| effects of different levels of dried sweet potato (ipomoea batatas) leaves inclusion in finisher ration on feed intake, growth, and carcass yield performance of ross broiler chicks. | the effect of supplementation with increasing levels of dried leaves of sweet potato (ipomoea batatas) on feed intake, body weight gain, and carcass yield characteristics of finisher ross broiler chicks was studied at haramaya university, ethiopia. three hundred ross broiler chicks aging 29 days and weighing 540 +/- 5.28 g (mean +/- sd) were randomly distributed to 15 pens, each with 20 chicks, representing five treatment rations each with three replications. dietary treatments consisted of incl ... | 2010 | 19866368 |
| chemical studies on host-virus interactions : i. the effect of bacteriophage adsorption on the multiplication of its host, escherichia coli b with an appendix giving some data on the composition of the bacteriophage, t2. | the addition of active or irradiated t2 bacteriophage and t4 bacteriophage to e. coli b stops bacterial multiplication. the respiratory rate and respiratory quotient of the inhibited bacteria remained at the values observed just before infection. a respiratory rate decrease which occasionally appears can be roughly correlated with change of turbidity of the suspension. an intracellular inhibitor of multiplication appears to be liberated into lysates. a similar substance has been separated from n ... | 1946 | 19871584 |
| chemical studies on host-virus interactions : ii. the chemical simulation of the interference phenomenon by 5-methyl tryptophane. | 5-methyl tryptophane inhibited the multiplication of e. coli b without apparently affecting the rate of its oxygen utilization or r. q. in a synthetic medium. e. coli b, under conditions of inhibition in the presence of this compound, was infected with the bacterial viruses t2 or t4. infected organisms, in the presence of this compound, were unable to reproduce virus, assayable by the plaque method. indeed, the number of infectious centers disappeared at a logarithmic rate in the presence of 5-m ... | 1946 | 19871585 |
| effect of a seashell protein haishengsu on the immunological function of mice with ehrlich ascites tumor. | this study was designed to investigate the effect of a seashell protein haishengsu (hss) on the immuno logical function in mice with ehrlich ascites tumor. ehrlich ascites tumor-bearing mice were divided into three hss groups (25, 50 and 100 mg/kg, i.v., respectively), cyclophosphamide (10 mg i.p.) and control group. the immunological function was assessed by measuring the phagocytizing capacity of the peritoneal macrophages and neutrophils, as well as the number of spleen hemolytic plaque-formi ... | 2009 | 19874239 |
| interactions of thyroid hormones; insulin-like growth factor-1 (igf-1), igf binding proteins, and nutritional anthropometric parameters in school children with goiter detected by palpation. | in the present study we evaluated anthropometric indices, serum thyroid hormones, insulin-like growth factor-1 (igf-1) and igf- binding proteins (igfbps) levels, in children who has palpable goiter at endemic population. we aimed to 1) compare children with palpable goiter with healthy peers, 2) detect interaction of anthropometric indices, serum thyroid hormones, igf-1 and igfbps parameters in both groups 3) evaluate the effects of their nutritional status to these parameters. | 2009 | 19876794 |
| thymidine phosphorylase to dihydropyrimidine dehydrogenase ratio as a predictive factor of response to preoperative chemoradiation with capecitabine in patients with advanced rectal cancer. | to identify if thymidine phosphorylase (tp), dihydropyrimidine dehydrogenase (dpd), and ratio tp/dpd levels in tumor tissues are potential predictive factors for response to combined preoperative chemoradiation with capecitabine, in patients with locally advanced rectal cancer (larc). | 2010 | 19877119 |
| outcomes of minimally invasive endoscopic resection of anterior skull base neoplasms. | the objective of this study was to review clinical outcomes of minimally invasive endoscopic resection (mier) for anterior skull base (asb) neoplasms. | 2010 | 19877265 |
| [effects and toxicity mechanism of 2,2',4,4'-tetrabrominated diphenyl ethers on the homeostasis of thyroid hormone system in c57bl/6 mice]. | to investigate the effects and of toxicity mechanism of 2,2',4,4'-tetrabde (bde-47) on tt3, tt4 and tsh in c57bl/6 mice. | 2009 | 19877504 |
| patterns of radiotherapy practice for pancreatic cancer in japan: results of the japanese radiation oncology study group (jrosg) survey. | to determine the patterns of radiotherapy practice for pancreatic cancer in japan. | 2010 | 19879060 |
| neoadjuvant chemoradiotherapy with capecitabine followed by laparoscopic resection in locally advanced tumors of middle and low rectum - toxicity and complications of the treatment. | the aim of this prospective study is to elucidate feasibility of protocol of neoadjuvant concomitant radiochemotherapy with capecitabine and long course radiotherapy with subsequent laparoscopic rectal resection. we assessed treatment toxicity, downstaging rate, pathological response to the neoadjuvant treatment, surgery complications, rate of conversions and sphincter-preserving surgical procedures, and intraoperative and early postoperative complications too. | 2010 | 19879716 |
| clinical outcome in 520 consecutive danish rectal cancer patients treated with short course preoperative radiotherapy. | the purpose of this study was to analyse the results of preoperative short course radiotherapy in a consecutive, national cohort of patients with rectal cancer. | 2010 | 19880268 |
| clinicopathological features and prognostic factors of proximal gastric carcinoma in a population with high helicobacter pylori prevalence: a single-center, large-volume study in korea. | the incidence of gastric cancers has fallen in recent decades. however, a substantial reduction in helicobacter pylori prevalence and a substantial increase in the incidence of proximal gastric cancer (pgc) have been observed in the west and japan, but not in other east asian countries. the purpose of this large-volume study was to analyze prevalence, clinicopathological features, and prognosis of pgc compared with other types of gastric cancer in korea, where there is high incidence of h. pylor ... | 2010 | 19882188 |
| feed intake, digestibility, nitrogen utilization, and body weight change of sheep consuming wheat straw supplemented with local agricultural and agro-industrial by-products. | effects of supplementing sheep consuming wheat straw with local agro-industrial by-products on feed intake, growth, digestibility and nitrogen utilization were determined. thirty 1-year-old local wethers, with a mean (+/-sd) live weight of 19.8 (+/-1.06) kg, were assigned to five treatments: wheat straw + atella (t1), wheat straw + atella + poultry litter (t2), wheat straw + atella + coffee pulp (t3), wheat straw + atella + coffee pulp + poultry litter (t4), hay + concentrate (t5). a 7-day diges ... | 2010 | 19882225 |
| necessity of quantum coherence to account for the spectrum of time-dependent mutations exhibited by bacteriophage t4. | transcriptase measurements of quantum expectations due to time-dependent coherent states populating informational dna base-pair sites, designated by g-c --> *g-*c, g-c --> g'-c', and a-t --> *a-*t, provide a model for transcription and replication of time-dependent dna lesions exhibited by bacteriophage t4. coherent states are introduced as consequences of hydrogen bond arrangement, keto-amino --> enol-imine, where product protons are shared between two sets of indistinguishable electron lone-pa ... | 2009 | 19882244 |
| molecular phylogeny of acanthamoeba. | after morphological grouping of acanthamoeba by pussard and pons, phylogeny of the genus has been always a big topic to the researchers. because of the variability of morphological characteristics, unchangeable and stable characters have been investigated for phylogenic criteria. isoenzyme and mitochondrial dna rflp (mt dna rflp) analyses revealed different patterns among strains assigned to a same species. therefore, these characteristics would be considered as tools for strain discrimination t ... | 2009 | 19885332 |
| p53 mutation status predicts pathological response to chemoradiotherapy in locally advanced esophageal cancer. | the p53 gene promotes cell-cycle arrest and apoptosis upon dna damage and is associated with chemo- and radiosensitivity of cancer cells. however, its clinical significance has not been confirmed, especially in squamous cell carcinoma of the esophagus (escc). we investigated the correlation between p53 disorders (gene mutation and protein accumulation) and the effects of chemoradiotherapy (crt). | 2010 | 19885698 |
| [local recurrence after the sphincter-saving operations and abdominal perineal resection in rectal cancer]. | by local recurrence we define the appearance of the same anatomopathological type of cancer like the one initially described in the primary tumor, limited at the rectum or pelvis.the study is based on the analysis of all the cases with rectal cancer who undergone surgical procedures in surgical clinic no.2 tg. mures in the last 5 years. using the most important parameters for each patient we identified some risk factors for the recurrence of the rectal cancer: surgical procedures--there were no ... | 2009 | 19886048 |
| topoisomerase ii alpha--a fundamental prognostic factor in breast carcinoma. | because of the introduction of modern diagnostic methods, numerous prognostic and predictive factors have been recognized and are today considered classic, yet they seem to be insufficient in assessment of prognosis, hence the need for further investigations. among factors newly discovered by molecular techniques, there are class i and ii topoisomerases, the role of which as prognosticators has not been fully determined. the objective of the present investigation was the assessment of topoisomer ... | 2009 | 19886180 |
| gemcitabine as single agent in pretreated t-cell lymphoma patients: evaluation of the long-term outcome. | peripheral t-cell lymphoma unspecified (ptclu) and mycosis fungoides (mf) often show resistance to conventional chemotherapy. gemcitabine should be considered a suitable option. we report the long-term update of 39 pretreated t-cell lymphoma patients treated with gemcitabine. | 2010 | 19887465 |
| remission of grave's disease after oral anti-thyroid drug treatment. | to evaluate remission rate of anti-thyroid drug treatment in patients with grave's disease, and to study the factors associated with remission. | 2009 | 19889263 |
| results of european pooled analysis of iort-containing multimodality treatment for locally advanced rectal cancer: adjuvant chemotherapy prevents local recurrence rather than distant metastases. | the purpose of this study is to analyze the pooled results of multimodality treatment of locally advanced rectal cancer (larc) in four major treatment centers with particular expertise in intraoperative radiotherapy (iort). | 2010 | 19889621 |
| surgical outcomes and prognostic factors for t4 gastric cancers. | in locally advanced gastric carcinomas that have invaded adjacent organs, the prognosis is poor. when combined resections are performed in t4 gastric cancers, a high morbidity rate is reported and it is inconclusive as to whether or not there is an improvement in the survival rate. we investigated surgical outcomes and analysed the prognostic factors for t4 gastric cancers. | 2009 | 19892622 |
| preconditioning with glucose-insulin-potassium solution and restoration of myocardial function during coronary surgery. | the administration of glucose-insulin-potassium (gik) solution has beeen shown to exert cardioprotective and immunomodulatory properties in coronary disease. 49 patients (pts.) for coronary surgery were randomly assigned to receive high-dose gik treatment (30% glucose, insulin 2 iu.kg(-1).l(-1) and k(+) 80 mmo/l solution; 1 ml/kg/h); low-dose gik treatment (10% glucose, insulin 32 iu l(-1) and k(+) 80 mmol/l solution; 1 ml/kg/h) or control treatment (ringer solution 1 ml/kg/h). haemodynamic meas ... | 2009 | 19893109 |
| pedicle morphometry for thoracic screw fixation in ethnic koreans : radiological assessment using computed tomographic myelography. | in the thoracic spine, insertion of a pedicle screw is annoying due to small pedicle size and wide morphological variation between different levels of the spine and between individuals. the aim of our study was to analyze radiologic parameters of the pedicle morphometry from t1 to t8 using computed tomographic myelography (ctm) in korean population. | 2009 | 19893719 |
| area under the curve of tsh after levothyroxine withdrawal versus administration of recombinant human tsh (rhtsh): possible implications for tumor growth. | the levothyroxine withdrawal (l-t4) for some weeks results in prolonged exposure to elevated tsh. in contrast, administration of recombinant human tsh (rhtsh) promotes a short period of hyperthyrotropinemia. the objective of this study was to compare the area under the curve (auc) of tsh obtained after l-t4 withdrawal versus administration of rhtsh. | 2009 | 19893921 |
| the baseplate wedges of bacteriophage t4 spontaneously assemble into hubless baseplate-like structure in vitro. | the baseplate of phage t4 is an important model system in viral supramolecular assembly. the baseplate consists of six wedges surrounding the central hub. we report the first successful attempt at complete wedge assembly using an in vitro approach based on recombinant proteins. the cells expressing the individual wedge proteins were mixed in a combinatorial manner and then lysed. using this approach, we could both reliably isolate the complete wedge along with a series of intermediate complexes ... | 2010 | 19896486 |
| genetic insertions and diversification of the polb-type dna polymerase (gp43) of t4-related phages. | in escherichia coli phage t4 and many of its phylogenetic relatives, gene 43 consists of a single cistron that encodes a polb family (polb-type) dna polymerase. we describe the divergence of this phage gene and its protein product (gp43) (gene product 43) among 26 phylogenetic relatives of t4 and discuss our observations in the context of diversity among the widely distributed polb enzymes in nature. in two t4 relatives that grow in aeromonas salmonicida phages 44rr and 25, gene 43 is fragmented ... | 2010 | 19896487 |
| sex steroid levels, oocyte maturation and spawning performance in waigieu seaperch (psammoperca waigiensis) exposed to thyroxin, human chorionic gonadotropin, luteinizing hormone releasing hormone and carp pituitary extract. | in the present study, we have investigated the sex steroid hormone levels, oocyte maturation and spawning performance in waigieu seaperch (psammoperca waigiensis) exposed to different doses (0, (control), 0.05, 0.25 and 0.5 mg/kg fish) of thyroxin (t(4)) both through diet (continuously) and injection (single injection). in addition, we also studied plasma steroid hormone levels and spawning performances in female fish injected with a single dose of d-ala(6), pro(9)-net-mgnrh (lhrha: 50 microg/kg ... | 2010 | 19896549 |
| olfactory ensheathing cells reduce duration of autonomic dysreflexia in rats with high spinal cord injury. | autonomic dysreflexia is a common complication in high spinal cord injury and can result in serious consequences and death. here we have examined the effect of acute transplantation of olfactory ensheathing cells on cardiovascular functions in rats. after t4 transection, radio-telemetric recording in conscious animals was used to study blood pressure and heart rate at rest and during autonomic dysreflexia for up to 8 weeks post-injury. olfactory ensheathing cells from syngeneic rats were transpl ... | 2010 | 19896908 |
| effect of supplementation of simada sheep with graded levels of concentrate meal on feed intake, digestibility and body-weight parameters. | the experiment consisting of 7 days of digestibility and 90 days of feeding trial was conducted at wogda (ethiopia) to determine the effect of supplementation of graded levels of concentrate mix (cm) on feed intake, digestibility, and body weight (bw) change in hay-based feeding of simada sheep. twenty-yearling simada sheep with a mean initial bw of 17.9 +/- 0.81 kg (mean +/- sd) were used in randomized complete block design arranged into five blocks of four animals. the four dietary treatments ... | 2010 | 19898949 |
| dissociation kinetics of the groel-gp31 chaperonin complex studied with förster resonance energy transfer. | propagation of bacteriophage t4 in its host escherichia coli involves the folding of the major capsid protein gp23, which is facilitated by a hybrid chaperone complex consisting of the bacterial chaperonin groel and the phage-encoded co-chaperonin, gp31. it has been well established that the groel-gp31 complex is capable of folding gp23 whereas the homologous groel-groes complex cannot perform this function. to assess whether this is a consequence of differences in the interactions of the protei ... | 2009 | 19899806 |
| biomolecular response of oxanine in dna strands to t4 polynucleotide kinase, t4 dna ligase, and restriction enzymes. | oxanine (oxa), generated from guanine (gua) by no- or hno(2)-induced nitrosative oxidation, has been thought to cause mutagenic problems in cellular systems. in this study, the response of oxa to different enzymatic functions was explored to understand how similarly it can participate in biomolecular reactions compared to the natural base, gua. the phosphorylation efficiency of the t4 polynucleotide kinase was highest when oxa was located on the 5'-end of single stranded dnas compared to when ot ... | 2010 | 19900415 |
| nodal staging score: a tool to assess adequate staging of node-negative colon cancer. | adequate nodal staging of colon cancer has been defined as pathologic examination of at least 12 lymph nodes. we sought to refine this definition by quantifying the likelihood that a pathologically node-negative patient has, indeed, no positive nodes. | 2009 | 19901106 |
| multiple extradural spinal arachnoid cysts causing diffuse myelomalacia of the spinal cord. | extradural spinal cyst is a rare cause of compression myelopathy. it is usually solitary and its typical location is posterior to the spinal cord. we present a case of multiple spinal arachnoid cysts causing diffuse myelomalacia secondary to a significant compression of the spinal cord with no symptom relief after surgical decompression. | 2009 | 19901717 |
| prognostic value of microvascular density in dukes a and b (t1-t4, n0, m0) colorectal carcinomas. | aproximatelly 30% of patients operated on for colorectal cancer (crc), with an expectedly favourable prognosis (dukes a-b/t1-t4, n0, m0) suffer recurrence and/or die. | 2009 | 19902004 |
| reconstruction of extensive composite oromandibular defects with simultaneous free anterolateral thigh fasciocutaneous and fibular osteocutaneous flaps. | massive composite defects of the face are difficult to reconstruct. such defects are usually created after ablation of advanced cancers of the head and neck region. the use of a free fibular osteocutaneous flap for the bone and mucosal lining of the oral cavity and anterolateral thigh flap for the outer cutaneous lining are well established. we present our experience of using these two flaps simultaneously in the reconstruction of such defects and to evaluate the outcome. there were a total of 1 ... | 2010 | 19902408 |
| proton beam radiotherapy for uveal melanomas at nice teaching hospital: 16 years' experience. | to present the results of uveal melanomas treated at nice teaching hospital. | 2010 | 19910136 |
| short-term exposure to triclosan decreases thyroxine in vivo via upregulation of hepatic catabolism in young long-evans rats. | triclosan (5-chloro-2-(2,4-dichlorophenoxy)-phenol) is a chlorinated phenolic antibacterial compound found in consumer products. in vitro human pregnane x receptor activation, hepatic phase i enzyme induction, and decreased in vivo total thyroxine (t4) suggest adverse effects on thyroid hormone homeostasis. current research tested the hypothesis that triclosan decreases circulating t4 via upregulation of hepatic catabolism and transport. weanling female long-evans rats received triclosan (0-1000 ... | 2010 | 19910387 |
| clinicopathologic analysis of ampullary neoplasms in 450 patients: implications for surgical strategy and long-term prognosis. | whether ampullary neoplasms are best surgically managed by pancreaticoduodenectomy versus local ampullectomy is controversial. we sought to examine the outcome of patients undergoing pancreaticoduodenectomy versus ampullectomy, as well as to identify factors predictive of lymph node metastasis in patients with ampullary neoplasms. | 2010 | 19911239 |
| mediastinal gastroenteric cyst in a neonate containing respiratory-type epithelium and pancreatic tissue. | mediastinal gastroenteric cyst is an uncommon congenital malformation and a distinct histopathological entity within the family of foregut duplication cysts. this lesion is mainly encountered in neonates and infants. histologically, it is characterized by double-layered smooth muscle wall and gastric lining mucosa. we report on a case of a 2-day-old girl, with a posterior mediastinal cystic mass associated with t3-t4 hemivertebrae, presenting with severe respiratory distress. the cyst was multil ... | 2009 | 19911364 |
| [child-"euthanasia" in nazi-germany--the case of the psychiatric clinic brandenburg-görden]. | the article shows, through a study of the berlin-brandenburg region, that children and juveniles who were subjected to the killings of diseased and disabled, or mentally retarded persons during the third reich did not only fall victim to the operations of the "reichsausschuss" ("reich commission for registration of severe disorders in childhood"). many were also included in the gas chamber killings of the "t4"-action and in various decentralized killing actions. to gain scientific knowledge, the ... | 2009 | 19911765 |
| 'staged' liver resection in synchronous and metachronous colorectal hepatic metastases: differences in clinicopathological features and outcome. | aim  approximately 25% of the patients with colorectal cancer already have liver metastases at diagnosis and another 30% will develop them subsequently. the features and prognosis of patients with synchronous and metachronus colorectal liver metastases, treated with primary resection first followed by partial liver resection were analysed. method  curative staged resection of liver metastases was performed in 272 consecutive patients. demographics, characteristics of the primary tumour and metas ... | 2009 | 19912286 |
| complete sequencing of tunisian redspotted grouper nervous necrosis virus betanodavirus capsid gene and rna-dependent rna polymerase gene. | finfish nodaviruses (betanodaviruses) can cause highly destructive infections in numerous species of farmed marine fish larvae and juveniles worldwide. the betanodavirus genome consists of two single-stranded positive-sense rna molecules (rna1 and rna2). the virus can be classified into four genotypes based on the partial sequences of the coat protein (cp) gene (t2 and t4 regions). currently, genomic sequence information for rna1 regions of rna2 outside of t2 and t4 is less well documented. this ... | 2010 | 19912455 |
| two-chaperone assisted soluble expression and purification of the bacteriophage t4 long tail fibre protein gp37. | bacteriophage t4 recognises its host cells through its long tail fibre protein gene product (gp) 37. gp37 is a protein containing 1026 amino acids per monomer, forming a fibrous parallel homotrimer at the distal end of the long tail fibres. the other distal half-fibre protein, gp36, is much smaller, forming a trimer of 221 amino acids per monomer. functional and structural studies of gp37 have been hampered by the inability to produce suitable amounts of it. we produced soluble gp37 by co-expres ... | 2010 | 19913618 |
| abnormalities of thyroid function in japanese patients with metastatic renal cell carcinoma treated with sorafenib: a prospective evaluation. | the objective of this study was to characterize features of thyroid dysfunction in japanese patients with metastatic renal cell carcinoma (rcc) who were treated with sorafenib. we performed a prospective observational study including 69 japanese patients who were diagnosed as having metastatic rcc refractory to cytokine therapy and subsequently treated with sorafenib for at least 12 weeks. thyroid function was assessed before and every 4 weeks after the initiation of sorafenib treatment. of the ... | 2010 | 19914105 |
| the significance of a positive bladder neck margin after radical prostatectomy: the american joint committee on cancer pathological stage t4 designation is not warranted. | the american joint committee on cancer currently designates invasion of the bladder neck as a pt4 lesion. however, retrospective analyses have not demonstrated biochemical recurrence-free survival after radical prostatectomy to be consistent with other t4 lesions. we examined biochemical recurrence-free survival and cancer specific survival in men with a positive bladder neck margin. | 2010 | 19914651 |
| the hypothalamus-pituitary-thyroid axis in critical illness. | the thyroid axis is comprised of thyrotropin-releasing hormone (trh) at the level of the hypothalamus which stimulates the pituitary to release thyrotropin (tsh). tsh in turn stimulates the thyroid to secrete the pro-hormone thyroxin (t4) and to a lesser extent the receptor active hormone tri-iodothyronine (t3). the majority of circulating t3 is generated by peripheral conversion of t4 by the intracellular iodothyronine deiodinases. thyroid hormone (th) is transported over the cell membrane by s ... | 2009 | 19915227 |
| effect of pre-drying treatments and storage on color and phenolic composition of green honeybush (cyclopia subternata) herbal tea. | the effect of various pre-drying treatments and storage temperatures on the color (l*, a*, b*, chroma, and hue angle) and phenolic composition of green cyclopia subternata was investigated. pre-drying treatments, which included comminution+drying (t2), steaming (ca. 90-93 degrees c/60 s)+comminution + drying (t3), and comminution+steaming+drying (t4), had a detrimental effect (p<0.05) on the color parameters relative to the control (t1) (drying of intact leaves). all drying took place at 40 degr ... | 2010 | 19916502 |
| unexplained amenorrhea in a patient taking methotrexate for the treatment of rheumatoid arthritis. | the cause of secondary amenorrhea in the following case cannot be explained by traditional etiologies. we therefore questioned whether long-term methotrexate treatment played a role as an endometrial inhibitor. | 2010 | 19916871 |
| bridged oligonucleotides as molecular probes for investigation of enzyme-substrate interaction and allele-specific analysis of dna. | the efficiency of enzymatic conversion of dna complexes containing non-nucleotide inserts has been studied. t4 dna ligase and taq dna polymerase have been included in the study as examples of widely used dna-dependent enzymes. a series of substrate dna complexes have been formed using native oligonucleotides and bridged ones bearing non-nucleotide inserts based on phosphodiesters of di-, tetra-, or hexaethylene glycol, 1,5-pentanediol, 1,10-decanediol, and 3-hydroxy-2(hydroxymethyl)-tetrahydrofu ... | 2009 | 19916912 |
| accurate guanine:cytosine discrimination in t4 dna ligase-based single nucleotide polymorphism analysis using an oxanine-containing ligation fragment. | t4 dna ligase-based mismatch detection methods have been proposed as useful strategies for single nucleotide polymorphism (snp) analyses. however, there is a critical problem for cytosine/thymine (c/t) snp analyses: guanine:thymine (g:t) mismatch is not distinguished from guanine:cytosine (g:c). here we employed chemically modified nucleobases, such as oxanine and hypoxanthine, at the end of a ligation fragment and analyzed their influence on the ligation efficiency between g:c and g:t. successf ... | 2010 | 19917262 |
| triclosan and anuran metamorphosis: no effect on thyroid-mediated metamorphosis in xenopus laevis. | nieuwkoop and faber stage 51 xenopus laevis larvae were exposed for 21 days to four different concentrations of triclosan (tcs): <0.2 (control), 0.6, 1.5, 7.2, or 32.3 microg tcs/l. primary endpoints were survival, hind limb length, body length (whole; snout to vent), developmental stage, wet whole body weight, and thyroid histology. thyroid hormone (th) concentrations were determined in whole thyroid and plasma samples from stage-matched exposure day 21 specimens. th receptor-beta (trbeta) expr ... | 2010 | 19917620 |
| the effect of thyroid hormones on the white adipose tissue gene expression of pai-1 and its serum concentration. | metabolic syndrome is associated with an increased risk of developing cardiovascular diseases and plasminogen activator inhibitor 1 (pai-1) overexpression may play a significant role in this process. a positive correlation between adipose tissue gene expression of pai-1 and its serum concentration has been reported. furthermore, high serum levels of thyroid hormones (t3 and t4) and pai-1 have been observed in obese children. the present study evaluates the impact of thyroid hormone treatment on ... | 2009 | 19918669 |
| [short- and long-term effects of the outpatient medical rehabilitation for patients with asbestosis]. | the aim of this study was to evaluate the effects of an outpatient medical rehabilitation (omr) mainly composed of exercise therapy and sports for patients with asbestosis. following the model of hamburg the omr focuses on keeping up lasting effects. | 2010 | 19918720 |
| references for growth and pubertal development from birth to 21 years in flanders, belgium. | due to the secular trend in length and height, growth references need to be updated regularly. reference charts that were until recently used in belgium are based on samples collected more than 30 years ago, and references for body mass index (bmi) and pubertal development have not been established before. | 2009 | 19919503 |
| intensity-modulated radiotherapy for recurrent and second primary head and neck cancer in previously irradiated territory. | to evaluate re-irradiation using imrt for recurrent and second primary head and neck cancer in previously irradiated territory. | 2009 | 19919885 |
| thyroid hormone supplementation improves bovine embryo development in vitro. | early embryo development (eed) forms the basis of assisted reproductive technologies (arts), which are used to treat human infertility and to propagate other mammalian species. thyroid hormones (ths) play an important role in the post-implantation development of the embryo in mammals; however, the effects of ths on pre-attachment embryos are not known. currently utilized in-vitro embryo production media are devoid of ths and hence our main objective was to examine whether ths affected eed in a b ... | 2010 | 19920067 |
| anesthetic management of a patient with hyperthyroidism due to hydatidiform mole. | secondary hyperthyroidism can often complicate gestational trophoblastic disease, a malignant uterine cancer. we report here the perioperative management of hyperthyroidism due to hydatidiform mole. a 53-year-old woman underwent emergency surgery due to suspicion of hydatidiform mole. tachycardiac atrial fibrillation was detected by electrocardiography at the preoperative examination. no abnormalities were found in blood count, coagulation, biochemical tests, chest radiographs, or respiratory fu ... | 2009 | 19921374 |
| organochlorine compounds, iodine intake, and thyroid hormone levels during pregnancy. | the effect of organochlorine compounds (ocs) on thyroid function, as well as the potential confounding effect of iodine intake, was studied in a large sample of pregnant women from two population-based cohort studies in sabadell (n = 520) and gipuzkoa (n = 570), spain. thyroid hormones (free t4 and total t3), thyrotropin, and polychlorinated biphenyls (pcb congeners 118, 138, 153, and 180), hexachlorobenzene (hcb), beta-hexachlorocyclohexane (beta-hch), dichlorodiphenyl dichloroethylene (p'p'-dd ... | 2009 | 19921913 |
| [anesthesic management in telerobotic totally endoscopic coronary artery bypass grafting]. | to investigate the strategies for anesthetic management for totally endoscopic coronary artery bypass grafting with the da vinci s surgical system. | 2009 | 19923068 |
| lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy. | we assessed the expression and the prognostic role of lactate dehydrogenase 5 (ldh5, the major ldh isoenzyme involved in anaerobic glycolysis) in patients with squamous cell head and neck cancer (schnc). | 2009 | 19923867 |
| prenatal and postnatal impact of perfluorooctane sulfonate (pfos) on rat development: a cross-foster study on chemical burden and thyroid hormone system. | perfluorooctane sulfonate (pfos), an environmentally persistent organic pollutant, has been reported to be transferred to the developing organisms via both placenta and breast milk. a cross-foster model was used to determine whether prenatal or postnatal exposure to pfos alone can disturb the th homeostasis in rat pups, and if so, which kind of exposure is a major cause of th level alteration. pregnant rats were fed standard laboratory rodent diet containing 0 (control) or 3.2 mg pfos/kg through ... | 2009 | 19924978 |
| pharmacotherapy of actinic keratosis. | actinic keratosis (ak) represents the initial intraepidermal manifestation of abnormal keratinocyte proliferation with the potential of progression to squamous cell carcinoma (scc). when in limited numbers, clinically visible aks are treated individually with ablative and/or surgical procedures (lesion-directed treatment), while multiple and sublinical aks are treated with field-directed therapies that use ablative, nonablating and other topically applied treatment modalities. owing to difficult ... | 2009 | 19925043 |
| a 10-year wildlife survey of 15 species of canadian carnivores identifies new hosts or geographic locations for trichinella genotypes t2, t4, t5, and t6. | a survey of wild carnivores in canada was conducted over a 10-year period to determine the prevalence and genotypes of trichinella. muscle samples collected from 1409 animals representing 15 hosts species were enzymatically digested to recover trichinella larvae. larvae were recovered from a total of 287 (20.4%) animals and pcr identified four genotypes of trichinella. trichinella nativa was found in 5 host species and was the most commonly found genotype. trichinella t6 was present in 7 species ... | 2010 | 19926223 |
| differences in male and female spino-pelvic alignment in asymptomatic young adults: a three-dimensional analysis using upright low-dose digital biplanar x-rays. | a three-dimensional analysis of spino-pelvic alignment in 60 asymptomatic young adult males and females. | 2009 | 19927088 |
| pathological findings and prostate-specific antigen outcomes after laparoscopic radical prostatectomy for high-risk prostate cancer. | therapy (case series) level of evidence 4. | 2010 | 19930177 |
| prospective study of daily low-dose nedaplatin and continuous 5-fluorouracil infusion combined with radiation for the treatment of esophageal squamous cell carcinoma. | protracted low-dose concurrent chemotherapy combined with radiation has been proposed for enhanced treatment results for esophageal cancer. we evaluated the efficacy and the toxicity of a novel regimen of daily low-dose nedaplatin (cis-diammine-glycolatoplatinum) and continuous infusion of 5-fluorouracil (5-fu) with radiation in patients with esophageal squamous cell carcinoma. | 2009 | 19930599 |
| [effects of different doses of ulinastatin on inflammatory response and pulmonary function after cardiopulmonary bypass]. | to evaluate the effect of ulinastatin (uti) on the changes in inflammatory cytokines and inflammatory response as a result of cardiopulmonary bypass (cpb) in cardiac valvular replacement surgery and to investigate the protective effect of uti on lungs. | 2009 | 19930883 |
| [protective effect of ulinastatin on lung injury induced by simultaneous pancreas-kidney transplantation in piglet]. | to evaluate the effects of ulinastatin (uti) on lung injury induced by simultaneous pancreas-kidney transplantation in piglet. | 2009 | 19930886 |
| improved soluble expression and characterization of the hc domain of clostridium botulinum neurotoxin serotype a in escherichia coli by using a pcr-synthesized gene and a trx co-expression strain. | botulinum neurotoxin serotype a (bont/a) is an extremely potent bacterial protein toxin. the hc fragment of bont/a (ahc) was shown to be non-toxic, antigenic, and capable of eliciting a protective immunity in animals challenged with homologous bont. in this study, we synthesized ahc gene by using t4 dna ligase and pcr. the ahc was expressed at a high level in escherichia coli successfully. because of using the trx co-expression strain, the expressed ahc is in a soluble and active form. the yield ... | 2010 | 19932180 |
| induction chemotherapy before sleeve lobectomy for lung cancer: immediate and long-term results. | induction chemotherapy does not increase the morbidity and mortality rates of bronchoplastic procedures, but the long-term efficiency remains unclear. the purpose of this retrospective study was to analyze the impact of chemotherapy on resectability and long-term survival. | 2009 | 19932225 |
| simple method for determining the need for sternotomy/manubriotomy with the anterior approach to the cervicothoracic junction. | frequently, the cervicothoracic junction can be reached through a simple anterior approach. in some cases, access to this region requires a much more aggressive surgical intervention, such as manubriotomy or sternotomy. information regarding the need for such interventions is particularly useful to have preoperatively to guide surgical planning as well as discussions regarding surgical risks and expected morbidities. whereas methods utilizing magnetic resonance imaging have been proposed for det ... | 2009 | 19935010 |
| evaluation scale to assess the accuracy of cuff-less blood pressure measuring devices. | the call for early detection of hypertension and cardiac events creates a heavy demand for devices that can be used for blood pressure (bp) monitoring at home and in ambulatory settings. an emerging type of bp monitors without an occluding cuff has drawn great attentions for this application because it is comfortable and capable of providing continuous readings. for the development the cuff-less devices, it is crucial for the clinicians and engineers to joint efforts in establishing an evaluatio ... | 2009 | 19935198 |
| eeg characteristics in depression, "negative" and "positive" schizophrena. | qeeg investigations present differences in the comparison of schizophrenic patients and healthy examinees, as well as of depressive patients and healthy controls. the comparison of "positive" and "negative" schizophrenia also presents differences in the qeeg parameters. changes in qeeg are various in these studies, but not always consistent. in this research we wanted to compare "positive" schizophrenia, "negative" schizophrenia and depression. | 2009 | 19935497 |
| surgical outcomes of endoscopic management of adenocarcinoma of the sinonasal cavity. | to report the surgical outcomes of endoscopic resection of adenocarcinomas of the sinonasal cavity. | 2009 | 19936358 |
| serum thyroid hormone profile in critically ill children. | to study thyroid hormone profile in critically ill children and its correlation to disease severity and clinical outcome. | 2009 | 19936665 |
| central hypothyroidism. | a 15-mth-old male child of consanguineous parents, presented with classical features of congenital hypothyroidism. serum total thyroxine (t4), total triiodothyronine (t3) and tsh were low. there was no evidence of deficiency of other pituitary hormones. magnetic resonance imaging of the pituitary was normal. tshb gene sequencing revealed a homozygous missense mutation due to single base substitution g?a at codon 85 resulting in change from glycine to arginine. this mutation in tshb gene has been ... | 2010 | 19936667 |
| endocrine function in children acutely following severe traumatic brain injury. | despite the prevalence of frontal injury following traumatic brain injury (tbi) in adults and children with potentially concomitant hypothalamic and pituitary involvement, endocrine dysfunction acutely following tbi has not been well studied in children. | 2010 | 19937245 |
| thyroid hormones according to gestational age in pregnant spanish women. | thyroid function changes during pregnancy and maternal thyroid dysfunction have been associated with adverse outcomes. our aim was to evaluate thyroid hormones levels in pregnant women resident in aragon, spain. | 2009 | 19939287 |
| impact of positive pleural lavage cytology on survival in patients having lung resection for non-small-cell lung cancer: an international individual patient data meta-analysis. | pleural lavage cytology is the microscopic study of cells obtained from saline instilled into and retrieved from the chest during surgery for non-small-cell lung cancer. the aims of this study were to collate multi-institutional individual patient data for meta-analysis to determine independence as a prognostic marker and to characterize the impact of positive results on stage-adjusted survival. | 2010 | 19939412 |
| evidence for thyroid endocrine disruption in wild fish in san francisco bay, california, usa. relationships to contaminant exposures. | it is well documented that many coastal and estuarine environments adjacent to developed and industrialized urban centers, such as the san francisco bay area, are significantly contaminated by anthropogenic chemicals. however, it is not well understood to what extent existing contaminants, many with continuing inflows into the environment, may impact exposed wildlife. this study provided an initial characterization of thyroid endocrine-related effects and their relationship to accumulated contam ... | 2010 | 19939474 |
| delayed presentation of tetraparesis following posterior thoracolumbar spinal fusion and instrumentation for adolescent idiopathic scoliosis. | case report. | 2009 | 19940725 |
| fecal triiodothyronine and thyroxine concentrations change in response to thyroid stimulation in steller sea lions (eumetopias jubatus). | variation in concentrations of thyroid hormones shed in feces may help to identify physiological states of animals, but the efficacy of the technique needs to be validated for each species. we determined whether a known physiological alteration to thyroid hormone production was reflected in hormone concentrations in the feces of steller sea lions (eumetopias jubatus). we quantified variation of triiodothyronine (t3) and thyroxine (t4) concentrations in feces following two intramuscular injection ... | 2010 | 19941866 |
| medications that distort in vitro tests of thyroid function, with particular reference to estimates of serum free thyroxine. | the combination of serum thyroid-stimulating hormone (tsh) with measurement of circulating thyroid hormones greatly improves sensitivity and specificity of thyroid diagnosis, but these assays are not impeccable. estimation of serum free t4 conveniently accommodates variations in the concentration of thyroxine-binding globulin (tbg), but no current technique reliably reflects the in vivo free t4 concentration in numerous other situations. the effect of circulating competitors that increase t4 and ... | 2009 | 19942151 |
| sex steroids and the thyroid. | thyroid function is modulated by genetic and environmental causes as well as other illnesses and medications such as gonadal or sex steroids. the latter class of drugs (sex steroids) modulates thyroid function. gonadal steroids exert their influence on thyroid function primarily by altering the clearance of thyroxine-binding globulin (tbg). while oestrogen administration causes an increase in serum tbg concentration, androgen therapy results in a decrease in this binding protein. these effects o ... | 2009 | 19942152 |
| [surgery and additional protontherapy for treatment of invasive and recurrent squamous cell carcinomas: technique and preliminary results]. | invasive squamous cell carcinomas are uncommon neoplasias with high recurrence and mortality rates. the improvement of tumoral control requires additional treatments such as cryotherapy, topical chemotherapy, and radiotherapy. we present the technique and preliminary results of associating treatment with surgery and proton beam therapy for recurrent and invasive squamous cell carcinomas. | 2009 | 19942315 |
| surgical management of the thyroid nodules. | the evaluation and the management of thyroid nodules have evolved during the last years. before the 1980's the strategy was relatively simple, the palpable thyroid nodules were explored by scintigraphy, a method that separated the "hot" nodules (with a low possibility of being cancer) from the "cold" nodules (that included most types of cancer). during the last 25 years, the development of new techniques such as hrus( high resolution ultrasonography) and hrus-guided fnab (fine-needle aspiration ... | 2009 | 19943555 |
| demographic data of laryngeal cancer at the instituto nacional de cancerología in mexico city. | we undertook this study to describe the demographic data of patients with laryngeal cancer treated at the instituto nacional de cancerología in mexico city. | 2009 | 19944022 |
| a microrna expression profile defining the invasive bladder tumor phenotype. | objective: the purpose of this study was to identify microrna (mirna) involved in the transition between the noninvasive and invasive urothelial carcinoma of the bladder (ucb) phenotype. methods: differential expression of mirna was identified in a microarray format between noninvasive and invasive ucb cell lines and confirmed using quantitative reverse transcriptase-polymerase chain reaction (qrt-pcr) within this cell panel. normalization of qrt-pcr with mir-222 was established from the microar ... | 2009 | 19945312 |
| exposure to de-71 alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis of zebrafish larvae. | polybrominated diphenyl ethers (pbdes) have the potential to disrupt thyroid hormone homeostasis, but the molecular mechanisms underlying this process have not yet been clarified. in the present study, zebrafish (danio rerio) embryos were exposed to a low concentration (0, 1, 3, and 10microg/l) of de-71 from fertilization to 14 days thereafter. the whole-body content of thyroid hormone and transcription of genes in the hypothalamic-pituitary-thyroid (hpt) axis were analyzed. exposure to up to 10 ... | 2010 | 19945756 |
| rare case of primary spinal ependymomatosis occurring in a 26-year-old man: a case report. | the authors report a rare case of primary spinal ependymomatosis in a young adult man. multiple primary ependymomatous lesions were seen on magnetic resonance imaging and no anaplasia was identified on the surgical-pathological analysis. the aetio-pathological mechanism and surgical significance of this rare occurrence is discussed. | 2009 | 19946548 |
| a study comparing endoscopic ultrasound (eus) and computed tomography (ct) in staging oesophageal cancer and their role in clinical decision making. | computed tomography (ct) and endoscopic ultrasound (eus) are part of the regular preoperative staging protocol in oesophageal cancer. at present, eus is increasingly being used for preoperative locoregional staging of oesophageal cancer. the aim of this study is to compare eus and ct findings and their role in clinical decision making. | 2010 | 19946764 |
| [construction of recombinant adenovirus vector containing rat insulin-like growth factor 1 gene and its expression in islet beta-cells]. | this study was aimed to construct the recombinant adenovirus containing rat insulin-like growth factor 1(rigf-1), and then to investigate its expression in islet beta-cells. rna was extracted using trizol from rat livers. rigf-1 cdna was obtained using rt-pcr. the purified rt-pcr products and padtrack-cmv were digested using bg1 ii and ecor v and religated by t4 dna ligase, then transformed into electro-competent jm109 bacteria and selected on kanamycin lb plates. this plasmid pad-cmv-rigf-1 was ... | 2009 | 19947492 |
| synthesis of hetero-telechelic alpha,omega bio-functionalized polymers. | reversible addition-fragmentation chain transfer (raft) polymerization was used to synthesize poly[diethylene glycol monomethylether methacrylate] (pdegma) (m(n) = 6250 g/mol, pdi = 1.14) with a pentafluorophenyl (pfp) activated ester and a dithioester end group. the hormone thyroxin (t4) was quantitatively attached to the pfp activated ester alpha end group via its amino group. the omega-terminal dithioester was not harmed by this reaction and was subsequently aminolyzed in the presence of n-bi ... | 2010 | 19947639 |
| oriented immobilization of bacteriophages for biosensor applications. | a method was developed for oriented immobilization of bacteriophage t4 through introduction of specific binding ligands into the phage head using a phage display technique. fusion of the biotin carboxyl carrier protein gene (bccp) or the cellulose binding module gene (cbm) with the small outer capsid protein gene (soc) of t4 resulted in expression of the respective ligand on the phage head. recombinant bacteriophages were characterized in terms of infectivity. it was shown that both recombinant ... | 2010 | 19948867 |
| revised tn categorization for colon cancer based on national survival outcomes data. | the sixth edition of american joint committee on cancer (ajcc) cancer staging manual for colon cancer subdivided stage ii into iia (t3n0) and iib (t4n0) and stage iii into iiia (t1-2n1m0), iiib (t3-4n1m0), and iiic (anytn2m0). subsequent analyses supported revised substaging of stage iii because of improved survival for t1-2n2 versus t3-4n2 and t4n1 survival was more similar to t3-4n2 than to t3n1. the ajcc hindgut taskforce sought population-based validation that depth of invasion and nodal sta ... | 2010 | 19949014 |
| revised tumor and node categorization for rectal cancer based on surveillance, epidemiology, and end results and rectal pooled analysis outcomes. | the sixth edition of the american joint committee on cancer (ajcc) rectal cancer staging subdivided stage ii into iia (t3n0) and iib (t4n0) and stage iii into iiia (t1-2n1m0), iiib (t3-4n1m0), and iiic (anytn2m0). subsequent analyses supported revised substaging of stage iii as a result of improved survival with t1-2n2 versus t3-4n2 and survival of t4n1 more similar to t3-4n2 than t3n1. the ajcc hindgut taskforce sought population-based validation that depth of invasion interacts with nodal stat ... | 2010 | 19949015 |
| the first appearance of sympathetic ganglia in human embryos at stage 13. | the primordia of the sympathetic trunk ganglia were traced on serial sections of 10 embryos at stage 13 (32 postovulatory days). it was found that in all embryos, these primordia were present in the thoracic level t4 to t9 and they appeared as scattered aggregates of cells lying dorsally and laterally to the dorsal aortae. | 2009 | 19950069 |
| [impact of tnm staging and treatment mode on the prognosis of non-small cell lung cancer]. | to study the impact of tnm staging and combined treatment mode on the survival of non-small cell lung cancer (nsclc) patients. | 2009 | 19950561 |
| [cloning and prokaryotic expression of bifidobacterium infantis-mediated skdr and its effect on proliferation of vascular endothelial cells]. | to construct bifidobacterium infantis-mediated skdr gene transferring system and to investigate its effect on the proliferation of vascular endothelial cells. | 2009 | 19950583 |