| serological tests for legionella pneumophila serogroup 1 infections. | the indirect fluorescent antibody test (ifat) using a formolised yolk sac antigen (fysa) has been shown to be a sensitive, specific test for legionellosis and results obtained on the same serum specimens in different laboratories agree closely. the rapid micro-agglutination test (rmat) has the advantage of being semi-automatable and also sensitive and specific. both tests gave negative results with sera from patients with infections due to mycoplasma pneumoniae, chlamydia psittaci, coxiella burn ... | 1983 | 6356710 |
| serologic testing of wild roe deer (capreolus capreolus l.) from the trois fontaines forest region of eastern france. | | 1983 | 6358537 |
| energy conservation in acidophilic bacteria. | | 1983 | 6363899 |
| [comparative value of complement fixation and indirect immunofluorescence reactions for the detection of q fever]. | 1 052 serum samples from 1 013 persons living in rural areas, were tested by if and cf; with the if-test, 4% of them were sero-positive (titer greater than or equal to: 20). if-tests are eightfold more sensitive than cf tests and have at least the same specificity. the results of two (commercial) coxiella burnetii phase ii antigens were compared. | 1984 | 6366707 |
| [detection of c. burnetii in wool swabs from naturally infected goats using a volumetric method of immunofluorescent analysis]. | | 1983 | 6367148 |
| [coexistence of legionnaires' disease and q fever in a single patient]. | a case of legionnaires' disease associated with q fever is presented; this is probably the first reported case of concomitant infections with legionella pneumophila and coxiella burnetii. the pulmonary features of the illness were not typical of either disease. the difficulties of making a diagnosis in such cases are discussed. | 1984 | 6367919 |
| [comparative studies of guinea pig and mouse tests for the detection of coxiella burnetii--and a study of q fever distribution in south and central hessen]. | | 1984 | 6368176 |
| [prevalence of q fever in indigenous cattle]. | | 1984 | 6368177 |
| comparison of phenol- and heat-killed antigens in the indirect immunofluorescence test for serodiagnosis of legionella pneumophila group 1 infections. | an antigen prepared with agar-grown legionella pneumophila group 1 killed by 0.5% phenol and suspended in 0.5% yolk sac was examined for use in the indirect immunofluorescence test for legionellosis and compared with a heat-killed antigen. the serological results of the two antigens for single and paired sera agreed well. morphological and staining characteristics were better for phenol-treated organisms. electron microscopy observation showed an apparently well-preserved cell surface. the backg ... | 1984 | 6386881 |
| a rapid immunofluorescent procedure for serodiagnosis of q fever in mice, guinea pigs, sheep, and humans. | the ability to diagnose q fever has been hampered by the fact that diagnosis depends upon difficult serologic tests such as complement fixation (cf) or slide immunofluorescence performed only at reference laboratories. a new quantitative solid phase fluorescent antibody test (fiax) has recently been developed and applied to measure antibodies in several microbial systems. the test takes less than 2 hr to perform and employs stable reagents. we have utilized this technique and developed a rapid i ... | 1983 | 6388964 |
| [q fever in the netherlands; a description of 33 case reports observed between 1979 and 1983]. | | 1984 | 6392902 |
| early diagnosis of q fever: detection of immunoglobulin m by radioimmunoassay and enzyme immunoassay. | the use of a radioimmunoassay and an enzyme immunoassay for early diagnosis of q fever is described, both of which are based on the igm antibody-capture principle. a commercially available phase ii antigen and a labeled, purified anti-q-igg of human origin were employed. with these tests q fever antibodies were detected earlier in the course of infection than with the complement fixation test. | 1984 | 6396092 |
| [q fever in cows with special reference to coxiella burnetii colonization of the udder]. | | 1984 | 6400460 |
| different antigenic properties of lipopolysaccharides isolated from coxiella burnetii in phase i and pure phase ii. | lipopolysaccharides (lpss) isolated from coxiella burnetii cells in phase i and pure phase ii behaved as antigens reacting in serological tests (passive haemolysis, passive haemolysis inhibition, complement-fixation, immunoprecipitation) with sera of rabbits immunized with c. burnetii strains in the corresponding phase. no cross-reactions were observed between lpss isolated from c. burnetii in phase i and phase ii, respectively. | 1983 | 6417946 |
| rickettsial antibody prevalence in southern israel: igg antibodies to coxiella burnetii, rickettsia typhi, and spotted fever group rickettsiae among urban- and rural-dwelling and bedouin women. | a retrospective serological survey was carried out using sera obtained from women at childbirth in the southern desert region of israel to determine exposure experience to three rickettsial agents: coxiella burnetii, rickettsia typhi, and spotted fever group rickettsiae. using the indirect fluorescent antibody method for determining igg antibodies, it was found that about 40% of all sera examined demonstrated antibodies to one or more rickettsiae. bedouin women appeared to be at greater risk of ... | 1983 | 6418016 |
| monoclonal antibodies distinguish phase variants of coxiella burnetii. | monoclonal antibodies (mabs) directed against phase i and ii variants of coxiella burnetii were produced by fusing myeloma sp2/o-ag 14 cells with spleen cells from mice immunized with the chloroform-methanol extraction residue of phase i whole cells. two hybridoma clones which distinguished the phase variants by microimmunofluorescence assay were isolated and characterized. the mabs showing specificity for phase i cells (mabi-1, immunoglobulin g, subclass 3 kappa) reacted with the hot phenol-wat ... | 1984 | 6418662 |
| importance of viruses and legionella pneumophila in respiratory exacerbations of young adults with cystic fibrosis. | from january to april 1980 46 young adults with cystic fibrosis were studied for evidence of infection with a wide variety of microorganisms, including viruses and legionella pneumophila. two groups of patients were investigated: a "deteriorated" group of 24 patients who had experienced an increase in lower respiratory tract symptoms and fall in lung function values in the course of one month before the start of the study and a "stable" group of 22 patients with no such deterioration. all serolo ... | 1984 | 6422578 |
| [respiratory tract infections caused by viruses, mycoplasma, rickettsia and chlamydia with bronchial and pulmonary localization]. | | 1984 | 6424057 |
| interferon-gamma inhibits growth of coxiella burnetii in mouse fibroblasts. | we studied the effects of various mouse interferon preparations on the growth of coxiella burnetii in mouse fibroblasts. the addition of both recombinant interferon-gamma and a crude lymphokine preparation that contained interferon-gamma to infected l929 cells inhibited the growth of c. burnetii, whereas the addition of a crude preparation of type i interferons did not. cycloheximide suppressed the inhibitory effects of recombinant interferon-gamma and crude lymphokines. | 1984 | 6432701 |
| [serological study of the presence of antibodies against coxiella burnetti and brucella abortus in veterinarians in the netherlands]. | two hundred and twenty-two large animal practitioners in the netherlands were studied serologically for the presence of antibodies to coxiella burnetii (q-fever) and brucella abortus. eighty-four percent showed antibodies to coxiella burnetii, which were equally distributed over all age-groups. for blood donors the proportion in men was 31 per cent and 14 per cent in women, also equally distributed over all age-groups. in the case of brucella abortus, the number of veterinarians showing antibodi ... | 1984 | 6435281 |
| chemical and immunological characterization of lipopolysaccharides from phase i and phase ii coxiella burnetii. | lipopolysaccharides (lpss) isolated from phase i and phase ii coxiella burnetii (lps i and lps ii, respectively) were analyzed for chemical compositions, molecular heterogeneity by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, and immunological properties. the yields of crude phenol-water extracts from phase i cells were roughly three to six times higher than those from phase ii cells. purification of lpss by ultracentrifugation gave similar yields for both lps i and lps ii. purifie ... | 1984 | 6438066 |
| epidemiological studies of q fever in the area of dzhambul in the kazakh ssr. | the frequency of q fever in the area of dzhabmul varies from 1.0 [district of kurdayi, 1968] to 18.1 [district of talass, 1972] for 100,000 inhabitants. the lower incidence of q fever in the rural population, compared to that of inhabitants of towns, is closely associated with the development of early immunity. farm animals are the main source of infection. the persistent circulation of rickettsia burneti among wild life is maintained by wild mammallans and ticks ixodes. | 1980 | 6447720 |
| [vaccination against q fever in occupationally exposed persons in the district velký kritís (author's transl)]. | | 1981 | 6451301 |
| computed tomographic brain scan findings in q fever encephalitis. | neurological involvement in q fever is unusual. we present a case of encephalitis due to coxiella burnetii with neuroradiologic findings on ct not described previously, consisting in areas of decreased absorption coefficient in the subcortical white matter of both hemispheres, predominantly in the right. differential diagnosis must be established from viral encephalitis, of similar clinical presentation, which may show similar ct lesions to those in this case. | 1984 | 6462442 |
| unsuspected q fever endocarditis--a case report. | | 1984 | 6464235 |
| induction of hyperreactivity to endotoxin in mice by coxiella burnetii. | intraperitoneal inoculation of mice with live or killed coxiella burnetii phase i or phase ii cells induced a marked hyperreactivity to the lethal effect of bacterial endotoxin and was accompanied by a marked hepatosplenomegaly. the degree and duration of hyperreactivity depended on the dose of c. burnetii administered and were higher with phase i than with phase ii cells. sensitization to the lethal effects of endotoxin and induction of splenomegaly by phase i c. burnetii cells also proceeded i ... | 1984 | 6469358 |
| [early-onset endocarditis on a heart valve prosthesis caused by coxiella burnetii]. | | 1984 | 6473877 |
| tick-borne rickettsioses in pune district, maharashtra, india. | an extensive study on tick-borne rickettsioses in the pune district of maharashtra revealed that indian tick typhus exists as a zoonosis, which only occasionally causes disease in man. by sero-conversion in guinea pigs, presumptive isolates of rickettsia conori and coxiella burnetii were recovered from 4 of the 11 species of ticks examined. boophilus microplus and rhipicephalus haemaphysalis were found to be harbouring r. conori whereas c. burnetii was isolated from haemaphysalis intermedia and ... | 1984 | 6500861 |
| biochemical and immunological properties of coxiella burnetii cell wall and peptidoglycan-protein complex fractions. | coxiella burnetii morphological cell types were fractionated into large-cell variant cell walls, two fractions of small-cell variant cell walls, and one fraction of small-cell variant whole cells. based on the contents of peptidoglycan (pg)-constituents and the yields of the sodium dodecyl sulfate-insoluble pg-protein complex (pg-pc) from cell walls, the fraction of large-cell variant cell walls contained significantly less pg than did the fraction of small-cell variant cell walls. the yields of ... | 1984 | 6501233 |
| sensitivity of coxiella burnetii peptidoglycan to lysozyme hydrolysis and correlation of sacculus rigidity with peptidoglycan-associated proteins. | the protease-resistant proteins associated with the peptidoglycan (pg) of the phase i small-cell variant coxiella burnetii were either partially released from the pg by boiling the pg-protein complex (pg-pc) in sodium dodecyl sulfate containing 2-mercaptoethanol and edta or totally released by 1 n naoh hydrolysis at 23 degrees c. an 18,300-dalton protein was released from the pg-pc under reducing conditions, whereas 1 n naoh treatment extracted pg-associated proteins without apparent dissolution ... | 1984 | 6501234 |
| the radiographic features of epidemic and sporadic q fever pneumonia. | radiographic dissimilarities exist between the chest radiographs of patients with epidemic and sporadically-occurring q fever pneumonia. chest radiographs of 25 patients with q fever pneumonia were retrospectively assessed, and demonstrated previously unreported differences between these two broad groups. differing strains of coxiella burnetii, or varying doses of the pathogen, are postulated as the pathogenetic mechanisms for the observed discrepant findings. | 1984 | 6501384 |
| [epidemiology of q fever in hesse: studies using enzyme immunoassay and the complement fixation reaction]. | | 1984 | 6525159 |
| [pulmonitis caused by coxiella burneti and chlamydia psittaci. 2 years of research in marche]. | this paper point to infections caused by chlamydia psittaci and coxiella burneti in a region of the middle italy (marche) from april 1981 to march 1983. 32 of 686 cases (about 5%) of pneumonia were diagnosed as q fever or ornithosis-psittacosis. the role of the research of these etiologies in routine diagnostic work on acute respiratory infections is underlined. | 1984 | 6534399 |
| coxiella burnetii antibodies in some nigerian dairy cows and their suckling calves. | dairy cows and their suckling calves kept at institutional and governmental farms under semi-intensive husbandry and dual purpose fulani nomadic herds with extensive management system around zaria, nigeria were screened for antibodies against coxiella burnetii using the capillary agglutination test (cat). an antibody prevalence of 59.8% detected among 306 dairy cows under both management systems was significantly (p less than 0.01, x2) higher than was found among their suckling calves where 41.0 ... | 1984 | 6534901 |
| [a survey of q fever at the shore of lake aibi, boertala area, xinjiang autonomous region]. | | 1984 | 6536371 |
| [rickettsiosis and chlamydiosis in hoggar (republic of algeria): epidemiological sampling]. | the study was made on reservoirs of infections (rodent, sheep, goat, dromedary), vectors (louse) and human-receptors. examinations were made on smears examined with staining and indirect-fluorescente techniques and on sera examined by complement fixation test. chlamydia psittaci appears very often in rodent, sheep, goat, dromedary and man. antibodies against coxiella burneti were found present in sheep, goat but mainly in dromedary and less than 16 years old boys. two lice were carrier of ricket ... | 1984 | 6548418 |
| active transport of proline by coxiella burnetii. | the obligate intracellular rickettsia, coxiella burnetii, was shown to possess an energy dependent proline transport system which displayed a high degree of specificity and was highly dependent on ph. transport was maximal at ph 3.0 to 4.5, a ph range approximately that of the host cell phagolysosome where the agent replicates. transport was inhibited by the uncouplers carbonyl cyanide m-chlorophenylhydrazone and dinitrophenol, but not by sodium arsenite. in the presence of glutamate, a preferre ... | 1984 | 6549343 |
| [experience with vaccination of humans against q fever in czechoslovakia]. | | 1983 | 6616283 |
| [distribution of coxiella burnetti: a seroepidemiological study of domestic animals and veterinarians]. | | 1983 | 6635645 |
| dermal granulomatous hypersensitivity in q fever: comparative studies of the granulomatous potential of whole cells of coxiella burnetii phase i and subfractions. | dermal granulomatous reactivity to q fever antigens in guinea pigs has been described as a model for vaccine reactions seen in previously sensitized humans. this model has now been applied to study the ability of subfractions of coxiella burnetii to produce granulomas. q fever organisms in phase i, trichloroacetic acid-soluble and -insoluble fractions, and the extract and residue of chloroform-methanol extraction were tested for their relative ability to elicit and immunize for dermal granulomat ... | 1983 | 6642669 |
| mosquito inoculation technique for the diagnosis of q fever employing an animal model. | | 1983 | 6654408 |
| abortion and stillbirth associated with chlamydia psittaci var ovis in dairy goats with high titers to toxoplasma gondii. | during two consecutive breeding seasons in a brucellosis-free dairy goat herd, approximately 40% to 70% of the does (mean herd size, 14.5) had stillbirths or aborted. none of the does aborted or had stillbirths twice. in the first breeding season, 9 of 13 does aborted in the last 2 months of gestation. three fetuses and 2 fetal placentas from 2 does were examined. microscopic findings included severe multifocal hepatic necrosis, mild pneumonia, and mild multifocal necrosis in the brain. cultures ... | 1983 | 6654724 |
| endocarditis due to q fever in nova scotia: experience with five patients in 1981-1982. | q fever endocarditis is rarely reported in north america; only four cases have been documented since 1953. in 1981-1982, five cases were identified in the victoria general hospital, halifax, nova scotia. four patients were from widely separated areas of nova scotia and one was from prince edward island. four patients with long-standing valvular abnormalities, including two with prosthetic valves, presented with recurrent febrile episodes. the fifth patient, who was previously well, had recurrent ... | 1983 | 6655300 |
| [dynamics of the humoral immunity indices in laboratory animals multiply infected with coxiella burnetii]. | | 1983 | 6670107 |
| [microagglutination with rickettsia of q fever]. | | 1983 | 6675859 |
| elisa in the q fever diagnosis. | | 1983 | 6678571 |
| antibody-dependent cellular cytotoxicity of coxiella burnetii-infected j774 macrophage target cells. | cell-mediated immunity is clearly the critical host defense mechanism against human coxiella burnetii infection (q fever); the role of specific antibody is unclear. by using a mouse macrophage tumor cell line, j774, persistently infected with c. burnetii phase i organisms, in a standard 51cr-release cytotoxicity assay, we explored the possibility that antibody-dependent cellular cytotoxicity may be immune mechanism in q fever. after 16 h of incubation in the presence of immune sera from q fever ... | 1984 | 6690402 |
| chronic q fever. | | 1984 | 6699410 |
| q fever: hazard from sheep used in research. | the recent recognition that q fever is endemic in ontario and the known occupational risk of q fever to research personnel working with sheep prompted a study to determine the prevalence of antibodies to the causative organism, coxiella burnetti, in animals and staff at a toronto animal research institute. of 37 sheep 34 (92%) were found to be seropositive--that is, to have a titre of complement-fixing antibody to the phase ii antigen of 1:8 or greater. of 331 staff members tested, 18% were foun ... | 1984 | 6704847 |
| seroepidemiology of q fever in nova scotia and prince edward island. | the prevalence of coxiella burnetti infection (q fever) was determined among nova scotia (n.s.) and prince edward island (p.e.i.) blood donors by using the complement fixation and microimmunofluorescence (if) test. the complement fixation and if antibody tests measured antibody prevalence for the phase ii or phase i and ii antigens, respectively. complement-fixing antibodies to phase ii antigen were detected in 4.1% of 997 n.s. and 5.0% of 219 p.e.i. blood donors. anti-phase ii antibodies were d ... | 1984 | 6713300 |
| [modification of antibody formation in animal experiments by glucocorticoids and aristolochic acid]. | in the bone marrow of guinea pigs a decrease of lymphocytes resulted after immunisation against q-fever antigen, compensating within 4 weeks. under treatment with prednisolone normalisation occurred within 3, with aristolochic acid as well as with prednisolone and aristolochic acid already up to the 2nd week. after immunisation plasma cell increase was lasting longer in the aristolochic acid group than in other groups. the antibody determinations resulted in different values. after immunisation ... | 1984 | 6719965 |
| [susceptibility of ornithodoros papillipes (argasidae) ticks to the rickettsia coxiella burnetii]. | a definition of susceptibility of an arthropod to an infectious or invasional agent is given. the susceptibility means a capacity of the arthropod for infection in a result of which the agent either completes a part of its life cycle in the organism of its invertebrate host or reproduces repeatedly in the organs and tissues of its internal medium causing or not causing a noticeable damage. on the model of the tick o. papillipes and q. fever agent there were shown differences in the resistance of ... | 1984 | 6728511 |
| [results of a study of q fever in odessa province]. | | 1984 | 6741363 |
| the role of the house fly (musca domestica l.) in the transmission of coxiella burnetii. | the flies which are fed a single rickettsia suspension keep their infectivity throughout their life and can contaminate environment as long as that. under conditions of experiment their life span is 32 days. coxiella burnetii survives in the faeces of flies as long as 80 days, in the dead flies as long as 90 days. | 1984 | 6745799 |
| the biology of rickettsiae. | | 1982 | 6756292 |
| [udder colonization with coxiella burnetii in cattle q fever]. | | 1982 | 6756861 |
| [elaboration and trial of an erythrocyte immunoglobulin diagnostic preparation for detecting coxiella burnetii]. | | 1981 | 6764963 |
| development and characterization of high-titered, group-specific fluorescent-antibody reagents for direct identification of rickettsiae in clinical specimens. | rabbits were inoculated with purified antigen preparations of coxiella burnetii and representative species of the spotted fever and typhus groups of rickettsiae. their antibody responses were monitored by complement fixation tests; high-titered antisera were fractionated with ammonium sulfate and then labeled with fluorescein isothiocyanate by the dialysis method. the conjugates had homologous 3+ staining titers of 1:256 to 1:2,048 and did not exhibit nonspecific staining. the rickettsia rickett ... | 1980 | 6769955 |
| [current status of vaccine treatment of zoonotic infections]. | | 1980 | 6776687 |
| seroprevalence of brucellosis and q fever in dairy animals. | | 1980 | 6781180 |
| platelet aggregation and stimulation of leucocyte procoagulant activity by rickettsial lipopolysaccharides in rabbits and in man. | the effects in vitro of 4 purified lipopolysaccharide (lps) preparations from rickettsiae on platelets and leucocytes were studied in rabbits and in man. all lps induced aggregation in rabbit platelet-rich plasma but to differing degrees. this activity was abolished by inactivation of complement. none of the preparations induced aggregation of human platelets. both rabbit and human leucocytes, when incubated with each of the rickettsial lps preparations, generated a potent procoagulant activity ... | 1981 | 6781928 |
| fatty acid composition of rickettsiae. | the fatty acid compositions of selected strains of rickettsiae were studied by gas-liquid chromatography. the profiles of all the rickettsiae except coxiella burnetii were qualitatively similar. the fatty acid composition of c. burnetii was similar to that of certain legionella species. | 1981 | 6787071 |
| rickettsioses surveillance in animals and man in uttar pradesh. | | 1982 | 6816730 |
| intracellular fate of phase i coxiella burnetii in guniea pig peritoneal macrophages. | cultivated guinea pig peritoneal macrophages were infected with radio-labeled phase i coxiella burnetii in order to assess the intracellular distribution of ingested rickettsiae. localization of organisms was determined by fractionation of macrophage homogenates by equilibrium density centrifugation on sucrose gradients. macrophages isolated from either nonimmune or immune guinea pigs and infected with c burnetii opsonized with immune serum yielded equilibrium density distribution for rickettsia ... | 1983 | 6842464 |
| lysosomal response of a murine macrophage-like cell line persistently infected with coxiella burnetii. | the lysosomal response of a murine macrophage-like tumor cell line (j774) during persistent infection with coxiella burnettii was examined. by using acid phosphatase as a lysosomal marker, it was shown that phagosome-lysosome fusion occurred in j774 cells persistently infected with c. burnetii. this observation was verified using thorium dioxide, an electron-dense compound that is sequestered in secondary lysosomes. the phagolysosomes contained viable replicating rickettsiae. spectrofluorometric ... | 1983 | 6852916 |
| [experiences and recent data on coxiella burnetii infection (q fever). 1]. | | 1983 | 6857638 |
| [continuous multiplication of coxiella burnetii through persisting infection in buffalo-green monkey (bgm) cell cultures]. | | 1983 | 6858466 |
| [q fever. apropos of 13 case reports]. | | 1983 | 6865556 |
| [experiences and current knowledge of coxiella burnetii infection (q fever). 2]. | | 1983 | 6868062 |
| chronic or fatal q-fever infection: a review of 16 patients seen in north-east scotland (1967-80). | sixteen patients with serologically proven q-fever infection are reviewed. fifteen had significantly raised antibody titres to both phase i and phase ii coxiella burneti antigens, indicating persistent or chronic infection. one patient, a premature infant who died, had raised phase ii titres only, but is included together with the mother who had chronic q-fever and was the presumed source of infection. chronic q-fever infection has previously been regarded as virtually synonymous with q-fever en ... | 1983 | 6878620 |
| [how widespread is q fever in switzerland?]. | there are very few reports in the literature on mass seroepidemiological studies of the prevalence of q fever antibodies. those to be found are mostly concerned with focal epidemics of q fever. out of more than 2000 serum specimens from blood donors analyzed at random in switzerland in 1982 for q fever antibodies, 3.5% gave seropositive results (cbr titer at least 1:10). in selected population samples, e.g. forestry workers or vets, the prevalence was distinctly higher (7.6% and 25.7%). contact ... | 1983 | 6879140 |
| [q fever in pregnant women and its effect on the fetus and newborn infant]. | | 1983 | 6881465 |
| serological evaluation of o fever in humans: enhanced phase i titers of immunoglobulins g and a are diagnostic for q fever endocarditis. | serological parameters were compared in 15 cases of coxiella burnetii infection comprising 5 cases each of primary q fever, chronic granulomatous hepatitis, and endocarditis. the diagnosis was made on the basis of clinical history and serology and on the isolation of c. burnetii phase i from biopsy specimens of liver and bone marrow from two patients with granulomatous hepatitis and from the aortic valve vegetations of five patients with endocarditis. the temporal sequences of immunoglobulin lev ... | 1983 | 6885155 |
| occurrence of rickettsioses in the lithuanian soviet socialist republic. | | 1981 | 6894581 |
| serological study with rickettsial antigens in erythema chronicum migrans. | 21 sera of 13 patients with erythema chronicum migrans (ecm) and related diseases were examined for the presence of antibodies against 14 rickettsial antigens by using 3 serological techniques in 2 laboratories. most tests were negative. this indicates that ecm and related diseases are not due to an hitherto known rickettsia. 5 out of 158 tests showed, however, positive reactions in low titers against rickettsia akari and coxiella burnetii. thus, an antigenic relationship may exist between one o ... | 1981 | 6895877 |
| [problem of q-rickettsial infection from ecological and epidemiological viewpoints]. | | 1980 | 6895955 |
| q fever control measures: recommendations for research facilities using sheep. | q fever (query fever) is a zoonosis caused by the rickettsia coxiella burnetii. domestic ungulates such as sheep, cattle, and goats serve as the reservoir of infection for humans and shed the desiccation-resistant organism in urine, feces, milk, and especially in birth products. in humans the illness is generally mild; however, q fever hepatitis is often seen and q fever endocarditis is an uncommon, but frequently fatal complication. q fever long has been recognized as an occupational hazard amo ... | 1982 | 6924645 |
| biochemical stratagem for obligate parasitism of eukaryotic cells by coxiella burnetii. | coxiella burnetti, the etiologic agent of q fever, is an oligate intracellular parasite of eukaryotes. unlike the majority of successful bacterial parasites, which escape the bactericidal environment of the phagolysosome by various means, c. burnetii multiplies only in the phagolysosome. in view of the relatively harsh environment inhabited by c. burnetii, we have examined (i) the in vitro metabolism of glucose and glutamate by whole cells of c. burnetii under conditions designed to approximate ... | 1981 | 6942430 |
| q fever endocarditis. | despite a worldwide distribution of coxiella burnetii, only single cases of q fever endocarditis have been reported outside great britain and australia. we present 10 patients; five were female, only four had a history of environmental exposure, and the mitral valve was involved as commonly as the aortic stenosis, and three patients had a prosthetic valve. we confirm the importance of hepatic involvement, thrombocytopenia and hypergammaglobulinemia as diagnostic features. diagnosis was establish ... | 1982 | 6977271 |
| immunogenicity and reactogenicity of a q fever chemovaccine in persons professionally exposed to q fever in czechoslovakia. | an immunization trial carried out on 1310 persons professionally exposed to q fever confirmed the suitability of a chemovaccine for field use. its immunogenicity and reactogenicity differed in three groups of subjects who differed in their previous experience of q fever and who were given different lots of the vaccine. there was some correlation between reactogenicity of the vaccine and pre-immunization positivity in the microagglutination and skin tests as indicators of a previous exposure. the ... | 1982 | 6982774 |
| q fever in india: a review. | | 1980 | 7005351 |
| [survival capacity of chlamydiae and coxiella burnetii under environmental conditions (author's transl)]. | | 1980 | 7006982 |
| prevalence of rickettsial antibody and cell-mediated reaction in cynomolgus monkeys (macaca fascicularis). | serologic studies on feral, colony-held cynomolgus monkeys indicated that 61% reacted to coxiella burnetii antigens, and 36% reacted to rickettsia conorii antigens. the results suggest that a high percentage of cynomolgus monkeys have been exposed to these organisms. | 1980 | 7007722 |
| q fever in finland: clinical, immunological and epidemiological findings. | clinical, immunological and epidemiological features of 14 human cases of q fever diagnosed at aurora hospital are presented. all patients had an acute febrile disease and 9 (64%) had respiratory symptoms, 4 (29%) verified pneumonia, and 9 (64%) hepatitis, which in 4 biopsied cases proved to be granulomatous. presence of circulating immune complexes was shown in 10/11 patients investigated by the platelet aggregation test (pat) and the platelet iodinated protein a (pipa) test. q fever is not kno ... | 1981 | 7017906 |
| protein synthesis in cell-free extracts of coxiella burnetti. | some aspects of protein biosynthesis were investigated in extracts of the obligate intracellular bacterium coxiella burnetti. sucrose gradient analysis revealed small quantities of 30s and 50s ribosomal subunits, few 70s ribosomes and no polysomes. functional endogenous mrna was not detected. in translation of exogenously added poly(u), extracts required mg2+ (17 mm) and nh4+ (60 mm) for optimal polyphenylalanine synthesis; the optimum mg2+ requirement differed from that of escherichia coli. the ... | 1980 | 7021761 |
| decreasing prevalence of q fever in illinois. | there were 858 (37.7 percent) q fever-infected dairy herds among the 2,277 tested in illinois in 1963. the percentage decreased to 19.2 percent (380 of 1,975) in 1967. reaction rates (complement-fixation test titer of 1:8 or greater) in serum samples from veterinarians decreased from 13.3 percent in 1956 to 3.9 percent in 1964 and from 3.6 percent in 1966 to 0 percent in 1968, 1970, 1972. there were 14 (2.7 percent) reactive serum samples among 526 abattoir workers tested in 1966; reaction rates ... | 1982 | 7063599 |
| biological and immunological properties of coxiella burnetii vaccines in c57bl/10scn endotoxin-nonresponder mice. | vaccines prepared from formalin-killed whole cells of coxiella burnetii (ohio strain) or from chloroform-methanol residue (cmr) and extract (cme) of such cells were examined for biological and immunological properties in male c57bl/10scn endotoxin nonresponder mice. vaccines containing killed whole cells induced a high incidence of gross pathology, as evidenced by liver necrosis, significant splenomegaly, and significant hepatomegaly in mice. the degree and onset of these pathological changes we ... | 1982 | 7068212 |
| q fever hazards from sheep and goats used in research. | two recent outbreaks of q fever in research institutions prompted the authors to review extant data, in an effort to delineate hazards to humans from small ruminants used in research. prevalence of q fever antibodies was 24% among 2097 sheep and 57% among 1475 goats from various sources. in a facility using sheep for prenatal research, in which an epidemic of human q fever later occurred, antibody prevalence among sheep was 77%, with larger than usual proportions of high (greater than or equal t ... | 1982 | 7073323 |
| a preliminary report on serum enzyme changes in guineapigs infected with coxiella burnetii. | | 1982 | 7106889 |
| q fever: a study of 111 consecutive cases. | | 1982 | 7110006 |
| [a case of q fever]. | | 1982 | 7135362 |
| lipid a in legionella pneumophila. | | 1982 | 7136354 |
| [coxiella burnetii infection. apropos of 10 cases]. | | 1982 | 7144289 |
| multiplication of coxiella burnetii in aedes aegypti. | | 1982 | 7174009 |
| serologic survey for certain zoonotic diseases in black bears in california. | black bears (ursus americanus) from 3 geographic areas of california were tested for antibodies against agents of 6 zoonotic diseases: toxoplasmosis (indirect hemagglutination), q fever (microagglutination), trichinosis (latex particle agglutination), botulism (passive hemagglutination), leptospirosis (plate agglutination), and plague (enzyme-linked immunosorbent assay). of 149 sera tested, 40 (27%) were positive for toxoplasma gondii antibodies and 25 (17%) had antibodies against coxiella burne ... | 1982 | 7174445 |
| [control of q fever]. | | 1982 | 7179235 |
| natural occurrence of coxiella burnetii in the brown dog tick rhipicephalus sanguineus. | | 1980 | 7191407 |
| [q fever in the etiology of spontaneous abortion]. | | 1981 | 7212210 |
| role of antibody in coxiella burnetii infection. | balb/c mice infected with coxiella burnetii phase i developed a state of acquired resistance which could be detected during week 2 postinfection. immune serum, administered to normal mice 24 h before challenge with c. burnetii, appeared to accelerate the development of resistance. an increased clearance rate could be measured in these serum recipients 1 week postinfection. simultaneous administration of immune serum and c. burnetii did not affect the normal clearance rate of rickettsiae from the ... | 1981 | 7216465 |
| efficacy of translation in the rickettsia coxiella burnetii. | the addition of coliphage q beta ribonucleic acid to a cell-free translation system obtained from coxiella burnetii cells caused the formation of monosomes and disomes from ribosomal subunits and resulted in synthesis of viral coat protein. rickettsial ribosomes and associated translation factors functioned together, with fidelity, efficiency, and a specificity similar to those of free-living gram-negative bacteria. | 1981 | 7217018 |