| cytotoxicity of coffee in human intestinal cells in vitro and its inhibition by peroxidase. | the cytotoxic effects of dried preparations of nine different beverages, including alcoholic drinks, on human embryonic intestinal cells in vitro and the cytoprotective effects of several enzymes were examined. instant coffee and green tea were the most cytotoxic beverages (id(50) value 0.016 ml equivalents/ml). peroxidase (0.015 units/ml) completely nullified the cytotoxic effects of instant coffee, green tea and black tea; catalase had a less protective effect. in contrast, superoxide dismutas ... | 1992 | 20732140 |
| effect of different doses of un-fractionated green & black tea extracts on thyroid physiology. | tea is a rich source of polyphenolic flavonoids including catechins, which are thought to contribute to the health benefits of it. flavonoids have been reported to have antithyroid and goitrogenic effect. the purpose of this study was to evaluate whether high doses of green and black tea have a harmful effect on thyroid physiology. un-fractionated green and black tea extracts were administered orally to male rats for 30 days at doses of 1.25 g%, 2.5 g% and 5.0 g%. the results showed that green t ... | 2010 | 20801949 |
| genoprotective effects of green tea (camellia sinensis) in human subjects: results of a controlled supplementation trial. | green tea is rich in polyphenolic antioxidants and has widely reported but largely unsubstantiated health benefits. in the present study, genoprotective effects of two types of green tea were studied both in an in vitro and in a human supplementation trial. for the in vitro study, human lymphocytes were pre-incubated in tea (0·005-0·1 %, w/v), washed and subjected to oxidant challenge induced by h2o2. in a placebo-controlled, cross-over supplementation study, eighteen healthy volunteers took 2 x ... | 2011 | 20807462 |
| why the xanthine derivatives are used to study of p-glycoprotein-mediated multidrug resistance in l1210/vcr line cells. | there is generally well known that various xanthines occur frequently in natural products, e.g. black coffee, black tea, green tea, natural dyes etc. xanthine molecules are good tolerated and metabolised by organisms. moreover, natural xanthines and/or sythesized xanthines may recall a lot positive affects (hemorheologic properties, anti-inflammatory properties, tracheal smooth muscle relaxant, positive chronotropic and central nervous system-stimulating, etc.) and may even induce a quantity of ... | 2010 | 20817945 |
| intrinsic apoptosis and nf-κb signaling are potential molecular targets for chemoprevention by black tea polyphenols in hepg2 cells in vitro and in a rat hepatocarcinogenesis model in vivo. | antiproliferative and apoptosis inducing effects of black tea polyphenols (polyphenon-b) on hepg2 cells in vitro and in a rat hepatocarcinogenesis model in vivo were investigated. viability of hepg2 cells was evaluated by the mtt assay, and apoptosis by ao-eb and dapi staining, cell cycle analysis, and annexin v-pi assay. for the in vivo study, male sprague-dawley rats treated with dimethylaminoazobenzene (dab) (0.06%) were used. the expression of bcl-2 and nf-κb family members were analyzed by ... | 2010 | 20828598 |
| outcomes of 3% green tea emulsion on skin sebum production in male volunteers. | this study was aimed to depict potential effects of stable formulation (water in oil emulsion), containing 3% green tea (camellia sinensis l) extract on skin sebum production in healthy human volunteers. for this purpose formulation was designed using 3% ethanolic green tea extract and abil®em90 was used as an emulsifier. formulation was applied to the cheeks of healthy human volunteers (n=10) for a period of 8 weeks. measurements for skin sebum production were considered using sebumeter mpa 5. ... | 2010 | 20846135 |
| the efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review. | this review focuses on the efficacy and safety of effective herbal medicines in the management of hyperlipidemia in human. | 2010 | 20858178 |
| restoration of cardiomyocyte function in streptozotocin-induced diabetic rats after treatment with vanadate in a tea decoction. | diabetes mellitus is associated with abnormal cardiomyocyte ca(2+) transients and contractile performance. we investigated the possibility that an alteration in inositol trisphosphate/phospholipase c (ip₃/plc) signalling may be involved in this dysfunction. phosphatidic acid stimulates cardiomyocyte contraction through an ip₃/plc signaling cascade. we also tested a novel therapeutic intervention to assess its efficacy in reversing any potential defects. diabetes was induced in sprague-dawley rat ... | 2010 | 20874687 |
| phenolic content and in vitro inhibitory effects on oxidation and protein glycation of some thai medicinal plants. | fifteen medicinal plant extracts were investigated for: total phenolic content and free radical scavenging effect by dpph and abts assays; anti-lipid peroxidation activity by tbars; and for antiglycation activity. the results revealed that the total phenolic content showed good correlation with free radical scavenging by abts (r = 0.721) and anti-lipid peroxidation by tbars (r = -0.659), but showed no correlation with antiglycation. three extracts from tamarindus indica, camellia sinensis and ar ... | 2010 | 20884454 |
| evaluation of the anxiolytic activity of nr-anx-c (a polyherbal formulation) in ethanol withdrawal-induced anxiety behavior in rats. | the present study investigates the anxiolytic activity of nr-anx-c, a standardized polyherbal formulation containing the extracts of withania somnifera, ocimum sanctum, camellia sinensis, triphala, and shilajit in ethanol withdrawal- (ew-) induced anxiety behavior in rats. ethanol dependence in rats was produced by substitution of drinking water with 7.5% v/v alcohol for 10 days. then, ethanol withdrawal was induced by replacing alcohol with drinking water, 12 hours prior to experimentation. aft ... | 2010 | 20953426 |
| black tea and theaflavins assist healing of indomethacin-induced gastric ulceration in mice by antioxidative action. | the healing activities of black tea (bt) and the theaflavins (tf) against the indomethacin-induced stomach ulceration were studied in a mouse model. indomethacin (18 mg/kg, p.o.) administration induced maximum ulceration in the glandular portion of the gastric mucosa on the 3rd day, accompanied by increased lipid peroxidation and protein oxidation, depletion of thiol-defense and mucin, as well as reduced expressions of cyclooxygenases (cox) and prostaglandin (pg) e synthesis in the gastric tissu ... | 2010 | 20953434 |
| black and green tea improves lipid profile and lipid peroxidation parameters in wistar rats fed a high-cholesterol diet. | in the present study, the efficacy of black tea (bt) and green tea (gt) was studied in relation to serum and hepatic oxidative abnormalities in hypercholesterolemic rats. hypercholesterolemia was induced in male wistar rats (8 week old) by feeding them with a high-cholesterol diet (hcd) for 35 days. the experimental rats were given bt and gt as a supplement (7 g/l) via drinking water. increased hepatic and serum lipid profile along with abnormalities in oxidative marker, with a concomitant incre ... | 2010 | 20960086 |
| differential expression pattern of an acidic 9/13-lipoxygenase in flower opening and senescence and in leaf response to phloem feeders in the tea plant. | lipoxygenase (loxs) is a large family of plant enzymes that catalyse the hydroperoxidation of free polyunsaturated fatty acids into diverse biologically active compounds, collectively named phyto-oxylipins. although multiple isoforms of loxs have been identified in a wide range of annual herbaceous plants, the genes encoding these enzymes in perennial woody plants have not received as much attention. in camellia sinensis (l.) o. kuntze, no lox gene of any type has been isolated, and its possible ... | 2010 | 20969806 |
| safety evaluation of tea (camellia sinensis (l.) o. kuntze) flower extract: assessment of mutagenicity, and acute and subchronic toxicity in rats. | tea (camellia sinensis (l.) o. kuntze, theaceae) flowers possess many physiological functions and have been used in traditional medicines for deodorization, skin care, cough suppressant and expectorant in china. however, there is a little information about its possible toxicity. | 2010 | 21034804 |
| black tea reduces diarrhoea prevalence but decreases growth performance in enterotoxigenic escherichia coli-infected post-weaning piglets. | enterotoxigenic escherichia coli (etec) is a main cause of diarrhoea in humans and piglets. in vitro, black tea extract (bte) has anti-pathogenic properties. anti-diarrhoeal properties of bte were assessed in a pig model of gastrointestinal infection. at weaning (day 0), piglets (n = 96) were randomly assigned to a diet containing 0% (control), 0.4% or 0.8% (wt/wt) bte during 27 days. piglets were orally infected with 6.4 × 10(6) cfu of etec on day 6. faecal consistency, feed intake and body wei ... | 2010 | 21039929 |
| oolong tea theasinensins attenuate cyclooxygenase-2 expression in lipopolysaccharide (lps)-activated mouse macrophages: structure-activity relationship and molecular mechanisms. | oolong tea theasinensins are a group of tea polyphenols different from green tea catechins and black tea theaflavins. the present study reports the inhibitory effects of oolong tea theasinensins on the expression of cyclooxygenase-2 (cox-2) and underlying molecular mechanisms in lipopolysaccharide (lps)-activated murine macrophage raw264 cells. the structure-activity data revealed that the galloyl moiety of theasinensins played an important role in the inhibitory actions. theasinensin a, a more ... | 2010 | 21082860 |
| green tea extract-induced lethal toxicity in fasted but not in nonfasted dogs. | recent chronic toxicity studies performed on green tea extracts in fasted dogs have revealed some unique dose-limiting lethal liver, gastrointestinal, and renal toxicities. key findings included necrosis of hepatic cells, gastrointestinal epithelia and renal tubules, atrophy of reproductive organs, atrophy and necrosis of hematopoietic tissues, and associated hematological changes. the polyphenol cachetins (a mixture of primarily epigallocatechin gallate [≥55%]; plus up to 10% each of epigalloca ... | 2010 | 21098339 |
| green and black tea suppress hyperglycemia and insulin resistance by retaining the expression of glucose transporter 4 in muscle of high-fat diet-fed c57bl/6j mice. | to investigate the preventive effects of tea on hyperglycemia and insulin resistance, male c57bl/6j mice were given a high-fat diet containing 29% lard and also green or black tea ad libitum for 14 weeks. both teas suppressed body weight gain and deposition of white adipose tissue caused by the diet. in addition, they improved hyperglycemia and glucose intolerance by stimulating glucose uptake activity accompanied by the translocation of glucose transporter (glut) 4 to the plasma membrane in mus ... | 2010 | 21105694 |
| pu-erh black tea supplementation decreases quinocetone-induced ros generation and oxidative dna damage in balb/c mice. | quinocetone (3-methyl-2-quinoxalinbenzenevinylketo-1,4-dioxide, qct), a new feed antibacterial agent of quinoxaline-1,4-dioxides family, has been used as an animal growth promoter. however, few data about its potential toxicity in vivo were available. in this study, genotoxicity of qct and the relationship with oxidative stress were investigated. balb/c mice with both sexes were administrated with qct (12000, 6000 and 3000 mg/kg/bw, respectively) by gavage acutely. dna damage, generation of reac ... | 2010 | 21112366 |
| oral diuretic activity of hot water infusion of sri lankan black tea (camellia sinensis l.) in rats. | black tea [camellia sinensis (l.) o. kuntze (family: theaceae)] has been used by sri lankan traditional practitioners to promote diuresis. however, the type and grade of tea is not specified. | 2010 | 21120027 |
| proteomic profiling and redox status alteration of recalcitrant tea (camellia sinensis) seed in response to desiccation. | tea seed is believed to be recalcitrant based on its sensitivity to chilling or drying stress. reactive oxygen species (ros) and alterations in cytosolic redox status have been implicated in intolerance to desiccation by recalcitrant seed, but there is little information available regarding how ros are regulated in seeds susceptible to drying stress. we investigated changes in protein expression and activity in tea embryo in response to desiccation using physiological and proteomic methods. resu ... | 2010 | 21120520 |
| acute and subchronic oral toxicities of pu-erh black tea extract in sprague-dawley rats. | pu-erh black tea, which is obtained by first parching crude green tea leaves and then undergoes secondary fermentation with microorganisms, has been believed to be beneficial beverages for health for nearly 2000 years in china, japan and taiwan area. but its potential toxicity when administered at a high dose as concentrated extracts has not been completely investigated. | 2010 | 21134434 |
| effect on the epigallocatechin gallate/epigallocatechin ratio in a green tea (camellia sinensis l.) extract of different extraction temperatures and its effect on iga production in mice. | we found that the epigallocatechin gallate (egcg)/epigallocatechin (egc) ratio in a green tea (camellia sinensis l.) extract was affected by the extraction temperature. the egcg/egc ratio in the 4 °c extract was around 1:3-4, whereas in the 100 °c extract, it was around 1:0.7. oral administration of the mixture with a high egc ratio (1:2-3 = egcg/egc) resulted in greater iga production by murine peyer's patch cells. | 2010 | 21150115 |
| cacl2 improves post-drought recovery potential in camellia sinensis (l) o. kuntze. | drought stress affects the growth and productivity of the tea plant. however, the damage caused is not permanent. the present investigation studies the effect of cacl(2) on antioxidative responses of tea during post-drought recovery. increase in dry mass, proline and phenolic content of leaf with decrease in h(2)o(2) and lipid peroxidation and increased activities of enzymes such as sod, cat, pox and gr in response to increased foliar cacl(2) concentration are indications for the recovery of str ... | 2010 | 21153899 |
| agrobacterium-mediated silencing of caffeine synthesis through root transformation in camellia sinensis l. | tea [camellia sinensis (l.) o. kuntze] is a perennial and most popular non-alcoholic caffeine-containing beverage crop. tea has several constraints for its genetic improvement such as its high polyphenolic content and woody perennial nature. the development of transgenic tea is very difficult, laborious, and time taking process. in tea, regeneration requires minimum 8-12 months. in view of this, attempt has been made in this article to develop a rapid, efficient, and quite economical agrobacteri ... | 2010 | 21181507 |
| in vitro protective effects of colon-available extract of camellia sinensis (tea) against hydrogen peroxide and beta-amyloid (aβ((1-42))) induced cytotoxicity in differentiated pc12 cells. | there is mounting evidence that the deposition and aggregation of β-amyloid peptides (aβ) in the brain play a significant role in the development and pathogenesis of alzheimer's disease. there is further evidence that free radical species such as hydrogen peroxide (h(2)o(2)) mediate aβ induced toxicity. previous studies have demonstrated that green tea polyphenols possess neuroprotective properties through their ability to ameliorate oxidative stress induced by free radical species. green tea po ... | 2010 | 21183323 |
| black tea polyphenol theaflavin suppresses lps-induced icam-1 and vcam-1 expression via blockage of nf-κb and jnk activation in intestinal epithelial cells. | the aim of this study was to determine the impact of the black tea polyphenol, theaflavin, on the expression of adhesion molecules and activation of lipopolysaccharide (lps)-induced innate signaling in rat intestinal epithelial (rie) cells. | 2010 | 21184129 |
| laboratory studies on weight control and prevention of metabolic syndrome by green tea. | green tea (camellia sinensis, theaceace) is the second most popular beverage in the world and has been extensively studied for its putative disease preventive effects. green tea is characterized by the presence of a high concentrations of polyphenolic compounds known as catechins, with (-)-epigallocatechin-3-gallate (egcg) being the most abundant and most well-studied. metabolic syndrome (mets) is a complex condition that is defined by the presence of elevated waist circumference, dysglycemia, e ... | 2010 | 21193040 |
| effects of ocimum sanctum and camellia sinensis on stress-induced anxiety and depression in male albino rattus norvegicus. | the aim of this study was to study the ameliorative effects of ocimum sanctum and camellia sinensis on stress-induced anxiety and depression. | 2010 | 21206619 |
| effect of green tea powder (camellia sinensis l. cv. benifuuki) particle size on o-methylated egcg absorption in rats; the kakegawa study. | tea polyphenols, e.g., (-)-epigallocatechin-3-o-(3-o-methyl gallate (egcg3"me), (-)-epigallocatechin-3-o-gallate (egcg), (-)-epigallocatechin (egc), (-)-epicatechin-3-o-gallate (ecg), and (-)-epicatechin (ec), are believed to be responsible for the beneficial effects of tea. 'benifuuki', a tea (camellia sinensis l.) cultivar grown in japan, is rich in the anti-allergic molecule epigallocatechin-3-o-(3-o-methyl) gallate (egcg3"me). pulverized benifuuki green tea powder (bgp) is more widely distri ... | 2011 | 21207145 |
| plasma pharmacokinetics of catechin metabolite 4'-o-me-egc in healthy humans. | background: tea is an infusion of the leaves of the camellia sinensis plant and is the most widely consumed beverage in the world after water. green tea contains significant amounts of polyphenol catechins and represents a promising dietary component to maintain health and well-being. epidemiological studies indicate that polyphenol intake may have potential health benefits, such as, reducing the incidence of coronary heart disease, diabetes and cancer. while bioavailability of green tea bioacti ... | 2011 | 21212969 |
| increased plasma concentration of epigallocatechin in mice after orally administering a green tea (camellia sinensis l.) extract supplemented by steamed rice. | we attempted to improve the bioavailability of green tea catechins by using food ingredients. the catechin bioavailability of a green tea extract administered to mice was significantly (p<0.05) increased by supplementing with steamed rice. this enhanced bioavailability was due to the increased concentration of plasma non-gallated catechins, especially epigallocatechin (egc). | 2011 | 21228465 |
| sterilization and protection of protein in combinations of camellia sinensis green tea extract and gamma irradiation. | sterilization of milk protein without heating is of great interest. gamma irradiation is a very powerful method to decontaminated casein. gamma-irradiation of proteins in aqueous media at doses higher than 5kgy is known to induce their aggregation (without oxygen) or degradation (in presence of oxygen). camellia sinensis green tea extract addition before irradiation of caseins cow milk proteins was examined. it was found that the presence of c. sinensis green tea extract during irradiation in th ... | 2011 | 21238480 |
| black tea polyphenol inhibits cxcl10 production in oncostatin m-stimulated human gingival fibroblasts. | cxc chemokine ligand 10 (cxcl10) plays an important role in the infiltration of th1 cells and thus in the exacerbation of periodontal disease. theaflavin-3,3'-digallate (tfdg), polyphenol in black tea, has some beneficial effects but the effect of tfdg on cxcl10 production from human gingival fibroblasts (hgfs) is uncertain. in this study, we investigated the mechanisms by which tfdg may inhibit oncostatin m (osm)-induced cxcl10 production in human gingival fibroblasts. tfdg prevented osm-mediat ... | 2011 | 21255696 |
| white tea (camellia sinensis kuntze) exerts neuroprotection against hydrogen peroxide-induced toxicity in pc12 cells. | tea is a popular beverage whose consumption is associated with prevention of certain disorders. the objective of the study was to investigate the potential neuroprotective effect of white tea extract (wte) on hydrogen peroxide induced toxicity in pc12 cells. cells were treated with various doses of wte (10-250 µg/ml) before exposition to 250 µm hydrogen peroxide and cell survival was determined through the mtt and ldh assays. oxidative stress was quantified in the cells after treatments as intra ... | 2011 | 21271291 |
| interactions of green tea catechins with organic anion-transporting polypeptides. | organic anion-transporting polypeptides (oatps) are multispecific transporters that mediate the uptake of numerous drugs and xenobiotics into cells. here, we examined the effect of green tea (camellia sinensis) catechins on the function of the four oatps expressed in human enterocytes and hepatocytes. uptake of the model substrate estrone-3-sulfate by cells expressing oatp1a2, oatp1b1, oatp1b3, or oatp2b1 was measured in the absence and presence of the four most abundant flavonols found in green ... | 2011 | 21278283 |
| diverse inhibition of plasminogen activator inhibitor type 1 by theaflavins of black tea. | fruits, vegetables, spices and a variety of teas are suggested for the prevention of many diseases. they encompass active, non-nutritional ingredients called nutraceuticals which are defined as food products that provide health benefits. many nutraceuticals have been tested to identify inhibitors of plasminogen activator inhibitor (pai-1). pai-1 is the major and fast acting physiological inhibitor of fibrinolysis. however, preclinical studies of pai-1 inhibitors have revealed an additional role ... | 2011 | 21308350 |
| new phenolic compounds from camellia sinensis l. leaves fermented with aspergillus sp. | two new phenolic compounds, teadenol a (1) and teadenol b (2), were isolated from tea (camellia sinensis l.) leaves fermented with aspergillus sp. (pk-1, farm ap-21280). the chemical structures of 1 and 2 were elucidated based on the analyses of their spectroscopic data. the absolute configurations of the structures of 1 and 2 were also certified by their biosynthetic preparation in the treatment of tea catechins with aspergillus sp. | 2011 | 21327519 |
| age-dependent changes in the proteolytic-antiproteolytic balance after alcohol and black tea consumption. | aging is accompanied by changes in the redox balance that is additionally modified by alcohol. ethanol metabolism is connected with generation of free radicals which can damage cell components especially when antioxidant mechanisms are not able to neutralize them. in connection with the necessity of prevention against oxidative consequences, natural antioxidants are looked for. a natural and commonly used component of the diets with antioxidant properties are teas, especially the black tea. this ... | 2011 | 21329467 |
| a nonstaining and tasteless hydrophobic salt of chlorhexidine. | chlorhexidine (chx) remains one of the most effective and widely used antiplaque agents around the world, although its side effects still limit a long-term usage as the patient compliance for oral treatment with chx. we hypothesize that a less water-soluble tetracation salt of chx might be able to interact weakly with tooth enamel and oral taste cells, reducing those undesirable side effects of chx. the chlorhexidine tetrapalmitate (chxtp) was obtained and the antimicrobial activity was evaluate ... | 2011 | 21344413 |
| evaluation of the antioxidant properties of fruit and flavoured black teas. | objective: antioxidant properties of the water extracts of the commercial bagged fruit and flavoured black teas were evaluated and compared with typical black teas of c. sinensis. methods: folin-ciocalteu (fc) assay, cupric ion reducing antioxidant capacity (cuprac) and dpph radical method were used for these purposes. the content of selected flavonoids and phenolic acids was also determined by high-performance liquid chromatography with tandem mass spectrometry in the negative electrospray ioni ... | 2011 | 21360165 |
| understanding the broad-spectrum neuroprotective action profile of green tea polyphenols in aging and neurodegenerative diseases. | during the last century, the world population has shown a staggering increase in its proportion of elderly members and thus, neurodegenerative diseases like alzheimer's and parkinson's diseases (ad and pd, respectively) are becoming an increasing burden. brain aging and neurodegenerative diseases of the elderly are characterized by oxidative damage, dysregulation of redox metals homeostasis and inflammation, supporting a therapeutic use of antioxidants. natural plant polyphenols (flavonoids and ... | 2011 | 21368374 |
| tea contains potent inhibitors of tyrosine phosphatase ptp1b. | tea is widely consumed all over the world. studies have demonstrated the role of tea in prevention and treatment of various chronic diseases including diabetes and obesity, but the underlying mechanism is unclear. ptp1b is a widely expressed tyrosine phosphatase which has been defined as a target for therapeutic drug development to treat diabetes and obesity. in screening for inhibitors of ptp1b, we found that aqueous extracts of teas exhibited potent ptp1b inhibitory effects with an ic50 value ... | 2011 | 21371422 |
| egcg stimulates autophagy and reduces cytoplasmic hmgb1 levels in endotoxin-stimulated macrophages. | historically, consumption of green tea (camellia sinensis) has been associated with health benefits against multiple diseases including cancer, atherosclerosis and cardiovascular disorders. emerging evidence has suggested a pathogenic role for hmgb1, a newly identified "late" mediator of lethal systemic inflammation, in the aforementioned diseases. here we demonstrated that a major ingredient of green tea, egcg, was internalized into hmgb1-containing lc3-positive cytoplasmic vesicles (likely aut ... | 2011 | 21371444 |
| oral hypoglycaemic, antihyperglycaemic and antidiabetic activities of sri lankan broken orange pekoe fannings (bopf) grade black tea (camellia sinensis l.) in rats. | ethnopharmcological relevance: sri lankan traditional practitioners recommend the consumption of black tea infusion (bti) made from camellia sinensis l. plant for regulation of glycaemia. however, they do not specify the grade of tea and their origin (i.e., agroclimatic elevation) and as such many prediabetics and milddiabetics use bopf grade tea. | 2011 | 21397000 |
| [adsorption kinetic study of the interaction between human salivary alpha-amylase and the polyphenoles from the black/green tea]. | to explore the driving force of the oral astringency produced by the interaction of theaflavin (tf) and epigallocatechin-3-gallate (egcg) to human salivary a-amylase(hsa). | 2011 | 21427890 |
| the impact of packaging materials on the antioxidant phytochemical stability of aqueous infusions of green tea (camellia sinensis) and yaupon holly (ilex vomitoria) during cold storage. | ready to drink (rtd) teas are a growing segment in the beverage category, brought about by improvements in the flavor of these products and healthy market trends driven by consumers. the presented results evaluated the antioxidant phytochemical stability of rtd teas from aqueous infusions of traditional green tea (camellia sinensis) and a botanical tea from yaupon holly (ilex vomitoria) as influenced by packaging materials during cold storage. two common packaging materials for rtd products are ... | 2011 | 21434687 |
| [using green and black tea extracts to prevent toxic effects of acetone]. | the authors demonstrated use of water-alcohol extracts of green and black tea for possible prevention of carbohydrates and lipid metabolism disorders in rats liver due to acetone intoxication. polyphenols obtained from tea and injected into the animals before acetone intoxication resulted in preserved serum glucose level, phospholipid and neutral lipid contents, lower levels of cholesterol, triacylglycerines, saturated fatty acids in liver. | 2010 | 21446066 |
| black tea is not significantly different from water in the maintenance of normal hydration in human subjects: results from a randomised controlled trial. | there is a belief that caffeinated drinks, such as tea, may adversely affect hydration. this was investigated in a randomised controlled trial. healthy resting males (n 21) were recruited from the general population. following 24 h of abstention from caffeine, alcohol and vigorous physical activity, including a 10 h overnight fast, all men underwent four separate test days in a counter-balanced order with a 5 d washout in between. the test beverages, provided at regular intervals, were 4 × 240 m ... | 2011 | 21450118 |
| black tea prevents high fat diet-induced non-alcoholic steatohepatitis. | the chemoprotective actions of aqueous black tea extract (bte) against high-fat diet (hfd) (60%)-induced non-alcoholic steatohepatitis (nash) were examined in wistar rats of both sexes. the results indicated that the hfd rats had higher concentrations of serum glucose, cholesterol, triglycerides, low-density lipoprotein, very low-density lipoprotein, high-density lipoprotein and bilirubin than the corresponding control rats. the enzymes serum aspartate aminotransferase and alanine aminotransfera ... | 2011 | 21452373 |
| theaflavins extracted from black tea inhibit airway mucous hypersecretion induced by cigarette smoke in rats. | theaflavins isolated from black tea have been used in studies on the prevention of tumor growth. the aim of this study was to investigate whether treatment with theaflavins influences the mucus hypersecretion induced by cigarette smoke in the lungs of experimental rats. firstly, cigarette smoke was aerosolized using a machine designed for inhalation by rats. the rats were divided into the negative control group, the cigarette smoke inhalation group, the theaflavins (tfs) treatment group, and the ... | 2011 | 21475988 |
| iron(iii) reducing and antiradical activities of three sideritis from turkey. | context: sideritis species (lamiaceae) are widely used as herbal tea and have been used in folk medicine for their anti-inflammatory, anti-rheumatic, digestive, and antimicrobial activities in turkey. sideritis dichotoma huter., sideritis erythrantha boiss. var. cedrotorum, and sideritis vuralii h. duman et başer are available as commercial products in turkey. objective: the antiradical activities of the various solvent extracts of sideritis species are investigated here for the first time. mate ... | 2011 | 21500963 |
| the inhibition of the mammalian dna methyltransferase 3a (dnmt3a) by dietary black tea and coffee polyphenols. | abstract: | 2011 | 21510884 |
| chemopreventive effects of tea in prostate cancer: green tea versus black tea. | the polyphenol compositions of green tea (gt) and black tea (bt) are very different due to post-harvest processing. gt contains higher concentrations of monomeric polyphenols, which affect numerous intracellular signaling pathways involved in prostate cancer (cap) development. bt polymers, on the other hand, are poorly absorbed and are converted to phenolic acids by the colonic microflora. therefore, after consumption of gt, higher concentrations of polyphenols are found in the circulation, wher ... | 2011 | 21538852 |
| mechanistic issues concerning cancer prevention by tea catechins. | the cancer preventive activities of tea (camellia sinensis, theaceae) have been demonstrated in animal models for cancers at different organ sites and suggested by some epidemiological studies. many mechanisms for cancer prevention have been proposed based on studies in cell lines, which demonstrated the modulation of signal transduction and metabolic pathways by (-)-epigallocatechin-3-gallate (egcg), the most abundant and active polyphenol in green tea. these molecular events may result in cell ... | 2011 | 21538856 |
| modulating effects of rooibos and honeybush herbal teas on the development of esophageal papillomas in rats. | widespread consumption of herbal teas has stimulated interest in their role as cancer preventive agents. the present investigation monitored the modulation of methylbenzylnitrosamine (mbn)-induced esophageal squamous cell carcinogenesis by rooibos (aspalathus linearis) and honeybush (cyclopia intermedia) herbal and camellia sinensis teas in male f344 rats. the tumor multiplicity was significantly (p < 0.05) inhibited by unfermented honeybush (45.5%), green (50%), and black (36%) teas, while the ... | 2011 | 21541901 |
| the inhibitory effect of camellia sinensis extracts against the neuromuscular blockade of crotalus durissus terrificus venom. | in geographically isolated populations where intensive medical care or serum therapy is not easily accessible snake envenomation is a major cause for concern. the aim of the present study was to test camellia sinensis extracts, theaflavin and epigallocatechin (two of the main c. sinensis components) against the irreversible neuromuscular blockade induced by crotalus durissus terrificus venom in mouse phrenic-nerve diaphragm preparations. a quantitative histological study was also performed. the ... | 2010 | 21544176 |
| black tea and theaflavins suppress various inflammatory modulators and i-nos mediated nitric oxide synthesis during gastric ulcer healing. | abstract the modulation of the cyclooxygenase-independent pathway by black tea (bt) and its constituent theaflavins (tfs) during their healing action against indomethacin-induced stomach ulceration in mice was investigated. on the 3(rd) day of its administration, indomethacin (18 mg/kg) induced maximum stomach ulceration, which was associated with increased myeloperoxidase (mpo) activity (93.3%, p < 0.001), and inducible nitric oxide synthase (inos) expression (1.6-fold, p < 0.001), along with a ... | 2011 | 21545263 |
| green tea extract ameliorates reperfusion injury to rat livers after warm ischemia in a dose-dependent manner. | scope: polyphenolic constituents of green tea (camellia sinensis) have been shown to be potent scavengers of reactive oxygen species (ros). thus, this study was designed to assess its effects after liver ischemia-reperfusion. methods and results: fasted sprague-dawley rats were gavaged with different concentrations of green tea extract (gte) 2 h before 90 min of warm ischemia of the left lateral liver lobe (30% of liver). controls were given the same volume of ringer's solution. a preparation of ... | 2011 | 21595017 |
| green and black tea in relation to gynecologic cancers. | scope: observational studies have evaluated the relationship between green tea intake and cancers of the ovary and endometrium, but we are not aware of the published studies on green tea intake and risk of human papillomavirus (hpv)-related cancers of the cervix, vagina, or vulva. methods and results: a critical review of the published literature on tea intake and risk of ovarian and endometrial cancers was conducted. in meta-analyses, we report inverse associations for green tea intake and risk ... | 2011 | 21595018 |
| oxidative stress and antioxidant status in intensely exercising horses administered nutraceutical extracts. | many nutraceuticals are used as equine supplements without their efficacy having been scientifically tested. black tea, cranberries, orange peel and ginger are a few of those nutraceuticals that warrant further study. | 2010 | 21059024 |
| tea in chemoprevention of cancer. | this review summarizes available information on epidemiological and experimental data showing an association of tea consumption with cancer prevention. studies showing cancer risk associated with tea consumption are also summarized. tea is grown in about 30 countries and, next to water, is the most widely consumed beverage in the world. experimental studies demonstrating the chemopreventive effects of tea have been conducted principally with green tea; limited studies have also assessed the usef ... | 1996 | 21544351 |
| search for antidiabetic constituents of medicinal food. | many foods are known to have not only nutritive and taste values but also medicinal effects. in chinese traditional medicine, the treatment using medicinal foods has been recommended highly. recently, we examined the effects of the extract and constituents of several medicinal foods on experimental models of diabetes. in this paper, we focus on the bioactive constituents of four medicinal foods, namely the antidiabetic constituents from 1) the roots, stems and leaves of salacia plants, 2) the ma ... | 2011 | 21628977 |
| coffee and tea consumption in relation to inflammation and basal glucose metabolism in a multi-ethnic asian population: a cross-sectional study. | abstract: background: higher coffee consumption has been associated with a lower risk of type 2 diabetes in cohort studies, but the physiological pathways through which coffee affects glucose metabolism are not fully understood. the aim of this study was to evaluate the associations between habitual coffee and tea consumption and glucose metabolism in a multi-ethnic asian population and possible mediation by inflammation. methods we cross-sectionally examined the association between coffee, gree ... | 2011 | 21631956 |
| (-)-epigallocatechin-3-gallate inhibits pancreatic lipase and reduces body weight gain in high fat-fed obese mice. | tea (camellia sinensis, theaceae) has been shown to have obesity preventive effects in laboratory studies. we hypothesized that dietary epigallocatechin-3-gallate (egcg) could reverse metabolic syndrome in high fat-fed obese c57bl/6j mice, and that these effects were related to inhibition of pancreatic lipase (pl). following treatment with 0.32% egcg for 6 weeks, a 44% decrease in body weight (bw) gain in high fat-fed, obese mice (p < 0.01) was observed compared to controls. egcg treatment incre ... | 2011 | 21633405 |
| changes of constituents and activity to apoptosis and cell cycle during fermentation of tea. | tea is believed to be beneficial for health, and the effects of the fermentation process on its contributions to apoptosis and cell cycle arrest of gastric cancer cells have not been completely investigated. in this study, the chemical components in green tea, black tea and pu-erh tea aqueous extracts were analyzed and compared. the polysaccharide and caffeine levels were substantially higher in the fermented black tea and pu-erh tea, while the polyphenol level was higher in the unfermented gree ... | 2011 | 21673927 |
| effects of the aqueous extract of white tea (camellia sinensis) in a streptozotocin-induced diabetes model of rats. | white tea (wt) is very similar to green tea (gt) but it is exceptionally prepared only from the buds and young tea leaves of camelia sinensis plant while gt is prepared from the matured tea leaves. the present study was investigated to examine the effects of a 0.5% aqueous extract of wt in a streptozotocin-induced diabetes model of rats. six-week-old male sprague-dawley rats were divided into 3 groups of 6 animals in each group namely: normal control (nc), diabetic control (dbc) and diabetic whi ... | 2011 | 21802923 |
| in vitro human skin permeation and cutaneous metabolism of catechins from green tea extract and green tea extract-loaded chitosan microparticles. | catechins are major antioxidants in green tea (camellia sinensis or camellia assamica), but because they do not permeate the skin well, the application of green tea in cosmetic products has so far been limited. this study aims to evaluate the cutaneous absorption of catechins from an extract of green tea and from a green tea extract-loaded chitosan microparticle. the catechin skin metabolism was also examined. the results suggest that chitosan microparticles significantly improve the ability of ... | 2011 | 21790662 |
| tea triterpenoidal saponins from the roots of camellia sinensis have inhibitory effects against alcohol dehydrogenase. | ten new polyhydroxyolean-12-ene pentacyclic triterpenoidal saponins, named rogchaponins 1- 10, were isolated from the methanolic extract of the roots of camellia sinensis by a series of chromatographic methods (silica gel flash column and c18 mplc followed by c18 hplc). their structures were established by 1d and 2d-nmr techniques along with ir and hr-tof-ms. rogchaponins r4 ( 4) and r5 ( 5) showed inhibitory activities against yeast alcohol dehydrogenase (adh) with ic (50) values of 16.1?±?3.2 ... | 2011 | 21786220 |
| synergistic anticancer activity of curcumin and catechin: an in vitro study using human cancer cell lines. | the most practical approach to reduce morbidity and mortality of cancer is to delay the process of carcinogenesis by usage of anticancer agents. this necessitates that safer compounds are to be critically examined for anticancer activity especially, those derived from natural sources. a spice commonly found in india and the surrounding regions, is turmeric, derived from the rhizome of curcuma longa and the major active component is a phytochemical termed curcumin. green tea is one of the most po ... | 2011 | 21780253 |
| tea polyphenols induce apoptosis through mitochondrial pathway and by inhibiting nuclear factor-kappab and akt activation in human cervical cancer cells. | phytochemicals present in tea, particularly polyphenols, have anticancer properties against several cancer types. however, studies elucidating the role and the mechanism(s) of action of tea polyphenols in cervical cancer are sparse. in this study, we investigated the mechanism of antiproliferative and apoptotic actions exerted by tea polyphenols on human papilloma virus-18-positive hela cervical cancer cells. treatment of green tea polyphenol (-)-epigallocatechin gallate (egcg) and black tea pol ... | 2011 | 21776820 |
| protective role of black tea extract against nonalcoholic steatohepatitis-induced skeletal dysfunction. | aim. this paper aimed to examine the chemoprotective actions of aqueous black tea extract (bte) against nonalcoholic steatohepatitis- (nash-) induced skeletal changes in rats. material. wistar rats (body wt. 155-175?g) of both sexes, aged 4-5 months, were randomly assigned to 3 groups; group a (control), group b (60% high-fat diet; hfd), and group c (hfd + 2.5% bte). methods. several urinary (calcium, phosphate, creatinine, and calcium-to-creatinine ratio) serum (alkaline phosphatase and serum t ... | 2011 | 21772972 |
| a subacute toxicity evaluation of green tea (camellia sinensis) extract in mice. | green tea is believed to be beneficial to health because it possesses antioxidant, antiviral and anticancer properties. the potential toxicity of green tea when administered at high doses via concentrated extracts, however, has not been completely investigated. the objective of the present study was to evaluate the safety of green tea extract in icr mice using a subacute exposure paradigm. in this study, mice were orally administered (gavage) green tea extract at doses of 0 (as normal group), 62 ... | 2011 | 21771628 |
| anti-uv activity of lentinus edodes mycelia extract (lem). | using our recently established simple method for evaluating protective activity from ultraviolet ray injury (referred to as 'anti-uv activity'), the effectiveness of various antioxidants and plant extracts was investigated. | 2011 | 21753126 |
| comparative healing property of kombucha tea and black tea against indomethacin-induced gastric ulceration in mice: possible mechanism of action. | the healing activity of black tea (bt) and bt fermented with candida parapsilosis and kombucha culture, designated as ct and kt respectively against the indomethacin-induced stomach ulceration has been studied in a mouse model. the kt sample (kt4) produced by fermenting bt for four days, showed the best dpph radical scavenging capacity and phenolics contents. hence the ulcer-healing activity of kt4 was compared with those of ct4 and bt. all the tea extracts (15 mg kg(-1)) could effectively heal ... | 2010 | 21776478 |
| modulation of hepatic cytochrome p450 activity and carcinogen bioactivation by black and decaffeinated black tea. | the principal objective of this study was to compare the ability of green, black and decaffeinated black tea to modulate hepatic expression of cytochromes p450 in the rat, and the consequences on the bioactivation of some food-borne carcinogens. furthermore, these studies allow inferences to be drawn as to the contribution of caffeine and flavanols in the tea-mediated changes in cytochrome p450 expression. black tea is prepared from fresh tea leaf following oxidation of flavanols by polyphenol o ... | 1999 | 21781908 |
| diversity analysis of diazotrophic bacteria associated with the roots of tea (camellia sinensis (l.) o. kuntze). | the diversity elucidation by amplified ribosomal dna restriction analysis and 16s rdna sequencing of 96 associative diazotrophs, isolated from the feeder roots of tea on enriched nitrogen-free semisolid media, revealed the predominance of gram-positive over gram-negative bacteria within the kangra valley in himachal pradesh, india. the gram-positive bacteria observed belong to two taxonomic groupings; firmicutes, including the genera bacillus and paenibacillus; and actinobacteria, represented by ... | 2011 | 21715960 |
| green tea polyphenols in drug discovery - a success or failure? | green tea is made from unfermented dried leaves from camellia sinensis and has been consumed by humans for thousands of years. for nearly as long, it has been used as a folk remedy for a wide array of diseases. more recently, a large number of in-vitro and in-vivo scientific studies have supported this ancient contention that the polyphenols from green tea can provide a number of health benefits. since these compounds are clearly safe for human consumption and ubiquitous in the food supply, they ... | 2011 | 21731575 |
| green tea catechin, epigallocatechin-3-gallate (egcg): mechanisms, perspectives and clinical applications. | an expanding body of preclinical evidence suggests egcg, the major catechin found in green tea (camellia sinensis), has the potential to impact a variety of human diseases. apparently, egcg functions as a powerful antioxidant, preventing oxidative damage in healthy cells, but also as an antiangiogenic and antitumor agent and as a modulator of tumor cell response to chemotherapy. much of the cancer chemopreventive properties of green tea are mediated by egcg that induces apoptosis and promotes ce ... | 2011 | 21827739 |
| plant polyphenols attenuate hepatic injury after hemorrhage/resuscitation by inhibition of apoptosis, oxidative stress, and inflammation via nf-kappab in rats. | purpose: oxidative stress and inflammation contribute to hepatic injury after hemorrhage/resuscitation (h/r). natural plant polyphenols, i.e., green tea extract (gte) possess high anti-oxidant and anti-inflammatory activities in various models of acute inflammation. however, possible protective effects and feasible mechanisms by which plant polyphenols modulate pro-inflammatory, apoptotic, and oxidant signaling after h/r in the liver remain unknown. therefore, we investigated the effects of gte ... | 2011 | 21698494 |
| genotoxic effects of green tea extract on human laryngeal carcinoma cells in vitro. | green tea (camellia sinensis) contains several bioactive compounds which protect the cell and prevent tumour development. phytochemicals in green tea extract (mostly flavonoids) scavenge free radicals, but also induce pro-oxidative reactions in the cell. in this study, we evaluated the potential cytotoxic and prooxidative effects of green tea extract and its two main flavonoid constituents epigallocatechin gallate (egcg) and epicatechin gallate (ecg) on human laryngeal carcinoma cell line (hep2) ... | 2011 | 21705301 |
| effect of milk and brewing method on black tea catechin bioaccessibility. | the aim of this study was to investigate whether milk reduces the bioaccessibility of tea catechins, which would compromise tea beneficial effects ascribed to polyphenols. adding milk to black tea has been shown to lead to polyphenol-protein complexes. so far, data on the intestinal stability of polyphenol-protein complexes are scarce. english black tea (0.93 -¦ 0.06 mol/l total catechins) and indian black tea (1.83 -¦ 0.08 mol/l catechins) were prepared with skimmed or full-fat milk and subject ... | 2011 | 21692489 |
| antimicrobial traits of tea- and cranberry-derived polyphenols against streptococcus mutans. | there are over 750 species of bacteria that inhabit the human oral cavity, but only a small fraction of those are attributed to causing plaque-related diseases such as caries. streptococcus mutans is accepted as the main cariogenic agent and there is substantial knowledge regarding the specific virulence factors that render the organism a pathogen. there has been rising interest in alternative, target-specific treatment options as opposed to nonspecific mechanical plaque removal or application o ... | 2011 | 21720161 |
| polyphenolics profile and antioxidant properties of raphanus sativus l. | raphanus sativus, a common cruciferous vegetable has been attributed to possess a number of pharmacological properties. antioxidant and radical scavenging activity of r. sativus root extracted with solvents of varying polarity were evaluated using different model systems. polyphenolic content was estimated to be in the range 13.18-63.54ôçëmgôçëg(-1) dry weight, with a considerable amount being obtained with polar solvents. high-performance liquid chromatography analysis indicated the presence of ... | 2011 | 21714734 |
| phylogenetic relationships of theaceae inferred from chloroplast dna sequence data. | tribal and generic relationships within theaceae were investigated using cladistic analyses of chloroplast-encoded rbcl and matk + flanking intergenic spacer region data. molecular data were employed because recent morphological and anatomical studies of tea (camellia sinensis) and related plant species provide conflicting support for tribal and generic relationships within the family. parsimony analyses of separate and combined data consistently identify three strongly supported lineages: theea ... | 2001 | 21669662 |
| rooibos (aspalathus linearis) offers cardiac protection against ischaemia/reperfusion in the isolated perfused rat heart. | rooibos, a unique south african herbal tea, is known to be an important source of unique polyphenolic compounds. in the present study we have quantified the main polyphenolic compounds in both fermented/traditional and unfermented/"green" rooibos (aspalathus linearis) and evaluated its cardioprotective effects against ischaemia/reperfusion injury. male wistar rats consumed aqueous rooibos and green tea (camellia sinensis) extracts (2%, w/v) for 7 weeks before their hearts were rapidly excised an ... | 2011 | 21982437 |
| effect of supplementation of soft drinks with green tea extract on their erosive potential against dentine. | matrix metalloproteinase (mmp) inhibitors reduce dentine erosion. this in vitro study evaluated the effect of the supplementation of soft drinks with green tea extract, a natural inhibitor of mmps, on their erosive potential against dentine. | 2011 | 21884149 |
| pu-erh black tea extract supplementation attenuates the oxidative dna damage and oxidative stress in sprague-dawley rats with renal dysfunction induced by subchronic 3-methyl-2-quinoxalin benzenevinylketo-1,4-dioxide exposure. | 3-methyl-2-quinoxalin benzenevinylketo-1,4-dioxide (quinocetone, qct), has been used to treat dysentery and promote growth in animal feeding. however, available data show that qct has potential nephrotoxicity. the present study was designed to investigate the protective effects of pu-erh black tea extract (pbte) which is a traditional remedy in china with antioxidant properties against oxidative dna damage and oxidative stress in a rat model of qct-induced renal dysfunction. increased serum crea ... | 2011 | 22079314 |
| Protective effect of black tea on integral membrane proteins in rat liver. | Ethanol intoxication is accompanied by oxidative stress formation. Consequently, it leads to disturbances in cellular metabolism that can alter the structure and function of cell membrane components. Black tea displays antioxidant properties, protects membrane phospholipids and may protect integral membrane proteins. In the present study, we examined whether black tea induces changes in the liver integral membrane proteins of 12-months old rats chronically intoxicated with ethanol. To estimate q ... | 2011 | 21920720 |
| Preparation, preliminary characterization, antioxidant, hepatoprotective and antitumor activities of polysaccharides from the flower of tea plant (Camellia sinensis). | In the present study, the crude polysaccharides from the flowers of tea plant (Camellia sinensis) (TFPS) were prepared with hot water and further fractionated on a DEAE-52 cellulose chromatography to afford three purified fractions of TFPS-1, TFPS-2 and TFPS-3. Then, their preliminary structures, antioxidant and antitumor activities in vitro and hepatoprotective activity in vivo were investigated. Compared with TFPS-2 and TFPS-3, TFPS-1 had relative higher content of sulfate and relative complic ... | 2011 | 22033094 |
| Dielectrophoresis enhances the whitening effect of carbamide peroxide on enamel. | To compare the enamel whitening effect of a 20-minute dielectrophoresis enhanced electrochemical delivery to a 20-minute diffusion treatment. | 2011 | 22165451 |
| A crude extract from immature green tea (Camellia sinensis) leaves promotes Toll-like receptor 7-mediated interferon-a production in human macrophage-like cells. | Toll-like receptor 7 (TLR7) senses viral single-stranded RNA (ssRNA), induces the production of type I interferons (IFNs), IFN-a and -ß, in macrophages such as dendritic cells (DCs), and its immune system protects the host from virus infection. Here, we found that a crude extract from immature green tea leaves (iTPS) containing a macromolecule with ssRNA fragments, induces IFN-a production in human macrophage-like cells. In addition IFN-a production was inhibited by treatment with TLR7 inhibitor ... | 2011 | 22124541 |
| Immunomodulatory effects of decaffeinated green tea (Camellia sinensis) on the immune system of rainbow trout (Oncorhynchus mykiss). | In order to study the immunomodulatory effects of decaffeinated green tea extract on rainbow trout, a study with a 30-day feeding trial was conducted. Commercial diets with graded levels of decaffeinated green tea extract, 20 mg (T1), 100 mg (T2), 500 mg (T3) per kg feed were prepared. 120 rainbow trout (35 ± 3 g) were randomly assigned to 4 groups in triplicates and fed one of the 3 experimental diets formulated or control diet. After feeding trial, 12 fish from each group were sampled for anal ... | 2011 | 21985858 |
| antibacterial effects of theaflavin and synergy with epicatechin against clinical isolates of acinetobacter baumannii and stenotrophomonas maltophilia. | stenotrophomonas maltophilia and acinetobacter baumannii are recognised as important nosocomial pathogens; however, due to their intrinsic resistance to multiple antibiotics, treatment options are limited. polyphenols from black tea have been shown to possess antibacterial action. in this study, the antibacterial effects of various concentrations of theaflavin as well as combinations of theaflavin and epicatechin were determined using the disk diffusion assay. the results showed strong antibacte ... | 2011 | 21885260 |
| Dietary agents in the prevention of alcohol-induced hepatotoxicty: preclinical observations. | Long term alcohol consumption is one of the important causes for liver failure and death. To complicate the existing problem there are no dependable hepatoprotective drugs and a large number of patients prefer using complementary and alternative medicines for treating and managing hepatic complications. Almost 25 centuries ago, Hippocrates, the father of medicine, proclaimed "Let food be thy medicine and medicine be thy food." Exploring the association between diet and health continues even toda ... | 2011 | 22119904 |
| black tea extract prevents lipopolysaccharide-induced nf-κb signaling and attenuates dextran sulfate sodium-induced experimental colitis. | black tea has been shown to elicit anti-oxidant, anti-carcinogenic, anti-inflammatory and anti-mutagenic properties. in this study, we investigated the impact of black tea extract (bte) on lipopolysaccharide (lps)-induced nf-κb signaling in bone marrow derived-macrophages (bmm) and determined the therapeutic efficacy of this extract on colon inflammation. | 2011 | 21989142 |
| a natural theaflavins preparation inhibits hiv-1 infection by targeting the entry step: potential applications for preventing hiv-1 infection. | theaflavins are the major components of tea polyphenols in brewed black tea. we previously reported that theaflavin derivatives, such as tf3, inhibited hiv-1 entry by targeting gp41. however, it is difficult to purify the individual theaflavins and the purified compounds are highly unstable. to develop theaflavins as affordable anti-hiv-1 microbide for preventing hiv sexual transmission, we intended to use an economic natural preparation containing 90% of theaflavins (tfmix). its antiviral activ ... | 2011 | 22155187 |
| a tea/vanadate decoction delivered orally over 14 months to diabetic rats induces long-term glycemic stability without organ toxicity. | vanadium can induce potent hypoglycemic effects in type 1 and type 2 diabetes mellitus animals, but toxic adverse effects have inhibited the translation of these findings. administration of vanadate in a black tea decoction has shown impressive hypoglycemic effects without evidence of toxicity in short-term studies. the purpose of this study was to investigate the hypoglycemic action and the toxic adverse effects of a tea/vanadate (t/v) decoction in diabetic rats over a 14-month treatment period ... | 2011 | 22146096 |
| fatty acid composition and antioxidant activity of tea (camellia sinensis l.) seed oil extracted by optimized supercritical carbon dioxide. | seeds are another product in addition to leaves (raw materials for teas) of tea (camellia sinensis l.) plant. the great increase of tea consumption in recent years raises the challenge of finding commercial applications for tea seeds. in the present study, supercritical carbon dioxide (sc-co(2)) extraction edible oil from tea seed was carried out, response surface methodology (rsm) was used to optimize processing parameters including time (20-90 min), temperature (35-45 °c) and pressure (50-90 m ... | 2011 | 22174626 |
| preventive effects of green tea (camellia sinensis var. assamica) on diabetic nephropathy. | purpose: this study aimed to evaluate the preventive effects of camellia sinensis var. assamica (csva) on diabetic nephropathy in in vitro and in vivo models. materials and methods: mdck cells were incubated with 1 mm of oxalate with or without different concentrations of csva, then mtt and malondialdehyde (mda) assays were performed to investigate the preventive effects of csva on oxalate-induced cytotoxicity and oxidative stress. thirty male db/db mice were divided into three groups. group 1 w ... | 2012 | 22187244 |