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the neisseria meningitidis znud zinc receptor contributes to interactions with epithelial cells and supports heme utilization when expressed in escherichia coli.neisseria meningitidis employs redundant heme acquisition mechanisms, including tonb receptor-dependent and receptor-independent uptakes. the tonb-dependent zinc receptor znud shares significant sequence similarity to huma, a heme receptor of moraxella catarrhalis, and contains conserved motifs found in many heme utilization proteins. we present data showing that, when expressed in escherichia coli, znud allowed heme capture on the cell surface and supported the heme-dependent growth of an e. co ...201122083713
Effect of nasal mometasone furoate on the nasal and nasopharyngeal flora.OBJECTIVE: Mometasone furoate (MF) is one of the commonly used topical steroids, particularly for patients with allergic rhinitis. However, its effect on the colonization of bacteria that may cause superinfections by suppressing the local immunity is not known. Thus, we investigated the effect of MF use on the nasal and nasopharyngeal microbial flora. MATERIALS AND METHODS: Swab samples were taken from 35 patients who required MF monotherapy, just before and after one month of the treatment. Sam ...201121889281
Quantification of polyphenols during retting and characterization of bacteria from the Kadinamkulam Backwaters, Kerala.The retting environment which provides a competitive niche for specialized microbes is speculated to harbour a variety of microbes with high biodegradation potential. In this context, an effort has been made to isolate and identify bacterial species having high tolerance to phenol In vitro. Maximum polyphenol (1.897 mg l(-1)) as observed during the initial period of retting, which decreased as retting proceeded. Based on biochemical characterization, the isolated bacterial strains were identifie ...201121888245
moraxella catarrhalis as a respiratory pathogen.background: moraxella catarrhalis is gaining significance as a pathogen over few decades because of increased rate of isolation in respiratory specimens and due to emergence of multidrug resistant strains. therefore, appropriate antimicrobial agents are required for eradication and prevention of spread of the organism. material and methods: -the study was conducted over 1-year period inpatients of lower respiratory tract infections (l.r.t.i.) in p.g.i.m.s. rohtak (haryana) . assessment of clinic ...201122234107
bronchoscopic findings in children with chronic wet cough.objectives:protracted bacterial bronchitis is defined as the presence of more than 4 weeks of chronic wet cough that resolves with appropriate antibiotic therapy, in the absence of alternative diagnoses. the diagnosis of protracted bacterial bronchitis is not readily accepted within the pediatric community, however, and data on the incidence of bacterial bronchitis in children are deficient. the objective of this study was to determine the frequency of bacterial bronchitis in children with chron ...201222232311
first case report of moraxella osloensis diarrhea in a hemolytic uremic syndrome/acute renal failure child from rural coastal india-manipal, karnataka.the authors report a rare case of diarrhea caused by moraxella osloensis in a pediatric child with hemolytic uremic syndrome/acute renal failure (hus/arf). a 6-y-old boy was referred to the pediatric unit with a 3 d history of bloody diarrhea with mucus and fever and decreased urine output for 6 d. microbiological investigations were done as per clsi guidelines. his diarrhea, and the subsequent renal failure resolved with appropriate treatment. to the best of authors' knowledge and pubmed search ...201222231773
evaluation of cytokines as adjuvants of infectious bovine keratoconjunctivitis vaccines.in this work two cytokines were used in combination with inactivated bacteria (bacterin) to test the bovine conjuctival immune response to the pathogen moraxella bovis, the causative agent of infectious bovine keratoconjunctivitis (ibk). treatments using the bacterin vaccine combined with interleukin-2 and interferon-α as adjuvants (group a), the bacterin vaccine only (group b), and controls without treatment (group c), were applied by ocular spraying to evaluate the local immune response in the ...201222264735
intranasal immunization of the combined lipooligosaccharide conjugates protects mice from the challenges with three serotypes of moraxella catarrhalis.there are no licensed vaccines available against moraxella catarrhalis, a significant human respiratory pathogen. lipooligosaccharide (los) based conjugate vaccines derived from individual serotype m. catarrhalis only showed partial protection coverage. a vaccine combining los conjugates of two or three serotypes might provide a broader protection.201122216312
23-gauge transconjunctival sutureless vitrectomy in treatment of post-operative endophthalmitis.purpose: to report the safety and efficacy of 23-gauge (23-g) transconjunctival vitrectomy (tsv) in the surgical management of postoperative endophthalmitis. materials and methods: ten consecutive patients underwent a 23-g tsv in 2008-2010 after cataract surgery (n = 5) or filtrating surgery (n = 5), and were prospectively studied with a minimum follow-up of 6 months. tsv was performed within a median delay of 1  ...201222270218
microbiology of acute and chronic maxillary sinusitis in smokers and nonsmokers.we evaluated the microbiology of sinus aspirates of smokers and nonsmokers with acute and chronic maxillary sinusitis.201122224311
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