| influence of the ph-value on the growth of staphylococcus epidermidis, staphylococcus aureus and propionibacterium acnes in continuous culture. | a cutaneous isolate of staphylococcus epidermidis, staphylococcus aureus and propionibacterium acnes was grown in continuous culture at varying ph-values ranging from 5.0 to 8.5. in terms of the specific growth rate as well as the bacterial density during the plateau phase there were remarkable differences. in particular, propionibacterium acnes grew much better in the ph 6.0 to 7.0 range than in a more acidic or alkaline milieu. staphylococcus epidermidis resembled staphylococcus aureus showing ... | 1992 | 1503605 |
| murine kupffer cells and hepatic natural killer cells regulate tumor growth in a quantitative model of colorectal liver metastases. | this investigation aimed to develop a biologically relevant murine model of colorectal liver metastases and determine if kupffer cells (kc) and hepatic natural killer cells (hnkc) regulate tumor growth. the model involves the injection of murine colon adenocarcinoma 26 (mca 26) tumor cells into the portal vein of female-specific pathogen-free balb/c mice. metastases developed in all animals, and the growth was limited entirely to the liver. to determine if kc and hnkc control the development of ... | 1992 | 1505122 |
| bacteriology of ophthalmic infections with special reference to anaerobes. | a total of 138 eye specimens were processed for aerobic and anaerobic cultures. clinical data were obtained from 50 patients with unilateral ophthalmic infection. cultures from the uninfected eye of 38 of these 50 patients were also processed for comparison. in addition, 50 cultures were obtained from one or both eyes of 30 healthy controls who had no eye infection. anaerobes and aerobes were isolated from infected eyes of 6 (12%) and 37 (74%) patients respectively. no growth was observed in inf ... | 1992 | 1506066 |
| development of cutaneous microflora in premature neonates. | coagulase-negative staphylococci (c-ns) are a frequent cause of bacteraemia in premature neonates. it is likely that the strains of c-ns causing bacterial sepsis in premature neonates have their origin on the patient's skin surface. we have studied the quantitative development of the skin microflora at eight sites on premature neonates. a swab wash method was used to sample and enumerate the cutaneous microflora of premature neonates admitted to an intensive care unit with respiratory distress s ... | 1992 | 1519978 |
| antibacterial activity of crinitol and its potentiation. | an acyclic diterpene alcohol, crinitol [1], was identified in a marine brown alga, sargassum tortile, as the principal antibacterial agent against gram-positive bacteria, among which propionibacterium acnes was most sensitive and, staphylococcus aureus was least. to enhance its activity, crinitol was combined with several antioxidants, which presumably retard oxidative destruction of this molecule which possesses two easily oxidizable allylic alcohol groups. two synthetic antioxidants, bha (buty ... | 1992 | 1522419 |
| the importance of methionine residues for the catalysis of the biotin enzyme, transcarboxylase. analysis by site-directed mutagenesis. | almost all biotin enzymes contain the conserved tetrapeptide ala-met-bct-met (bct, n epsilon-biotinyl-l-lysine). in the 1.3 s biotinyl subunit of transcarboxylase (tc), this sequence is present between positions 87 and 90. the conserved nature of these amino acids implies a critical role in the function of biotin enzymes. in order to examine the role of these conserved amino acids, point mutations in the gene encoding the 1.3 s subunit have been made by site-directed mutagenesis to generate a87g ... | 1992 | 1526981 |
| enumeration of subgingival species on primary isolation plates using colony lifts. | this study evaluated the feasibility of using a colony lift method and dna probes to enumerate bacterial species cultured on primary isolation plates. fourteen digoxigenin-labeled whole chromosomal dna probes representing 12 subgingival species were validated by hybridization with colony lifts prepared from 249 reference strains of 51 species grown on trypticase soy agar plates supplemented with 5% sheep blood. colonies of reference strains were lifted onto nytran filters from plates and treated ... | 1992 | 1528619 |
| isolation and properties of the capnocytophaga ochracea bacteriocin. | a bacteriocin from a subgingival plaque isolate of capnocytophaga ochracea was purified and characterized. it was isolated from cell extract and had a molecular weight of 100,000. streptococcus sanguis, streptococcus mitis, streptococcus mutans and propionibacterium acnes were susceptible to the bacteriocin. | 1992 | 1528638 |
| in vitro activities of three semisynthetic amide derivatives of teicoplanin, mdl 62208, mdl 62211, and mdl 62873. | mdl 62208, mdl 62211, and mdl 62873 are three semisynthetic amide derivatives of teicoplanin (mdl 62208 is an amide of teicoplanin aglycone, mdl 62211 is an amide of the teicoplanin a2 complex, and mdl 62873 is the corresponding derivative of peak a2-2 of the complex). the three semisynthetic glycopeptides were evaluated for in vitro antibacterial activity in comparison with the parent drug (teicoplanin) and vancomycin. a variety of gram-positive bacteria of clinical origin, whose species were c ... | 1992 | 1534977 |
| jenseniin g, a heat-stable bacteriocin produced by propionibacterium jensenii p126. | the genus propionibacterium includes cutaneous species typically found on human skin and the dairy or classical species (propionibacterium freudenreichii, p. jensenii, p. thoenii, and p. acidipropionici) used industrially for the production of swiss cheese and propionic acid. grinstead (1989, m.s. thesis, iowa state university, ames) has previously observed that some dairy propionibacteria inhibit other species in the classical grouping. we further investigated the inhibitor(s) produced by p. je ... | 1992 | 1539976 |
| antimicrobial activity of sphingosines. | the antimicrobial activity of stratum corneum lipids was examined by screening in vitro various representative phospholipids and sphingolipids. of mixed galacto-cerebrosides; phosphatidic acid; phosphatidic acid-monomethylester-dioleoyl; phosphatidylethanolamine; phosphatidylethanolamine-beta-oleoyl-gamma-palmitoyl; phosphatidylcholine; d-sphingosine; d,l-sphinganine; 4-d-hydroxysphinganine; oleoyl-sphingosine; n,n-dimethylsphingosine; and stearylamine, only the sphingosines and, to a lesser ext ... | 1992 | 1545135 |
| bacteriologic and endotoxin analysis of salvaged blood used in autologous transfusions during cardiac operations. | autologous blood transfusion is a common method of reducing the need for heterologous blood transfusion during cardiac operations. recently we investigated an outbreak of severe, nonsurgical postoperative bleeding among patients undergoing heart operations and receiving intraoperative transfusion of blood from a cell conservation device (cell saver system, haemonetics corp., braintree, mass.). as a result of this investigation, we conducted a prospective study to determine if bacterial or endoto ... | 1992 | 1545559 |
| antimicrobial susceptibility of anaerobic bacteria in auckland 1987-90. | the antimicrobial susceptibility of 292 clinical isolates of anaerobic bacteria was determined by a standard agar dilution method. metronidazole was the most active agent with only one bacteroides fragilis, two anaerobic cocci, and propionibacterium acnes being resistant. for b fragilis itself and other members of the b fragilis group: 35/35 (100%) and 43/44 (98%) respectively, were susceptible to amoxycillin-clavulanic acid; 47/47 (100%) and 55/56 (98%) respectively, were susceptible to cefoxit ... | 1992 | 1549266 |
| propionibacterium acnes-enhanced lens-induced granulomatous uveitis in the rat. | propionibacterium acnes (corynebacterium parvum) is being implicated more frequently as a cause of intraocular inflammation following cataract surgery. in addition to its role as an infectious agent, p. acnes also may possess adjuvant-like or adjuvant-enhancing properties. the presence of this organism in an eye with residual lens material after extracapsular cataract surgery could augment inflammation resulting from a phacoantigenic (phacoanaphylactic) response. we have modified an established ... | 1992 | 1559776 |
| separation of soluble amoebicidal and tumoricidal activity of activated macrophages. | macrophage-conditioned medium (m phi cm) prepared from mouse peritoneal macrophages activated in vivo with bacillus calmette-guérin (bcg) or propionibacterium acnes and triggered with lipopolysaccharide in vitro contained tumoricidal and amoebicidal activity. the murine fibroblast cell line l929 was used as the indicator of tumoricidal activity and naegleria fowleri amoeba was used to detect amoebicidal activity in m phi cm. the protease inhibitor, soybean trypsin inhibitor, decreased tumoricida ... | 1992 | 1560419 |
| propionibacterium acnes prosthetic valve endocarditis: a case of severe aortic insufficiency. | propionibacterium acnes rarely causes systemic disease. few cases of p. acnes endocarditis have been reported. this report describes a 63-year-old man who presented with severe congestive heart failure. he had prosthetic valve endocarditis which resulted in severe acute aortic insufficiency. during surgery he was found to have complete disruption of the aorta and left ventricle with a false aneurysm encompassing the circumference of the aortic annulus. cultures of the valve grew p. acnes. thus, ... | 1992 | 1563134 |
| gamma interferon mediates propionibacterium acnes-induced hypersensitivity to lipopolysaccharide in mice. | pretreatment of lipopolysaccharide (lps)-responder c57bl/10scsn mice with killed propionibacterium acnes enhanced tumor necrosis factor alpha (tnf-alpha) production and lethality in response to a subsequent challenge with lps. sensitization to lps increased with time of pretreatment and reached its maximum after 7 days. sensitization was paralleled by gamma interferon (ifn-gamma) production that was detectable from day 3 onward. in contrast, a similar p. acnes pretreatment of lps-nonresponder c5 ... | 1992 | 1563791 |
| [release of interleukin-6 by alveolar macrophages in patients with sarcoidosis]. | the supernatants from cultures of alveolar macrophages from 12 patients with sarcoidosis and 7 control subjects were assayed for interleukin-6 (il-6) using an elisa system. il-6 was detectable without a stimulant in supernatants from all subjects with sarcoidosis and controls. however, the supernatants from 4 of 12 untreated patients with sarcoidosis contained significantly greater amounts of il-6. when macrophages were stimulated by propionibacterium acnes (p. acnes), the mean level of il-6 in ... | 1992 | 1569718 |
| risk of bacteremia induced by transesophageal echocardiography: analysis of 100 consecutive procedures. | the incidence of bacteremia induced by transesophageal echocardiography (tee) and, consequently, the need for an antibiotic prophylaxis before tee is still controversial. therefore, we studied the incidence of bacteremia associated with tee prospectively in 100 consecutive patients without clinical or laboratory signs of bacterial infection. blood samples were drawn immediately before and at 0, 5, and 15 minutes after tee. in addition, swabs were taken from the pharyngeal region before tee and f ... | 1992 | 1571172 |
| biofilms on indwelling vascular catheters. | some bacteria have a natural tendency to adhere to available surfaces and to form biofilms. biofilms have been demonstrated on right heart flow-directed catheters, endocardial pacemaker leads, urinary catheters, and other medical devices. in this study, we examined arterial and central venous catheters that had been in place in icu patients between 1 and 14 days for the presence of bacterial biofilms by scanning electron microscopy, transmission electron microscopy, and a special scraping/sonica ... | 1992 | 1572192 |
| propionibacterium acnes keratitis. | | 1992 | 1575243 |
| stimulation of granulopoiesis in pregnant swine and their offspring by propionibacterium avidum kp-40. | functional parameters of granulopoiesis were measured in gilts, in pregnant sows and in their offspring. groups of dams and piglets were injected with a potent immunomodulator--killed lyophilized propionibacterium avidum kp-40 (pa). administration of pa (0.1 mg/kg body wt for sows and 0.2 mg/kg body wt for piglets) resulted in significant stimulation of all measured parameters of granulopoiesis as well as in a faster gain of body weight. pa stimulation of sows prior to farrowing had no measurabl ... | 1992 | 1576517 |
| case records of the massachusetts general hospital. weekly clinicopathological exercises. case 23-1992. a 55-year-old man with recurrent pericardial and pleural effusions after aortic-valve replacement. | | 1992 | 1579139 |
| induction of murine lymphokine-activated killer-like cells by corynebacterium parvum (c. parvum) in vitro: lysis of tumor cells and macrophages by c. parvum-induced killer cells. | in vitro culture of murine spleen cells with corynebacterium parvum (c. parvum) was found to induce lymphokine-activated killer (lak)-like cells capable of killing both natural killer (nk)-sensitive and nk-resistant tumor cells as well as syngeneic macrophages (m phi). the induction of lak-like activity by c. parvum was significantly inhibited by anti-interleukin-2 (il-2) or anti-interferon (ifn) alpha, beta antibody (ab), and it was further inhibited by the combination of two abs, suggesting th ... | 1992 | 1580562 |
| influence of corynebacterium parvum-per on disease progression in the nzb/w model of systemic lupus erythematosus. | murine models of systemic lupus erythematosus (sle) exhibit some, but not all, of the characteristics of human disease. disease progression in the animal models is regulated by autoantibodies, genetics and inflammatory processes. in the present study, the influence of the pyridine extract residue of corynebacterium parvum type i (cp-per) on disease progression in the nzb/w model of sle was investigated. cp-per is known to activate the reticuloendothelial (re) system of mice and can alter a numbe ... | 1992 | 1582732 |
| generation of cytotoxic immune responses against a rat glioma by in vivo priming and secondary in vitro stimulation with tumor cells. | cytotoxic t lymphocyte (ctl) responses to most antigens are generated by in vivo priming and secondary stimulation with antigen in vitro. the present studies were designed to determine whether that strategy could be used to stimulate development of ctl against brain tumors. rats were primed with one of two tumors, rt2, an astrocytoma, or 9l, a gliosarcoma, and corynebacterium parvum. spleen cells from primed rats were stimulated with tumor cells and interleukin-2 in vitro to generate ctl. ctl ge ... | 1992 | 1584347 |
| propionibacterium acnes endophthalmitis after intracapsular cataract extraction. | the authors report a case of propionibacterium acnes endophthalmitis after intracapsular cataract extraction with implantation of an anterior chamber intraocular lens. the patient's chronic inflammation persisted for 5 years after cataract surgery despite treatment with pars plana vitrectomy, intraocular lens removal, topical and oral steroids, and topical fortified antibiotics. fluctuations in the inflammation were paralleled by changes in the size and appearance of a white plaque on the poster ... | 1992 | 1584564 |
| corynebacterium parvum can reverse the depression of macrophage hydrogen peroxide production caused by erythrocyte phagocytosis. | our previous studies have shown that the phagocytosis of igg-coated erythrocytes (eigg) in vivo increases the mortality rate with bacterial infection, and eigg phagocytosis in vitro depresses phorbol myristate acetate (pma)-triggered h2o2 production. the present study was undertaken to determine if the depression of h2o2 production caused by eigg phagocytosis could be reversed by exposing macrophages to priming agents. macrophages exposed to 100 micrograms/ml of c. parvum, it's pyridine-soluble ... | 1992 | 1587558 |
| high serum il-6 level reflects susceptible status of the host to endotoxin and il-1/tumor necrosis factor. | patients with high level of serum endotoxin did not necessarily develop into lethal shock, whereas some patients died of septic shock even when their serum endotoxin levels were low. these results indicate that limiting factor which determines the host to be endotoxin shock principally depends on the host susceptibility to endotoxin instead of serum endotoxin level. to understand this susceptible status of the host to endotoxin, we used propionibacterium acnes primed mouse endotoxin shock model. ... | 1992 | 1588048 |
| susceptibilities of anaerobic bacteria isolated from animals with ovine foot rot to 28 antimicrobial agents. | the agar dilution method was used to determine the inhibitory activities of 28 antimicrobial agents against 35 strains of the genus peptostreptococcus, 4 strains of the species peptococcus niger, 20 strains of the species megasphaera elsdenii, 7 strains from the species acidaminococcus fermentans, 8 strains of the genus clostridium, 11 strains of the genus eubacterium, and 1 strain of the species propionibacterium acidipropionici, all of which were isolated from 125 clinical cases of ovine foot ... | 1992 | 1590689 |
| [transformation of [5'-3h]riboflavin into 5,6-dimethylbenzimidazole]. | the 5,6-dimethylbenzimidazole unit of vitamin b12 is formed from riboflavin via fmn in aerobic and some aerotolerant bacteria. thereby c-1' of the ribityl side chain gets c-2 of 5,6-dimethylbenzimidazole. experiments with homogenates of propionibacterium shermanii on the fate of c-atoms 2' to 5' of the ribityl side chain of riboflavin in this transformation are reported. it was found that [5'-3h]riboflavin leads to radioactive sugar phosphates. these were isolated, dephosphorylated, and separate ... | 1992 | 1590885 |
| [splenic abscess: therapeutic options]. | pyogenic splenic abscess is a rare condition that tends to occur in patients with underlying often infectious diseases. the sensitivity of ultrasonography and computerized tomography has improve early diagnosis and follow-up. in our hands, splenectomy remains the therapy of choice, but we report the resolution of two uncomplicated splenic abscesses with antibiotics alone. | 1992 | 1592631 |
| susceptibility of anaerobic bacteria to tosufloxacin. | the in vitro activity of tosufloxacin against anaerobic cocci, propionibacterium acnes, clostridium perfringens, clostridium difficile, bacteroides fragilis, bacteroides spp. and fusobacteria was determined by the agar dilution method. this activity was compared with that of ciprofloxacin, piperacillin, cefoxitin, imipenem, clindamycin, metronidazole and chloramphenicol. tosufloxacin, imipenem, clindamycin, metronidazole and chloramphenicol were the most active agents tested. tosufloxacin has an ... | 1992 | 1597207 |
| validity of delayed-type hypersensitivity and graft-versus-host reaction in testing of immunomodulators. | assessment of cell-mediated immunity (cmi) is an integral part of preclinical studies of pharmaceuticals and xenobiotics. even if several tests to determine cmi are available, their interpretation is fraught with uncertainty whether identical results can be expected for each of these particular tests after the challenge with different immunomodulatory substances. this dilemma has been addressed by investigating the changes in two basic tests of cmi in vivo, i.e. delayed-type hypersensitivity (dt ... | 1992 | 1597252 |
| alternative antimicrobial agents to contemporary treatment of infections caused by corynebacterium parvum (propionibacterium acnes) | | 1992 | 1607339 |
| the effect of zinc and erythromycin on the growth of erythromycin-resistant and erythromycin-sensitive isolates of propionibacterium acnes: an in-vitro study. | the effect of zinc and erythromycin on cultures inoculated with mixtures of different ratios of erythromycin sensitive (es) and resistant (er) propionibacterium acnes cells was studied in vitro. propionibacterium acnes es outgrew p. acnes er in the absence of erythromycin and zinc. at low levels of erythromycin es outgrew er, whilst the addition of 600 pg/ml zinc further reduced the growth of er compared to es. growth of er and es were similar at levels of erythromycin near the minimum inhibitor ... | 1992 | 1610692 |
| effects of intravesical corynebacterium parvum on recurrences of superficial tumors of the urinary bladder. | we studied 96 patients with superficial tumors of the urinary bladder treated by transurethral resection in order to investigate the value of intravesical corynebacterium parvum (cp) to prevent recurrences. in 52 cases, two vials (2 ml, 4 mg cp) diluted in 60 ml buffer saline were intravesically administered weekly 12 times and then monthly for a period of 2 years. all patients were studied in a 3 year follow-up by cytology, histology and endoscopy. recurrences were observed in 21.1% of cases in ... | 1992 | 1623214 |
| combined influence of magnesium concentration and polymerase chain reaction specificity enhancers. | | 1992 | 1624113 |
| protective effects of (2e)-3-[5-(2,3-dimethoxy-6-methyl-1,4- benzoquinoyl)]-2-nonyl-2-propenoic acid on endotoxin-mediated hepatitis in mice. | e3330 [(2e)-3-[5-(2,3-dimethoxy-6-methyl-1,4-benzoquinoyl)]-2-nonyl-2- propenoic acid] is a newly synthesized hepatoprotective quinone derivative. we examined the protective effects and possible mechanism of action of e3330 in three different endotoxin (lipopolysaccharide)-induced murine hepatitis models, in which tumor necrosis factor is suggested to play a critical role in the pathogenesis. one of these models was induced by i.v. injection of lipopolysaccharide in combination with d-galactosam ... | 1992 | 1625194 |
| some characteristics of blood shed into the solcotrans postoperative orthopaedic drainage/reinfusion system. | to assess the suitability of blood shed into the solcotrans orthopaedic autotransfusion system as a source of autologous blood for transfusion. | 1992 | 1630397 |
| a zymographic assay for detection of hyaluronidase activity on polyacrylamide gels and its application to enzymatic activity found in bacteria. | a zymographic assay for the determination of hyaluronidase activity in cell-free extracts on native polyacrylamide gels has been developed. in this assay an agarose replica of the polyacrylamide gel which contains hyaluronic acid and bovine serum albumin (bsa) was used. after an incubation at 37 degrees c to allow transfer and development of enzymatic activity, the hyaluronic acid and bsa were precipitated in the agarose gel with 2 m acetic acid. areas of enzymatic activity appeared as clear zon ... | 1992 | 1632506 |
| iris nodule and intralenticular abscess associated with propionibacterium acnes endophthalmitis. | | 1992 | 1637275 |
| immunologically mediated fatigue: a murine model. | chronic fatigue syndrome (cfs) is an idiopathic disorder in which the chief symptoms is profound fatigue. to explore the relationship between immune stimulation and fatigue, we developed a murine model for quantifying fatigue: reduction in voluntary running and delayed initiation of grooming after swimming. inoculation of female balb/c mice with corynebacterium parvum antigen or the relatively avirulent me49 strain of toxoplasma gondii induced fatigue: baseline running reduced to less than 50 an ... | 1992 | 1643746 |
| effects of corticosterone and microgravity on inflammatory cell production of superoxide. | in this investigation we studied the effects of corticosterone and microgravity on propionibacterium acnes-induced inflammatory cells ability to produce superoxide (o2-). we found in vitro and in vivo exposure of murine peritoneal inflammatory cells to corticosterone did not inhibit the o2- response. we also found that in microgravity p. acnes-induced inflammatory cells were capable of producing four times as much o2- as at 1g. therefore, neither corticosterone nor microgravity experienced durin ... | 1991 | 1647434 |
| comparative studies on a superoxide dismutase exhibiting enzymatic activity with iron and manganese as active cofactor. | the sod of propionibacterium freudenreichii, ssp. shermanii belongs to a new group of sod's capable of retaining activity with either fe or mn as active metal cofactor. both enzymes exhibit identical secondary structure and immunological determinants. hydrogen peroxide irreversibly inhibits both enzymes. the protein moiety of the fe- and mn-sod could be digested with trypsin to a single active fragment. | 1991 | 1649091 |
| activity of mersacidin, a novel peptide, compared with that of vancomycin, teicoplanin, and daptomycin. | mersacidin, a new peptide antibiotic, was four- to eightfold less active (mic for 90% of isolates, 8 micrograms/ml) than vancomycin, teicoplanin, or daptomycin against staphylococcus aureus. coagulase-negative staphylococci were inhibited by 8 micrograms/ml, and the mics of mersacidin for hemolytic streptococci and streptococcus pneumoniae were 4 to 8 micrograms/ml. the mersacidin mics for anaerobic organisms were as follows: clostridium perfringens, 4 micrograms/ml; propionibacterium acnes, 8 m ... | 1991 | 1649577 |
| near-uv-induced radicals in propionibacterium acnes, studied by electron spin resonance spectrometry at 77 k. | suspensions of propionibacterium acnes were uv irradiated and the induced radicals were measured at 77 k by electron spin resonance (esr) spectrometry. two types of radical were formed during irradiation and stabilized in the frozen suspensions. the relative yield of each radical was studied as a function of irradiation wavelength. the first radical, which was a singlet with a peak-to-peak width of 20 g, was insensitive to the deoxygenation of the samples and to the exchange of solvent water by ... | 1991 | 1650821 |
| cloning, sequencing, and expression of pyrophosphate-dependent phosphofructokinase from propionibacterium freudenreichii. | pyrophosphate-dependent 6-phosphofructo-1-kinase (ppi-pfk) from propionibacterium freudenreichii is a non-allosteric enzyme with properties dissimilar to those of other described phosphofructokinases. the enzyme was cloned into pbluescript, sequenced, and expressed in escherichia coli at levels 15 times higher than those observed in propionibacterium. the gene consists of 1215 bases which code for a protein of 404 amino acids and a mass of 43,243 daltons. high g + c in the codon usage (66%) of t ... | 1991 | 1653240 |
| changes in polyphosphate composition and localization in propionibacterium acnes after near-ultraviolet irradiation. | electron microscopy showed that electron-dense granules accumulated in propionibacterium acnes in larger amounts when the bacteria were grown on a phosphate-rich medium. x-ray microanalysis demonstrated that the granules contained mostly phosphorus and potassium, indicating that the cells contained polyphosphate granules. when cells were grown on a complex bacto-agar medium, the amount and the size of the polyphosphate granules were reduced. polyphosphate was also detected with 31p nuclear magne ... | 1991 | 1655185 |
| the appearance of t cells bearing self-reactive t cell receptor in the livers of mice injected with bacteria. | we demonstrated in the present study that with bacterial stimulation, an increased number of alpha/beta t cells proliferated in the liver of mice and that even t cells bearing self-reactive t cell receptor (tcr) (or forbidden t cell clones), as estimated by anti-v beta monoclonal antibodies in conjunction with immunofluorescence tests, appeared in the liver and, to some extent, in the periphery. the majority (greater than 80%) of forbidden clones induced had double-negative cd4-8-phenotype. in a ... | 1991 | 1677392 |
| mechanism of gram variability in select bacteria. | gram stains were performed on strains of actinomyces bovis, actinomyces viscosus, arthrobacter globiformis, bacillus brevis, butyrivibrio fibrisolvens, clostridium tetani, clostridium thermosaccharolyticum, corynebacterium parvum, mycobacterium phlei, and propionibacterium acnes, using a modified gram regimen that allowed the staining process to be observed by electron microscopy (j. a. davies, g. k. anderson, t. j. beveridge, and h. c. clark, j. bacteriol. 156:837-845, 1983). furthermore, since ... | 1990 | 1689718 |
| tetracycline and 13-cis-retinoic acid inhibit production and activity of granulocyte activating factor (gaf) from propionibacterium acnes. | the aim of this study was to evaluate different treatment schedules on release or activity of a granulocyte activating factor (gaf) from propionibacterium acnes. incubation of p. acnes in physiological saline (30 min, 37 degrees c) resulted in release of a soluble factor that elicited considerable chemiluminescence response and chemotactic stimulus on human granulocytes. pretreatment of the microorganisms with subinhibitory concentrations of tetracycline or incubation of granulocytes with 13-cis ... | 1990 | 1698375 |
| corynebacterium parvum (propionibacterium acnes): an inducer of tumor necrosis factor-alpha in human peripheral blood mononuclear cells and monocytes in vitro. | the present study investigates the potential capacity of the immunostimulant corynebacterium parvum (c.p.) to induce tumor necrosis factor-alpha (tnf-alpha) in human peripheral blood mononuclear cells (pbmc) and blood monocytes (bmo) in vitro. both at the mrna and protein level, stimulation of pbmc and bmo upon c.p. induces tnf-alpha. compared to the hitherto used tnf-alpha inducers in vitro such as sendai virus, phytohemagglutinin or lipopolysaccharide the c.p. stimulus displayed a threefold st ... | 1990 | 1698632 |
| antimutagenicity of propionic acid bacteria. | the antimutagenic effect of dialysed cell extracts of 4 strains of propionic acid bacteria was examined against the mutagenicity of sodium azide in the ta1535 tester strain of salmonella typhimurium using the ames test. it was noted that dialysates of 2 strains of propionibacterium shermanii, p. pentosaceum and p. acnes, significantly reduced sodium azide-induced revertants. the dialysate of propionic acid cocci did not show an antimutagenic effect. the inhibitory activity was enhanced if the mu ... | 1991 | 1720873 |
| inhibition of nk cell generation by corynebacterium parvum. | treatment of mice with corynebacterium parvum (cp) resulted in a substantial decrease of splenic nk activity associated with a reduced number of lgl. cp also inhibited in vitro augmentation of nk cytotoxicity by ifn or il-2 as well as generation of lak activity. localization experiments by using radiolabelled lgl indicated that the lower number of lgl in the spleen was not attributable to a cp-induced alteration of lgl homing. finally cp was found to affect the ability of bone marrow cells to re ... | 1991 | 1723083 |
| use of immunomodulators as an aid to clinical management of feline leukemia virus-infected cats. | | 1991 | 1724773 |
| [comparison of the results of the treatment of patients with sspe using various immunomodulating preparations]. | the authors analysed the results of controlled treatment by three methods of patients in the 1st or 2nd phase of sspe in a randomized group. the groups received: i. propionibacterium granulosum kp-45 (interferon inducer) + isoprinosine, ii--tfx (thymus extract) + isoprinosine, iii--only isoprinosine. in all groups the treatment was continued during 6 months. the analysis of the clinical results of these methods failed to demonstrate a statistically significant superiority of any of these methods ... | 1991 | 1725554 |
| the in-vitro antimicrobial effects of azelaic acid upon propionibacterium acnes strain p37. | the in-vitro antimicrobial activity of azelaic acid a new topical acne treatment, upon propionibacterium acnes strain p37 was studied. in phosphate buffer at ph 6.0 500 mm azelaic acid had bactericidal activity whilst the addition of nutrients reduced susceptibility. bactericidal activity was greatly enhanced by reducing the ph to 5.6. in a simple defined medium growth was inhibited by 100 microm azelaic acid. the accumulation of 14c azelaic acid was ph and temperature dependent with maximum upt ... | 1991 | 1726169 |
| endocarditis after acupuncture and injection--treatment by a natural healer. | | 1992 | 1727196 |
| changes in the microbial flora of airline headset devices after their use. | the bacterial flora of 20 headset devices were evaluated before and after they were worn for 1 hour. bacteria were recovered from all headsets, and their number increased from a mean (+/- standard deviation) of 60 +/- 5 organisms per device to 650 +/- 51 organisms per device (p less than .001). the predominant organisms recovered were staphylococcus spp, streptococcus spp, propionibacterium spp, and peptostreptococcus spp. this study demonstrates the presence of potential pathogens in headset de ... | 1992 | 1731163 |
| activation of mononuclear immune cells in response to staphylococcal lipoteichoic acid. | the goal of the present study was to evaluate the influence of staphylococcal lipoteichoic acid (lta) on the activation of mononuclear immune cells. a murine tumor necrosis-like factor (tnf-like) was induced in the sera of cd-1 mice which had been primed with heat/formalin-inactivated propionibacterium avidum kp-40 and subsequently exposed to lta extracted from staphylococcus saprophyticus strain s 1. monoclonal antibody against murine tnf (anti-tnf) significantly inhibited the cytostatic activi ... | 1991 | 1741920 |
| cutaneous immunopathology of androgenetic alopecia. | male pattern baldness is assumed to result from a combination of normal serum concentrations of androgen and an appropriate genetic background. to study whether inflammation contributes to the development of androgenetic alopecia, direct immunofluorescence and dermatopathologic studies were performed on biopsy specimens from bald scalp of patients, with specimens from uninvolved scalp of these patients or from scalp of volunteers who were not bald serving as controls. granular deposits of immuno ... | 1991 | 1744007 |
| inhibition of immune reactions in vivo by liposome associated transforming growth factor (tgf) type beta 1. | in view of its potent inhibitory capacity on immune cells in culture, we wished to determine the ability of transforming growth factor (tgf) beta 1 to down-regulate immune responses in vivo. preliminary experiments suggested that, at the doses used, systemic injection of soluble tgf beta 1 could not affect bacterial-induced spleen enlargement in mice. therefore, we sought to utilize a physiochemical property of this molecule, namely its high pi, to determine possible association between the liga ... | 1991 | 1747960 |
| prophylactic and therapeutic application of propionibacterium avidum kp-40 in swine and calves with acute enzootic bronchopneumonia. | the usefulness of the prophylactic or therapeutic application of propionibacterium avidum kp-40, a potent stimulator of the monocyte-macrophage-system, was demonstrated in piglets and calves. after a 3-month-period of observation pa-treated piglets showed a significantly improved development (decreased number of infections, gain of body weight). in piglets and calves the therapeutic use of pa together with oxytetracycline proved to be superior in the treatment of acute endemic enzootic bronchopn ... | 1991 | 1752209 |
| [intrascrotal and seminal vesicular granuloma probably induced by propionibacterium acnes]. | a case of right intrascrotal and seminal vesicular granuloma probably induced by propionibacterium acnes is reported. a 62-year-old man was admitted to our department because of low grade fever and the right intrascrotal and retrovesical masses without tenderness. ultrasonography computed tomography, magnetic resonance imaging and vesiculography suggested a neoplasm. however, leukocytosis and high erythrocyte sedimentation rate (esr) and c-reactive protein level (crp) suggested inflammatory dise ... | 1991 | 1755428 |
| [biochemical activity of microbial populations of the gastrointestinal tract and the effect of antibacterial drugs]. | | 1991 | 1755712 |
| efficacy of cloxacillin prophylaxis in craniotomy: a one year follow-up study. | a previous prospective double-blind placebo-controlled study showed that cloxacillin prophylaxis significantly reduces the rate of infection after craniotomy. the purpose of the present follow-up study was to find out whether the data on routine cloxacillin prophylaxis would confirm the decreased infection rate after craniotomy. during this 1-year study, 8 infections occurred after 201 operations (4.0%) in 175 patients. no prophylaxis was given during 17 operations in 15 patients; 4 infections o ... | 1991 | 1767259 |
| propionibacterium acnes endophthalmitis. | | 1991 | 1768654 |
| posterior lens capsule abscess due to propionibacterium acnes and staphylococcus epidermidis following extracapsular cataract extraction. | a case of posterior lens capsular abscess occurring many months after an extracapsular cataract extraction is presented. this was caused by a mixed infection involving propionibacterium acnes and staphylococcus epidermidis. the significance of staph epidermidis after such a long postoperative period is uncertain, but the case shows features typical of secondary endophthalmitis due to p acnes, including a long delay in onset and a grumbling course not brought under control by medical treatment. i ... | 1991 | 1768656 |
| effect of gomisin a in the prevention of acute hepatic failure induction. | nearly all rats develop massive hepatic cell necrosis and die upon intravenous administration of heat-killed propionibacterium acnes followed by a small amount of gram-negative lipopolysaccharide 7 days later. however, when such an experimental liver disorder is induced in rats raised for 4 or more weeks on food containing 0.06% of gomisin a extracted and purified from schizandra chinensis, the survival rate rises, histological changes of the liver improve remarkably, and splenocyte reactivity t ... | 1991 | 1775571 |
| [activation of the resident microbial flora as a possibility for the improvement of humoral antibody potentials]. | the effect of a parenteral application of an adjuvant (propionibacterium acnes) and an adjuvant/antigen combination (staphylococcus aureus cowan i/al(oh)3, pseudomonas aeruginosa/al(oh)3 respectively, was tested with regard to the improvement of antibacterial resistance. parameter was the humoral antibody production (igg) of rabbits against six facultative pathogen bacterial species (st. aureus, sc. faecium, bac. cereus, p. multocida, e. coli, ps. aeruginosa) and against sheep rod blood cell mem ... | 1991 | 1786043 |
| latex agglutination test: an adjunct to the laboratory diagnosis of pyogenic bacterial meningitis. | gram stain, culture and latex agglutination test (lat) of cerebrospinal fluid were performed in 50 patients clinically diagnosed as suffering from pyogenic bacterial meningitis. using all the three techniques, an aetiological diagnosis was made in 27 (54%). neisseria meningitidis, streptococcus pneumoniae and h. influenzae were the infecting organisms in 21 cases (44%). there were 12 additional cases in which lat was the only clue to the diagnosis as compared to conventional techniques. propioni ... | 1991 | 1800334 |
| comparative in vitro activity of cefpodoxime against anaerobes other than bacteroides fragilis. | to assess the in vitro activity of cefpodoxime against anaerobic respiratory tract and oropharyngeal pathogens 77 strains belonging to 18 gram-negative and 7 gram-positive species were studied by means of agar dilution tests. for comparison cefuroxime, amoxicillin, amoxicillin + clavulanic acid and clindamycin were also tested. cefpodoxime was found to be active at concentrations of less than or equal to 0.125 mg/l against prevotella oralis, prevotella buccalis, prevotella bivia, porphyromonas a ... | 1991 | 1800380 |
| [counts of selected strict and facultatively anaerobic microorganisms in the crop and appendix of chickens and their adhesion characteristics]. | the counts of strictly anaerobic amylolytic and lactate-utilizing bacteria, streptococci, lactobacilli, escherichia coli and lactoso-negative bacteria were followed in chicks at the age of three to seven weeks. age dependences of the counts in the given groups were investigated. an increase in the counts of amylolytic bacteria was observed in the caecum contents in the seventh week (4.63 +/- 0.322), and on the other hand a decrease in their counts in the caecum wall in the seventh week (3.30 +/- ... | 1991 | 1807031 |
| hepatoprotective effects of 1-[(2-thiazolin-2-yl)-amino]acetyl-4-(1,3-dithiol-2-ylidene)-2,3,4,5- tetrahydro-1h-1-benzazepin-3,5-dione hydrochloride (kf-14363) in various experimental liver injuries. | hepatoprotective effects of kf-14363 were investigated in the following experimental models. kf-14363 inhibited the increase in serum glutamate pyruvate transaminase (gpt) dose-dependently, and a significant inhibition was noted at a dose of 30 mg/kg or more. kf-14363 significantly inhibited the d-galactosamine (d-gal)-induced increase in serum transaminase by oral administration at 250 mg/kg x 1 and 250 mg/kg x 2 doses. the d-gal-induced decrease in total protein levels was inhibited at doses o ... | 1991 | 1812294 |
| correlation between antimicrobial activity and chelating ability of 2-(n,n,n-trialkylammonio)alkyl hydrogen phosphates. | the chelating abilities of phosphobetaines [2-(n,n,n-trialkylammonio)alkyl hydrogen phosphates; 1] for divalent cations (e.g., calcium ion, zinc ion, copper ion, and cadmium ion) were investigated to elucidate the correlation between the antimicrobial activity and the chelating ability. the maximal chelating ability was obtained with the compound having a dimethylene bridge as an intercharge distance between the phosphate and quaternary ammonium group; in contrast, the minimum was obtained with ... | 1991 | 1815056 |
| [antimutagenicity of propionic acid bacteria]. | the antimutagenicity of the cell extracts of propionibacterium shermanii vkm-103, p. pentosaceum ccm 1859 and p. acnes ccm 3322 against mutagenicity of sodium azide and n-methyl-n'-nitro-n-nitrosoguanidine was demonstrated for the first time. the extracts of propionic acid cocci didn't show such effect. the antimutagenic factor acts as a desmutagen, has polypeptide nature and evidently is an enzyme (enzymes). the inhibitory effect of the extract is due to the presence of more than one protein fa ... | 1991 | 1819041 |
| isolation and classification of anaerobic bacteria from pulp cavities of nonvital teeth in man. | the anaerobic microflora of infected pulp cavities and chronic periapical abscesses was studied. a total of 19 infected nonvital teeth were subjected to this study. the coronal surface was swabbed with 70% ethanol to remove debris and to disinfect. material in root canal chamber was obtained by sterilized paper points and suspended in reduced transport fluid. the samples were dispersed, diluted, and inoculated on blood agar plates. isolates were identified by colony characteristics and cellular ... | 1991 | 1819449 |
| acne vulgaris. pathogenesis and treatment. | acne vulgaris is a multifactorial disease involving abnormalities in follicular keratinization, sebum production, proliferation of propionibacterium acnes, and inflammation. treatment is directed toward reversing these underlying pathogenic factors. therapeutic options include topical comedolytics, topical and systemic antibiotics, hormonal manipulations, and oral retinoids. | 1991 | 1831256 |
| immunomodulation in an apparently non-immunogenic murine tumor. | madison lung carcinoma (m109), a murine tumor of spontaneous origin, appears to be non-immunogenic, according to 2 commonly employed tests for tumor immunogenicity. however, c.parvum-induced immunopotentiation during the growth of m109 tumor results in post-excision anti-tumor immunity to m109 tumor implants. the c.parvum-potentiated post-excision immunity to m109 is tumor-specific and t-cell-dependent. t cells from mice whose progressive m109 tumors have been excised are capable, on passive tra ... | 1991 | 1833344 |
| effects of subminimal inhibitory concentrations of erythromycin, tetracycline, clindamycin, and minocycline on the neutrophil chemotactic factor production in propionibacterium acnes biotypes 1-5. | biotypes 1-5 propionibacterium acnes (p. acnes) strains were grown in the presence of 1/10 minimal inhibitory concentrations (sub-mic) of erythromycin (em), tetracycline (tc), clindamycin (cldm), or minocycline (mino) and their culture filtrates were assayed for human neutrophil chemotactic activity using boyden chamber methods. the addition of sub-mic of mino to the medium strongly suppressed the neutrophil chemotactic activity of the culture filtrates of p. acnes strains of all biotypes. in co ... | 1991 | 1834712 |
| acne: current concepts of pathogenesis and approach to rational treatment. | acne is a skin disorder of the sebaceous follicles that commonly occurs in adolescence and young adulthood. the pathogenesis involves abnormal follicular hyperkeratosis and obstruction of the follicle, stimulation of sebaceous gland secretion by androgens, and proliferation of propionibacterium acnes, which promotes inflammation. treatment regimens should be designed based upon an understanding of the multifactorial basis of pathogenesis. both topical and systemic agents may be employed to norma ... | 1991 | 1835004 |
| the effects of adjuvants on immune responses in cattle injected with a brucella abortus soluble antigen. | five different adjuvants were examined for potentiation of humoral and cell-mediated immune (cmi) responses in cattle to a brucella abortus soluble antigen (basa). two separate experiments were performed involving a total of 64 steers, divided among six groups (experiment 1) and 9 groups (experiment 2). the adjuvants used were: muramyl dipeptide, freund's incomplete adjuvant, dimethyl-dioctadecyl ammonium bromide (dda), bordetella pertussis and propionibacterium acnes. in each experiment, three ... | 1991 | 1835213 |
| seborrheic skin and acne vulgaris as protective factors against the development of basal cell epithelioma. | this study was conducted in order to evaluate a possible protective role of seborrheic complexion and a history of acne on the development of basal cell epithelioma (bce). for this purpose, 77 patients with this tumor were examined and asked to fill out a questionnaire. the questionnaire included demographic data and questions about skin type, eye and hair colors, sun exposure habits and a past history of acne. the nature, number and location of tumors, the texture of skin and acne scars were no ... | 1991 | 1835940 |
| effects of subminimal inhibitory concentrations of minocycline on neutrophil chemotactic factor production in comedonal bacteria, neutrophil phagocytosis and oxygen metabolism. | comedonal bacteria, propionibacterium acnes, p. granulosum and coagulase-negative staphylococci (cns) seem to play an important initiating role in the inflammatory process by producing neutrophil chemotactic factors. the attracted neutrophils, after phagocytosis, release inflammatory factors such as reactive oxygen species (ros). we investigated the effects of minocycline at subminimal inhibitory concentrations (sub-mic), i.e. one-tenth mic, on the production of human neutrophil chemotactic fact ... | 1991 | 1838472 |
| pathogenesis and pathogenesis related treatment of acne. | | 1991 | 1838558 |
| clinical and bacteriologic evaluation of opc-7251 in patients with acne: a double-blind group comparison study versus cream base. | twenty-eight patients with acne were assigned to 4 weeks of treatment with opc-7251 (a new fluoroquinolone derivative) 1% cream or the cream base in a double-blind manner to evaluate the antibacterial effect of the drug on resident bacteria in the hair follicles and to evaluate clinical response. propionibacterium acnes was isolated from 21 of the 28 acne patients. when the number of p. acnes was compared before and after treatment, the posttreatment p. acnes count in the opc-7251 1% cream group ... | 1991 | 1838749 |
| an open study of teicoplanin in the treatment of gram-positive infections. | teicoplanin, a new glycopeptide antibiotic similar to vancomycin, was evaluated in treating 36 hospitalized patients suffering from various gram-positive infections. the 36 patients received teicoplanin once daily as a mean intravenous injection of 550 mg/day (range 200-800 mg/day). previous antimicrobial therapy was used in 28% of patients. the mean duration of therapy was 7.5 days (range 3-38 days). the overall clinical success rate was 94%. 24/36 patients (66%) had positive microbiology. elim ... | 1991 | 1839742 |
| [immunomodulating properties of acnevac vaccine]. | the influence of acnevac vaccine on immune responses of cba mice was tested. acnevac, the vaccine used in a treatment of patient with acne vulgaris, was produced by a cracow sera and vaccines manufacturer from cultures of propionibacteria-strains. it was shown that acnevac has strong immunomodulatory properties. it strongly stimulates humoral responses, has moderate effect on cell-mediated immune responses and it also activates peritoneal macrophages to release tnf-alpha. | 1991 | 1840429 |
| phylogenetic analysis of some ll-diaminopimelic acid-containing coryneform bacteria from human skin: description of propionibacterium innocuum sp. nov. | a new species, propionibacterium innocuum, is proposed to accommodate strains of coryneform bacteria from human skin with phenotypic characters similar to those of the classical propionibacteria but differing in exhibiting primarily aerobic respiration and possessing a unique cell wall composition in which ll-diaminopimelic acid and arabinose occur together. the partial 16s rrna sequence confirms an affinity with the genus pro-pionibacterium and indicates that the species represents a distinct l ... | 1991 | 1840533 |
| torulopsis candida (candida famata) endophthalmitis simulating propionibacterium acnes syndrome. | four months after undergoing extracapsular cataract extraction with implantation of a posterior chamber intraocular lens, a 74-year-old woman developed granulomatous anterior uveitis. although she initially responded well to corticosteroid therapy, she experienced multiple recurrences on discontinuation of this therapy. slit-lamp examination showed the ocular inflammation to be associated with white cortical material within the lens capsular sac. she underwent removal of the implant as well as t ... | 1991 | 1841584 |
| [culture of anaerobic bacteria and antibiotic sensitivity test in ocular infectious diseases]. | anaerobes were isolated from 43.9% of 116 eyes with infectious diseases and 21.4% of 140 normal conjunctival sacs. the predominant anaerobes were peptococcus (28.6%) in the former and propionibacterium (53.3%) in the latter. in eyes with infection, only anaerobes were isolated from 27, and a mixture of anaerobes and aerobes in 24. the sensitivity of anaerobes (68 strains) to 10 antibiotics differed significantly from that of aerobes (102 strains). most anaerobes are sensitive to chloramphenicol ... | 1991 | 1860409 |
| controlled release of benzoyl peroxide from a porous microsphere polymeric system can reduce topical irritancy. | skin absorption of benzoyl peroxide from a topical lotion containing freely dispersed drug was compared with that from the same lotion in which the drug was entrapped in a controlled-release styrene-divinylbenzene polymer system. in an in vitro diffusion system, statistically significant (p = 0.01) differences were found in the content of benzoyl peroxide in excised human skin and in percutaneous absorption. in vivo, significantly (p = 0.002) less benzoyl peroxide was absorbed through rhesus mon ... | 1991 | 1869643 |
| nosocomial infections of ocular conjunctiva in newborns delivered by cesarian section. | colonization of the ocular conjunctiva in newborns delivered by cesarian section occurs usually within the first day of life. we have studied the flora of the ocular conjunctiva at birth, from 19 newborns delivered by cesarian section, coming from two different maternity hospitals. ocular conjunctiva cultures yielded the main predominant flora in both maternity hospitals considered. the most common genus of this flora are: staphylococcus, corynebacterium and propionibacterium acnes. peptostrepto ... | 1991 | 1870845 |
| [refractory hiccup after intrapleural injection of corynebacterium parvum]. | | 1991 | 1882165 |
| fate of the fellow eye after propionibacterium acnes endophthalmitis. | | 1991 | 1882935 |
| protective effect of (4r)-hexahydro-7,7-dimethyl-6-oxo-1,2,5-dithiazocine-4-carboxylic acid (sa3443), a novel cyclic disulfide, on immunologically induced liver injuries in mice. | the effects of (4r)-hexahydro-7,7-dimethyl-6-oxo-1,2,5-dithiazocine-4- carboxylic acid (sa3443), a novel cyclic disulfide, on new immunological liver injury models were investigated. the first liver injury model included a single injection of rabbit anti-basic liver protein antibody into dba/2 mice. serum transaminase activities showed a dose-dependent increase 42 hr after the antibody treatment. sa3443 significantly inhibited the elevation of serum transaminase activity and the histopathologica ... | 1991 | 1888226 |
| the importance of positive bacterial cultures of specimens obtained during clean orthopaedic operations. | microbiological cultures of specimens of tissue and of fluids from the wound in forty patients who had had consecutive clean, elective orthopaedic operations (excluding total joint replacements) and had not received antibiotics preoperatively were analyzed. of the forty patients, twenty-three (58 per cent) had a positive culture on at least one of the media that were used and seventeen (43 per cent) had negative cultures. of the forty specimens that were obtained from swabbing of the wound, eigh ... | 1991 | 1890121 |
| effect of endogenous nitric oxide on mitochondrial respiration of rat hepatocytes in vitro and in vivo. | nitric oxide, a highly reactive radical, was recently identified as an intermediate of l-arginine metabolism in mammalian cells. we have shown that nitric oxide synthesis is induced in vitro in cultured hepatocytes by supernatants from activated kupffer cells or in vivo by injecting rats with nonviable corynebacterium parvum. in both cases, nitric oxide biosynthesis in hepatocytes was associated with suppression of total protein synthesis. this study attempts to determine the effect of nitric ox ... | 1991 | 1899557 |
| cellular fatty acid composition as an adjunct to the identification of asporogenous, aerobic gram-positive rods. | cellular fatty acid (cfa) compositions of 561 asporogenous, aerobic gram-positive rods were analyzed by gas-liquid chromatography as an adjunct to their identification when grown on blood agar at 35 degrees c. the organisms could be divided into two groups. in the first group (branched-chain type), which included coryneform cdc groups a-3, a-4, and a-5; some strains of b-1 and b-3; "corynebacterium aquaticum"; brevibacterium liquefaciens; rothia dentocariosa; and listeria spp., the rods had siza ... | 1991 | 1899679 |