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immunoregulatory gene polymorphisms in japanese women with preterm births and periodontitis.many studies have reported an association between periodontal disease and preterm birth, although this remains controversial. cytokines and antibodies produced to give resistance to infection can enter the bloodstream and cause preterm labor. we analyzed maternal genetic polymorphisms in various immunoregulatory genes that could affect both preterm birth and periodontitis. a total of 1099 women referred to the department of obstetrics and gynecology, niigata university medical and dental hospita ...201222382006
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