| [chimpanzee as a pet: cause of a shigella infection]. | | 1979 | 372831 |
| [properties of the r plasmids of sh. flexneri strains isolated in bulgaria]. | the study of 3,237 sh. flexneri strains isolated in bulgaria revealed that 50.72% of them were resistant to antibiotics. 95.88% of the antibiotic-resistant strains were found to have r factor of incompatibility groups f, i or n. the plasmids of incompatibility group f had the property fin+, and the plasmids of groups i and n had the property fin-. r plasmids were divided into 4 groups by their ability for phage restriction. | 1979 | 373338 |
| [comparative evaluation of different globulin preparations and of the means for blood sensitization in obtaining antibody erythrocytic diagnostica]. | in comparing the hemosensitizing activity of various immunoglobulin preparations with different methods of erythrocyte loading the greatest activity and specificity was revealed in igg isolated by means of deae-sephadex a-50. the method of erythrocyte sensitization with the use of alizarin blue indicator was more advantageous in respect to sensitivity and specificity of sh. sonnei and newcastle indication over boyden's, jandl and simmons', bing's methods. | 1979 | 373342 |
| [antibiotic resistance of shigella in different regions of the ussr]. | shigella were most sensitive to polymyxin ceporin, ampicillin, neomycin and furazolidone and resistant to chloramphenicol, tetracycline and streptomycin. shigella resistant simultaneously to two or three drugs mainly to tetracycline + chloramphenicol, tetracycline + streptomycin and tetracycline + chloramphenicol + streptomycin were most frequent. the frequency of the shigella strains carrying r-plasmids increased from 28 per cent in 1969--1970 to 72.6 per cent in 1977. the shigella strains isol ... | 1979 | 373617 |
| studies on virulence of shigella flexneri. | the antigenic structure and some biological properties were compared in virulent s. flexneri strains of differences in: 1) antigenic composition; 2) biochemical activity; 3) sensitivity to a set of shigella phages and 4) susceptibility to phagocytosis. the only difference found concerned the ld50 for mice; it was 10 to 100 times larger for avirulent than for virulent strains of s. flexneri. the toxic products of the strains were also compared. the lipopolisaccharide and free endotoxin purified f ... | 1978 | 373685 |
| macrophage fatty acid composition and phagocytosis: effect of unsaturation on cellular phagocytic activity. | in order to manipulate the physical properties of the macrophages membrane, methods were developed which potentiated the incorporation of exogenously supplied fatty acids into membrane lipids. chromatograms of macrophages which were grown in the presence of a variety of fatty acids demonstrated that exogenously supplied unsaturated fatty acids (palmitoleic, oleic, elaidic, linoleic, linolenic and arachidonic acids) were readily incorporated into the cells and selectively altered the fatty acyl c ... | 1979 | 374248 |
| protein and ribonucleic acid syntheses in heat-damaged and heat-killed escherichia coli. | protein and ribonucleic acid (rna) syntheses were measured in both lethally injured and thermally damaged viable cells after heating at lethal temperatures. immediately after heating, cells were incubated in growth media containing either [14c]leucine or [3h]uracil. the labeled cells were subsequently treated with penicillin. viable cells were shown to lyse, and the intact nonviable cells were collected by centrifugation. the results showed that after heating, protein and rna synthesis were rein ... | 1979 | 374390 |
| non-random distribution of transduction termini in transductants from the integrated r plasmid, r100-1. | tra+ and tra- derivatives of drug resistance plasmid, r100-1, were isolated by phage p1 from an hfr donor with integrated r100-1 and then analyzed by complementation tests with tra- point mutants of flac. tra+ derivatives of r100-1 carrying tetracycline resistance alone and those carrying all six drug-resistrance genes could support transfer of tra- point mutants of flac except flac traj, whereas all of tra- derivatives of r100-1 failed to complement any one of tra- point mutants of flac. this s ... | 1979 | 375027 |
| shigella vaginitis: report of 38 patients and review of the literature. | thirty-eight cases of shigella vaginitis were identified in a retrospective review of records kept over the past 14 years. the cases of vaginitis were due to three subgroups of shigella. vaginitis varied in severity and duration, persisting for several months in some instances. in 47% of the cases, there was associated bloody vaginal discharge. only two children had diarrhea temporally associated with vaginitis, but six others had had diarrhea. many treatment modalities were used. systemic antib ... | 1979 | 375177 |
| nucleotide sequence of the transposable dna-element is2. | the complete sequence of the transposable dna element is2 in gal op-308:: is2 (i) has been determined. this element is 1.327 bp long. the integrated element is flanked by a five base pair long sequence duplication. the termini of is2 are not perfect inverted repeats, but a close approximation. | 1979 | 375194 |
| bacteremia caused by shigella flexneri. | | 1979 | 375454 |
| [conjugative r plasmids of enterobacteria]. | | 1979 | 375629 |
| [interrelationship between the serum lysozyme level and the leukocyte count in sonne and flexner dysenteries]. | interrelation between the level of the serum lysozyme and the count of the leucocytes, as well as the severity of the disease was found in testing of the peripheral blood of 133 patients with acute sonnei and flexner dysentery. it is recommended to use the lysozyme index in the clinical practice as one of the additional criteria for estimation of the severity of acute dysentery. | 1979 | 375827 |
| shigella serotypes in recent isolations at lucknow. | | 1979 | 376439 |
| further studies on the activation of lymphocytes by endotoxin protein. | endotoxin protein, an outer membrane protein of gram-negative bacteria associated with lipopolysaccharide endotoxin, has been found to be a potent activator of lymphocytes. in the absence of t lymphocytes and macrophages, endotoxin protein can stimulate murine b lymphocytes to synthesize dna and produce antibodies of diverse specificities. this stimulation is greater than that obtained with two well known murine b cell activators, lipopolysaccharide endotoxin or ppd-tuberculin. splenic lymphocyt ... | 1979 | 376715 |
| quantitative determination of titers of anti-zona serum. | the titers of rabbit antiserum against isolated mouse zonae pellucidae were examined by several methods in connection with inhibitory effect on fertilization. the titers determined by zona precipitate, zona dissolution, indirect immunofluorescence and in vitro fertilization tests were 2(4), 2(1) to 2(4), 2(7) and 2(4), respectively. cytotoxic effect could not be detected from zona antibody. the indirect immunofluorescence was most sensitive for detection of zona antibody but did not represent th ... | 1979 | 376778 |
| composition of isolated edema fluid in cold-induced brain edema. | edema fluid isolated from cats with cold-induced brain edema was subjected to analysis of electrolyte content, enzyme activities, colloid osmotic pressure and the radioactivity of intravenously injected 99mtc-labeled albumin. the findings corroborate the essential features of vasogenic edema, such as its origin from the blood plasma, its rapid propagation into the white matter of the brain as contrasted with the delayed spread into gray matter, and its contribution to composition of cerebrospina ... | 1979 | 376787 |
| [storage of shigella flexneri with virulence preserved]. | | 1979 | 376977 |
| [parenteral use of a therapeutic vaccine in acute dysentery]. | | 1979 | 377515 |
| [analysis of merodiploid strains of sh. flexneri that have lost virulence]. | episome f'13 introduced into the genome of a virulent sh. flexneri strain brought about changes in a number of properties of the recipient strain. the expression of these properties was not connected with the chromosome area allelic to the plasmid genome. these changes seem to be induced by the mobilization of the chromosome genes of e. coli. the loss of virulence in sh. flexneri strains carrying episome f'13 seemed to be the consequence of two reasons: the overlapping of kcpa gene by its domina ... | 1979 | 377868 |
| [search for host specificity systems in shigella using dd-series phages]. | a total of 712 shigella strains were studied with the use of dysentery diagnostic phages dd ii, dd vi and dd vii in order to reveal the systems of host dna specificity. the study comprised 4 tests: mass screening by the intensity of phagolytic reaction of phages in various strains; and the determination of the parameters of adsorption. as a result, an effective modification and restriction systems were revealed in sh. sonnei 311 with the use of phage dd ii. bacteriophage dd vii was effectively r ... | 1979 | 377869 |
| [dynamics of the change in sensitivity of shigellae to gentamycin and cephaloridine in vitro]. | the dynamics of the changes in the shigella sensitivity to gentamicin and cephaloridin was studied in vitro using liquid nutrient media with gradually increasing concentrations of the drugs. 50 passages were performed. it was found that shigella flexner and sonnei decreased their sensitivity to gentamicin to a little extent and remained middle sensitive. sensitivity of shigella flexner to cephaloridin also changed to a little extent, while shigella sonnei became moderately resistant. | 1979 | 378113 |
| [level and nature of the drug resistance of shigella flexneri]. | characteristics of antibiotic resistance of 300 strains of shigella flexner 2a isolated from patients within 1976--1977 in the regions where these bacteria were very rare for a long period of time were studied. it was shown that most of the isolates were resistant to chloramphenicol (88.1 per cent), tetracycline (94.8 per cent), streptomycin (89.1 per cent), polymyxin m (82.4 per cent) and others. 46.5--61.6 per cent of the isolates were resistant to neomycin antibiotics. a high level of the res ... | 1979 | 378114 |
| vivo clearance of enteric bacteria from the hemolymph of the hard clam and the american oyster. | american oysters, crassostrea virginica, and hard clams, mercenaria mercenaria, were experimentally contaminated with escherichia coli, salmonella typhimurium, and shigella flexneri either by intracardial injection or via the natural route of ingestion. bacterial inactivation in the hemolymph was monitored for 72 h after exposure to these enteric pathogens at 20 and 6 degrees c. at 6 degrees c, both mean bacterial uptake by ingestion and subsequent clearance was singificantly lower that at 20 de ... | 1979 | 378127 |
| infectious mononucleosis associated with fatal beta hemolytic streptococcal infection. | | 1979 | 378507 |
| enzyme-linked immunosorbent assay for immunoglobulin g and immunoglobulin a antibodies to shigella flexneri antigens. | an enzyme-linked immunosorbent assay has been developed to detect class-specific antibodies to shigella flexneri lipopolysaccharide antigens. this enzyme-linked immunosorbent assay system has been used to measure antibodies present in serum or intestinal secretions without further purification. it is considerably more sensitive than passive hemagglutination, allowing detection of as little as 1.3 ng of specific immunoglobulin g antibody per ml in immune sera. optimal conditions for this assay ar ... | 1979 | 378853 |
| molecular characterization of plasmids from virulent and spontaneously occurring avirulent colonial variants of shigella flexneri. | spontaneous transition of shigella flexneri from t- to o-type colonies with concomitant loss of virulence dose not appear to be accompanied by a change in any of the four plasmic species found in the virulent parent. | 1979 | 378861 |
| monocyte function in psoriasis. | monocytes derived from the peripheral blood of psoriatic patients demonstrated a significantly higher phagocytic capacity (36 to 40%) for both 125i-labeled shigella flexneri and 125i-labeled staphylococcus albus compared with monocytes from healthy subjects. monocytes from psoriatic patients showed a 2-to-4fold increase in bactericidal capacity against s. albus when compared with normal monocytes. however, the bactericidal capacity of monocytes from diphylline-treated patients did not differ fro ... | 1979 | 379240 |
| [a dysentery epidemic among tunisia travelers]. | | 1979 | 379657 |
| [effect of metabolism products of shigella sonnei, sh. flexneri and sh. shigae on proteolytic activity of the organism connective tissue]. | the activity of proteolytic enzymes, neutral proteinases and cathepsins e+d, was determined in homogenates from the tissues of capsules formed around diffusion chambers with shigella (shigella sonnei, sh. flexneri, sh. shigae) 1, 2, 3, 5 and 10 days after their implantation to the abdominal cavity of rabbits. the specific proteolytic activity in the capsule tissues in the experimental variants is higher in all the studied periods than in the control and its singularities depend on the microbe sp ... | 1979 | 380094 |
| [sh. flexneri population heterogeneity according to the cellular fatty acid makeup]. | the composition of fatty acids in the cells of 100 clones of sh. flexneri, strain 9054, isolated from a dysentery patient was studied by the method of gas chromatography. fatty acid composition in 75 clones was similar to the fatty acid composition of the initial culture: 25 clones differed to a variable degree from the prevailing group of clones in the content of unsaturated and cyclopropane fatty acids and, to a considerably lesser extent, in the content of palmitic acid and a number of other ... | 1979 | 380239 |
| [data to substantiate the early immunological diagnosis of dysentery]. | the interaction of the whole blood from patients with dysentery and gastrointestinal diseases of non-dysenteric etiology, with the causative agents of dysentery, sh. sonnei and sh. flexneri, and saprophytic, staphylococci labeled with radioactive isotopes was studied in vitro. in dysentery an increase in the capacity of the blood for shigella fixation was observed from the beginning of the disease. during the 1st week of the disease this reaction was strictly specific and accompanied by a decre ... | 1979 | 380241 |
| [course of dysentery and the specific alteration of the neutrophils in children in the use of monomycin and a diet with an increased protein content]. | acute dysentery mainly due to shigella sonnei and dynamics of the neutrophil damage index (ndi) of the blood were studied in 80 children at the age of 1 to 14. 20 children (group 1) were treated with monomycin under conditions of a diet with an excessive content of protein (by 25% higher than the physiological norm). 60 children or 3 groups of 20 children each were not subject to such conditions and were considered as control groups. reduction in the time of recovery (by 4 days) and bacteriologi ... | 1979 | 380456 |
| study on the possible entry of bacterial endotoxin and prostaglandin e2 into the central nervous system from the blood. | 1 a study has been made of the possible entry of 51cr-bacterial endotoxin and [5,6,8,11,12,14,15(n)-3h]-prostaglandin e2 ([3h5-pge2) into the cns of the anaesthetized cat. 2 no radioactivity was detected in perfusates of the preoptic-anterior hypothalamus or in the cerebrospinal fluid (c.s.f.) in vivo, or in brain tissue post mortem following intracarotid infusion of 51cr-bacterial endotoxin. 3 intracarotid administration of [3h]-pge2 resulted in the entry of radioactivity into the cns of endoto ... | 1979 | 380709 |
| age-dependent macrophage functions in new zealand black mice. | | 1979 | 380820 |
| somatic antigens of shigella. the structure of the specific polysaccharide of shigella newcastle (sh. flexneri type 6) lipopolysaccharide. | the specific polysaccharide was obtained from the lipopolysaccharide of shigella newcastle by mild acid hydrolysis and further purified by permeation chromatography on sephadex g-50. it was found to consist of l-rhamnose, 2-acetamido-2-deoxy-d-galactose, d-galacturonic acid residues and o-acetyl groups in the molar ratios of 2:1:1:1. on the basis of 1h and 13c nuclear magnetic resonance spectroscopy, methylation analysis, partial acid hydrolysis, smith degradation, and chromium trioxide oxidatio ... | 1979 | 381001 |
| shigella infection of henle intestinal epithelial cells: role of the bacterium. | epithelial cell infection by shigella flexneri 2a was studied in an in vitro model system. using the henle 407 human intestinal epithelial cell line as host cells, a standardized experimental protocol which allowed quantitative measurement of infection was developed. intravellular residence of infecting organisms was confirmed by indirect fluorescent-antibody staining of unfixed and methanol-fixed (henle 407) cells and by quantitative bacteriological culture of disrupted host cells after infecti ... | 1979 | 381204 |
| [diagnosis of acute appendicitis in patients suffering from diarrhea]. | | 1979 | 382628 |
| enterotoxin production by shigella flexneri type 2a, strain no. m42-43. | enterotoxin produced by shigella flexneri type 2a, strain m42-43, is similar to "shig-like" cytotoxic enterotoxin and shares common features with that of other s. flexneri strains. on the basis of molecular filtration and neutralization experiments it is suggested that the same molecule carries these biological characters. | 1978 | 382758 |
| phenylalanyl-trna synthetase induced conformational change of escherichia coli trna phe. | | 1979 | 383142 |
| salmonella phage glycanases: substrate specificity of the phage p22 endo-rhamnosidase. | interaction between phage p22 and phenol-water extracted lipopolysaccharides from sensitive salmonella bacteria belonging to serogroups a, b and di results in hydrolysis of the alpha-l-rhamnosyl linkages within the tetrasaccharide repeating unit of the o-antigenic polysaccharide chain. these o-antigens have identical structures except for the nature of the 3,6-dideoxy-hexosyl group linked to o-3 of the d-mannosyl residue. removal of the dideoxysugar, or periodate oxidation followed by borohydrid ... | 1979 | 383902 |
| [humoral factor study of natural immunity in sonne and flexner dysenteries]. | | 1979 | 386651 |
| [seasonal problems of bacterial dysentery in the dagestan assr]. | during the period of 1959-1973 bacterial dysentery showed high morbidity rate in daghestan in all seasons, this tendency existing both in urban and rural areas. the peculiarity of the monthly distribution of dysentery cases, observed all over the repulic, was the shift of the morbidity peak from august to september-october, and in some years even to november; this could be clearly observed from the analysis of the material as a whole and from the analysis of dysentery morbidity rates in rural an ... | 1979 | 386661 |
| [transduction analysis of the genetic control of synthesis of the r-nucleus of the lipopolysaccharide of o-antigen]. | | 1979 | 386667 |
| transfer of f'lac+ plasmid from salmonella typhimurium to shigella flexneri. | | 1978 | 387348 |
| the enzymes of the galactose cluster in saccharomyces cerevisiae. purification and characterization of galactose-1-phosphate uridylyltransferase. | | 1979 | 387754 |
| synthesis and properties of fluorescent nucleotide substrates for dna-dependent rna polymerases. | a new class of fluorescent nucleotide analogs which contain the fluorophore 1-aminonaphthalene-5-sulfonate attached via a gamma-phosphoamidate bond has been synthesized. both the purine and pyrimidine analogs have fluorescence emission maxima at 460 nm. cleavage of the alpha-beta-phosphoryl bond produces change in both the absorption and fluorescence emission spectra. the fluorescence of the pyrimidine analogs is quenched; cleavage of the alpha-beta-phosphoryl bond of the utp analog produces abo ... | 1979 | 387781 |
| api and minitek systems in identification of clinical isolates of anaerobic gram-negative bacilli and clostridium species. | a comparison of the api and minitek methods of biochemical testing was made on a variety of anaerobic bacteria. although api and minitek results were not compared to more standardized or conventional procedures of identification, multiple repeat testing of the two systems was done on routine clinical isolates and known organisms to determine (i) whether the reactions were reliably consistent, (ii) the ease of reading the two systems with respect to the frequency of questionable results, and (iii ... | 1979 | 387809 |
| characterization of plasmids from antibiotic-resistant shigella isolates by agarose gell electrophoresis. | gel electrophoresis of dna from 95 clinical isolates of shigella sonnei and shigella flexneri resistant to antibiotics revealed a heterogeneous plasmid population. most of the plasmids were smaller than 6 megadaltons (mdal). six s. sonnei isolates with the most common antibiotic resistance pattern were characterized. they had two plasmids in common: one was a self-transmissible fi+ plasmid of 46 mdal encoding resistance to streptomycin and sulphafurazole. in addition, several cryptic plasmids ra ... | 1979 | 387914 |
| [clinical and pathogenetic comparisons with allergization in flexner and sonne dysentery]. | | 1979 | 388063 |
| [comparative characteristics of the clinical course of flexner and sonne dysenteries during the warm and cold periods of the year]. | | 1979 | 388064 |
| [comparative effectiveness of the treatment of acute dysentery]. | | 1979 | 388065 |
| shigella dysenteriae, sh flexneri, and sh boydii infections in england and wales: the importance of foreign travel. | | 1979 | 389342 |
| macrophage functions in high and low cancer incidence strains of mice. a comparative study. | | 1979 | 389688 |
| [structure of drug resistant bacilli (author's transl)]. | | 1979 | 390191 |
| human plasma angiotensinogen: a review of purification procedures. | the current status of the purification and characterization of human angiotensinogen is reviewed. one problem encountered in the past has been the copurification of a protein with similar porperties. this protein has tentatively been designated alanine-protein. an efficient separation of angiotensinogen and alanine-protein was obtained on a zinc chelate column. alanine-protein has been purified and its amino acid and carbohydrate composition determined. the cooh-terminal amino acid and the nh2-t ... | 1979 | 390363 |
| [cyclical nature and the prediction of the dynamics of the epidemic process in different types of dysentery]. | | 1979 | 390937 |
| patterns of shigella species and serotypes in east africa. | | 1979 | 391541 |
| [intestinal flora and bile acids metabolism -- influence of bile acids on rejection of shigella flexneri 2a from the intestine (author's transl)]. | | 1979 | 392126 |
| [effect of intercurrent pathology on the immune response of the child's body in dysentery]. | | 1979 | 392428 |
| [characteristics of the outbreak and control of an epidemic of bacillary dysentery of hydric origin]. | in december 1978, an unexpected outbreak of acute gastroenteritis occurred in a shoe factory. the clinical, epidemiological and laboratory investigations established the hydric origin of the dysentery due to shigella flexneri 3 a, caused by the illicit communication of the drinking water and industrial water mains. the antiepidemic measures promptly taken arrested the outbreak in three days ; there were no secondary, contact cases. | 1979 | 394270 |
| [studies concerning dysenteric infections in a closed children's community before and after antidysenteric vaccination. i. epidemiological considerations on acute intestinal infections]. | in the closed children's community studied between 1 jan. 1976 and 13 june 1977, a high proportion (54%) of the total number of acute intestinal infections was of dysenteric etiology, i.e. 46,9% in the 0--1 year age-group and 21,1% in the 1--3 years age-group, the dominant shigella subtype being represented by shigella flexneri 2a (25.1%). as only 37.2% of the total number of dysentery cases were manifested by enterocolitis and a high proportion (33.3%) ran a chronic course, the disease was not ... | 1979 | 394271 |
| lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate. | rabbit neonates delivered on day 27--30 of gestation were subjected to intermittent positive pressure ventilation (ippv) for 60 min. tidal volume was standardized to 10 ml/kg, and the insufflation pressure required to maintain this tidal volume was recorded. the quasistatic compliance of the lung-thorax system, corrected for variations in body weight, was significantly lower in animals delivered on day 27--28 than in those delivered on day 29--30. immature animals with low lung-thorax complianc ... | 1979 | 394314 |
| [shigellosis in tananarive (madagascar). ii : bacteriologic and therapeutic features (author's transl)]. | in acute dysenteries or diarrhoeas shigellae are the bacterial organisms which are the most frequently isolated from coprocultures. the most frequent sub-group is sub-group b (s. flexniri). in vitro, shigellae are sensible to all antibiotics but often resistant to sulfamids. treatment is not difficult. | 1979 | 395407 |
| the cellular and humoral immune response after administration to the guinea pig of shigella flexneri 2a t32--istrati vaccinal strain by different routes. | | 1978 | 395927 |
| antigenic similarity of morphologic type ciii1 bacteriophages. | | 1979 | 397728 |
| phagocyte functions in familial mediterranean fever. | monocytes derived from peripheral blood of patients with familial mediterranean fever (f.m.f.) demonstrated lower phagocytic capacity for shigella flexneri and depressed bactericidal activity against s. albus when compared to monocytes from healthy individuals. treatment of patients with colchicine did not alter these functions. on the other hand, chemokinesis of pmn of f.m.f. patients was enhanced especially during attacks. colchicine treatment decreased significantly the pmn chemotactic migrat ... | 1979 | 397753 |
| comparison of some shigella flexneri (escherichia coli) hybrids in cross agglutination and agglutinin absorption tests. | antigenic structure of lac+ hybrids selected from escherichia coli x shigella flexneri crosses was compared in the cross agglutination and absorption tests. identity of the hybrids from the recipients of serotype 2a and variant y was proved, as well as from serotypes 1b and 4b. the latter hybrids were coupled with shigella flexneri strains 3a, 3b and 3c. the hybrids appeared almost identical with serotype 3c. | 1979 | 398206 |
| histoautoradiographic investigation of the invasive dissemination of ehrlich ascites tumor cells through the organs of the mouse. | in this paper the attempt has been pursued to quantify by a well planned experimental technique the ability of the neoplastic cells to spread around in vivo through various organs of laboratory animals. by making use of the histoautoradiographic techniques the incorporation of 3h thymidine either by the normal and by the neoplastic cells has been investigated at many different anatomical sites in ehrlich ascites tumor-bearing mice. the method has been shown to be well suited also for the quantit ... | 1979 | 398216 |
| the intestinal flora and infant botulism. | the intestinal flora of experimental animals interferes with infection by species of salmonella and shigella. protection against infection with these organisms appears to be related to high concentrations of volatile acids, low ph, and low oxidation-reduction potential of the intestinal contents of animals with an intact flora. there are no data to show that the flora influences colonization of the intestine with clostridial species, but indirect evidence suggests that the intestinal flora may b ... | 1979 | 399374 |
| colonization by salmonella typhimurium and shigella flexneri iii of the gastrointestinal tract of mice treated with beta-2-thienylalanine and streptomycin. | mice fed beta-2-thienylalanine (beta-2-t) by oesophageal tube were no more susceptible to gastrointestinal tract colonization by salmonella typhimurium or shigella flexneri iii than control mice fed water. in both beta-2-t-fed and water-fed groups, the increasing dosage of s. typhimurium, in logarithmic increments to groups of mice, resulted in increasing numbers of these bacteria detectable on dilution plates from organ homogenates. colonization by s. flexneri iii only occurred at a dosage of 1 ... | 1979 | 399720 |
| [research methods of r factors (author's transl)]. | after having outlined the routine methods for the study of drug resistance plasmids used at highly specialized centres such as the london enteric reference laboratory, the aa. examine the most practical methods of a pure and simple way of discovering r factors in enterobacteria. a brief reference is made to some of the in vivo transfer techniques before reducing the various possibilities of in vitro survey to essentials. the experimental conditions realized by some aa. for mating in liquid media ... | 1979 | 400251 |
| [drug resistance of shigella strains isolated in central italy during 1969-1976 (author's transl)]. | only ninety-three strains of shigella, eightyseven of which have been identified as s. sonnei and six as s. flexneri were collected during 1969-1976 at the pathogen enterobacteria centre of pisa in central italy, as evidence of an epidemiological situation marked by a rare occurrence of syndromes related to these organisms. the collected strains were tested with disks of nine antibacterial drugs in common use: the survey detected sensitivity of all the strains to cephaloridine, ampicillin, carbe ... | 1979 | 400254 |
| resistance to lyophilization of salmonella typhi, escherichia coli and shigella flexneri strains. | | 1979 | 400513 |
| shigellae and reiter's syndrome. | | 1979 | 400766 |
| the role of cellular locomotion in leukemic infiltration. an organ culture study on penetration of l 5222 rat leukemia cells into the chick embryo mesonephros. | the significance of cellular locomotion for leukemic infiltration was investigated using l 5222 rat leukemia cells. previous cinemicrographic studies have shown that these cells are able to locomote only after formation of a uropod-like posterior extension. this characteristic locomotive configuration of l 5222 cells is easily recognizable in scanning electron micrographs and appropriate sections. leukemia cells were inoculated on slices of chick embryo mesonephros incubated for 24h; at this tim ... | 1977 | 403674 |
| neurite induction in mature cortical neurones in feline gm1-ganglioside storage disease. | | 1977 | 404568 |
| effects of 19-hydroxy-prostaglandins on oviductal and uterine motility. | the effects of 19-hydroxyprostaglandins (19-oh-pgs) were tested in vivo on the rabbit oviduct and uterus and on the rhesus monkey (macaca mulatta) uterus. the 19-oh-pges suppressed spontaneous oviductal and uterine activity in the rabbit. the qualitative effect on the rabbit oviduct of 19-oh-pges was similar to that of pge2. however, the typical response of the rabbit uterus to pge2 was an increase in muscle activity. with regard to the rabbit oviduct, 19(r)-oh-pge2 was as potent as pge2, but 19 ... | 1977 | 404673 |
| [study of intestinal infections in experiments on monkeys]. | | 1977 | 410189 |
| oral immunization of monkeys with polyvalent dysentery vaccine. | macaca mulatta monkeys were immunized orally with polyvalent boivin extract of shigella flexneri 2a, 3a, 4a, 4b, 6 and shigella sonnei. the total immumizing dose for each component was equivalent to 1.2 x 10(12) cells. after challenge with 7.5 x 10(10) cells of a virulent s. flexneri 2a strain, out of 20 immunized animals 2 developed dysentery and 4 showed mild dyspepsia; all 6 control animals became ill with dysentery. vaccination failed to influence the incidence, duration or the intermittent ... | 1977 | 412396 |
| [safety and immunologic effectiveness of polyantigen from shigellae for oral immunization of monkeys]. | clinical, morphological, and immunological study was carried out in monkeys given shigellae antigen in tablets orally. each tablet contained 0.5 mg of the antigens obtained by boiven's method from sh. flexneri 2a, 3, 4a, 4b, 6 and sh. sonnei. daily administration of the preparation for 4 days and then 4 times at the interval of 5 days proved to be harmless for monkeys. a marked immunomorphological reaction in the form of hyperplasia of the lymphoid elements of the wall of the large intestine and ... | 1977 | 413291 |
| theileria parva piroplasmosis in mice, and its attempted transmission with rhipicephalus appendiculatus ticks. | theileria parva piroplasm infection of mouse erythrocytes was detected, following intraperitoneal inoculation of mice with irradiated cultures of t. parva-infected bovine lymphoid cells. infection could not be transmitted to cattle using rhipicephalus appendiculatus ticks. | 1977 | 414389 |
| the use of tetracyclines on the chemotherapy of experimental east coast fever (theileria parva infection of cattle). | in a series of experiments, groups of cattle, undergoing patent east coast fever (ecf) reactions induced by the inoculation of tick-derived stabilates of theileria parva infective particles, were treated by parenteral administration of 2 tetracyclines. ten cattle were treated with n-pyrrolidinomethyl tetracycline at 15 mg/kg for 5 days, starting on the first day macroschizonts were detected in lymph node biopsy smears. nine of these treated cattle survived ecf reactions induced by an inoculum wh ... | 1977 | 414390 |
| antilymphocyte antibodies in systemic lupus erythematosus patients and their relatives: reactivity with nonhuman lymphocytes. | | 1978 | 414873 |
| [coryneform bacterias of the bovine udder]. | | 1978 | 414906 |
| immunochemical and biochemical studies demonstrating the identity of a bovine spinal cord protein (scp) and a basic protein of bovine peripheral myelin (bf). | | 1978 | 415121 |
| [aggravation of experimental dysentery in mice and acceleration of the process of multiplication of pathogenic and conditionally pathogenic bacteria under the effect of yeast rna]. | simultaneous infection of mice with sh. flexneri subtype 2a, culture, with various doses of rna sodium salt (narna) or administration of the preparation 3 hours prior to or 6, 12, and 18 hours after the infection was accompanied by aggravation of the experimental infection in mice. this was expressed in a greater number of animals which contracted the disease and died, and in increased blood and peritoneal exudate microbiol density. the same processes were noted in mice infected with equal doses ... | 1978 | 415460 |
| nature of collagens synthesized by monkey periodontal-ligament fibroblasts in vitro. | 1. first subcultures of fibroblast-like cells from adult monkey periodontal ligament were incubated in the presence of 14c-labelled amino acids and produced significant amounts of type-i and type-iii collagens. 2. the proportion of type-iii collagen produced was calculated on the basis of the recovery of procollagens from deae-cellulose chromatography to be approx. 20%, and at least 10% when analysed as collagens on cm-cellulose chromatography. 3. sodium dodecyl sulphate/polyacrylamide-gel elect ... | 1978 | 415740 |
| presence of common idiotypes on antibodies induced by glutamic acid-lysine-containing terpolymers in responder and nonresponder mice with the ig-1b heavy chain allotype. | a b10.a (5r) responder mouse to the random linear terpolymer, poly--(glu, lys, phe), glphi, can produce immunoglobulins which bind poly-l (glu, lys), gl, that share idiotypic determinants with gl-binding antibodies produced by other members of the same strain. expression of these common idiotypic determinants, termed bgl, is independent of the h-2 halotype and closely linked to the ig-lb heavy chain allotype. moreover, nonresponder mice with the ig-lb heavy chain allotype, when immunized with gl ... | 1977 | 415884 |
| specific antiserum to the main intrinsic polypeptide of chick lens fiber cell plasma membranes. | | 1978 | 415893 |
| proposals for quality control methods of bacterial vaccines for immunostimulation. iii. effect of bcg and c. parvum on in vivo listeria clearance and tumor growth. | two quality control methods for bcg and c. parvum are described. first, in vivo macrophage dependent-spleen clearance of listeria monocytogenes in inbred b10lp mice. bcg and c. parvum were administered intravenously prior to listeria inoculation (a prophylactic model). conditions for enhanced listeria clearance including dose, route and time interval were described for each vaccine. next, a tumor model was developed: i.e. a fibrosarcoma, chemically induced by 20-methylcholanthrene in inbred balb ... | 1977 | 415924 |
| pharmacokinetics of intracarotid artery 14c-bcnu in the squirrel monkey. | a comparison of intravenous to intracarotid artery (ica) administration of 14c-bcnu (1,3-bis(2-chloroethyl)-1-nitrosourea) was made in squirrel monkeys. radioactivity was measured as soluble drug products and as rna-, dna-, and protein-bound radioactivity. the ica administration of bcnu achieved 190% to 280% higher brain nucleic acid-bound drug levels than use of the intravenous route in the infused hemisphere and 130% to 280% higher levels than in the noninfused hemisphere. in addition, some br ... | 1978 | 416182 |
| relationship between blood flow velocity in the choroid and intraocular pressure in rabbits. | by using thermistors for calorimetry to monitor blood flow velocity in the choroid of the anaesthetized rabbit, it was found that an elevation of intraocular pressure reduced the choroidal blood flow. the relationship between the ratio of perfusion pressure to intraocular tension (x) and the reciprocal value of the percentage of blood flow velocity (l/y) showed a curve convex towards the pressure axis. on a log-lin scale the graph was linear. a significant linear correlation with a coefficient o ... | 1979 | 419976 |
| skeletal changes in the condylar cartilage of the neonate mouse mandible. | histological and histochemical qualitative and quantitative determinations are provided concerning the skeletal changes taking place in the growth center of the mandibular condyle in the neonatal icr mouse. this study followed the changes in both the major matrical components (collagen, acidic glycosaminoglycans and glycolipids) as well as in the various cartilage cells throughout the maturational period of the neonatal condyle. it was found that the transformation of neonatal condylar cartilage ... | 1979 | 420892 |
| projection from the vestibular nuclei to the inferior olive in the cat: an autoradiographic and horseradish peroxidase study. | injections of horseradish peroxidase (hrp) in the inferior olive of 13 cats resulted in the labeling of neurons in the medial (mvn) and descending vestibular nuclei (dvn) as well as in subgroups g, p.h., s.v., x and z. the contribution of groups p.h. and z. could not be definitively established. injections of triated leucine in the vestibular nuclei and adjacent reticular formation in 4 cats indicated that the previously identified vestibular nuclei and subgroups project bilaterally to the dorso ... | 1979 | 421137 |
| the canine eye: the vessels of aqueous drainage. | lumenal castings of canine vessels of aqueous drainage, prepared by microvascular injection of room-temperature vulcanizing silicone or batson's methacrylate corrosion compound no. 17, were viewed with a stereo dissecting microscope and by scanning electron microscopy. the pathways for aqueous drainage in the dog appear to extend radially from the interstices of the filtering meshwork, through the deep intrascleral venous plexus, to the midscleral venous circle of hovius, which also serves choro ... | 1979 | 422328 |
| high pressure liquid chromatographic determination of nitrofurazone in milk. | a rapid high pressure liquid chromatographic (hplc) screening method for the quantitative determination of nitrofurazone in milk has been developed. the drug is extracted with ethyl acetate from a 2.0 ml milk serum sample, the organic layer is evaporated to dryness, and the residue is dissolved in the mobile phase and injected into the liquid chromatogarph. a reverse phase mubondapak c18 column is used with monitoring at 365 nm. the detection limit is 5 ppb and recoveries are 57--67%. mass spect ... | 1979 | 422501 |
| comparison of the membrane composition of spiroplasma citri and the corn stunt spiroplasma. | components of membranes isolated from spiroplasma citri and corn stunt spiroplasma grown at 28 degrees c were analyzed. on a protein basis, lipid phosphorus was lower and cholesterol was higher in s. citri. only minor differences between the two species were found in fatty acid composition, reduced nicotinamide adenine dinucleotide diaphorase, and adenosine triphosphatase. | 1979 | 422510 |
| incidence and pathological features of spontaneous tumors in athymic nude mice. | systematic observation of 1141 nude mice (swiss background [corrected] strain) that received human tumor transplants revealed 24 spontaneous tumors, 18 of lymphoreticular origin and 6 pulmonary adenomas. spontaneous tumors were seen at an average age of 9.1 months, and 22 of the tumors were seen only in that fraction of our group (324 mice) surviving for 5 months or more (22 of 324 x 100 = 6.8%). transplantation of these tumors to other nude mice was successful in three of five cases. mice trans ... | 1979 | 427772 |
| multi-element analysis of the rat hippocampus by proton induced x-ray emission spectroscopy (phosphorus, sulphur, chlorine, potassium, calcium, iron, zinc, copper, lead, bromine, and rubidium). | a technique for multi-element analysis of brain tissue by proton induced x-ray emission spectroscopy (pixe) is described and data from analysis of fixed and unfixed samples from rat hippocampus, neocortex, amygdala, and spinal cord is presented and commented on. the atoms present in the tissue are bombarded with protons which causes the ejection of electrons from the inner shells. when the "holes" are refilled with electrons from outer shells, x-ray quanta characteristic for each element are emi ... | 1979 | 429203 |