| epigenetic activation of antibacterial property of an endophytic streptomyces coelicolor strain azra 37 and identification of the induced protein using maldi tof ms/ms. | the endophytic streptomyces coelicolor strain azra 37 was isolated from the surface sterilized root of azadirachta indica a. juss., commonly known as neem plant in india. since only a few reports are available regarding epigenetic modulations of microbial entities, s. coelicolor was treated with different concentrations of 5-azacytidine for this purpose and evaluated for its antibacterial potential against five human pathogenic bacteria (aeromonas hydrophila ims/gn11, enterococcus faecalis ims/g ... | 2016 | 26844762 |
| evaluating the antimicrobial activity of commercially available herbal toothpastes on microorganisms associated with diabetes mellitus. | the present study was conducted to evaluate the effcacy of commercially available herbal toothpastes against the different periodontopathogens. | 2013 | 24685799 |
| azadirachtin production by hairy root cultivation of azadirachta indica in a modified stirred tank reactor. | present investigation involves hairy root cultivation of azadirachta indica in a modified stirred tank reactor under optimized culture conditions for maximum volumetric productivity of azadirachtin. the selected hairy root line (az-35) was induced via agrobacterium rhizogenes lba 920-mediated transformation of a. indica leaf explants (coimbatore variety, india). liquid culture of the hairy roots was developed in a modified murashige and skoog medium (mm2). to further enhance the productivity of ... | 2012 | 22580745 |
| rapid, bioassay-guided process for the detection and identification of antibacterial neem oil compounds. | bioassay guidance was used along the whole process including method development, isolation and identification of antibacterial neem (azadirachta indica) oil compounds. the biomonitoring was performed by direct bioautography (db), a combination of thin-layer chromatography (tlc) and antimicrobial detection. db of neem oil showed one antibacterial zone that was not uv-active; therefore, the tlc separation was improved under db control. the chromatographic zone that exhibited activity against bacil ... | 2016 | 26951543 |
| effect of elicitors and precursors on azadirachtin production in hairy root culture of azadirachta indica. | the present study involved strategies for enhancement in in vitro azadirachtin (commercially used biopesticide) production by hairy root cultivation of azadirachta indica. improvement in the azadirachtin production via triggering its biosynthetic pathway in plant cells was carried out by the exogenous addition of precursors and elicitors in the growth medium. among the different abiotic stress inducers (ag(+), hg(+2), co(+2), cu(+2)) and signal molecules (methyl jasmonate and salicylic acid) tes ... | 2014 | 24357500 |
| screening the antifungal activity of essential oils against decay fungi from palmyrah leaf handicrafts. | the whitish tender leaves of palmyrah are used for making handicrafts. the problem with these articles is discolouration with time and become more brittle due to fungal attack. this could be prevented by some protective coating. instead of expensive and harmful chemicals we decided to test natural plant essential oils to control fungal attack. palmyrah leaf article decay fungi were isolated from two different sites of jaffna peninsula. in this investigation antifungal activity of different plant ... | 2014 | 25287894 |
| antifungal activity of different neem leaf extracts and the nimonol against some important human pathogens. | this study was conducted to evaluate the effect of aqueous, ethanolic and ethyl acetate extracts from neem leaves on growth of some human pathogens (aspergillus flavus, aspergillus fumigatus, aspergillus niger, aspergillus terreus, candida albicans and microsporum gypseum) in vitro. different concentrations (5, 10, 15 and 20%) prepared from these extracts inhibited the growth of the test pathogens and the effect gradually increased with concentration. the 20% ethyl acetate extract gave the stron ... | 2011 | 24031718 |
| biosynthesis of anti-proliferative gold nanoparticles using endophytic fusarium oxysporum strain isolated from neem (a. indica) leaves. | here we report a simple, rapid, environment friendly approach for the synthesis of gold nanoparticles using neem (azadirachta indica a. juss.) fungal endophyte, which based upon morphological and cultural characteristics was eventually identified as fusarium oxysporum. the aqueous precursor (haucl4) solution when reacted with endophytic fungus resulted in the biosynthesis of abundant amounts of well dispersed gold nanoparticles of 10-40 nm with an average size of 22nm. these biosynthesized gold ... | 2016 | 26876519 |
| enhanced production of pectinase by aspergillus terreus ncft 4269.10 using banana peels as substrate. | aspergillus terreus ncft4269.10 was implemented in solid-state (ssf) and liquid static surface fermentation (lssf) for biosynthesis of pectinase. amongst various substrates, like, mustard oil cake, neem oil cake, groundnut oil cake, black gram peels, green gram peels, chickling vetch peels/grass pea peels wheat bran, pearl millet residues, finger millet waste, broken rice, banana peels (bp), apple pomace (ap) and orange peels, banana peel (musa paradisiaca l.; family: musaceae) was most suitable ... | 2016 | 28330106 |
| botanical and biological pesticides elicit a similar induced systemic response in tomato (solanum lycopersicum) secondary metabolism. | natural pesticides have attracted substantial interest due to the increase in organic agriculture and enhanced attention to environmental pollution. plant growth promoting bacteria (pgpb) are applied for both disease control and growth enhancement; pgpbs are known to elicit induced systemic response (isr) in plants. however, less is known about the effect of botanical pesticides, such as the azadirachtin-containing neem extracts, on plant metabolism. this study aimed to investigate the effects o ... | 2016 | 27251587 |
| bark extract mediated green synthesis of silver nanoparticles: evaluation of antimicrobial activity and antiproliferative response against osteosarcoma. | in the current investigation we report the biosynthesis potentials of bark extracts of ficus benghalensis and azadirachta indica for production of silver nanoparticle without use of any external reducing or capping agent. the appearance of dark brown color indicated the complete nanoparticle synthesis which was further validated by absorbance peak by uv-vis spectroscopy. the morphology of the synthesized particles was characterized by field emission- scanning electron microscopy (fe-sem) and ato ... | 2016 | 26478285 |
| effects of carriers, emulsifiers, and biopesticides for direct silk treatments on caterpillar feeding damage and ear development in sweet corn. | in the northeastern united states, control of lepidopteran pests of sweet corn, particularly corn earworm [helicoverpa zea (boddie)], is difficult using organic methods. the direct application of corn oil and bacillus thuringiensis (bt) to corn silk has been shown to reduce ear damage from corn earworm in past studies; these studies sought to optimize this method by evaluating additional carrier and biopesticide mixtures that comply with the united states federal insecticide, fungicide, and rode ... | 2017 | 28073976 |
| a novel cost-effective medium for the production of bacillus thuringiensis subsp. israelensis for mosquito control. | bacillus thuringiensis subsp. israelensis (bti) has been used for mosquito-control programmes the world-wide. indeed, the large-scale production of bti for mosquito control is very expensive due to the high cost of its culture. in the present study, we attempted to widen the scope in developing cost-effective culture medium for bti production, based on the raw materials available on the biosphere, including coconut cake powder, ccp (cocos nucifera), neem cake powder, ncp (azadirachta indica) and ... | 2012 | 22543607 |
| management of chinese rose beetle (adoretus sinicus) adults feeding on cacao (theobroma cacao) using insecticides. | the chinese rose beetle (adoretus sinicus burmeister (coleoptera: scarabaeidae)) is an introduced, widely-established pest in hawai'i. the adult beetles feed on the leaves of cacao (theobroma cacao l.), which can lead to defoliation and even death of young trees. we evaluated the impact of five commercially available products with different active ingredients (imidacloprid, azadirachtin, beauveria bassiana (bals.-criv.) vuill., kaolin clay, and pyrethrin) and the presence or absence of weed mat ... | 2016 | 27348004 |
| laboratory and field efficacy of entomopathogenic fungi for the management of the sweetpotato weevil, cylas formicarius (coleoptera: brentidae). | the sweetpotato weevil, cylas formicarius (f.) (coleoptera: brentidae), is one of the most important pests of sweet potatoes in the world. with free trade between the united states and the u.s.-controlled mariana islands, c. formicarius has spread along with this commodity. because of the cryptic nature of the larvae and nocturnal activity of the adults, and the cancellation of long-residual pesticides, this pest has become increasingly difficult to control. therefore, the present study sought t ... | 2014 | 25111763 |
| sustainable management tactics for control of phyllotreta cruciferae (coleoptera: chrysomelidae) on canola in montana. | the crucifer flea beetle, phyllotreta cruciferae (goeze) (coleoptera: chrysomelidae), has recently emerged as a serious pest of canola (brassica napus l.) in montana. the adult beetles feed on canola leaves, causing many small holes that stunt growth and reduce yield. in 2013, damage to canola seedlings was high (approximately 80%) in many parts of montana, evidence that when flea beetles emerge in large numbers, they can quickly destroy a young canola crop. in the current study, the effectivene ... | 2014 | 24772547 |
| insecticidal effects of deltamethrin in laboratory and field populations of culicoides species: how effective are host-contact reduction methods in india? | bluetongue virus (btv) is transmitted by culicoides biting midges and causes bluetongue (bt), a clinical disease observed primarily in sheep. bt has a detrimental effect on subsistence farmers in india, where hyperendemic outbreaks impact on smallholdings in the southern states of the country. in this study, we establish a reliable method for testing the toxic effects of deltamethrin on culicoides and then compare deltamethrin with traditional control methods used by farmers in india. | 2017 | 28143560 |
| identification of differentially expressed genes in monochamus alternatus digested with azadirachtin. | the pine sawyer beetle monochamus alternatus hope, a major forest insect pest, is the primary vector of the destructive forest pest pine wood nematode, bursaphelenchus xylophilus. azadirachtin, an active compound of neem, is biologically interesting because it represents a group of important, successful botanical pesticides. we provide insight into the molecular effects of azadirachtin on m. alternatus at the transcriptional level to provide clues about possible molecular-level targets and to es ... | 2016 | 27629396 |
| antimicrobial activity of essential oils and five terpenoid compounds against campylobacter jejuni in pure and mixed culture experiments. | the aim of this study was to examine the antimicrobial potential of three essential oils (eos: tea tree oil, lemon myrtle oil and leptospermum oil), five terpenoid compounds (α-bisabolol, α-terpinene, cineole, nerolidol and terpinen-4-ol) and polyphenol against two strains of campylobacter jejuni (acm 3393 and the poultry isolate c338), campylobacter coli and other gram negative and gram positive bacteria. different formulations of neem oil (azadirachta indica) with these compounds were also tes ... | 2013 | 24041998 |
| natural control of bacteria affecting meat quality by a neem (azadirachta indica a. juss) cake extract. | the antibacterial activity of an ethylacetate neem cake extract (nce) against bacteria that affect meat quality, namely campylobacter jejuni, carnobacterium spp., lactobacillus curvatus, lactobacillus sakei and leuconostoc sp., is reported. the antibacterial activity was detected using standardised disc diffusion and macrodilution methods. the bacterial growth inhibition zone ranged from 11.33 ± 0.58 to 22.67 ± 0.58 mm (100 μl nce). there is significant difference between the growth inhibition z ... | 2015 | 25272067 |
| antibacterial efficacy of azadirachta indica, mimusops elengi and 2% chx on multispecies dentinal biofilm. | to check the antimicrobial activity of azadirachta indica (neem), mimusops elengi (bakul), and chlorhexidine gluconate (chx) on multispecies biofilm of common endodontic pathogens such as streptococcus mutans, enterococcus faecalis, staphylococcus aureus and candida albicans. | 2017 | 26752840 |
| comparison of antimicrobial efficacy of triclosan- containing, herbal and homeopathy toothpastes- an invitro study. | use of antimicrobial agents is one of the important strategies to prevent oral diseases. these agents vary in their abilities to deliver preventive and therapeutic benefits. | 2015 | 26557516 |
| silver nanoparticles embedded mesoporous sio₂ nanosphere: an effective anticandidal agent against candida albicans 077. | candida albicans is a diploid fungus that causes common infections such as denture stomatitis, thrush, urinary tract infections, etc. immunocompromised patients can become severely infected by this fungus. development of an effective anticandidal agent against this pathogenic fungus, therefore, will be very useful for practical application. in this work, ag-embedded mesoporous silica nanoparticles (msio2@agnps) have successfully been synthesized and their anticandidal activities against c. albic ... | 2015 | 26119911 |
| dentinal tubule disinfection with propolis & two extracts of azadirachta indica against candida albicans biofilm formed on tooth substrate. | this study evaluates the disinfection of dentinal tubules using propolis, azadirachta indica (alcoholic and aqueous extracts), 2% chlorhexidine gel and calcium hydroxide against candida albicans biofilm formed on tooth substrate. | 2015 | 26962368 |
| guaiane sesquiterpenes and isopimarane diterpenes from an endophytic fungus xylaria sp. | nine oxygenated guaiane-type sesquiterpenes and three isopimarane diterpenes were isolated from the culture broth of an endophytic fungus, xylaria sp. ym 311647, obtained from azadirachta indica. the structures of these compounds were elucidated by interpretation of spectroscopic data. the absolute configurations of two of these were confirmed by x-ray crystallographic analysis. all of the compounds were tested for their antifungal activities against five pathogenic fungal cells. the results sho ... | 2014 | 24890390 |
| in vitro evaluation of antimicrobial effect of miswak against common oral pathogens. | miswak is a natural tooth cleaning tool which is being used in many parts of the world since ancient times. it is known to be useful in prevention of dental caries. but still it is not used as frequently as other oral hygiene tools. this research was designed to scientifically establish antimicrobial effect of miswak in vitro against common oral pathogens. | 2014 | 24772151 |
| cyclonerol derivatives from trichoderma longibrachiatum ym311505. | a new sesquiterpene, 10,11-dihydrocyclonerotriol (1), together with two known compounds, catenioblin c (2) and sohirnone a (3), were isolated from trichoderma longibrachiatum ym311505, an endophytic fungus of azadirachta indica. their structures were characterized and identified by spectral analysis. compounds 1-3 exhibited antifungal activities against pyricularia oryzae and candida albicans. | 2014 | 24689203 |
| comparison of antimicrobial efficacy of propolis, morinda citrifolia, azadirachta indica (neem) and 5% sodium hypochlorite on candida albicans biofilm formed on tooth substrate: an in-vitro study. | endodontic infections are polymicrobial in nature. candida albicans is the most common fungus isolated from failed endodontic cases. the constant increase in antibiotic resistant strains and side-effects caused by synthetic drugs has prompted researchers to look for herbal alternatives such as propolis, morinda citrifolia and azadirachta indica (neem) etc., since, the gold standard for irrigation, i.e., sodium hypochlorite has many disadvantages. | 2013 | 24347888 |
| in vitro evaluation of five different herbal extracts as an antimicrobial endodontic irrigant using real time quantitative polymerase chain reaction. | sodium hypochlorite is the most commonly used irrigant but it has disadvantage like high cytotoxicity. so there is a need to find an alternative to 5.25% sodium hypochlorite against microorganism enterococcus faecalis and candida albicans. literature has shown that these 5 extracts namely terminalia chebula, myristica frangrans, aloe barbadensis, curcuma longa and azadaricta indica has good properties which can be used as a potential endodontic irrigant. | 2013 | 23716972 |
| antimicrobial efficacy of endodontic irrigants from azadirachta indica: an in vitro study. | this study analyzed the antimicrobial effect of five irrigants formulated from different parts of the tree azadirachta indica (neem) and compared with 2.5% sodium hypochlorite and 0.2% chlorhexidine gluconate through an agar diffusion test. | 2013 | 23638768 |
| neem (azadirachtaindica a. juss) oil: a natural preservative to control meat spoilage. | plant-derived extracts (pdes) are a source of biologically-active substances having antimicrobial properties. the aim of this study was to evaluate the potential of neem oil (no) as a preservative of fresh retail meat. the antibacterial activity of no against carnobacterium maltaromaticum, brochothrix thermosphacta, escherichia coli, pseudomonas fluorescens, lactobacillus curvatus and l. sakei was assessed in a broth model system. the bacterial growth inhibition zone (mm) ranged from 18.83 ± 1.1 ... | 2015 | 28231186 |
| organic neem compounds inhibit soft-rot fungal growth and improve the strength of anthracite bricks bound with collagen and lignin for use in iron foundry cupolas. | to examine organic neem compounds for their effective growth inhibition of saprotrophic soft-rot fungi on anthracite bricks bound with collagen and lignin for use in iron foundry cupolas as an alternative fuel source. | 2015 | 25857444 |
| biotransformation of oral contraceptive ethynodiol diacetate with microbial and plant cell cultures. | | 2012 | 23021311 |
| in silico evaluation of inhibitory potential of triterpenoids from azadirachta indica against therapeutic target of dengue virus, ns2b-ns3 protease. | ns2b-ns3 protease (ns2b-ns3 pro ) of dengue virus (denv) is the prime therapeutic target for the development of anti-dengue drug to combat the denv infection, which is currently an increasing health problem in many countries. in the area of antiviral drug discovery, numerous reports on the antiviral activity of various medicinal plants against dengue viruses have been published. neem plant (azadirachta indica) is one among those medicinal plants which is reported to show potential antiviral acti ... | 2017 | 27353586 |
| ethanolic extract of azadirachta indica (a. juss.) causing apoptosis by ros upregulation in dirofilaria immitis microfilaria. | dirofilaria immitis is the causative agent of cardiopulmonary dirofilariasis in the canine family. the aim of the study was to evaluate the efficacy of the ethanolic extract of azadirachta indica leaves (eea) against the microfilaria (mf) of d. immitis in vitro. eea was evaluated for different compound classes through hptlc. relative motility, mortality and morphological alterations were observed in the mf after exposure to eea. the effect of eea on redox status in the treated mf was evaluated b ... | 2014 | 25092478 |
| osmoregulatory and tegumental ultrastructural damages to protoscoleces of hydatid cysts echinococcus granulosus induced by fungal endophytes. | characteristic ultrastructural changes were observed when protoscoleces of hydatid cysts echinococcus granulosus was treated with extract of endophytic fungi eupenicillium and chaetomium sp. isolated from azadirachta indica and piper longum plants respectively. a sharp decrease in viability of protoscoleces was observed after 6 h of incubation with fungal extracts. the ultrastructural changes included rosteller disorganization, loss of hooks and shedding of the microtriches of scolex region. the ... | 2014 | 25320499 |
| anticestodal activity of endophytic pestalotiopsis sp. on protoscoleces of hydatid cyst echinococcus granulosus. | surgery is still the main treatment in hydatidosis caused by echinococcus, which is a global health problem in human and animals. so, there is need for some natural protoscolicidal agents for instillation to prevent their reoccurrence at therapeutic doses. in this present investigation, anticestodal activity of one of the endophytic fungi pestalotiopsis sp. from neem plant was observed on protoscoleces of hydatid cysts of echinococcus granulosus. viability of protoscoleces was confirmed by 0.1% ... | 2013 | 24063003 |
| cytotoxic and melanogenesis-inhibitory activities of limonoids from the leaves of azadirachta indica (neem). | seventeen limonoids (tetranortriterpenoids), 1-17, including three new compounds, i.e., 17-defurano-17-(2,5-dihydro-2-oxofuran-3-yl)-28-deoxonimbolide (14), 17-defurano-17-(2ξ-2,5-dihydro-2-hydroxy-5-oxofuran-3-yl)-28-deoxonimbolide (15), and 17-defurano-17-(5ξ-2,5-dihydro-5-hydroxy-2-oxofuran-3-yl)-2',3'-dehydrosalannol (17), were isolated from an etoh extract of the leaf of neem (azadirachta indica). the structures of the new compounds were elucidated on the basis of extensive spectroscopic an ... | 2014 | 24634075 |
| report: in vivo anticoccidial effects of azadirachta indica and carica papaya l. with salinomycin drug as a dietary feed supplement in broiler chicks. | a total of thirty suspected broiler chicks were screened for coccidiosis, of them 25 chicks were found to be infected with coccidiosis viz. eimeria tenella (15) eimeria maxima (5) eimeria necatrix (6) and eimeria mitis (4). the anticoccidial efficacy of azadirachta indica and carica papaya with salinomycin as a dietary feed supplement on the representative e. tenella (25 x 10³ oocyst) infection challenged in broiler chicks was studied in six groups for the period of six weeks. a. indica and c. p ... | 2015 | 26142532 |
| protective effect of azadirachta indica extract against eimeria papillata-induced coccidiosis. | coccidiosis in poultry is caused by protozoan parasites of the genus eimeria, which is responsible for worldwide economic losses. the methanolic extract of azadirachta indica (neem) leaves was used in vivo for its pharmacological, antioxidant, and anticoccidial properties. four groups of mice were investigated. the first group was inoculated only with sterile saline and served as the control group. the second group was treated by oral gavage with neem extract (500 mg/kg) daily for 4 days. the th ... | 2013 | 22972359 |
| antibacterial efficacy of neem (azadirachta indica) extract against enterococcus faecalis: an in vitro study. | debridement and disinfection of the root canal is a crucial step in the success of endodontic treatment. several antimicrobial agents alone or in combination are used to achieve this. the objective of this in vitro study was to assess the antimicrobial efficacy of neem (azadirachta indica) extract against enterococcus faecalis. | 2016 | 27794147 |
| evaluation of the antibacterial efficacy of azadirachta indica, commiphora myrrha, glycyrrhiza glabra against enterococcus faecalis using real time pcr. | to compare the antibacterial efficacy of azadirachta indica (neem), commiphora myrrha (myrrh), glycyrrhiza glabra (liquorice) with 2% chlorhexidine (chx) against e. faecalis by using real time pcr. | 2016 | 27386000 |
| comparative evaluation of antimicrobial effect of herbal root canal irrigants (morinda citrifolia, azadirachta indica, aloe vera) with sodium hypochlorite: an in vitro study. | successful root canal treatment involves the complete elimination of microorganism from the root canal and the three-dimensional obturation of the canal space. enterococcus faecalis is the most commonly found bacteria in failed root canal. chemical irrigation of canals along with biomechanical preparation helps in the elimination of microorganisms. the present study was aimed to evaluate the antimicrobial effect of herbal root canal irrigants (morinda citrifolia, azadirachta indica extract, aloe ... | 2017 | 27382533 |
| antimicrobial activity of herbal medicines (tulsi extract, neem extract) and chlorhexidine against enterococcus faecalis in endodontics: an in vitro study. | successful endodontic treatment depends on effective disinfection and complete sealing of root canal. various medicaments are advised for disinfecting root canal, such as herbal and non-herbal medicaments. this study was done to assess the antimicrobial activity of herbal medicines (neem extract, tulsi extract) and chlorhexidine against enterococcus faecalis in endodontics. | 2015 | 26942123 |
| an in vitro evaluation of antimicrobial activity of five herbal extracts and comparison of their activity with 2.5% sodium hypochlorite against enterococcus faecalis. | sodium hypochlorite is the most widely used irrigant in endodontic practice, but it has various disadvantages. literature has shown that herbal products such as propolis, azadirachta indica (ai), triphala, curcuma longa, and morinda citrifolia (mc) possess good antimicrobial properties and thus can be used as potential endodontic irrigants. | 2015 | 26672425 |
| biofilm forming capacity of enterococcus faecalis on gutta-percha points treated with four disinfectants using confocal scanning laser microscope: an in vitro study. | the aim of this study was to evaluate and compare the in vitro biofilm forming capacity of enterococcus faecalis on gutta-percha points disinfected with four disinfectants. | 2017 | 26288622 |
| the antimicrobial activity of azadirachta indica, mimusops elengi, tinospora cardifolia, ocimum sanctum and 2% chlorhexidine gluconate on common endodontic pathogens: an in vitro study. | to check the antimicrobial activity of azadirachta indica (neem), ocimum sanctum (tulsi), mimusops elelngi (bakul), tinospora cardifolia (giloy) and chlorhexidine gluconate (chx) on common endodontic pathogens like streptococcus mutans, enterococcus faecalis and staphylococcus aureus. | 2014 | 24966766 |
| comparison of the antibacterial efficiency of neem leaf extracts, grape seed extracts and 3% sodium hypochlorite against e. feacalis - an in vitro study. | e. faecalis is the predominant micro-organism recovered from root canal of the teeth where previous endodontic treatment has failed. thorough debridement and complete elimination of micro-organisms are objectives of an effective endodontic treatment. for many years, intracanal irrigants have been used as an adjunct to enhance antimicrobial effect of cleaning and shaping in endodontics. the constant increase in antibiotic-resistant strains and side-effects of synthetic drugs has promoted research ... | 2013 | 24453446 |
| influence of various herbal irrigants as a final rinse on the adherence of enterococcus faecalis by fluorescence confocal laser scanning microscope. | the aim of this study was to assess the antibacterial efficacy of three different herbal irrigants against enterococcus faecalis. | 2013 | 23956540 |
| the in vitro antiviral property of azadirachta indica polysaccharides for poliovirus. | azadirachta indica a. juss, popularly known as neem, has been extensively used in ayurvedic medicine by indian population for over 2000 years. it is used traditionally for the healing of various diseases. natural products and their derivatives provide an excellent source for new anti-viral drugs. | 2012 | 22855945 |
| immuno-pathological studies on broiler chicken experimentally infected with escherichia coli and supplemented with neem (azadirachta indica) leaf extract. | the present study was conducted to evaluate the effects of neem leaf extract (nle) supplementation on immunological response and pathology of different lymphoid organs in experimentally escherichia coli challenged broiler chickens. | 2016 | 27536035 |
| preliminary phytochemical screening, antibacterial potential and gc-ms analysis of two medicinal plant extracts. | the presence study was aimed to catalyze the primary metabolites and their confirmation by using gc-ms analysis and antibacterial potential of leaf extract of two important medicinal plant viz., eucalyptus and azadirachta indica. the antibacterial potential of the methanol leaf extract of the studied species was tested against escherichia coli, pseudomonas aeruginosa, klebsiellap neumoniae, streptococcus pyogens, staphylococcus aureus using by agar well diffusion method. the higher zone of inhib ... | 2016 | 27166527 |
| a solvent induced crystallisation method to imbue bioactive ingredients of neem oil into the compact structure of poly (ethylene terephthalate) polyester. | neem oil, a natural antibacterial agent from neem tree (azadarichtaindica) has been used to impart antibacterial activity to polyester fabrics. solvent induced polymer modification method was used and that facilitated the easy entry of neem molecules into the compact structure of polyethylene terephthalate (pet) polyester. the polyester fabric was treated with trichloroacetic acid-methylene chloride (tcamc) solvent system at room temperature prior to treatment with neem oil. the concentration of ... | 2016 | 27127070 |
| biochemical studies in experimentally escherichia coli infected broiler chicken supplemented with neem (azadirachta indica) leaf extract. | an experimental study was conducted on 192-day-old broiler chicks for evaluating the effect of 10% neem leaf extract (nle) supplementationon biochemical parameters in chickens experimentally infected with escherichia coli o78 at 10(7) cfu/0.5 ml at 7 days of age. | 2015 | 27047040 |
| physical and antimicrobial properties of starch-pva blend films as affected by the incorporation of natural antimicrobial agents. | in this work, active films based on starch and pva (s:pva ratio of 2:1) were developed by incorporating neem (no) and oregano essential oils (oeo). first, a screening of the antifungal effectiveness of different natural extracts (echinacea, horsetail extract, liquid smoke and neem seed oil) against two fungus (p. expansum and a. niger) was carried out. the effect of no and oeo incorporation on the films' physical and antimicrobial properties was analyzed. only composite films containing oeo exhi ... | 2015 | 28231098 |
| facile green fabrication of nanostructure zno plates, bullets, flower, prismatic tip, closed pine cone: their antibacterial, antioxidant, photoluminescent and photocatalytic properties. | green synthesis of multifunctional zinc oxide nanoparticles (nps) with a variety of morphologies were achieved by low temperature solution combustion route employing neem (azadirachta indica) extract as fuel. the nanoparticles were characterized by pxrd, ftir, xps, raman and uv-visible spectroscopic studies. the morphologies were studied by sem and tem analysis. the nps were subjected for photoluminescence, photocatalytic, antibacterial and antioxidant activity studies. pxrd pattern confirmed th ... | 2016 | 26241826 |
| neem (azadirachta indica a. juss) oil to tackle enteropathogenic escherichia coli. | neem (azadirachta indica a. juss) oil (no) was assayed against forty-eight isolates of escherichia coli by standardised disc diffusion test and microdilution test. by molecular biology characterization, fourteen isolates resulted in diarrheagenic e. coli with sixteen primer pairs that specifically amplify unique sequences of virulence genes and of 16s rrna. the no showed biological activity against all isolates. the bacterial growth inhibition zone by disc diffusion method (100 µl no) ranged bet ... | 2015 | 26064900 |
| comparative analysis of biosynthesised and chemosynthesised silver nanoparticles with special reference to their antibacterial activity against pathogens. | the present study reports the synthesis of silver nanoparticles (agnps) using both biological and chemical routes to find out the best method for control of their size and activity. the fungal agent (fusarium oxysporum) and the plant (azadirachta indica) were found to be the best source for agnps synthesis. both biosynthesis and chemosynthesis were achieved by challenging filtrate with agno3 (1 mm) solution. the synthesised nanoparticles were characterised by ultraviolet-visible spectroscopy, fo ... | 2015 | 26023154 |
| synthesis and characterization of zinc oxide-neem oil-chitosan bionanocomposite for food packaging application. | nano zinc oxide at different concentrations (0.1, 0.3 and 0.5%) and neem essential oil were incorporated into the chitosan polymer by solution cast method to enhance the properties of the bionanocomposite film. the functional groups, crystalline particle size, thermal stability and morphology were determined using ftir, xrd, tga and sem, respectively. the results showed that 0.5% nano zinc oxide incorporated composite film have improved tensile strength, elongation, film thickness, film transpar ... | 2015 | 25499891 |
| in vitro bioactivity and antimicrobial tuning of bioactive glass nanoparticles added with neem (azadirachta indica) leaf powder. | silica and phosphate based bioactive glass nanoparticles (58sio2-33cao-9p2o5) with doping of neem (azadirachta indica) leaf powder and silver nanoparticles were prepared and characterised. bioactive glass nanoparticles were produced using sol-gel technique. in vitro bioactivity of the prepared samples was investigated using simulated body fluid. x-ray diffraction (xrd) pattern of prepared glass particles reveals amorphous phase and spherical morphology with a particle size of less than 50 nm. wh ... | 2014 | 25276834 |
| novel-porous-ag0 nanocomposite hydrogels via green process for advanced antibacterial applications. | silver nanoparticles (nps) antibacterial characteristics were depends on its particle stabilization, particles size and nucleation agent. in this study, we report on green process of porous silver nanocomposite hydrogels for advanced antibacterial applications. the porous poly(acrylamide) (pam) hydrogels were developed employing sucrose as porogenator. silver nps were nucleated with natural biomass neem (azadirachta indica) leaf extracts within the porous hydrogel networks. the formation of silv ... | 2014 | 24677385 |
| differently environment stable bio-silver nanoparticles: study on their optical enhancing and antibacterial properties. | generally, limited research is extended in studying stability and applicational properties of silver nanoparticles (ag nps) synthesized by adopting 'green chemistry' protocol. in this work, we report on the synthesis of stable ag nps using plant-derived materials such as leaf extract of neem (azadirachta indica) and biopolymer pectin from apple peel. in addition, the applicational properties of ag nps such as surface-enhanced raman scattering (sers) and antibacterial efficiencies were also inves ... | 2013 | 24130832 |
| antibacterial and antiviral evaluation of sulfonoquinovosyldiacylglyceride: a glycolipid isolated from azadirachta indica leaves. | assessment of antibacterial as well as antiherpes virus activity of sulfonoquinovosyldiacylglyceride (sqdg), a glycolipid, isolated from the leaves of azadirachta indica has been described. antimicrobial activity was evaluated against gram-positive, gram-negative bacteria and herpes simplex virus. sqdg showed significant inhibitory activity against salmonella typhi and two isolates of shigella dysenteriae with mic values 32 μg ml(-1) , while three isolates of salm. typhi, escherichia coli and vi ... | 2014 | 24118020 |
| omani propolis: chemical profiling, antibacterial activity and new propolis plant sources. | propolis (bee glue) is a resinous honeybee product having a long history of application in many countries as a traditional remedy for treating wounds, burns, soar throat, stomach disorders, etc. it has been proved to possess beneficial biological effects, including antimicrobial, antioxidant, anti-inflammatory, cytotoxic, antiulcer, and many others. bees gather propolis from diverse resinous plant parts and in different phytogeographic regions its chemical composition might vary significantly. i ... | 2013 | 24053750 |
| iota-carrageenan-based biodegradable ag0 nanocomposite hydrogels for the inactivation of bacteria. | in this paper, we report the synthesis and characterization of iota-carrageenan based on a novel biodegradable silver nanocomposite hydrogels. the aim of study was to investigate whether these hydrogels have the potential to be used in bacterial inactivation applications. biodegradable silver nanocomposite hydrogels were prepared by a green process using acrylamide (am) with i-carrageenan (ic). the silver nanoparticles were prepared as silver colloid by reducing agno3 with leaf extracts of azadi ... | 2013 | 23618258 |
| bioethanol production involving recombinant c. thermocellum hydrolytic hemicellulase and fermentative microbes. | the enhancement of the biomass productivity of escherichia coli cells harbouring the truncated 903 bp gene designated as glycoside hydrolase family 43 (gh43) from clostridium thermocellum showing hemicellulase activity along with its further use in simultaneous saccharification and fermentation (ssf) process is described. (phosphoric acid) h(3)po(4)-acetone treatment and ammonia fibre expansion (afex) were the pretreatment strategies employed on the leafy biomass of mango, poplar, neem and asoka ... | 2012 | 22383050 |
| tertiary combination of freeze-dried urine of indian breeds of cow with plant products against snail lymnaea acuminata. | snail lymnaea acuminata is the intermediate host of liver fluke fasciola gigantica, which cause endemic fasciolosis among cattle population of eastern uttar pradesh. control of snail population by molluscicides is one of the effective methods to control fasciolosis. in the present study molluscicidal activity of tertiary combination of freeze-dried urine of different indian breeds of cow sahiwal, geer and tharparkar with annona squamosa seed powder, ferula asafoetida root latex, azadirachta indi ... | 2012 | 24199478 |
| evaluation of antiviral activity of plant extracts against foot and mouth disease virus in vitro. | the aim of this study was to evaluate antiviral activity of chloroformic leaves extracts of three plants: azadirachta indica, moringa oleifera and morus alba against foot and mouth disease virus using mtt assay (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide). antiviral and cytotoxic activity of each extract was evaluated as cell survival percentage and results were expressed as means ± s.d. the concentrations which resulted in cell survival percentages of greater than 50% are co ... | 2016 | 27393440 |
| chemical profile and defensive function of the latex of euphorbia peplus. | plant latex is an endogenous fluid secreted from highly specialized laticifer cells and has been suggested to act as a plant defense system. the chemical profile of the latex of euphorbia peplus was investigated. a total of 13 terpenoids including two previously unknown diterpenoids, (2s*,3s*,4r*,5r*,6r*,8r*,l1r*,13s*,14s*,15r*, 16r*)-5,8,15-triacetoxy-3-benzoyloxy-11,16-dihydroxy-9-oxopepluane and (2r*,3r*, 4s*,5r*,7s*,8s*,9s*,l3s*,14s*,15r*)-2,5,8,9,14-pentaacetoxy-3-benzoyloxy-15-hydroxy-7-is ... | 2017 | 28062071 |
| biosynthesized silver nanoparticles performing as biogenic sers-nanotags for investigation of c26 colon carcinoma cells. | in this work, two classes of silver nanoparticles (agnps) were biosynthesized with the goal to assess their reliability in vitro as surface-enhanced raman scattering (sers) nanotags. mycosynthesized silver nanoparticles (magnps) and phytosynthesized silver nanoparticles (pagnps) were produced through environmentally friendly procedures by reduction of silver nitrate with fusarium oxysporum cell filtrate and azadirachta indica extract, respectively. two cell lines, namely c26 murine colon carcino ... | 2015 | 26123850 |
| anthelmintic potential of calotropis procera, azadirachta indica and punica granatum against gastrothylax indicus. | anthelmintic activity of both ethanolic and aqueous extracts of calotropis procera flowers, azadirachta indica leaves and punica granatum fruit peel in comparison with albendazole was evaluated through in vitro studies by the worm motility inhibition assay. significant anthelmintic effects (p < 0.0005) were observed on live gastrothylax indicus worm as evident from their mortality at 4 h post exposure to both ethanolic and aqueous extracts. phytochemical analysis of extracts revealed the presenc ... | 2016 | 27876922 |
| evaluation of anthelmintic activity of biologically synthesized silver nanoparticles against the gastrointestinal nematode, haemonchus contortus. | the present study focuses on the in vitro anthelmintic activity of silver nanoparticles (agnps) synthesized using the aqueous extract of azadirachta indica against haemonchus contortus. the synthesized agnps were characterized by ultraviolet-visible (uv-vis) spectrophotometry, scanning electron microscopy (sem), transmission electron microscopy (tem) and x-ray diffraction (xrd) studies. the uv-vis spectrum exhibited a sharp peak at 420 nm, which was validated by electron microscopy, indicating t ... | 2016 | 27374616 |
| sensitivity of two in vitro assays for evaluating plant activity against the infective stage of haemonchus contortus strains. | the sensitivity of larval paralysis assay (lpa) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide-formazan (mtt-formazan) assay was compared to evaluate the anthelmintic activity of plant extracts. in this study, the methanolic extract of azadirachta indica (neem) was evaluated for its activity against the infective-stage larvae (l(3)) of susceptible and resistant haemonchus contortus strains using the two aforementioned assays. in both in vitro assays, the same serial concentrat ... | 2013 | 22961237 |
| antiviral phytochemicals identification from azadirachta indica leaves against hcv ns3 protease: an in silico approach. | hepatitis c virus (hcv) is a major health problem across the world affecting the people of all age groups. it is the main cause of hepatitis and at chronic stage causes liver cirrhosis and hepatocellular carcinoma. various therapeutics are made against hcv but still there is a need to find out potential therapeutics to combat the virus. the goal of this study is to identify the phytochemicals of azadirachta indica leaves having antiviral activity against hcv ns3 protease through molecular dockin ... | 2016 | 26274064 |
| beneficial effects of a coriolus versicolor-based vaginal gel on cervical epithelization, vaginal microbiota and vaginal health: a pilot study in asymptomatic women. | to assess the effect of a 12-day treatment using a vaginal gel based on niosomes containing hyaluronic acid, ß-glucan, alpha-glucan oligosaccharide, coriolus versicolor, asian centella, azadirachta indica and aloe vera on vaginal microbiota, cervical epithelization and vaginal health. | 2017 | 28302110 |
| combining azadirachtin and paecilomyces fumosoroseus (deuteromycotina: hyphomycetes) to control bemisia argentifolii (homoptera: aleyrodidae). | both azadirachtin and paecilomyces fumosoroseus (wize) brown & smith have been used to control the whitefly bemisia argentifolii bellows & perring, but with only moderate effectiveness. azadirachtin is a botanical insecticide derived from the neem tree, and p. fumosoroseus is an entomopathogenic fungus. to test whether these two agents might be more effective for whitefly control if used together, different rates of each were combined in laboratory bioassays in factorial treatment. both tank mix ... | 2003 | 12650340 |
| herbal extracts in oral health care - a review of the current scenario and its future needs. | oral diseases are among the major public health problems and the commonest of chronic diseases that affect mankind. the application of natural products for the control of oral diseases is considered as an interesting alternative to synthetic antimicrobials due to their lower negative impact, and for the effort to overcome primary or secondary resistance to the drug during therapy. | 2017 | 26392704 |
| the cytotoxic and antileishmanial activity of extracts and fractions of leaves and fruits of azadirachta indica (a juss.). | the leishmaniases are severe parasitic diseases that occur worldwide, caused by protozoa of the genus leishmania. studies with medicinal plants can lead to a range of possibilities for treating and improving the patients' quality of life. research on azadirachta indica fractions and extracts has shown that they have excellent anti-leishmanial activity based on bioactivity-guided fractionation of ethanolic extracts of leaves and seeds and in vitro activity against promastigotes. in this research ... | 2012 | 23096354 |
| in vitro and in vivo evaluation of anti-leishmanial and immunomodulatory activity of neem leaf extract in leishmania donovani infection. | the toxicity and emergence of resistance to available chemical drugs against visceral leishmaniasis is evoking to explore herbal treatment. one such attempt with the neem is being reported here. the current study is primarily focused to evaluate the anti-leishmanial effects of neem leaf extracts. among which, ethyl acetate fraction (eaf) alone was found to exhibit leishmanicidal effect validated through cytotoxicity assay and estimated its ic₅₀ to be 52.4 µg/ml on the promastigote stage. propidi ... | 2015 | 25747203 |
| management of root-knot nematode (meloidogyne incognita) in bottle gourd using different botanicals in pots. | a pot experiment was conducted to study the efficacy of different botanicals in varying doses for management of root-knot nematode, m. incognita in bottle gourd. the results exhibited that madar (calotropis procera) and neem (azadirachta indica) leaves application proved to be more effective in improving plant growth characters and reducing root-knot index and final nematode population. among the doses tested, higher dose of 1.5 % (w/w) was more effective than lower ones. | 2015 | 26345048 |
| control of root-knot nematodes on tomato in stone wool substrate with biological nematicides. | the efficacy of four biological nematicides on root-galling, root-knot nematode (meloidogyne incognita) reproduction, and shoot weight of tomato (solanum lycopersicum) grown in stone wool substrate or in pots with sandy soil was compared to an oxamyl treatment and a non-treated control. in stone wool grown tomato, avid® (a.i. abamectin) was highly effective when applied as a drench at time of nematode inoculation. it strongly reduced root-galling and nematode reproduction, and prevented a reduct ... | 2011 | 22791920 |
| nematicidal natural products from the aerial parts of buddleja crispa. | studies on the aerial parts of buddleja crispa yielded 13 known compounds, nonyl benzoate, hexyl p-hydroxy-cinnamate, ginipin, gardiol, 1-heptacosanol, steroidal galactoside (22 r)-stigmasta-7,9 (11)-dien-22 beta-ol-3beta-o-beta-d-galactopyranoside, 3-methoxy benzoic acid, beta-sitosterol and ursolic acid. besides this two iridoid galactosides buddlejosides a, buddlejosides b and a benzofuran-type sesquiterpene buddlejone have been isolated from the etoac fraction of b. crispa. together with the ... | 2010 | 20461624 |
| nematicidal natural products from the aerial parts of rubus niveus. | studies on the aerial parts of rubus niveus yielded six known compounds, 3,5-dihydroxy benzoic acid c(7)h(6)o(4), (1), gallic acid c(7)h(6)o(5) (2), ethyl galactoside (3), oleanolic acid (4), beta-sitosterol (5) and 3-o-[beta-d-galactopyranosyl-(12)-d-glucopyranoside (6). besides this, a gallic acid derivative with methyl substitution was synthesised as tetramethyl gallate (3). together with this derivative, compounds 1, 2, the alcohol soluble, chloroform soluble and petroleum ether soluble extr ... | 2010 | 20306362 |
| pesticidal properties of parthenin (from parthenium hysterophorus) and related compounds. | eleven sesquiterpene lactone derivatives of parthenin (1), obtained from wild feverfew, parthenium hysterophorus, were prepared by chemical and photochemical transformations. the compounds tested were a pyrazoline adduct (2) of parthenin, its cyclopropyl (3) and propenyl (4) derivatives, anhydroparthenin (5), a dihydro-deoxygenated product (6), a formate (7) and its corresponding alcohol (8) and acetate (9), a rearranged product (10), lactone (11) and hemiacetal (12). all these derivatives, alon ... | 2001 | 11455638 |
| in vitro and ex vivo activity of an azadirachta indica a.juss. seed kernel extract on early sporogonic development of plasmodium in comparison with azadirachtin a, its most abundant constituent. | neemazal(®) (na) is a quantified extract from seed kernels of neem, azadirachta indica a.juss. (meliaceae), with a wide spectrum of biological properties, classically ascribed to its limonoid content. na contains several azadirachtins (a to l), azadirachtin a (azaa) being its main constituent. azaa has been shown to inhibit microgamete formation of the rodent malaria parasite plasmodium berghei, and na was found to completely inhibit the transmission of plasmodium berghei to anopheles stephensi ... | 2016 | 27912876 |
| transmission blocking effects of neem (azadirachta indica) seed kernel limonoids on plasmodium berghei early sporogonic development. | azadirachta indica, known as neem tree and traditionally called "nature's drug store" makes part of several african pharmacopeias and is widely used for the preparation of homemade remedies and commercial preparations against various illnesses, including malaria. employing a bio-guided fractionation approach, molecules obtained from a. indica ripe and green fruit kernels were tested for activity against early sporogonic stages of plasmodium berghei, the parasite stages that develop in the mosqui ... | 2016 | 27642038 |
| in vivo and in vitro effectiveness of azadirachta indica-synthesized silver nanocrystals against plasmodium berghei and plasmodium falciparum, and their potential against malaria mosquitoes. | malaria transmission is a serious emergence in urban and semiurban areas worldwide, becoming a major international public health concern. malaria is transmitted through the bites of anopheles mosquitoes. the extensive employ of synthetic pesticides leads to negative effects on human health and the environment. recently, plant-synthesized nanoparticles have been proposed as highly effective mosquitocides. in this research, we synthesized silver nanoparticles (agnp) using the azadirachta indica se ... | 2016 | 27234530 |
| evaluation of herbal antimalarial mama decoction-amodiaquine combination in murine malaria model. | co-administration of amodiaquine with mama decoction (md), an herbal antimalarial drug comprising the leaves of mangifera indica l. (anacardiaceae), alstonia boonei de wild (apocynaceae), morinda lucida benth (rubiaceae) and azadirachta indica a. juss (meliaceae) was investigated. the practice of concurrent administration of herbal medicines with orthodox drugs is currently on the increase globally. | 2016 | 27057621 |
| protective effect of aqueous crude extract of neem (azadirachta indica) leaves on plasmodium berghei-induced renal damage in mice. | malaria is a major public health problem in the world because it can cause of death in patients. malaria-associated renal injury is associated with 45% of mortality in adult patients hospitalized with severe form of the disease. therefore, new plant extracts to protect against renal injury induced by malaria infection are urgently needed. in this study, we investigated the protective effect of aqueous crude extract of azadirachta indica (neem) leaves on renal injury induced by plasmodium berghei ... | 2015 | 26379714 |
| brine shrimp cytotoxicity and antimalarial activity of plants traditionally used in treatment of malaria in msambweni district. | in kenya, most people use traditional medicine and medicinal plants to treat many diseases including malaria. to manage malaria, new knowledge and products are needed. traditional herbal medicine has constituted a good basis for antimalarial lead discovery and drug development. | 2015 | 25495507 |
| influence of formulation ratio of the plant components on the antimalarial properties of mama decoction. | mangifera indica, alstonia boonei, morinda lucida and azadirachta indica (mama) decoction, commonly prepared and used in nigeria from 1:1:1:1 ratio of mangifera indica l. (anacardiaceae), alstonia boonei de wild (apocynaceae), morinda lucida benth (rubiaceae), and azadirachta indica a. juss (meliaceae) leaves, plus four new variants of this combination were subjected to three in vivo antimalarial test models using chloroquine-sensitive plasmodium berghei berghei to determine the most active unde ... | 2014 | 24658658 |
| azadirachta indica extract-artesunic acid combination produces an increased cure rate of plasmodium berghei-infected mice. | available artemisinin-combination therapies (acts) are expensive. various traditional herbal remedies for malaria involve plants, proven scientifically to have antiplasmodial effects, e.g., azadirachta indica a. juss. (meliaceae). | 2014 | 24517279 |
| in vivo antimalarial evaluation of mama decoction on plasmodium berghei in mice. | the use of decoctions of different plant materials is common practice in antimalarial ethnomedicine in africa. scientific evaluation of such herbal combinations to verify the claims is important. the study has evaluated the antimalarial efficacy of mama decoction (md), a multicomponent herbal preparation and its individual plant components, namely leaves of morinda lucida benth [rubiaceae] (ml), azadirachta indica a. juss [meliaceae] (ai), alstonia boonei de wild [apocynaceae] (ab) and mangifera ... | 2014 | 24271081 |
| azadirachta indica ethanolic extract protects neurons from apoptosis and mitigates brain swelling in experimental cerebral malaria. | cerebral malaria is a rapidly developing encephalopathy caused by the apicomplexan parasite plasmodium falciparum. drugs currently in use are associated with poor outcome in an increasing number of cases and new drugs are urgently needed. the potential of the medicinal plant azadirachta indica (neem) for the treatment of experimental cerebral malaria was evaluated in mice. | 2013 | 23984986 |
| brine shrimp toxicity and antimalarial activity of some plants traditionally used in treatment of malaria in msambweni district of kenya. | in kenya, most people especially in rural areas use traditional medicine and medicinal plants to treat many diseases including malaria. malaria is of national concern in kenya, in view of development of resistant strains of plasmodium falciparum to drugs especially chloroquine, which had been effective and affordable. there is need for alternative and affordable therapy. many antimalarial drugs have been derived from medicinal plants and this is evident from the reported antiplasmodial activity. | 2013 | 23791809 |
| pharmacodynamic evaluation for antiplasmodial activity of holarrhena antidysentrica (kutaja) and azadirachta indica (neemb) in plasmodium berghei infected mice model. | to investigate in-vivo anti-plasmodial activity of aqueous extracts of plants selected based on the symptomology mentioned in ayurveda. | 2013 | 23768822 |
| antimalarial plant remedies from burkina faso: their potential for prophylactic use. | saye, a combination remedy prepared from cochlospermum planchonii hook.f. (cochlospermaceae), cassia alata l. (fabaceae) and phyllanthus amarus schumach. et thonn. (euphorbiaceae), n'dribala, a cochlospermum planchonii root decoction, and a fruit preparation of azadirachta indica a. juss. (meliaceae) are plant remedies of the folk medicine in burkina faso and are commonly used by traditional healers for the treatment of malaria. | 2012 | 22301449 |
| anti-plasmodial effects of azadirachta indica in experimental cerebral malaria: apoptosis of cerebellar purkinje cells of mice as a marker. | malaria is a major public health problem in the world, but treatment of malaria is becoming more difficult due to increasing drug resistance. therefore, the need for alternative drugs is acute. | 2010 | 22558559 |
| novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor. | macrophage migration inhibitory factor (mif) is responsible for proinflammatory reactions in various infectious and non-infectious diseases. we have investigated the mechanism of anti-inflammatory activity of epoxyazadiradione, a limonoid purified from neem (azadirachta indica) fruits, against mif. epoxyazadiradione inhibited the tautomerase activity of mif of both human (humif) and malaria parasites (plasmodium falciparum (pfmif) and plasmodium yoelii (pymif)) non-competitively in a reversible ... | 2012 | 22645149 |
| efficacy of 10% whole azadirachta indica (neem) chip as an adjunct to scaling and root planning in chronic periodontitis: a clinical and microbiological study. | anti-microbial therapy is essential along with conventional therapy in the management of periodontal disease. instead of systemic chemical agents, herbal products could be used as antimicrobial agents. herbal local drug delivery systems are effective alternative for systemic therapy in managing the chronic periodontal disease. in this study, 10% neem oil chip was used as a local drug delivery system to evaluate the efficacy in the periodontal disease management. | 2016 | 27054855 |