| time course of changes in heart rate and sympathetic tone after coronary artery ligation in rats. | the purpose of this study was to investigate the changes of heart rate (hr) and sympathetic tone occurring after myocardial infarction. male rats (200-250 g) were submitted to ligation of the anterior branches of the left coronary artery to produce infarction (inf, n = 26) or to sham surgery (so, n = 24). groups of animals (n = 6-8) were studied 1,3,7 and 15 days later. a group not submitted to surgical procedures was used as control (c,n = 6). blood pressure and hr were measured in conscious un ... | 1991 | 1797278 |
| memory modulation by brain benzodiazepines. | 1. recent evidence indicates that post-training memory processes are down-regulated by benzodiazepine/gaba-a systems in the amygdala, septum and hippocampus. habituation and avoidance learning are accompanied by a decrease of benzodiazepine-like immunoreactivity in the three structures, explainable by a release of benzodiazepines. immediate post-training microinjection of the benzodiazepine antagonist flumazenil into the hippocampus enhances retention of habituation. the post-training administra ... | 1991 | 1797279 |
| memory modulation by brain benzodiazepines. | 1. recent evidence indicates that post-training memory processes are down-regulated by benzodiazepine/gaba-a systems in the amygdala, septum and hippocampus. habituation and avoidance learning are accompanied by a decrease of benzodiazepine-like immunoreactivity in the three structures, explainable by a release of benzodiazepines. immediate post-training microinjection of the benzodiazepine antagonist flumazenil into the hippocampus enhances retention of habituation. the post-training administra ... | 1991 | 1797279 |
| renovascular hypertension impairs formation of endothelium-derived relaxing factors and sensitivity to endothelin-1 in resistance arteries. | 1. endothelium-dependent vascular regulation was investigated in mesenteric resistance arteries of goldblatt two kidney-one clip (2k1c) renovascular hypertensive rats. 2. third order branches of mesenteric arteries were dissected free and mounted on glass cannulae in an organ chamber. changes in vascular diameter were measured in pressurized and perfused arteries with a video dimension analyzer. 3. acetylcholine evoked endothelium-dependent relaxations that were much more pronounced with intralu ... | 1991 | 1797302 |
| renovascular hypertension impairs formation of endothelium-derived relaxing factors and sensitivity to endothelin-1 in resistance arteries. | 1. endothelium-dependent vascular regulation was investigated in mesenteric resistance arteries of goldblatt two kidney-one clip (2k1c) renovascular hypertensive rats. 2. third order branches of mesenteric arteries were dissected free and mounted on glass cannulae in an organ chamber. changes in vascular diameter were measured in pressurized and perfused arteries with a video dimension analyzer. 3. acetylcholine evoked endothelium-dependent relaxations that were much more pronounced with intralu ... | 1991 | 1797302 |
| [hematological abnormalities in acute viral hepatitis and acute hepatitis in hbsag carrier]. | various kinds of hematological abnormalities have been known to occur in liver diseases. to understand the hematological changes in acute viral hepatitis, 324 adults with acute viral hepatitis were studied. of them, 3 were acute hepatitis a, 91 acute hepatitis b, 99 acute non-a, non-b hepatitis (nanb) and 181 acute hepatitis on chronic hepatitis b (ah on ch-b). there were 233 males and 91 females; age ranged from 16 to 74 years (mean age 39 years.) the results showed the incidences of thrombocyt ... | 1991 | 1797369 |
| [hematological abnormalities in acute viral hepatitis and acute hepatitis in hbsag carrier]. | various kinds of hematological abnormalities have been known to occur in liver diseases. to understand the hematological changes in acute viral hepatitis, 324 adults with acute viral hepatitis were studied. of them, 3 were acute hepatitis a, 91 acute hepatitis b, 99 acute non-a, non-b hepatitis (nanb) and 181 acute hepatitis on chronic hepatitis b (ah on ch-b). there were 233 males and 91 females; age ranged from 16 to 74 years (mean age 39 years.) the results showed the incidences of thrombocyt ... | 1991 | 1797369 |
| synthesis of 4- and 5-amino-1-(2-deoxy-d-erythro-pentofuranosyl)imidazole nucleosides by chemical and biotransformation methods. | (2-deoxy-d-erythro-pentofuranosyl)imidazole nucleosides have been synthesised by glycosylation of the sodium salt of ethyl 5-aminoimidazole-4-carboxylate with 2-deoxy-3,5-di-o-p-toluoyl-alpha-d-erythro-pentofuranosyl chloride. glycosylation of ethyl 5-aminoimidazole-4-carboxylate with 2-deoxy-beta-d-erythro-pentofuranose was also achieved enzymically using e. coli, immobilised by ionotropic gelation in an alginate gel, with 2'-deoxyuridine as glycosyl donor. 5-amino-1-(2-deoxy-beta-d-erythro-pen ... | 1991 | 1797375 |
| synthesis of 4- and 5-amino-1-(2-deoxy-d-erythro-pentofuranosyl)imidazole nucleosides by chemical and biotransformation methods. | (2-deoxy-d-erythro-pentofuranosyl)imidazole nucleosides have been synthesised by glycosylation of the sodium salt of ethyl 5-aminoimidazole-4-carboxylate with 2-deoxy-3,5-di-o-p-toluoyl-alpha-d-erythro-pentofuranosyl chloride. glycosylation of ethyl 5-aminoimidazole-4-carboxylate with 2-deoxy-beta-d-erythro-pentofuranose was also achieved enzymically using e. coli, immobilised by ionotropic gelation in an alginate gel, with 2'-deoxyuridine as glycosyl donor. 5-amino-1-(2-deoxy-beta-d-erythro-pen ... | 1991 | 1797375 |
| synthesis of an artificial antigen that corresponds to a disaccharide repeating unit of the capsular polysaccharide of haemophilus influenzae type d. a facile synthesis of methyl 2-acetamido-2-deoxy-beta-d-mannopyranoside. | the synthesis is described of p-nitrophenyl 2-acetamido-3-o-(2-acetamido-2-deoxy-beta-d-glucopyranosyl)-2-deoxy-beta -d- mannopyranosiduronic acid, corresponding to the disaccharide repeating unit of the capsular polysaccharide of haemophilus influenzae type d, which, after conversion of the p-nitro- into a p-amino-phenyl residue, may be attached to a protein to make an artificial antigen for immunological studies. the synthesis incorporates a facile route to the 2-acetamido-2-deoxy-beta-d-manno ... | 1991 | 1797379 |
| structure of the o-specific polysaccharide chain from klebsiella pneumoniae o1k2 (nctc 5055) lipopolysaccharide. | the structure of the o-specific polysaccharide of klebsiella pneumoniae o1k2 lipopolysaccharide was investigated by use of methylation, periodate oxidation, partial hydrolysis, and 1h- and 13c-n.m.r. spectroscopy. it was shown to consist of a linear chain composed of two disaccharide repeating units, [----3)-alpha-d-galp-(1----3)-beta-d-galp-(1----] and [----3)-alpha-d-galp-(1----3)-beta-d-galf-(1----]. | 1991 | 1797395 |
| structure of the o-specific polysaccharide chain from klebsiella pneumoniae o1k2 (nctc 5055) lipopolysaccharide. | the structure of the o-specific polysaccharide of klebsiella pneumoniae o1k2 lipopolysaccharide was investigated by use of methylation, periodate oxidation, partial hydrolysis, and 1h- and 13c-n.m.r. spectroscopy. it was shown to consist of a linear chain composed of two disaccharide repeating units, [----3)-alpha-d-galp-(1----3)-beta-d-galp-(1----] and [----3)-alpha-d-galp-(1----3)-beta-d-galf-(1----]. | 1991 | 1797395 |
| in vitro activity of a new cephalosporin me-1206 compared with other agents. | the in vitro activity of me-1206, a new aminothiazolyl cephalosporin that can be orally absorbed when converted to an ester, was compared with that of other beta-lactams. me-1206 inhibited 50% of the enterobacteriaceae at 2 micrograms/ml, similar to cefotaxime, ceftazidime, and cefixime. it did not inhibit, mic greater than or equal to 32 micrograms/ml, enterobacter species or citrobacter freundii resistant to cefotaxime and ceftazidime, and it was less active than cefotaxime and ceftazidime aga ... | 1991 | 1797456 |
| in vitro activity evaluations of cefdinir (fk482, ci-983, and pd134393). a novel orally administered cephalosporin. | cefdinir, a so-called third-generation oral cephalosporin was tested in vitro against over 700 pathogens from patients with bacteremia. cefdinir was very active against the enterobacteriaceae with a 50% minimum inhibitory concentration (mic50) value range of less than or equal to 0.03-8 micrograms/ml. the enteric species having the highest mic90s (greater than or equal to 16 micrograms/ml) were citrobacter freundii, and the enterobacters, morganella morganii, proteus vulgaris, and serratia marce ... | 1991 | 1797457 |
| clinical & bacteriological profile of neonatal pneumonia. | in a prospective study of 44 neonates (33 outborn and 11 inborn) with pneumonia, the bacteriology of pneumonia was determined by blood culture and serum counterimmunoelectrophoresis (ciep). twenty-nine babies also underwent lung aspiration. the lung aspirate was subjected to bacterial culture and ciep. ciep was done to detect the bacterial antigens of streptococcus pneumoniae and haemophilus influenzae. absence of tachypnoea, found more commonly in low birth weight babies, was a poor prognostic ... | 1991 | 1797646 |
| [susceptibilities of clinical bacterial isolates to antimicrobial agents, 1989. a study mainly focused on imipenem. the research group for testing imipenem susceptibilities of clinical isolates]. | we investigated susceptibilities of clinical bacterial isolates to imipenem (ipm) and other antimicrobial agents at hospital laboratories throughout japan from september to december of 1989. the susceptibility testing was carried out according to the 1-dilution or 3-dilution disc technique in which susceptibilities are classified into 4 grades: (+++), (++), (+) and (-). ipm showed markedly high in vitro activities against streptococcus pneumoniae, neisseria gonorrhoeae, moraxella catarrhalis, es ... | 1991 | 1798067 |
| [rational bases of current etiopathogenetic therapy of bacterial meningitis. review of the literature and personal experience in 122 pediatric cases]. | bacterial meningitis is a serious infectious disease, the course of which depends on the correct use of antibiotics and an intensive symptomatic and support therapy. the presence of microbes and their fractions in the cns determines inflammatory phenomena that lead, through complex mechanisms, to the supportive treatment has the purpose of curbing the inflammatory phenomena, reducing cerebral oedema and avoiding ischaemia. this therapy makes use of cortisone and mannitol. the effectiveness of co ... | 1991 | 1798401 |
| dexamethasone in bacterial meningitis. | | 1991 | 1800325 |
| cefpodoxime: comparative antibacterial activity, influence of growth conditions, and bactericidal activity. | the antimicrobial activity of cefpodoxime, the active metabolite of the new cephalosporin ester cefpodoxime proxetil, in comparison to cefixime, cefotiam, cefuroxime, and cefotaxime was determined against a broad spectrum of freshly isolated gram-positive and gram-negative bacterial strains. cefpodoxime was demonstrated to be inhibitory at concentrations of less than or equal to 1 mg/l against 90% of strains of moraxella catarrhalis, haemophilus influenzae, escherichia coli (beta-lactamase- nega ... | 1991 | 1800379 |
| effects of prenatal antiandrogen treatment on masculinization and defeminization of guinea pigs. | gonadectomized (gdx) guinea pigs which had received the antiandrogen flutamide prenatally were tested for female-typical and male-typical sexual behavior in adulthood. in tests for lordosis behavior, gdx males and females were injected with estradiol benzoate and progesterone. prenatally flutamide-treated females showed a longer mean lordosis response than control females. this was true whether they were given either a high or a low dose of eb. no male ever showed a lordosis response. in tests f ... | 1991 | 1800997 |
| [the development of and experimentation with a kit for the identification and rapid biotyping of h. influenzae and h. parainfluenzae]. | the paper reports on the drawing up and experimentation of a kit of media for identification in liquid media and biotyping of h. influenza and h. parainfluenza. the kit is made up of 14 components, out of which the following were prepared: basic broth, x v broth, v broth, x broth, red-phenol broth, and xv factors + ribose, xylose and saccharose, urea substrate. moeller medium with xv, with and without ornithine, covered with paraffin oil after impregnation. in the xv broth and the broth with red ... | 1991 | 1802292 |
| [h. influenzae type c meningitis in an adult]. | the paper reports on the case of a 50-year-old patient with purulent meningitis caused by h. influenza type c, previously clinically healthy, without other associated disease. the disease had a mild evolution and the patient was cured after 7 days of etiologic and pathogenic treatment. the isolated strain was serotyped by the agglutination reactions on slides, coagglutination, counterimmunoelectrophoresis, and double immunodiffusion--being c serotype, and biotyped--being i serotype, sensitive to ... | 1991 | 1802293 |
| in vitro activity of ru29246. the metabolite of a new hr916 cephalosporin ester. | compound ru29246 (ru) is the active metabolite of an orally absorpted cephalosporin ester hr916. the ru spectrum of activity includes the majority of enterobacteriaceae species, haemophilus influenzae, pathogenic neisseria spp., moraxella catarrhalis, acinetobacter antiratus, staphylococci, and streptococcus spp. pseudomonas species and enterococci were routinely resistant to ru. the ru spectrum was most similar to cefixime against the gram-negative bacilli and to cefuroxime against the gram-pos ... | 1991 | 1802534 |
| quality control limits for disk diffusion and broth microdilution susceptibility tests with haemophilus test medium. | a six-center collaborative study was performed with the aim of developing quality control test limits for both disk diffusion and broth microdilution susceptibility tests with haemophilus influenzae atcc 49247 using haemophilus test medium. quality control ranges are presented for 18 antimicrobials: ampicillin, amoxicillin-clavulanate, ampicillin-sulbactam, cefuroxime, cefamandole, cefonicid, cefotaxime, ceftriaxone, ceftizoxime, ceftazidime, cefixime, chloramphenicol, tetracycline, trimethoprim ... | 1991 | 1802535 |
| pharmacological properties of cloned muscarinic receptors expressed in a9 l cells; comparison with in vitro models. | the effects of a series of muscarinic agonists and antagonists at cloned m1 and m3 muscarinic receptors expressed in mouse fibroblast a9 l cells have been compared with their effects in in vitro models of m1 (rat superior cervical ganglion) and m3 (guinea-pig ileum) muscarinic receptors. a good correlation existed between the potencies of muscarinic agonists at cloned m1 muscarinic receptors and the m1 sites in rat ganglion (r = 0.80) as well as at cloned m3 receptors and guinea-pig ileum m3 rec ... | 1991 | 1802743 |
| serum antibodies and bacterial meningitis. | the role of serum antibodies in bacterial meningitis and the human defence against it is reviewed. there is good evidence from animal and human studies in vitro and in vivo showing that serum antibodies to the capsular polysaccharide of the bacteria play a major role in protection, whereas antibodies to other cell surface components vary in protective ability. a major problem associated with the use of capsular polysaccharides as vaccines has been the t cell-independent nature of polysaccharide ... | 1991 | 1803693 |
| chemoprophylaxis of meningitis. | chemoprophylaxis of meningitis caused by neisseria meningitidis and haemophilus influenzae may be determined by the epidemiology of transmission, the antibiotic susceptibility patterns of the organisms, and the usage of vaccines. a review of transmission in england distinguishes differences in sporadic and cluster meningococcal infections. because of resistance to sulphadiazine, rifampicin and ciprofloxacin are prophylactic agents of choice. vaccination can be a useful adjunct to antibiotic prop ... | 1991 | 1803697 |
| antibiotic treatment of community acquired bacterial meningitis. | community acquired meningitis is predominantly caused by three agents: haemophilus influenzae, streptococcus pneumoniae and neisseria meningitidis four physical properties of available drugs--molecular size, protein binding, lipid solubility and ionization--affect drug entry to the central nervous system (cns). these factors, coupled with acute changes in blood-brain barriers and intrinsic bactericidal activity, have a bearing on the success of treatment with all agents. third generation cephalo ... | 1991 | 1803699 |
| interaction of imipenem with erythromycin and tetracycline assessed by microdilution checkerboard techniques. | microdilution methodology was used to study the interaction of imipenem with erythromycin and tetracycline, a combination therapy that might be used for the treatment of serious pelvic inflammatory disease. the combination of imipenem and erythromycin showed no antagonism for escherichia coli and haemophilus influenzae but was antagonistic for staphylococcus aureus, enterococcus faecalis, and group b streptococci; the combination of imipenem and tetracycline was antagonistic for all strains exce ... | 1991 | 1804015 |
| removal of the reca c-terminus results in a conformational change in the reca-dna filament. | the escherichia coli reca protein catalyzes homologous recombination of dna molecules, and the active form of the protein is a helical polymer that it forms around dna. previous image analysis of electron micrographs has revealed the reca protein to be organized into two domains or lobes within the reca-dna filament. we have now been able to show that a small modification of the reca protein by proteolysis results in a significant shift in the internal mass in the reca filament. we have cleaved ... | 1991 | 1804279 |
| immunoprophylaxis of otitis media. | prospects for an effective otitis media vaccine are bolstered by a number of encouraging observations. results of pneumococcal polysaccharide vaccine trials beginning in 1975, the enormously enhanced immunogenicity of protein-hib polysaccharide coupled vaccines in infants, and the apparent effectiveness of a protein-pcp coupled vaccine in experimental otitis media suggest that a pneumococcal vaccine targeted to prevent invasive and middle ear infections is not too distant. the identification of ... | 1991 | 1805562 |
| augmentation by interleukins of the antibody response to a conjugate vaccine against haemophilus influenzae b. | interleukins have been recognized as potential adjuvants for use during vaccination. the immunogenicity of some poorly immunogenic bacterial capsular polysaccharides have been improved by conjugation to a protein carrier. augmentation of the immune response to these glycoconjugates, however, may be realized in the presence of interleukins. the antibody response to one such vaccine which comprises a oligosaccharide derived from the capsule of haemophilus influenzae type b coupled to crm197 (hboc) ... | 1991 | 1805564 |
| an enzyme-linked immunosorbent assay for quantitation of haemophilus influenzae type b polysaccharide-specific igg1 and igg2 in human and infant rhesus monkey sera. | an enzyme-linked immunosorbent assay (elisa) has been developed and validated to quantitate igg1 and igg2 antibody to polyribosyl-ribitol phosphate (prp), the capsular polysaccharide of haemophilus influenzae type b (hib). the sera of children and infant rhesus monkeys immunized with an hib conjugate vaccine composed of hib prp covalently linked to an outer membrane protein complex (ompc) from neisseria meningitidis serogroup b (pedvaxhib, prp-ompc, merck, sharp and dohme research laboratories). ... | 1991 | 1806588 |
| [the olfactory orientation traits of white rats in a maze]. | some characteristics of olfactory behaviour of albino rats in three-arm maze have been studied. it was found that the olfactory discrimination of different food reinforcements may be elaborated in passages as long as 90 cm. choice reactions were determined by olfactory, not visual, stimuli on their simultaneous presentation. | 1991 | 1808972 |
| anti-adhesive molecules in human milk. | | 1991 | 1808992 |
| iga proteases of haemophilus influenzae dividing in human milk are inhibited by iga antibody in the milk. | | 1991 | 1809010 |
| steroid receptor assays: an italian quality assessment program. | an italian committee for the quality assessment of steroid receptor assay was instituted in 1979; the number of laboratories participating in this program increased from 7 in 1979 to 43 in 1989. the italian program in collaboration with eortc (european organization research and treatment of cancer) initiatives, utilizes as working standards lyophilized samples that tolerate prolonged storage at 4 degrees c. the national representatives agreed, according to eortc, that all laboratories would perf ... | 1991 | 1809075 |
| the promoter of dna puff gene ii/9-1 of sciara coprophila is inducible by ecdysone in late prepupal salivary glands of drosophila melanogaster. | dna puffs occur in sciarid salivary gland chromosomes; they are sites of dna amplification and intense transcription and they appear to encode secreted structural proteins needed for pupation. in this report we have used p-element transformation of drosophila to study regulation of a sciara dna puff gene. we found that a 718-bp promoter fragment of dna puff gene ii/9-1 from sciara coprophila directs expression of the bacterial reporter gene cat in late prepupal salivary glands of transgenic dros ... | 1991 | 1809395 |
| immunization: a 1991 update. part ii. | immunization is an important and changing area in pediatric practice. the school nurse plays a pivotal role in the ascertainment of appropriate immunization status for school children. the american academy of pediatrics committee on infectious disease has made a number of recent substantive changes in immunization requirements for both preschool and school-age children. this article will review the salient features of those changes, especially those related to school nursing practice. | 1991 | 1809465 |
| clinical results of a multicenter study with sulbactam/ampicillin for the treatment of patients with lower respiratory and urinary tract infections. | a total of 124 patients with lower respiratory tract (44) or urinary tract infections (80) were enrolled in an open, multicenter study to evaluate the efficacy and tolerability of sulbactam/ampicillin, administered at the dosage of 3 g/die by intramuscular route. pretreatment pathogens from patients with lower respiratory tract infections included: streptococcus alpha-haemolyticus in 8 cases, streptococcus beta-haemolyticus in 2 cases, staphylococcus albus in 7 cases, haemophilus influenzae in 7 ... | 1991 | 1809811 |
| vaccine-preventable respiratory infections in childhood. | in the past decade, immunization rates among preschool-age children in the united states have decreased to levels lower than those in many developing countries. as a result, epidemics of vaccine-preventable diseases have occurred, especially in urban areas. six of the infections prevented by immunization--those caused by bordetella pertussis, streptococcus pneumoniae, haemophilus influenzae type b, corynebacterium diphtheriae, measles virus, and influenza virus--frequently cause respiratory trac ... | 1991 | 1809999 |
| acute respiratory infections in children in the developing world. | the profound decline in death rates from respiratory infections in recent decades in the developed countries of the world is a complex phenomenon that probably results from a combination of socioeconomic and environmental change and modern medical care. death rates from respiratory infections in the developing world are very variable, and there is evidence that they can decrease dramatically when effective health services are engrafted onto a social environment in which mothers are literate and ... | 1991 | 1810000 |
| nontuberculous respiratory infections among the homeless. | in contrast to the extensive studies of pulmonary tuberculosis among homeless persons, virtually no data are available on nontuberculous respiratory infections in this population. this article reviews the literature on pulmonary infections and homelessness. the clinical experience of the boston health care for the homeless program is detailed, with emphasis on the role of multidisciplinary teams of physicians, nurses, and case workers in the integration of hospital- and shelter-based clinics nec ... | 1991 | 1810003 |
| adoptive transfer of activated human autologous macrophages results in regression of transplanted human melanoma cells in scid mice. | the potential anti-tumor activity of human macrophages, grown in macrophage colony stimulating factor (m-csf), was examined in mice homozygous for the mutation severe combined immune deficiency (scid) bearing xenografts of autologous human melanoma. injection of scid mice, bearing subcutaneous melanoma xenografts, with the cultured macrophages or with the macrophage culture supernatant, once or repeatedly, resulted in partial to complete regression of tumors. since a large number of such macroph ... | 1991 | 1810447 |
| immunogenicity and reactogenicity of haemophilus influenzae type b-meningococcus group b outer membrane protein conjugate vaccine in children 2-60 months of age. | haemophilus influenzae b - neisseria meningitidis group b outer membrane protein conjugate vaccine (hib-omp) was given to 571 children 2-60 months of age. two doses of hib-omp were given, 2 months apart, to 2-11 month old infants, and a single dose to children 12-60 month old. sera were obtained from a subset of vaccinees at each immunization, and at follow-up 1 month and 1 year after immunization. geometric mean antibody concentration (micrograms/ml) before and after full immunization were resp ... | 1991 | 1815340 |
| cerebrospinal fluid penetration of cefmenoxime in children with bacterial meningitis. | blood and cerebrospinal fluid (csf) concentrations of cefmenoxime were determined either microbiologically or by means of hplc in 20 children with proven or suspected bacterial meningitis. sixteen children suffered from bacterial meningitis: causative organisms were haemophilus influenzae type b (n = 10), streptococcus pneumoniae (n = 4) and neisseria meningitidis (n = 2). in these patients the cefmenoxime concentration in the csf ranged from 0.9 to 12.2 mg/l, with a mean concentration of 4.63 m ... | 1991 | 1816111 |
| phenotype versus genotype of the 19 kd peptido-glycan associated protein of legionella (ppia), among legionellae and other gram-negative bacteria. | the protein ppia (19 kd) cloned from a genomic library of legionella pneumophila, philadelphia 1, represents a peptido-glycan associated outer membrane protein in recombinant e. coli k-12 and l. pneumophila. it exhibits distinct sequence homology to lipoproteins of haemophilus influenzae and e. coli. a ppia specific dna probe generated by pcr was used in southern hybridizations of chromosomal dna of legionella strains and other gram-negative pathogens. under conditions of high stringency, hybrid ... | 1991 | 1816489 |
| aap updates hib vaccine recommendations. american academy of pediatrics. | | 1991 | 1816776 |
| the weight of the cortical inflow against medullary reflexes as enlightened by spectral analysis of hr and sp waves. | components of the autonomic drive to the heart were studied in 5 young normals subjected to: 1. sustained lung inflation (sli) in various postures; 2. mental loading by concentration of attention; 3. face immersion (fi) in cold water under sli or snorkel breathing, when sitting; 4. superpositions of 1-3 experimental interventions. recorded were: cardiotachogram (ctg as rr interval) and t-wave amplitude from ecg, ear-lobe photo-plethysmogram, digital impedance rheogram, thermistor pneumogram (png ... | 1991 | 1817664 |
| the weight of the cortical inflow against medullary reflexes as enlightened by spectral analysis of hr and sp waves. | components of the autonomic drive to the heart were studied in 5 young normals subjected to: 1. sustained lung inflation (sli) in various postures; 2. mental loading by concentration of attention; 3. face immersion (fi) in cold water under sli or snorkel breathing, when sitting; 4. superpositions of 1-3 experimental interventions. recorded were: cardiotachogram (ctg as rr interval) and t-wave amplitude from ecg, ear-lobe photo-plethysmogram, digital impedance rheogram, thermistor pneumogram (png ... | 1991 | 1817664 |
| thiourea and methionine effects upon glucose and leucine absorption in chicken jejunum. | administration of a unique dose of thiourea (7 mg per kg b.w.) in the 7th day of life to broiler chickens affects in different manners the jejunal absorption of glucose and that of leucine. methionine supplementation of the fodder (1.5 g per kg) during 40 days affects--in an age-dependent manner--the glucose absorption, but not that of leucine. | 1991 | 1817667 |
| thiourea and methionine effects upon glucose and leucine absorption in chicken jejunum. | administration of a unique dose of thiourea (7 mg per kg b.w.) in the 7th day of life to broiler chickens affects in different manners the jejunal absorption of glucose and that of leucine. methionine supplementation of the fodder (1.5 g per kg) during 40 days affects--in an age-dependent manner--the glucose absorption, but not that of leucine. | 1991 | 1817667 |
| antibacterial activities of amoxicillin alone and in combination with clavulanic acid correlated with beta-lactamase production. | amoxicillin, a beta-lactam antibiotic, was tested for its effect in combination with clavulanic acid, a beta-lactamase inhibitor, against 9 species of bacteria isolated from clinical specimens. a total of 698 strains of bacteria were tested for beta-lactamase production by the rapid chromogenic cephalosporin method. their susceptibilities to amoxicillin alone and in combination with clavulanic acid were tested by the agar dilution method. the percentage of beta-lactamase producing strains ranged ... | 1991 | 1818798 |
| [haemophilus vaccines. their importance in tropical pediatrics]. | immunization with haemophilus vaccine is undertaken to prevent invasive infections due to haemophilus influenzae type b. purulent meningitis is the most frequent chiefly in less than 2 years infants. vaccine is composed of purified prp which is poorly immunogenic and protective before two years. actual vaccines are conjugate with protein which give them a protective and immunogenic power in very long young infants. they must be included in the schedule of infants immunizations, and fitting to ot ... | 1991 | 1819437 |
| [epidemiological study of brazilian purpuric fever. epidemic in a locality of são paulo state (brazil), 1986]. | a case control model was used in the study of an outbreak of brazilian purpuric fever bpf which occurred in serrana, s. paulo state, brazil, in 1986. three hypotheses were raised: 1--purulent conjunctivitis is associated with bpf; 2--a cluster effect occurs in bpf; 3--respiratory symptoms may be a variation of the clinical picture of the disease. numerical values were attributed to different findings, as follows: fever = 5; diarrhea and/or vomiting = 1; haemorrhagic findings = 3; thrombocytopeni ... | 1991 | 1820627 |
| [chronic tonsillitis in childhood: a bacteriological study in connection with benzathine penicillin treatment and the role of bacterial flora in tonsillar hypertrophy]. | in this study the authors evaluated the importance of bacteriological study in the diagnostics of chronic tonsillitis in children and investigated the eventuality of modification in superficial as well as parenchymal tonsillar microflora brought about by preventive treatment with benzylpenicillin g. the study further aimed at revealing an eventual relationship between microflora and classic laboratory parameters (haemochromocytometric examination, leukocytic formula, ves, aslo and urine analysis ... | 1991 | 1820725 |
| [the effect of zinc on mineral, hematological and immunological indices in calves]. | the aim of this work was to study the effect of zinc added to feed on some selected biochemical and haematological indices and its stimulatory action on immunity of calves during its physiological decrease. investigations were carried out on 18 calves aged 20 days. twelve calves were divided into 2 groups and they received 450 and 900 mg of zn++ under the form of znso4 x 7h2o. the following parameters were examined: serum and tissue concentrations of zn, cu, fe and ca, number of erythrocytes and ... | 1991 | 1821031 |
| [haemophilus influenzae and genital infection]. | we report nine cases of h. influenzae genital infections in women. six patients had a total of 7 episodes of bartholin glands abscess. one patient developed a post-caesarean endomyometritis on the 16th post-delivery day. the remaining patient developed an amniotic fluid infection in the 32nd week of pregnancy. all the nine h. influenzae strains were sensitive to ampicillin. we assess the rising importance of h. influenzae as an etiologic agent of female genital tract infections. | 1991 | 1822153 |
| blood-brain barrier alterations in bacterial meningitis: development of an in vitro model and observations on the effects of lipopolysaccharide. | to further examine the effects of purified haemophilus influenzae type b lipopolysaccharide (lps) on blood-brain barrier permeability, we have developed an in vitro model of the bbb. microvascular endothelial cells were isolated from rat cerebral cortices by enzymatic digestion, dextran centrifugation, and separation on percoll gradients. the cells were determined to be endothelial in origin by positive fluorescent staining for factor viii-related antigen and the ability to take up acetylated lo ... | 1991 | 1826902 |
| the development of macrolides: clarithromycin in perspective. | macrolide antibiotics have been available and used clinically since 1952. the class of drugs originated from a soil sample obtained from the city of ilo-ilo on the island of paray in the philippines. erythromycin has been the most widely used agent of this class called 'macrolides' because they possess the macrocyclic lactone nucleus. many esters of erythromycin are well established as agents to treat a variety of respiratory and cutaneous infections, particularly in children. there has been a r ... | 1991 | 1827094 |
| comparative study of clarithromycin and roxithromycin in the treatment of community-acquired pneumonia. | the efficacy and tolerance of clarithromycin (250 mg twice daily) were compared with those of roxithromycin (150 mg twice daily) in an open, multicentre trial of 77 inpatients with community-acquired pneumonia. sixty-five patients were clinically evaluable (34, clarithromycin; 31 roxithromycin). efficacy was comparable between treatment groups: 26 of 34 patients (76%) treated with clarithromycin were clinically cured, including four with atypical pneumonia. in the roxithromycin group 25 of 31 pa ... | 1991 | 1827096 |
| in-vitro activity of clarithromycin combined with its 14-hydroxy metabolite a-62671 against haemophilus influenzae. | clarithromycin and its 14-hydroxy metabolite (a-62671), were tested against 20 strains of haemophilus influenzae. minimum inhibitory and bactericidal concentrations of the two compounds alone and in combination were determined in a microbroth system which allowed continuous turbidimetric measurement for the construction of growth curves. mics of clarithromycin were 2-8 and 1-4 mg/l for a-62671 for the majority of strains. mbcs were identical to or one dilution higher than the respective mics. co ... | 1991 | 1827097 |
| the activity of clarithromycin and its 14-hydroxy metabolite against haemophilus influenzae, determined by in-vitro and serum bactericidal tests. | the in-vitro activity of clarithromycin and its main metabolite 14-hydroxy clarithromycin against haemophilus influenzae was evaluated by determining minimum inhibitory and minimum bactericidal concentrations. the 14-hydroxy metabolite was more active than the parent compound against h. influenzae. the activity of the parent compound/metabolite combination was evaluated against 20 strains of h. influenzae by the chequerboard technique. the combination was synergistic against seven isolates in te ... | 1991 | 1827099 |
| individual and combined activities of clarithromycin and its 14-hydroxy metabolite in a murine model of haemophilus influenzae infection. | clarithromycin is metabolised in man mainly to the 14-hydroxy derivative, which is also biologically active. as this metabolite is not produced in rodents, we used a murine model of haemophilus influenzae pulmonary infection to compare the in-vivo activity of clarithromycin and 14-hydroxy clarithromycin, alone and in combination, and erythromycin. in terms of bacterial killing, clarithromycin's 14-hydroxy metabolite was much more active than clarithromycin and erythromycin at doses of 100 mg/kg. ... | 1991 | 1827100 |
| [pharmacokinetic and clinical studies of cefpirome in pediatric field]. | we conducted a study on the pharmacokinetics and clinical application of cefpirome (cpr) in children. 1. a single intravenous injection of 20 mg/kg of cpr was given to a two-month-old boy, and the concentration of the drug in the blood was measured. fifteen minutes after administration, the concentration was 53.3 micrograms/ml, and it gradually decreased thereafter, reaching a level of 5.18 micrograms/ml after 8 hours with a half-life in the plasma of 2.36 hours. 2. a single intravenous injectio ... | 1991 | 1828275 |
| inhibitory effect of inhaled procaterol on anaphylactic bronchoconstriction and thromboxane a2 production in guinea-pigs. | this study was designed to examine whether an inhaled beta 2-agonist, procaterol, inhibits thromboxane a2 (txa2) production induced by antigen challenge in passively sensitized guinea-pigs in vivo. antigen-induced bronchoconstriction was markedly inhibited by pre-treatment with procaterol. inhaled procaterol significantly reduced in a dose-dependent manner the increment in txb2 concentration in bronchoalveolar lavage fluid obtained 5 min after antigen challenge. aerosol administration of procate ... | 1991 | 1828386 |
| inhibitory effect of inhaled procaterol on anaphylactic bronchoconstriction and thromboxane a2 production in guinea-pigs. | this study was designed to examine whether an inhaled beta 2-agonist, procaterol, inhibits thromboxane a2 (txa2) production induced by antigen challenge in passively sensitized guinea-pigs in vivo. antigen-induced bronchoconstriction was markedly inhibited by pre-treatment with procaterol. inhaled procaterol significantly reduced in a dose-dependent manner the increment in txb2 concentration in bronchoalveolar lavage fluid obtained 5 min after antigen challenge. aerosol administration of procate ... | 1991 | 1828386 |
| antidepressant-like effects of buspirone mediated by the 5-ht1a post-synaptic receptors in the learned helplessness paradigm. | the 5-ht1a receptor agonists buspirone and 8-oh-dpat have strong effects on serotoninergic systems. mediated by both pre- and post-synaptic 5-ht1a receptors, these pharmacological effects might predict both antidepressant and antianxiety activities. in animal models sensitive to antidepressant drugs, the 5-ht1a agonists administered i.p. have been shown to mimic the behavioral effects of tricyclics. in the present study, the learned helplessness paradigm was used to assess the possible role of p ... | 1991 | 1828519 |
| antidepressant-like effects of buspirone mediated by the 5-ht1a post-synaptic receptors in the learned helplessness paradigm. | the 5-ht1a receptor agonists buspirone and 8-oh-dpat have strong effects on serotoninergic systems. mediated by both pre- and post-synaptic 5-ht1a receptors, these pharmacological effects might predict both antidepressant and antianxiety activities. in animal models sensitive to antidepressant drugs, the 5-ht1a agonists administered i.p. have been shown to mimic the behavioral effects of tricyclics. in the present study, the learned helplessness paradigm was used to assess the possible role of p ... | 1991 | 1828519 |
| effect of subcutaneous and intraperitoneal administration of recombinant human erythropoietin on blood pressure and vasoactive hormones in patients on continuous ambulatory peritoneal dialysis. | the effect of subcutaneous and intraperitoneal administration of recombinant human erythropoietin (rhuepo) on blood pressure was evaluated in 20 patients with renal failure on continuous ambulatory peritoneal dialysis. the two groups of patients were commenced on a 16-week course of twice weekly rhuepo by either the subcutaneous (10 patients) or the intraperitoneal route (10 patients). one patient in the latter group was subsequently excluded because of operation and transfusion. the hemoglobuli ... | 1991 | 1828543 |
| effect of subcutaneous and intraperitoneal administration of recombinant human erythropoietin on blood pressure and vasoactive hormones in patients on continuous ambulatory peritoneal dialysis. | the effect of subcutaneous and intraperitoneal administration of recombinant human erythropoietin (rhuepo) on blood pressure was evaluated in 20 patients with renal failure on continuous ambulatory peritoneal dialysis. the two groups of patients were commenced on a 16-week course of twice weekly rhuepo by either the subcutaneous (10 patients) or the intraperitoneal route (10 patients). one patient in the latter group was subsequently excluded because of operation and transfusion. the hemoglobuli ... | 1991 | 1828543 |
| [recurrent bivalvular endocarditis caused by haemophilus influenzae]. | | 1991 | 1828586 |
| studies on lipid peroxidation in rat tissues following administration of low and moderate doses of cadmium chloride. | the susceptibility to lipid peroxidation (lpo) of liver, kidneys, brains, lungs, heart, and testes was assessed in rats administered intraperitoneally with various doses of cadmium (cd). dose-response studies were carried out with male long evans rats (12-week-old; 300 +/- 33 g) injected with 25, 125, 500, and 1250 micrograms cd/kg as cdcl2 and sacrificed after 24 h. in time-response studies, animals were administered with 25 and 500 micrograms cd/kg as cdcl2 and sacrificed after 2, 6, 12, 24, a ... | 1991 | 1828634 |
| studies on lipid peroxidation in rat tissues following administration of low and moderate doses of cadmium chloride. | the susceptibility to lipid peroxidation (lpo) of liver, kidneys, brains, lungs, heart, and testes was assessed in rats administered intraperitoneally with various doses of cadmium (cd). dose-response studies were carried out with male long evans rats (12-week-old; 300 +/- 33 g) injected with 25, 125, 500, and 1250 micrograms cd/kg as cdcl2 and sacrificed after 24 h. in time-response studies, animals were administered with 25 and 500 micrograms cd/kg as cdcl2 and sacrificed after 2, 6, 12, 24, a ... | 1991 | 1828634 |
| development of in-vitro resistance to glycopeptide antibiotics: assessment in staphylococci of different species. | forty-two clinical isolates belonging to ten species of staphylococci were studied for their ability to develop single-step resistance, in vitro, to glycopeptide antibiotics. selection was attempted through separate exposure to four glycopeptides (vancomycin, teicoplanin, and two investigational semisynthetic derivatives of the latter, td-a3 and cta-a1) on agar containing 10 mg/l of the test drug. no survivors from any test strain were recovered after exposure to td-a3 or cta-a1. after exposure ... | 1991 | 1828799 |
| reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (gm-csf): evidence that the protein encoded by the aic2b cdna is a subunit of the murine gm-csf receptor. | the high-affinity receptor for human granulocyte/macrophage colony-stimulating factor (hgm-csf) is composed of two subunits, alpha and beta. the alpha subunit binds gm-csf with low affinity, whereas the beta subunit does not bind gm-csf by itself. the alpha and beta subunits together form the high-affinity gm-csf receptor. the beta subunit has extensive sequence homology with the mouse interleukin 3 (il-3) receptor (aic2a) and its homologue (aic2b) that does not bind il-3 or other cytokines incl ... | 1991 | 1828890 |
| paired tumour infiltrating lymphocyte (til) and tumour cell line from bladder cancer: a new approach to study tumour immunology in vitro. | this paper reports the first example of tumour infiltrating lymphocytes (tils) and a tumour cell line from the same individual and analyses their characteristics. the tumour cell line (cat), derived from a patient with well-differentiated (g3pta) tcc, has been in culture for 24 months and subcultured more than 100 times. epithelial origin was established by electronmicroscopy and use of a range of monoclonal antibodies (mabs) against cytokeratins. the tils isolated from the same tumour expressed ... | 1991 | 1828972 |
| paired tumour infiltrating lymphocyte (til) and tumour cell line from bladder cancer: a new approach to study tumour immunology in vitro. | this paper reports the first example of tumour infiltrating lymphocytes (tils) and a tumour cell line from the same individual and analyses their characteristics. the tumour cell line (cat), derived from a patient with well-differentiated (g3pta) tcc, has been in culture for 24 months and subcultured more than 100 times. epithelial origin was established by electronmicroscopy and use of a range of monoclonal antibodies (mabs) against cytokeratins. the tils isolated from the same tumour expressed ... | 1991 | 1828972 |
| nitrosoureas lomustine, carmustine and fotemustine induced hepatotoxic perturbations in rats: biochemical, morphological and flow cytometry studies. | chloroethylnitrosoureas are reactive compounds that are highly effective against malignant neoplasms in humans and animals. the most widely used nitrosoureas, lomustine and carmustine, are known to be hepatotoxic and to induce pericholangitis and intrahepatic cholestasis, which in the long term lead to cholangiolysis and biliary cirrhosis. however, the nitrosourea fotemustine has proved to be non-hepatotoxic at 20 mg/kg and 50 mg/kg. we have studied the effect of these three nitrosoureas on the ... | 1991 | 1828975 |
| nitrosoureas lomustine, carmustine and fotemustine induced hepatotoxic perturbations in rats: biochemical, morphological and flow cytometry studies. | chloroethylnitrosoureas are reactive compounds that are highly effective against malignant neoplasms in humans and animals. the most widely used nitrosoureas, lomustine and carmustine, are known to be hepatotoxic and to induce pericholangitis and intrahepatic cholestasis, which in the long term lead to cholangiolysis and biliary cirrhosis. however, the nitrosourea fotemustine has proved to be non-hepatotoxic at 20 mg/kg and 50 mg/kg. we have studied the effect of these three nitrosoureas on the ... | 1991 | 1828975 |
| in vitro folding pathway of phage p22 tailspike protein. | the intracellular chain folding and association pathway of the thermostable, trimeric phage p22 tailspike endorhamnosidase has been the subject of a previous detailed study employing temperature-sensitive folding mutants. recently, reconstitution of native tailspikes from completely unfolded polypeptides has been accomplished, providing a model system to compare protein folding pathways in vivo and in vitro. the in vitro reconstitution pathway of the protein after dilution from guanidine hydroch ... | 1991 | 1828991 |
| in vitro folding pathway of phage p22 tailspike protein. | the intracellular chain folding and association pathway of the thermostable, trimeric phage p22 tailspike endorhamnosidase has been the subject of a previous detailed study employing temperature-sensitive folding mutants. recently, reconstitution of native tailspikes from completely unfolded polypeptides has been accomplished, providing a model system to compare protein folding pathways in vivo and in vitro. the in vitro reconstitution pathway of the protein after dilution from guanidine hydroch ... | 1991 | 1828991 |
| the in-vitro and disc susceptibility testing of clarithromycin and its 14-hydroxy metabolite. | the in-vitro antibacterial activity of clarithromycin, its 14-hydroxy metabolite and a combination containing clarithromycin and the 14-hydroxy metabolite in a ratio of three parts of the former to one part of the latter were compared with erythromycin by determination of mics. disc susceptibility testing was also performed using discs containing 6 micrograms clarithromycin, 6 micrograms clarithromycin with 2 micrograms 14-hydroxy-clarithromycin, 3 micrograms clarithromycin and 3 micrograms clar ... | 1991 | 1829073 |
| [mechanism of parathyroid cell proliferation in primary hyperparathyroidism]. | in primary hyperparathyroidism molecular biology techniques applied to the pathological parathyroid tissue have shown that cell proliferation is monoclonal in many sporadic adenomas and in the largest parathyroid glands of multiple endocrine neoplasia type 1 (men-1). on the other hand, monoclonality has not been found in sporadic hyperplasia and in the smaller parathyroid glands of men-1. in addition, abnormalities have been observed in chromosome 11 which contains the parathyroid hormone (pth) ... | 1991 | 1829167 |
| [search for correlation between lowered folate and increased neopterin serum levels in hiv infected patients]. | | 1991 | 1829181 |
| [role of giardiasis in non-ulcer dyspepsia]. | in 1987 and 1988, 340 consecutive patients attended the endoscopy centre of cochin hospital, paris, and underwent oesophago-gastroduodenal endoscopy in a search for giardia lamblia parasitology and histology. two-hundred and eight of these patients presented with non-ulcer dyspepsia and entered a prospective study aimed at determining the advisability of a systematic search for giardia lamblia in this population. six biopsies were positive for giardiasis, including 3 in patients with acquired im ... | 1991 | 1829198 |
| [mean values of risk factors for ischemic heart disease and their percentile distributions in the alma-ata population of men aged 20-54]. | the authors analyze the results of a one-stage epidemiological study of the open population of men aged 20-54 years (n-2886), carried out with a purpose of revealing coronary heart disease (chd) and its risk factors (rf). the study was performed with the aid of the standard who methods of epidemiological investigations. the prevalence of the main chd rf (arterial and borderline hypertension, overweight, tobacco-smoking, dyslipoproteinemias) was established. the mean values of rf in different age ... | 1991 | 1829274 |
| peritoneal macrophage response: an in vivo model for the study of synthetic materials. | this study was designed to validate an in vivo model in rat to study cell-implant interactions. pieces of dacron and goretex and polydimethylsiloxane (reference material) precoated or not were implanted in the peritoneal cavity. in some cases the peritoneal cells were stimulated before the implantation. macrophage phagocytosis and fibrinocoagulolytic activities were investigated in parallel with morphological studies 6 h after implantation. a graded cell response related to the different situati ... | 1991 | 1831674 |
| peritoneal macrophage response: an in vivo model for the study of synthetic materials. | this study was designed to validate an in vivo model in rat to study cell-implant interactions. pieces of dacron and goretex and polydimethylsiloxane (reference material) precoated or not were implanted in the peritoneal cavity. in some cases the peritoneal cells were stimulated before the implantation. macrophage phagocytosis and fibrinocoagulolytic activities were investigated in parallel with morphological studies 6 h after implantation. a graded cell response related to the different situati ... | 1991 | 1831674 |
| activation of the plasma membrane h(+)-atpase of saccharomyces cerevisiae by addition of hydrogen peroxide. | addition of hydrogen peroxide (greater than 10 mm) to aerated derepressed cells of s. cerevisiae in the absence of substrate caused a boost of endogenous respiration and both intra- and extracellular acidification, without any significant change in cellular atp level. furthermore, a hyperpolarization of the plasma membrane was indicated by an enhanced accumulation of tetraphenylphosphonium in the cells. the extracellular ph attained was as low as 3.5. the acidification could be suspended by the ... | 1991 | 1831983 |
| in-vitro cidal activity of clarithromycin and its 14-hydroxy metabolite (a-62671) against haemophilus influenzae. | | 1991 | 1832146 |
| current status of pediatric vaccines. | pediatric immunization schedules have become more complex, especially with the approval of two new vaccines for haemophilus influenzae type b and changes in recommendations for measles vaccine. in addition, vaccines for other infections (eg, rotavirus, varicella, and respiratory syncytial virus) are in development and likely will become available in the future. these recent advances raise hope that the list of diseases eradicated through vaccination will be expanded. | 1991 | 1833727 |
| activity of clarithromycin and its principal human metabolite against haemophilus influenzae. | clarithromycin is a new macrolide antibiotic which forms a microbiologically active principal in vivo metabolite, 14-oh-clarithromycin. the in vitro activities of clarithromycin and its metabolite were examined separately and in pharmacokinetically relevant fixed combinations of 4:1 and 2:1 against a group of 50 haemophilus influenzae isolates. broth microdilution susceptibility tests indicated that clarithromycin was less active than erythromycin against all but highly erythromycin-susceptible ... | 1991 | 1834012 |
| bactericidal activity of clarithromycin and its 14-hydroxy metabolite against haemophilus influenzae and streptococcal pathogens. | the serum bactericidal activity of clarithromycin in six normal human volunteers was determined after oral doses of 500 mg. the mean plasma levels of clarithromycin plus 14-hydroxy clarithromycin were 2.11 micrograms/ml after the second dose and 4.36 micrograms/ml after the sixth dose. the mean serum bactericidal titer against haemophilus influenzae after the second dose was 1:8 and after the sixth dose 1:16 when unheated serum was used. similar values were obtained when serum to which clarithro ... | 1991 | 1837032 |
| [antigens for the diagnosis of tick-borne encephalitis using the elisa technique]. | from the brains of suckling mice infected with the virus of tickborne encephalitis, strain hypr, the authors concentrated by precipitation with polyethylene glycol - 6000 and purified by differential ultracentrifuging on a linear saccharose gradient the virion antigen kev-ii for assessment of specific human antibodies, using the indirect elisa technique. the antigen was characterized as to haemagglutination activity, electrophoretic properties, immunoblotting with a monoclonal antibody against e ... | 1991 | 1838712 |
| esgab breakpoint determination: clarithromycin. | | 1991 | 1838979 |
| [effect of anp on estradiol and progesterone production by rat ovarian cells]. | isolated ovarian corpus luteal cells and granulosa cells of rat were employed to investigate the effect of alpha-anp on the secretion of progesterone and estradiol. the contents of the steroid hormones are determined by ria. the results showed that 0.1-10 ng/ml anp promoted progesterone production in a dose dependent manner. alpha-anp also enhanced progesterone production by granulosa cells, but not estradiol. it seems that the effect of alpha-anp on ovarian steroidogenesis is a direct one. | 1991 | 1839085 |
| susceptibility of haemophilus influenzae to clarithromycin alone and in combination with its 14-hydroxy metabolite. | | 1991 | 1839381 |
| in-vitro antimicrobial susceptibility of australian isolates of treponema hyodysenteriae. | | 1991 | 1839652 |
| [etiology, clinical course, and the methods and results of the treatment of suppurative meningoencephalitis in adults--personal observations data]. | the authors discuss problems connected with the clinical, aetiological diagnosis, methods and results of treatment of purulent meningoencephalitis in adults. the basis for the discussion were own experiences obtained during hospitalization of 578 patients in the period 1981-1990. as a results of this analysis the authors found that the organisms causing this disease most frequently were, as previously, neisseria meningitidis and anaerobic haemophilus influenzae were still highly unsatisfactory. ... | 1991 | 1841420 |