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contribution of adrenal medulla, spleen and lymph, to the plasma levels of dopamine beta-hydroxylase and catecholamines induced by hemorrhagic hypotension in dogs. 1979438992
the problem of interaction of shigella with epithelial cells.a review and analysis of data on the investigation of factors concerning the initial events of interaction of shigella with epithelial cells: attachment of penetration are presented. in the experiments with 3h-labeled bacteria it was shown that although common pili confer adhesive properties to bacteria but the penetration of shigella into the cell is not increased. it was stated that lps of shigella o antigen plays an important role not only in interaction with cellular and humoral factors of t ...1979442880
carcinogenic hydrocarbons increase the acceptance of transfer ribonucleic acid for methionine. 1979444273
thermodynamics and kinetics of the interaction of copper (ii) ions with native dna. 1979444636
dissociations between the effects of lsd on behavior and raphe unit activity in freely moving cats.the hypothesis that the action of hallucinogenic drugs is mediated by a depression of the activity of brain serotonergic (raphe) neurons was tested by examining the behavioral effects of d-lysergic acid diethylamide (lsd) while studying the activity of raphe neurons in freely moving cats. although the results provide general support for the hypothesis, there were several important dissociations. (i) low doses of lsd produced only small decreases in raphe unit activity but significant behavoiral ...1979451617
studies on conformational changes in f-actin of glycerinated muscle fibers during relaxation by means of polarized ultraviolet fluorescence microscopy.by means of polarized ultraviolet fluorescence microscopy the conformational changes of f-actin occuring in glycerinated muscle fibers of rabbit and barnacle (balanus rostratus hock.) under the influence of adenosine triphosphate in the presence of ethylene glycol bis(beta-amino-ethyl ether)-n,n'-tetraacetic acid were discovered. these changes seem to be located near the surface of the globules thus hampering the penetration of univalent iones and neutral molecules into the f-actin macromolecule ...1979470613
[biomass accumulation by polyploid forms of candida guilliermondii yeasts].under the action of a mitotic poison (acenaphthene), the haploid culture of candida guilliermondii assimilating n-alkanes yielded a polyploid form whose cells were four times larger, on the average, than in the haploid culture. when the pure culture was grown under stationary conditions in media with glucose, the economical coefficient, i. e. the ratio between the assimilated glucose and the accumulated biomass, was by 16, 47 and 157% higher in the polyploid culture than in the haploid one after ...1979470627
[exopolysaccharide and proteolytic enzyme synthesis by m-, s- and r-forms of mycobacterium lacticolum].the composition of exocellular polysaccharides was studied in the m, s and r variants of mycobacterium lacticolum 104. the exoglycans of the m and s variants were found to be rather similar but differ considerably from the exoglycan of the r form. the polysaccharides of the m and s cells contained glucose, mannose, galactose, and pyruvic acid; the exoglycan of the r cells contained also the fourth sugar arabinose, but lacked pyruvic acid. the specific rotation of the polysaccharides from the m, ...1979470628
an xyy man.this case report describes a young man with a 47, xyy karyotype who was convicted of arson. he suffered from a cardiac disorder which may well have been part of the xyy syndrome rather than a chance association. his abnormal karyotype was disclosed in court and used by the defence in a plea in mitigation.1979497632
cellular aspects of muscle growth: myogenic cell proliferation. 1979500507
purification and chemical characterization of antigens from sheep erythrocytes.a mixture of glycoproteins and glycolipids was solubilized from sheep erythrocytes membranes under the effect of high ionic strength (2 m nacl, 0.5 m tris). several antigenic fractions could be purified from the mixture using gel filtration on sephadex g-200 and block electrophoresis on pevikon c870; two fractions were found to raise antibodies in a primary reaction and these antibodies effectively sensitized erythrocytes to lysis by complement. the majority of other fractions elicited a weaker ...1979511033
the preoptic region of the merino sheep. 1979511043
[first results obtained in man with ethinyl estradiol sulfonate given for various indications (proceedings)]. 1979515140
[serum enzymatic activity in acute injury to the renal parenchyma].studied was the activity of the serum enzymes lap, ce, aph, sph, and guanase as well as the isoenzymes of the unspecific esterases and aph in guinea pigs treated with potassium bichromate. morphologically and histopathologically, an acute injury of the kidney parenchyma was found, being in close correlation with the size of lesions and these enzymes' activity. the activity of aph, sph, and ce rose, and that of lap and guanase did not change. these enzymes proved to form an appropriate constallat ...1979516440
[allergenic and anaphylactoid properties of carcinostatic compounds of platinum].different effects of platinum salts on the organism were studied comparatively. the toxic effect was estimated by ld50; the carcinogenic one--by the action on ehrlich ascites tumor; the anaphylactoid effect was evaluated by the degree of the arterial pressure fall, the development of bronchospasm and an increased blood histamine level in cats under intravenous injection of platinum salts. the sensitization action of platinum salts was assessed on guinea pigs. all these effects are found to be de ...1979516565
[assimilation of certain amino acids administered to animals of different ages].changes in the content of some amino acids (tryptophane, lysine, histidine and arginine) in blood plasma were studied in young and old rabbits administered lysine, arginine and urea into the stomach. a decrease in utilization rate of the test amino acids in old animals, their interdependence and the effect of urea administration on the lysine level in blood serum at a relatively stable content of tryptophane and histidine were established. a conclusion is drawn about the necessity of taking into ...1979516594
[dry adapting additive and its use in dairy products for approximating the composition of human milk].the paper concerns a procedure for a new product, dry adapting additive (daa), designed for manufacture of liquid substitutes of breast milk under industrial conditions. the chemical composition of adapted milk mixtures is compared to that of breast milk. procedures for adapted mixtures to be manufactured at city milk kitchens, food concentrate factories and under domestic conditions have been developed, with the mixtures being widely tried on clinical basis.1979516610
histologic diagnosis of diseases of malabsorption.the diagnoses which may be arrived at by examination of peroral small bowel mucosal biopsy specimens are presented. celiac sprue, unclassified sprue (refractory sprue), infectious gastroenterititis, stasis syndrome and kwashiorkor have a severe mucosal lesion. other clinical conditions are required to establish the diagnosis in these diseases. a number of diseases have specific diagnostic features. included are whipple's disease, abetalipoproteinemia, collagenous sprue, primary intestinal lympho ...1979517556
the kidney and ochratoxin a. 1979520974
competition among hexoses for hepatocellular uptake in the perfused liver of rat [proceedings]. 1979521922
[on the stiffness of human tibialis anterior muscle during voluntary contraction (author's transl)]. 1979522295
the mast cell: iii. distribution and maturation in various organs of the young rat.the changing population-density of mast cells in various organs was plotted for rats aged 1/2 to 90 days and correlated with histochemical studies on the stage of maturation of cells. mast cells are present at birth in liver and spleen and are particularly associated with foci of haemopoiesis. in bone marrow mast cells are absent at birth but become progressively more numerous with increasing age of the animal. the association of mast cells firstly with foci of extramedullary haemopoiesis and se ...1979523184
[receptors of human red blood cells for anti-tah and anti-ahp in the course of intravascular aging].human o-erythrocytes aged in situ do not expose free receptors for anti-t agglutinin of arachis hypogea. new receptors for concentrated anti-a agglutinin of helix pomatia are manifested but are lost again in the course of further ageing of the cells in situ. a remasking of exposed receptors for anti-tah and anti-ahp byautologous, strongly binding globulins is supposed. these globulins could constitute the decisive signal for the autologous phagocytosis of senescent red blood cells.1979525143
reticulo-rumen motility in the chronically vagotomized sheep [proceedings]. 1979529098
adrenergic responses to transmural electrical stimulation of the guinea-pig gall-bladder [proceedings]. 1979529152
lipid metabolism in rats fed a diet with high citrus pectin content. 1979532387
[lodgement of the intraventricular catheter into cerebral parenchima in infantile hydrocephalus (author's transl)].ten cases of hydrocephalus of diverse ethiology, treated with ventriculo-peritoneal shunt are presented. in following controls it was observed that extreme of the catheter was located in cerebral parenchima. these features were followed of minimal clinics alterations and electroencephalographic focal manifestations. the pathogenesis of the complication due to the findings in the computerized axial tomography (cat) and the real value in the diagnosis of this complication are analized.1979533055
identification of a new allele of es-i segregating in an inbred strain of mice.a new allele of es-1, designated es-1e, has been identified in the mouse. this allele was discovered segregating among the progeny of a strain dba/2j male and is apparently the result of a spontaneous mutation within this strain. genetic analyses have shown that this mutation is heritable and, further, that both heterozygous and homozygous progeny are viable and fertile. to date, no discernible deleterious effects have been identified as associated with this mutation.1979540008
effect of sodium hydroxide upon protein binding to filter paper disks and its significance in the determination of protein in colorimetric and radioisotopic assays. 1979543545
restoration of metabolic cooperation in heterokaryons between hgprt-deficient mouse a9 fibroblasts and chick embryo erythrocytes.genetic determinants of metabolic cooperation were studied by fusing chick erythrocytes to hgprt- mammalian cells. heterokaryons were then tested for their ability to incorporate [3h]hypoxanthine and to transfer radioactive material to hgprt- recipient cells. chick erythrocytes (ce) have nuclei which are inactive but contain the hgprt gene and some cytoplasmic hgprt enzyme activity. they are unable, however, to cooperate with hgprt- cells. of the two mammalian cell lines used, the human gm29 lin ...1979545717
convergence of human age-sex distributions to an equilibrium-state age-sex distribution. 1979545730
beta-[1-phenyl-5-bis(beta-chloroethyl)-amino-benzimidazolyl-(2)]-dl-alanine (zimet 3164): an immunosuppressant without marked anti-cancer effect.zimet 3164 inhibited the growth of sarcoma 180 p, sarcoma 180 g, and walker 256 carcinosarcoma, but was unable to prolong the survival time of mice bearing ehrlich ascites carcinoma or the leukaemias l 1210 and laj i to a worthwhile extent. the primary and secondarantly suppressed in mice. the drug exerted maximum effect when given on days--2 to +2 relative to antigenic stimulus. administration exclusively prior to immunization induced only moderate immunosuppression while injection afterwards f ...1979546175
some chemical and nutritional properties of acylated fish protein. 1979546957
correlation between gross observations of tumors and neoplasms diagnosed microscopically in carcinogenesis bioassays in rats.microscopic diagnoses of spontaneous and induced neoplasms in f344 rats in two carcinogenesis bioassays were correlated with the gross observations made at the time of necropsy. the results for a negative and a positive compound with reference to carcinogenicity, indicate that of the gross descriptions indicative of tumors, 37 percent and 24 percent respectively, were not diagnosed as neoplasms microscopically. however, some of the gross lesions were diagnosed histologically as nonneoplastic les ...1979547015
[lectins as reagents for the differentiation of serum enzymes. lectins as reagents, i. (author's transl)].lectins from canavalia ensiformis, phaseolus vulgaris, and triticum vulgare react with arylamidase, alkaline phosphatase, gamma-glutamyltransferase, and cholinesterase of human sera by formation of enzymatically active, mostly insoluble complexes. arylamidase, alkaline phosphatase, and cholinesterase react more intensely in sera of healthy people than in sera of patients with liver and neoplastic diseases. arylesterase is bound to a distinct degree only by concanavalin a. the enzymes mentioned a ...1979547035
[electron microscopical evidence of spiroplasma citri in nucleus of infected testplants (author's transl)].this is the first report for the evidence of mycoplasmas in an organelle of a plant cell. spiroplasma citri was detected by electron microscopy in the nucleus of a phloem parenchyma cell of chrysanthemum carinatum schousboe plants, inoculated experimentally by euscelis plebejus fall.1979549392
construction of haloaromatics utilising bacteria. 1979551259
aspartame: assessment of developmental psychotoxicity of a new artificial sweetener. 1979551307
postnatal behavioral changes in prenatally irradiated rats.rats were exposed on gestational day 15 to 125 r x-irradiation, a treatment known to severely alter brain morphology. at 4-6 weeks of age the behavior of these animals was studied using two methods: (1) measurement of circadian locomotor activity, (2) photographic analysis of behavioral acts. the circadian locomotor activity of irradiated rats was similar to that of controls tested individually or as groups in a residential unit. after morphine sulfate, 2 mg/kg, the increase in locomotor activit ...1979551312
studies on the inhibitory effects of zinc heptanoate on microorganisms.inhibitory effect of zinc heptanoate was observed on different cultures of bacteria and fungi. growth of all the bacteria was inhibited by the compound. greatest inhibition was seen in the case of staphylococcus albus, streptococcus pyogenes, shigella dysenteriae, shigella sonnei, shigella flexneri, salmonella typhi, s. paratyphi a, s. paratyphi b, vibrio cholerae, corynebacterium diphtheriae, and e. coli whereas least inhibition was found in the case of staphylococcus aureus. in triethanolamine ...1979553835
dog bites.dog bites can be prevented by proper education of children, appropriate selection of family pets and the restraint of guard dogs in the community. an unusually high incidence of bites by german shepherds was observed in this study. treatment of injuries inflicted by dogs should include: careful wound toilet, appropriate excision of damaged tissues, careful wound repair with adequate drainage and systematic therapy with selected antibiotics.1977556659
oxolinic acid for the treatment of chronic gastrointestinal shigella carriers.two patients were long-term gastrointestinal carriers of shigella flexneri for 23 mo and 6 mo, respectively. neither patient responded to oral antibiotics, despite in vitro sensitivity of the bacteria to the antibiotics administered. oral oxolinic acid produced immediate cessation of the carrier state in both patients, with resolution of minor but persistent physical complaints.1978686252
trimethoprim-sulfamethoxazole therapy for shigellosis.twenty-eight infants and children hospitalized for severe shigellosis were treated orally either with ampicillin trihydrate (100 mg/kg/day administered in divided doses every six hours) or with trimethoprim-sulfamethoxazole (trimethoprim, 10 mg; sulfamethoxazole, 50 mg/kg/day in divided doses every 12 hours) for five days. four patients with ampicillin-resistant shigellae continued to have diarrhea and positive stool cultures during therapy. patients with susceptible shigellae treated with ampic ...1976765518
[cellular infiltration of shigella]. 1975765541
[phagocytosis of shigellas with hela cells]. 1975765698
[rectoromanoscopic pictures in dysentery associated with helminthic diseases]. 1975765713
[construction of new types of chemical vaccines for the prevention of intestinal infections, and their qualitative assessment. iv. physical properties and immunological characteristics of the experimental series of chemical vaccines presented for comparative study].the authors present the results of study of physico-chemical properties of the chemical sorbed monovaccines from the antigens of the causative agents of typhoid fever, paratyphoid a and b and sonne and flexner dysentery obtained by various methods; the results of investigation of their reactogenic properties and immunological activity of limited groups of volunteers also given. the vaccines from the antigens obtained by sparing methods were less reactogenic than the rest experimental and control ...1975766526
[characteristics of bacteriophages used in the detection of disturbances in the synthesis of the o-antigen polysaccharide of shigella flexneri].a study was made of the sensitivity spectra of various strains of sh. flexneri and r-mutants of various chemotypes to bacteriophages used for lysotyping of shigellae and to some bacteriophages specific of the r-mutants of salmonellae and e. coli. as a result of study there was selected and characterized a collection of bacteriophages specific of the s-strains and r-mutants of shigellae of different chemotypes, which could be used in genetic and immunochemical investigations.1975766530
immunochemical studies on the serotype of shigella flexneri and its recombinant.chemical and serologic analysis of polysaccharides of shigella flexneri 2b and its recombinant revealed complete defect of the gene responsible for type ii specificity as a result of recombination. at the same time, function of the gene in the same locus responsible for 7,8 group specificity was partially inhibited. attenuation of group antigen 7,8, associated with partial uncovering of the structure of the basic chain, causes appearance of a distinct 3,4 group antigen. changes of this type in s ...1975766721
comparative serologic analysis of lac+ recombinants of serotypes 2a, 2b, 5a and variant y of shigella flexneri.the serologic structure of lac+ recombinants of 2a, 2b, 5a and var. y serotypes of sh. flexneri was compared. rec. 2a lac+, rec. 2b lac+ and rec. y lac+ were shown to be identified, and rec. 5a lac+ was found to differ from those mentioned in that it was deficient in determinants for 3,4 group antigen complex. furthermore, the paper discusses the presumable genetic mechanisms of the described variability.1975766722
diagnostic value of indirect hemagglutination in the seroepidemiology of shigella infections.to evaluate the usefulness of the indirect hemagglutination (iha) test in the epidemiological investigation of shigellosis, single serum specimens were tested from 50 patients with shigella dysenteriae 1 (shiga bacillus) infections, 103 asymptomatic contacts of these cases, 267 adult and 100 student control, and serum specimens collected during two outbreaks caused by s. sonnei and one outbreak due to s. flexneri 6. in patients with s. dysenteriae 1, 74% demonstrated titers of greater than or eq ...1976767361
[intestinal localization of shigellae in dysentery and experimental shigellosis].the investigation of 53 section cases of dysentery and 18 biopsy specimens of the large intestine in acute dysentery in children showed that intrapithelial distribution of shigella was not always regular. in studies of experimental shigellosis on isolated loops of the intestine 459 segments of the intestine of 51 rabbits were investigated. the results obtained showed that shigella multiplied mainly in the lumen of the intestine. the increase in number of shigella in enterocytes was by 8-9 orders ...1976769758
[bacteriological and epidemiological considerations on shigelloses in south vietnam (1969-1973)].during the period from 1969 to 1973, a rectal swabs from 13.943 diarrhea patients of all ages were examined by bacteriological surveys. from these specimens, 981 strains of shigella were isolated. the most commonly encounted were shigella flexneri 2. all of strains of shigella isolated were highly resistant to aureomycin, tetracyclin, terramycin, novobiocin and chloramphenicol. there has been an increase in the development of multiresistance of shigella. colimycin and streptomycin were the most ...1975770024
isolation and analysis of the lipid a backbone. lipid a structure of lipopolysaccharides from various bacterial groups.a degradation procedure of lipopolysaccharides was worked out which allows the isolation of the reduced backbone of lipid a in a total yield of between 20 and 30%. this procedure was applied to lipopolysaccharides of s forms (salmonella minnesota, shigella flexneri 5b, escherichia coli 086, e. coli 0111, xanthomonas sinensis, rhodopseudomonas gelatinosa) and r mutants (salmonella minnesota, shigella flexneri, 5b, e. coli bb9 and e. coli eh 100). chemical analysis, reaction with beta-n-acetyl-glu ...1976770165
[observations on the sensitivity to antibiotics of the shigella isolated from patients in 1966-1973].sensitivity to levomycetin, streptomycin, chlortetracycline, oxytetracycline, monomycin, neomycin and erythromycin of 3766 strains of shigella isolated from dysentery patients within 1966-1973 was determined with the method of standard discs. the strains proved to be resistant to tetracycline (94.3-99.4 per cent), streptomycin (85.1-94.9 per cent) and levomycetin (69-93.1 percent). by present the dysentery bacilli have preserved their sensitivity to monomycin (88.2 per cent) and neomycin (98.2 p ...1975773290
[the influence of several prophages on the genetic behavior of flexner dysentery bacteria].in conjugation experiments of escherichia coli k-12 hfr strains and converted clones of shigella flexneri var. y(-:3,4) that had acquired the capacity to synthesize type of antigens iv or v it is confirmed that the locus linked to lac-pro region in sh. flexneri chromosome called tp locus is a site of an attachment of prophages responsible for certain type specific antigens. lac+ hybrids of the clone converted by phage iv lost the type specific antigen iv with the frequency comparable with the lo ...1975773758
shigella hepatitis. 1976775138
[correlation between biochemical features and pathogenicity of shigella. iv. threonine deaminase of shigella strains producing and not producing keratoconjunctivitis in guinea pigs]. 1976775224
[characteristics of the salmonella and shigella strains isolated from diarrhea patients during antibiotic therapy].drug resistant strains of salmonella and shigella were isolated from diarrhoeic children during antibiotic treatment. two strains of sh. flexneri serotype 2a, resistant to sulfonamides, streptomycin,chloramphenicol, and tetracyclines, were able to transfer "en bloc" their resistances to e. coli k12.1975776095
studies on the survival of shigella flexneri in river and tap water. 1975776123
shigella flexneri 6 biotypes: a review.except in gas production, s. flexneri 6 is generally similar to other s. flexneri. s. flexneri 6 contains both aerogenic and anaerogenic strains which are identical serologically. it is not surprising that s. flexneri 6 is not separable from other s. flexneri types on the basis of dna relatedness (overall genetic makeup) (4). the manchester biotype is seen in the united states, and is easily separable from other enterobacteriaceae by biochemical tests. one can no longer assume à priori that any ...1976776900
proceedings: on new biological responses of conventional adult mice administrated with bacterial endotoxin. 1975778449
[importation of shigelloses into the german democratic republic]. 1975779290
shigellosis in custodial institutions. v. effect of intervention with streptomycin-dependent shigella sonnei vaccine in an institution with endemic disease.a double-blind controlled field trial of live, oral, streptomycin-dependent shigella sonnei vaccine was begun in an institution with endemic s. sonnei disease. considerable unexpected child-to-child transmission of the vaccine strains inadvertantly caused the field trial to resemble a mass vaccination campaign. although s. sonnei accounted for 90% of shigella infections from 1968 to 1971 and three-fourths of the cases occurred in the seven study cottages, s. sonnei disease disappeared following ...1976779465
proceedings: inactivation and mutation of cultured mammalian cells by radiations of different let. 1976779917
serum amylase in rats following the administration of endotoxin. 1976781914
[an electron microscopic study of the interaction between shigellae and cell cultures. ii. structuro-functional response of the chief cytoplasmic organoids of infected cells].the initial mobilization of the protective power of amniotic cells under the influence of the intracellular parasite shigellae flexner was shown using qualitative and quantitative methods of electron microscopy. this mobilization is seen in the appearance and then concentration of membrane elements of the endoplasmic reticulum around the bacteria. the character of some degenerating changes confirms the opinion about the presence of an excreting endotoxin fraction in shigellae flexner.1975781958
[the role of the water factor in the spread of dysentery on river vessels].results of epidemiological and statistical analysis of the indices of dysentery morbidity and bacteriological examination of drinking water pointed to the significant role of the water factor in the spread of dysentery on the river vessels.1976782097
[increasing the frequency of the transmission of antibiotic resistance in bacteria through their centrifugal sedimentation]. 1976782110
[use of the vshs elective-differential medium in the diagnosis of dysentery and other acute intestinal infections].results of trial of the vshs medium under conditions of direct seeding feces of patients suffering from dysentery and other acute intestinal disturbances demonstrated that by the efficacy of sh. sonnei isolation it failed to differ from ploskirev's bactoagar, was less effective in comparison with levin's medium with levomycetin (the incidence of shigella isolation was 49.7, 52.6 and 60.3%, respectively) and was the most effective in sh. newcastle isolation. in seeding feces after their enrichmen ...1976782114
antigenicity testing of inactivated oral enteric bacterial vaccines for human use.this study deals with the laboratory testing of the antigenicity of inactivated oral enteric bacterial vaccines for human use, viz. typhoid, dysentery, escherichia coli and cholera vaccines. for the assays the following methods are applied : 1) various types of active mouse protection tests 2) serum and coproantibody determinations in immunized persons and experimental animals, 3) protective ability of the immune sera in mice and embryonated eggs, 4) hemolytic and bacteriolytic plaque assays. it ...1976782974
[epidemiology of bacterial dysentery in the usa]. 1976785885
[antibody-containing cells in the mucosa of the large intestine of patients with acute bacterial dysentery].the authors traced the dynamics of appearance, increase and disappearance of o-antibody-containing cells in the mucosa of the distal portion of the large intestine in patients suffering from acute sonne and flexner dysentery (aspiration biopsy of the mucosa). the antibodies were revealed by the indirect coons method. the total number of cells per 1 mm2 of 4 mum of the mucosal section the number of lymphoid cells and the content of the antibody-containing cells in % per total cell count of the ly ...1976785886
fecal steroids in diarrhea. i. acute shigellosis.fecal bile acid and neutral sterol patterns of five healthy adult male volunteers, who were challenged by a virulent shigella flexneri 2a (m42-43) strain and developed dysentery were studied. it was observed that cholic acid was increased from 1.9 +/- 0.4% of total bile acid in the feces before infection to 14.5 +/- 2.1% during diarrhea (p less than 0.001). chenodeoxycholic acid also was increased from 3.2 +/- 0.7 to 8.7 +/- 3.2% in diarrhea but the difference was not significant statistically. ...1976786002
[ 771 shigella strains isolated in a 15-year period from americans living in ankara. comparisons with shigella strains isolated from turkish natives].the author had worked as a bacteriologist in ankara american air force hospital from 1958 to 1972. during this period of time he was able to isolate 771 shigella strains from the american patients of the hospital. the amounts and the percentages of the subgroups are listed below together with the two other ankara city pediatric hospital results (see article). american community lived in ankara for 15 years and shared many aspects which were important in shigella epidemiology like using city's ta ...1976790107
[shigellosis in tucumán].in 731 diarrhea cases studied from january 1971 to june 1973 in tucumán a significant increase of shigellosis in eutrophic children was observed. the frequency of shigella isolations, considering all the enteropathogens found, were: 15,5 %; 13 % and 21,3 % in 1971, 1972 and 1973, respectively (table 1). all the strains of shigella isolated belonged to the shigella flexneri b or shigella sonnei d groups, being the percentage for the former 78 % in 1971; 93 % in 1972 and 77 % in 1973 (table 2). th ...1975790480
shigellosis transmitted by nurses.twelve cases of shigella sonnei infection, with two deaths, occurred at a custodial institution in donelson, tennessee, in april and may 1973. nine of the cases and both deaths were in patients hospitalized at the institution's infirmary. the patients with nosocomial shigellosis were significantly younger and had been hospitalized significantly longer than controls. epidemiologic investigation implicated staff members in the transmission of illness from one patient to another and identified the ...1976790590
[cytotoxic factor of flexner shigella, its biologic function and genetic control]. 1976790817
[role of the cytotoxicity of shigellae in the infectious process]. 1976790818
[realization of the cytotoxic properties of flexner shigellae in a macrophage culture at the cellular and subcellular level]. 1976790819
[change in the virulence of flexner shigellae following transmission of several parts of chromosomes related to the synthesis of o-antigen lipopolysaccharide from e coli k-12 and r-mutants of shigellae]. 1976790821
[comparative study of the virulence of an antibiotic-sensitive strain of flexner dysentery and its exconjugants with different r-factors acquired in the experiment]. 1976790825
[transmissive plasmid determining hemolysin production and synthesis of thermolabile k-antigen]. 1976790826
on the metabolic characteristic of hybrids shigella flexneri x escherichia coli devoid of their ability for intracellular multiplication in the epithelial cells. i. glycolysis.the glycolysis (aerobic and in the presence of kcn) of avirulent xyl+ and xyl-str hybrids sh. flexneri x e. coli, devoid of their ability to multiply intracellularly in the epithelial cells, is studied. it is established that their glycolytic activity is considerably higher than the activity of the donor strain e. coli, and deviate significantly compared with shown activity of the virulent recipient strains sh. flexneri. xyl-str hybrids are showing high values of glycolysis in aerobic conditions ...1976790853
on the metabolic characteristic of hybrids shigella flexneri x escherichia coli devoid of their ability for intracellular multiplication in the epithelial cells. ii. catalase and phosphatase activity.the catalase and phosphatase activity of avirulent by keratoconjunctival test of guinea pigs xyl+ and xyl-str (kcp-) hybrids that have lost their ability for intracellular multiplication, received from virulent strains. sh. flexneri (sh. flexneri 222 5 a and sh. flexneri m42-43) and donor strain e. coli ab 313 was investigated. it is established that there is a definite dependence between the changes in the catalase and the phosphatase activities of the hybrid strains and the newly received by t ...1976790854
shigellosis in the united states: ten-year review of nationwide surveillance, 1964-1973.in the 10 years 1964-1973, 105,832 isolations of shigellae were reported to the center for disease control through a nationwide surveillance system. the number reported increased by approximately 13% annually, from 5852 in 1964, when only 17 centers reported all 4 quarters; to 16,797 in 1973, when 52 centers reported each quarter. the rate of reported isolations varied from 4.6 per 100,000 persons in 1965 to 9.1 per 100,000 in 1973. shigella sonnei accounted for 64% of all these isolates and for ...1976790947
[effect of specific sensitization of the body on the clinical symptoms of dysentery]. 1976793040
studies on the energetic metabolism of shigella flexneri x escherichia coli hybrids devoid of penetration ability. iv. growth characteristics in the presence of some tricarboxylic acid cycle intermediates.the dynamics of avirulant lac+kcp- hybrids sh. flexneri multiplication was investigated in minimal medium in the presence of some tricarboxylic acid cycle intermediates (fumarate, succinate, malate) and pyruvate. it was established that in spite of the loss of virulence in the rate of the multiplication of the hybrid strains, in comparison with that of the virulent recipient strains of sh. flexneri, considerable differences were not observed.1976793258
[free amino acid content in the blood and urine from the use of monomycin on children with dysentery].the progress of acute dysentery in 73 children at the age of 1 to 14 years treated with monomycin and the levels of free amino acids in the blood and urine in dynamics were studied. it was found that the blood levels of 6 amino acids in the children treated with the antibiotics significantly decreased, while those of 3 amino acids increased as compared to the levels of the same amino acids in the children treated without the antibiotics. it was concluded that the diet of dysentery children treat ...1976793513
[change in the sensitivity of dysentery bacteria to certain antibiotics, furazolidone and antifungal preparations when cultured together with candida albicans].the effect of candida albicans (2 collection cultures and 1 freshly isolated culture) on sensitivity of dysentery bacteria (5 zonne strains, 4 flexner strains and 2 newcastle strains) to antibiotics, furazolidone and their combinations with nystatin or decamine was studied by the method of serial dilutions. a total of 937 tests were performed with the use of 10 concentrations in each test. it was found that sensitivity of the shigella to levomycetin succinate, monomycin and furazolidone decrease ...1976793515
studies on the relationships between the immunogenicity and catabolism of antigens and their binding to the surface of macrophages.the relationship between immunogenicity of shigella paradysenteriae, the branched synthetic polypeptide poly-l (tyr, glu)-polylpro-polyllys [(t, g)-pro--l] and human albumin (hsa) interacting with macrophages and kinetics of antigen degradation and degree of binding to the cell surface was studied. following thioglycollate inoculation into c57bl/6 mice, the peritoneal-stimllated macrophages had higher levels of hydrolases as compared to unstimulated cells. the lysates of the stimulated macrophag ...1976793850
[formation of f'-episomes in flexner shigellae].genetic characteristics of shigella flexneri virulent donor strain 3s, isolated in the laboratory, are studied. the data obtained showed that sh. flexneri 3s 6832 is of f'protype it did not transmit even closely located chromosome markers, except pro+. the transition of pro+ marker was reproduced in reca- strain. f'pro plasmid was eliminated with a frequency similar to that of f'lac factor in the control strain of escherichia coli. the study of virulence by means of keratoconjunktival test revea ...1976793929
phage-dependent changes in shigella flexneri type antigen synthesis.lysogenic conversion of shigella flexneri type antigens was studied with the aid of wild-type and thermosensitive mutant phages. with all wild-type phages, the appearance of glycosylated antigen was accompanied by the appearance of polyprenyl phosphate glucose synthetase activity. with some of the mutant phages, the appearance of glycosylated antigen was not followed by the formation of lipid-linked glucose in the enzyme assay. the reverse has also been observed, i.e., the high rate of formation ...1976793990
[comparative susceptibility of animals to sonne and flexner dysentery]. 1976794642
[importance of cellular and humoral immunity factors in dysentery in children]. 1976795153
[interaction with the hep-2 epithelial cells of sh. flexneri r mutants and hybrids differing in o antigen structure].the results of a study of the interaction of the r-mutants of sh. flexneri of various chemotypes and shigellae hybrids with a definite genetic characteristics differing by structure of the o-antigen labeled with 3h-glucose, with the cells of the hep-2 line demonstrated that the presence of the full value lipopolysaccharide structure apparently promoted the fixation of shigellae to the epithelial cells. the rough shigellae strains could retain the capacity to penetrate into the cells and to multi ...1976795229
[changes of various factors of nonspecific humoral immunity in acute dysentery].the level of total enterobacterial enterotoxins of the blood serum, of beta-lysins, lysozyme activity, complement and normal antibodies were studied in 191 patients with acute flexner dysentery and in 285 patients with acute sonne dysentery, depending on the period of the disease, its severity, the treatment applied, and the species of the causative agent. the level of the nonspecific humoral immunity factors increased before the treatment and its normalization depended on the treatment applied.1976795232
[a study of pancrealysates of sh. flexneri 2a and sh. sonnei fractionated by filtration through sephadex g-200 and ultracentrifugation].a high-molecular fraction of the o-antigen of sh. flexneri and sh. sonnei was isolated from the antigen complex by gel-filtration through sephadex g-200 and ultracentrifugation. the high-molecular fraction obtained by ultracentrifugation at 105000 g contained no low-molecular components.1976795248
[ultrastructural features of the interaction of salmonellae and shigellae with the cell]. 1976796637
[dysentery in the city of biaƂystok in the years 1961-1974]. 1976796895
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