| a paradigm for the molecular identification of mycobacterium species in a routine diagnostic laboratory. | the aim of this study was to improve the identification of mycobacterium species in the context of a uk teaching hospital. real-time pcr assays were established to enable the rapid differentiation between mycobacterium tuberculosis (mtb) complex and mycobacterium species other than tuberculosis (mott), followed by 16s rrna gene sequencing for the speciation of mott. real-time pcr assays gave comparable results to those from the reference laboratory. the implementation of these pcr assays using a ... | 2007 | 17446280 |
| [a case of münchausen syndrome with recurrent bacteremia and pr3-anca positivity]. | a 29-year-old woman chiropractor with repeated episodes of bacteremia and positive for cytoplasmic antineutrophil cytoplasmic antibody (c-anca) and antiproteinase-3 (pr3) antibody had an 11-year history of asthma and repeated hospitalization. while hospitalized she developed a spiking nocturnal fever with chills and erythema of the lower leg. her fever resolved spontaneously, but corticosteroid therapy and antibiotics did not effectively reduce her symptoms. plain x-ray film and ct showed pulmon ... | 2007 | 17447478 |
| fishing injury resulting in mycobacterium fortuitum palmar abscess. | | 2007 | 17458567 |
| mycobacterial soft tissue infections in north queensland. | mycobacterial soft tissue infections are a heterogeneous group of infections that usually require a variety of therapeutic methods for cure. north queensland has an environment, which predisposes to several such infections. the aim of this study was to assess the incidence and epidemiology of mycobacterial soft tissue infections in north queensland and to review surgical and non-surgical interventions in these conditions. | 2007 | 17497978 |
| molecular identification by random amplified polymorphic dna analysis of a pseudo-outbreak of mycobacterium fortuitum due to cross-contamination of clinical samples. | | 2007 | 17510279 |
| microbial consortium bioaugmentation of a polycyclic aromatic hydrocarbons contaminated soil. | in this study we evaluated the capacity of a defined microbial consortium (five bacteria: mycobacterium fortuitum, bacillus cereus, microbacterium sp., gordonia polyisoprenivorans, microbacteriaceae bacterium, naphthalene-utilizing bacterium; and a fungus identified as fusarium oxysporum) isolated from a pahs contaminated landfarm site to degrade and mineralize different concentrations (0, 250, 500 and 1000 mg kg(-1)) of anthracene, phenanthrene and pyrene in soil. pahs degradation and mineraliz ... | 2008 | 17572084 |
| in response to: sathiakar paul collison, naresh trehan. native double-valve endocarditis by mycobacterium fortuitum following percutaneous coronary intervention. j heart valve dis 2006;15:836-838. | | 2007 | 17578059 |
| a cluster of rapidly growing mycobacterial peritoneal dialysis catheter exit-site infections. | in this case series, a cluster of 5 consecutive peritoneal dialysis patients with atypical mycobacterial exit-site infections in a single center within 20 months are described. clinical features, treatment, and outcomes are discussed. most patients had been treated with prolonged systemic antibiotic therapy for recurrent bacterial exit-site infections in the preceding months, and all had used topical gentamicin ointment for exit-site infection treatment or prophylaxis. it is postulated that this ... | 2007 | 17591517 |
| application of polymerase chain reaction-based restriction fragment length polymorphism in typing ocular rapid-growing nontuberculous mycobacterial isolates from three patients with postoperative endophthalmitis. | we describe postoperative endophthalmitis caused by rapid-growing nontuberculous mycobacteria (rgntm) in 3 patients after small-incision cataract surgery with intraocular lens (iol) implantation performed elsewhere and referred to us for management. subsequent identification and confirmation was carried out with biochemical tests and polymerase chain reaction-based restriction fragment length polymorphism (pcr-rflp). | 2007 | 17592326 |
| mycobacterium fortuitum pneumonia in a cat and the role of lipid in the pathogenesis of atypical mycobacterial infections. | mycobacterium fortuitum is a saprophytic, fast-growing, nontuberculous, and nonlepromatous mycobacterium that can cause infections in animals and humans. in dogs and cats, it is one of the most common agents of ulcerative dermatitides and panniculitides caused by atypical mycobacteria. in humans, it is frequently found in lipoid pneumonias or contaminated surgical sites. we report a cat with granulomatous pneumonia caused by m fortuitum resembling lipoid pneumonia in humans. the similarity betwe ... | 2007 | 17606521 |
| in-vitro evaluation of the adhesion to polypropylene sutures of non-pigmented, rapidly growing mycobacteria. | the ability of non-pigmented, rapidly growing mycobacteria (nprgm) to attach to polypropylene sutures was evaluated using an in-vitro assay. thirty clinical isolates and five culture collection strains of nprgm, together with staphylococcus epidermidis atcc 35983, were tested. mycobacterium fortuitum and mycobacterium chelonae showed the highest attachment ability, which differed significantly from the results obtained with mycobacterium peregrinum. according to these results, nprgm are able to ... | 2007 | 17608747 |
| injection site abscess due to mycobacterium fortuitum: a case report. | injection abscess is an iatrogenic infection occurring as an isolated case or as cluster outbreak. these infections occur due to contaminated injectables or lapse in sterilisation protocol. while pathogens such as pseudomonas, klebsiella, e. coli, and s. aureus are the usual causative agents, unusual organisms such as mycobacteria, particularly the rapidly growing non-tuberculous mycobacteria (ntm) may cause the abscess. the chances of overlooking these organisms is high unless an acid fast baci ... | 2003 | 17643000 |
| wound infections due to mycobacterium fortuitum after polypropylene mesh inguinal hernia repair. | mycobacterium fortuitum complex is a group of rapidly growing mycobacteria (rgm). these opportunistic pathogens are frequently associated with infections related to surgical procedures involving biomaterials. two cases of mycobacterium fortuitum infection occurred in a prospective study of inguinal hernia prosthesis repairs. these infections differed from those caused by other bacteria in terms of pathogenic mechanisms, clinical manifestation and resistance to both prophylactic and therapeutic a ... | 2007 | 17655974 |
| mycobacterium fortuitum infection masquerading as an orbital mass. | orbital infection with nontuberculous mycobacteria is rare and usually presents as an inflammatory process. we report a case of a 34-year-old male hospital worker with a positive purified protein derivative skin test who had mycobacterium fortuitum infection that presented as an orbital mass causing diplopia. this presentation is unlike previously published reports and demonstrates the importance of orbital biopsy and tissue culture. | 2007 | 17667115 |
| prosthetic joint infection due to rapidly growing mycobacteria: report of 8 cases and review of the literature. | prosthetic joint infection (pji) due to rapidly growing mycobacteria (rgm) is only occasionally encountered in clinical practice. therefore, the optimal clinical management for this condition is unknown. | 2007 | 17712751 |
| ethnobotanical survey and antibacterial activity of some plants used in guinean traditional medicine. | a total of 418 healers have been interviewed in guinea, a coastal country of west africa, ranging between 7 degrees 30 and 12 degrees 30 of northern latitude and 8 degrees and 15 degrees of western longitude. plant species used by the local inhabitants to treat infectious diseases were identified using ethnobotanical, ethnographic and taxonomic methods. during these investigations, 218 plants were registered, of which the following were the most frequently used: erythrina senegalensis, bridelia ... | 2007 | 17825510 |
| cutaneous mycobacterium fortuitum complicating breast reconstruction. | | 2007 | 17825781 |
| mycobacterium fortuitum infection following total knee arthroplasty: a case report and literature review. | although mycobacterium fortuitum is ubiquitous in our environment, infection of total knee arthroplasties with this organism is uncommon. this particular mycobacterium belongs to a group of organisms known as rapidly growing mycobacteria that distinguishes itself from the more typical mycobacterium tuberculosis by their lower virulence and lack of human-to-human transmission. another distinguishing feature is their resistance to almost all traditional anti-tuberculous medications and many antibi ... | 2008 | 17869520 |
| rapidly growing mycobacteria: clinical and microbiologic studies of 115 cases. | we analyzed clinical and microbiologic features of 115 cases involving rapidly growing mycobacteria (rgm) isolated at the university of texas m.d. anderson cancer center, houston (2000-2005) and identified by 16s ribosomal rna gene sequencing analysis. at least 15 rgm species were included: mycobacterium abscessus (43 strains [37.4%]), mycobacterium fortuitum complex (33 strains [28.7%]), and mycobacterium mucogenicum (28 strains [24.3%]) most common, accounting for 90.4%. most m abscessus (32/4 ... | 2007 | 17875513 |
| infections with atypical mycobacteria in renal transplant recipients. | infections due to atypical mycobacteria are infrequent in renal transplant recipients but they cause serious morbidity. these pathogens are common in patients with acquired immune deficiency syndrome (aids). we report four proven cases of infections caused with atypical mycobacteriae from 1997 to 2003, by different organisms namely, m. chelonei, m.fortuitum, m. abcessus and m. terrae in renal transplant recipients. infection with m. terrae documented here is the first occurrence in a renal trans ... | 2007 | 17883113 |
| association of mycobacteria with eales' disease. | eales' disease is an idiopathic disease resulting in retinal neovascularization, recurrent haemorrhages, with or without retinal detachment predominantly affecting healthy young males (97.6%) in the indian subcontinent. inspite of several studies, the aetiology of eales' disease is not clear. the isolation of mycobacterium fortuitum from the aqueous humour of a patient with classical eales' disease, led us to hypothesize that rapid growing nontuberculous mycobacteria (rgntm), particularly m. for ... | 2007 | 17890825 |
| mycobacterium other than tuberculosis (mott) infection: an emerging disease in infliximab-treated patients. | infliximab has revolutionized treatment of rheumatologic diseases and inflammatory bowel disease. however, it increases the risk of tuberculosis. less is known about the development of mycobacterium other than tuberculosis (mott) infection. we review the literature on non-tuberculous mycobacterial infections in infliximab-treated patients and report the first case of disseminated mycobacterium avium complex in an infliximab-treated patient complicated by immune reconstitution inflammatory syndro ... | 2007 | 17920687 |
| antimicrobial lexitropsins containing amide, amidine, and alkene linking groups. | the synthesis and properties of 80 short minor groove binders related to distamycin and the thiazotropsins are described. the design of the compounds was principally predicated upon increased affinity arising from hydrophobic interactions between minor groove binders and dna. the introduction of hydrophobic aromatic head groups, including quinolyl and benzoyl derivatives, and of alkenes as linkers led to several strongly active antibacterial compounds with mic for staphylococcus aureus, both met ... | 2007 | 17960927 |
| [renal mycobacteriosis]. | there is a number of specific infections due to opportunistic mycobacteria which normally exist as environmental saprophytes. among them, renal mycobacteriosis is a disease similar to renal tuberculosis. the obvious causative agents are some mycobacteria: mycobacterium chelonei, mycobacterium fortuitum, mycobacterium xenopi, mycobacterium kansasii, mycobacterium avium complex, and mycobacterium simiae. it is not easy to prove that a renal disease is of mycobacterial origin. we suggest some crite ... | 1994 | 17972827 |
| molecular systematics support the revival of mycobacterium salmoniphilum (ex ross 1960) sp. nov., nom. rev., a species closely related to mycobacterium chelonae. | mycobacterial infections in fish are usually attributed to strains of mycobacterium marinum, mycobacterium chelonae and mycobacterium fortuitum. bacteria identified as m. chelonae have been isolated numerous times from salmonid fishes. recently, this bacterium has been associated with salmon mortalities in the aquaculture industry. an m. chelonae-like species from salmon, 'mycobacterium salmoniphilum', was described in 1960. however, the species name lost standing in nomenclature when it was omi ... | 2007 | 17978213 |
| evaluation of the broth microdilution method using 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride for rapidly growing mycobacteria susceptibility testing. | as the incidence of nontuberculous mycobacterial infection has been increasing recently in korea, the importance of drug susceptibility test for clinical isolates of mycobacteria has become larger. in this study we determined the antimicrobial susceptibility patterns of clinical isolates of m. fortuitum and m. abscessus in korea, and evaluated the efficacy of a modified broth microdilution method using 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride (stc), in terms of its ability to provide accu ... | 2007 | 17982223 |
| clinical significance of mycobacterium fortuitum isolated from respiratory specimens. | although mycobacterium fortuitum is not an uncommon organism among the non-tuberculous mycobacteria isolated from respiratory specimens, its clinical significance had not been well studied. | 2008 | 17997087 |
| cluster of mycobacterium fortuitum prosthetic joint infections. | mycobacterium fortuitum is a member of the rapidly growing nontuberculous mycobacteria. although mortality is rare from m. fortuitum, morbidity depends on the localized site of infection. m. fortuitum is ubiquitous in the environment and has been reported to cause infections of prosthetic devices. there have been seven previously reported cases of prosthetic joint infections due to m. fortuitum. this article presents three additional cases of postoperative joint infections due to m. fortuitum. a ... | 2007 | 18053402 |
| arthroplasty tourism. | the practice of "medical tourism" is gaining popularity. lower costs and shorter waiting times are compelling motivating factors. there are also increasing commercial interests promoting medical tourism. there are very limited clinical data to support or refute this practice. however, medical tourism breaks important elements in the traditional health care model, including patient selection, continuity of care, and practice auditing. when complications arise, challenges specific to medical touri ... | 2007 | 18072912 |
| generation of resistant mutants of mycobacterium chelonae and mycobacterium fortuitum after exposure to subinhibitory concentrations of clarithromycin and moxifloxacin. | | 2007 | 18073162 |
| mycobacterium fortuitum keratitis. | we report a case of mycobacterial keratitis characterized by apparently spontaneous onset, delayed diagnosis, and eventually necessitating evisceration inspite of systemic antibiotics and repeated corneal grafts. | 2007 | 18087102 |
| the changing pattern of nontuberculous mycobacterial disease. | nontuberculous mycobacteria are human opportunistic pathogens whose source of infection is the environment. these include both slow-growing (eg, mycobacterium kansasii and mycobacterium avium) and rapid-growing (eg, mycobacterium abscessus and mycobacterium fortuitum) species. transmission is through ingestion or inhalation of water, particulate matter or aerosols, or through trauma. the historic presentation of pulmonary disease in older individuals with predisposing lung conditions and in chil ... | 2003 | 18159470 |
| cardiac device infections due to mycobacterium fortuitum. | two cases of cardiac device infection due to mycobacterium fortuitum are reported along with a discussion of their clinical management. long-term therapy and removal of the infected device is needed. the slow progression and absence of systemic signs and symptoms suggest a low pathogenicity of m fortuitum. | 2005 | 18159541 |
| mycobacterium setense sp. nov., a mycobacterium fortuitum-group organism isolated from a patient with soft tissue infection and osteitis. | a gram-positive, rod-shaped acid-fast bacterium was isolated from a patient with a post-traumatic chronic skin abscess associated with osteitis. morphological analysis, 16s rrna, hsp65, soda and rpob gene sequence analysis, cell-wall fatty acid and mycolic acid composition analyses and biochemical tests showed that the isolate, designated abo-m06(t), belonged to the genus mycobacterium. its phenotype was unique and genetic and phylogenetic findings suggest that strain abo-m06(t) represents a nov ... | 2008 | 18218954 |
| catheter-related bloodstream infections caused by rapidly growing nontuberculous mycobacteria: a case series including rare species. | rapidly growing nontuberculous mycobacteria (rgms) are responsible for a variety of clinical syndromes in humans including catheter-related blood stream infections (crbsis). recently, we identified a cluster of rgm-associated crbsi at our institution. we describe the epidemiologic and clinical patterns associated with these infections. we conducted a retrospective single-center review of rgm crbsi between may 2004 and june 2005. rgms isolated from blood cultures of 6 patients included mycobacter ... | 2008 | 18294801 |
| antimycobacterial polyacetylenes from levisticum officinale. | no conflicts of interest concerning financial matters or personal relationships exist between the authors and those who might bias this work. the present work is in part included the phd thesis of a. schinkovitz (university of graz) but has not been published elsewhere previously. the dichloromethane extract of the roots of levisticum officinale l. (apiaceae) exhibited significant antimycobacterial activity against mycobacterium fortuitum and mycobacterium aurum in a microtiter plate dilution as ... | 2008 | 18350523 |
| mycobacterial infections in human immuno-deficiency virus seropositive patients: role of non-tuberculous mycobacteria. | there is high prevalence of tuberculosis in patients with hiv infection; hence the role of non-tuberculous mycobacteria (ntm) in hiv patients has always been undermined. ntm may be responsible for clinical disease in a substantial number of immuno-compromised hiv sero-positive individuals even in a country endemic for mycobacterium tuberculosis (m. tuberculosis). the study was designed to look for the contribution of ntm to morbidity in hiv seropositive patients. | 2008 | 18361308 |
| mycobacterium fortuitum and anaerobic breast abscess following nipple piercing: case presentation and review of the literature. | body piercing has become increasingly prevalent. we describe a case of breast infection with combined mycobacteria and anaerobe following nipple piercing, and review the literature. | 2008 | 18407050 |
| [case of pneumothorax associated with pulmonary mycobacterium fortuitum infection]. | a 39-year-old man with dyspnea was revealed to have severe pneumothorax and received partial resection of the left upper lobe after unsuccessful drainage. necrotizing epitheloid granuloma was found in the resected lung and mycobacterium fortuitum was detected from the lesion. chemotherapy with levofloxacin and clarithromycin was started one year after surgery because of the newly found nodular shadow near the lesion. the case experienced pyothorax due to pulmonary tuberculosis three years before ... | 2008 | 18411763 |
| antimicrobial resistance of rapidly growing mycobacteria in western taiwan: smart program 2002. | to understand the resistance patterns of rapidly growing mycobacteria (rgm) in taiwan, antimicrobial resistance of clinical isolates was determined as part of the smart (surveillance from multicenter antimicrobial resistance in taiwan) program. | 2008 | 18445541 |
| occurrence of mycobacterium spp. in ornamental fish in italy. | the occurrence of mycobacterium spp. in freshwater and marine ornamental fish was studied in italy from june 2002 to may 2005. two surveys were carried out, one of aquarium fish sent to the laboratory for diagnosis, and the other of prevalence of infection by mycobacteria in ornamental fish imported into italy. bacterial isolation was carried out from the spleen, kidney and liver, and the isolates were subsequently identified by biochemical tests. in the first survey, 387 fish were examined and ... | 2008 | 18471099 |
| large subcutaneous abscesses caused by mycobacterium fortuitum infection. | | 2008 | 18480951 |
| mycobacterium fortuitum infection following primary achilles tendon debridement with flexor hallucis longus augmentation: a case report. | mycobacterium fortuitum (m. fortuitum), a rapidly growing non-tuberculous mycobacterium is a well-recognized, yet uncommon cause of soft tissue infection. the incidence of post surgical wound infections from this organism is increasing. the presentation of infection is atypical and failure to consider this pathogen can cause diagnostic delay and increased morbidity. achilles tendon debridement with fhl augmentation is commonly used in patients with chronic achilles tendinosis. wound-edge necrosi ... | 2008 | 18510912 |
| bilateral knee periprosthetic infection with mycobacterium fortuitum. | periprosthetic infections after total joint arthroplasty are infrequent but potentially devastating complications. gram-positive bacteria is the typical causative organism. however, uncommon sources such as mycobacterium fortuitum have been documented in the literature. we report a case, the first to our knowledge, of bilateral infections involving this organism after total knee arthroplasty. m. fortuitum is notoriously resistant to many standard antibacterial medications, and a delay in initial ... | 2008 | 18534520 |
| pyrido-1,2-thiazines and their in vitro antibacterial evaluation. | a series of known and newly synthesized pyrido-1,2-thiazine derivatives of type 3-6 were evaluated against strains of mycobacterium fortuitum (pcm 672) and staphylococcus aureus (pcm 2602) the pilot experiments showed that most of the compounds in initial in vitro microbiological evaluation were not efficient antibacterial agents, but unexpectedly promoted replication of the microorganisms in the range of 10-50%. | 2008 | 18536176 |
| late-onset posttraumatic skin and soft-tissue infections caused by rapid-growing mycobacteria in tsunami survivors. | in the tsunami catastrophe in thailand in 2004, several thousand swedish tourists were injured, with contaminated crush trauma of the legs being the main cause of injury among the survivors. | 2008 | 18549312 |
| [susceptibility to antimicrobial agents of rapidly growing mycobacteria]. | rapidly growing mycobacteria are often associated with human diseases. we investigated the in vitro susceptibilities of 40 isolates to six antimicrobial agents: 17 mycobacterium fortuitum, 11 m. chelonae and 12 m. abscessus isolated from several human sources: 29 respiratory secretions, 5 cutaneous abscesses, 4 corneal ulcers and 2 urine samples of patients treated at "hospital puerta del mar" (cádiz). susceptibility studies were determined by the broth microdilution method for amikacin, clarith ... | 2007 | 18563216 |
| therapy of environmental mycobacterial infections. | environmental mycobacteria are the causative factors of an increasing number of infections worldwide. cutaneous infections as a result of environmental mycobacteria are often misdiagnosed, and their treatment is difficult because these agents can show in vivo and in vitro multidrug resistance. the most common environmental mycobacteria that can cause cutaneous infections are mycobacterium fortuitum and mycobacterium marinum. all mycobacteria are characterized by low pathogenicity and they can co ... | 2008 | 18564246 |
| transcriptional analysis of mycobacterium fortuitum cultures upon hydrogen peroxide treatment using the novel standard rrna-p1. | the ability of an intracellular pathogen to establish infection depends on the capacity of the organism to survive and replicate inside the host. mycobacterium fortuitum is a bacteria that contains genes involved in the detoxification of the oxygen reactive species such as those produced by the host during the infection. in this work, we investigate the effects of hydrogen peroxide on the transcription and expression of these genes by developing a real time quantitative pcr technique (qrt-pcr) u ... | 2008 | 18565220 |
| rapid speciation of 15 clinically relevant mycobacteria with simultaneous detection of resistance to rifampin, isoniazid, and streptomycin in mycobacterium tuberculosis complex. | to design and standardize an in-house reverse line blot hybridization (rlbh) assay for the accurate identification of 15 clinically relevant species of mycobacteria and for the detection of drug resistance to rifampin (rif), isoniazid (inh), and streptomycin (str) in mycobacterium tuberculosis complex (mtb). | 2009 | 18565777 |
| a study of mycobacterial species causing lymphadenitis. | this prospective study evaluated the non-tuberculous mycobacteria (ntm) cases of lymphadenitis. a total of 76 isolates of mycobacteria were obtained from 200 lymph node aspirates suspected of tuberculosis, 74 of which were mycobacterium tuberculosis, one was mycobacterium fortuitum and one mycobacterium kansasii. these results highlight the importance of ntm in hiv-negative patients as a case of lymphadenitis, and indicates the re-emergence of ntm as potential lymph node pathogens in this part o ... | 2008 | 18567452 |
| importation of mycobacteriosis with ornamental fish: medico-legal implications. | mycobacterium fortuitum, as well as mycobacterium marinum and mycobacterium chelonae, are the etiological agents of fish mycobacterioses. mycobacteriosis has been reported to affect a wide range of freshwater and marine fish species, suggesting an ubiquitous distribution, and can cause zoonotic infections (known as "fish tank granuloma" or "swimming pool granuloma") in humans exposed to fish and contaminated water. infection in human consists of nodular cutaneous lesions that can progress to ten ... | 2008 | 18571116 |
| purified compounds and extracts from euclea species with antimycobacterial activity against mycobacterium bovis and fast-growing mycobacteria. | naphthoquinones and other compounds with antimycobacterial activity against mycobacterium tuberculosis have previously been isolated from euclea species. in this study, several constituents of euclea natalensis and e. undulata, as well as organic extracts of the leaves, were assessed for efficacy against the zoonotic pathogen, mycobacterium bovis. also included in the battery of test organisms were m. bovis bcg and the fast-growing species m. smegmatis and m. fortuitum. the acetone extract of e. ... | 2008 | 18591787 |
| mycobacterium fortuitum infection interference with mycobacterium bovis diagnostics: natural infection cases and a pilot experimental infection. | mycobacterium fortuitum and at least 1 unidentified species of soil mycobacteria were isolated from lymph nodes from 4 of 5 african buffalo (syncerus caffer) that had been culled because of positive test results using the bovigam assay. the buffalo were part of a group of 16 free-ranging buffalo captured in the far north of the kruger national park (south africa) assumed to be free of bovine tuberculosis. no mycobacterium bovis was isolated. to investigate the possible cause of the apparent fals ... | 2008 | 18599858 |
| drug susceptibility of the mycobacterium genus: in vitro tests and clinical implications. | this review describes the mechanisms of drug resistance of the most clinically relevant mycobacteria and the methods that have been used for studying drug susceptibility (pnenotype, genotype and in vivo tests) and it describes the more important resistance mechanisms to the drugs. also, this review describes the relationship between microbiological and pharmacological data and the importance of latency -stationary phase- in mycobacteria. current clinical guidelines on the treatment of tuberculos ... | 2006 | 18666752 |
| chronic postoperative wound infection caused by myocobacterium fortuitum complex. | mycobacterium fortuitum in a rapidly growing atypical mycobacteia, sometimes associated with nosocomial infections in human. these infections are often difficult to identify; and treat even after indentification. we report here a case of chronic post operative wound infection due to m. fortuitum. | 2007 | 18697600 |
| microbial o-methylation of the flame retardant tetrabromobisphenol-a. | we demonstrated the o-methylation of tetrabromobisphenol-a (tbbpa) [4,4'-isopropylidenebis (2,6-dibromophenol)] to its mono- and dimethyl ether derivatives by microorganisms present in different sediments. a most probable number assay of a marsh sediment suggested that up to 10% of the total aerobic heterotrophs may be capable of o-methylation. although tbbpa dimethyl ether is not produced in industry, it has been detected in terrestrial and aquatic sediments. our study supports the hypothesis t ... | 2008 | 18754475 |
| [treatment of cutaneous infections due to mycobacterium fortuitum: two cases]. | cutaneous infections due to mycobacterium fortuitum, a rapidly growing environmental mycobacteria, are often iatrogenic, resulting from surgery or injection. we report two cases following plastic surgery and describe the outcome after surgery and antibiotics. | 2008 | 18789296 |
| refractory pneumonia in a mexican american infant. | | 2010 | 18832546 |
| surgical site infection due to mycobacterium peregrinum: a case report and literature review. | mycobacterium peregrinum is a species included in the mycobacterium fortuitum complex, a member of the group of rapidly growing non-tuberculous mycobacteria (rgm). only a few cases of infection with m. peregrinum have been reported, and no relevant review has been published. | 2009 | 18848484 |
| a transposon insertion mutant of mycobacterium fortuitum attenuated in virulence and persistence in a murine infection model that is complemented by rv3291c of mycobacterium tuberculosis. | mycobacterium fortuitum is a non-tubercular fast growing pathogenic mycobacteria whose virulence factors have not been studied. infection of m. fortuitum atcc 6841 in a murine infection model leads to spinning of the head in 8-12 days after infection, 20-25% mortality and a constant bacillary load in the kidney of mice, suggesting persistence. from a tnphoa insertion library, a mutant mt13 was isolated which was attenuated in virulence with lesser bacterial burden, milder and delayed spinning of ... | 2008 | 18930129 |
| bilateral sporotrichoid lymphocutaneous dermatosis in a drug abuser: case report and review of the literature. | bilateral sporotrichoid mycobacterial cutaneous infection is unusual and has been reported in only three cases involving different species and with an unknown route of infection in the literature.we report a case of bilateral sporotrichoid dermatosis in an immunocompetent patient with a history of intravenous heroin injection before development of the skin lesions. both special stain and culture of biopsy specimen were negative. finally, mycobacterium fortuitum was identified by a polymerase cha ... | 2008 | 18973406 |
| cutaneous infection with mycobacterium fortuitum: an unusual presentation. | cutaneous infection with rapidly growing mycobacteria is uncommon and its diagnosis can be missed unless there is strong clinical suspicion coupled with microbiological confirmation. we report a case of localized recurrent soft tissue swelling of the foot by mycobacterium fortuitum in a healthy adult male. the case is being reported for its uncommon clinical presentation and the associated etiological agent. the patient recovered completely following therapy with amikacin and clarithromycin. | 2008 | 18974500 |
| incidence of nontuberculous mycobacteria in four hot water systems using various types of disinfection. | the objective of this study was to determine the incidence of nontuberculous mycobacteria (ntm) in hot water systems of 4 selected hospital settings. the hospitals provided the following types of disinfection for their hot water systems: hydrogen peroxide and silver, thermal disinfection, chlorine dioxide, and no treatment (control). in each building, 6 samples were collected from 5 sites during a 3 month period. ntm were detected in 56 (46.7%) of 120 samples; the cfu counts ranged from 10 to 16 ... | 2008 | 18997845 |
| [clinical features of pulmonary disease caused by mycobacterium fortuitum]. | we analyzed clinical and microbiological features of six cases involving mycobacterium fortuitum isolated from sputum or surgical lung specimen. patients were five men and one woman with an average age of 59. four cases had a history of pulmonary tuberculosis and three had nontuberculous mycobacterial lung disease. three out of six cases had underlying chronic obstructive pulmonary disease. diabetes mellitus was complicated in five cases. all diseases were in the upper lobes of either lung. clin ... | 2008 | 19044027 |
| mycobacterium fortuitum infection in continuous ambulatory peritoneal dialysis. | mycobacterium fortuitum group species is an atypical rapidly growing nontuberculous mycobacterium. it has been increasingly recognized as a potential pathogen mostly encountered in skin and soft tissue infections. rarely, however, it has been associated with catheter-related infections, either central venous lines or peritoneal dialysis catheters. in this report we describe 2 patients maintained on continuous ambulatory peritoneal dialysis who developed mycobacterium fortuitum peritonitis and a ... | 2008 | 19049716 |
| synthesis and studies on antibacterial activity of pyrido[3,2-e]-1,2-thiazines and related derivatives. | twenty of the known and newly synthesized derivatives of pyrido-1,2-thiazine derivatives 3-7, which represent a novel class of potential antibacterial agents, were evaluated against strains of mycobacterium fortuitum (pcm 672) and staphylococcus aureus (pcm 2602). the pilot experiments showed that the compounds in an initial in vitro microbiological evaluation were not efficient antibacterial agents, whereas some of them unexpectedly promoted replication of the microorganisms in the range of 10- ... | 2008 | 19051602 |
| [case of urinary mycobacterium fortuitum in a patient with urinary tract tuberculosis posttreatment]. | a 70-year-old male who complained of urinary frequency and a feeling of incomplete emptying was admitted to our hospital. imaging findings showed dilation of the left renal pelvis and ureter. he was diagnosed as having urinary tuberculosis because a positive urinary mycobacterium tuberculosis result was obtained by polymerase chain reaction (pcr). he was treated with a combination of the antituberculosis agents isoniazid, rifampicin, pyrazinamide and ethambutol for six months. the symptoms and p ... | 2008 | 19068730 |
| [hixozide, a novel combined antituberculosis preparation]. | | 2008 | 19069176 |
| cutaneous atypical mycobacteriosis after ultrasound hydrolipoclasia treatment. | | 2009 | 19076204 |
| [microbiological properties of m. porcinum isolated from a patient with impairments in il-12/ifn-gamma pathway]. | mycobacterium porcinum has been successfully isolated from the patient with abnormal signal transduction pathway of il12/ifn-gamma. the properties of each bacterium were determined by conventional identification methods, dna sequencing analysis and mic assay. | 2008 | 19086435 |
| recombinant mycobacterium smegmatis mc(2)155 vaccine expressing outer membrane protein 26 kda antigen affords therapeutic protection against helicobacter pylori infection. | orally administered recombinant mycobacterium smegmatis (rm. smegmatis) vaccines represent an attractive option for mass vaccination programmes against various infectious diseases. therefore, in the present study, we evaluated the capacity of the outer membrane protein 26kda antigen (omp26) of helicobacter pylori (h. pylori) to induce therapeutic protection against h. pylori infection in mice. omp26 was cloned and expressed in m. smegmatis mc(2)155 as a fusion with the mycobacterium fortuitum be ... | 2009 | 19111590 |
| emerging mycobacteria spp. in cooling towers. | | 2009 | 19116072 |
| screening for sterilizing activity of antibiotic combinations in an acid model of rapidly growing mycobacteria during the stationary phase of growth. | in view of the problems of correlation between the data provided by classical microbiological studies and clinical response, we designed an in vitro method to screen for the sterilizing activity of various antibiotics, individually or in combinations, against clinical isolates of various rapidly growing mycobacteria in the stationary phase. | 2009 | 19155619 |
| chronic meningoencephalomyelitis due to mycobacterium fortuitum in an immunocompetent patient. | | 2008 | 19156495 |
| components derived from pelargonium stimulate macrophage killing of mycobacterium species. | to determine the capacity of extracts of pelargonium reniforme and pelargonium sidoides, plants of the geraniaceae family, to stimulate the uptake and killing of mycobacteria by murine macrophages and to identify the constituents that are responsible. | 2009 | 19191950 |
| clinical outcome of cutaneous rapidly growing mycobacterial infections in cats in the south-eastern united states: a review of 10 cases (1996-2006). | cutaneous infection caused by rapidly growing mycobacteria is a relatively uncommon condition in cats, with variable response rates to surgical debulking and aggressive antibiotic therapy. to date, there have been very few case reports of this disease, especially in the united states. this study reviews a series of cases of cats with rapidly growing cutaneous mycobacterial infections from the south-eastern united states. a majority of the cats were spayed female domestic shorthairs. the median a ... | 2009 | 19201237 |
| characterisation of porin genes from mycobacterium fortuitum and their impact on growth. | highly pathogenic mycobacteria like mycobacterium tuberculosis are characterised by their slow growth and their ability to reside and multiply in the very hostile phagosomal environment and a correlation between the growth rate of mycobacteria and their pathogenicity has been hypothesised. here, porin genes from m. fortuitum were cloned and characterised to address their impact on the growth rate of fast-growing and pathogenic mycobacteria. | 2009 | 19203364 |
| delayed silicone breast implant infection with mycobacterium avium-intracellulare. | mycobacterial breast implant infection is a rare complication after augmentation mammaplasty. a review of the literature demonstrates multiple examples of breast implant infection with mycobacterium fortuitum, but only rare discussion of mycobacterium avium-intracellulare (mac). the authors report an unusual case of mac breast implant infection in a patient with a complex surgical history. | 2007 | 19341643 |
| development of a simple and low-cost real-time pcr method for the identification of commonly encountered mycobacteria in a high throughput laboratory. | to facilitate efficient identification of commonly encountered mycobacteria species (mycobacterium tuberculosis, mycobacterium avium, mycobacterium intracellulare, mycobacterium fortuitum complex, mycobacterium chelonae/abscessus, mycobacterium kansasii, mycobacterium gordonae) in high throughput laboratories, a 16s rdna sequence based real-time pcr assay was developed and evaluated. | 2009 | 19426272 |
| mycobacterial di-o-acyl trehalose inhibits th-1 cytokine gene expression in murine cells by down-modulation of mapk signaling. | protection against tuberculosis (tb) is based on cell-mediated immune responses. tb is often characterized by immunological dysfunction of peripheral blood mononuclear cells, especially at chronic stages. lipids from the mycobacterium tuberculosis cell wall have been shown to produce various suppressive effects on cell-mediated immunity. the cell-surface lipid di-o-acyl-trehalose (dat) is able to inhibit t-cell proliferation and cytokine secretion in cells from naïve mice. in the present study, ... | 2010 | 19450894 |
| molecular characterisation of mycobacterium bovis isolates from cattle carcases at a city slaughterhouse in uganda. | during a period of eight months, the carcases of 16,800 slaughter cattle were inspected at a city abattoir in uganda. eighty-seven of them had tuberculosis-like lesions and tissue samples were cultured. only 17 cultures yielded acid-fast bacilli; 11 of them were confirmed as mycobacterium bovis and six as non-tuberculous mycobacteria (ntm). genotype mycobacterium assays on the six ntm identified two as mycobacterium fortuitum and one as mycobacterium intracellulare, but three were unidentified. ... | 2009 | 19465755 |
| sequelae of rapid growing mycobacteria otomastoiditis in a child. | | 2009 | 19528410 |
| mesotherapy and cutaneous mycobacterium fortuitum infection. | cutaneous infections caused by mycobacterium fortuitum usually are a complication of trauma or postsurgical wounds. | 2009 | 19538379 |
| nontuberculous mycobacteria isolated during the treatment of pulmonary tuberculosis. | the significance of nontuberculous mycobacteria (ntm) isolated from a patient during therapy for pulmonary tuberculosis (tb) is uncertain. we investigated the frequency and clinical significance of ntm isolated from patients receiving anti-tb treatment. | 2009 | 19576745 |
| detection of lfra and tap efflux pump genes among clinical isolates of non-pigmented rapidly growing mycobacteria. | this study was performed to detect lfra and tap efflux pumps among clinical isolates of non-pigmented rapidly growing mycobacteria (nprgm). gene detection was performed using polymerase chain reaction (pcr) with specific primers designed for each gene. susceptibility of the strains to doxycycline, tigecycline and ciprofloxacin was analysed using the broth microdilution reference technique. in total, 166 clinical isolates were included in the study. the lfra gene was detected in four strains (2.4 ... | 2009 | 19665358 |
| environmental mycobacteria from alpine and subalpine habitats. | abstract mycobacteria were isolated from a variety of materials such as soil, peat, humus, tufa, sphagnum, and wood, collected in alpine and subalpine habitats. mycobacteria, including mycobacterium kansasii, mycobacterium malmoense, mycobacterium szulgai, mycobacterium gordonae, mycobacterium terrae, mycobacterium chelonae, and mycobacterium fortuitum were recovered from 69 of 81 (85%) samples. all of the isolates were recovered on medium incubated at 20 and 30 degrees c. none were recovered if ... | 2004 | 19712284 |
| in vitro synergic effect of beta-lapachone and isoniazid on the growth of mycobacterium fortuitum and mycobacterium smegmatis. | nontuberculous mycobacteria are ubiquitous and saprophytic organisms that have been implicated in a wide spectrum of diseases due to an increasing number of immunocompromised patients. the natural resistance of atypical mycobacteria to classical antituberculous drugs has encouraged research into new chemotherapeutic agents and drug combinations. the aim of this study was to determine the in vitro antimycobacterial activities of (2)-lapachone alone and in combination with isoniazid against mycoba ... | 2009 | 19722080 |
| non-granulomatous mycobacterium fortuitum infection masquerading as malignant lymphoma-a report of two cases. | | 2009 | 19723154 |
| mycobacterium fortuitum infection after anterior cruciate ligament reconstruction using a polylactic acid bioabsorbable screw: case report. | we report a case of pretibial sinus and abscess after anterior cruciate ligament reconstruction using a polylactic acid tricalcium phosphate bioabsorbable screw for tibial fixation. mycobacterium fortuitum was identified as the pathogen after specific mycobacterial cultures were obtained from operative specimens. m. fortuitum is a known but rare cause of periprosthetic infection. diagnosis is often delayed as routine microbiological cultures do not utilise specific culture requirements for mycob ... | 2010 | 19744856 |
| mycobacterium fortuitum abdominal wall abscesses following liposuction. | we describe here a case of abdominal abscesses due to mycobacterium fortuitum following liposuction. the abscesses developed three months after the procedure and diagnosis was delayed for five months. the clues for diagnosis were persistent pus discharge in spite of broad spectrum antibiotics and failure to grow any organisms on routine culture. this condition has been rarely reported; however, the increasing number of liposuction procedures done and awareness among physicians will probably resu ... | 2008 | 19753203 |
| antimycobacterial terpenoids from juniperus communis l. (cuppressaceae). | juniperus communis is a plant which has been reported as a traditional cure for tuberculosis (tb) and other respiratory diseases. | 2009 | 19755141 |
| [radiographic findings of pulmonary nontuberculous mycobacteriosis other than mycobacterium avium complex]. | almost all nontuberculous mycobacteria (ntm) cause opportunistic infection. therefore, the radiographic findings of ntm have a tendency of nonspecific patterns modifying the predisposing conditions or diseases and we could not extract species specific radiographic characterizations in that situations. in this review, the ntm cases without predisposing conditions or diseases are submitted essentially. mycobacterium kansasii cases show more or less the same patterns with tb cases. mycobacterium fo ... | 2009 | 19764463 |
| molecular identification of rapidly growing mycobacteria isolates from pulmonary specimens of patients in the state of pará, amazon region, brazil. | we isolated 44 strains of rapidly growing mycobacteria (rgm) from 19 patients with pulmonary infections assisted at the instituto evandro chagas (pará, brazil) from 2004 to 2007. identification at the species level was performed by pcr restriction fragment length polymorphism analysis (pra) of a 441 bp hsp65 fragment and partial 16s rrna, hsp65, and rpob gene sequencing. genotyping by pra yielded 3 digestion patterns: one identical to mycobacterium abscessus type i (group i); another to m. absce ... | 2009 | 19796904 |
| [assessment of in vitro susceptibility to antimicrobials of rapidly growing mycobacteria by e-test]. | rapidly growing mycobacteria (rgm) are considered opportunistic pathogens. an increasing number of post traumatic or surgical infections are caused by these microorganisms. | 2009 | 19802419 |
| an outbreak of mycobacterium fortuitum cutaneous infection associated with mesotherapy. | we describe an outbreak of mycobacterium fortuitum cutaneous infections associated with mesotherapy in la rioja, spain. | 2010 | 19840199 |
| myocardial abscess and bacteremia complicating mycobacterium fortuitum pacemaker infection: case report and review of the literature. | a case of pacemaker infection complicated by bacteremia and myocardial abscess caused by mycobacterium fortuitum is reported and 9 other cases of pacemaker infection associated with rapidly growing mycobacteria are reviewed. most cases developed within 6 months from implantation suggesting nosocomial acquisition. wound discharge, fever, and pain at generator site were the most common presenting features. at presentation they had a median duration of symptoms of 34 days. concomitant bacteremia wa ... | 2009 | 19859019 |
| commercial dna probes for mycobacteria incorrectly identify a number of less frequently encountered species. | although commercially available dna probes for identification of mycobacteria have been investigated with large numbers of strains, nothing is known about the ability of these probes to identify less frequently encountered species. we analyzed, with inno lipa mycobacteria (innogenetics) and with genotype mycobacterium (hein), 317 strains, belonging to 136 species, 61 of which had never been assayed before. inno lipa misidentified 20 taxa, the majority of which cross-reacted with the probes speci ... | 2010 | 19906898 |
| a sensitive fret probe assay for the selective detection of mycobacterium marinum in fish. | mycobacterium marinum is the causative agent of mycobacteriosis in wild and cultured fish and of atypical infection in humans. for the diagnosis of m. marinum, cultural and traditional polymerase chain reaction (pcr) methods are currently used. however, these protocols, although able to discriminate within mycobacterium spp., have proved to be time-consuming or difficult to carry out. for this reason, the aim of this study was to obtain a rapid and specific diagnostic tool to quantify fish mycob ... | 2010 | 19912457 |
| current treatment of atypical mycobacteriosis. | atypical mycobacteria are a heterogeneous group of organisms that are of increasing importance because of the growing number of infections they cause. this rising rate of infection is due mainly to the increase in the number of susceptible (and especially immunosuppressed) patients. | 2009 | 19929702 |