| regulating intensity using perceived exertion in spinal cord-injured participants. | to examine the validity of perception-based intensity regulation during handcycling exercise. | 2010 | 19952816 |
| [clinical analysis of adenoid cystic carcinoma of external auditory canal]. | to explore methods of treatment for adenoid cystic carcinoma of external auditory canal, and discuss the correlating factors that effect prognosis. | 2009 | 19954012 |
| [laryngeal function preserving surgery in hypopharyngeal carcinoma]. | to evaluate the preservation of laryngeal function hypopharyngeal cancer surgery clinical effectiveness and impact of prognostic factors. | 2009 | 19954017 |
| optimal lymph node dissection for t3-t4 lower rectal cancer, the so-called "high risk" group: the japanese experience. | | 2009 | 19954577 |
| extended surgical resection in stage iii non-small cell lung cancer. | stage iii includes a large variety of clinical situations from chest wall invasion together with intralobar lymph node metastasis to any size of a lung cancer in combination with mediastinal lymph node involvement (n2/n3). furthermore, the prognosis of patients with lymph node metastasis depends largely on the extent of the disease, which may range from micro-metastasis occasionally found during surgery to bulky and/or multilevel involvement of the mediastinum or extracapsular infiltration. not ... | 2010 | 19955797 |
| train of four responses in paretic limbs. | quadriplegic patients pose difficulty for neuromuscular monitoring owing to nonavailability of accessible normal muscle. it is known that train of four responses (t4/t1 ratio) was exaggerated in paretic limbs. however, no studies have quantified the exaggeration at different degrees of block. this study was undertaken to quantify the exaggeration of train of four responses in paretic limbs with increasing levels of block after the administration of neuromuscular blocking drugs. nine patients wit ... | 2009 | 19955896 |
| retrospective analysis of the treatment results for patients with squamous cell carcinoma of tonsil. | there has been no definitive randomized study to identify the optimal therapeutic regimen for treating squamous cell carcinoma of tonsil. the purpose of this study was to retrospectively evaluate the treatment outcome according to various combinations of surgery, radiation therapy and chemotherapy. | 2005 | 19956486 |
| the value of transmandibular approach to total maxillectomy in the management of t3-t4 carcinoma of the maxillary sinus. | surgical excision of the maxilla either as a primary procedure or after radiotherapy continues to play an important role in the management of carcinoma of the maxillary sinus. a majority of these cancers are seen in t3-t4 stage. recurrence at the infratemporal fossa has been recognized as a major cause of failure. although the importance of inclusion of the pterygopalatine fossa in the field of excision has been recognized, there is no uniform approach for en bloc removal of the pterygopalatine ... | 2010 | 19956963 |
| [endoscopic surgery using the low-temperature plasma radiofrequency for nasal inverted papilloma]. | to evaluate the effect of endoscopic surgery using the low-temperature plasma radiofrequency for nasal inverted papilloma. methods in a retrospective study, clinical data of 8 patients underwent endoscopic surgery were analyzed since july 2008. tumor stage according to krouse was t1:1, t2:6, t3:1, t4:0, respectively. t1 and t2 lesions were completed excised using the low-temperature plasma radiofrequency, t3 lesions were excised using microdebrider combined with plasma radiofrequency. | 2009 | 19957649 |
| [combination of trans-anal intersphincteric resection and trans-abdominal total mesorectal excision for anus-retained ultra-low rectal tumors]. | to study the combination of trans-anal intersphincteric resection and transabdominal total mesorectal excision for anus-retained ultra-low rectal tumors. | 2009 | 19957808 |
| [diagnostic significance and management principles of colorectal intraepithelial neoplasia]. | to discuss the significance of pathological diagnosis of colorectal intraepithelial neoplasia and its treatment principles. | 2009 | 19957809 |
| carbon dioxide-induced panic attacks and quantitative electroencephalogram in panic disorder patients. | the objective of the study was to investigate and compare the brain cortical activity, as indexed by quantitative electroencephalographic (qeeg) power, coherence and asymmetry measures, in panic disorder (pd) patients during an induced panic attack with a 35% co(2) challenge test and also in a resting condition. fifteen subjects with pd were randomly assigned to both 35% co(2) mixture and atmospheric compressed air, in a double-blind study design, with eeg being recorded for a 20-min period. dur ... | 2010 | 19958206 |
| cryoablation of stellate ganglia and atrial arrhythmia in ambulatory dogs with pacing-induced heart failure. | there is an association between autonomic nerve discharges and atrial arrhythmias (including bradycardia and tachycardia) in ambulatory dogs with pacing-induced heart failure (hf). | 2009 | 19959128 |
| [new tnm classification of malignant lung tumors 2009 from a pathology perspective]. | based on the iaslc multicenter data collected worldwide on 81495 patients diagnosed or registered with lung cancer between 1990 and 2000, the t, n, and m descriptors were analyzed and recommendations for changes in the seventh edition of the tnm classification were proposed on the basis of differences in survival. this new tnm classification replaces the old uicc classification and the staging system according to c. mountain 1997. the changes principally affect the t and m classifications. for t ... | 2009 | 19960300 |
| intraluminal versus infiltrating gallbladder carcinoma: clinical presentation, ultrasound and computed tomography. | to compare clinical presentation and ultrasound (us) and computed tomography (ct) sensitivity between intraluminal and infiltrating gallbladder carcinoma (gbca). | 2009 | 19960562 |
| thyroid function tests: a review. | in this paper, we review the tests that are executed to aid the diagnosis of thyroid dysfunction. thyroid function tests provide information at physiological, pathological and anatomical levels. along with history and physical examination they owe to many specific findings that are associated with thyroid functioning. so an attempt has been made to put forward a gist of thyroid function tests. serum tests of thyroid function are serum total thyroxine (t4), serum total triiodothyronin (t3), free ... | 2009 | 19961039 |
| chemiluminescent immunoassay of thyroxine enhanced by microchip electrophoresis. | a homogeneous chemiluminescent immunoassay of thyroxine (t4) enhanced by microchip electrophoresis separation has been developed. the method deployed the competitive immunoreaction of t4 and horseradish peroxidase (hrp)-labeled t4 (hrp-t4) with anti-t4 mouse monoclonal antibody (ab). hrp-t4 and the hrp-t4-ab complex were separated and quantified by using microchip electrophoresis (mce) with chemiluminescence (cl) detection. highly sensitive cl detection was achieved by means of hpr-catalyzed lum ... | 2010 | 19961826 |
| selenium affects the expression of gpx4 and catalase in the liver of chicken. | a total of 128 chickens (gallus gallus, broilers) were used to investigate the effect of organic selenium (se) in expression of catalase (cat) and phospholipid hydroperoxidase 4 (gpx4) genes. there were 4 replicates of 4 dietary treatments: t1 (basal diet with no added se), t2 (t1 with 0.15 ppm se added), t3 (t1 with 0.3 ppm se) and t4 (t1 with 3.0 ppm se). at 4th and 6th week, 2 chickens per replicate pen were sacrificed for whole blood and liver sample collections. samples were analyzed for to ... | 2010 | 19961950 |
| is duodenal invasion a relevant prognosticator in patients undergoing adjuvant chemoradiotherapy for distal common bile duct cancer? | to analyze the outcome of adjuvant chemoradiotherapy for patients with distal common bile duct (cbd) cancer who underwent curative surgery, and to identify the prognostic factors for these patients. | 2010 | 19962835 |
| single-molecule and fret fluorescence correlation spectroscopy analyses of phage dna packaging: colocalization of packaged phage t4 dna ends within the capsid. | linear dnas of any sequence can be packaged into empty viral procapsids by the phage t4 terminase with high efficiency in vitro. packaging substrates of 5 kbp and 50 kbp, terminated by energy transfer dye pairs, were constructed from plasmid and lambda phage dnas. nuclease and fluorescence correlation spectroscopy (fcs) assays showed that approximately 20% of the substrate dna was packaged and that the dna dye ends of the packaged dna were protected from nuclease digestion. upon packaging, both ... | 2010 | 19962991 |
| mutational analysis of the 5'-oh oligonucleotide phosphate acceptor site of t4 polynucleotide kinase. | t4 polynucleotide kinase/phosphatase (pnkp) exemplifies a family of bifunctional enzymes with 5'-kinase and 3'-phosphatase activities that function in nucleic acid repair. the n-terminal kinase domain belongs to the p-loop phosphotransferase superfamily. the kinase is distinguished by a tunnel-like active site with separate entrances on opposite sides of the protein for the ntp phosphate donor and a 5'-oh single-stranded oligonucleotide phosphate acceptor. here, we probed by mutagenesis the role ... | 2010 | 19966275 |
| the clinical significance of fat clearance lymph node harvest for invasive rectal adenocarcinoma following neoadjuvant therapy. | this study aimed to investigate the application of fat clearance in cases of rectal cancer after neoadjuvant chemoradiation. | 2009 | 19966611 |
| regional anaesthesia for caesarean section: a choice of three techniques. | over the last 20 years, there has been a large increase in the proportion of caesarean sections (brown and russell, 1995) which are performed under regional rather than general anaesthesia. a bilateral sensory block from the t4 dermatome (nipple level) to the sacral nerve roots (perineum) is necessary. | 2009 | 19966715 |
| selective inhibition of dna replicase assembly by a non-natural nucleotide: exploiting the structural diversity of atp-binding sites. | dna synthesis is catalyzed by an ensemble of proteins designated the replicase. the efficient assembly of this multiprotein complex is essential for the continuity of dna replication and is mediated by clamp-loading accessory proteins that use atp binding and hydrolysis to coordinate these events. as a consequence, the ability to selectively inhibit the activity of these accessory proteins provides a rational approach to regulate dna synthesis. toward this goal, we tested the ability of several ... | 2010 | 19994907 |
| [indication for bone scans in early breast cancer staging]. | evaluate the indication for bone scanning during staging of early breast cancer in the light of scientific evidence to assess the need to modify practices with scant effectiveness. | 2009 | 19995533 |
| serum cathepsin k and cystatin c concentration in patients with advanced non-small-cell lung cancer during chemotherapy. | a pathogenic implication of cathepsin k (cath k) and its inhibitor - cystatin c (cyst c) occur to be of growing importance in the mechanisms of tumor invasiveness in lung cancer. this study was conducted to investigate the prognostic role and the effects of chemotherapy on serum cath k and cyst c (elisa) in patients with advanced stage non-small cell lung cancer (nsclc). the study entered 40 patients (32 men) and 15 healthy volunteers (control group). peripheral blood samples were taken before a ... | 2009 | 19995705 |
| site-directed spin labeling of a genetically encoded unnatural amino acid. | the traditional site-directed spin labeling (sdsl) method, which utilizes cysteine residues and sulfhydryl-reactive nitroxide reagents, can be challenging for proteins that contain functionally important native cysteine residues or disulfide bonds. to make sdsl amenable to any protein, we introduce an orthogonal labeling strategy, i.e., one that does not rely on any of the functional groups found in the common 20 amino acids. in this method, the genetically encoded unnatural amino acid p-acetyl- ... | 2009 | 19995976 |
| efficacy of transsphenoidal surgery on endocrinological status and serum chemistry parameters in dogs with cushing's disease. | postoperative changes in endocrinological status and serum chemistry during the 4 years after transsphenoidal surgery (tss) in 25 dogs with cushing's disease were investigated in a prospective study. in all 25 dogs, cushing's disease was diagnosed from resected pituitary tissues as a corticotroph adenoma in the anterior lobe of the pituitary. prior to tss, all 25 dogs showed hypercortisolemia. after tss, the acth stimulation test showed continued low serum cortisol concentrations in 21 dogs (84% ... | 2010 | 19996557 |
| urinary diversion after cystectomy for bladder cancer: a population-based study in sweden. | to investigate the type of urinary diversion performed after cystectomy in patients with muscle-invasive bladder cancer in sweden, using data from a population-based national register. | 2010 | 20001606 |
| clinical significance of macroscopic completeness of mesorectal resection in rectal cancer. | local recurrence after resection of rectal cancer is usually regarded as being due to a 'failure' of surgery. the completeness of resection of the mesorectum has been proposed as an indicator of the 'quality' of the resection. we determined the prognostic value of macroscopic evaluation of rectal cancer resection specimens and the circumferential resection margin (crm) after curative surgery. | 2011 | 20002696 |
| thyroid function abnormalities among first-degree relatives of iranian congenital hypothyroidism neonates. | congenital hypothyroidism (ch) is a relatively common metabolic disease in neonates. until recent years the disorder was usually regarded as occurring in a sporadic manner. over the past few years, however, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. the aim of the present study was to evaluate abnormality of thyroid function tests in first-degree relatives of ch neonates and compared this to the normal population. | 2010 | 20003140 |
| tumor volume reduction rate measured by magnetic resonance volumetry correlated with pathologic tumor response of preoperative chemoradiotherapy for rectal cancer. | to determine whether the tumor volume reduction rate (tvrr) measured using three-dimensional region-of-interest magnetic resonance volumetry correlates with the pathologic tumor response after preoperative chemoradiotherapy (crt) for locally advanced rectal cancer. | 2010 | 20004532 |
| prenatal thyroxine treatment disparately affects peripheral and amygdala thyroid hormone levels. | a prenatal hypothyroid state is associated with behavioral abnormalities in adulthood. wistar kyoto (wky) rats exhibit hypothyroidism and increased depressive and anxiety-like behaviors. thus, the wky could illuminate the mechanisms by which the reversal of developmental hypothyroidism in humans and animals results in adult behavioral improvement. we examined the outcome of maternal thyroxine (t4) treatment on thyroid hormone-regulated functions and adult behavior of the wky offspring. pregnant ... | 2010 | 20005050 |
| predictors of locoregional recurrence in early stage oral cavity cancer with free surgical margins. | locoregional recurrence in patients with early stage oral cavity squamous cell carcinoma (esoscc) after surgery remains a problem and can affect their survival. we sought to identify new high-risk factors in these patients, who need further adjuvant therapy. we retrospectively reviewed records for 148 patients who underwent surgery for esoscc between 2002 and 2006 with negative surgical margins. the primary endpoint was locoregional recurrence. recurrence-free survival (rfs) and overall survival ... | 2010 | 20005769 |
| spinal epidural hematoma following epidural catheter removal in a paraplegic patient. | spinal epidural hematoma is a rare and devastating complication of epidural catheter removal in an anticoagulated patient. the diagnosis could be quite challenging, especially in patients with preexisting neurological deficits. a 35-year-old patient with remote spinal cord injury and t4 level paraplegia developed a spinal epidural hematoma on the 7th postoperative day. the hematoma developed after epidural catheter removal with concurrent administration of unfractionated heparin. | 2009 | 20006262 |
| robotic radical cystectomy for bladder cancer: surgical and pathological outcomes in 100 consecutive cases. | radical cystectomy remains the most effective treatment for patients with localized, invasive bladder cancer and recurrent noninvasive disease. recently some surgeons have begun to describe outcomes associated with less invasive surgical approaches to this disease such as laparoscopic or robotic assisted techniques. we report our maturing experience with 100 consecutive cases of robotic assisted laparoscopic radical cystectomy with regard to perioperative results, pathological outcomes and surgi ... | 2010 | 20006884 |
| use of dietary thyroxine as an alternate molting procedure in spent turkey breeder hens. | in the turkey industry, molting is traditionally achieved by reducing photoperiod and withdrawing feed and water for several days. although it is the most effective method, this practice is discouraged in canada and alternative strategies need to be established. thyroid hormone levels naturally change during molt, and dietary thyroxine (t4) supplementation was previously shown to induce molt in chickens. this study aimed at evaluating the effectiveness of supplemental dietary t4 in inducing molt ... | 2010 | 20008807 |
| sensibility following innervated free tram flap for breast reconstruction: part ii. innervation improves patient-rated quality of life. | restoring sensory innervation may be a useful adjunct in free flap head and neck reconstruction but, as yet, has not been shown to improve outcomes of breast reconstruction. the authors' previous study demonstrated objectively improved sensation in a group of innervated transverse rectus abdominis musculocutaneous (tram) flap breast reconstruction patients relative to noninnervated flaps. this study compared patient-rated outcomes of free tram breast reconstruction in innervated versus noninnerv ... | 2009 | 20009826 |
| patients with low rectal cancer treated by abdominoperineal excision have worse tumors and higher involved margin rates compared with patients treated by anterior resection. | patients with low rectal cancer have worse outcomes compared to those with upper rectal cancer. reports suggest that low anterior resection may be oncologically superior to abdominoperineal excision, although no good evidence exists to support this. we looked at a recent series of patients with low rectal cancer to explore some of the issues. | 2010 | 20010351 |
| biomechanical characteristics of different regions of the human spine: an in vitro study on multilevel spinal segments. | study design.: an in vitro study on human multilevel spinal segments. objective.: to determine the differences in biomechanical characteristics between 4 separate regions of the human spine and to provide quantitative information is derived on the range of motion (rom), neutral zone (nz), neutral zone stiffness (nzstiff), and flexibility (flex). summary of background data.: limited literature is available about the biomechanical behavior of different regions of the human spine, in particular wit ... | 2009 | 20010393 |
| thoracic pedicle subtraction osteotomy for fixed sagittal spinal deformity. | study design.: a retrospective clinical study. objective.: to find the corrective capacity of a thoracic pedicle subtraction osteotomy (pso), determine if segmental correction is dependent on level, and to compute the impact of thoracic pso on regional and global spinal balance. summary of background data.: pso is a technique popularized in the lumbar spine primarily for the correction of fixed sagittal imbalance. despite several studies describing the clinical and radiographic outcome of lumbar ... | 2009 | 20010396 |
| schmorl's nodes distribution in the human spine and its possible etiology. | although schmorl's nodes (sns) are a common phenomenon in the normal adult population, their prevalence is controversial and etiology still debatable. the objective was to establish the spatial distribution of sns along the spine in order to reveal its pathophysiology. in this study, we examined 240 human skeleton spines (t4-l5) (from the hamann-todd osteological collection) for the presence and location of sns. to determine the exact position of sns, each vertebral body surface was divided into ... | 2010 | 20012754 |
| diabetic ketoacidosis, thyroiditis and alopecia areata in a child with down syndrome. | a 10-year-old girl with down syndrome and alopecia areata was admitted with severe ketoacidosis. she had high blood glucose level: 615 mg/dl and her hbalc level was 13.3 %. after the control of ketoacidosis and reduction of the plasma glucose level, we found low free t4 level and high tsh levels. thyroid peroxidase antibodies titer was 1383 iu/ml and both gliadin and endomysial antibodies were negative. this was the first report of a child with down syndrome showing type 1 diabetes combined with ... | 2009 | 20012788 |
| acanthamoeba strains show reduced temperature tolerance after long-term axenic culture. | acanthamoeba is a genus of free-living organisms that can be found in various habitats. we investigated the physiological characteristics of 15 acanthamoeba isolates, representing five genotypes (t4, t5, t6, t7, and t11) of both clinical and nonclinical origins. moreover, in order to evaluate possible alterations from long-term culture, old and fresh isolates were included, and results were compared to a previous study. we found that there is no significant difference in physiological characteri ... | 2010 | 20012991 |
| low cortisol levels in active juvenile idiopathic arthritis. | the aim of our study was to evaluate the neuroendocrine system in patients with juvenile idiopathic arthritis (jia) regarding the activity of disease. twenty-one jia patients (mean age +/- standard deviation 10.5 +/- 4.1 years) were included. none of the patients was taking steroids or antitumor necrosis factor-alpha therapy during this study. ten healthy volunteers and ten volunteers with upper respiratory tract infection composed the control groups. furthermore, ten of the 21 jia patients were ... | 2010 | 20013015 |
| postoperative laryngoscopy in thyroid surgery: proper timing to detect recurrent laryngeal nerve injury. | there is currently a lack of consensus to support the proper timing for postoperative laryngoscopy that is reliable to diagnose recurrent laryngeal nerve palsy (rlnp) after thyroid surgery. the purpose of this study was to investigate the impact of different time intervals of fiber-optic nasolaryngoscopy (fnl) on the diagnosis of rlnp. | 2010 | 20013128 |
| comparison of equipotent doses of ropivacaine-fentanyl and bupivacaine-fentanyl in spinal anaesthesia for lower abdominal surgery. | the aim of this randomised, double-blind study was to compare equipotent doses of plain ropivacaine and bupivacaine (19.5 mg and 13 mg respectively), both with fentanyl 20 microg, for spinal anaesthesia in lower abdominal surgery. after written informed consent had been obtained, 52 asa i to ii male patients scheduled for lower abdominal surgery were randomly assigned to receive intrathecal plain ropivacaine 19.5 mg with fentanyl 20 microg (group r, n =26) or plain bupivacaine 13 mg with fentany ... | 2009 | 20014598 |
| breast cancer with non-inflammatory skin involvement: current data on an underreported entity and its problematic classification. | we evaluated 166 breast cancer cases with non-inflammatory skin involvement (nisi), which were classified in the tnm classification as t4b. the distribution of tumour sizes and stages was: < or =3 cm:24.1%, 3.1-5 cm:21.7%, 5.1-10 cm:33.1%, >10 cm:21.1%; stages:i/ii:21.0%, iii:43.4%, iv:35.6%. to assess the impact of nisi on axillary lymph node involvement (alni), we analyzed a sub-group of 50 patients with tumours < or =5 cm and compared them with a matched control group. nisi was found to be as ... | 2010 | 20015652 |
| impact of preepiglottic space tumor involvement on concurrent chemoradiation therapy. | the aim of the study was to determine the prognostic impact of preepiglottic space (pes) involvement on local failure after concurrent chemoradiation therapy for squamous cell carcinoma. | 2010 | 20015743 |
| does recombinant human thyrotropin-stimulated positron emission tomography with [18f]fluoro-2-deoxy-d-glucose improve detection of recurrence of well-differentiated thyroid carcinoma in patients with low serum thyroglobulin? | thyrotropin (tsh) stimulates thyrocyte metabolism, glucose transport, and glycolysis. the interest in using recombinant human tsh (rhtsh) stimulation of fluoro-2-deoxy-d-glucose (fdg) with positron emission tomography (pet) has been shown, but mainly for patients with high serum thyroglobulin (tg) concentration. we evaluated the use of rhtsh-stimulated pet-fdg in patients with low serum tg concentration. | 2010 | 20017617 |
| characterization of spinal afferent neurons projecting to different chambers of the rat heart. | the pattern of distribution of spinal afferent neurons (among dorsal root ganglia-drgs) that project to anatomically and functionally different chambers of the rat heart, as well as their morphological and neurochemical characteristics were investigated. retrograde tracing using a patch loaded with fast blue (fb) was applied to all four chambers of the rat heart and labeled cardiac spinal afferents were characterized by using three neurochemical markers. the majority of cardiac projecting neuron ... | 2010 | 20018227 |
| dominant mycobacterium tuberculosis lineages in elderly patients born in norway. | during the previous century norway had a high incidence of tuberculosis, but no molecular epidemiological studies could be performed and these previously epidemic strains have been disappearing during the last decades. currently, tuberculosis among native norwegians is in the elimination phase, and it is still not known what type of m. tuberculosis was so efficiently controlled during the second half of the 20th century. however, many elderly norwegian-born people still develop tb that cannot be ... | 2009 | 20020043 |
| clinical and biomaterial evaluation of a new condensed dual-function extracorporeal circuit in reoperation for coronary artery bypass surgery. | this prospective, randomized study compared the clinical performance of three types of circuits: a newly introduced, fully-coated, interchangeable open-closed circuit with a dual configuration (hard shell with a bypass shunt), reduced length, and reduced prime of less than 800 cc (condecc); a completely coated circuit (ecc); and a similar uncoated, open circuit with standard length and prime (cont). | 2009 | 20020412 |
| 9 years follow-up of a patient with pituitary form of resistance to thyroid hormones (prth): comparison of two treatment periods of d-thyroxine and triiodothyroacetic acid (triac). | patients with pituitary resistance to thyroid hormones (prth) exhibit features of hyperthyroidism due to normal sensitivity to thyroid hormones in some of the peripheral tissues. there is a lack of information in the literature on the long-term follow-up and treatment of patients with prth. here, we present long-term (9 years) clinical and biochemical follow-up of a patient with prth under the treatment of d-t4 initially (for 1.5 years) followed by triac for 5.5 years. an 11.5 year-old girl was ... | 2009 | 20020587 |
| [combined surgical interventions for advanced thyroid carcinoma]. | an analysis of specificities of 141 combined operations for advanced (t4) papillary, follicular and medullary thyroid carcinoma has shown that such operations proved to be necessary in 5.4% out of 2606 patients operated for carcinoma of the thyroid gland (ctg). in most cases these operations were of organ-sparing character. in 10.5% of the patients circular resections of organs of the respiratory and digestive systems were fulfilled on the neck and head. complete removal of the tumor was obtaine ... | 2009 | 20020626 |
| carbofuran-induced endocrine disruption in adult male rats. | the objective of this investigation was to determine the acute toxic effects of the carbamate insecticide carbofuran on the levels of endocrine hormones in the serum of male sprague-dawley rats. using chemiluminescent immunoassay, the hormones determined were progesterone, cortisol, estradiol, testosterone, triidothyronine (t3), total thyroxine (total t4), and non-protein-bound thyroxine (free t4). rats exposed to an acute dose of carbofuran (1.5 mg/kg, s.c.) showed the onset of cholinergic sign ... | 2004 | 20021136 |
| perioperative monitoring of thromboelastograph on hemostasis and therapy for cyanotic infants undergoing complex cardiac surgery. | this study investigated features and treatments of perioperative coagulopathies in cyanotic infants with complex congenital heart disease (cchd). thirty-six infants with cyanotic cchd were involved and divided into two groups: in group h (n = 20), hematocrit (hct) > 54%, and in group l (n = 16), hct < 54%. blood was sampled at anesthesia induction (t1), rewarming to 36 degrees c (t2), after heparin neutralization (t3), and 4 h after operation (t4). the hemostatic changes were evaluated by thromb ... | 2009 | 20021469 |
| [diagnostic value of double contrast-enhanced ultrasonography in preoperative staging of gastric cancer]. | to evaluate the clinical value of double contrast-enhanced ultrasonography using oral and intravenous contrast agents in preoperative staging of gastric cancer. | 2009 | 20021869 |
| [surgical treatment for bronchioloalveolar carcinoma with ipsilateral intrapulmonary metastatic nodules]. | the staging and treatment of bronchioloalveolar carcinoma (bac) with pulmonary metastasis are still controversial. this study aimed at evaluating the current staging of bac with ipsilateral intrapulmonary metastatic nodules and the therapeutic effectiveness of surgical resection. | 2009 | 20021955 |
| surgical treatment of synchronous multiple lung cancer located in a different lobe or lung: high survival in node-negative subgroup. | the international association for study of lung cancer staging committee proposes for the next revision of tnm (tumour, nodes, metastases) classification that additional nodules in a different lobe of the ipsilateral lung moves from an m1 designation to t4, while additional nodule(s) in the contralateral lung should be classified as m1a, because of poorer survival. we analysed the survival after surgery of patients presenting with synchronous lung cancers located in a different lobe or lung. | 2010 | 20022516 |
| transfer of a phage t4 gene into enterobacteriaceae, determined at the single-cell level. | the transfer range of phage genes was investigated at the single-cell level by using an in situ dna amplification technique. after absorption of phages, a phage t4 gene was maintained in the genomes of non-plaque-forming bacteria at frequencies of 10(-2) gene copies per cell. the gene transfer decreased the mutation frequencies in nonhost recipients. | 2010 | 20023087 |
| influence of persistent thyroxine reduction on spermatogenesis in rats neonatally exposed to 2,2',4,4',5,5'-hexa-chlorobiphenyl. | the aim of the present study is to determine the long-term testicular effects of neonatal exposure to pcb153. | 2010 | 20025066 |
| thoracic myelopathy secondary to intradural extramedullary bronchogenic cyst. | to report a case of thoracic myelopathy secondary to intradural extramedullary bronchogenic cyst. | 2009 | 20025159 |
| clinical performance and biocompatibility of hyaluronan-based heparin-bonded extracorporeal circuits in different risk cohorts. | this prospective randomized study compares novel hyaluronan-based heparin-bonded circuits vs. uncoated controls across euroscore patient risk strata including biomaterial evaluation. over a two-year period, 90 patients undergoing coronary artery bypass grafting were prospectively randomized to one of the two perfusion protocols: group 1 was treated with hyaluronan-based heparin-bonded preconnected circuits (vision hfo-gbs, gish, ca, usa) and group 2 with identical uncoated controls. each group w ... | 2010 | 20026488 |
| endoscopic resection of sinonasal cancers with and without craniotomy: oncologic results. | to evaluate the oncologic outcomes of patients with sinonasal cancer treated with endoscopic resection. | 2009 | 20026819 |
| colon cancer and low lymph node count: who is to blame? | to identify the factors that contribute to the disparity in the number of lymph nodes examined for curative colon cancer resections. | 2009 | 20026828 |
| leptin and ghrelin concentrations and weight loss in parkinson's disease. | to investigate the role of leptin, ghrelin, gh and igf-1 in energy balance disturbances in parkinson's disease (pd). | 2010 | 20028343 |
| treatment results of adults and children with medulloblastoma nci, cairo university experience. | to evaluate treatment outcome and prognostic factors of adults and pediatric medulloblastoma patients treated by adjuvant postoperative craniospinal irradiation (csi) and chemotherapy. | 2008 | 20029474 |
| phenotypic plasticity in number of glomeruli and sensory innervation of the antennal lobe in leaf-cutting ant workers (a. vollenweideri). | in the leaf-cutting ant atta vollenweideri, the worker caste exhibits a pronounced size-polymorphism, and division of labor is dependent on worker size (alloethism). behavior is largely guided by olfaction, and the olfactory system is highly developed. in a recent study, two different phenotypes of the antennal lobe of atta vollenweideri workers were found: mg- and rg-phenotype (with/without a macroglomerulus). here we ask whether the glomerular numbers are related to worker size. we found that ... | 2010 | 20029932 |
| [experiment research of jiajian yunvjian granules on hyperthyroidism graves]. | to investigate the effects and the related mechanisms of jiajian yunujian (jjynj) granules, which were made from traditional chinese medicinal prescription, on hyperthyroidism graves. | 2009 | 20030091 |
| [clinical significance of apolipoprotein b-48 (apob-48) in patients with thyroid disease]. | apolipoprotein b-48 (apob-48) is a constituent of chylomicrons and chylomicron remnants, and its serum concentration is thought to be one of the risk factors for atherosclerosis. clinically overt hypothyroidism (oh) has been associated with accelerated and premature coronary atherosclerosis. in the current study, we measured the serum apob-48 concentration in patients with hyperthyroidism and hypothyroidism. we also evaluated the correlations between serum apob-48 and thyroid hormones, from whic ... | 2009 | 20030174 |
| optimal placement of a superior vena cava cannula in minimally invasive robot-assisted cardiac surgery. | minimally invasive robot-assisted cardiac surgery is generally performed nowadays. to avoid the interference of a superior vena cava (svc) cannula during surgery, it should be inserted before the operation. the position of this cannula is very important because it can cause poor venous drainage during operation. the proper position of the svc cannula was investigated in the present study. | 2010 | 20032562 |
| lipid profiles in the untreated patients with hashimoto thyroiditis and the effects of thyroxine treatment on subclinical hypothyroidism with hashimoto thyroiditis. | to evaluate the prevalence of dyslipidemia in the population of hashimoto thyroiditis, we reviewed medical records on the consecutive 1181 cases with adult hashimoto thyroiditis and 830 cases were adopted for the study. first, the serum tsh level increased and serum free t4 level decreased, slightly but significantly, with increasing age. there were significant positive correlations between serum tsh levels and lipid parameters such as total cholesterol (tc), triglyceride (tg), hdl-cholesterol ( ... | 2010 | 20032565 |
| optimum lymphadenectomy for esophageal cancer. | using worldwide esophageal cancer collaboration data, we sought to (1) characterize the relationship between survival and extent of lymphadenectomy, and (2) from this, define optimum lymphadenectomy. | 2010 | 20032718 |
| concurrent chemoradiation followed by adjuvant chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma in korea. | concomitant approach using cisplatin and 5-fluorouracil (5-fu) has shown an excellent local control rate and significantly reduced distant metastasis in patients with locally advanced nasopharyngeal carcinoma (npc). however, optimal schedule and dosing of chemotherapy still need to be developed to reduce distant metastasis. this retrospective study was conducted to evaluate the efficacy, toxicity, and tolerability of a concurrent chemoradiation therapy (ccrt) regimen using cisplatin and 5-fu fol ... | 2010 | 20033411 |
| radiation therapy for feline cutaneous squamous cell carcinoma using a hypofractionated protocol. | the objective of this paper was to evaluate the efficacy of a hypofractionated radiation protocol for feline facial squamous cell carcinoma (scc). twenty-five histologically confirmed sccs in 15 cats were treated with four fractions of 7.6-10gy each, with 1 week intervals. the equipment used was a linear accelerator clinac 2100 delivering electron beam of 4 or 6mev, and a bolus of 5 or 10mm was used in all lesions. of the lesions, 44% were staged as t4, 16% as t3, 8% as t2 and 32% as t1. of the ... | 2010 | 20034827 |
| comparison of video-assisted thyroidectomy and traditional thyroidectomy for the treatment of papillary thyroid carcinoma. | there is concern regarding the oncological effectiveness of minimally invasive video-assisted thyroidectomy (vat) for thyroid carcinoma. this study compared the surgical results of vat and traditional thyroidectomy in patients with small papillary thyroid carcinomas (ptc). | 2010 | 20035348 |
| video. endoscopic minimally invasive thyroidectomy: first clinical experience. | since theodor kocher reduced the mortality rate of thyroidectomy from the 40% reported by billroth to 0.2% in 1895, a collar incision with open removal of the thyroid gland is the standard procedure. in the past decade, efforts were made to reduce incision size and surgical access trauma by the use of endoscopic techniques. a first attempt was replacement of the central "kocher incision" with lateral neck incisions and endoscopic removal of a thyroid lobe by hüscher on 8 july 1996. this lateral ... | 2010 | 20035350 |
| 3d postural balance with regard to gravity line: an evaluation in the transversal plane on 93 patients and 23 asymptomatic volunteers. | relevance of posture assessment has been reported in case of spine disorders. this study explores the interest in quantifying posture using 3d reconstruction from biplanar x-rays in free standing position and a force plate. 93 patients consulting for spine disorders were divided ('3d deformity', 'sagittal imbalance' and 'mild deformity') and compared with 23 asymptomatic volunteers. registration of the gravity line (gl) in reconstruction yielded transversal position of the center of acoustic mea ... | 2010 | 20035359 |
| mesotrypsin promotes malignant growth of breast cancer cells through shedding of cd109. | serine proteases have been implicated in many stages of cancer development, facilitating tumor cell growth, invasion, and metastasis, and naturally occurring serine protease inhibitors have shown promise as potential anticancer therapeutics. optimal design of inhibitors as potential therapeutics requires the identification of the specific serine proteases involved in disease progression and the functional targets responsible for the tumor-promoting properties. here, we use the hmt-3522 breast ca ... | 2010 | 20035377 |
| [the il-6 and cox-2 expression related to sensitivity of chemoradiotherapy and prognosis in esophageal carcinoma]. | chemoradiation therapy (crt) for esophageal cancer induces inflammatory responses within tumor tissues. inflammatory cells infiltrated into the tumor tissues may modulate the crt responses via inflammation-related molecules such as il-6 or cox-2. in the present study, we investigated a relationship between il-6/cox-2 expression and crt responses for esophageal cancer. a surgical resection following crt was performed, and the specimens from the patients with ct3/t4 esophageal squamous cell examin ... | 2009 | 20037297 |
| [evaluation of hepatic resection for synchronous liver metastasis from gastric cancer]. | to evaluate the effect of hepatic resection for synchronous liver metastasis from gastric cancer, the clinicopathological factors of gastric cancer, the size and number of liver metastasis and surgical procedures for liver metastasis were studied. between 1977 and 2006, a total of 49 patients (38 men and 11 women) underwent hepatic resections and gastrectomy. the median age was 70 years old (range 41-81). as for pathological type, intestinal/diffuse was 26/23. t1/t2/t3/t4 was 4/14/23/8. for lymp ... | 2009 | 20037309 |
| [our experiences of preoperative chemoradiotherapy for rectal cancer with invasion to adjacent organs]. | we reviewed clinical records of 10 cases with preoperative chemoradiotherapy to evaluate the clinical effectiveness of the chemoradiotherapy for t4 rectal cancer. the preoperative radiation therapy consisted of 40-50 gy delivered in fractions of 1.8-2.0 gy per day for five days per week. a treatment of 5-fluorouracil (500 mg/body) per day intravenously, or oral uft-e (300 mg/m2) with l-leucovorin (75 mg/body) per day, or oral s-1 (80 mg/m2) per day for five days per week, was given during radiot ... | 2009 | 20037350 |
| [radiofrequency ablation combined with transcatheter arterial chemoembolization for the local recurrent tumor after resection of the adrenal metastasis from hepatocellular carcinoma--a case report]. | we report a case of local recurrent tumor after a resection of right adrenal metastasis from hepatocellular carcinoma successfully treated with radiofrequency ablation combined with transcatheter arterial chemoembolization. the case is a man in his 80s who had a curative surgical resection and microwave coagulation therapy (mct) for multiple hepatocellular carcinomas in february 2003. the lesions were judged to be t4, n0, m0 and stage iv,then, he was treated as an outpatient on a regular schedul ... | 2009 | 20037426 |
| effectiveness of radiation synovectomy with samarium-153 particulate hydroxyapatite in rheumatoid arthritis patients with knee synovitis: a controlled randomized double-blind trial. | the aim of the present study was to investigate the effectiveness of samarium(153)-particulate hydroxyapatite radiation synovectomy in rheumatoid arthritis patients with chronic knee synovitis. | 2009 | 20037706 |
| evaluation of thyroid hormone levels and somatomedin-c (igf-1) in patients with chronic obstructive pulmonary disease (copd) and relation with the severity of the disease. | chronic obstructive pulmonary disease (copd) has recently become a significant cause of mortality and morbidity. in the present study, we aimed to investigate the relationship between the severity of the disease and levels of serum thyroid hormones and somatomedin-c [insulin-like growth factor (igf-1)]. sixty one copd cases (group 1) were enrolled. control group (group 2) consisted of 20 healthy individuals. blood samples were obtained for the analysis of arterial blood gases and hormone levels ... | 2009 | 20037851 |
| [prophylactic irradiation of cervical lymph nodes for stage-n0 nasopharyngeal carcinoma]. | it is controversial for the irradiation level and dose of the regional prevention for naspharyngeal cancer (npc) with one or both cervical lymph node-negative neck. the study was to analyze the proophylactic irradiation of cervical lymph nodes for stage -n0 npc patients. | 2010 | 20038321 |
| using the rate of respiration to monitor events in the infection of escherichia coli cultures by bacteriophage t4. | the growing interest in applications of bacteriophages creates a need for improvements in the production processes. continuous monitoring of the phage production is an essential aspect of any control strategy and, at present, there is no completely satisfactory option. the approach presented here uses ir-spectrometry to continuously measure the rate of respiration (co(2) released) of escherichia coli infected by phage t4 at various multiplicities of infection (moi). within the trends in these da ... | 2010 | 20039436 |
| [salinomycin and semduramicin in different concentrations on the broilers eimeriosis control]. | this study aimed to investigate the association of salinomycin and semduramicin, in different doses, against controlled mixed infection of eimeria acervulina, e. maxima and e. tenella in broiler chickens. eight hundred birds were divided into 5 groups (t1: not medicated feed; t2: 30 ppm of salinomycin and 12.5 ppm of semduramicin; t3: 30 ppm of salinomycin and 15 ppm of semduramicin; t4: 40 ppm of salinomycin and 12,5 ppm of semduramicin and t5: 40 ppm of salinomycin and 15 ppm of semduramicin) ... | 2009 | 20040210 |
| short-term in-home intervention reduces depressive symptoms in early head start latina mothers of infants and toddlers. | depressive symptoms may compromise the ability of low-income latina mothers with limited english language proficiency to parent their infants or toddlers. eighty early head start latina mothers with limited english language proficiency were randomized to an advanced practice nurse-delivered, culturally tailored, in-home psychotherapy intervention, or to usual care. repeated measures regression analysis showed a significantly greater decrease in depressive symptoms for intervention mothers compar ... | 2010 | 20043296 |
| development of tefs for pcb congeners by using an alternative biomarker--thyroid hormone levels. | polychlorinated biphenyls (pcbs) are ubiquitous toxic contaminants. health risk assessment for this class of chemicals is complex: the current toxic equivalency factor (tef) method covers dioxin-like (dl-) pcbs, dibenzofurans, and dioxins, but excludes non-dl-pcbs. to address this deficiency, we evaluated published data for several pcb congeners to determine common biomarkers of effect. we found that the most sensitive biomarkers for dl-non-ortho-pcb 77 and pcb 126 are liver enzyme (e.g., ethoxy ... | 2010 | 20043972 |
| is elective irradiation to the lower neck necessary for n0 nasopharyngeal carcinoma? | to summarize our experience and treatment results in lymph node-negative nasopharyngeal carcinoma treated in a single institution. | 2010 | 20044215 |
| increased incidence of papillary thyroid cancer detection among thyroidectomies in greece between 1991 and 2006. | to examine existing evidence, trends and possible factors that may have affected the incidence of papillary thyroid cancer (ptc) among patients undergoing thyroidectomies in an iodine-sufficient population of greece. | 2009 | 20044632 |
| thyroid hormone prevents cognitive deficit in a mouse model of alzheimer's disease. | this study aimed to examine the feasibility of using thyroid hormone (th) as a therapeutic agent for alzheimer's disease (ad). mice were injected intra-hippocampally aggregated amyloid beta-peptide (abeta) to produce ad animal model. intraperitoneal administration of l-thyroxine (l-t4) into abeta-induced ad model mice prevented their cognitive impairment and improved their memory function. the mechanisms of l-t4 treating ad might be associated with regulating cholinergic function, protecting the ... | 2010 | 20045708 |
| the enzymatic activity of type 1 iodothyronine deiodinase (d1) is low in liver hemangioma: a preliminary study. | type 1 iodothyronine deiodinase (d1) is a crucial enzyme which converts the prohormone thyroxine (t4) into active tri-iodothyronine (t3). there has been strong evidence that the metabolism of thyroid hormones is disturbed in some neoplastic tissues such as thyroid, renal, and breast cancer. however, there are few available data about d1 enzyme activity in benign tumors such as hemangioma, which is the most common primary liver tumor. hence this study aimed to determine the enzymatic activity of ... | 2010 | 20049650 |
| translational research in cancer genetics: the road less traveled. | gene discoveries in cancer have the potential for clinical and public health applications. to take advantage of such discoveries, a translational research agenda is needed to take discoveries from the bench to population health impact. to assess the current status of translational research in cancer genetics, we analyzed the extramural grant portfolio of the national cancer institute (nci) from fiscal year 2007, as well as the cancer genetic research articles published in 2007. we classified bot ... | 2011 | 20051673 |
| post-treatment evaluation of a magnetic activator device in class ii high-angle malocclusions. | summary: the purpose of this study was to evaluate changes in dentofacial growth before, during, and after use of a magnetic activator device (mad) ii in high-angle class ii division 1 patients. lateral cephalometric and hand-wrist radiographs of 10 patients (six girls and four boys) with an average chronological age of 10 years 5 months were obtained at the beginning of the observation period (t1, 9.5 months), beginning of mad ii application (t2), at the end of the treatment (t3), and approxima ... | 2010 | 20053717 |
| spinal growth and progression of adolescent idiopathic scoliosis. | the spinal growth in scoliotic segments (t4-l4) of 110 girls with untreated idiopathic scoliosis was measured from two successive radiographs taken at a mean interval of 1.1 years. at the first visit the mean age of the patients was 14 years (range 11-16 years), the mean magnitude of the major curves 24 degrees (range 9 degrees-38 degrees) and that of the minor curves 14 degrees (range 2 degrees-38 degrees). spinal growth was most rapid at the age of 11-12 years. the progression of the curves (m ... | 1993 | 20054924 |
| frequency of hypothyroidism in patients of beta-thalassaemia. | to determine the frequency of hypothyroidism in patients suffering from homozygous beta-thalassaemia. | 2010 | 20055273 |
| exploration of composted cereal waste and poultry manure for soil restoration. | poultry manure and fungal consortium developed by including fungi of genus aspergillus, trichoderma and phanerochaete were evaluated separately to degrade high silica paddy straw. the quality evaluation of composted organic wastes after two months of decomposition revealed that poultry manure amended paddy straw compost had a c:n ratio of 13.06 and germination index of 132%, compared to 15.29 and 114% of its fungal inoculated counterpart. supplementation of paddy straw with poultry manure was as ... | 2010 | 20056413 |