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[influence of parotin on the repressing action of cyanylethyl group to histamine stress (author's transl)]. 197895057
[studies of acid-soluble antigens in several strains of the genus bacillus for orienting purposes (author's transl)].by acid hydrolysis (0.2 n hcl) it was possible to obtain extracts from nonsporulated cells of different strains of 5 species of the genus bacillus which were composed mainly or solely of species-specific antigens. this was the result of experiments using the immunodiffusion technique after having prepared antisera from rabbits with the aid of hcl extracts. cross-reacting antibodies were adsorbed easily. the species-specific reacting antisera revealed the existence of group- or strain-specific an ...197995076
studies of the levels of hydrolytic enzymes & insulin content in rat pancreas on preincubation with trasylol. 197995115
cytogenetic analysis of double satellites on marker chromosome no. 14. 197995131
tumor immunology in domestic animals. 197995155
membrane surface properties of sheep erythrocytes, an immunological reagent, after different treatments as reflected by partition in two-polymer aqueous phases.sheep erythrocytes (e) which, with or without certain treatments, are currently used as "immunological reagents" to detect cells with specific receptors (by rosette-formation) have been partitioned in two-polymer aqueous-phase systems selected so as to reflect charge-associated or lipid-related membrane surface properties. we have found that the partitioning behavior of e is not affected in these phases by reacting the cells with anti-e antibody (either igg or igm), forming ea. the additional bi ...197995174
effects of ovarian hormones on cell membranes in the rat uterus. i. freeze fracture studies of the apical membrane of the liminal epithelium.freeze fracture techniques have been used to study the apical membrane of cells of the luminal epithelium of the rat uterus under various hormonal regimes. in the ovariectomized but otherwise untreated rat, intramembranous particles (imps) occur at a density of 1395 +/- 122 per micron 2; they appeared spherical and uniformly distributed. after 3 days treatment with estrogen, no change in appearance or density was found, but 3 days of progesterone treatment produced a significant increase in imp ...197995176
the development of the his bundle recording technique. 197995286
antigenic similarity between squamous cell carcinoma of horn (horn cancer) and normal bovine foetal tissues.normal bovine foetal (liver and skin) and horn cancer tissue antigens were examined using double diffusion agar gel precipitation and immuno-electrophoretic tests to detect any cross reactivity among them. rabbit horn cancer antisera absorbed with normal bovine liver, skin and horn core epithelium antigens, when tested with foetal skin and liver (4 to 6 months of gestation), revealed the presence of 2 foetal antigens in horn cancer. immuno-chemically 2 of the horn cancer antigens were found to b ...197995358
[the effect of bile acids on the cholesterol metabolism of the liver]. 197995366
human t cell subpopulations as defined by fc receptors. 197995424
regulation of the mitochondrial anabolism at low concentrations of thyroid hormones and by some of their structural analogues.the authors demonstrate that the in vitro stimulation of mitochondrial rna synthesis produced by thyroid hormones takes place also at physiological levels, equal to those held in the liver cells of experimental animals. two groups of male rats have been used: normal control animals (n) and animals surgically thyroidectomized on the 25th day of life (t). the animals were fed and kept in standard conditions and killed on the 85th day of life. the purification of mitochondrial samples and the deter ...197995433
[antitumor activity and preclinical pharmacologic evaluation of pingyangmycin (author's transl)]. 197995444
[myelin].the lipid and protein composition and the metabolic turnover of myelin in the c.n.s., are briefly reported. for a better understanding, it seemed useful to introduce some historical data on the discovery of myelin and to give a morphological description at structural and ultrastructural level.197895501
field trials of slow-release formulations of chlorpyrifos and malathion for the control of chagas's disease vectors. 197995561
effect of neurotensin, substance p and morphine sulfate on the secretion of prolactin and growth hormone in the rat.neurotensin (nt), substance p (sp) and morphine sulfate (ms) elevate plasma prolactin and growth hormone levels in both normal or estrogen-progesterone pretreated male rats. by contrast, steroid priming is required for trf to exhibit prl-releasing activity. naloxone, an opiate receptor blocker, reverses the stimulatory effect of ms only. diphenhydramine, a histamine antagonist, inhibits the response to nt, sp and ms without affecting the response to trf. these results suggest the involvement of ...197795701
group f, a new vibrio? 197795779
[immunocytochemical location of the centrosphere of human cancer cells using natural rabbit antibodies].sera of 40 normal nonimmunized rabbits were eprouved by immunoperoxidase on cultural human cells. four sera contain centrosphere-reactive antibodies and for the strongest serum the centrospheres were still stained with the 1/600 dilution. this last serum visualized the centrospheres within the height human cell lines eprouved, whatever the phase of the mitotic cycle. the staining was not inhibited after serum absorption by tubulin.197895892
[inhibition by the enterotoxin of vibrio cholerase of meiosis reinitiation of the xenopus laevis oocyte induced in vitro by progesterone].progesterone reinitiates in vitro meiosis in xenopus laevis oocytes. this action of the hormone can be abolished by the exotoxin of vibrio cholerae. the concentration of toxin which inhibits 50% of the progesterone (10 mum) action in about 2.5 pm. binding experiments using 125i labelled toxin demonstrated the existence of high affinity binding sites (kd approximately 0.2 nm) located probably on the surface of the oocytes.197895900
the response of experimental animal tumors to neutron radiation therapy. 197796056
viability and endogenous substrates used during starvation survival of rhodospirillum rubrum.cells of rhodospirillum rubrum were grown photoorganotrophically and chemoorganotrophically and then starved for organic carbon and combined nitrogen under four conditions: anaerobically in the light and dark and aerobically in the light and dark. illumination prolonged viability and suppressed the net degradation of cell material of phototrophically grown cells, but had no effect on chemotrophically grown cells that did not contain bacteriochlorophyll. the half-life survival times of carbohydra ...197896087
biosynthesis of exopolysaccharide by pseudomonas aeruginosa.in batch cultures of pseudomonas aeruginosa, the maximum rate of exopolysaccharide synthesis occurred during exponential growth. in nitrogen-limited continuous culture, the specific rate of exopolysaccharide synthesis increased from 0.27 g g of cell-1 h-1 at a dilution rate (d) of 0.05 h-1 to 0.44 g g of cells h-1 at d=0.1 h-1. the yield of exopolysaccharide on the basis of glucose used was in the range of 56 to 64%. exopolysaccharide was also synthesized in carbon-limited cultures at 0.19 g g o ...197896088
lower levels of thyrotropin-releasing hormone-degrading activity in human cord and in maternal sera than in the serum of euthyroid, nonpregnant adults.thyrotropin-releasing hormone (trh)-degrading activity was investigated in human cord, maternal, and euthyroid adult sera by measuring (a) the rate of disappearance of trh and (b) the rate of formation of degradation products. the rate of trh degradation in cord and maternal sera was 25-33% of that in euthyroid adult serum. concomitantly, in cord and maternal sera, the rate of formation of proline, a major trh degradation product in serum, was one-quarter to one-third that in euthyroid adult ser ...197896140
intrathecal gentamicin for refractory gram-positive meningitis.the mortality for meningitis due to staphylococcus aureus or listeria monocytogenes remains high, ranging from 32% to 77%. we treated a patient with staphylococcal meningitis refractory to methicillin sodium and oxacillin sodium, and a patient with listeria meningitis refractory to penicillin g potassium and ampicillin sodium; both patients were cured when intrathecal gentamicin sulfate was added to the regimen. the combination of intrathecal gentamicin and a penicillin may be beneficial in refr ...197896281
[influence of chenodeoxycholic acid on the metabolism of cholesterol and bile acids in the course of cholesterol gallstone formation in squirrel monkeys (author's transl)]. 197896290
dietary restrictions early and late: effects on the nephropathy of the nzb x nzw mouse.nzb x nzw f1 mice initiated on calorie restriction at weaning or at 4 to 5 months of age or initiated on moderate protein restriction at weaning, were afforded significant protection from the development of immune nephritis. whereas animals on normal calorie intake demonstrated deposition of immune reactants in glomerular basement membrane-oriented pattern, those on either protein or calorie restriction exhibited mesangial confinement of immunoglobulins and complement. associated with these dive ...197896299
effect of fetal tissue on experimental (7,12-dimethylbenz[a]anthracene) breast cancer in rats. 197896305
bordetella pertussis in a partially immunized host: case report. 197896376
a limited serological survey of north island cattle for antibody to a number of endemic viruses. 197796390
a review: extracellular volume in the brain--the relevance of the chloride space. 197896413
pre-proparathyroid hormone; amino acid sequence, chemical synthesis, and some biological studies of the precursor region.the precursor of bovine proparathyroid hormone was synthesized by translation of parathyroid mrna in a wheat-germ cell-free system. the amino acid sequence of the nh2-terminal extension (the pre sequence) was determined by repetitive edman degradation of the polypeptide labeled with radioactive amino acids (radiosequencing). the pre sequence of pre-proparathyroid hormone is (formula: see text) which is followed by the sequence of proparathyroid hormone. it is significant that 20 of the 25 amino ...197896437
chromosomal locations of mouse immunoglobulin genes.the chromosomal locations of the structural genes coding for the constant portions of mouse heavy (h) and light chain immunoglobulins were studied by molecular hybridization techniques. complementary dna probes containing the constant-region sequences of kappa and lambdai light chain and alpha, gamma2b, and mu heavy chain mrnas were annealed to a large excess of dna from a series of eight mouse-human hybrid cell lines that are deficient for various mouse chromosomes. the lines were scored as pos ...197896442
brain and liver aldehyde dehydrogenase activity and voluntary ethanol consumption by rats: relations to strain, sex, and age.voluntary ethanol consumption and brain and liver aldehyde dehydrogenase (aldh) activity were measured in male and female rats of the tryon maze-bright (s1), tryon maze-dull (s3), and wistar strains. the levels of brain aldh measured in the different groups, corresponded well to the levels of ethanol consumption, while differences in liver aldh corresponded well to only the strain differences in ethanol intake. within individual groups, levels of ethanol consumption correlated better with levels ...197896475
haplotype designations of various strains of guinea pigs. 197896556
[the effect of proteins from tannery wastes on body proteins in birds].the effect of 7.0% and 3.5% proportion of lime protein, produced according to the patent csp 133.077, in the diet was studied under laboratory conditions, as exerted on the growth rate of japanese quail (coturnix coturnix japonica) and on the level of serum proteins and keratins in the feathers of these birds. the second generation of quail fed this diet showed an improvement of growth at the final stage and significant internal changes in the protein spectrum of the blood serum. electrophoresis ...197896565
[observation on the antigenic affinity of leptospira and brucella in the serological examination of cattle].36,9% bovine serums which showed a non-specific reaction in examination for brucellosis had titre greater than or equal to 1:400 leptospirosis agglutinins. 15.1% of the serums showed a positive reaction (greater than 1:800), mostly those against l. sejroe and l. grippotyphosa. the cross reactions, found in individual cases within up to 39 days since the first reaction to brucellosis in cattle may signalize early leptospira infections.197896568
[diagnosis of vibriosis in bulls at breeding stations through lavages of the artificial vagina].the objective of the study was to test the suitability of lavages of artificial vaginas which are used for collecting ejaculate for diagnosing the campylobacter fetus subsp. fetus germs. according to the results of the investigation this method may be considered equal to the method of lavages of the prepuce. however, it is important to point out the advantages: it eliminates the danger of an accident, it enables quality lavage in the laboratory. to caputure the campylobacter fetus the filtration ...197896573
a sarcocystis-like protozoon in a sheep with lymphadenopathy and myocarditis.a generalized enlargement of the lymph nodes was found in an emaciated adult ewe. additional autopsy findings included tiny grey-white necrotic foci in the heart muscle, aspiration pneumonia and diffuse pleuritis. light microscopy showed a generalized lymphadenopathy with perilymphadenitis, depletion of lymphocytes and histiocytosis of the lymph node. in histiocytes and vascular endothelial cells of lymph nodes, septal capillary endothelium of lungs and capillary endothelium of myocardium, early ...197896578
the organization, composition and matrix of hepatocyte nuclei exposed to alpha-amanitin.alterations in the structure and molecular composition of avian hepatocyte nuclei were compared following administration in vivo of lethal and sub-lethal doses of alpha-amanitin. this toxin interferes with extranucleolar transcription by direct inhibition of rna polymerase ii activity. the resultant effects include: extensive condensation of chromatin, displacement of nucleoplasmic contents and fragmentation of nucleoli. changes in nuclear morphology were quantitated by stereometry and related t ...197896580
[isolation of cationic proteins from rabbit thrombocytes and study of their bacteriostatic activity].cation-containing proteins, which possessed the bacteriostatic activity against grampositive microorganism bacillus subtilis shgw, were isolated from rabbit thrombocytes by means of selective extraction. these substances were of heterogenous nature (as shown by polyacrylamide gel disc electrophoresis), including two groups of proteins with molecular weight about 8=10-10(3) and 20=30-10(3) daltons. the bacteriostatic activity of each group of these proteins was studied after gel filtration of the ...197896596
[comparison between t4 (c) and t4 (d)]. 197896624
[biological properties and mechanisms of development of bacteria resistant to fusidin, erythromycin and chloramphenicol]. 197896638
phospholipid content and activity of pure uridine diphosphate-glucuronyltransferase from rat liver.rat liver phospholipids were radioactively labeled in vivo before purification of udp-glucuronyltransferase to homogeneity. the pure enzyme contained very little phospholipid (approx. 0.7 mol of phospholipid/mol of protein). the solubilization detergent lubrol 12a9 appeared to act as a phospholipid substitute, capable of supporting udp-glucuronyltransferase activity. phospholipase c did not inhibit the pure enzyme activity and pure udp-glucuronyltransferase was stimulated by 40--100% by the addi ...197896816
mode of action of iturin a, an antibiotic isolated from bacillus subtilis, on micrococcus luteus. 197896818
behaviour of solute and particle markers in the stomach of sheep given a concentrate diet.1. fistulated sheep given a concentrate diet were used to study the behaviour of solute ([51cr]edta) and particle ([103ru]phenanthroline) markers in the stomach under conditions of continuous feeding. 2. an injection of a mixed dose of [51cr]edta and [103ru]phenanthroline was given into the rumen and the time course of marker concentrations in the rumen and the abomasum was recorded. the curves were analysed on the assumption that the stomach of the sheep could be represented as two mixing compa ...197896850
differential effects of prostaglandin synthetase stimulators on inhibition of cyclooxygenase.the different effects of prostaglandin synthetase stimulators on inhibition of the cyclooxygenase by structurally distinct classes of nonsteroidal antiinflammatory agents suggest that the enzyme is altered by interaction with these stimulators. reversible stimulation of prostaglandin synthetase activity by phenols and some other compounds and the relative influence of these stimulators on inhibitors of the cyclooxygenase were determined quantitatively. two distinct classes of inhibitors were est ...197896853
phycobiliprotein synthesis in protoplasts of the unicellular cyanophyte, anacystis nidulans.stable and metabolically active protoplasts were prepared from the unicellular cyanophyte, anacystis nidulans, by enzymatic digestion of the cell wall with 0.1% lysozyme. the yield of protoplasts from intact algal cells was approx. 50%. incorporation of l-[u-14c]leucine into cold trichloroacetic acid-insoluble material from protoplasts preparations was linear for 1.5 h and continued for an additional 2.5 h. incorporation of radiolabeled leucine into hot trichloroacetic acid-insoluble material fr ...197896857
the purification, properties and characterization of three forms of alpha-l-fucosidase from monkey brain.alpha-l-fucosidase (alpha-l-fucoside fucohydrolase, ec 3.2.1.51) has been purified to apparent homogeneity (about 22 000-fold over the crude homogenate) from monkey brain. values of kinetic constants for the purified enzyme were as follows: ph optimum, 5.0; km, 0.22 mm; v, 913 mumol/mg per h. alpha-l-fucose was a competitive inhibitor (ki, 0.275 mm) of the enzyme. evidence for the involvement of sulphydryl group(s) and carboxyl group containing amino acid(s) in the catalytic process is presented ...197896860
nitrogen fixation and hydrogen metabolism in photosynthetic bacteria.the photosynthetic bacteria are found in a wide range of specialized aquatic environments. these bacteria represent important members of the microbial community since they are capable of carrying out two of the most important processes on earth, namely, photosynthesis and nitrogen fixation, at the expense of solar energy. since the discovery that these bacteria could fix atmospheric nitrogen, there has been an intensification of studies relating to both the biochemistry and physiology of this pr ...197896875
role of carbohydrate residues of human chorionic gonadotropin in stimulation of progesterone secretion by cultures of monkey granulosa cells. 197896881
[nature of changes in the level of steroid hormones and their precursors in peripheral blood of papio monkeys under stress].the radioimmunological method was applied to determination of changes in the peripheral blood plasma level of 12 steroids in male papio hamadryas under immobilization and surgical stress. androgen content decreased, and the concentration of steroid hormone precursors and hydrocortisone blood plasma content rose in response to stress. these changes were in contraphase with the circadian steroid rhythms. the most objective and sensitive criteria of the stress situation evaluation were decrease of ...197896885
[physico-chemical properties of microbial antigens and the immuno-allergic tests].experiments were conducted on guinea pigs sensitized by the delayed and immediate types of allergy. different antigens obtained from the strain of brucella abortus ba-19 were used for sensitization and the resolving action. comparison of the resolving properties of the corpuscular, soluble (ultrasound treated) antigens and purified protein fractions, polysaccharide and rna was carried out in the skin reactions of the immediate and delayed type, passive skin anaphylaxis, acute anaphylactic shock, ...197896888
test for differentiation of m. tuberculosis and m. bovis from other mycobacteria.a test is described for selective inhibition of mycobacterium tuberculosis and m. bovis isolates in fluid medium. the method employs rho-nitro-alpha-acetyl-amino-beta-hydroxy-propiophenone (nap) as an inhibitory agent for differentiation of mammalian tuberculosis strains from other mycobacteria.197896930
[serological survey of animal rickettsioses in cameroon. i. evaluation of the threshold of positivity and specificity of the micro-agglutination reaction as related to the size of the animal]. 197796947
[antimicrobial activities of two strains of streptomyces albus isolated from african soils].the antibiotic activity of these two strains of s. albus is facilitated by culture on slices of potatoes. streptomyces extracts show an antibiotic activity against gram-positive and gram-negative bacteria and an antifongic activity aginst nearly all aspergillus. these antimicrobial effects bring hope of a utilization against some mycotoxin pollution, or mold attacks.197896972
[functional study of the rat olfactory bulb by a 14c-2-deoxyglucose autoradiographic technic].the autoradiographic method has been used in the rat to map active regions in the olfactory bulb after a pulse of 14c-2-deoxyglucose with electrical stimulation of the lateral olfactory tract. the highest optical densities were found at the external plexiform, mitral, internal plexiform and granular layers; the lowest was found in the glomerular layer.197896988
[cutaneous respiration in a selachian (scyliorhinus caniculus l.)].cutaneous oxygen consumption (mo2) and cutaneous oxygen uptake from the external medium were investigated in an elasmobranch scyliorhinus caniculus l. in spite of an important mo2 (2.75 +/- 0.28 nmol.mn-1 cm-2 ; n=6) a positive net flux of oxygen through the skin takes place (2.98 +/- 0.33 nmol. mn-1 .cm-2). the skin of the dogfish in an exchanger for oxygen supplying 10% of oxygen requirements of other organs of the body in these experimental conditions (t = 13 degrees c).197897014
[kinetic study of membrane 5'-nucleotidase activity in cultured diploid cells].5'-nucleotidase activity of cultured diploïd cells was measured using intact suspended cells. this depended on the substrate amount, but did not vary with mg ++ concentration-kinetic data were determined using con. a,a specific inhibitor.197897019
[mental capacity and human consanguinity].mental abilities and inbreeding. the comparison between 1,302 adults born from consanguineous marriages underlines a heavy depression of mental abilities. the load of inbreeding equals the load of environment, both adding their influences, without interaction. homozygosity acts probably more particularly on the brain.197897024
[permeability of the isolated human amniotic membrane to divalent cations].membrane potential and resistance recordings, in vitro, show that mg++ does not pass through the amnion from the inside of the amniotic compartment to the outside of the amniotic membrane. mg++ may become fixed on the surface or in the midst of the amniotic membrane. however, mg++ diffuses in the opposite direction. ca++, ba++, sr++ diffuse in both directions across the amniotic membrane.197897026
precipitating autoantibody to a ubiquitous tissue antigen: association with rheumatoid arthritis treated with sodium aurothiomalate or d-penicillamine. 197897039
purification and characterization of the penicillin-binding protein that is the lethal target of penicillin in bacillus megaterium and bacillus licheniformis. protein exchange and complex stability.the penicillin-binding protein that is thought to be the lethal target of penicillin in bacillus megaterium (protein 1) has been purified to greater than 95% homogeneity. the membrane-bound penicillin-binding proteins were solubilized with a non-ionic detergent and partially separated from each other by ion-exchange chromatography on deae-sepharose cl-6b. protein 1 was subsequently purified by covalent affinity chromatography on ampicillin-affinose. bacillus licheniformis contains an equivalent ...197897081
hemostasis in schistosomiasis mansoni.hemostasis was studied in 18 patients with the hepato-intestinal form of schistosomiasis mansoni and in 23 with the hepato-splenic form. both groups are compared referring to alterations found. the relations between plasmatic coagulation factors and hepatocytic function tests are studied. in 6 patients the explorations were repeated after administration of hycanthone. in the patients with the hepato-splenic form, the presence of chronic consumptive coagulophathy was found. the coagulopathy disap ...197797124
[treatment of acute pancreatitis by glucagon. experimental studies in dogs].the authors made a comparative study of the use of glucagon (4 mg/day iv) in 30 dogs with acute pancreatitis. they found that the mortality and amylasemia were significantly lower in the glucagon-treated group than in the control groups (saline and glucose solution 5%). in the glucagon group, the areas of necrosis were smaller (1.5 cm) and rarely found; microscopically, the areas of necrosis and the inflammatory reaction were much smaller than in the other groups. these findings lead to the conc ...197797132
[nature of the mutations that determine the ability of bacillus subtilis a-50 to sporulate at high glucose concentrations in the medium].the ability of bacillus subtilis a-50 to sporulate in the medium containing high glucose concentrations is caused by at least two mutation types: pts mutations and cat (or tgl) mutations, both of them affecting differently the level of alkaline proteinase synthesis. the decrease of the level of enzyme activity in the case of pts mutation (glur3 mutant) occurs at the expense of glucose transport disturbance. the mutation cat (tgl) (mutant glur5) causes the increase in enzyme synthesis at the expe ...197897172
impaired host resistance to endotoxin and malaria in polychlorinated biphenyl- and hexachlorobenzene-treated mice.the in vivo effect of polychlorinated biphenyl (pcb) and hexachlorobenzene (hcb) on murine endotoxin sensitivity and resistance to malaria (plasmodium berghei nyu-2) infection was studied. the dietary administration of 167 ppm (167 microgram/g) of pcb 1242 or hcb for 3 weeks resulted in an enhanced sensitivity to gram-negative endotoxin (salmonella typhosa), which was further increased in animals maintained on the diets for 6 weeks. by 6 weeks, a 5.2- or 32-fold increase in endotoxin sensitivity ...197897225
effect of growth environment on pseudomonas aeruginosa killing by rabbit polymorphonuclear leudocytes and cationic proteins.pseudomonas aeruginosa grown in a chemostat under carbon- and magnesium-limited conditions showed varying resistance to killing by rabbit peritoneal exudate polymorphonuclear leukocytes. slow-growing (d = 0.05 h-1), magnesium-limited cells were significantly more resistant to the lethal effects of the phagocytes than were fast-growing magnesium-limited cells and carbon-limited cells (d = 0.05 h-1 and d = 0.5 h-1, respectively). the resistance of magnesium-limited cells to killing by cationic pro ...197897227
suppression of cellular responses in mice during trypanosoma cruzi infections.immunosuppression has been reported to occur in several protozoan parasitic infections. the significance of this suppression on host resistance or on parasite avoidance of immune destruction has not, however, been determined. in the present study two strains of mice that differ with respect to resistance to trypanosoma cruzi were examined during the course of infection for differences in expression of suppression of blastogenic responses to phytohemagglutinin and an antigen preparation of these ...197897228
adjuvant activity of synthetic 6-o-"mycoloyl"-n-acetylmuramyl-l-alanyl-d-isoglutamine and related compounds.adjuvant and antitumor activities of synthetic 6-o-"mycoloyl"-n-acetylmuramyl-l-alanyl-d-isoglutamine were examined. all the synthetic 6-o-corynomycoloyl-, 6-o-mocardomycoloyl-, and 6-o-mycoloyl-n-acetylmuramyl-l-alanyl-d-isoglutamine were active as adjuvants for cell-mediated immune responses. however, 6-o-mycoloyl-n-acetylmuramyl-l-alanyl-d-isoglutamine was less active as an adjuvant on circulating antibody formation. it was shown that pyrogenic activity of n-acetylmuramyldipeptide was reduced ...197897234
quantitative measurement of phagocytosis of neisseria gonorrhoeae by mouse peritoneal macrophages.the simultaneous labeling of gonococci with [6-3h]uracil and of mouse peritoneal macrophages with l-[u-14c]leucine permits a quantitative assessment of the association of gonococci with macrophages under various experimental conditions. colony-type t1 (piliated) gonococci associated more than t4 (nonpiliated) organisms at 4 degrees c, but at 37 degrees c the association of t4 gonococci with macrophages exceeded that for the t1 organisms. the association of t1 gonococci with macrophages could be ...197897235
demonstration of k88ac and k88ab antigens of escherichia coli by means of immunoelectrophoresis and immunodiffusion.five strains of escherichia coli were tested for the presence of the k88ac or k88ab antigens by immunoelectrophoresis and immunodiffusion. the k88ac antigen of 0a2 and sojka abbotstown gave an anodic line in the immunoelectrophoresis test and a line in immunodiffusion with homologous k88ac antisera. the k88ab antigens of 0g7, 0e68, and moon 263 also gave anodic lines in immunoelectrophoresis, and were detectable by immunodiffusions. the 0 groups of these strains were also demonstrated by immunoe ...197897237
is the solitary dark neuron a manifestation of postmortem trauma to the brain inadequately fixed by perfusion?dark neurons, classified as solitary because of their sparse occurrence, were discerned in the transitional zones between gray and white matter in various species of laboratory animals fixed by perfusion. these neurons, histologically indistinguishable from dark neurons in immersion fixed material, tended to develop when the saline perfusion was delayed or slow, the amount of the bouin fixative was excessive, or the autopsy was performed shortly after the perfusion. under these conditions, the w ...197897249
influence of type of antibiotic and length of antibiotic feeding period on performance and persistence of antibiotic resistant enteric bacteria in growing-finishing swine. 197897254
antimicrobial agents as preservatives in pharmaceutical and cosmetic products. agents as preservatives in eye-drops and contact lens solutions. 197897255
role of exotoxins in bacterial pathogenicity. 197897256
post-transcriptional modifications of the anticodon loop region: alterations in isoaccepting species of trna's during development in bacillus subtilis.structural similarities of trna's were compared using three sets of isoaccepting species that had previously been shown to undergo significant changes in chromatographic elution properties as a function of developmental stage in bacillus subtilis. comparisons of the structures of the trna's were based on the composition of their modified nucleosides, comparisons of oligonucleotide elution profiles from rpc-5 columns, and two-dimensional electrophoretic fingerprint analysis of oligonucleotides. t ...197897263
ultrastructural study of salmonella typhimurium treated with membrane-active agents: specific reaction dansylchloride with cell envelope components.amino groups of cell envelope proteins, lipids, and lipopolysaccharides cannot be labeled in intact cells of salmonella typhimurium g 30 by using 5-dimethylaminonaphthalene-1-sulfonylchloride incorporated in lecithin-cholesterol vesicles. however, application of membrane-interacting agents like tris(hydroxymethyl)aminomethane (tris)-hydrochloride, ethylenediaminetetraacetate (na salt) (edta), divalent cations, and sublethal doses of the cationic antibacterial agents polymyxin b and chlorhexidine ...197897268
evidence that spo0a mutations are recessive in spo0a-/spo0a+ merodiploid strains of bacillus subtilis.the spo0a locus contains two types of closely linked mutations that block sporulation at stage 0: spo0a mutations (the most pleiotropic of the stage 0 markers) and spo0c mutations. it was previously thought that spo0a mutations were dominant in merodiploids of bacillus subtilis, whereas spo0c mutations were recessive. we have shown that spo0a mutations were recessive when spo0a-/spo0a+ merodiploids were made in the genetic backgrounds of strains that were resistant to antibiotic produced by the ...197897278
mutarotation of hydrolysis products by different types of exo-cellulases from trichoderma viride.mutarotation of products from p-nitrophenyl beta-d-cellobioside and cellopentaitol by two different types of exo-cellulases from trichoderma viride was investigated. it was found that an exo-cellulase of glucosidase type produced from the former substrate d-glucose which was mutarotated in a downward direction, while another exo-cellulase of avicelase type produced from the latter substrate cellobiose which was mutarotated in an upward direction.197897279
amino acid sequence of beta-galactosidase. vii. isolation of the 24 cyanogen bromide peptides.all of the 24 cyanogen bromide peptides of beta-galactosidase have been isolated in pure form. of these 8 ranged in size from 2 to 5 residues and were purified by paper electrophoresis. the 16 large peptides, from 23 to 119 residues, were chromatographed at ph 5.0 on a carboxymethyl-cellulose column in 0.02 m ammonium acetate buffer containing 8 m urea. a number of peptides were obtained in pure from following sephadex g-50 or g-75 gel filtration. others were separated on sulfopropyl-sephadex or ...197897294
nitrate reductase activity of mycobacterium tuberculosis and mycobacterium bovis in the presence of electron donors.the activities of the nitrate reductase enzyme of mycobacterium tuberculosis, m. bovis, and of bcg were assayed with and without addition of electron donors. m. tuberculosis always reduced nitrate; m. bovis did so only in the presence of electron donors, and bcg did not show enzymatic activity.197897306
comparison of continuous and discontinuous counterimmunoelectrophoresis with immunodiffusion in identification of candida antibody using hs antigen.we have compared continuous counterimmunoelectrophoresis (ccie) and discontinuous counterimmunoelectrophoresis (dcie) with immunodiffusion (id) in the identification of candida albicans antibody using hs antigen. eighteen sera with a titer of 1/1 to 1/32 1/32 by ccie were titered by ccie and id. fewer were positive by ccie and id (13 of 18 and 9 of 18, respectively). furthermore, the titers were lower when measured by these two methods in comparison to dcie (4 of 18 and 3 of 18 sera had titers g ...197897308
aminoglycoside-inactivating enzymes in clinical isolates of streptococcus faecalis. an explanation for resistance to antibiotic synergism.clinical isolates of enterococci (streptococcus faecalis) with high-level resistance to both streptomycin and kanamycin (minimal inhibitory concentration >2,000 mug/ml), and resistant to synergism with penicillin and streptomycin or kanamycin were examined for aminoglycoside-inactivating enzymes. all of the 10 strains studied had streptomycin adenylyltransferase and neomycin phosphotransferase activities; the latter enzyme phosphorylated amikacin as well as its normal substrates, such as kanamyc ...197897312
entry of beta-n-oxalyl-l-alpha,beta-diaminopropionic acid, the lathyrus sativus neurotoxin into the central nervous system of the adult rat, chick and the rhesus monkey. 197897367
studies on the low-molecular weight glycoprotein gp-350: molecular and immunological heterogeneity. 197897368
lymphocyte responsiveness to pseudomonas aeruginosa in cystic fibrosis: relationship to status of pulmonary disease in sibling pairs.lymphocyte proliferative responses to pseudomonas aeruginosa and staphylococcus aureus were evaluated in six sibling pairs with cystic fibrosis. in each pair, one sibling had advanced clinical disease, whereas the other sibling was in good clinical condition. three in this latter group had no clinically apparent pseudomonas bronchitis. in all cases, the average responses to pseudomonas isolated from each sibling pair were lower in the sibling with advanced clinical disease. this difference was n ...197897373
meningitis caused by neisseria meningitidis type w-135. 197897374
[results of early nutrition of newborn infants with low birth weight. ii. effects of early nutrition on bilirubin metabolism of newborn infants with birth weights from 1501 to 2000 g]. 197897464
cerebral prostaglandin synthesis during the dietary and pathological stresses of essential fatty acid deficiency and experimental allergic encephalomyelitis.rats of the lewis strain were fed diets adequate or deficient in essential fatty acids (efa). at 70-80 days of age experimental allergic encephalomyelitis (eae) was induced using adjuvants containing either mycobacterium butyricum or mycobacterium tuberculois h37ra. when the former mycobacterium was used, the incidence of eae was greater in the efa-deficient than in efa-adequate controls; but when the rats challenged with m. tuberculosis, the incidence of the disease was the same in both dietary ...197897486
[isolation of penicillinase forming gonococci in munich]. 197897520
functional specialisation in the visual cortex of the rhesus monkey.anatomical and functional studies of the visual cortex of the rhesus monkey have shown that it is made up of a multiplicity of distinct areas. these seem to be functionally specialised to analyse different features of the visual environment.197897565
ultrastructural localization of cations in the rat pars distalis under various experimental conditions.modifications of the pyroantimonate technique were used to localize intracellular sites of bound cations in the pars distalis of normal and hypothyroid rats and in rats with increased levels of plasma calcium. in the normal animal, cations were localized within most intracellular organelles and sometimes on the membranes involved in exocytosis. the amount of bound cations within pituitary intracellular organelles was considerably augmented in rats injected intravenously with calcium chloride. ho ...197897571
lead poisoning in dogs. 197797605
biological influence of fat intake on mammary cancer and mammary tissue: experimental correlates. 197897651
relationship between the blood concentration of the drug and its cumulative effect: a pharmacokinetic analysis of the nephrotoxic action of gentamicin and streptomycin.the general principle of dependence of cumulative effects on drug concentration in the blood is proposed. the registered response is regarded as a result of the dual effect of drug blood level and duration of action. the corresponding experimental design consists in maintaining the serum concentration values at several definite levels and determining the response values for each of them. the constant serum level of the drug could be achieved by means of continuous infusion calculated according t ...197897679
blood and urinary catecholamine variations under the action of a high voltage electric field.white wistar male rats, weighing 150 +/- 20 g, adapted to the laboratory ambience during 12 days, were exposed to an electric field of 100 kv/m for 360 minutes in acute (once) or chronic experiment (12 days running). urinary (nanogram h-1) and blood catecholamines (microgram/100 ml) showed a significant increase as compared to the controls, adapted to the ambience but not exposed to an electric field. the most accentuated increase was that of adrenaline in the acute experiment. in the chronic ex ...197897688
the reinforcing property of ethanol in the rhesus monkey ii. some variables related to the maintenance of intravenous ethanol-reinforced responding. 197897716
stereotyped behavior and hyperthermia in dogs: correlation with the levels of amphetamine and p-hydroxyamphetamine in plasma and csf.a gas-chromatographic method for simultaneously measuring p-hydroxyamphetamine (poa) against amphetamine (a) in plasma and csf is presented. the time course of body temperature (tb), stereotyped behavior (st), and a and poa levels in plasma and csf were studied after administration of 0.6 and 1.5 mg/kg p.o. of a to dogs. stereotyped behavior reached maximal value 2.5 h after a, as did levels of a in csf. the a levels in csf decreased steadily in the following hours and simultaneously with the le ...197897724
tropical diseases. 197797727
radionuclide emission computed tomography of the body of laboratory animals.selective studies in the monkey and baboon demonstrate the normal physiologic distribution of 99mtc radiopharmaceuticals using single-photon emission computed tomography. the cases demonstrated the ability of the cleon transverse section brain imager tm to do emission computed tomography of various organs. this experience shows what can be expected when equipment for emission computed tomography of the body becomes available for patient studies.197897732
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