tests were performed in 623 patients with allergic rhinitis from central Greece. Patients' age, cosensitizati ... | 2011 | 21907454 |
| Airway responsiveness in an allergic rabbit model. | Animal models of allergy and bronchial hyperresponsiveness (BHR) are useful in researching pulmonary diseases and evaluating drug effects on the airways. Neonatally immunised rabbits exhibit several features of asthma as adults, including early and late airway responses following antigen challenge, oedema and inflammatory cell infiltration into the lung, BHR to inhaled histamine and methacholine (compared with naïve rabbits) and exacerbations of BHR following antigen challenge. Therefore this mo ... | 2011 | 21854860 |
| in vitro antifungal activity of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol against mycotoxigenic plant pathogens. | the aim of this study was to examine the effect of five naturally occurring compounds from essential oils on 10 different species of mycotoxigenic fungi involved in several plant diseases. the antifungal activities of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol were observed in vitro on fusarium subglutinans, fusarium cerealis, fusarium verticillioides, fusarium proliferatum, fusarium oxysporum, fusarium sporotrichioides, aspergillus tubingensis, aspergillus carbonarius, ... | 2011 | 22257275 |
| the effect of seed-borne mycoflora from sorghum and foxtail millet seeds on germination and disease transmission. | the seed-borne mycoflora of sorghum and foxtail millet collected from different growing areas in south korea were isolated and taxonomically identified using dry inspection, standard blotter and the agar plate method. we investigated the in vitro and in vivo germination rates of disinfected and non-disinfected seeds of sorghum and foxtail millet using sterilized and unsterilized soil. the percent recovery of seed-borne mycoflora from the seed components of sorghum and foxtail millet seeds was de ... | 2011 | 22783105 |
| biocontrol potential of siderophore producing heavy metal resistant alcaligenes sp. and pseudomonas aeruginosa rzs3 vis-à-vis organophosphorus fungicide. | in present study in vitro phytopathogen suppression activity of siderophoregenic preparations of ni and mn resistant alcaligenes sp. stc1 and pseudomonas aeruginosa rzs3 sh-94b isolated from soil were found superior over the chemical pesticide. siderophore rich culture broth and siderophore rich supernatant exerted antifungal activity against aspergillus niger ncim 1025, aspergillus flavus ncim 650, fusarium oxysporum ncim 1281, alternaria alternata ari 715, cercospora arachichola, metarhizium a ... | 2011 | 22754001 |
| [prevalence of sensitization to aeroallergens in 10 030 patients with allergic rhinitis]. | to investigate the main inhaled allergens in patients with allergic rhinitis. | 2011 | 22335978 |
| antifungal activity and isomerization of octadecyl p-coumarates from ipomoea carnea subsp. fistulosa. | bioassay monitored hplc assisted isolation and purification of the chief antifungal fraction of the leaves of ipomoea carnea subsp. fistulosa (convulvulaceae) were achieved using colletotrichum gloeosporioides and cladosporium cucumerinum as test organisms. the activity of the purified fraction was further confirmed by the dose dependent inhibition of the spore germination of alternaria alternata and a. porri. the active fraction was identified as a mixture of (e)-octadecyl p-coumarate and (z)-o ... | 2011 | 22312731 |
| a sheep model to investigate the role of fungal biofilms in sinusitis: fungal and bacterial synergy. | the role of fungi in the spectrum of chronic rhinosinusitis (crs) is poorly understood. fungal biofilms have recently been discovered in crs patients. we have developed an animal model for the investigation of sinonasal fungal biofilms. the role of type i hypersensitivity and pathogenic bacteria is presented. | 2011 | 22287463 |
| assessing the mycotoxigenic threat of necrotrophic pathogens of wheat. | pathogenic fungi are the causal agents of many significant plant diseases around the world. these diseases often result in significant yield reductions, leading to lower food production rates and economic losses. several of these pathogenic fungi also produce mycotoxins during infection, which are harmful to human and animal health. whilst some of these toxins and the fungi that produce them have been studied intensively, the mycotoxigenic potential of many of these pathogens remains largely unk ... | 2011 | 23605924 |
| currency notes and coins as a possible source of transmitting fungal pathogens of man and plants. | currency (notes and coins) handling by people during transaction is one of the most mobile objects within the community, which has a potential of transmitting pathogens. a survey carried out recently in nanded city (maharashtra) revealed heavy contamination of currency notes and coins by important fungal pathogens of plants and man, i.e. aspergillus niger (60.37%), a. flavus (3.98%), a.nidulans (0.2%), penicillium citrinum (17.80%), alternaria tenuis (0.20%), curvularia pallescens (0.20%), clado ... | 2011 | 23505834 |
| in vitro susceptibility of filamentous fungi to copper nanoparticles assessed by rapid xtt colorimetry and agar dilution method. | metal nanoparticles and their uses in various aspects have recently drawn a great deal of attention. one of the major applications is that it can be used as an antimicrobial agent. they can be considered in approaches targeted to decrease the harms caused by microorganisms, specifically fungi, threatening the medical and industrial areas. the aim of this study was to investigate the antifungal activity of synthesized copper nanoparticles (cunps) against four filamentous fungi including alternari ... | 2012 | 23518166 |
| pentraxin 3 in children suffering from allergic rhinitis. | allergic disorders are typically characterized by an inflammatory response to allergen exposure. ptx3 behaves as an acute-phase response protein as there is a relationship between ptx3 plasma levels and disease severity. therefore, this study was designed to investigate a possible role of ptx3 in children with allergic rhinitis. one hundred patients (28 females, 72 males, median age 11 years) were enrolled in the study. all patients were monosensitized: 43 (43%) to seasonal allergens (graminacea ... | 2012 | 22691257 |
| the application of bioactive compounds from the food industry to control mold growth in indoor waterborne coatings. | microbial growth in indoor environments creates health problems, especially in people with asthma; approximately 80% of these patients are allergic to mold. antimicrobial coatings are formulated to generate surfaces that are easy to clean and may also incorporate active agents, commonly called biocides, which inhibit microbial colonization, subsequent growth and bio-deterioration of the substrates. some research lines seek to replace traditional organometallic and organochlorines biocides with e ... | 2012 | 23298599 |
| prevalence and associated risk factors of allergic rhinitis in preschool children in beijing. | to investigate the prevalence of allergic rhinitis (ar) and its associated risk factors in preschool children in beijing. | 2012 | 23280940 |
| appressorium-localized nadph oxidase b is essential for aggressiveness and pathogenicity in the host-specific, toxin-producing fungus alternaria alternata japanese pear pathotype. | black spot disease, alternaria alternata japanese pear pathotype, produces the host-specific toxin ak-toxin, an important pathogenicity factor. previously, we have found that hydrogen peroxide is produced in the hyphal cell wall at the plant-pathogen interaction site, suggesting that the fungal reactive oxygen species (ros) generation machinery is important for pathogenicity. in this study, we identified two nadph oxidase (noxa and noxb) genes and produced nox disruption mutants. δnoxa and δnoxb ... | 2012 | 23279187 |
| in vitro and in vivo biocontrol of soil-borne phytopathogenic fungi by certain bioagents and their possible mode of action. | the study aimed to investigate new wide-spectrum biological control agents against soil-borne fungal plant pathogens. screening of 336 fungal strains and 256 bacterial strains was carried out in vitro to select the most promising isolates for controlling destructive pathogens of greenhouse-vegetables. in dual cultures, bacillus subtilis jf419701 and trichoderma harzianum jf419706 (teleomorph: hypocrea lixii) inhibited the growth of alternaria alternata, fusarium oxysporum, exserohilum rostratum, ... | 2012 | 23269217 |
| supramolecular coordination and antimicrobial activities of constructed mixed ligand complexes. | a novel series of copper(ii) and palladium(ii) with 4-derivatives benzaldehyde pyrazolone (l(n)) were synthesized. the mixed ligand complexes were prepared by using 1,10-phenanthroline (phen) as second ligand. the structure of these complexes was identified and confirm by elemental analysis, molar conductivity, uv-vis, ir and (1)h nmr spectroscopy and magnetic moment measurements as well as thermal analysis. the ligand behaves as a neutral bidentate ligand through on donor sites. esr spectra sho ... | 2012 | 23268204 |
| [the chemiluminescent detection of activity in peripheral blood neutrophils under allergic diseases of lungs in children with fungous sensibilization]. | the high mobilization activity of neutrophils as a capacity of momentary feed-back reaction to factually any external stimuli, make it possible to use them in various diagnostic systems in vitro. among them is the automated test system of chemiluminescent detection of functional activity of peripheral blood neutrophils in parallel response to luminol, opsonizing zymosan and different antigens. this approach makes it possible to evaluate the initial and induced activity of phagocytes and its dyna ... | 2012 | 23265057 |
| isolation and characterization of the grain mold fungi cochliobolus and alternaria spp. from sorghum using semiselective media and dna sequence analyses. | mold diseases, caused by fungal complexes including alternaria, cochliobolus, and fusarium species, limit sorghum grain production. media were tested by plating fusarium thapsinum, alternaria sp., and curvularia lunata, individually and competitively. dichloran chloramphenicol rose bengal (drbc) and modified v8 juice (modv8) agars, found to be useful, were compared with commonly used agar media, dichloran chloramphenicol peptone (dcpa) and pentachloronitrobenzene (pcnb). radial growth, starting ... | 2012 | 23461515 |
| plant growth promotion activity of keratinolytic fungi growing on a recalcitrant waste known as "hair waste". | purpureocillium lilacinum (thom) samsom is one of the most studied fungi in the control of plant parasitic nematodes. however, there is not specific information on its ability to inhibit some pathogenic bacteria, fungi, or yeast. this work reports the production of several antifungal hydrolytic enzymes by a strain of p. lilacinum when it is grown in a medium containing hair waste. the growth of several plant-pathogenic fungi, alternaria alternata, aspergillus niger, and fusarium culmorum, was co ... | 2015 | 26697226 |
| molecular mechanisms underlying the close association between soil burkholderia and fungi. | bacterial species belonging to the genus burkholderia have been repeatedly reported to be associated with fungi but the extent and specificity of these associations in soils remain undetermined. to assess whether associations between burkholderia and fungi are widespread in soils, we performed a co-occurrence analysis in an intercontinental soil sample collection. this revealed that burkholderia significantly co-occurred with a wide range of fungi. to analyse the molecular basis of the interacti ... | 2015 | 25989372 |
| a survey of the quantity and type of biological aerosols in selected wards of a teaching hospital in ghazvin. | bioaerosols are agents that can cause infection, allergy or induce other toxic effects in the human body. if the person exposed to such particles is not capable of their destruction or elimination from the body, the established chemical and physiological disorders can result in disease or death. the aim of this study was to assess the concentrations of bioaerosols in several wards of a teaching hospital. | 2016 | 27280005 |
| a highly-conserved single-stranded dna-binding protein in xanthomonas functions as a harpin-like protein to trigger plant immunity. | harpins are produced by gram-negative phytopathogenic bacteria and typically elicit hypersensitive response (hr) in non-host plants. the characterization of harpins in xanthomonas species is largely unexplored. here we demonstrate that xanthomonas produce a highly conserved single-stranded dna-binding protein (ssb(x)) that elicits hr in tobacco as by harpin hpa1. ssb(x), like hpa1, is an acidic, glycine-rich, heat-stable protein that lacks cysteine residues. ssb(x)-triggered hr in tobacco, as by ... | 2013 | 23418541 |
| effect of crude plant extracts from some oaxacan flora on two deleterious fungal phytopathogens and extract compatibility with a biofertilizer strain. | the antimicrobial activity of 12 plant extracts was tested against the phytopathogens alternaria alternata and fusarium solani. in addition, the compatibility of the extracts toward bacillus liqueniformis, a biofertilizer and a non-target microorganism, was assessed. plants tested belong to the euphorbiaceae, asteraceae, crassulaceae, rubiaceae, convolvulaceae, verbenaceae, orchidaceae, nyctaginaceae, boraginaceae, and tiliaceae families and were collected in the state of oaxaca. the antifungal ... | 2014 | 25147544 |
| multiple phytohormone signalling pathways modulate susceptibility of tomato plants to alternaria alternata f. sp. lycopersici. | three phytohormone molecules - ethylene (et), jasmonic acid (ja) and salicylic acid (sa) - play key roles in mediating disease response to necrotrophic fungal pathogens. this study investigated the roles of the et, ja, and sa pathways as well as their crosstalk during the interaction between tomato (solanum lycopersicum) plants and a necrotrophic fungal pathogen alternaria alternata f. sp. lycopersici (aal). both the et and jasmonic acid insensitive1 (jai1) receptor-dependent ja signalling pathw ... | 2013 | 23264518 |
| scopoletin is a phytoalexin against alternaria alternata in wild tobacco dependent on jasmonate signalling. | alternaria alternata (tobacco pathotype) is a necrotrophic fungus causing severe losses in nicotiana species by infection of mature leaves. similar to what has been observed in cultivated tobacco, n. tabacum, young leaves of wild tobacco, n. attenuata, were more resistant to a. alternata than mature leaves, and this was correlated with stronger blue fluorescence induced after infection. however, the nature of the fluorescence-emitting compound, its role in defence, and its regulation were not cl ... | 2014 | 24821958 |
| a pathogenesis related protein, vppr-10.1, from vitis pseudoreticulata: an insight of its mode of antifungal activity. | previously, vppr-10.1 was isolated and characterized from a cdna library of a fungus-resistant accession of chinese wild grape (vitis pseudoreticulata). we found that expression of vppr-10.1 is affected by the fungal pathogen erysiphe necator. to investigate the biochemical basis of the nuclease activity of vppr-10.1 and its role in antifungal resistance, we generated recombinant vppr-10.1 as well as site-directed mutations targeting three conserved amino acid residues among plant pr-10 s: lys55 ... | 2014 | 24759805 |
| candidate resistant genes of sand pear (pyrus pyrifolia nakai) to alternaria alternata revealed by transcriptome sequencing. | pear black spot (pbs) disease, which is caused by alternaria alternata (aa), is one of the most serious diseases affecting sand pear (pyrus pyrifolia nakai) cultivation worldwide. to investigate the defense mechanisms of sand pear in response to aa, the transcriptome of a sand pear germplasm with differential resistance to aa was analyzed using illumina paired-end sequencing. four libraries derived from pbs-resistant and pbs-susceptible sand pear leaves were characterized through inoculation or ... | 2015 | 26292286 |
| hyperspectral and thermal imaging of oilseed rape (brassica napus) response to fungal species of the genus alternaria. | in this paper, thermal (8-13 µm) and hyperspectral imaging in visible and near infrared (vnir) and short wavelength infrared (swir) ranges were used to elaborate a method of early detection of biotic stresses caused by fungal species belonging to the genus alternaria that were host (alternaria alternata, alternaria brassicae, and alternaria brassicicola) and non-host (alternaria dauci) pathogens to oilseed rape (brassica napus l.). the measurements of disease severity for chosen dates after inoc ... | 2015 | 25826369 |
| priming by hexanoic acid induce activation of mevalonic and linolenic pathways and promotes the emission of plant volatiles. | hexanoic acid (hx) is a short natural monocarboxylic acid present in some fruits and plants. previous studies reported that soil drench application of this acid induces effective resistance in tomato plants against botrytis cinerea and pseudomonas syringae and in citrus against alternaria alternata and xanthomonas citri. in this work, we performed an in deep study of the metabolic changes produced in citrus by the application of hx in response to the challenge pathogen a. alternata, focusing on ... | 2016 | 27148319 |
| effects of essential oils from eucalyptus globulus leaves on soil organisms involved in leaf degradation. | the replacement of native portuguese forests by eucalyptus globulus is often associated with deleterious effects on terrestrial and aquatic communities. several studies have suggested that such a phenomenon is linked with the leaf essential oils released into the environment during the eucalyptus leaf degradation process. however, to date, the way these compounds affect leaf degradation in terrestrial systems i.e. by direct toxic effects to soil invertebrates or indirectly by affecting food of s ... | 2013 | 23577212 |
| phytochemical and antimicrobial studies of methyl angolensate and luteolin-7-o-glucoside isolated from callus cultures of soymida febrifuga. | soymida febrifuga (roxb.) a. juss. is an indigenous lofty deciduous medicinal tree, monotypic genus endemic to india. hexane, ethyl acetate and methanol extracts of soymida febrifuga root callus were tested for their phytochemical constituents and antimicrobial activity. among them, ethyl acetate extract was found to be most effective, which on subjection to silica gel column chromatography led to the separation and isolation of methyl angolensate and luteolin-7-o-glucoside. structures were dete ... | 2007 | 23675053 |
| microbial diversity and dynamics during the production of may bryndza cheese. | diversity and dynamics of microbial cultures were studied during the production of may bryndza cheese, a traditional slovak cheese produced from unpasteurized ewes' milk. quantitative culture-based data were obtained for lactobacilli, lactococci, total mesophilic aerobic counts, coliforms, e. coli, staphylococci, coagulase-positive staphylococci, yeasts, fungi and geotrichum spp. in ewes' milk, curd produced from it and ripened for 0 - 10 days, and in bryndza cheese produced from the curd, in th ... | 2014 | 24291178 |
| molecular characterization of microbial communities in bioaerosols of a coal mine by 454 pyrosequencing and real-time pcr. | microbial diversity and abundance in bioaerosols of a coal mine were analyzed based on 454 pyrosequencing and real-time polymerase chain reaction (pcr). a total of 37,191 high quality sequences were obtained and could be classified into 531, 1730 and 448 operational taxonomic units respectively for archaea, bacteria and fungi at 97% sequence similarity. the shannon diversity index for archaea, bacteria and fungi was respectively 4.71, 6.29 and 3.86, indicating a high diversity in coal mine bioae ... | 2015 | 25872733 |
| production of taxadiene by engineering of mevalonate pathway in escherichia coli and endophytic fungus alternaria alternata tpf6. | taxol (paclitaxel) is a diterpenoid compound with significant and extensive applications in the treatment of cancer. the production of taxol and relevant intermediates by engineered microbes is an attractive alternative to the semichemical synthesis of taxol. in this study, based on a previously developed platform, the authors first established taxadiene production in mutant e. coli t2 and t4 by engineering of the mevalonate (mva) pathway. the authors then developed an agrobacterium tumefaciens- ... | 2017 | 28217906 |
| synthesis and structure-activity relationship of n-(cinnamyl) chitosan analogs as antimicrobial agents. | the current study focuses on the preparation of new n-(cinnamyl) chitosan derivatives as antimicrobial agents against nine types of crop-threatening pathogens. chitosan was reacted with a set of aromatic cinnamaldehyde analogs by reductive amination involving formation of the corresponding imines, followed by reduction with sodium borohydride to produce n-(cinnamyl) chitosan derivatives. the structural characterization was confirmed by (1)h and (13)c nmr spectroscopy and the degrees of substitut ... | 2013 | 23511055 |
| cloning and functional analysis of a novel chitinase gene trchi1 from trichothecium roseum. | chitinases produced by mycoparasites play an important role in disease control in plants. to explore the functions of chitinases in trichothecium roseum, we cloned a new chitinase gene named trchi1 from t. roseum by rt (reverse transcription)-pcr techniques. the t. roseum gene, trchi1, contains an 1278-bp orf that shares 76 % similarity with chitinase from bionectria ochroleuca (abv57861 3g6l_a). a plant expression vector, containing the trchi1 gene driven by the camv35s promoter, was constructe ... | 2012 | 22760177 |
| β2 integrins rather than β1 integrins mediate alternaria-induced ilc2 trafficking to the lung. | group 2 innate lymphoid cells (ilc2s) expand in the lungs of mice during type 2 inflammation induced by the fungal allergen alternaria alternata. the increase in ilc2 numbers in the lung has been largely attributed to local proliferation and whether ilc2s migrate from the circulation to the lung following alternaria exposure is unknown. | 2017 | 28366795 |
| tea is a key virulence factor for alternaria alternata (fr.) keissler infection of its host. | a toxin-deficient mutant strain, hp001 mutant of alternaria alternata, whose mycelium is unable to infect its host, produces little tenuazonic acid (tea) toxin. how tea plays a role in initiating host infection by a. alternata remains unclear. in this research we use imaging-pam based on chlorophyll fluorescence parameters and transmission electron microscopy to explore the role of tea toxin during the infection process of a. alternata. photosystem ii damage began even before wild type mycelium ... | 2017 | 28324684 |
| evaluation of phenolic compounds and antioxidant and antimicrobial activities of some common herbs. | the study was designed to evaluate the phenolic, flavonoid contents and antioxidant and antimicrobial activities of onion (allium cepa), garlic (allium sativum), mint (mentha spicata), thyme (thymus vulgaris), oak (quercus), aloe vera (aloe barbadensis miller), and ginger (zingiber officinale). all extracts showed a wide range of total phenolic contents, that is, 4.96 to 98.37 mg/100 g gallic acid equivalents, and total flavonoid contents, that is, 0.41 to 17.64 mg/100 g catechin equivalents. an ... | 2017 | 28316626 |
| plasma-based degradation of mycotoxins produced by fusarium, aspergillus and alternaria species. | the efficacy of cold atmospheric pressure plasma (capp) with ambient air as working gas for the degradation of selected mycotoxins was studied. deoxynivalenol, zearalenone, enniatins, fumonisin b1, and t2 toxin produced by fusarium spp., sterigmatocystin produced by aspergillus spp. and aal toxin produced by alternaria alternata were used. the kinetics of the decay of mycotoxins exposed to plasma discharge was monitored. all pure mycotoxins exposed to capp were degraded almost completely within ... | 2017 | 28287436 |
| establishment of crispr/cas9 in alternaria alternata. | the filamentous fungus alternaria alternata is a potent producer of many secondary metabolites, some of which like alternariol or alternariol-methyl ether are toxic and/or cancerogenic. many alternaria species do not only cause post-harvest losses of food and feed, but are aggressive plant pathogens. despite the great economic importance and the large number of research groups working with the fungus, the molecular toolbox is rather underdeveloped. gene deletions often result in heterokaryotic s ... | 2017 | 28286319 |
| comparative transcriptomic analysis reveals that ethylene/h2o2-mediated hypersensitive response and programmed cell death determine the compatible interaction of sand pear and alternaria alternata. | a major restriction on sand pear (pyrus pyrifolia) production is black spot disease caused by the necrotrophic fungus alternaria alternata. however, the pear response mechanism to a. alternata is unknown at the molecular level. here, host responses of a resistant cultivar cuiguan (cg) and a susceptible cultivar sucui1 (sc1) to a. alternata infection were investigated. we found that the primary necrotic lesion formed at 1 dpi and the expansion of lesions was aggressive in sc1. data from transcrip ... | 2017 | 28261248 |
| enzyme inhibitory metabolites from endophytic penicillium citrinum isolated from boswellia sacra. | fungal endophytes establish an important niche within the host plant through the secretion of chemical constituents. isolation of bioactive metabolites could be a vital source for inhibiting the function of enzymes such as α-glucosidase and urease. the present study aimed to elucidate the potential of endophytes associated with boswellia sacra through bioassay-guided isolation and identification of secondary metabolites with enzyme inhibitory ability. endophytic fungal strains viz. penicillium c ... | 2017 | 28220202 |
| identification of a novel alternaria alternata strain able to hyperparasitize puccinia striiformis f. sp. tritici, the causal agent of wheat stripe rust. | the obligate bitrophic fungus puccinia striiformis f. sp. tritici (pst) causes stripe (yellow) rust on wheat worldwide. here, we report a novel fungal strain able to hyperparasitize pst. the strain was isolated from gray-colored rust pustules, and was identified as alternaria alternata (fr.: fr.) keissler based on a combination of morphological characteristics and multi-locus (its, gapdh, and rpb2) phylogeny. upon artificial inoculation, the hyperparasite reduced the production and viability of ... | 2017 | 28197134 |
| antimicrobial activity of endophytic fungi from olive tree leaves. | in this study, the antimicrobial potential of three fungal endophytes from leaves of olea europaea l. was evaluated and the host plant extract effect in the antimicrobial activity was examined. the volatile compounds produced by endophytes were identified by gc/ms and further correlated with the antimicrobial activity. in potato dextrose agar, both penicillium commune and penicillium canescens were the most effective inhibiting gram-positive and -negative bacteria (up to 2.7-fold compared to 30 ... | 2017 | 28168624 |
| morphogenetic alterations of alternaria alternata exposed to dicarboximide fungicide, iprodione. | fungicide-resistant alternaria alternata impede the practical control of the alternaria diseases in crop fields. this study aimed to investigate cytological fungicide resistance mechanisms of a. alternata against dicarboximide fungicide iprodione. a. alternata isolated from cactus brown spot was cultured on potato-dextrose agar (pda) with or without iprodione, and the fungal cultures with different growth characteristics from no, initial and full growth were observed by light and electron micros ... | 2017 | 28167893 |
| transcriptomics analysis of apple leaves in response to alternaria alternata apple pathotype infection. | alternaria blotch disease of apple (malus × domestica borkh.), caused by the apple pathotype of alternaria alternata, is one of the most serious fungal diseases to affect apples. to develop an understanding of how apples respond to a. alternata apple pathotype (aaap) infection, we examined the host transcript accumulation over the period between 0 and 72 h post aaap inoculation. large-scale gene expression analysis was conducted of the compatible interaction between "starking delicious" apple cu ... | 2017 | 28163714 |
| microbial rrna sequencing analysis of evaporative cooler indoor environments located in the great basin desert region of the united states. | recent studies conducted in the great basin desert region of the united states have shown that skin test reactivity to fungal and dust mite allergens are increased in children with asthma or allergy living in homes with evaporative coolers (ec). the objective of this study was to determine if the increased humidity previously reported in ec homes leads to varying microbial populations compared to homes with air conditioners (ac). children with physician-diagnosed allergic rhinitis living in ec o ... | 2017 | 28091681 |
| identification of a. arborescens, a. grandis, and a. protenta as new members of the european alternaria population on potato. | alternaria species, primarily the small-spored alternaria alternata and the large-spored alternaria solani, are considered a serious threat to potato cultivation. to develop control strategies, it is important to gain insight into the alternaria population. based on the sequence analyses of the internal transcribed spacer region (its) and the glyceraldehyde-3-phosphate dehydrogenase gene, the small-spored and large-spored alternaria isolates could be separated from each other. sequence analyses ... | 2017 | 28089048 |
| fine mapping for identification of citrus alternaria brown spot candidate resistance genes and development of new snp markers for marker-assisted selection. | alternaria brown spot (abs) is a serious disease affecting susceptible citrus genotypes, which is a strong concern regarding citrus breeding programs. resistance is conferred by a recessive locus (absr) previously located by our group within a 3.3 mb genome region near the centromere in chromosome iii. this work addresses fine-linkage mapping of this region for identifying candidate resistance genes and develops new molecular markers for abs-resistance effective marker-assisted selection (mas). ... | 2016 | 28066498 |
| a major facilitator superfamily transporter-mediated resistance to oxidative stress and fungicides requires yap1, skn7, and map kinases in the citrus fungal pathogen alternaria alternata. | major facilitator superfamily (mfs) transporters play an important role in multidrug resistance in fungi. we report an aamfs19 gene encoding a mfs transporter required for cellular resistance to oxidative stress and fungicides in the phytopathogenic fungus alternaria alternata. aamfs19, containing 12 transmembrane domains, displays activity toward a broad range of substrates. fungal mutants lacking aamfs19 display profound hypersensitivities to cumyl hydroperoxide, potassium superoxide, many sin ... | 2017 | 28060864 |
| clinical relevance of ige-mediated sensitization against the mould alternaria alternata in children with asthma. | asthma in childhood has a prevalence of 5-10% in germany and severe asthma accounts for about 5% in this patient group. positive predictive values for severe asthma are atopy, a positive family history and sensitizations against inhalative allergens. alternaria is an important inhalative allergen and sensitization is suspected to correlate with severe and lethal asthma. we investigated the prevalence and impact of alternaria sensitization in paediatric asthma. | 2017 | 28043213 |
| characterization of microbial population of breba and main crops (ficus carica) during cold storage: influence of passive modified atmospheres (map) and antimicrobial extract application. | the purpose of this work was to study the changes of bacterial and fungal population of breba fruits such as 'banane' and 'san antonio' as well as 'cuello dama negro', 'cuello dama blanco' and 'san antonio' fig cultivars stored in passive modified atmospheres (map) by the use of three different microperforated films (m10 with 16 holes; m30 with five holes and m50 with three holes). moreover the effects of the application of aqueous soy polyphenolic antimicrobial extract (ape), alone or combined ... | 2017 | 28040180 |
| enzymatic activity of fungi isolated from crops. | to detect and assess the activity of extracellular hydrolytic enzymes and to find differences in enzymograms between fungi isolated from wheat and rye samples and grown on czapek-dox broth and sabouraud dextrose broth enriched with cereal (wheat or rye). isolated strains were also classified in the scale of biosafety levels (bsl). | 2016 | 28035224 |
| sandpits as a reservoir of potentially pathogenic fungi for children. | fungi belonging to various physiological and morphological groups present in the environment are potential human pathogens. some of them are considered as emerging pathogens. therefore, their presence in children's playgrounds should be regarded as health risk factor. | 2016 | 28030920 |
| sphingolipids, ormdl3 and asthma: what is the evidence? | genome-wide association studies identified ormdl3, a protein of the endoplasmic reticulum, as a significant asthma risk factor. ormdl3 is one of three ormdl proteins that integrate multiple signals to maintain sphingolipid homeostasis. studies that investigated potential mechanisms for how increased ormdl3 might affect asthma are summarized. | 2017 | 28030368 |
| in vitro combinatory effects of the alternaria mycotoxins alternariol and altertoxin ii and potentially involved mirnas. | alternariol (aoh) and altertoxin ii (atx ii) are mycotoxins formed by alternaria spp. since they are expected to co-occur in alternaria-infested food and feed, we addressed the question of combinatory effects. in addition, potentially involved regulatory micrornas were surveyed in an exploratory approach. cytotoxicity measurements in constant ratio combinations of 1:10 or 1:1 (atx ii: aoh) mainly revealed additive effects in hepg2, ht29 and hcec-1ct cells. yet, in specific high doses antagonism ... | 2017 | 28007639 |
| induced resistance in tomato fruit by γ-aminobutyric acid for the control of alternaria rot caused by alternaria alternata. | the study investigated the effect of γ-aminobutyric acid (gaba) on the control of alternaria rot in tomato fruit and the possible mechanism involved. our results showed exogenous gaba could stimulate remarkable resistance to the alternaria rot, while it had no direct antifungal activity against alternaria alternata. moreover, the activities of antioxidant enzymes, including peroxidase, superoxide dismutase and catalase, along with the expression of these corresponding genes, were significantly i ... | 2017 | 27979053 |
| composition of endophytic fungal community associated with leaves of maize cultivated in south brazilian field. | the objective of this study was to conduct a survey about fungi associated with leaves from two different maize plant lineages and to analyze their microbiota diversity. isolated fungi were identified by morphological analysis and molecular taxonomy was performed using its1-5.8s-its2 rdna. about 27 fungi morphotypes were obtained, 15 of them were from the first maize lineage. about 86.7% of the individuals belonged to the dothideomycetes class (phoma sorghina, epicocum nigrum, cladosporium sp., ... | 2016 | 27936873 |
| identification, characterization and phylogenetic analysis of antifungal trichoderma from tomato rhizosphere. | the use of trichoderma isolates with efficient antagonistic activity represents a potentially effective and alternative disease management strategy to replace health hazardous chemical control. in this context, twenty isolates were obtained from tomato rhizosphere and evaluated by their antagonistic activity against four fungal pathogens (fusarium oxysporum f. sp. lycopersici, alternaria alternata, colletotrichum gloeosporoides and rhizoctonia solani). the production of extracellular cell wall d ... | 2016 | 27917337 |
| desensitization of idiopathic pulmonary fibrosis fibroblasts to alternaria alternata extract-mediated necrotic cell death. | alternaria alternata is an allergenic fungus and known to cause an upper respiratory tract infection and asthma in humans with compromised immunity. although a. alternata's effect on airway epithelial cells has previously been examined, the potential role of a. alternata on lung fibroblast viability is not understood. since lung fibroblasts derived from patients with idiopathic pulmonary fibrosis (ipf) display a distinct phenotype that is resistant to stress and cell death inducing conditions, t ... | 2016 | 27905295 |
| fungal endophytic communities associated to the phyllosphere of grapevine cultivars under different types of management. | fungal endophytes present in different asymptomatic grapevine plants (vitis vinifera l.) located in different vineyards within alentejo, a highly important viticulture region in portugal, were identified in this study. sampled grapevine plants included the three most representative cultivars in the region, syrah, cabernet sauvignon, and aragonez, growing under two different modes of management, conventional and biological. sixteen fungal taxa were identified through sequencing of the internal tr ... | 2016 | 27890088 |
| development of a dot-blot assay for the detection of mould-specific ige in the belgian population. | data on mould sensitization in the general population are scarce and mostly on aspergillus fumigatus, alternaria alternata and cladosporium herbarum. | 2017 | 27878528 |
| near-fatal asthma: a heterogeneous clinical entity. | the aims of the present review were to describe the heterogeneous nature of near-fatal asthma (nfa) and to summarize the distinctive phenotypes identified in this subtype of asthma. | 2017 | 27870665 |
| water activity and temperature effects on growth and mycotoxin production by alternaria alternata strains isolated from malbec wine grapes. | to study the effects of water activity (aw ; 0·99, 0·98, 0·97, 0·96 and 0·95), temperature (15, 25 and 30°c), incubation time (7-28 days), and their interactions on mycelial growth and alternariol (aoh), alternariol monomethyl ether (ame) and tenuazonic acid (ta) mycotoxin production on a synthetic nutrient (sn) media similar to grape composition by three strains of alternaria alternata isolated from wine grapes from argentina. | 2017 | 27860113 |
| development and validation of a lc-esi-ms/ms method for the determination of alternaria toxins alternariol, alternariol methyl-ether and tentoxin in tomato and tomato-based products. | alternaria species are capable of producing several secondary toxic metabolites in infected plants and in agricultural commodities, which play important roles in food safety. alternaria alternata turn out to be the most frequent fungal species invading tomatoes. alternariol (aoh), alternariol monomethyl ether (ame), and tentoxin (ten) are some of the main alternaria mycotoxins that can be found as contaminants in food. in this work, an analytical method based on liquid chromatography (lc) tandem ... | 2016 | 27845716 |
| an eco-friendly route of γ-fe2o3 nanoparticles formation and investigation of the mechanical properties of the hpmc-γ-fe2o3 nanocomposites. | in recent times, biosynthetic approaches toward the synthesis of nanoparticles have been shown to have several advantages over physical and chemical methods. here, we report the extracellular mycosynthesis of γ-fe2o3 nanoparticles by alternaria alternata. the fungal biomass when exposed to aqueous iron(iii) chloride solution led to the formation of highly stable γ-fe2o3 nanoparticles extracellularly. the influence of these biosynthesized γ-fe2o3 nanoparticles on the properties of hydroxyl propyl ... | 2017 | 27826743 |
| alternaria alternata acts on human monocyte-derived dendritic cells to mediate th2/th17 polarisation. | although the mechanism of asthma is not precisely understood in humans, clinical and epidemiological studies have offered a potential relationship between exposure to environmental fungi, such as alternaria alternata (a. alternata) and the development and exacerbation of asthma. the aim of this project is to investigate the mechanisms of th2 responses by a. alternata as a clinically relevant model for the environmental exposure. | 2017 | 27823917 |
| stat6 regulates the development of eosinophilic versus neutrophilic asthma in response to alternaria alternata. | human asthma is a heterogeneous disease characterized by the expression of both th2 and th17 cytokines. in vitro and in vivo studies have shown a reciprocal regulation between th2 and th17 pathways, suggesting a potential induction of neutrophil-promoting th17 inflammation in the absence of a th2 response. alternaria alternata is a clinically relevant allergen that is associated with severe and fatal asthma exacerbations. exposure to a. alternata is characterized by a predominant th2 response, b ... | 2016 | 27815425 |
| modelling the effect of temperature, water activity and carbon dioxide on the growth of aspergillus niger and alternaria alternata isolated from fresh date fruit. | to quantify and model the combined effects of temperature (t) (10-40°c), water activity (aw ) (0·993-0·818) and co2 concentration (9·4-55·1%, v/v) on the growth rate of aspergillus niger and alternaria alternata that cause spoilage during the storage and packaging of dates. | 2016 | 27626891 |