| molecular epidemiology of adenovirus type 7 in the united states, 1966-2000. | genetic variation among 166 isolates of human adenovirus 7 (ad7) obtained from 1966 to 2000 from the united states and eastern ontario, canada, was determined by genome restriction analysis. most (65%) isolates were identified as ad7b. two genome types previously undocumented in north america were also identified: ad7d2 (28%), which first appeared in 1993 and was later identified throughout the midwest and northeast of the united states and in canada; and ad7h (2%), which was identified only in ... | 2002 | 11927024 |
| infectious etiologies of transient neutropenia in previously healthy children. | healthy children presenting with neutropenia are often hospitalized and treated empirically with antibiotics without an evidence of infection. the objective of this study was to investigate the infectious causes of isolated transient neutropenia in otherwise previously healthy children. | 2012 | 22414904 |
| bacterial and viral pathogen spectra of acute respiratory infections in under-5 children in hospital settings in dhaka city. | the study aimed to examine for the first time the spectra of viral and bacterial pathogens along with the antibiotic susceptibility of the isolated bacteria in under-5 children with acute respiratory infections (aris) in hospital settings of dhaka, bangladesh. nasal swabs were collected from 200 under-five children hospitalized with clinical signs of aris. nasal swabs from 30 asymptomatic children were also collected. screening of viral pathogens targeted ten respiratory viruses using rt-qpcr. b ... | 2017 | 28346512 |
| adenovirus type 7 associated with severe and fatal acute lower respiratory infections in argentine children. | adenoviruses are the second most prevalent cause of acute lower respiratory infection of viral origin in children under four years of age in buenos aires, argentina. the purpose of this study was to analyze the clinical features and outcome of acute lower respiratory infection associated with different adenovirus genotypes in children. | 2002 | 12184818 |
| [cloning and sequencing of adenovirus type 7 vaccine strain 76.5-87 mu fragment]. | adenovirus 7(ad7) vaccine strain has been used more than 30 years in us army recruits for prevention of ad7 infection and has been proven to be safe and effective. recent years more attention has been paid to exploring the possibilities of using it for gene therapy or making recombinant vaccine. in order to construct adenovirus 7 vector, ad 7 vaccine strain 76.5-87 mu fragment was cloned and sequenced. the fragment contains 3,557 bp which encodes 6 proteins of e3 region, namely 12.1 kd, 19.2 kd, ... | 1998 | 12526316 |
| an outbreak of acute respiratory disease caused by a virus associated rna ii gene mutation strain of human adenovirus 7 in china, 2015. | human adenovirus 7 (hadv-7) strains are a major cause of acute respiratory disease (ard) among adults and children, associated with fatal pneumonia. an ard outbreak caused by hadv-7 that involved 739 college students was reported in this article. to better understand the underlying cause of this large-scale epidemic, virus strains were isolated from infected patients and sequence variations of the whole genome sequence were detected. evolutionary trees and alignment results indicated that the ma ... | 2017 | 28225804 |
| complete genome sequence of human adenovirus 7 associated with fatal adult pneumonia. | human adenovirus 7 (hadv7) 19bovlb/volgograd/rus/2014 was isolated from the autopsy material from an adult with fatal pneumonia in volgograd, russia, in march 2014. whole-genome sequencing of the virus isolate was performed. | 2016 | 27789645 |
| severe pneumonia caused by adenovirus 7 in pregnant woman: case report and review of the literature. | we report a rare case of adenoviral pneumonia in a previously healthy pregnant woman at 26(+4) weeks' gestation. she presented with persistent high fever, cough for 5 days, and developed progressive dyspnea with hypoxemic respiratory failure and bilateral pulmonary infiltrates with pleural effusions. aggressive supportive care and timely obstetrical management saved the mother and prevented preterm delivery and fetal anomaly. | 2016 | 27325617 |
| human adenovirus associated with severe respiratory infection, oregon, usa, 2013-2014. | several human adenoviruses (hadvs) can cause respiratory infections, some severe. hadv-b7, which can cause severe respiratory disease, has not been recently reported in the united states but is reemerging in asia. during october 2013-july 2014, oregon health authorities identified 198 persons with respiratory symptoms and an hadv-positive respiratory tract specimen. among 136 (69%) hospitalized persons, 31% were admitted to the intensive care unit and 18% required mechanical ventilation; 5 patie ... | 2016 | 27191834 |
| evaluation of epidemiological and clinical features of influenza and other respiratory viruses. | in our study, we aimed to clinically and epidemiologically evaluate respiratory tract infections the viral agents of which were detected by molecular methods and to compare influenza and other respiratory tract viruses in this context. | 2015 | 26884691 |
| [construction of adenovirus type 7(vaccine strain) vector and expression of beta-galactosidase gene]. | human adenovirus type 7 dna was extracted from purified virus cultured in wi-38 cells. the essential fragment (68-100 mu) of ad7 dna was used for constructing a non-defective ad7 vector termed as pad7 delta e3. the vector was characterized by a deletion at the e3 region that contains a multicloning site for the insertion of foreign genes. a helper-independent adenovirus type 7-beta-galactosidase recombinant was established. the recombinant contains the beta-galactosidase gene flanked by cmv earl ... | 1998 | 12526338 |
| adenovirus meningoencephalitis in a patient with large b-cell lymphoma. | we report a case of a 58-year-old female with neuromeningeal relapse of a large b-cell lymphoma which developed a meningoencephalitis due to adenovirus (adv). diagnosis of suspected viral meningoencephalitis was based on computed tomography (ct) scan radiological pictures, which were atypical for cns neoplastic infiltrations, and it was confirmed by direct immunofluorescence performed on cerebrospinal fluid. cultural exams identified adenovirus type 7. the adv infection resolved after treatment ... | 2003 | 12679888 |
| significant transplantation-related mortality from respiratory virus infections within the first one hundred days in children after hematopoietic stem cell transplantation. | respiratory viral infections (rvi) are important in hematopoietic stem cell transplantations (hsct) and knowledge regarding incidence, morbidity, mortality, and long-term pulmonary complications is limited. we report a study to evaluate incidence and outcomes, both short and long-term, of rvi in children receiving hsct. between january 2000 and december 2012, 844 patients underwent hematopoietic stem cell transplantation (hsct) at the hospital for sick children: 491 were allogeneic and 353 were ... | 2015 | 26117558 |
| prevalence of respiratory virus in symptomatic children in private physician office settings in five communities of the state of veracruz, mexico. | acute respiratory tract infections are the leading cause of morbidity and mortality in children worldwide. many studies have described the frequency of viruses in hospitalized patients, but studies describing the prevalence of viruses in the community setting are limited, particularly in developing countries, where most of the deaths from serious respiratory diseases occur. the aim of this study was to evaluate the diversity of respiratory viruses in the community setting using molecular diagnos ... | 2015 | 26108920 |
| severe pediatric adenovirus 7 disease in singapore linked to recent outbreaks across asia. | during november 2012-july 2013, a marked increase of adenovirus type 7 (ad7) infections associated with severe disease was documented among pediatric patients in singapore. phylogenetic analysis revealed close genetic links with severe ad7 outbreaks in china, taiwan, and other parts of asia. | 2015 | 26079293 |
| infections with adenovirus type 7 in children and their relationship to acute respiratory disease. | | 1959 | 13649352 |
| adenovirus infections within a family cohort in iran. | adenovirus is one of the most frequent viruses associated with acute respiratory infections (ari). there is limited information of its transmission within the community. | 2009 | 19598232 |
| repair of large cranial defects by hbmp-2 expressing bone marrow stromal cells: comparison between alginate and collagen type i systems. | despite a wide range of available sources for bone repair, significant limitations persist. to bioengineer bone, we have previously transferred adenovirus-mediated human bmp-2 gene into autologous bone marrow stromal cells (msc). we have successfully repaired large, full thickness, cranial defects using this approach. we report now the effectiveness of various hydrogels as the scaffold for this type of bone regeneration, comparing specifically alginate with type i collagen. cultured msc of minia ... | 2010 | 20186742 |
| construction of gene transfer vectors based on simian adenovirus 7. | the complete nucleotide sequence of an isolate of simian adenovirus 7 (sadv-7) was determined. the genome organization of this isolate was found to be similar to that of other primate adenoviruses with two principal notable points; severe truncation of the e1a and e1b 19k proteins and an e3 region encoding only the 12.5k homolog. the viral gene products of sadv-7 are most closely related to simian adenovirus 1 (sadv-1), and like sadv-1, are related to the human adenovirus species hadv-f, such as ... | 2011 | 21562118 |
| impact of human adenovirus serotype 7 in hospitalized children with severe fatal pneumonia in the philippines. | human adenovirus (hadv) serotype 7 is an important etiological agent of severe childhood pneumonia. the aim of this study was to define the role of hadv7 and to describe its clinical and molecular epidemiological characteristics in the philippines in 2011. hadvs were detected by viral culture, and a partial region of hexon gene was sequenced. a total of 700 patients were enrolled, of which 22 (3.1%) died. nine (1.3%) hadv cases were confirmed, of which 7 were positive for hadv7, 1 for hadv3, and ... | 2014 | 24647252 |
| antiviral activity of folium isatidis derived extracts in vitro and in vivo. | folium isatidis is a native chinese herbaceous plant widely used for medicinal purposes for thousands of years. however, few studies have focused on the leaves of isatis indigotica. in this report, we isolated a series of four fractions (i-iv) from folium isatidis and explored the antiviral activity of each tested extract. the extracts were active against a panel of rna and dna viruses in vitro, namely influenza a virus (iav), coxsackie virus b3 (cvb3), respiratory syncytial virus (rsv), and ade ... | 2013 | 23895163 |
| outbreak of acute respiratory disease caused by human adenovirus type 7 in a military training camp in shaanxi, china. | outbreaks of ard associated with hadv have been reported in military populations in many countries. here, we report an ard outbreak caused by hadv-7 in a military training camp in shaanxi province, china, from february to march of 2012. epidemic data and samples from the patients were collected, and viral nucleotides from samples and viral isolations were detected and sequenced. igg and iga antibodies against hadv, and the neutralization antibodies against the viral strain isolated in this outbr ... | 2013 | 23734976 |
| [pneumonia due to adenovirus type 7: a case report in a healthy infant.] | a 15-month-old boy treated with amoxicillin and clavulanic acid therapy for 8 days was admitted for persistent gastroenteritis and fever. he received ceftriaxone for pneumonia modified on day 4 for cefotaxime and josamycin due to extension of alveolar lesions. on day 7, persistent fever and worsened respiratory distress led to addition of rifampicin. the child was then admitted to an intensive care unit. a hemophagocytic syndrome was suspected based on clinical signs and laboratory findings and ... | 2011 | 21571511 |
| an outbreak of adenovirus type 7 in a residential facility for severely disabled children. | background:: adenoviruses cause a variety of clinical symptoms, involving the respiratory, gastrointestinal, urogenital, and neurologic systems. only a few of the 55 known serotypes of adenovirus that affect humans can cause outbreaks of respiratory tract infection. aim:: to describe the characteristics and clinical manifestations of severe respiratory disease contracted by 8 physically and cognitively disabled children during a very short outbreak of adenovirus serotype 7 infection in a residen ... | 2011 | 21694661 |
| A naturally occurring human adenovirus type 7 variant with a 1743 bp deletion in the E3 cassette. | Human adenovirus type 7 (HAdV-7) is an important cause of acute respiratory disease (ARD). Different genomic variants of HAdV-7 have been described, designated 7a to 7l. In a previous study to investigate risk factors for ARD and wheezing, nasopharyngeal samples were collected from 90 ill children seeking medical attention in Ribeir+úo Preto, SP, Brazil. HAdVs were identified in 31 samples and were characterized by serum neutralization and genome restriction analysis. Eleven HAdVs were identifie ... | 2011 | 21677090 |
| adenovirus type 7 pneumonia in children who died from measles-associated pneumonia, hanoi, vietnam, 2014. | during a 2014 measles outbreak in vietnam, postmortem pathologic examination of hospitalized children who died showed that adenovirus type 7 pneumonia was a contributory cause of death in children with measles-associated immune suppression. adenovirus type 7 pneumonia should be recognized as a major cause of secondary infection after measles. | 2016 | 26926035 |
| crystal structure of the fibre head domain of bovine adenovirus 4, a ruminant atadenovirus. | in adenoviruses, primary host cell recognition is generally performed by the head domains of their homo-trimeric fibre proteins. this first interaction is reversible. a secondary, irreversible interaction subsequently takes place via other adenovirus capsid proteins and leads to a productive infection. although many fibre head structures are known for human mastadenoviruses, not many animal adenovirus fibre head structures have been determined, especially not from those belonging to adenovirus g ... | 2015 | 25994880 |
| novel antiviral compounds against gastroenteric viral infections. | viral gastroenteritis is a serious viral infection which affects a large number of individuals around the world, most of them being children. the infection may occur due to different viruses, for example, coxsackievirus, adenovirus, and rotavirus. there is no available cure for such infections, and the treatment mainly depends on hospitalization and administration of nutritional supports. a new antiviral agent against gastroenteritis viral infection will be a breakthrough in healthcare. pyrrole ... | 2015 | 25704120 |
| molecular characterisation of fowl adenovirus type 7 isolated from poultry associated with inclusion body hepatitis in poland. | the fowl adenovirus field strain fadv-jsn-5/10j (genbank accession number kp879219) was isolated from the intestine of a 7-week-old chicken diagnosed with inclusion body hepatitis and simultaneously with marek's disease, and for that reason, it was chosen for molecular study. it was identified as fowl adenovirus genotype 7 (species fowl aviadenovirus e) based on nucleotide sequence analysis of the loop l1 region of the hexon gene. nucleotide sequence alignment of this strain, fadv-7 reference st ... | 2017 | 28160143 |
| vaccines within vaccines: the use of adenovirus types 4 and 7 as influenza vaccine vectors. | adenovirus types 4 and 7 (ad4 and ad7) are associated with acute respiratory distress (ard). in order to prevent widespread ad-associated ard (ad-ard) the united states military immunizes new recruits using a safe and effective lyophilized wildtype ad4 and ad7 delivered orally in an enteric-coated capsule. we cloned ad4 and ad7 and modified them to express either a gfp-luciferase (gfpluc) fusion gene or a centralized influenza h1 hemagglutinin (ha1-con). balb/c mice were injected with gfpluc exp ... | 2014 | 24280656 |
| increased mucosal cd4+ t cell activation in rhesus macaques following vaccination with an adenoviral vector. | the possibility that vaccination with adenovirus (adv) vectors increased mucosal t cell activation remains a central hypothesis to explain the potential enhancement of hiv acquisition within the step trial. modeling this within rhesus macaques is complicated because human adenoviruses, including human adenovirus type 5 (hadv-5), are not endogenous to macaques. here, we tested whether vaccination with a rhesus macaque-derived adenoviral vector (simian adenovirus 7 [sadv-7]) enhances mucosal t cel ... | 2014 | 24829340 |
| an electron microscope study of the early association between two mammalian viruses and their hosts. | early interaction between two animal viruses, vaccinia and adenovirus 7, which multiply readily in l strain and hela cells, respectively, was examined in both whole mount preparations and in thin sections. to observe the association at the surface, cells carrying adsorbed virus were swelled under controlled conditions and then "stained" with neutral phosphotungstate. each particle of both virus types becomes attached to the cell by several capsomeres and is then ingested by phagocytosis. within ... | 1962 | 13883196 |
| [familial epidemic of adenovirus type 7 disease with encephalitic and blood manifestations]. | | 1964 | 14135064 |
| novel 1,2,5-oxadiazine derivatives--synthesis and in vitro biological studies. | a new synthetic approach to the 1,2,5-oxadiazine ring system is described. 2-substituted or 2,4-disubstituted 2h-1,2,5-oxadiazine-3,6(4h,5h)-dione derivatives 4 were prepared by cyclisation of hydroxamic acids 3 derived from n-(1-benzotriazolylcarbonyl)-amino acids 1. the structures of the synthesised compounds were fully characterised by ir, 1h and 13c nmr spectroscopy and elemental analysis. the aim of this study was to evaluate biological activity of the newly synthesised oxadiazine derivativ ... | 2003 | 14769241 |
| adenovirus type 7 induces interleukin-8 in a lung slice model and requires activation of erk. | adenovirus (ad), particularly ad type 7 (ad7), causes severe lung infection and pneumonia. initially, ad causes neutrophilic inflammation of the distal airways and alveoli. interleukin-8 (il-8) is the major lung neutrophil chemotaxin, and we have shown that ad7 induces il-8 release from the a549 alveolar epithelial cell line. we sought to determine whether ex vivo human and bovine lung tissue containing primary pneumocytes could be used as a more accurate and relevant model to study ad acute inf ... | 2004 | 15047831 |
| ten-year analysis of adenovirus type 7 molecular epidemiology in korea, 1995-2004: implication of fiber diversity. | adenovirus type 7 (ad7) is frequently responsible for severe respiratory infections, especially in young infants. since the ad7 epidemics have been associated with severe childhood pneumonia and significant mortality in korea, 1995-1999, continuous surveillance was necessary for ad7 related diseases. | 2006 | 16458589 |
| influence of sv40 genome on the replication of an adenovirus-sv40 "hybrid" population. | feldman, l. a. (baylor university college of medicine, houston, tex.), j. l. melnick, and f. rapp. influence of sv40 genome on the replication of an adenovirus-sv40 "hybrid" population. j. bacteriol. 90:778-782. 1965.-replication of a type 7 adenovirus-sv40 hybrid population in primary african green monkey kidney cells was accompanied by the formation of sv40 tumor antigen, adenovirus antigens, and cytopathic changes characteristic of adenovirus infection. prior infection of the cultures with sv ... | 1965 | 16562080 |
| density differences between hybrid and nonhybrid particles in two adenovirus-simian virus 40 hybrid populations. | the adenovirus 7-simian virus 40 hybrid virus population e46(+) was subjected to fixed-angle equilibrium density gradient centrifugation in cscl. a difference in buoyant density between the hybrid virion and its nonhybrid adenovirus 7 counterpart was noted, the hybrid virion possessing the lower buoyant density. this difference in buoyant density appeared to be accentuated in a population of adenovirus 2(+t7), a derivative of e46(+) in which the adenovirus 7-simian virus 40 genome had been trans ... | 1970 | 16789126 |
| calcium-dependent viral internalization is required for adenovirus type 7 induction of il-8 protein. | the host response to adenovirus (ad) infection involves induction of cytokines in lung epithelia. we have demonstrated induction of the lung neutrophil chemokine interleukin-8 (il-8) by ad7, a major lung pathogen, in a549 lung epithelial cells and lung tissue through activation of the erk signaling pathway. however, the mechanism of il-8 induction is still unclear. in this paper, we first showed that ad7 viral gene expression is not essential for il-8 induction as psoralen-uv inactivation of ad7 ... | 2006 | 16890267 |
| generation of neutralizing monoclonal antibodies against a conformational epitope of human adenovirus type 7 (hadv-7) incorporated in capsid encoded in a hadv-3-based vector. | the generation of monoclonal antibodies (mabs) by epitope-based immunization is difficult because the immunogenicity of simple peptides is poor and t cells must be potently stimulated and immunological memory elicited. a strategy in which antigen is incorporated into the adenoviral capsid protein has been used previously to develop antibody responses against several vaccine targets and may offer a solution to this problem. in this study, we used a similar strategy to develop hadv-7-neutralizing ... | 2014 | 25054273 |
| antigenic variability among two subtypes of human adenovirus serotype 7. | human adenovirus type 7 (hadv-7) is one of the major serotypes responsible for acute respiratory infection. it is important to investigate the antigenic variabilities of different hadv-7 genomic subtypes for vaccine development. phylogenetic analysis of global hadv-7 strains and major antigen proteins showed that hadv-7 could be classified into two subtypes. there were three highly variable regions (hvr1, hvr4, and hvr7) in the hexon protein that varied between subtypes. within each of the subty ... | 2014 | 24760574 |
| clinical features of community acquired adenovirus pneumonia during the 2011 community outbreak in southern taiwan: role of host immune response. | human adenovirus 7 (hadv-7) was responsible for a significant number of fatalities during the 2011 community outbreak in taiwan. the mechanisms underlying the pathogenesis of severe adenovirus infections in non-immunocompromised individuals remain unclear. adenovirus pneumonia was associated with pleural effusion in a number of patients from the 2011 outbreak suggesting that similar to bacterial pneumonia, patients diagnosed with adenovirus pneumonia who have pleural effusion are more severely a ... | 2017 | 28270104 |
| effective concentration, recovery, and detection of infectious adenoviruses from environmental waters. | current application of fecal indicator bacteria (fib) as an indicator of sewage contamination has its limitation and other alternative indicator systems are needed for enhanced monitoring of recreational water quality. to explore the potential use of human enteric viruses (hev) as a potential indicator, human adenovirus type 7 (hadv-7) was tested in this study as a model virus. through spiked hadv-7 into the sample seawater, different procedures for viral concentration and elution were comparati ... | 2016 | 26763204 |
| efficient induction of cross-presentating human b cell by transduction with human adenovirus type 7 vector. | although human autologous b cells represent a promising alternative to dendritic cells (dcs) for easy large-scale preparation, the naive human b cells are always poor at antigen presentation. the safe and effective usage record of human adenovirus type 7 (hadv7) live vaccines makes it attractive as a promising vaccine vector candidate. to investigate whether hadv7 vector could be used to induce the human b cells cross-presentation, in the present study, we constructed the e3-defective recombinan ... | 2016 | 26620361 |
| heterologous prime-boost regimens with a recombinant chimpanzee adenoviral vector and adjuvanted f4 protein elicit polyfunctional hiv-1-specific t-cell responses in macaques. | hiv-1-specific cd4+ and cd8+ t lymphocytes are important for hiv-1 replication control. f4/as01 consists of f4 recombinant fusion protein (containing clade b gag/p24, pol/rt, nef and gag/p17) formulated in as01 adjuvant system, and was shown to induce f4-specific polyfunctional cd4+ t-cell responses in humans. while replication-incompetent recombinant hiv-1/siv antigen-expressing human adenoviral vectors can elicit high-frequency antigen-specific cd8+ t-cell responses, their use is hampered by w ... | 2015 | 25856308 |
| human adenovirus type 7 infection associated with severe and fatal acute lower respiratory illness and nosocomial transmission. | a 23-year-old male died of severe pneumonia and respiratory failure in a tertiary hospital in beijing, and 4 out of 55 close contacts developed fever. molecular analysis confirmed human adenovirus type 7 (hadv7) as the causative agent. we highlight the importance of early diagnosis and treatment and proper transmission control of hadv7. | 2015 | 25520444 |
| synthesis and antiviral evalution of some novel pyrazoles and pyrazolo[3,4-d]pyridazines bearing 5,6,7,8-tetrahydronaphthalene. | the enaminone 2 was reacted with hydrazonyl halides 3a-d to afford the corresponding pyrazole derivatives (6a-d) which reacted with hydrazine hydrate to afford the new pyrazolo[3,4-d]pyridazine derivatives 7a-d, respectively. in addition, compound 2 was reacted with some primary aromatic amines to afford the corresponding secondary enaminones 10a-c and reacted with sulfapyridine or sulfapyrimidine to afford the corresponding sulfonamide derivatives 12a and 12b. evaluation of these new compounds ... | 2013 | 23610964 |
| a retrospective study of disease in elasmobranchs. | this report reviews diseases of 1546 elasmobranchs representing at least 60 species submitted to northwest zoopath from 1994 to 2010. cownose rays (rhinoptera bonasus) (78), southern rays (dasyatis americana) (75), dusky smooth-hounds (mustelus canis) (74), bonnethead sharks (sphyrna tiburo) (66), and bamboo sharks (hemiscylliidae) (56) were the most commonly submitted species. infectious/inflammatory disease was most common (33.5%) followed by nutritional (11.9%, mostly emaciation), traumatic ( ... | 2013 | 23528944 |
| complete genome sequence of human adenovirus type 7 associated with fatal infant pneumonia. | the chinese human adenovirus 7 (hadv7) 0901hz/shx/chn/2009 was isolated from the hydrothorax fluid of an infant with fatal pneumonia in shaanxi, china, in 2009. comparison of the entire genome with the genomes of the other 10 strains of hadv7 from genbank revealed homologies of 89.9 to 99.9%, with geographic polymorphism among hadv-7 field strains circulating in mainland china. | 2013 | 23409258 |
| human adenovirus type 7 outbreak in police training center, malaysia, 2011. | in march 2011, an outbreak of acute respiratory disease was reported at the kuala lumpur (malaysia) police training centre. approximately 100 trainees were hospitalized and 5 were admitted to the intensive care unit. three of these 5 trainees died. human adenovirus type 7 was identified as the etiologic agent. | 2012 | 22515984 |
| adenovirus pneumonia in an immunocompetent adult. | adenovirus pneumonias are reported relatively commonly in pediatric or immunocompromised patients, but the clinical presentation of adenovirus pneumonia in immunocompetent hosts is not well known. we treated an immunocompetent 42-year-old man with mild adenovirus pneumonia following pharyngitis and conjunctivitis. diagnosis was established on the basis of chest radiologic findings, detection of adenovirus type 7 dna by pcr assay in material obtained from bronchoalveolar lavage (bal), and a great ... | 2012 | 22350400 |
| molecular classification of human adenovirus type 7 isolated from acute respiratory disease outbreak (ard) in korea, 2005-2006. | to assess the genomic characteristics of human adenoviruses (hadvs) that caused small-scale epidemics in korea and compare sequence analysis and restriction fragment length polymorphism (rflp). | 2010 | 24159434 |
| [cloning of 0-17.5 mu and sequencing of 0-4.8 mu of the lefe and dna of the ad7 vaccine strain left end]. | cloning of 0-17.5 mu dna fragment of adenovirus 7 vaccine strain and sequencing of 0-4.8 mu fragment (1,737 bp). | 1999 | 12569780 |
| [detection of a new genomic variation of adenovirus 7 associated to severe infections of the lower respiratory tract]. | we report a new genomic variation of adenovirus 7, associated to severe infections of the lower respiratory tract isolated during september 1990, from children under 3 years of age and living in buenos aires city. the restriction analysis with the bamhi, bgli, bglii and smai restriction endonucleases demonstrated that the new variation is highly related to the recently described adenovirus 7h. | 1993 | 8114625 |
| molecular epidemiology and restriction site mapping of adenovirus 7 genome types. | from the united states, the federal republic of germany, and other regions, 168 strains of av7, isolated between 1961 and 1985, were analyzed by six restriction endonucleases and nine genome types were identified. the enzymes bamhi and hindiii were most discriminative. the genome type d5 (or 7b) predominated with 120 isolates since 1970 in both countries. strains of d2 (7a) and d4 (7c) were isolated for a limited time, d3 for an extended time period. several clusters of infections with the same ... | 1989 | 2548461 |
| in vitro cell transformation screening of 4 toluene diamine isomers. | 2,4-, 2,5-, 2,6- and 3,4-toluene diamine (tda) were tested for their ability to enhance the transformation of primary hamster embryo cells (hec) by simian adenovirus 7 (sa7) when administered either prior to or after virus inoculation and for their ability to transform secondary hec. 2,4-tda was inactive when given prior to sa7, but active if given after. 2,5-tda was active in both protocols. 2,6-tda was marginally active if administered before virus and was the most active of the isomers when a ... | 1980 | 7442705 |
| induction of neoplasia in vitro in hamster kidney tissue by adenovirus 7-sv40 "hybrid" strain (lle46). | | 1966 | 5327111 |
| [on an intrahospital epidemic episode of acute respiratory disease due to adenovirus 7]. | | 1965 | 14341351 |
| [cellular lesions induced by adenovirus 7 & 7 alpha]. | | 1957 | 13498464 |
| co-infection of fowl adenovirus with different immunosuppressive viruses in a chicken flock. | in poultry, fowl adenovirus (fadv) and immunosuppressive virus co-infection is likely to cause decreased egg production, inclusion body hepatitis, and pericardial effusion syndrome. in this study, fowl adenovirus infection was found in parental and descendent generations of chickens. we used quantitative polymerase chain reaction (pcr) and dot blot hybridization to detect the infection of reticuloendotheliosis (rev), avian leukosis virus (alv), and chicken infectious anemia virus (ciav) in 480 p ... | 2018 | 29509913 |
| effect of growth rate and simian adenovirus-7 transformation on in vitro 67ga binding to hamster embryo cells. | the influence of growth rate and malignant transformation on 67ga uptake was studied using cultured hamster embryo fibroblasts. normalnonconfluent cells in log phase of growth bound approximately twice as much isotope as did confluent cells in a plateau phase of growth. in contrast, cells transformed by simian adenovirus-7 (sa-7), which were also undergoing log growth, bound almost no 67ga. these results suggest that, although the rate of cellular proliferation may influence tissue affinity for ... | 1975 | 803556 |
| analysis of multiple viral genome fragments in adenovirus 7-transformed hamster cells. | the presence of multiple copies of a portion of the viral genome was demonstrated in ad7-transformed cells by a new method based on the kinetic analysis of labeled viral dna reassociation in the presence of unlabeled transformed cell dna. dna-dna homology measurement utilizing defined dna fragments (restriction endonuclease digests) as labeled probes supported the above conclusion. | 1975 | 1057486 |
| effect of cyclophosphamide on syngeneic transplantation of para-adenovirus-7-transformed tumor cells in hamsters. | | 1972 | 4660941 |
| tumor induction in hamster by para(3ct)-adenovirus 7 mutant. morphology and antigenic profiles of neoplastic cells. | | 1971 | 4332901 |
| variations in immunogenicity of disrupted cells prepared from an adenovirus-7 hamster tumor cell line. | | 1971 | 5088045 |
| concomitant immunity in hamsters bearing syngeneic transplants of tumors induced by para-adenovirus 7, simian adenovirus 7, or 9,10-dimethylbenzanthracene. | | 1971 | 4325852 |
| antigenic and oncogenic properies of a cell line derived frm a hamster brain tumor induced by simian adenovirus 7. | | 1969 | 4311052 |
| [epidemics of acute diseases of the respiratory system due to adenovirus 7 in premature infants]. | | 1967 | 4307603 |