| ph measurements in the vascular wall of dogs with electrically induced thrombosis of the femoral artery. | electrically induced thrombosis is often used for pathophysiologic and therapeutic experiments. the ph value of the vascular wall was measured to approach the features of this thrombosis. after inducing thrombosis by direct current, ph value of the intima of femoral artery was found decreased. the anode was inserted in the lumen. as to the behavior of the ph value, electric thrombosis and clinical thrombosis are similar. electric thrombosis therefore seems to be valuable for comparing investigat ... | 1977 | 15352 |
| hormonal control of zinc uptake and binding in the rat dorsolateral prostate. | the zinc uptake in the dorsolateral prostate of rats was studied after different hormonal manipulations. orchiectomy reduced the uptake of 65zn. administration of estradiol benzoate to orchiectomized rats doubled the 65zn uptake, a phenomenon which was not observed in orchiectomized-adrenalectomized rats. adrenalectomy in orchiectomized rats had no effect on the concentration of radioactivity beyond the castration-induced decrease. a prolactin release inhibitor, 6-methyl-8-erogelenylacetamide, r ... | 1977 | 15955 |
| reactions of cysteamine and other amine metabolites with glyoxylate and oxygen catalyzed by mammalian d-amino acid oxidase. | pig kidney d-amino acid oxidase [d-amino-acid:oxygen oxidoreductase (deaminating), ec 1.4.3.3] catalyzes a rapid uptake of oxygen when high concentrations (50-100 mm) of glyoxylate and the following amines are present under usual assay conditions (ph 8.3): cysteamine, 2-aminoethanol, putrescine, d,l-1-amino-2-propanol, d,l-2-amino-1-propanol, 3-amino-1-propanol, d,l-octopamine, ethylenediamine, and l-cysteine ethyl ester. notable physiological amines that do not support a rapid o2 reaction under ... | 1979 | 37501 |
| cell-mediated immune response in mice treated with steroidal contraceptives. | the splenomegaly assay (simonsen, 1962) was standardized using different strains of rats and mice. male wistar rat (donor)-female swiss mouse (host) was found to be the suitable combination that could be employed in subsequent experiments to study the potential of contraceptive steroids to alter cmir. the index of splenomegaly appeared to increase in case of mice treated with combination oral contraceptives (ovulen, ovral or enovid). the differences observed, however, neared significance only in ... | 1975 | 55327 |
| a serial study of pregnancy proteins in primigravidae. | the plasma concentrations from four 'pregnancy proteins' and three steroid hormones have been measured throughout pregnancy in 15 primigravidae. two of the proteins, human placental lactogen (hpl) and pregnancy-specific beta1-glycoprotein (psbetag), are specific for pregnancy and correlate well with the stage of gestation. it is suggested that measurement of psbetag may be useful in assessing feto-placental wellbeing. neither of the pregnancy-associated proteins, steriod-binding beta-globulin (s ... | 1976 | 57799 |
| equine markers genes. polymorphism for group-specific component (gc). | polymorphism of equine gc protein was demonstrated by immunofixation electrophoresis with a goat anti-human gc antibody. three different phenotypes, f, fs and s, were found. family data supported the genetic theory of two autosomal codominant alleles, gcf and gcs. both alleles occurred in standardbred, thoroughbred and arabian horses and in shetland ponies. a frequency of 0.23 for gcs in the american standardbred horse indicates the system should be useful for problems of identification and pare ... | 1978 | 84540 |
| fluorescence and electron microscope studies on the interaction between lysosomes of mammalian host-cells and toxoplasma gondii rh following treatment with cotrimoxazole [proceedings]. | | 1978 | 84590 |
| cross-reaction between the mycelial galactomannas of three hormodendrum strains and the mannans of two candida albicans strains of different serotypes, a and b. | cross-reactivity between galactomannans of three representative hormodendrum strains, h. pedrosoi ifo 6071, h. compactum ifo 6726, and h. dermatitidis ifo 6421, and the mannans of two candida strains, c. albicans nih a-207 (serotype a) and c. albicans nih b-792 (serotype b), were investigated by means of agar-gel double diffusion, quantitative preciptin reaction, and passive cutaneous anaphylaxis. the following results were obtained. (i) antisera to whole cells of three hormodendrum strains were ... | 1979 | 84792 |
| localization of nors in chromosomes of mouse cell lines by a combined 33258-hoechst and ag-staining technique. | | 1979 | 84805 |
| solid phase indirect radioimmunoassays for the rapid diagnosis of sindbis virus antigen. | indirect radioimmunoassays have been developed for the rapid detection of sindbis virus. dilutions of sindbis virus from tissue culture fluids have been immobilized and allowed to react with rabbit anti-sindbis virus antibodies. the bound antibodies were assayed either by 125i-labelled anti-rabbit igg-antibodies or alternatively by addition of human complement and 125i-labelled anti-human c1q antibodies or 125i-labelled protein a. | 1978 | 84855 |
| observations on the m-wave and the cnv in the squirrel monkey. | a typical cnv paradigm, with food as reward, evokes in the squirrel monkey's post-arcuate and post-central cortices both m-waves in response to the cues and what appears to be a cnv in the interstimulus interval. both wave forms appear to be generated locally in cortex and to be more closely related temporally to the cues than to the animal's behavioral response. the cnv, like the m-wave, appears to reflect the animal's level of interest in obtaining the reward. it is smaller when the animal mis ... | 1979 | 85525 |
| immunochemical characterization of the plasmin-antiplasmin system. basis for the specific detection of the plasmin-antiplasmin complex by latex agglutination assays. | | 1979 | 85679 |
| hippocampal eeg and behaviour in dog. ii. hippocampal eeg correlates with elementary motor acts. | a positive correlation has been shown between the speed of forced stepping on a conveyor belt and the amplitude and frequency of the concomitant hippocampal eeg. significant modulation in the spectral properties of the dog's hippocampal eeg has been found in relation to 3 elementary motor acts: stepping, respiratory movements and a reflex movement in reaction to linear acceleration of the animal. the findings support the idea that within a certain experimental situation the hippocampal eeg refle ... | 1979 | 88345 |
| [post-extrasystolic and post-pacing potentiation. ii. study by means of systolic time intervals in man]. | | 1978 | 88948 |
| cea-like antigens in different histologic types of human lung carcinoma. | comparative studies on the presence and immunological reactivity of cea and cea-like antigens in lung and digestive tract cancers were performed. specific goat and rabbit anti-cea immune sera were used. immunofluorescence studies revealed in histologically different types of the lung carcinomas the presence of the cross reacting antigen with classical cea. absorption procedures, and double diffusion tests have shown the existence of two at least antigenic determinants in cea molecule: 1. the det ... | 1979 | 89630 |
| differentiation of herpes simplex virus type 1 and type 2 by immunofluorescence: discriminative staining by labelled igg preparations. | while evaluating herpes simplex virus (hsv) typing by indirect immunofluorescence staining, an undesired specific staining pattern turned out to be a reliable marker for herpes simplex type 1. cells infected with herpes simplex type 1 displayed clear staining with a fitc-conjugated antiglobulin preparation, also in the absence of herpes simplex-specific antibodies. using the same conjugate, herpes simplex type-2-infected cells exhibited no fluorescence. the particular type of staining observed w ... | 1979 | 89761 |
| human blood t lymphocytes that suppress the mixed leukocyte culture reactivity of lymphocytes from hla-b14 bearing individuals. | a nontransfused male patient with recurrent bladder carcinomata has been demonstrated to have blood t lymphocytes that suppress the mlc responsiveness of lymphocytes only from normal individuals positive for hla-b14. unexpectedly, this t-suppressor cell differs from three other reported blood t-suppressor cells arising in man in that it apparently does not require hla-d locus compatibility between the suppressor cell and the lymphocyte being suppressed. | 1979 | 90092 |
| effects of anti-white matter serum on myelin and lipid synthesis in brain prisms. | tissue prisms prepared by choping whole mouse brain maintained respiratory capacity and ultrastructural integrity of 3 h in vitro. normal rabbit serum (ca. 25%) caused no morphological change but inhibited the synthesis of galactolipids by the prisms. heating the serum abolished the inhibition. complement containing anti-white matter rabbit serum destroyed myelin and inhibited galactolipid synthesis to a greater degree than did normal serum. structures other than myelin were unaffected by the an ... | 1979 | 90541 |
| procaine-induced seizures in epileptic monkeys with bilateral hippocampal foci. | intravenous procaine hcl given at low doses (0.5-2.5 mg/kg) to two monkeys with bilateral alumina hippocampal foci depressed interictal spiking or had little effect. at 5.0 mg/kg unilateral limbic activation occurred. at 10.0 mg/kg unilateral or bilateral limbic activation and generalized seizures could be evoked within 3-10 min. at higher doses (15 and 20 mg/kg) bilateral limbic activation or brief (one min) generalized seizures occurred. the unilateral-onset psychomotor seizures were not ident ... | 1979 | 91502 |
| shielding of phospholipid vesicles from phospholipase c hydrolysis by alpha-lactalbumin adsorption [proceedings]. | | 1979 | 92261 |
| immunologic regulation in pregnancy. | theories to explain the failure of rejection of the fetus by the mother during pregnancy include immunologic privilege of the uterus as a graft site, lack of transplantation antigen expression on the trophoblast, weakening of maternal cellular immunity during pregnancy, and separation of maternal and fetal circulations. evidence for and against each of these theories is discussed. local concentration of a variety of hormones, including human chorionic gonadotropin (hcg), sex steroids, alpha-feto ... | 1979 | 92318 |
| alpha-fetoprotein inhibits antibody binding to acetylcholine receptor. significance for myasthenia gravis and other autoimmune diseases. | | 1979 | 93589 |
| integration site of bovine leukemia virus dna in the bovine genome [proceedings]. | | 1979 | 93923 |
| antifetal and tumor-specific reactivity in human osteosarcoma. | | 1979 | 94187 |
| effect of 6-hydroxydopamine on baroreceptor-heart rate and nasopharyngeal reflexes of the rabbit. | | 1979 | 94399 |
| thyroxine-induced cardiomegaly: assessment of nucleic acid, protein content and myosin atpase of rat heart. | 1 mg/kg l-thyroxine was administered to rats for 14 days to evaluate the potential of the hyperthyroid state to induce heart hypertrophy and its effect on myosin adenosine-triphosphatase (atpase) activity. evidence of hyperthyroidism such as weight loss, elevation of rectal temperature, increased heart rate and oxygen consumption, was observed in all treated rats. cardiac enlargement was determined by comparison of wet and dry ventricle weights, myocardial rna, dna and protein content. wet and d ... | 1979 | 94743 |
| interaction of diphosphatidylglycerol with beef heart cytochrome c oxidase in reconstitution experiments [proceedings]. | | 1979 | 94792 |
| [faecal enzyme diagnostic (author's transl)]. | the hitherto existing results of determinations of enzymatic activities in stool are presented in this review. the chymotrypsin activity is diminished in advanced exocrine pancreatic insufficiency. the faecal alpha-amylase activity has up to now no significance in the diagnosis of pancreatic diseases. up to five amylolytic enzyme activities are detectable. the alkaline phosphatase is mostly of intestinal origin. up to 4 enzyme bands can be exhibited with the disc electrophoresis in polyacrylamid ... | 1979 | 94852 |
| synthetic antigens iii. antigen-binding cells to interpolymer of styrene and maleic acid psm and sheep red blood cells in mice immunized with psm. | studies on the immune response in mice to a new synthetic antigen interpolymer of styrene and maleic acid (psm) are described. the immune response was measured by determination of antigen binding cells by means of rosette test with psm-coated srbc, an unexpected effect was observed--besides rosette-forming cells for psm, rosette-forming cells and agglutinating antibodies for sheep red cells were found. the results presented in this paper suggest that psm is acting both as an immunogen and a poly ... | 1979 | 94989 |
| histochemical studies of mucosubstances and keratins of thymic corpuscles. | keratin and prekeratin have been visualized histochemically by testing the reactivity of disulfide groups in the thymic corpuscles of the sheep. rhesus monkey, rabbit and dog, and the reactivity of sulfhydryl groups in the sheep, rhesus monkey, rabbit and rat. ten to 50% of the thymic corpuscles showed keratinization by this method. acidic mucosubstances were visualized histochemically in the rhesus monkey, sheep and rat but not in the rabbit. staining for vic-glycol groups was prominent in all ... | 1979 | 94996 |
| [immunological problems in oncology (author's transl)]. | the authors, after a view of the problems of immunology, regarding the most recent discoveries, deal with the conclusions about the immunological reactions in research and clinical oncology. many specific antibodies, formed as a result of the tumor, have been discovered in the field of research. it is impossible to say the same about human tumors and the probable hypothesis are numerous. the results until now obtained, even if they don't give a definite response, show that the immune defense of ... | 1979 | 95475 |
| [the appearance of penicillin resistant gonococci. clinical, genetic and epidemiologic problems]. | | 1978 | 96408 |
| chromosomal locations of mouse immunoglobulin genes. | the chromosomal locations of the structural genes coding for the constant portions of mouse heavy (h) and light chain immunoglobulins were studied by molecular hybridization techniques. complementary dna probes containing the constant-region sequences of kappa and lambdai light chain and alpha, gamma2b, and mu heavy chain mrnas were annealed to a large excess of dna from a series of eight mouse-human hybrid cell lines that are deficient for various mouse chromosomes. the lines were scored as pos ... | 1978 | 96442 |
| multivalvular vegetations in a patient with enterococcal endocarditis diagnosed by echocardiography. | a patient with enterococcal endocarditis of 11 months' duration is presented, and the role of surgery and echocardiography is reviewed. echocardiography revealed vegetations of the aortic and mitral valves. after appropriate antibiotic therapy the patient had successful aortic and mitral valve replacement with porcine heterografts. enterococcal endocarditis is increasing in frequency and is likely to infect young women of childbearing age, elderly men who have had genitourinary tract manipulatio ... | 1978 | 96535 |
| the fate of bacteriophage phie transfecting dna. | | 1978 | 96585 |
| polarized light retinal photography of a monkey eye. | | 1978 | 96590 |
| clinical relevance of the liver-specific lipoprotein (lsp). | | 1978 | 96648 |
| effect of oophorectomy on estrogen receptors in rat mammary tumors induced by 7,12-dimethylbenz (a)anthracene. | | 1977 | 96813 |
| [effect of valinomycin on mitotic activity and ciliary movement during embryonic development]. | the k+ ionophore valinomycin very quickly arrests cleavage in sea urchin and mouse eggs at concentrations ranging between 10 and 3 micron. development of axolotl and xenopus eggs is not arrested before the blastula or gastrula stage. the motility of sea urchin sperm, blastulae and gastrulae is suppressed, within a few minutes, by 1-9 micron valinomycin. | 1978 | 96956 |
| [protective action on mice of acellular extracts from salmonella typhimurium]. | acellular fractions obtained by saline extraction at 60 or at 100 degree c of salmonella typhimurium protect mice against an experimental infection with the homologous strain. after purification, these fractions which are complex, might be used for the development of a vaccine. | 1978 | 97021 |
| local cerebral energy metabolism: its relationships to local functional activity and blood flow. | the results of studies with the [14c] deoxyglucose technique unequivocally establish that local functional activity in cerebral tissues is, as in other tissues, closely coupled to the local rate of energy metabolism. stimulation of local functional activity increases the local rate of glucose utilization; reduced functional activity depresses it. local cerebral blood flow is normally distributed among the cerebral structures in almost exact proportion to their rates of glucose utilization and it ... | 1978 | 97062 |
| experimental attempts to unmask effects of neural stimuli on cerebral blood flow. | | 1978 | 97066 |
| [suprachiasmatic nucleus, an hypothalamic regulation center of vital rhythmic functions]. | | 1978 | 97067 |
| lysosomal acid hydrolases of normal adipose tissues of man, monkey and rat. | | 1978 | 97094 |
| effect of pentagastrin on the rat small intestine after resection. | | 1978 | 97119 |
| lactase activity of microorganisms. | sixty-two strains of yeasts, molds and bacteria were screened for lactase (beta-d-galactosidase) activity. strains exhibiting the enzyme activity were evaluated for cell yield as well as enzyme units available per litre of the medium, per g cell dry weight and per mg protein of their cell-free extracts. the molds exhibited lowest enzyme activity but highest cell yields, bacteria produced lowest cell yield and maximum enzyme activity. cultures exhibiting very high activity among yeasts were sacch ... | 1978 | 97187 |
| regulation of the rate of beta-galactosidase synthese by the bgs and bgt loci in the mouse. | we have developed an assay for the in vivo rate of beta-galactosidase synthesis in mouse tissues to assess the mechanism by which the bgs and bgt loci regulate activity levels of this enzyme. genetically determined differences in liver and kidney beta-galactosidase content reflect equivalent differences in specific rates of enzyme synthesis. we conclude that bgs and bgt regulate beta-galactosidase activity by controlling the rate of synthesis of the beta-galactosidase molecule. | 1978 | 97289 |
| immunochemical studies of the inactivation of aspartate transcarbamylase by stationary phase bacillus subtilis cells. evidence for selective, energy-dependent degradation. | the aspartate transcarbamylase of bacillus subtilis is stable in exponentially growing cells, but undergoes rapid, energy-dependent inactivation when growth is inhibited by nutrient depletion or addition of antibiotics or other inhibitors of metabolism. this inactivation has been analyzed by a variety of immunochemical techniques, including direct and indirect immunoprecipitation of extracts of cells labeled with 3h-amino-acids, microcomplement fixation, and neutralization of enzymatic activity. ... | 1978 | 97299 |
| animal oral pigmentations. | | 1978 | 97376 |
| [transplantation of the big toe from the foot to the hand in monkeys using a microsurgical technic]. | | 1978 | 97465 |
| air caloric stimulation with tympanic membrane perforation. | warm air caloric stimulation in an ear with tympanic membrane perforation or mastoidectomy cavity often causes contralateral nystagmus. secondary nystagmus is common. our evidence with squirrel monkeys and patients indicates that the primary "inversion" results from endolymph cooling due to evaporative cooling due to evaporative cooling of the mucus lining the middle ear cavity, by the dry air stimulus. disconjugate horizontal nystagmus was found in a patient with large eardrum perforation, afte ... | 1978 | 97478 |
| mr. pechsniff's horse? (psychodynamics in compulsive drug use). | | 1977 | 97538 |
| [epidemic cerebrospinal meningitis and anti-meningococcic vaccination]. | | 1978 | 97747 |
| localization of primate calls by old world monkeys. | monkeys (macaca) were trained by operant conditioning techniques to report the minimum detectable change in location of a sound in space, and were tested with a series of recorded coo or clear call vocalizations. acuity of localization varied from approximately 4 degrees to 15 degrees and was a function of the magnitude of the change in pitch (frequency modulation) of the different clear calls. | 1978 | 97785 |
| alterations of intercellular junctions in acinic cell carcinoma of the canine pancreas. | intercellular junctions in spontaneous canine pancreatic acinic cell adenocarcinomas were compared to those in control canine pancreas. the neoplastic cells displayed proliferation and fragmentation of tight junctions and reduction in size and number of gap junctions. marked decrease in desmosomal density was observed only in the poorly differentiated carcinoma. in the well differentiated carcinomas a few of the desmosomes were characteristic of those found in squamous cells. no quantatitive or ... | 1978 | 97855 |
| [the qualification of different ditetrazolium salts as indicators in the oxido-reductase histochemistry (author's transl)]. | 15 ditetrazolium salts were examined to prove their qualities for histochemical techniques. the succinate dehydrogenase, the lactate dehydrogenase and the diaphorase i in hearts, muscles, livers, kidneys and brains of rats were demonstrated for it. the results show that nbt is the best allround tetrazolium salt for the histochemical demonstration of dehydrogenases. for the study of special questions it is suitable to use other tetrazolium salts, too. | 1978 | 97910 |
| effect of low temperature on growth, viability, and synthesis of mycolic acids of mycobacterium tuberculosis strain h37ra. | cultures of mycobacterium tuberculosis strain h37ra were grownto early logarithmic phase at 37 degrees c and were incubated at 16 degrees, 20 degrees, and 25 degrees c. the decrease in this ability was more rapid at 20 degrees c than at 16 degrees c. low-temperature incubation caused decreases in the ratios of mycolic acids and monounsaturated c16-19 fatty acids relative to the total of fatty acids synthesized. it also caused an increase in the ratio of saturated c24-26 fatty acids relative to ... | 1978 | 98081 |
| trh-like immunoreactivity in urine, serum and extrahypothalamic brain: non-identity with synthetic pyroglu-hist-pro-nh2 (trh). | trh-like immunoreactive substances obtained from several areas of rat brain and from human serum and urine were chromatographically separated by tlc and the resulting immunoreactive 'elution profiles' compared with that obtained for pyroglu-hist-pro-nh2 (trh). for hypothalamus and septal-preoptic samples trh was present, but represented less than 100% of the immunoreactive substances. for cortex, amygdala, brain stem, serum and urine, no trh was detectable in the immunoreactive substances from t ... | 1978 | 98209 |
| analgetic actions of intrathecal opiates in cat and primate. | | 1978 | 98219 |
| [investigations of the incidence of neisseria gonorrhoeae on the pharyngeal mucosa (author's transl)]. | | 1978 | 98235 |
| experimental coronary atherosclerosis in rabbits. | | 1978 | 98302 |
| vasodilation, fibrinolysis, and thrombolysis with intraarterial infusion of urokinase in the canine superior mesenteric artery. | urokinase, the plasminogen activator from human urine, produces a dose-dependent increase in blood flow in the canine superior mesenteric artery when injected intraarterially at doses from 10(-1) to 10(3) units kg-1. this vasodilation persists despite blockade of beta-adrenergic and histamine h1 and h2 receptors as well as inhibition of plasminogen activation, suggesting that these mechanisms are not involved. infusion of urokinase at 10(2) cta (committee on thrombolytic agents) units kg-1 min-1 ... | 1978 | 98390 |
| experimental fractures of monkey mandibles. | forty vervet monkey half mandibles, 20 with unerupted third molars and 20 with erupted third molars, were partially embedded in acrylic and loaded in an instron tensiometer. mandibles with unerupted third molars fractured at 15.8 +/- 2.5 kg while those having erupted third molars fractured at 26.4 +/- 4.2 kg. mandibles having unerupted third molars were shown to be significantly weaker than the mandibles with erupted third molar (t = 8.45, p less than 0.001). | 1978 | 98455 |
| immunization with dextransucrases, levansucrases, and glycosidic hydrolases from oral streptococci. ii. immunization with glucosyltransferases, fructosyltransferases, and glycosidic hydrolases from oral streptococci in monkeys. | the feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. forty rhesus monkeys, macaca mulatta, were used. cariogenic streptococci, s mutans, were implanted into all the monkeys' mouths. there was no pathological effect resulting from immunization. of the 40 animals, 30 retained the implanted flora throughout the experiment; the remaining 10 were reimplanted until the streptococci remained. in six months, gross carious lesio ... | 1977 | 98540 |
| visual-field displacements in human beings evoked by accoustical transients. | sixty-two of 133 subjects reported visual-field displacements when they were exposed to intense (125 db spl) repetitive audiofrequency transients. this phenomenon was investigated in three experiments. frequency (100-5000 hz) was varied in experiment i; repetition rate (0.5/s--6.0/s) was varied in experiment ii; acoustical transient onset/offset time (0.2--25 ms) was examined in experiment iii. the results of these three experiments indicated that the largest proportion of displacement reports a ... | 1978 | 98550 |
| evidence that bovine conglutinin reacts with an early product of c3b degradation, and an improved conglutination assay. | when eac43b were treated with heated serum in edta, reactivity with bovine conglutinin appeared rapidly, even at 0 degrees c, and almost simultaneously with the loss of c3b rosetting capacity. at the time conglutinability first appeared, there was no detectable decrease in i-a or hemolytic c3 activity, and no detectable c3 antigen release from the cells. with prolonged exposure to heated serum in edta, i-a (immune adherence) and hemolytic c3 activity were lost. if this exposure was at 37 degrees ... | 1978 | 98586 |
| gonorrhea detection in posthysterectomy patients. | a retrospective study of women examined at the venereal disease clinic after hysterectomy was made to determine which culture site was most likely to show anogenital neisseria gonorrhoeae infection when the cervix was absent. seventeen of 104 such patients were culture positive for n gonorrhoeae. rates of positivity for our culture sites were as follows: urethral, 17/17 (100%); vaginal, 7/17 (41%); and rectal, 2/17 (12%). | 1978 | 98647 |
| localised insertion of new cell wall in bacillus subtilis. | | 1978 | 98715 |
| [listeria monocytogenes meningitis after renal transplantation. report of a case]. | | 1978 | 98821 |
| experimental spinal cord trauma, ii: blood flow, tissue oxygen, evoked potentials in both paretic and plegic monkeys. | graded clinical motor deficits were produced in a series of rhesus monkeys subjected to experimental spinal cord trauma from a variety of impact loads. an argon washout technique was used to measure spinal cord blood flow; tissue oxygen carbon dioxide, and somatosensory evoked potentials (seps) were also monitored. each animal received a clinical grade and, after a week of study, the spinal cords were removed for histopathological grading. blood flow in paraplegic animals was significantly decre ... | 1978 | 98856 |
| quantitation of particles in the freeze-fractured nuclear membrane after renal ischemia. | changes in the number and sizes of membrane-associated particles have been quantitated in the protoplasmic (p) and exoplasmic (e) fracture faces of the outer membrane of nuclei isolated from the inner cortex following renal ischemia and reflow in the rat. no changes were observed in the inner nuclear membrane. after 20-min ischemia, the number of particles in both fracture faces decreased. with reflow, the total number of particles decreased after both 20- and 60-min ischemia. the partition coef ... | 1978 | 98907 |
| [measurement of the variations of cytoplasmic and nuclear volumes of the absorbing cells of the digestive tube according to the nutritional conditions, in the larva of the common toad (bufo bufo l.)]. | | 1978 | 98945 |
| jaundice and breast-feeding among alaskan eskimo newborns. | the course, incidence, and severity of neonatal jaundice was studied in 95 alaskan eskimo infants. breast-fed infants had higher bilirubin concentrations than bottle-fed babies. both groups experienced high bilirubin levels, similar to those previously reported in navajo and oriental infants but greater than those observed in whites and blacks. a marked capacity to inhibit hepatic glucuronyl transferase was observed in breast-milk specimens but only partly accounted for the bilirubin differences ... | 1978 | 99026 |
| development of leucocytozoon caulleryi in chick embryos infected by biting of culicoides arakawae through shell membrane. | chick embryos were infected with leucocytozoon caulleryi by biting of the midge, culicoides arakawae, through the shell membrane. schizonts of l. caulleryi were detected in the chorioallantoic membrane and most of the internal organs of embryos and of chicks after hatching. the development of schizonts was slower in embryos than in chickens. soluble antigens of l. caulleryi were demonstrated by the precipitation test in the allantoic fluid and blood from the embryos and chicks. no erythrocytic s ... | 1978 | 99671 |
| [cannabis]. | cannabis produces a resin, the psychotropic effects of which are known since the high antiquity. it induces euphoria, a feeling of pleasant dreaminess. nevertheless, psychiatric disturbances such as psychomotor deficiency states or acute oniroïd states were described in heavy users countries. these psychiatric disorders put the accent on the starting or catalysing role of cannabis on the premorbid personality. the experimental studies of cannabis on the premorbid personality. the experimental st ... | 1978 | 100034 |
| uk-18892, a new aminoglycoside: an in vitro study. | uk-18892 is a new aminoglycoside antibiotic, a derivative of kanamycin a structurally related to amikacin. it was found to be active against a wide range of pathogenic bacteria, including many gentamicin-resistant strains. the spectrum and degree of activity of uk-18892 were similar to those of amikacin, and differences were relatively minor. uk-18892 was about twice as active as amikacin against gentamicin-susceptible strains of pseudomonas aeruginosa. both amikacin and uk-18892 were equally ac ... | 1978 | 100050 |
| absence of hydrogen peroxide production by or catalase action in rickettsia prowazeki. | glutamic acid oxidation by rickettsia prowazeki is not accompanied by hydrogen peroxide generation, nor is added hydrogen peroxide degraded, as measured by a manometric technique. | 1978 | 101521 |
| purification and properties of a bacillus subtilis endonuclease specific for apurinic sites in dna. | an endonuclease which hydrolyzes depurinated dna has been purified from extracts of bacillus subtilis cells. the endonuclease is a monomeric protein and has a molecular weight of around 56,000. the enzyme is specific for apurinic sites in double-stranded dna, has a ph optimum at 8.0, and is slightly stimulated with 50 mm nacl but completely inhibited with 500 mm nacl. it requires no divalent cations and is insensitive to edta; it has no associated exonuclease. these properties are very similar t ... | 1978 | 101548 |
| [cadmium in the kidneys of slaughtered animals--hazardous for human health?]. | | 1978 | 101772 |
| [importance of bacteriological examinations for mycobacterium tuberculosis of certain groups of population with increased risk of contracting tuberculosis]. | | 1978 | 101984 |
| single-unit activity in the auditory cortex of monkeys selectively attending left vs. right ear stimuli. | single-unit responses were recorded from the auditory cortex of rhesus monkeys that were performing an auditory selective attention task. acoustic stimuli were presented randomly to either the left or right ear through headphones. in a given block of trials one ear was selected as the ear to be attended, and was indicated by lighting either a left or right response key. the animal's task was to press the lighted key whenever stimuli were presented to the attended ear, but to make no response to ... | 1978 | 103597 |
| oligosaccharides and polysaccharides specifically utilizable by bifidobacteria. | | 1978 | 103638 |
| guinea pig immunoglobulin light chain isotypes. ii. the preferential expression of lambda chain-bearing anti-phenyltrimethylammonium antibodies is associated with restricted variable region expression, but not with any alteration in the proportion of lambda chain constant region isotypes, relative to normal immunoglobulins. | the inbred strain 13 guinea pig expresses at least three isotypes of immunoglobulin (ig) lambda chain. the proportion of these isotypes in normal ig can be estimated by isolating a constant (c) region cyanogen bromide peptide from lambda chains and quantitatively analyzing its component tryptic peptides. anti-phenyltrimethylammonium antibody, when analyzed in this way, was found to contain the same proportion of each lambda chain c region isotype as did normal ig. the specific antibody light (l) ... | 1978 | 103730 |
| effects of age on aortic pressure-diameter and elastic stiffness-stress relationships in unanesthetized sheep. | | 1979 | 104801 |
| effects of local anesthetics on bacterial cells. | the membrane effects of chlorpromazine, nupercain, tetracain, and procain were studied using bacillus cereus, b. megaterium, b. subtilis, and streptococcus faecalis, protoplasts from s. faecalis, and isolated membranes from b. subtilis. chlorpromazin, nupercain, and tetracain produced characteristic micromorphological alterations after treatment for 5 to 30 min at ph 7.0 and 20 degrees c; the membrane staining pattern changed from asymmetric to symmetric, complex mesosome-like structures appeare ... | 1979 | 104970 |
| comparative in vivo nitrogen-15 nuclear magnetic resonance study of the cell wall components of five gram-positive bacteria. | the proton-decoupled 9.12 mhz 15n nmr spectra of 15n-labeled bacillus subtilis, bacillus licheniformis, staphylococcus auresu, streptococcus faecalis, and micrococcus lysodeikticus intact cells, isolated cells walls, and cell wall digests have been examined. the general characteristics of gram-positive bacteria 15n nmr spectra and described and spectral assignments are provided, which allow in vivo 15n nmr to be applied to a wide range of problems in bacterial cell wall research. the qualitative ... | 1979 | 105756 |
| membrane changes during growth of tetrahymena in the presence of ethanol. | after a brief lag period for acclimation, tetrahymena pyriformis, strain nt-1, is capable of growing in culture medium containing high levels of ethanol. when grown in a medium having 1.6% ethanol, the membrane phospholipid composition was significantly different from that of control cells. the principal changes included a reduction in hexadecenoic acids (16 : 1 and 16 : 2) from 23% to 5% and an increase in linoleic acid (18 : 2) from 14% to 25% similar but less pronounced changes were observed ... | 1979 | 105757 |
| effect of sulfonylurea treatment and fasting on the levels of plasma amino acids in the rat. | | 1978 | 105980 |
| percutaneous nitroglycerin absorption in rats. | percutaneous nitroglycerin absorption was studied in shaved rats by monitoring unchanged plasma drug concentrations for up to 4 hr. drug absorption from the neat liquid state or from an alcoholic solution was considerably poorer than that from a commercial ointment. this observation was unanticipated since the driving force for percutaneous drug absorption was assumed to be drug thermodynamics. potential artifacts such as drug volatilization from the skin, reduction of surface area through dropl ... | 1979 | 107313 |
| [semiessential and nonessential amino acids in parenteral feeding]. | with reference to a critical study of the relevant literature and to results from their own investigations, the authors emphasize the importance of the semi-essential and non-essential amino acids arginine, histidine, tyrosine, cystine and glutamic acid for the completion of essential amino-acid mixtures destined for parenteral feeding. madden's assumption that intravenously applied glutamic acid is intolerable was not supported by the authors' experiments in dogs. as evidenced by the increase o ... | 1978 | 107453 |
| the viability of cryopreserved aegyptianella pullorum carpano, 1928 in the vector argas (persicargas) walkerae kaiser and hoogstraal, 1969. | | 1979 | 107668 |
| constant and flickering light stimulations produce similar effects on rna content in visual cells. | adult male rats were illuminated for 2 h with a constant or flickering light of 40 lx intensity; frequency of flickering was 2 hz. by means of two-wave-length visible cytospectrophotometry of gallocyanin-stained sections, it was shown that the light stimulation resulted in a marked rna accumulation in retina ganglion neurons and in the neurons of all the cell layers of visual cortex (with the only exception of the layer vi). in the cells of perineuronal glia, a decrease of the rna content per ce ... | 1978 | 107713 |
| an artificial 'haemophilic' plasma for one-stage factor-viii assay. | an 'artificial' plasma for one-stage factor-viii assays is made by incubating human plasma with edta, to destroy factor viii, and afterwards removing the anticoagulant by dialysis. bovine factor v is then added to a given level. in the assay, contact activation is controlled by adding contact product. it was confirmed that factor-viii activity was destroyed and that the edta was freely dialysable. the fibrinogen in the treated plasma clotted normally with thrombin. likely variation in the factor ... | 1978 | 107960 |
| enzymes involved in the degradation of thyrotropin releasing hormone (trh) and luteinizing hormone releasing hormone (lh-rh) in bovine brain. | as part of an investigation of neuropeptide inactivation mechanisms, we have resolved an enzymatic activity in bovine brain which catalyzes the deamidation of thyrotropin releasing hormone (trh) and the hydrolysis of the pro9--gly10--nh2 bond of luteinizing hormone releasing hormone (lh-rh) from a second lh-rh degrading activity which does not degrade trh. the former activity is similar, if not identical to, the post-proline cleaving enzyme in kidney as it is active toward the post-proline cleav ... | 1979 | 107998 |
| [evidence of similar anti-b4 idiotypes in a3+ phenotype rabbits immunized against the b4 allotype]. | | 1979 | 108029 |
| macaca assamensis as a new host for experimental plasmodium knowlesi infection. | | 1978 | 108217 |
| [investigations on the aminoglycoside inactivating enzyme aac-(6') iv (author's transl)]. | in serratia marcescens and pseudomonas aeruginosa from clinical specimen acetyltransferase aac-(6') iv leads to varying phaenotypically expressed resistance to aminoglycoside antibiotics. the substrate profile and the rate of inactivation of the enzymes investigated are almost identical with each other and with the enzyme of p. aeruginosa gn 315. the enzymes cannot be associated with r factors by the standard methods for conjugation, transformation, density gradient centrifugation and agarose g ... | 1979 | 108221 |
| properties of the bacillus subtilis spore coat. | about 70% of the protein in isolated bacillus subtilis spore coats was solubilized by treatment with a combination of reducing and denaturing agents at alkaline ph. the residue, consisting primarily of protein, was insoluble in a variety of reagents. the soluble proteins were resolved into at least seven bands by sodium dodecyl sulfate gel electrophoresis. about one-half of the total was four proteins of 8,000 to 12,000 daltons. these were relatively tyrosine rich, and one was a glycoprotein. th ... | 1979 | 108242 |
| interconversion between multiple glucose 6-phosphate-dependent forms of glycogen synthase in intact adipose tissue. | we have tested the hypothesis that interconversion between multiple glucose-6-p-dependent forms of glycogen synthase helps regulate glycogen synthesis in adipose tissue. our results indicate that interconversion of glycogen synthase in adipose tissue involves primarily dependent forms and that these interconversions were measured better by monitoring the activation constant (a0.5) for glucose-6-p than measuring the -: + glucose-6-p activity ratio. insulin decreased and epinephrine increased the ... | 1979 | 108279 |
| transformation of pseudomonas aeruginosa and escherichia coli with resistance plasmid dna: formation of smaller conjugative plasmids from rpi. | sheared dna from rpi, and r plasmid from a strain of pseudomonas aeruginosa, was used to transform other strains of p. aeruginosa and escherichia coli. from transformed cells other plasmids like rpi were isolated. these deletion plasmids were conjugally transferrable and confer resistance mainly against carbenicillin and tetracycline. | 1979 | 108516 |