Publications

TitleAbstractYear
Filter
PMID
Filter
development of a simple method for concentrating enteroviruses from oysters.the development of a simple method for concentrating enteroviruses from oysters is described. in this method viruses in homogenized oyster tissues are efficiently absorbed to oyster solids at ph 5.5 and low salt concentration. after low-speed centrifugation, the supernatant is discarded and viruses are eluted from the sedimented oyster solids by resuspending them in ph 3.5 glycine-buffered saline. the solids are then removed by low-speed centrifugation, and the virus-containing supernatant is fi ...1975234154
amino acid composition of cerebrospinal fluid in actue neuroinfections in children.a survey of the cerebrospinal fluid (csf) amino acids, glutamine, and glutamic and gamma-aminobutyric (gaba) acids was made in 168 children, aged 1 to 14 years, with various neurological infections. the glutamic acid and glutamine concentrations in the csf of children with severe forms of acute serous and bacterial meningitis were about three to four times as great as in controls. the indices returned almost to normal during recovery. gaba is absent in normal csf, but appeared in the csf of pati ...1975234733
microbiology of diseases of tonsils and adenoids. 1975236724
inactivation of enterovirus by glutaraldehyde.a study on the rate of inactivation by glutaraldehyde of coxsackievirus was conducted using different concentrations, temperatures, and ph values. it was found, that 2 percent glutaraldehyde at ph 7.4 and 25 c, as recommended for a sporicide, reduced the titer of infectious virus by 2 log10u in 1 min or less. the reduction was not negatively affected by high concentrations of organic matter (serum and animal spillings) in the reaction mixtures.1975238467
an outbreak of acute hemorrhagic conjunctivitis in yugoslavia in 1973.an outbreak of approximately 200 cases of acute hemorrhagic conjunctivitis is described in prekmurje, a northern province in yugoslavia. the epidemic was caused by enterovirus type 70, serologically identical with the causative agents of similar outbreaks in london and japan. the origin of the outbreak could not be elucidated but a link was seen between this case and a small outbreak in veenendaal in the netherlands.1975239379
association of enteroviruses with natural and artificially introduced colloidal solids in water and infectivity of solids-associated virions.encephalomyocarditis viruses adsorb to introducted organic and inorganic solids in water over a wide range of ph and with various concentrations and species of metal cations. visible flocculation of solids was not a prerequisite for significant virus association. virus adsorption to natural solids in various types of natural waters was significant but variable. clay-adsorbed virus retained its infectivity in tissue culture monolayers. these solids-associated viruses also retained infectivity in ...1975240308
diagnosis of rhinovirus-infections by virological and immunofluorescent methods.in january--may, 1971, detection of rhinoviurs infections among ambulatory patients with respiratory diseases in moscow was carried out in parallel by virological and immunofluorescent methods. rhinovirus infections were virologically confirmed in 13% out of 238 patients. by the indirect immunofluorescence technique, rhinovirus antigens of serotype 17 were detected in 2.2% out of 220 patients, of type 1b in 4.3% out of 183 patients, of type 48 in 5.6% out of 123 patients and of type 7 in 4.6% ou ...1975241246
lack of relationship between viruses and human diabetes mellitus.antibodies titres against coxsackie-b (cb) and mumps virus (mv) were determined in 180 normal subjects and two groups of diabetics, 236 with diabetes of recent onset (dro) and 108 with diabetes of long duration (dld). positive antibody titres to these viruses were found more frequently in controls than in diabetics. in fact, the percentage of positive titres was significantly less than in controls in several instances particularly in juvenile onset diabetes of long duration. these data suggest t ...1977268169
the investigation of a recurrence of an ahc virus epidemic at lucknow: a serosurvey for ahc virus antibodies before and after the epidemic.an epidemic of acute haemorrhagic conjunctivitis (ahc) recurred at lucknow during july to september 1975, after a gap of 4 years. out of the 35 cases investigated thoroughly, 20 entero-70-like cytopathogenic agents were isolated from the conjunctiva which were neutralized by antisera against ahc virus j670/71 of japan. seroconversion was seen in 7 out of 11 paired sera from patients. serological study was also done on 100 sera collected before the ahc epidemic of 1971, 100 sera after 1971 and 10 ...1977269197
generation of cytotoxic t lymphocytes during coxsackievirus b-3 infection. i. model and viral specificity1.the production of cytotoxic cells in the spleen of adult male balb/c mice infected with coxsackievirus b-3 has been examined. an in vitro 51cr release assay was used to measure cytotoxic activity against virus-infected and uninfected neonatal sygeneic fibroblasts. cytotoxicity of immune spleen cells against virus-infected targets was detected on the 3rd day after infection, reached a peak on day 7, and then declined to low levels by days 12 and 14. spleen cells obtained 3 and 5 days after infect ...1977300399
generation of cytotoxic t lymphocytes during coxsackievirus tb-3 infection. ii. characterization of effector cells and demonstration cytotoxicity against viral-infected myofibers1.this report describes studies characterizing the virus-specific cytotoxic effector cells which are present in the spleens of mice 7 days after infection with coxsackievirus b-3. an in vitro 51cr assay employing eyngeneic virus-infected neonatal fibroblasts was used to measure cytotoxic activity. treatment of immune cells with (anti-thy-1.2) and complement abolished dtheir cytotoxic activity, but no reduction occurred when b cells were removed by incubation with anti-ig and complement or macropha ...1977300400
persistent and fatal central-nervous-system echovirus infections in patients with agammaglobulinemia.we observed persistent echovirus infection of the central nervous system, as defined by continued presence of isolatable virus in cerebrospinal fluid, in five patients with agammaglobulinemia. the immunologic deficit in each was characterized by absence of surface-immunoglobulin-bearing b lymphocytes and of lymph-node cortical follicles, but normal t-cell function. echoviruses 30, 19, 9 and 33 were recovered from cerebrospinal fluid for periods varying from two months to three years. the patient ...1977301244
generation of cytotoxic t lymphocytes during coxsackievirus b-3 infection. iii. role of sex. 1977301899
[t-lymphocytes and b-lymphocytes in meningitis caused by echo-9 enteroviruses]. 1977302939
nine-year study of who virus reports on fatal viral infections.in 1963, the world health organization established a system for the collection and distribution of information on viruses. the present study is based on 2737 reports of fatal viral infections received from laboratories in 39 out of a total of 47 countries participating in the scheme. in the industrially developed countries, from which most of the reports came, more than one-third of the total number of deaths were associated with influenza a virus, while in the developing countries, the enterovi ...1977304388
effect of viral infection on drug metabolism and pesticide disposition in ducks. 1978310588
recovery of viruses from field samples of raw, digested, and lagoon-dried sludges.in a 22-month study, viruses were detected in 84% (62/74) of raw, 53% (19/36) of anaerobically digested, and 39% (11/28) of lagoon-dried sludge samples. lagoon sludge contained detectable viruses (reovirus and enterovirus groups) even after 8 months of retention. because of such prolonged virus survival in sludge, care must be taken in its disposal or utilization.1979311705
[eradication of viral hepatitis of ducklings on farms]. 1979313120
[vaccination of ducklings against pasteurellosis and viral hepatitis]. 1979313121
virus-induced diabetes mellitus. xi. replication of coxsackie b3 virus in human pancreatic beta cell cultures.the capacity of coxsackie b3 virus to infect insulin-containing beta cells was studied in human pancreatic cell cultures. antibody to coxsackie b3 virus was labeled with fluorescein isothiocyanate, and antibody to insulin was labeled with rhodamine. by use of a double-label antibody technique, three populations of cells were identified: uninfected insulin-containing beta cells, which stained only with rhodamine-labeled anti-insulin antibody; coxsackie-infected (noninsulin-containing) cells, whic ...1978350678
[bacterial toxins as cause of sudden infant death (author's transl)].at post-mortems held on cot-death infants, the cause of death can be established as a variety of pathological changes. inflammationin the region of the respiratory tract, in particular in the lungs;infections of the gastrointestinal tract; otitis media; shift of electrolytes-recently also the so-called yellow fat ect., can in association with the data on the anamnesis in many cases, through the assumption of bacterio-enterotoxin poisoning, which takes a different course in infants, to that in o ...1978351356
[viral diarrhea in children]. 1978353691
enteroviruses in human disease. 1978360295
zoster-like eruption due to echovirus 6.a unilateral vesiculobullous eruption associated with fever was seen on the neck, shoulder, and upper part of the chest of a 7-year-old boy. although three dermatomes in all were involved, the lesions resembled herpes zoster. the patient had had varicella in infancy. culture of fluid from several bullae yielded echovirus 6; however, and serum neutralizing antibody to this virus rose in titer from 1:32 to 1:640. it is suggested that echovirus 6 and other enteroviruses may cause a number of vesicu ...1979371385
suppression of aortic elastic tissue autofluorescence for the detection of viral antigen.suppression of aortic elastic tissue autofluorescence was achieved by employing a modification of verhoeff's elastic tissue staining procedure. consquently, coxsackievirus b antigen present in the aortic media was detected by conventional fluorescent antibody staining.1979378909
rocky mountain spotted fever. 1979379780
response of pigs to recent isolates of coxsackievirus b5. 1979398243
picornaviruses: rapid differentiation and identification by immune electronmicroscopy and immunodiffusion.immune electronmicroscopy (iem) was used to identify human picornaviruses rapidly and to differentiate enteroviruses from rhinoviruses. human sera, diluted 10- to 50-fold beyond the neutralisation endpoints for homologous virus, readily agglutinated c-type antigens of seven human picornaviruses. human sera did not react by iem with a control animal picornavirus. by iem after acid treatment, differentiation of a human enterovirus from a human rhinovirus was possible. there was an excellent correl ...1977404426
[growth of coxsackie b viruses in the mouse pancreas]. 1977408446
[a new method permitting the quantitative determination of virus present in surface waters].with a 34% efficiency, not related to the amount of viruses, a simple and inexpensive apparatus allows quantitative recovery of enteroviruses from river-water.1977414852
cytoplasmic localization of the uncoating of picornaviruses. 1979419691
neuronal and oligodendroglial infection by the ww strain of theiler's virus.newborn icr mice were infected by intracerebral inoculation of 10(5.3) ld50 of the ww strain of theiler's virus and examined serially by virologic and ultrastructural methods. maximal titers of 10(6) ld50 developed in the brain by day 8 when 90 per cent of the animals were dead or moribund. the virus first appeared and was most prominent in the thalamus, basal ganglia, and midbrain. it spread from these areas throughout the cortex, brainstem, and spinal cord but spared the cerebellar cortex. bot ...1979423527
[echo-11 virus infection in a 6-month-old infant showing clinical signs of varicella]. 1979424258
[virological research experience with infectious, allergic myocarditis]. 1979425418
analysis of sudden unexpected death in southern ontario, with emphasis on myocarditis.the records of all 2427 autopsies performed at the brantford (ont.) general and paris (ont.) willett hospitals from jan. 1, 1969 to aug. 15, 1978 were reviewed. of the 1299 cases of sudden unexpected death investigated by a coroner almost 28% were due to unnatural causes--violence or poisoning. the main cause of natural sudden death was coronary artery disease, which accounted for 43.3% of all the sudden unexpected deaths. in 20 cases the cause of death was thought to be viral myocarditis, and i ...1979436050
clinical characteristics of the afebrile pneumonia associated with chlamydia trachomatis infection in infants less than 6 months of age.respiratory tract colonization with chlamydia trachomatis commonly occurs in natally acquired chlamydial infection and is sometimes associated with a chronic, afebrile pneumonia that has relatively distinctive clinical characteristics. to further define the frequency and clinical characteristics of lower respiratory tract disease associated with c trachomatis, we grouped 56 infants aged less than 6 months with afebrile pneumonia according to nasopharyngeal shedding of chlamydia and viruses and c ...1979440806
[laboratory studies on igg, iga and igm levels in viral myocarditis]. 1979441009
early-appearing antiviral activity in human tears during a case of picornavirus epidemic conjunctivitis.the clinical, virological, and immunological courses of a laboratory-acquired hemorrhagic conjunctivitis were followed. coxsackievirus type a24 (ca24) was isolated from tears for only two days but from sputum and fecal samples for 20 days. maximal levels of virus were detected in the right eye (10(5.1) 50% tissue culture infective doses/ml) 5-7 hr before conjunctivitis in the right eye, and in feces (10(2.8) 50% tissue culture infective doses/g) and sputum (10(2.5) 50% tissue culture infective d ...1979448191
[diagnostic and epidemiological features of a coxsackie virus epidemic in newborn infants (author's transl)].this report deals with a hospital outbreak of coxsackie virus infections in a neonatal ward. most infections were mild, but one boy died from severe toxicosis. six children had an abnormal ecg. virus was isolated from 3 children, including the fatal case. one virus was coxsackie b5, the two others coxsackie a9. a rise in titre in the neutralisation test with respect to coxsackie b5 virus was found in the sera of 13 patients and to coxsackie a9 virus in a further two cases. four cases were diagno ...1979463044
echovirus 33 replication in human peripheral white blood cells.echovirus 33 isolated from the cerebrospinal fluid of a patient with agammaglobulinemia was shown to replicate in vitro in peripheral leukocyte suspensions from a normal antibody negative donor. replication was demonstrated by use of sequential dilution experiments. washed glass adherent mononuclear cell cultures from a normal antibody negative donor were also capable of supporting echovirus 33 replication in vitro. leukocyte suspensions from the infected agammaglobulinemic patient extinguished ...1979479862
non-polio enterovirus disease in the united states, 1971--1975.reports to the center for disease control on isolation of non-polio enteroviruses for the years 1971--1975 were analysed. during the 5 year period, enterovirus isolations were reported from 7 075 individuals. 90% of these occurred in the 7 month interval of may--november. enteroviruses were isolated more frequently from males than females for all age groups in all 5 years. the incidence of reported isolations decreased with increasing age, and an inverse relationship between severity of disease ...1979489224
susceptibility of inbred mice to chronic central nervous system infection by theiler's murine encephalomyelitis virus.the present study demonstrated that the clinicopathological expression of the late demyelinating disease due to chronic central nervous system infection by theiler's mouse encephalomyelitis virus was dependent, at least in part, on the strain of mouse used as host. a range of involvement was observed, with late disease being most severe in the sjl strain, intermediate in the cba and c3h/he strains, and least in c57bl/6 mice. the lack of clinical signs in seven other inbred strains of mice indica ...1979500211
[variations in resistance of viruses from different groups to chemico-physical decontamination methods].the resistance of a total of 13 different viruses to some important chemico-physical influences was studied under uniform experimental conditions. stability in tape water, thermostability and sensitivity to anodic oxidation, gamma radiation, some virucidal substances and several commercial disinfectants were tested. in evaluating the results, an attempt is made to rank the viruses investigated according to their sensitivity. on average a bovine parvovirus, and also a reovirus and three enterovir ...1979511342
recurrent demyelination in chronic central nervous system infection produced by theiler's murine encephalomyelitis virus.a morphologic study of demyelination produced by theiler's encephalomyelitis virus (tmev) infection in c3h/he mice was performed. demyelination in this strain of mouse was less intense and had a milder gliomesodermal response than that observed in sjl mice. as early as 80 days after infection numerous remyelinated axons were present in c3h/he mice, and later, extensive remyelination was observed and was mainly by schwann cells. about one-third of remyelinated plaques showed recurrent demyelinati ...1979512673
stabilization of "a" particles of coxsackievirus b3 by a hela cell plasma membrane extract.previous studies in our laboratory showed that hela cell plasma membranes were recovered from sucrose gradients in two major bands and that the heavier band possessed a putative inhibitor of uncoating of coxsackievirus b3. it has now been found that the mechanism of inhibition is the stabilization of "a" particles against inactivation at 37 degrees c. [3h]uridine-labeled virions converted to a particles by band 4, the heavier band, were four times more stable at 37 degrees c than those produced ...1979513203
isolation and characterization of temperature-sensitive mutants of echovirus 12. 1979516450
atypical porcine enterovirus encephalomyelitis: possible interraction between enteroviruses and arsenicals.porcine enteroviruses were isolated from weaner pigs that had nervous signs and mild non-suppurative meningoencephalomyelitis and ganglioneuritis. the clinical signs and lesions were not typical of enterovirus infection and it is believed that an organic arsenical present in feed enhanced pathogenicity of enteroviruses. severe non-suppurative polioencephalomyelitis and ganglioneuritis were produced in gnotobiotic pigs by oral inoculation of the viruses.1979539935
[enterovirus 71: epidemiological and clinical aspects]. 1979545573
plasma concentrations of steroid hormones in sows infected experimentally with leptospira pomona or porcine enterovirus strain t1 in late gestation.plasma levels of progesterone, corticosteroids and oestrone were determined during the late stages of pregnancy in four sows experimentally infected with leptospira pomona and in a group of three sows in which fetuses were inoculated in utero with a strain of porcine enterovirus. only one of the seven infected sows farrowed at full term. all fetuses were dead and delivery was prolonged in litters infected with the virus. in the sows with leptospirosis almost all piglets were expelled dead or in ...1977557224
lyophilized combination pools of enterovirus equine antisera: preparation and test procedures for the identification of field strains of 19 group a coxsackievirus serotypes.this paper describes the preparation of seven combination pools of equine antisera, designated j though p, for identification of 19 coxsackievirus a immunotypes. each pool is composed of 4 to 6 antisera; the serotypes included are a1-6, 8, 10-15, and 17-22. these pools, unlike the previously prepared a-h enterovirus pools, were lyophilized from volumes of 0.5 ml dispensed into 5-ml vials, and when rehydrated with 5 ml of diluent provide 50-antibody-unit material ready for use in identification t ...1977558177
[diabetes mellitus and viral infections]. 1977558365
effect of immunosuppression on dengue virus infection in mice.mean survival time following intracerebral inoculation of dengue virus was reduced and the titre of the virus in the brain of immunosuppressed mice was markedly increased. a single dose of cyclophosphamide given 24 h after dengue virus i.c. or i.p. substantially reduced the number of antibody forming cells in the spleen. three doses of dengue virus, each followed by cyclophosphamide 24 h later, produced specific hyporesponsiveness to the dengue virus but not to a heterologous virus (coxsackie b4 ...1977562388
[growth of organ cultures of mouse liver infected with coxsackie a13 virus].peculiarities attending the growth and proliferation of the organ cultures of the liver of mongrel albino mice infected once with coxsackie a-13 virus were investigated. a marked zone of growth, mostly of the epithelial cells, was determined rather early in the liver explants of mice in the experimental group, whereas in control group of mice the cell growth around the explant of the liver was either absent or very weak. besides, a great number of lymphocytes evenly arranged in the zone of hepat ...1978566135
echo 25 focal encephalitis and subacute hemichorea.echo virus 25 focal encephalitis was documented for the first time in a 5-year-old boy with unequivocal hemichorea. hemichorea caused by enterovirus cns disease has never been reported. echo virus antigen in cerebrospinal fluid (csf) cells was demonstrated by the indirect immunofluorescent technique and typed by a significant rise in neutralizing antibodies against echo virus 25. sequential computerized tomographic (ct) studies with digital analysis demonstrated the evolution of a focal process ...1979571566
chronic echo type 5 virus meningoencephalitis in x-linked hypogammaglobulinemia: treatment with immune plasma.a patient with x-linked hypogammaglobulinemia developed chronic meningoencephalitis. echo virus type 5 was repeatedly cultured from cerebrospinal fluid (csf). infusions of high-titer, specific plasma resulted in clinical improvement, but failed to eradicate the virus. after more intensive plasma infusions, the virus could not be cultured from the csf. the patient died 8 months after institution of intensive therapy. the cause of death was unknown. autopsy showed persistence of perivascular and m ...1979572004
[etiopathogenesis of diabetes mellitus--genetic factors]. 1979573523
epidemic of acute haemorrhagic conjunctivitis in freetown, sierra leone, in 1970.epidemiological features of the epidemic of acute haemorrhagic conjunctivitis in freetown, sierra leone, in 1970, are described. on the basis of hospital figures and a house-to -house survey of 0.9% of the population it is estimated that 50-53% of freetown's population suffered from the conjunctivitis in 20 weeks. though no causative agent was isolated, it is supposed, on the basis of the striking similarity with other outbreaks, that the epidemic was caused by enterovirus type 70. hospital figu ...1979575380
effect of an enterovirus in gilts inseminated with a semen-virus mixture. 1977576523
observations on virological studies in indian childhood cirrhosis. 1977591014
[encephalomyelitis of atypical course probably caused by echovirus 7].the authors report a cases of encephalomyelytis caused probably by echo7 virus which was isolated from the cerebrospinal fluid after 45 days of disease. during 120 days 4 relapses of the disease were observed associated with severe general and neurological signs and cerebral coma which ultimately was the cause of death.1977593511
[isolation of a coxsackie b6 virus from a brain biopsy during an encephalitic syndrome]. 1977593848
[clinical aspects in an epidemic focus of coxsackie b4 virus infection]. 1977594524
[studies of an epidemic episode of serous meningitis caused by echo-virus 30].the authors report an outbreak of echo 30 aseptic meningitis occurred in marche and umbria countries from november 1975 to june 1976. the clinic, epidemiologic characteristics and the serological and virological results of 28 cases are discussed.1977597392
[enteroviral gastroenteritis of swine]. 1977602002
enterovirus associated sporadic cases and epidemics. 1977603265
pancreatitis and altered glucose tolerance in mice infected with coxsackie b4 virus.cd1 mice infected with coxsackie b4 virus showed an early polymorph infiltration of the pancreas, which later changed to a mononuclear exudate. a state of glucose tolerance developed concurrently and both events coincided with the inhibition of migration of spleen cells in the presence of the virus. the relevance of these findings to human juvenile-onset diabetes mellitus is discussed.1977605742
interaction of coxsackievirus b-3 and peritoneal exudate cells of adult mice treated with cyclophosphamide.interaction of coxsackievirus b-3 with peritoneal exudate cells (p.e.c.) of adult mice treated with cyclophosphamide (cp) and of normal untreated mice were examined. the measurement of virus concentration in the supernates and the infective center assay of the virus-treated p.e.c. showed no significant differences in viral uptake between the p.e.c. of mice treated with cp for 1 and 24 hours, and the cells of normal untreated mice. however, a significant decrease in viral uptake was found in p.e. ...1977609028
[potential virostatics. 2. s-triazolo[4,3-a] quinoxaline]. 1977609587
[epidemiological studies after an outbreak of meningitis (author's transl)].the outbreak of meningitis during the period from the end of august to the beginning of october 1974 in kiel affected 45 children, particularly those in the age group between 4 and 9 years. an potential causative agents echo viri were identified in 15/45 cases and coxsackie b viri in 2/45 cases. the patients presented the typical meningitic symptoms (fever, headache, stiffness of the neck). in all cases the disease ran a benign course. - epidemiologically, it was possible to trace 32/45 cases ba ...1977610256
[viral infection, autoimmunity and immunogenetics in insulin-dependent diabetes mellitus]. 1977612059
a new model of persistent viral infection with primary demyelination.theiler's encephalomyelitis virus (tmev) in mice represents one of the few existing animal models of virus-induced demyelination and may provide further information about the human disease, multiple sclerosis. an inbred strain of mice (sjl/j) employed in the present ultrastructural study, develops a life-long neurologic illness characterized by profound spasticity after intracerebral inoculation of tmev. anesthetized animals were sacrificed sequentially by total body perfusion with gluteraldehyd ...1977616547
[viral meningoencephalitis: late development].two years ago, we performed a precocious evolutive eeg study of a specimen not selected from the virus me to echo 4 burst (cepa prima) late 1972 to early 1973 (6). some time between the appearance of the first symptoms and the 8 weeks following, alterations of cerebral electrogenesis became manifest in this study. these alterations disappeared or dimished in significance in the more tardy outlines: focalization tendency, tendency to change from "suffering" to "irritative" aspect. during this yea ...1977616553
[complex action of an electrical current and sodium hypochlorite on viruses in water]. 1978627376
the behaviour of f2 coliphage in activated sludge treatment.a model activated sludge treatment plant was used which was functionally very similar to a full-scale plant. it was inoculated with f2 coliphage and the titres of virus in the influent, the mixed liquor and the effluent were monitored regularly. the distribution of the virus in the solids and liquid fractions of the mixed liquor was in the ratio of 18:82 and 20.4% of the influent virus was recovered in the effluent. after inoculation was stopped the titre of virus in the solids fraction of the m ...1978632563
experimental coxsackie virus b-3 and b-4 myocarditis in mice.mice were inoculated with recently isolated coxsackie virus b-3 and b-4 intraperitoneally. severest lesions in the hearts were observed in mice between the age of 7 and 14 days. grossly yellow-white patches were seen on the hearts of mice from the 7th day to the 6th month after virus inoculation. microscopically, the heart showed extensive myocardial necrosis, inflammation with small mononuclear cells and calcification on the day of 7. there were myocardial fibrosis and calcification at the 6th ...1978633597
[membrane potential of the host cell in the process of viral interaction with the cell]. 1978634166
[possible methods of control of virus disease in swine today and in the future. ii. specific applications (author's transl)].the four alternatives discussed in the previous paper (5), are applied to a number of virus infections which are common in pigs. the enzootic state of smedi enteroviruses, vomiting and wasting virus and parvovirus should be promoted by bringing the young gilts into close contact with the older sow population at a sufficiently early stage. there should preferably not be a change of herd for primiparous sows during pregnancy. in parvovirus infection, maternal immunity may be so prolonged that gilt ...1978653695
juvenile onset diabetes mellitus in pregnant women: failure to associate with coxsackie b1-6, mumps, or respiratory syncytial virus infections. 1978660368
optimal conditions for plaque assay of echoviruses in human embryonic lung fibroblast cells.the present paper gives optimal conditions for plaque assays tn human embryonic lung fibroblast cells with 45 echoviruses including 11 fresh isolates, covering 31 serotypes. all the viruses tested except echovirus type 23 produced plaques at a high titer in the same cells by the methods described in this communication. plaque formations by a number of strains were markedly enhanced in size or number or both by the addition of polycation.1978661010
characterization of a regulator of host cell permissiveness to a specific enterovirus. 1978664223
the long term complications of viral illness. 1978666663
[production of interferon and virus-neutralizing antibodies in adult mice infected with enteroviruses during the neonatal period].newborn albino mice were inoculated with enteroviruses and in 6 weeks reinfected with homologous or heterologous strains. strains moderately pathogenic for newborn mice led to formation of specific immunologic memory. mice infected after birth with highly pathogenic strains produced specific antibodies for a long time and lacked secondary response. production of interferon was not associated either with the strain pathogenicity for newborn mice or with the presence of antibodies.1978667327
[inactivation of coxsackie group viruses in sodium hypochlorite]. 1978669366
broad specificity of gastrointestinal antibodies following vaccination of piglets with a porcine enterovirus. 1978670445
[acute respiratory infections in summer associated with non-poliomyelitis enteroviruses]. 1978674957
[coxsackie a13 virus in the etiology of various cardiopathies in childhood]. 1978676475
the clinical presentations of rocky mountain spotted fever. comments on recognition and management based on a study of 63 patients.rocky mountain spotted fever continues to increase in the united states and the case-fatality ratio remains unchanged despite the availability of effective antibiotics. the apparent reason for the continuing deaths from this disease is the failure of physicians to consider the diagnosis in patients presenting with febrile exanthems in the late spring and summer months. a clinical diagnosis should be based on the history of tick exposure and the presence of fever and the typical exanthem. serolog ...1978679582
neonatal herpangina caused by coxsackie a-5 virus. 1978690774
[polio-like radiculomyelitis complicating acute hemorrhagic conjunctivitis]. 1978691496
enteroviral meningitis: a reappraisal. 1978693167
[clinico-immunological characteristics of cardiac lesions in chronic tonsillitis]. 1978705658
[echo type 30 virus as the etiological agent of meningitis in 1975 in warsaw]. 1978715232
structure and replication of echovirus type 12. 1. analysis of the polypeptides and rna of echovirus 12 particles.the propagation of echovirus 12 in green monkey kidney (gmk) cells, a continuous cell line, is described. virions and empty capsids are purified to homogeneity by cscl density and by velocity centrifugation. the protein composition of the particles as compared to poliovirus 2 particles is analyzed by dodecyl sulfate/polyacrylamide gel electrophoresis. infectious virions were found to be composed of four different polypeptide chains of molecular weights 33,000, 31,000, 24,000 and 7,000. some addi ...1978729593
structure and replication of echovirus type 12. 2. viral polypeptides synthesized in the infected cell.a technique has been devised which allows us to label predominantly echovirus-12-specific proteins: upon infection in the presence of d-(--)-2-(alpha-hydroxybenzyl)benzimidazole plus actinomycin d the shut-off of host-cell protein synthesis takes place as in infected, untreated cells, but the bulk of viral protein synthesis is inhibited. upon removal of 2-(alpha-hydroxybenzyl)benzimidazole a peak of viral protein synthesis is visible 3 h later. the time course of appearance of viral proteins is ...1978729594
epidemiology of enterovirus infections in children in nagpur. 1978730226
congenital tremor in pigs in sweden. a case report.the authors describe an outbreak of congenital tremor in piglets in a herd for the integrated production of fattening pigs. all sows farrowing within a period of slightly over a month gave birth to piglets affected to a varying degree. all the sows were of the swedish land race and covered by boars representing two different lines not genetically related to each other. the case history comprised information on oral treatment of the sows with an antiparasitic trichlorfon compound (neguvon) during ...1978733481
paralytic poliomyelitis in the gaza strip and west bank during recent years.numerous cases of paralytic poliomyelitis occurred during epidemic years and in interepidemic periods in recent years in the gaza strip and the west bank. during the epidemics of 1974 and 1976, more than 100 paralytic cases were recorded each year. the dominant poliovirus was type 1. in interepidemic years, especially in the gaza strip, type 3 poliovirus was the prevalent type. the age group affected were infants and children up to 3 years and 50% of cases occurred during the first 12 months of ...1978753648
myocarditis caused by echo type 11 virus. 1978757013
antigenicity and polypeptide composition of native and heated echovirus type 7 procapsids.the native procapsid (naturally occurring empty capsid) of echovirus type 7 (e7) possesses n-antigenicity, which is as highly strain-specific as the native virion. when the native procapsid is heated, its antigenicity is converted to h-antigenicity which is common among strains of e7 and thus type-specific. however, no difference was detected in the sedimentation rate (80s) and polypeptide composition (vp0, 1 and 3) of the native and heated procapsids.1979759555
[the mechanism of plaque production by enteroviruses under bentonite overlay. relationship between plaque production and the dynamics of intracellular virus reproduction and membrane potential of the host cell].the association of plaque production under bentonite overlay with the cycle of intracellular reproduction of enteroviruses and the dynamics of the membrane potential of infected cells was studied. it was shown that by the time of termination of the intracellular enterovirus reproduction cycle (4 1/2-5 hours postinfection) bentonite particles were torn away from the cell surface. at the same time the membrane potential of the host cell began to decline progressively. the data obtained explain the ...1975769340
Displaying items 701 - 800 of 12545