structural characterization of as-mif and hjab1 during the inhibition of cell-cycle regulation. | the biological activities of macrophage migration inhibitory factor (mif) might be mediated through a classical receptor-mediated or non-classical endocytic pathway. jab1 (c-jun activation domain-binding protein-1) promotes the degradation of the tumor suppressor, p53, and the cyclin-dependent kinase inhibitor, p27. when mif and jab1 are bound to each other in various intracellular sites, mif inhibits the positive regulatory effects of jab1 on the activity of ap-1. the intestinal parasite, anisa ... | 2017 | 28366190 |
molecular diagnosis of allergy to anisakis simplex and gymnorhynchus gigas fish parasites. | there has been an increase in the prevalence of hypersensitivity to anisakis simplex. there are fish parasites other than anisakis simplex whose allergenicity has not yet been studied. | 2017 | 28341528 |
ige, igg1 and igg4 response to specific allergens in sensitized subjects showing different clinical reactivity to anisakis simplex. | background. anisakis simplex hypersensitive subjects may be sensitized without clinical allergy, or experience acute symptoms or chronic urticaria induced by raw fish. we studied whether the 3 subgroups differ in ige, igg1 or igg4 reactivity to specific anisakis simplex allergens. methods. 28 anisakis simplex-hypersensitive adults, 11 with acute symptoms, 9 with chronic urticaria, and 8 sensitized were studied. ige, igg1 and igg4 to rani s 1, 5, 9 and 10 were sought by elisa. ige and igg4 to nan ... | 2017 | 28294584 |
determination of anti-anisakis simplex antibodies and relationship with αβ and γδ lymphocyte subpopulations in patients with crohn's disease. | the etiology of crohn's disease (cd) is still unknown although new theories are based on defects in innate immunity. we have previously shown a decrease in γδ t cells in cd patients. previous studies have shown a high prevalence of anti-a. simplex immunoglobulins in cd patients. the diminution of γδ t cells in the peripheral blood and intestinal mucosa of cd patients may create a state of immunosuppression that would facilitate a. simplex infection. | 2017 | 28168577 |
population parameters and mito-nuclear mosaicism of anisakis spp. in the adriatic sea. | recombinant genotypes of a. simplex sensu stricto (s.s.) and a. pegreffii, two species of anisakis simplex complex found in sympatric waters of the mediterranean sea, are believed to be a product of interspecific hybridisation and/or dna introgression. in contrast, such events within an allopatric area as the adriatic sea are unlikely to occur and therefore observed recombination should be assessed more closely. we have genotyped 525 anisakids collected from migratory and non-migratory fish of t ... | 2017 | 28126544 |
contracaecum osculatum and other anisakid nematodes in grey seals and cod in the baltic sea: molecular and ecological links. | populations of grey seals (halichoerus grypus), sprats (sprattus sprattus) and cod (gadus morhua) in the baltic sea are relatively stationary. the present work, applying classical and molecular helminthological techniques, documents that seals and cod also share a common parasite, the anisakid nematode contracaecum osculatum, which uses seals as the final host and fish as transport hosts. sequencing mitochondrial genes (cox1 and cox2) in adult worms from seals and third-stage larvae from livers ... | 2017 | 28124629 |
anisakidosis: a fortuitous mimicker of gastrointestinal malignancy. | a 51-year-old woman presented with epigastric pain, vomiting and diarrhoea. her sister was recently diagnosed with duodenal adenocarcinoma, manifesting similar symptoms. imaging revealed thickened gastric antrum with enlarged local lymph nodes. endoscopy illustrated 3 worms embedded in the antral wall, identified as anisakis simplex larvae. larvae removal and a 2-week albendazole regimen treated the symptoms. with globalisation of cultural culinary practices, physicians must be vigilant of anisa ... | 2016 | 27600057 |
species composition and infection dynamics of ascaridoid nematodes in barents sea capelin (mallotus villosus) reflecting trophic position of fish host. | capelin (mallotus villosus) is among the most abundant fish species in the barents sea, and represents a critical food source for many predators in the area including atlantic cod and harp seal. in norway, the fish is of economic importance since whole capelin and roe are valuable export products. despite its economic and ecological importance, the parasites of barents sea capelin are poorly known. however, the presence of parasites in the edible parts may adversely affect product quality and co ... | 2016 | 27473836 |
nonoccupational airborne-induced anaphylaxis caused by anisakis simplex. | | 2016 | 27326991 |
anisakiasis causing acute dysentery in malaysia. | human anisakiasis is a zoonosis acquired by eating raw or undercooked infected seafood. herein, we report a case of acute dysentery caused by anisakiasis in a 64-year-old man in malaysia. a colonoscopy was performed and a nematode larva was found penetrating the mucosa of the ascending colon. bleeding was observed at the site of penetration. y-shaped lateral epidermal cords were seen from the cross section of the worm, which is a prominent feature of anisakis larva. molecular analysis using poly ... | 2016 | 27325803 |
molecular epidemiology and risk factors for anisakis simplex s.l. infection in blue whiting (micromesistius poutassou) in a confluence zone of the atlantic and mediterranean: differences between a. simplex s.s. and a. pegreffii. | our study determined parameters of parasitization of anisakis simplex s.l. in micromesistius poutassou in a confluence zone of the atlantic and mediterranean, with a total prevalence of 82%. also, in the three seasons analyzed, high prevalence's values were found, reaching 100% in spring; however mean intensity and abundance values were higher in winter. the use of molecular techniques to differentiate between anisakis genotypes of the larvae characterized allowed obtaining values of 99.7% anisa ... | 2016 | 27289194 |
cytokine profile in patients infected with anisakis simplex in endemic areas: dietary intervention with polyphenols. a working hypothesis. | anisakiasis is a zoonosis due to infection with the nematode anisakis (a.) simplex. humans represent an accidental host after ingesting raw fish infected with a. simplex. a. simplex larvae lead to a robust host immune response mostly at gastro-intestinal level and, usually, t helper (h)2 lymphocytes play a protective against this nematode. however, larvae can elude immunity triggering activation of t regulatory (treg) cells, which, in turn, suppress th2 responses via production of interleukin (i ... | 2016 | 27150602 |
inactivation of anisakis simplex l3 in the flesh of white spotted conger (conger myriaster) by high hydrostatic pressure and its effect on quality. | koreans consume much seafood; the country is surrounded on the east, west and south by the sea. koreans have eaten raw sashimi for a long time. however, a concern in the raw sea food industry is that the parasitic nematode anisakis simplex l3 occurs naturally in marine fish. thus, the fishery industry needs a non-thermal processing method. high hydrostatic pressure (hpp) has been demonstrated to be effective. white spotted conger flesh containing 20 live larvae was exposed to different pressures ... | 2016 | 27117731 |
parasites as biological tags for stock discrimination of beaked redfish (sebastes mentella): parasite infra-communities vs. limited resolution of cytochrome markers. | the use of parasites as biological tags for discrimination of fish stocks has become a commonly used approach in fisheries management. metazoan parasite community analysis and anisakid nematode population genetics based on a mitochondrial cytochrome marker were applied in order to assess the usefulness of the two parasitological methods for stock discrimination of beaked redfish sebastes mentella of three fishing grounds in the north east atlantic. multivariate, model-based approaches demonstrat ... | 2016 | 27104735 |
ani s 11-like protein is a pepsin- and heat-resistant major allergen of anisakis spp. and a valuable tool for anisakis allergy component-resolved diagnosis. | anisakis simplex is a fish parasite responsible for gastrointestinal and allergic symptoms in humans. the ani s 11-like protein has been proposed as an anisakis allergen because its primary structure is similar to that of ani s 11. the aims of this work were to analyse the frequency of detection of the ani s 11-like protein and assess its diagnostic value. | 2016 | 27049862 |
molecular identification of anisakis and hysterothylacium larvae in commercial cephalopods from the spanish mediterranean coast. | this study aims to investigate the occurrence of nematode larvae in commercial cephalopods in the western mediterranean sea. a total of 202 animals comprising 123 broadtail shortfin squid (illex coindetii), 34 european squid (loligo vulgaris) and 45 common octopus (octopus vulgaris) were examined using enzymatic digestion. a total of 31 larvae were isolated (prevalence: 14.6%) and identified using molecular analyses which included pcr and sequencing of the its (its1-5.8s rdna-its2) region. phylo ... | 2016 | 26995720 |
prevalence of anisakid nematode larvae infecting some marine fishes from the libyan coast. | this study examined eight hundred ninety six marine fishes belonging to nine different fish species; synodus saurus; merluccius merluccius; trachurus mediterraneus; serranus cabrilla; mullus surmuletus; diplodus annularis; spicara maena; siganus rirulatus and liza ramada. the fishes were bought from fish markets at five different sites on libyan coast, from january to december 2013, for study the anisakids larvae among them. the results showed that 344/896 fishes (38.4%) were infected with anisa ... | 2015 | 26939239 |
first record of anisakis simplex third-stage larvae (nematoda, anisakidae) in european hake merluccius merluccius lessepsianus in egyptian water. | the prevalence of infection and the identification of anisakid larvae in european hake merluccius merluccius lessepsianus from hurghada city, red sea governorate, egypt, were investigated. fish samples were collected during the period of february and november 2014. twenty-two (36.66%) out of sixty examined fish specimens were found to be naturally infected with anisakis type i larvae mostly found as encapsulated larvae in visceral organs. there was a positive relationship between host length/wei ... | 2016 | 26925257 |
high prevalence of anisakis simplex hypersensitivity and allergy in sicily, italy. | anisakis simplex can elicit allergic reactions when ingested in raw or marinated fish. the prevalence of a simplex hypersensitivity and allergy in sicily (italy), an area where the consumption of raw or marinated fish is very common, has not been investigated thus far. | 2016 | 26815707 |
development of liquid chromatography-tandem mass spectrometry methods for the quantitation of anisakis simplex proteins in fish. | the parasite anisakis simplex is present in many marine fish species that are directly used as food or in processed products. the anisakid larvae infect mostly the gut and inner organs of fish but have also been shown to penetrate into the fillet. thus, human health can be at risk, either by contracting anisakiasis through the consumption of raw or under-cooked fish, or by sensitisation to anisakid proteins in processed food. a number of different methods for the detection of a. simplex in fish ... | 2016 | 26787163 |
expression of genes encoding the enzymes for glycogen and trehalose metabolism in l3 and l4 larvae of anisakis simplex. | trehalose and glycogen metabolism plays an important role in supporting life processes in many nematodes, including anisakis simplex. nematodes, cosmopolitan helminths parasitizing sea mammals and humans, cause a disease known as anisakiasis. the aim of this study was to investigate the expression of genes encoding the enzymes involved in the metabolism of trehalose and glycogen-trehalose-6-phosphate synthase (tps), trehalose-6-phosphate phosphatase (tpp), glycogen synthase (gs), and glycogen ph ... | 2015 | 26783451 |
chronic spontaneous urticaria and internal parasites--a systematic review. | chronic spontaneous urticaria (csu) is defined as persistent wheals, angioedema, or both lasting for >6 weeks due to known or unknown causes. some epidemiological studies and case reports suggest that internal parasite infections (pi) can cause csu. here, we provide a systematic overview of published findings on the prevalence and relevance of pi in csu and we discuss possible pathomechanisms. the prevalence of pi in csu was investigated by 39 independent studies and comorbidity reportedly range ... | 2016 | 26648083 |
molecular cloning and expression of a new major allergen, ani s 14, from anisakis simplex. | the nematode anisakis simplex is a representative parasite infecting marine animals. when third stage larvae of a. simplex infecting fish and squids are ingested by humans, individuals previously sensitized by this parasite may experience ige-mediated allergic reactions. so far, as many as 13 kinds of proteins (ani s 1-13) have been identified as a. simplex allergens but several more unknown allergens are suggested to exist. in this study, therefore, chemiluminescent immunoscreening of an expres ... | 2015 | 26537648 |
parasitation of sea trout (salmo trutta trutta l.) from the spawning ground and german coastal waters off mecklenburg-western pomerania, baltic sea. | a total of 52 sea trouts, salmo trutta trutta, were studied for parasites, originating from german freshwater streams and coastal waters of the baltic sea. while 35 specimens were caught mainly close to the shoreline in the baltic sea, 17 were sampled during their spawning migration in warnow river and other neighboring rivers in mecklenburg-western pomerania. a total of 12 different metazoan parasite species were found in sea trout originating from the baltic sea, including five digeneans, two ... | 2016 | 26374539 |
tolerability to dogfish in children with fish allergy. | fish is a potent food allergen. the aim of this work is to demonstrate that dogfish, a small shark, has low allergenicity in both its clinical tolerance as well as its molecular structure. | 2016 | 26337570 |
natural products: perspectives in the pharmacological treatment of gastrointestinal anisakiasis. | to evaluate the activity of different natural products against l3 larvae of anisakis type i. | 2015 | 26321513 |
nematodes parasitizing trachurus trachurus (l.) and boops boops (l.) from algeria. | a total of 455 boops boops (linnaeus, 1758) and 953 trachurus trachurus linnaeus, 1758 from the east coast of algeria were examined for their parasitic nematoda. two hundred ninety-five specimens of larval stages l3 and l4 were collected from the peritoneal cavity of these two examined fishes. photonic and scanning electronic microscopy (sem) studies were performed on these larvae specimens in order to characterize their morphology. two different species of nematoda (anisikidae) were identified: ... | 2015 | 26220559 |
aniserp: a new serpin from the parasite anisakis simplex. | serine proteinase inhibitors (serpins) finely regulate serine proteinase activity via a suicide substrate-like inhibitory mechanism. in parasitic nematodes, some serpins interact with host physiological processes; however, little is known about these essential molecules in anisakis. this article reports the gene sequencing, cloning, expression and preliminary biochemical and bioinformatically-based structural characterization of a new anisakis serpin (aniserp). | 2015 | 26215984 |
foods, drugs and environmental factors: novel kounis syndrome offenders. | kounis syndrome is hypersensitivity coronary disorder induced by various types of environmental exposures, drugs, conditions and stents. allergic, hypersensitivity, anaphylactic and anaphylactoid reactions are associated with this syndrome. the disorder manifests as coronary spasms, acute myocardial infarction and stent thrombosis and affects the cerebral and mesenteric as well as coronary arteries. importantly, its manifestations are broad and its etiology is continuously increasing. recently, ... | 2015 | 26134186 |
anisakidae in beluga whales delphinapterus leucas from hudson bay and hudson strait. | a total of 190 nematodes was isolated from the stomachs of 13 beluga whales delphinapterus leucas from the arctic part of hudson bay and hudson strait. infection intensity ranged from 1 to 57 specimens and prevalence was 84.62%. morphological examination of the nematodes revealed the presence of 3 species: pseudoterranova decipiens sensu lato, contracaecum osculatum s.l., and anisakis simplex s.l. molecular analysis by pcr-based restriction fragment length polymorphism (pcr-rflp) resulted in the ... | 2015 | 26119295 |
the complete mitochondrial genome of pseudoterranova azarasi and comparative analysis with other anisakid nematodes. | anisakiasis/anisakidosis caused by anisakid nematodes is an emerging infectious disease that can cause a wide range of clinical syndromes and are difficult to diagnose and treat in humans. in spite of their significance as pathogens, the systematics, genetics, epidemiology and biology of these parasites remain poorly understood. in the present study, we sequenced the complete mitochondrial (mt) genome of pseudoterranova azarasi, which is one of the most important zoonotic anisakid parasites. the ... | 2015 | 25998795 |
cytokine signature and antibody-mediated response against fresh and attenuated anisakis simplex (l3) administration into wistar rats: implication for anti-allergic reaction. | the third larval stage (l3) of anisakis simplex (anisakidae) is one of the zoonotic parasitic nematodes in the musculature and visceral organs of marine fishes belonging to family moronidae. the consumption of these high-commercial-value fish is widespread in many countries around the mediterranean sea including egypt. the presence of these larvae in fish muscles poses a potential consumer hazard due to the parasite's ability to cause anisakidosis. forty-two out of 60 (70%) of the european seaba ... | 2015 | 25982570 |
a case of human infection with anisakis simplex in taiwan. | | 2015 | 25963619 |
antihelmintic effects of nutmeg (myristica fragans) on anisakis simplex l3 larvae obtained from micromesistius potassou. | anisakis simplex is a foodborne pathogen that can produce human infections and allergic reactions due to the high consumption of raw fish. the seeds of myristica fragans (myristicaceae), popularly known as nutmeg, are worldwide used as a culinary spice due to its flavour and properties in food preservation. a nutmeg extract was prepared, analyzed, screened for cytotoxicity and tested against anisakis simplex l3 larvae. in order to detect the biologically active constituents of the extract, myris ... | 2015 | 25890576 |
petromyzon marinus (petromyzontidae), an unusual host for helminth parasites in western europe. | the sea lamprey petromyzon marinus, which is among the most phylogenetically ancient vertebrates, is a hematophagous ectoparasite that feeds on vertebrates and is considered vulnerable in europe but is a pest in the north american great lakes. we conducted a literature review of helminth parasites of p. marinus and investigated postmetamorphic lampreys sampled in rivers and northeast atlantic coastal waters (western france) during spawning migration. based on the literature review, 16 helminth t ... | 2015 | 25850404 |
in vivo and in vitro testing with rani s 1 can facilitate diagnosis of anisakis simplex allergy. | traditional diagnostic tests such as skin prick tests (spt) and specific ige (slge) against whole anisakis simplex extract have low specificity. consequently, allergy to a simplex is overdiagnosed. | 2014 | 25668895 |
fish-allergic patients may be able to eat fish. | reported fish allergy prevalence varies widely, with an estimated prevalence of 0.2% in the general population. sensitization to fish can occur by ingestion, skin contact or inhalation. the manifestations can be ige or non-ige mediated. several fish allergens have been identified, with parvalbumins being the major allergen in various species. allergenicity varies among fish species and is affected by processing or preparation methods. adverse reactions after eating fish are often claimed to be ' ... | 2015 | 25666551 |
[two cases of allergies due to anisakis simplex, positive to specific ige for ani s 12 allergen]. | we report 2 cases of immediate allergies to anisakis after ingestion of seafood. in case 1, after ingestion of flatfish, sea bream and mackerel, wheals and dyspnea occurred. result of immunocap was class 5 for anisakis. elisa for specific ige showed that the patient serum strongly reacted to ani s 12. in case 2, after ingestion of flatfish and yellowtail, pruritus and dyspnea occurred. result of immunocap was class 6 for anisakis. elisa for specific ige showed that the patient serum reacted to a ... | 2014 | 25634460 |
tlr2-dependent amelioration of allergic airway inflammation by parasitic nematode type ii mif in mice. | in our previous studies, the recombinant type ii macrophage migration inhibitory factor homologue (ras-mif) secreted from anisakis simplex suppressed experimental inflammation mouse model through il-10 production and cd4(+)cd25(+)foxp3(+) t-cell recruitment. also, tlr2 gene expression was significantly increased following ras-mif treatment. to know the relation between tlr2 and amelioration mechanisms of ras-mif, we induced allergic airway inflammation by ovalbumin and alum with or without ras-m ... | 2015 | 25559209 |
anisakid nematodes in beaked redfish (sebastes mentella) from three fishing grounds in the north atlantic, with special notes on distribution in the fish musculature. | parasitic anisakid nematodes commonly occur in the musculature and visceral organs of many fish species from the north atlantic. in this respect, the presence of the third stage larvae of anisakis spp. in the fish musculature may pose a potential consumer hazard due to the parasite's ability to cause anisakidosis. thus, knowledge on the occurrence and distribution of these potentially zoonotic parasites in the commercially important north atlantic fish species is crucial in order to evaluate and ... | 2015 | 25498327 |
relationships between t cell and ige/igg4 epitopes of the anisakis simplex major allergen ani s 1. | anisakiasis is a global disease caused by the consumption of raw or lightly cooked fish parasitized with third-stage anisakis larvae. anisakis simplex allergens may cause severe allergic reactions including angio-oedema, urticaria and anaphylaxis. approximately 80% of allergic patients have allergen-specific ige against ani s 1, and the diagnostic value of testing for antibodies to ani s 1 has been extensively demonstrated. however, no previous studies have investigated the molecular aspects of ... | 2015 | 25495594 |
removal of anisakis simplex allergens from infected fish during the washing step of surimi production. | the washing operation of fish muscle is one of the key steps in the production of surimi. the aim of this study was to assess in parasitised minced fish the effect of the washing steps on the allergen removal of anisakis simplex and on protein yield during surimi processing. experimentally infected hake (merluccius merluccius) (50 anisakis simplex s.s l3 larvae per 100 g of muscle) underwent three successive washing steps with water, phosphate buffer (20 mmol l(-1) ), sodium bicarbonate (60 mmol ... | 2015 | 25378259 |
allergenicity of two anisakis simplex allergens evaluated in vivo using an experimental mouse model. | anisakis (anisakidae) is one of the most important causes of helminth-induced allergic reactions and elicits clinical responses that include urticaria, rhinitis, bronco-constriction, cough, and/or gastrointestinal symptoms. more than 13 reactive allergens have been identified in the serum of anisakis allergy patients, but the allergenicity of only a few of these have been evaluated in vivo using a mouse model. to evaluate the allergenicity of two important allergens, ani s 1 and ani s 9, we indu ... | 2014 | 25300761 |
putative hybrids between two anisakis cryptic species: molecular genotyping using high resolution melting. | the genus anisakis includes nine recognized species and the complex of cryptic species anisakis simplex s. l. is often associated with the human disease known as anisakiasis. during the last decades the use of nuclear ribosomal its allowed the identification and description of numerous anisakid nematodes and the discovery of recombinant genotypes or putative hybrids even in other parasitic helminths, such as those between a. simplex sensu stricto and a. pegreffii. the existence of pure hybrids o ... | 2014 | 25241034 |
occurrence of zoonotic nematodes pseudoterranova decipiens, contracaecum osculatum and anisakis simplex in cod (gadus morhua) from the baltic sea. | baltic cod gadus morhua (a total of total 224 specimens) captured east of the island of bornholm in the southern baltic sea were subjected to a parasitological investigation between march 2013 and april 2014. full artificial digestion of fillets from 188 cod and additional investigation of livers from 36 cod were performed. cod or seal worm pseudoterranova decipiens was recorded in musculature (prevalences up to 55% and intensities up to 56 worms per fish) associated with a negative correlation ... | 2014 | 25224792 |
[anisakis simplex larvae: infection status in marine fishes for sale in shantou]. | to investigate the infection status of anisakis simplex larvae in marine fishes for sale in shantou. | 2014 | 25223058 |
anisakids (nematoda: anisakidae) from stomachs of northern fur seals (callorhinus ursinus) on st. paul island, alaska: parasitological and pathological analysis. | anisakid nematodes parasitize the alimentary tracts of aquatic vertebrates, including northern fur seals (callorhinus ursinus) (nfs). the main purpose of this study was to estimate the prevalence, intensity, and species composition of anisakids in nfss on st. paul island, alaska, and to analyze changes in nfs infection with these nematodes during the last decades. the study was carried out on st. paul island, alaska, in july-august 2011-2013. stomachs of 443 humanely harvested nfs males were col ... | 2014 | 25216781 |
metazoan parasites from herring (clupea harengus l.) as biological indicators in the baltic sea. | zoographical distribution of metazoan fish parasites in herring, clupea harengus, from the baltic sea was analysed in order to use them as potential biological indicators. a total of 210 herring from six different sampling sites were investigated, harbouring 12 different parasite species [five digeneans (d), one cestode (c), three nematodes (n) and three acanthocephalans (a)]. the distribution of the parasite species differed according to region, with a distinct gradient of decreasing species ri ... | 2014 | 25119368 |
positive associations between infections of toxoplasma gondii and seropositivity with anisakis simplex in human patients suffering from chronic urticaria. | toxoplasma gondii is a food-borne and orofecal microorganism which produces chronic infection, and attempts have been made to prove its negative association with atopy in the context of the hygiene hypothesis. anisakis simplex is a fish parasite associated with chronic urticaria (cu) in endemic regions. we analysed the relationship between both infectious agents in cu. we included 42 patients with chronic urticaria (18 patients with cu associated with a. simplex sensitization and 24 not sensitiz ... | 2015 | 24991841 |
activity of tea tree (melaleuca alternifolia) essential oil against l3 larvae of anisakis simplex. | nematicidal activity of melaleuca alternifolia essential oil, commonly known as tea tree oil (tto), was assayed in vitro against l3 larvae of anisakis simplex. the results showed a mortality of 100% for concentrations between 7 and 10 μl/ml after 48 h of incubation, obtaining an ld50 value of 4.53 μl/ml after 24 hours and 4.27 μl/ml after 48 hours. concentration-dependent inhibition of acetylcholinesterase was observed for tea tree essential oil showing inhibition values of 100% at 100 μl/ml. th ... | 2014 | 24967378 |
occurrence of anisakis simplex sensu stricto in imported atlantic mackerel (scomber scombrus) represents a risk for turkish consumers. | anisakid larvae are a prevalent food-borne pathogen that has been found in numerous fish species destined for human consumption. the accidental consumption of infected raw or poorly cooked fish may cause gastroenteric diseases and allergies in humans. in spite of the fact that thorough cooking or freezing kills anisakis worms, this method does not destroy their allergenic capacity. the presence of a. simplex (s.s.) in seafood products may present a health risk for consumers. in turkey, atlantic ... | 2014 | 24935687 |
anisakis/ascaris ige ratio improves specificity for the diagnosis of anisakis simplex sensitization in travellers and immigrants. | anisakis simplex is a fish parasite responsible for human infection and is able to induce ige-mediated reactions with several clinical manifestations. laboratory diagnosis of anisakis allergy is based on the detection of specific ige using parasite whole antigen. unfortunately, these diagnostic tools detect cross-reactivities with other nematodes and micro-organisms leading to low specificity of the diagnostic tests. the aim of this retrospective study was to assess the diagnostic value of speci ... | 2014 | 24911935 |
antigenicity of anisakis simplex s.s. l3 in parasitized fish after heating conditions used in the canning processing. | some technological and food processing treatments applied to parasitized fish kill the anisakis larvae and prevent infection and sensitization of consumers. however, residual allergenic activity of parasite allergens has been shown. the aim here was to study the effect of different heat treatments used in the fish canning processing industry on the antigen recognition of anisakis l3. bigeye tuna (thunnus obesus) and yellowfin tuna (thunnus albacares) were experimentally infected with live l3 ani ... | 2015 | 24888867 |
proteomic profiling and characterization of differential allergens in the nematodes anisakis simplex sensu stricto and a. pegreffii. | the parasite species complex anisakis simplex sensu lato (anisakis simplex sensu stricto; (a. simplex s.s.), a. pegreffii, a. simplex c) is the main cause of severe anisakiasis (allergy) worldwide and is now an important health matter. in this study, the relationship of this anisakis species complex and their allergenic capacities is assessed by studying the differences between the two most frequent species (a. simplex s.s., a. pegreffii) and their hybrid haplotype by studying active l3 larvae p ... | 2014 | 24723494 |
acetylcholinesterase secreted by anisakis simplex larvae (nematoda: anisakidae) parasitizing herring, clupea harengus: an inverse relationship of enzyme activity in the host-parasite system. | acetylcholinesterase (ache) is a key enzyme involved in nerve impulse transmission in both vertebrates and invertebrates. in addition to neuromuscular ache, many parasitic nematodes synthesize ache in secretory glands and release the enzyme into their external environment. in this study, we evaluate the activities of both somatic and secreted ache from larvae (l3) of the parasitic nematode anisakis simplex, and compare these to the ache activity in its host, herring, clupea harengus. a. simplex ... | 2014 | 24705520 |
identification of autoclave-resistant anisakis simplex allergens. | anisakis simplex is a fish parasite able to induce allergic reactions in humans infected when eating raw or undercooked fish parasitized with viable third-stage larvae. some authors claim that exposure to nonviable anisakis material can result in allergic symptoms in previously sensitized patients, indicating that parasite allergens are resistant to the thermal treatments of usual cooking procedures. furthermore, some patients report symptoms after eating canned fish. the aim of this work was th ... | 2014 | 24680072 |
relationships between ige/igg4 epitopes, structure and function in anisakis simplex ani s 5, a member of the sxp/ral-2 protein family. | anisakiasis is a re-emerging global disease caused by consumption of raw or lightly cooked fish contaminated with l3 anisakis larvae. this zoonotic disease is characterized by severe gastrointestinal and/or allergic symptoms which may misdiagnosed as appendicitis, gastric ulcer or other food allergies. the anisakis allergen ani s 5 is a protein belonging to the sxp/ral-2 family; it is detected exclusively in nematodes. previous studies showed that sxp/ral-2 proteins are active antigens; however, ... | 2014 | 24603892 |
helminth allergens, parasite-specific ige, and its protective role in human immunity. | the th2 immune response, culminating in eosinophilia and ige production, is not only characteristic of allergy but also of infection by parasitic worms (helminths). anti-parasite ige has been associated with immunity against a range of helminth infections and many believe that ige and its receptors evolved to help counter metazoan parasites. allergens (ige-antigens) are present in only a small minority of protein families and known ige targets in helminths belong to these same families (e.g., ef ... | 2014 | 24592267 |
anthelmintic activities of aporphine from nelumbo nucifera gaertn. cv. rosa-plena against hymenolepis nana. | nelumbo nucifera gaertn. cv. rosa-plena (nelumbonaceae), commonly known as lotus, is a perennial aquatic plant grown and consumed throughout asia. all parts of n. nucifera have been used for various medicinal purposes in oriental medicine. from the leaves of nelumbo nucifera gaertn. cv. rosa-plena (an aquatic plant), liriodenine (1), lysicamine (2), (-)-anonaine (3), (-)-asimilobine (4), (-)-caaverine (5), (-)-n-methylasimilobine (6), (-)-nuciferine (7), (-)-nornuciferine (8), (-)-roemerine (9), ... | 2014 | 24583851 |
oral inoculation of live or dead third-stage larvae of anisakis simplex in rats suggests that only live larvae induce production of antibody specific to a. simplex. | live anisakis simplex third-stage larvae (l3) penetrate gastrointestinal mucosa after they are ingested in raw or undercooked seafood, thereafter causing gastrointestinal manifestations and allergic manifestations such as urticaria and anaphylaxis. these allergic reactions are mediated by specific ige to l3 allergens, especially excretory-secretory (es) allergens. recent evidences suggest that only live larvae can cause allergic reactions, although cases attributable to ingestion of cooked, froz ... | 2014 | 24570066 |
anisakids of seals found on the southern coast of baltic sea. | in the present study 5 grey seals (halichoerus grypus), 3 common seals (phoca vitulina) and 1 ringed seal (pusa hispida) bycaught or stranded on the polish baltic sea coast in years 2000-2006 were investigated for the infestation of parasitic anisakid nematodes. 749 of anisakids were found. the most common were: contracaecum osculatum (59.3%) and pseudoterranova decipiens (31.0%). there were also small numbers of anisakis simplex (0.8%). after performing rflp three sibling species were found. c. ... | 2014 | 24570064 |
cross-reactivity between anisakis spp. and wasp venom allergens. | anisakiasis is caused by the consumption of raw or undercooked fish or cephalopods parasitized by live l3 larvae of nematode anisakis spp. larvae anchor to stomach mucosa releasing excretion/secretion products which contain the main allergens. it has been described that nematode larvae release venom allergen-like proteins among their excretion/secretion products. we investigated potential cross-reactivity between anisakis and wasp venom allergens. | 2014 | 24525615 |
gastrointestinal parasites of bottlenose dolphins tursiops truncatus from the extreme southwestern atlantic, with notes on diet composition. | we surveyed the gastrointestinal tracts of 6 bottlenose dolphins tursiops truncatus from patagonia to check for helminth parasites and characterize dolphin diet. all dolphins harbored parasites (6477 helminths). we recorded 7 species, including nematodes anisakis simplex s.l., pseudoterranova decipiens, acanthocephalans corynosoma cetaceum, c. australe, and digeneans braunina cordiformis, pholeter gastrophilus and synthesium tursionis. among the gastric helminths, the most prevalent species were ... | 2014 | 24492055 |
an in vitro study of lipid preference in whaleworm (anisakis simplex, nematoda, ascaridoidea, anisakidae) third-stage larvae. | the behavioural response of nematodes to chemical stimuli has been extensively investigated in some free-living and plant parasitic species. however, in animal parasitic species, little is yet known, particularly in regards to marine forms such as the whaleworm (anisakis simplex). previous studies showed that a. simplex l3-larvae tend to prefer fish tissue with high lipid content. the intention of this study was to investigate the behaviour of a. simplex l3 in response to different concentration ... | 2014 | 24458651 |
the complete mitochondrial genome of toxascaris leonina: comparison with other closely related species and phylogenetic implications. | adults of toxascaris leonina (nematoda: ascarididae) live in the gastrointestinal tract of both dogs and cats, and cause significant economic losses and potential public health problem worldwide. although many studies have given insights into this significant pathogen, to date, the complete mitochondrial (mt) genome sequence is still not available for t. leonina. here, we sequenced the complete mt genome of t. leonina. this at-rich (71.53%) mt genome (14,310bp) is circular and consists of 36 gen ... | 2014 | 24316156 |
genetic and morphological approaches distinguish the three sibling species of the anisakis simplex species complex, with a species designation as anisakis berlandi n. sp. for a. simplex sp. c (nematoda: anisakidae). | numerous specimens of the 3 sibling species of the anisakis simplex species complex (a. pegreffii, a. simplex (senso stricto)), and a. simplex sp. c) recovered from cetacean species stranded within the known geographical ranges of these nematodes were studied morphologically and genetically. the genetic characterization was performed on diagnostic allozymes and sequences analysis of nuclear (internal transcribed spacer [its] of ribosomal [r]dna) and mitochondrial (mitochondrial [mt]dna cox2 and ... | 2014 | 24224764 |
an extended study of seroprevalence of anti-anisakis simplex ige antibodies in norwegian blood donors. | during the last decade, cases of the fish parasite anisakis simplex infection and allergy in human have increased in countries with high fish consumption. our aim was to perform an extended seroprevalence study of anti-ige antibodies against this parasite in norway, one of the high fish-consuming countries. at the department of immunology and transfusion medicine and the laboratory of clinical biochemistry, haukeland university hospital, bergen, norway, two main groups of anonymized serum sample ... | 2014 | 24219706 |
specific igg4: possible role in the pathogenesis and a new marker in the diagnosis of anisakis-associated allergic disease. | igg4 and ige are immunoglobulin isotypes which are mediated by the same th2-mediated mechanism. the postulated pathogenic and protective function of ige or igg4, respectively, in allergic disease is opposite in parasitic infection. the possible role of igg4 against recombinant major allergens on the appearance of different forms of anisakis simplex-associated allergic disease was studied. gastro-allergic anisakiasis (gaa) and anisakis-sensitization-associated chronic urticaria (cu+) were compare ... | 2014 | 24219647 |
mitochondrial genomes of anisakis simplex and contracaecum osculatum (sensu stricto)--comparisons with selected nematodes. | anisakid nematodes parasitize mainly fish, marine mammals and/or fish-eating birds, and can be transmitted to a range of fish-eating mammals, including humans, where they can cause gastrointestinal disease linked to larval infection or allergic responses. in spite of the animal and human health significance of these parasites, there are still gaps in our understanding of the systematics, biology, epidemiology and ecology of anisakids. mitochondrial (mt) dna provides useful genetic markers for in ... | 2014 | 24211683 |
[recognition of excretory/secretory antigens of anisakis type i and evolution of ige in experimentally infected rats]. | anisakis spp., during parasitism, release excretory-secretory antigens that, in contact with the human immune system, can trigger a hypersensitivity response mediated by ige, causing various allergic symptoms. | 2014 | 24211134 |
[parasitic nematodes of fish in the coastal waters of gökçeada]. | the aim of this study is to determine the parasitic nematodes of fish near gökçeada, their host and infection values. | 2013 | 24192623 |
antioxidant, anti-adipocyte differentiation, antitumor activity and anthelmintic activities against anisakis simplex and hymenolepis nana of yakuchinone a from alpinia oxyphylla. | alpinia oxyphylla is a common remedy in traditional chinese medicine. yakuchinone a is a major constituent of a. oxyphylla and exhibits anti-inflammatory, antitumor, antibacterial, and gastric protective activities. | 2013 | 24070160 |
expression of immune relevant genes in rainbow trout following exposure to live anisakis simplex larvae. | basic immune response mechanisms in vertebrates against helminths are still poorly understood. fish-nematode models may prove valuable for elucidation of this question. in this study we orally challenged rainbow trout (oncorhynchus mykiss) with larvae of anisakis simplex (nematoda: anisakidae) and subsequently investigated the expression of 18 immune relevant genes in spleen and liver 1, 4 and 8days post infection (d.p.i.). gene expression data were analysed with regard to the infection status o ... | 2013 | 24051344 |
cross-sectional study of serum reactivity to anisakis simplex in healthy adults in niterói, brazil. | although the incidence of anisakiasis is rising worldwide, its frequency is still unknown in brazil. the aim of this study was to verify immunoreactivity to anisakis simplex antigens in healthy adults and determine its possible relationship with frequency of fish consumption and allergy symptoms. a prospective cross-sectional study was carried out with 67 volunteers recruited from a military facility in niterói, brazil. the subjects completed a structured questionnaire and serum titers of specif ... | 2013 | 23990439 |
is anisakis simplex s.l. a biological marker for stock identification of strangomera bentincki from chile? | the absence of the larval anisakis simplex s. l. in samples from central chile but heavy infections in fish from southern localities suggest the existence of two stocks of strangomera bentincki, one closely associated with the central coast of chile (landing port san antonio and talcahuano, c. 33° 30' s-36° 40' s) and the other associated with southern chile (landing port puerto montt, c. 41° 30' s). results confirm the usefulness of metazoan parasites, like a. simplex s. l. as biological marker ... | 2013 | 23902315 |
experimental infection of mice with anisakis simplex. | | 2013 | 23856880 |
anisakis, just think about it in an emergency! | a few years ago, anisakis infection was almost unknown. since the first observation in the netherlands in 1960, several cases of gastrointestinal infections due to a zoonosis sustained by this nematode have been described in countries in which the consumption of raw or uncooked fish (e.g., marinated or salted) is common. japan alone accounts for 90% of all cases of anisakiasis described in the literature because of the widespread use of raw fish in traditional japanese cuisine, with sushi and sa ... | 2013 | 23850538 |
[role of helminth antigens in the abnormal mitosis of bone marrow cells in laboratory animals]. | the intraabdominal administration of somatic extracts of the cestodes hydatigera taeniaformis batsch 1786, lamarck, 1816 and diphyllobothrium latum linnaeus, 1758 and the nematodes anisakis simplex larva rudolphi 1809, toxocara canis railliet et henry, 1912 in albino mice proved that these helminths had a karyopathic effect on the bone marrow cells of the animals. the antigenic composition of these extracts was investigated using the agar gel immunodiffusion test. the antigenic composition of th ... | 2015 | 25924282 |
intestinal anisakiasis as a rare cause of small bowel obstruction. | anisakiasis, a parasitic infection by larvae of the nematode anisakis found in raw or undercooked saltwater fish, mostly involves stomach but rarely small intestine. we report a rare case of a 61-year-old man who presented with abdominal pain and developed small bowel obstruction caused by intestinal anisakiasis. abdominal computed tomography revealed segmental edema of the intestinal wall with proximal dilatation. the patient underwent urgent laparotomy because strangulated small bowel obstruct ... | 2013 | 23786678 |
effects of excretory/secretory products from anisakis simplex (nematoda) on immune gene expression in rainbow trout (oncorhynchus mykiss). | excretory/secretory (es) products are molecules produced by parasitic nematodes, including larval anisakis simplex, a parasite occurring in numerous marine fish hosts. the effects of these substances on host physiology have not been fully described. the present work elucidates the influence of es substances on the fish immune system by measuring immune gene expression in spleen and liver of rainbow trout (oncorhynchus mykiss) injected intraperitoneally with es products isolated from a. simplex t ... | 2013 | 23769875 |
avidity studies in anisakis simplex-associated allergic diseases. | gastroallergic anisakiasis (gaa) and anisakis-sensitization-associated chronic urticaria (cu+) differ with respect to specific ige levels. we hypothesised different immunoglobulin avidities in both entities as well as their dependence on ti and fish consumption. 16 patients with gaa and 17 patients with cu+ were included, and immunoglobulin levels were analysed by cap (phadia). ige and igg avidity indexes (avige and avigg, resp.) were also determined. igg avidity was higher in gaa than in cu+ (p ... | 2013 | 23762082 |
comparative infectivity of three larval nematode species in three different salmonids. | host specificity of parasites may depend both on ecological and physiological factors. basic descriptions of the susceptibility/resistance of fish to specific nematodes are needed in order to reveal mechanisms in the host-parasite relation. rainbow trout (oncorhynchus mykiss), brown trout (salmo trutta), and atlantic salmon (salmo salar) were orally infected with larval stages of three different anisakid nematodes-hysterothylacium aduncum, contracaecum osculatum, and anisakis simplex-and parasit ... | 2013 | 23733234 |
global assessment of molecularly identified anisakis dujardin, 1845 (nematoda: anisakidae) in their teleost intermediate hosts. | here, we present the its ribosomal dna (rdna) sequence data on 330 larvae of nematodes of the genus anisakis dujardin, 1845 collected from 26 different bony fish species from 21 sampling locations and different climatic zones. new host records are provided for anisakis simplex (rudolphi, 1809) sensu stricto (s.s.) and a. pegreffli campana-rouget et biocca, 1955 from anoplopoma fimbria (pallas) (santa barbara, east pacific), a. typica (diesing, 1860) from caesio cuning (bloch), lepturacanthus sav ... | 2013 | 23724731 |
anisakis simplex: a new etiological agent of kounis syndrome. | | 2013 | 23639458 |
unusual cause of small intestine obstruction in a child: small intestine anisakiasis: report of a case. | anisakiasis is caused by human infection by the anisakis larvae, a marine nematode found in undercooked or raw fish. infection with the parasite anisakis simplex is common in japan and northern european countries. with the increased popularity of eating sushi and raw fish infection with anisakis is expected to rise. | 2013 | 23596037 |
relationship between red vent syndrome and anisakid larvae burden in wild atlantic salmon (salmo salar). | the pathogenesis of the recently recognized "red vent syndrome" in wild atlantic salmon (salmo salar) is not fully understood. pathologic observations indicate that this syndrome is associated with the presence of nonencapsulated larvae of the nematode anisakis simplex in the body wall, the lower intestinal wall, and the visceral cavity surrounding the vent region. we evaluated the relationship between the occurrence of red vent syndrome and intensity of infection with anisakis sp. larvae in nat ... | 2013 | 23568898 |
brazilein from caesalpinia sappan l. antioxidant inhibits adipocyte differentiation and induces apoptosis through caspase-3 activity and anthelmintic activities against hymenolepis nana and anisakis simplex. | brazilein, a natural, biologically active compound from caesalpinia sappan l., has been shown to exhibit anti-inflammatory and antioxidant properties and to inhibit the growth of several cancer cells. this study verifies the antioxidant and antitumor characteristics of brazilein in skin cancer cells and is the first time to elucidate the inhibition mechanism of adipocyte differentiation, cestocidal activities against hymenolepis nana, and reduction of spontaneous movement in anisakis simplex. br ... | 2013 | 23554834 |
anisakid nematodes of greenland halibut reinhardtius hippoglossoides from the barents sea. | parasitic nematodes from the body cavity of 94 greenland halibut (reinhardtius hippoglossoides) caught in the barents sea were examined. nematode species were identified using both morphological and molecular methods. four morphospecies were found: anisakis simplex s.l., contracaecum osculatum s.l., pseudoterranova decipiens s.l., and hysterothylacium aduncum. the most prevalent were c. osculatum s.l. (89.4%) and a. simplex s.l. (86.2%). mean intensities for these 2 species were 7.8 and 45.2, re ... | 2013 | 23536987 |
presence of anisakis simplex (rudolphi, 1809 det. krabbe, 1878) and hysterothylacium aduncum (rudolphi, 1802) (nematoda; anisakidae) in runts of farmed atlantic salmon, salmo salar l. | one hundred farmed atlantic salmon, salmo salar l., were examined for the presence of nematodes by digestion of tissue in hcl-pepsin solution. all fish were sampled from one cage in a fish farm on the norwegian south-west coast. fifty harvest quality salmon, that is, salmon for human consumption (mean 5.4 kg, variation 3.0-7.6 kg), were sampled at the processing line while 50 salmon runts (mean 1.1 kg, variation 0.4-1.8 kg), discarded due to poor performance, were sampled from the discard bin af ... | 2014 | 23488892 |
different fish-eating habits and cytokine production in chronic urticaria with and without sensitization against the fish-parasite anisakis simplex. | anisakis simplex sensitization has been associated with acute, but also with chronic urticaria. the objective of this study is to characterize chronic urticaria with (cu+) and without sensitization (cu-) against the ubiquitous fish parasite a. simplex in a transversal and longitudinal evaluation. | 2013 | 23435560 |
larval anisakid infections in marine fish from three sea areas of the republic of korea. | the present study was performed to determine the infection status of anisakid larvae in marine fish collected from 3 sea areas of the republic of korea. total 86 marine fish (8 species) collected from the east sea (goseong-gun, gangwon-do), 171 fish (10 species) from the south sea (sacheon-si, gyeongsangnam-do), and 92 fish (7 species) from the yellow sea (incheon metropolitan city) were examined by both naked eyes and artificial digestion method. among the total of 349 fish examined, 213 (61.0% ... | 2012 | 23230326 |
anisakis simplex hypersensitivity is associated with chronic urticaria in endemic areas. | chronic urticaria (cu) may affect up to 1% of the general population. anisakis simplex hypersensitivity is frequent in areas where raw fish is consumed and a. simplex allergy represents a relevant cause of acute urticaria. we assessed the possible association between cu and a. simplex sensitization in an area where marinated fish is very frequently eaten. | 2013 | 23095317 |
anisakis simplex: current knowledge. | anisakiasis, firstly described in 1960s in the netherlands, is a fish-borne parasitic disease caused by the consumption of raw or undercooked fish or cephalopods contaminated by third stage (13) larvae of the anisakidae family, in particular anisakis simplex (as), a. pegreffii and pseudoterranova decipiens. every year, approximately 20,000 cases of anisakiasis were reported worldwide, over 90% are from japan and most others in spain, the netherlands and germany, depending on the habits of fish c ... | 2012 | 23092000 |
[a case of an allergic reaction due to anisakis simplex possibly after the ingestion of squid--successful detection of four a. simplex allergens, ani s 1, ani s 2, ani s 12 and troponin c-like protein]. | a 62-year-old man ingested dressed salmon and its roe (ikura) and grilled mackerel and one hour later further ingested raw tuna and squid as an evening meal at a bar. soon after the ingestion of raw seafood, he showed wheals, loss of consciousness and low blood pressure. specific serum ige to the nematode anisakis simplex was positive but those to some seafoods were negative. moreover, a skin prick test using the crude extract was positive for a. simplex but negative for the seafoods, which he i ... | 2012 | 23089975 |
stereo and scanning electron microscopic studies of the third stage larvae of anisakis simplex. | this study was to demonstrate the surface anatomy of the third stage larvae of anisakis simplex in marine fish using stereo and scanning electron microscopes (sem). the round worm is slender, elongated and of cylindrically shaped. the head of this worm is a globular structure. the mouth is triangularly shaped and surrounded by three lips. a boring tooth projects dorsally at the anterior end. there are four pairs of tactoreceptors, the labial papillae, enclosing the lips. the tail end is blunt an ... | 2012 | 23082581 |
risk analysis of human anisakidosis through the consumption of the blue whiting, micromesistius poutassou, sold at spanish supermarkets. | european legislation directed at the catering industry concerning the prevention of anisakidosis proposes efficient measures to avoid human infestation, but this legislation does not directly address the consumer at the household level. assessing the anisakidosis risk for consumers who buy fresh fish at supermarkets in spain, 284 blue whiting, micromesistius poutassou, specimens, originating from two fishing zones and seasons of capture, sold at five nationwide spanish supermarket chains, were e ... | 2012 | 23035727 |
prevalence of zoonotic anisakid nematodes in inuit-harvested fish and mammals from the eastern canadian arctic. | human anisakidosis is a recognized arctic zoonosis that is directly related to the consumption of traditional inuit foods, particularly raw fish. the epidemiology of infections with the zoonotic anisakid nematodes anisakis simplex and pseudoterranova decipiens was investigated from august 2007 to july 2009 in inuit-harvested fish and marine mammals from inuit regions of nunavik, nunavut, and nunatsiavut, canada. fish were tested for anisakid larvae using the pepsin-hcl digestion method, and the ... | 2012 | 22957974 |
microhabitat preference of anisakis simplex in three salmonid species: immunological implications. | three salmonid fish species, oncorhynchus mykiss, salmo salar and salmo trutta, were infected experimentally with the parasitic nematode anisakis simplex (a. simplex) and the difference between in vivo behaviour of the nematode in the three fish species was investigated. infection success rate differed between species. s. salar (baltic salmon) showed the highest number of successfully established nematodes, whereas s. trutta (brown trout) and o. mykiss (rainbow trout) had a higher natural resist ... | 2012 | 22858638 |
spontaneous splenic rupture and anisakis appendicitis presenting as abdominal pain: a case report. | anisakidosis, human infection with nematodes of the family anisakidae, is caused most commonly by anisakis simplex. acquired by the consumption of raw or undercooked marine fish or squid, anisakidosis occurs where such dietary customs are practiced, including japan, the coastal regions of europe and the united states. rupture of the spleen is a relatively common complication of trauma and many systemic disorders affecting the reticuloendothelial system, including infections and neoplasias. a rar ... | 2012 | 22524971 |
prevalence of sensitization to anisakis simplex among professionally exposed populations in sicily. | anisakis simplex (as) is a cause of allergic sensitization and potential occupational risk is suggested in fishermen and workers assigned to fish processing and sale. a cross-sectional study was conducted in order to assess possible health effects of occupational exposure to as in workers recruited from western sicily fisheries sector. social, demographic, and occupation-related data were collected. serum total immunoglobulin e (ige) and specific ige levels to as (threshold >0.35 ku/l) were dete ... | 2012 | 22524649 |