| viridenomycin, a new antibiotic. | viridenomycin, a new crystalline antibiotic, was isolated from the culture broth of streptomyces viridochromogenes strain no. t-24146. viridenomycin is a weakly acidic and lipophilic substance, which exhibits a strong absorption maximum at 310 nm and shows strong activity against trichomonas vaginalis and gram-positive bacteria. | 1975 | 1079209 |
| [studies on trichomonas vaginalis in urological fields. v11. the experimental infection of trichomonas vaginalis in human urethra (author's transl)]. | | 1975 | 1079286 |
| [studies on trichomonas vaginalis in urological fields. viii. hydratase of trichomonas vaginalis (author's transl)]. | | 1975 | 1079287 |
| [studies on trichomonas vaginalis in urological fields. ix. aldolase, ldh and alcohol dehydrogenase of trichomanas vaginalis (author's transl)]. | | 1975 | 1079288 |
| treatment of vaginal discharge with yoghurt. | a preliminary trial was conducted, using yoghurt to assess its potential for the management of vaginal discharge. the results were encouraging in non-specific vaginal discharge and warrant further investigation. the treatment was ineffective in reducing trichomonas vaginalis infestation, and in this condition no further investigation is warranted. | 1975 | 1079635 |
| [atypical phagocytosis of starch grains by trichomonas vaginalis]. | | 1975 | 1079667 |
| [correlation between trichomonadosis in newborn infants and fetal presentation]. | | 1975 | 1079668 |
| [effect of obstetric procedures on infection of newborn infants with trichomonas vaginalis during delivery]. | | 1975 | 1079669 |
| [immature and premature effluence of amniotic fluid and trichomonadosis in newborn infants]. | | 1975 | 1079670 |
| [incidence of trichomonas vaginalis infections in newborn infants in the course of prolonged delivery]. | | 1975 | 1079671 |
| [cesarean section and occurrence of trichomonas vaginalis in newborn infants]. | | 1975 | 1079672 |
| some characteristics of women with abnormal cervical cytological findings. | | 1975 | 1079953 |
| [biomorphological changes in the vaginal part of the uterus in a guinea pig as a result of trichomonas vaginalis infection]. | | 1975 | 1079989 |
| letter: neonatal haemophilus influenzae infection. | | 1975 | 1080010 |
| epidemiology and aetiology of cancer of the uterine cervix including the detection of carcinogenic n-nitrosamines in the human vaginal vault. | cancer of the uterine cervix occurs with high frequency in black females of several populations of southern africa. it accounts for 40-50% of all cancers in black females in the johannesburg area and for over 40% of those in women in the rural lowveld area of the transvaal. the aetiology of this cancer has several distinct features, almost all of which concern some or other aspect of coitus. age at first coitus and at first marriage, and promiscuity, are very strongly associated with the develop ... | 1975 | 1080296 |
| electron microscopy of trichomonas vaginalis donné: interaction with vaginal epithelium in human trichomoniasis. | light and electron microscopic examination of portio biopsies from eleven patients with trichomoniasis vaginalis revealed in four patients clusters of cells of t. vaginalis (t. vag.) which were attached to the vaginal mucosa. the minimum gap between adjacent trichomonad cells was the size of gap junctions (2 nm). cells of t. vag. invaded superficially located epithelial cells but did not penetrate to the deeper cell layers of the epithelium. the latter, however, were frequently infiltrated with ... | 1975 | 1080326 |
| an investigation into the effect of metronidazole on the morphology of trichomonas vaginalis. | | 1975 | 1080756 |
| the effect of metronidazole and nitrofurans on the morphology of trichomonas vaginalis. | | 1975 | 1080758 |
| [current concepts of the morphology and some biochemical properties of vaginal trichomonads]. | | 1975 | 1080935 |
| trichomonas vaginalis in a perinephric abscess. a case report. | a patient with chronic vulvo-vaginitis due to trichomonas vaginalis, and obstructive uropathy associated with renal calculi, developed a perinephric abscess following trauma incurred in a motorcycle accident. t. vaginalis was seen on smear and cultured from the purulent drainage from the perinephric abscess. although t. vaginalis is commonly pathogenic only to the lower genito-urinary system, the upper urinary tract may very rarely be involved by ascending infection. if this protozoan spreads to ... | 1975 | 1081348 |
| [condensation products of nitrated heterocyclic aldehydes with oxo-cyclopentathiophenes and oxo-tetrahydroquinolines (author's transl)]. | | 1975 | 1081385 |
| antitrichomonal antibody in the vaginal secretions of women infected with t. vaginalis. | vaginal secretions from 508 women were examined for evidence of infection by trichomonas vaginalis, and for antibodies directed against this organism; 42 women (8-3 per cent.) were found to be infected. secretions from 29 of these women were assayed and antibody apparently directed against t. vaginalis was found in 22 (76 per cent.) of them. eight out of nineteen secretions (42 per cent.) from apparently uninfected women also contained antibody. amongst the infected women, no correlation could b ... | 1975 | 1081423 |
| use of solid medium techniques to evaluate factors affecting the ability of trichomonas vaginalis to survive freezing. | | 1975 | 1081590 |
| the ultrastructure of trichomonas vaginalis donné before and after transfer from vaginal secretion to diamonds medium. | cell of trichomonas vaginalis (t. vag.) obtained from five patients with severe trichomoniasis were fixed for electron microscopy directly in the vaginal fluid. samples of the same material from three of the patients was inoculated into diamonds medium and propagated for 3-6 weeks. during the first 3-4 weeks in vitro the fine structure of all cells was changed. the shape of the nucleus, the size of the golgi apparatus and adjacent vesicles, the fine structure of the chromatic granules, and the m ... | 1975 | 1081812 |
| [ultrastructure and certain biological properties of trichomonas vaginalis (electron-microscopic study)]. | | 1975 | 1083148 |
| study of female babies of women entering confinement with vaginal trichomoniasis. | a series of 868 women in the last 4 weeks of pregnancy were examined for the presence of t. vaginalis by direct microscopy of freshly prepared wet films and by three culture methods; 32 (3-7 per cent.) were found to give positive results. fourteen of the mothers with trichomoniasis at confinement had female babies, and these, together with a matching fourteen controls, were examined on three occasions by identical methods and within 21 days of birth. no baby gave positive results. on statistical ... | 1976 | 1083275 |
| [study of the effect of the enzyme hyaluronidase on the pathomorphological changes in certain internal organs in white mice infected intraperitoneally with tr. vaginalis]. | the authors injected daily a dose of 5 l hyaluronidase diluted in 0,5 ml of saline, in 25 out of 50 white mice, contaminated with tr. vaginalis intraperitonealy. the remaining 25 mice formed the control group and were injected only with saline. the administration was made intraperitonealy. an equal number of mice from both groups were killed on the 30th and 40th day of contamination and the macroscopic changes in the abdominal cavity were examined. histological examinations of liver, spleen and ... | 1975 | 1083339 |
| uptake of metronidazole and its effect on viability in trichomonads and entamoeba invadens under anaerobic and aerobic conditions. | [(14)c]metronidazole used at the chemotherapeutic concentration of 10 mug/ml is taken up rapidly by the anaerobic protozoa tritrichomonas foetus, trichomonas vaginalis, and entamoeba invadens kept under anaerobic conditions. it can be calculated that within 30 to 60 min the intracellular concentration of the label is 50 to 100 times higher than in the medium. the presence of air markedly suppresses the uptake in the trichomonads and abolishes it in e. invadens. the suppression disappears after a ... | 1976 | 1083712 |
| the size, density, and relative area of chromatic granules ("hydrogenosomes") in trichomonas vaginalis donne from cultures in logarithmic and stationary growth. | electron micrographs of trichomonas vaginalis cells were examined morphometrically by means of an electronic image analyser. cells from cultures in logarithmic growth contained smaller chromatic granules ("hydrogenosomes") and a higher proportion of sausage- or dumb-bell-shaped granules than did cells in stationary growth. these findings support the view that chromatic granules replicate by division of pre-existing granules and that this involves elongation and attenuation of their mid-region. t ... | 1976 | 1083767 |
| [trichomoniasis in girls]. | | 1976 | 1083971 |
| in vitro effect of metronidazole on the ultrastructure of trichomonas vaginalis donné. | the effect of metronidazole on the growth and fine structure of exponeentially growing cells of trichomonas vaginalis was examined. cell division stopped about one hour after the addition of 1-4 mug/ml of metronidazole, and the cells were apparently arrested in the interphase. one to two hours after the addition of metronidazole, the movement of flagella and of the undulating membrane had decreased, but cell death had not occurred until 7-8 hours later. the fine structure of the cytoplasm was ch ... | 1976 | 1084098 |
| [epidemiological study of trichomonas vaginitis in umbria]. | | 1975 | 1084133 |
| [role of exogenous factors in the development of intraepithelial lesions of the uterine cervix (author's transl)]. | | 1976 | 1084730 |
| [the action of prostatic secretion on trichomonas vaginalis (author's transl)]. | | 1976 | 1085197 |
| [pathogenic action and sero-immunologic phenomena of trichomonas vaginalis]. | trichomonas vaginalis is a frequent parasite of the urogenital system of the human been. the pathological manifestations are different with each strain. these variations of the pathogenic action of the parasite are found in the study of the experimental pathogenic action of the animal and in vitro on cell culture. the sero-immunological phenomens which lead to the presence of the parasite are not completely known. some technics was proposed for the diagnosis. their practical utilisation is not c ... | 1976 | 1085306 |
| new data on the mechanism and speed of action of nitroimidazoles on prokaryota and eukaryota with and without mitochondria. | the spectrum of action of nitroimidazoles ranges from anaerobic bacteria to aerobic bacteria which are also capable of growth, although sometimes with difficulty, in anaerobic atmosphere and to protozoa without and with mitochondria; in the latter case the anti-protozoal activity depends on the importance of the extramitochondrial enzymes which respond to nitroimidazoles. the more anaerobic the organisms, the greater their sensitivity. in the most sensitive protozoa, the trichomonads, most of th ... | 1976 | 1085631 |
| [frequency of trichomonas vaginalis infection in apparently healthy chilean women (1975) (author's transl)]. | | 1976 | 1085634 |
| [prevalence of trichomonas vaginalis infection in men from the city of santiago (chile, 1975) (author's transl)]. | | 1976 | 1085635 |
| application of wish cell cultures to produce large populations of vaginal trichomonads. | | 1976 | 1085652 |
| [pathology and clinical aspects of human trichomonas vaginalis infections]. | | 1976 | 1085769 |
| colonial morphology of trichomonas vaginalis in agar. | | 1976 | 1086354 |
| may trichomonas vaginalis provoke conjunctivitis? | in the world literature we have found descriptions of five cases of trichomonas vaginalis in the conjunctiva. conjunctival swabs taken from 122 patients with conjunctivitis or keratitis revealed no flagellate micro-organisms on phase-contrast microscopy and culture. neither did conjunctival swabs from 272 newborn infants, in spite of the fact that 3.7 per cent of their mothers had trichomonas in the vagina. trichomonas vaginalis is hardly likely to be responsible for conjunctivitis. | 1976 | 1086574 |
| [evaluation of the agglutinating action of lectins on trichomonas vaginalis by means of different methods]. | trichomonas vaginalis (strain fc) are specifically agglutinated by con a and pha-p but not by wga. the techniques used gave basically the same results however the agglutination in plates has the advantage of a good sensitivity and a greater simplicity of execution. | 1975 | 1086810 |
| [in vitro sensitivity of trichomonas vaginalis to canestan (clotrimazole)]. | | 1976 | 1087423 |
| sensitivity of trichomonas vaginalis to metronidazole, tinidazole, and nifuratel in vitro. | prompted by the sensitivity of trichomonads to metronidazole and nifuratel in clinical practice, a study was conducted in 1971-1972 of 63 consecutive strains of trichomonas vaginalis isolated from women with clinically refractory vaginal discharge. their susceptibility to metronidazole, tinidazole, and nifuratel was tested, using a serial tube dilution technique. the minimum concentrations which in 48 hrs caused immobilization and lysis of trichomonads cultured in diamond's medium was assessed. ... | 1976 | 1087577 |
| the effect of chlorine and its compounds used for disinfection of water on trichomonas vaginalis. | | 1976 | 1087786 |
| [vaginal flora in women from gevgelija]. | the author gives data on the vaginal flora of women aged 20--64 in the commune of gevgelia obtained in the course of an early mass detection of the carcinoma of the uterine cervix in this area. the action covered 70.5% of women from urban areas and 85.3% of women from rural areas. the microbiological analysis of vaginal flora was made in two ways: first, by taking smears and by vital staining and classifying them after jirovec, peter, and malik; another preparation was sent to the cytologist and ... | 1976 | 1087944 |
| [immobile and circular forms of trichomonas vaginalis]. | | 1976 | 1088186 |
| [quantitative study on the "in-vitro" trichomonicide effect of tinidazole (beta-1-ethyl-sulfonyl-ethyl 2 methyl-5-nitroimidazole) on recently isolated strains of trichomonas vaginalis]. | | 1976 | 1088519 |
| [the influence of antimetabolites on trichomonas vaginalis as an experimental model]. | the present study was concerned with the relationship between antimetabolites and trichomonas vaginalis. in all of the strains (with p-nitrobenzylether of n-acetyldiiodtryrosine) tested, the growth of trichomonas vaginalis was identical to that of the control series at concentrations up to 2 mg/ml. at higher concentrations a decrease in multiplication was noted. in the experimental series with antitrypsin, from 1 mg/ml produced an inhibiting effect upon the trichomonas population. further invest ... | 1976 | 1088559 |
| [value of the modified roiron medium for the simultaneous detection of urogenital tract infection by trichomonas vaginalis and yeast-like fungi in humans]. | | 1976 | 1088589 |
| the role of fomites in the transmission of vaginitis. | a role for fomites such as toilet seats in the transmission of vaginitis has never been proved or disproved. a compilation of clinical data from a university community showed that the organisms found in vaginal cultures of patients with vaginitis were, in order of frequency. candida albicans, escherichia coli, beta-hemolytic streptococci, hemophilus vaginalis and trichomonas vaginalis. in a concurrent bacteriologic survey of washroom fixtures, staphylococci and other micrococci were isolated mos ... | 1975 | 1092449 |
| non-specific urethritis and the tetracyclines. | the possible aetiological factors in non-gonococcal and non-specific urethritis are reviewed. the response of nsu to various courses of different tetracycline drugs is assessed. prolonged courses of treatment did not give better results than shorter courses. when reviewing the infective aetiology of non-gonococcal urethritis, it was noted that more than one organism (or potential pathogen) would be present in many cases. it is therefore surmised that there may be at times a mixed aetiology and a ... | 1975 | 1095144 |
| [bacteriological and parasitological investigations in public indoor swimming baths (author's transl)]. | the importance of the public swimming bath for the dissemination of trichomonas vaginalis is disputed. 30 samples, each of 250 ml bath water from four indoor swimming baths, were examined for trichomonads. all the samples were negative. 218 smears taken from the wet places on the heated benches and other seating accommodation in these swimming baths were cultured for trichomonads and bacteria. trichomonas vaginalis could not be demonstrated. fecal organisms were found in 56 places, antibiotic-se ... | 1975 | 1098331 |
| microbial flora of the lower genital tract during pregnancy: relationship to morbidity. | nineteen genera and groups of micro-organisms were isolated from the lower genital tract of 280 women at their first antenatal visit. chlamydia, viruses, and t-strain mycoplasmas were not sought, and only routine methods of anaerobic culture were used. growth was recorded as scanty, moderate or heavy. the population studied was grouped according to age, parity, gestational stage at booking, presence and degree of severity of lower genital tract morbidity, past history of vulvovaginitis, and susp ... | 1975 | 1100681 |
| [study of the direct immunofluorescence method for the differentiation of trichomonad serotypes]. | it is possible to differentiate the serotypes of trichomonas vaginalis by the direct immunofluorescent method using the tupe-specific antisera labelled with fluorescein-isot-hiocyanate. the most decisive factor in expressing the degree of induced fluorescence is the serotype of the protozoa. evans blue, which has an intensive red fluorescence, totally eliminates the green autofluorescence of t. vaginalis and does not influence the induced specific fluorescence. | 1975 | 1105317 |
| [a new and simple method for the treatment of trichomonas vaginalis infestation (author's transl)]. | | 1975 | 1105869 |
| [biological and clinical effects of methylpartricin on trichomonas vaginalis and candida albicans]. | | 1975 | 1107887 |
| [preliminary results of the use of an antimycotic drug, clotrimazole (bis-phenyl-(2-chlorophenyl)-1-imidazoly-methane: bay b 5097) in local administration for therapy of vaginitis caused by candida albicans and by trichomonas vaginalis]. | | 1975 | 1134683 |
| [incidence of trichomonas vaginalis infections in women in poland]. | | 1975 | 1144184 |
| [treatment of trichomonas vaginalis with a single dose of metronidazole (flagyl, trichomol), tinidazole (fasigyn)]. | | 1975 | 1145795 |
| [new acquisitions in the therapy of trichomonas vaginalis vaginitis]. | | 1975 | 1166170 |
| a method for the diagnosis of trichomonas vaginalis using acridine orange. | | 1975 | 1185441 |
| [intravaginal infection of the rat with trichomonas vaginalis and candida albicans. an experimental model for chemotherapy (author's transl)]. | ovariectomised and oestrogen premedicated rats were infected intravaginally, with first c. albicans and then with t. vaginalis. under these conditions infections with t. vaginalis could be established with more reliability than when using axenically-cultivated t. vaginalis alone. this mode of infection is easily reproduced, and it allows the performance of chemotherapeutic tests on small groups of laboratory animals. such tests were carried out with metronidazole, tinidazole and nifuratel. | 1975 | 1216328 |
| single dose treatment of trichomonas vaginalis with tinidazole (fasigyn). | | 1975 | 1224628 |
| treatment of trichomonas vaginitis with a single dose of tinidazole. | trichomonas vaginalis is a flagellate protozoon which in women commonly causes vaginal itching; burning, and a frothy, offensive and seropurulent yellowish discharge. incidence of infection in women varies from 13 to 60%, and is highest during pregnancy because of excess estrogens and in women with poor hygiene or with vaginitis. in men, the incidence ranges from 9 to 37% of persons with urethral discharge. this study presents the results of the use of a single dose treatment of trichomonas va ... | 1975 | 1236491 |
| [early identification of cancer through vaginal cytology in a venereal disease clinic]. | 100 women, routinely and regularly examined in a venereal disease clinic, have been investigated using papanicolaou smears of the uterine cervix for. 1. papanicolaou group, 2. trichomonas infection, 3. assessment of vaginal microbiology. a group iii was determined in 11, a group iv/v in 2 women. trichomonas vaginalis was present in 60% of the cases. only 9% of the smears showed normal döderlein bacteria; 91% contained mixed bacteria. the findings are compared with a control group and are discuss ... | 1975 | 1243854 |
| effect of a phorbol ester on basic surface properties of trichomonads. | the effect of nanomolar concentrations of 12-o-tetradecanoilphorbol-13-acetate (tpa) on the cell surface of the urogenital parasitic protozoa trichomonas vaginalis and tritrichomonas foetus was evaluated by means of measurements of the parasites' surface tension, electrokinesis, lectin agglutination tests, and adhesion to inert substrates. tpa-treated parasites had their adhesion increased to both plastic and glass substrates. this was accompanied by increases in the parasites' net negative surf ... | 1992 | 1284779 |
| antibacterial, antimycotic and trichomonicidal activity of a new nitroimidazole (eu 11100). | the antimicrobial profile of a new nitroimidazole derivative (5-nitro-1-methyl-imidazolyl-2-hydroxy-3 terbutylphenyl carbinol) has been studied. the in vitro activity of the new molecule has been evaluated against both aerobic and anaerobic bacteria, trichomonas vaginalis, and mycetes, under suitable experimental conditions. the new compound was compared with ampicillin against aerobic bacteria; with metronidazole against anaerobic bacteria, lactobacilli and t. vaginalis; with nistatin and econa ... | 1992 | 1287136 |
| activity assays of thiadiazine derivatives on trichomonas vaginalis and amastigote forms of trypanosoma cruzi. | eight thiadiazine 1,1-dioxide derivatives were evaluated for antitrichomonal and antitrypanosomal activities. in vivo tests were performed on a murine model for trichomoniasis standardized in our laboratory. the capacity of compounds to clear visceral lesions in experimentally infected animals as well as their effects on the mortality time of mice were used as criteria for activity. one of the thiadiazines (compound 7b) showed an efficacy similar to that obtained with the reference drug metronid ... | 1992 | 1288970 |
| lysis of erythrocytes by trichomonas vaginalis. | the in vitro hemolytic activity of 4 isolates of trichomonas vaginalis was investigated. repetitive hemolysis assays of any one isolate showed cyclical fluctuations in hemolytic activity, varying over 24 hr of continuous culture. maximal hemolytic activity was detected using trichomonads in the lag phase of the growth cycle. investigations showed that hemolysis was a contact-dependent phenomenon and microscopic investigation of samples showed a significant correlation between hemolysis and attac ... | 1992 | 1290802 |
| energy metabolism of ancestral eukaryotes: a hypothesis based on the biochemistry of amitochondriate parasitic protists. | parasitic amitochondriate protists, representatives of early branches of eukaryote evolution, differ considerably in their central, energy metabolism from mitochondrion-bearing cells. these differences are: significant metabolic functions of inorganic pyrophosphate, major role of iron-sulfur proteins in key metabolic steps and in hydrogenosome-bearing organisms the disposal of electrons by h2 formation. cytochrome-mediated electron transport and electron transport-linked phosphorylation are abse ... | 1992 | 1292665 |
| [comparative antigen analysis of trichomonas vaginalis by enzyme-linked immunoelectrotransfer blot technique]. | analysis of six isolates of trichomonas vaginalis was carried out with sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) and enzyme-linked immunoelectrotransfer blot (eitb). trichloroacetic acid-treated antigens of the 6 isolates revealed 25 protein profiles ranging 12-170 kda of molecular weight in sds-page. in eitb, the specific immunogenic bands were visualized at 51 kda and 96 kda when hy-1 antigen was probed with different mice sera immunized with 6 isolates of t. vaginal ... | 1992 | 1297423 |
| risk factors for hiv infection in gynaecological inpatients in dar es salaam, tanzania, 1988-1990. | a prevalence of 12.8% for anti-hiv-1 and a prevalence of 16.8% for anti-syphilis antibodies was found in 359 gynaecological inpatients admitted in the department of gynaecology and obstetrics, muhimbili university college of health sciences from 1988 to 1990. the highest hiv prevalence (17.3%) was observed in the youngest age group (14-20 years), whereas the highest syphilis prevalence (22.2%) was found in the oldest age group (> 45 years). infections with hiv and syphilis were both significantl ... | 1992 | 1298634 |
| effect of estrogens on the adhesion of trichomonas vaginalis to epithelial cells in vitro. | 1. to further characterize the basic aspects of parasite-cell interaction, untreated and hormone-treated madin-darby canine kidney (mdck) cells were allowed to interact with t. vaginalis. 2. among the six hormones assayed, alpha-estradiol caused mdck cells to become highly adhesive to t. vaginalis. increases in parasite adhesion of 83% and 68% were obtained by previous incubation of the epithelial monolayers for 18 h with 1 ng/ml alpha-estradiol and 10 ng/ml 17-beta-estradiol, respectively. 3. t ... | 1992 | 1304948 |
| interactions between trichomonas vaginalis and vaginal flora in a mouse model. | to study the role of vaginal flora and ph in the pathogenesis of trichomonas vaginalis, an intravaginal mouse model of infection was established. by employing this model, the vaginal flora and ph of mice could be monitored for changes caused by the parasite. as a baseline, the endemic vaginal flora of balb/c mice was examined first and found to consist mainly of staphylococcus aureus and enterococcus species (32-76%). lactobacilli and enteric bacilli were moderate (16-32%) in their frequency of ... | 1992 | 1310732 |
| iron regulates growth of trichomonas vaginalis and the expression of immunogenic trichomonad proteins. | iron is an essential nutrient for trichomonas vaginalis and is acquired via highly specific receptor-mediated mechanisms from the host. responses of t. vaginalis to conditions of iron limitation or iron excess were analysed in order to determine whether iron levels in the growth medium regulate certain properties of the parasite. when compared with organisms grown in excess iron, iron limitation resulted in greater than or equal to 80% lower rates of protein synthesis and greater than or equal t ... | 1992 | 1310792 |
| the pathway of arginine catabolism in giardia intestinalis. | in giardia intestinalis, arginine is catabolised by the arginine dihydrolase pathway. the enzymes of the pathway (arginine deiminase, ornithine transcarbamoylase and carbamate kinase) were investigated and their basic kinetic parameters determined. the specific activity of arginine deiminase was 270 +/- 23 nmol min-1 (mg protein)-1; ornithine transcarbamoylase, in the direction of citrulline utilisation 170 +/- 22 nmol min-1 (mg protein)-1, and in the direction of ornithine utilisation 2100 +/- ... | 1992 | 1314332 |
| human papillomavirus (hpv) infection, hiv infection and cervical cancer in tanzania, east africa. | the presence of hpv-dna was determined in tumor biopsies of cervical-cancer patients and in cervical swabs of non-cancer patients from tanzania, east africa, by southern blot hybridization and/or pcr. hpv types 16 and 18 were detected in 38% and 32%, respectively, of 50 cervical-carcinoma biopsies. a consensus primer pcr capable of detecting a broad spectrum of hpv types revealed the presence of hpv-dna in 59% of 359 cervical swabs of non-cancer patients. type-specific pcr showed that types 16 a ... | 1992 | 1318265 |
| trichomonas vaginalis (tv) and human papillomavirus (hpv) infection and the incidence of cervical intraepithelial neoplasia (cin) grade iii. | the temporal relationship between cervical infection with trichomonas vaginalis (tv) or human papillomavirus (hpv) and the incidence rate of cervical intraepithelial neoplasia grade three (cin iii) was examined in a cohort of 43,016 norwegian women. from 1980 to 1989, a cervico-vaginal infection from tv and hpv was diagnosed cytologically in 988 and 678 women, respectively. during the 181,240 person-years of observation, 440 cases of cin iii/cervical cancer developed. the age-adjusted incidence ... | 1992 | 1319218 |
| rapid inactivation of infectious pathogens by chlorhexidine-coated gloves. | gloves containing chlorhexidine gluconate in an instant-release matrix on their inner surface (chg gloves) were tested to determine their ability to rapidly inactivate infectious pathogens that may permeate or leak through the latex surface. | 1992 | 1325495 |
| cytologic evidence of the association of different infective lesions with dysplastic changes in the uterine cervix. | cervical smears from 4055 women were examined and classified as per who criteria. 873 (21.53%) smears revealed dysplastic changes. the dysplastic smears were further examined cytologically for the presence of chlamydia trachomatis, herpes simplex virus type-2, human papilloma virus, trichomonas vaginalis and candida albicans. chlamydia was found to be the commonest micro-organism associated with cervical dysplasia followed by herpes simplex virus type-2 and human papilloma virus. the association ... | 1992 | 1336729 |
| molecular analysis of trichomonas vaginalis surface protein repertoires. | | 1992 | 1341642 |
| vaginal microbial flora as a cofactor in the pathogenesis of uterine cervical intraepithelial neoplasia. | the vaginal microbial flora of 106 women with histopathologically confirmed cervical intraepithelial neoplasia and 79 women without disease, was evaluated for gardnerella vaginalis, trichomonas vaginalis, candida albicans and other yeasts. flora morphology was assessed by gram staining of secretions. cervical cultures were examined for herpes simplex virus, cytomegalovirus and neisseria gonorrhoeae. chlamydia trachomatis antigens in cervical secretions were detected by enzyme immunoassay. human ... | 1992 | 1351005 |
| is trichomoniasis often associated with bacterial vaginosis in pregnant adolescents? | the same criteria for identifying bacterial vaginosis are often present in women with trichomoniasis. these criteria include elevated vaginal ph, vaginal odor, homogeneous discharge, increased anaerobic bacteriologic vaginal flora, and elevated levels of bacterial enzymes. clinically mixed vaginal infections occur, and because the treatment for these two conditions can be different, it is important to distinguish between them. trichomoniasis can interfere with a gram stain diagnosis or the proli ... | 1992 | 1372472 |
| characteristics of three vaginal flora patterns assessed by gram stain among pregnant women. vaginal infections and prematurity study group. | this study was undertaken to define the characteristics and persistence of vaginal flora in 7918 pregnant women at 23 to 26 weeks' gestation. vaginal smears were categorized as normal (predominant lactobacilli), intermediate (reduced lactobacilli), or positive for bacterial vaginosis. the women with normal flora were least likely to have elevated vaginal ph, amine odor, milky discharge, or colonization by gardnerella, bacteroides, or genital mycoplasmas. women with intermediate vaginal flora had ... | 1992 | 1372474 |
| reduced transcription of the ferredoxin gene in metronidazole-resistant trichomonas vaginalis. | metronidazole [1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole] is used to treat infections caused by trichomonas vaginalis, a sexually transmitted human parasite. this drug is administered in an inactive form and is reduced to its cytotoxic form within the hydrogenosome, an unusual organelle found in trichomonads. metronidazole reduction occurs via ferredoxin-mediated electron transport. we have investigated the role of ferredoxin in metronidazole resistance. immunoblot analysis of drug-resistant ... | 1992 | 1374901 |
| phenotypic variation of surface antigenic determinants in trichomonas vaginalis detected by monoclonal antibodies. | we produced a large panel of murine monoclonal antibodies against surface determinants of trichomonas vaginalis using the hybridoma technique. an immunoenzymatic technique (e.l.i.s.a.) was used to screen positive hybrid cells producing specific antibodies against the protozoan surface. eleven monoclonal antibodies (mabs) out of seventy-seven positives were further characterized. we tested antibody reactivity in order to investigate the antigenic variance among 13 different strains of trichomonas ... | 1992 | 1380113 |
| [preparation and identification of anti-trichomonas vaginalis monoclonal antibodies]. | hybridomas producing monoclonal antibodies (mcab) directed against trichomonas vaginalis have been produced by fusing nsi myeloma cells with spleen cells of balb/c mice immunized with trichomonas vaginalis. ifa technique was used to test the binding activity of four mcabs produced. the mcab belonged to the igg subtypes igg1 (2a2, 2a4 mcab), igg3 (2h9 mcab) and igg 2b (2a12 mcab). three mcabs, designated 2a2, 2a4, 2a12, reacted with a surface membrane component of live trichomonas vaginalis. one ... | 1992 | 1394911 |
| protozoan infections and hiv-1 infection: a review. | reactivation of latent infection is the principal mechanism relating toxoplasma gondii and pneumocystis carinii to hiv. less common is reactivation in leishmania donovani, trypanosoma cruzi, and microsporidian infections. an impaired primary immune response occurs in all these infections, and also with cryptosporidium and isospora belli. association of hiv infection with gut parasites including giardia lamblia and entamoeba histolytica, and also with trichomonas vaginalis infection is likely to ... | 1992 | 1396192 |
| treatment of symptomatic trichomoniasis among adult women using oral nitroimidazoles. | successful treatment of infections with trichomonas vaginalis (tv) is difficult because of many confounding factors such as poor abstinence from sex during chemotherapy, lack of standardised chemotherapy, difficulties in understanding transmission patterns and low detection rates among infected individuals. the purpose of this study was to establish the present efficacy of the available drugs at their recommended single or double dosages for kenya. adult symptomatic females (age 17-39 years) wit ... | 1992 | 1396198 |
| inflammation on the cervical papanicolaou smear: the predictive value for infection in asymptomatic women. | the clinical significance of inflammation on the cervical papanicolaou (pap) smear of asymptomatic women is unknown. this study assessed the possible association between inflammation on pap smears with the presence of cervical/vaginal pathogens. | 1992 | 1397815 |
| a novel neutrophil-activating factor released by trichomonas vaginalis. | we have investigated the effects of a novel neutrophil-activating factor released by trichomonas vaginalis (tv-naf) on neutrophil chemotaxis. tv-naf was present in the supernatant from 10(7) t. vaginalis (stv) cultured in 1 ml of serum-free hanks' balanced salt solution (hbss) at 37 degrees c for 30 min. with a multichamber chemotactic assay, we found that there were 112 +/- 15 migrated neutrophils (mean +/- standard deviation, n = 7) for stv and 11 +/- 4 for hbss per high-power field (x 400). s ... | 1992 | 1398962 |
| beta-succinyl-coenzyme a synthetase from trichomonas vaginalis is a soluble hydrogenosomal protein with an amino-terminal sequence that resembles mitochondrial presequences. | we describe studies directed toward understanding the biogenesis and origin of the hydrogenosome, an unusual organelle found exclusively in certain anaerobic eukaryotes that lack mitochondria. hydrogenosomes are involved in fermentative carbohydrate metabolism and are proposed to have arisen through conversion of mitochondria or via endosymbiosis with an anaerobic bacterium. we cloned a gene encoding the beta subunit of the hydrogenosomal protein succinyl-coenzyme a synthetase (beta-scs) and iso ... | 1992 | 1400232 |
| the plastic envelope method, a simplified technique for culture diagnosis of trichomoniasis. | although culture of trichomonas vaginalis is more sensitive than wet mounts in the diagnosis of trichomoniasis, the lack of convenience of culture prevents it from being widely used. to improve the acceptability of diagnosis by culture, a plastic envelope method (pem) was devised. pem permits both immediate examination and culture in one self-contained system. the medium consists of dry ingredients that are reconstituted with water before use. the effectiveness of immediate examinations by pem w ... | 1992 | 1400989 |
| the incidence of trichomonas vaginalis in chronic prostatitis patients determined by culture using a newly modified liquid medium. | | 1992 | 1402043 |
| cell surface saccharide differences in drug-susceptible and drug-resistant strains of trichomonas vaginalis. | surface carbohydrates of drug-resistant and drug-susceptible strains of trichomonas vaginalis were analysed using lectins. the presence of d-galnac, d-gal and mannose-like residues was detected in t. vaginalis. marked differences in exposed surface carbohydrates were documented, e.g. wheat germ agglutinin (wga) selectively agglutinated the drug-susceptible strain whereas drug-resistant parasites reacted preferentially with concanavalin a (con a). in drug-resistant, but not in drug-susceptible st ... | 1992 | 1406344 |
| prevalence of sexually transmitted disease infection in women alleging rape. | during a 2-year period ending in october, 1989, 110 women who claimed to have been raped were treated at the sexually transmitted disease clinic at birmingham general hospital. a total of 22 sexually transmitted infections were found in 14 (13%) women, of which chlamydia trachomatis (in 8%) and trichomonas vaginalis (in 6%) were the most frequently found pathogens. in none of these patients was it possible to determine whether infection resulted from rape or from voluntary intercourse with anoth ... | 1992 | 1411849 |
| synthesis and antiprotozoal properties of 1,2,6-thiadiazine 1,1-dioxide derivatives. | the synthesis and spectroscopical data of 1,2,6-thiadiazine 1,1-dioxides, designed as antiprotozoal agents, are reported. the in vitro trichomonacidal and trypanocidal activities of new compounds and their precursors were evaluated against trichomonas vaginalis and trypanosoma cruzi. the chemoprophylactic activity on mice treated with blood infected with t. cruzi and their mortality percentage were tested. compounds 2 and 8b show a higher chemoprophylactic activity and lower mortality percentage ... | 1992 | 1417459 |
| management of chronic urethral symptoms in men. | we describe 20 men who were referred because of chronic urogenital symptoms. they had been previously seen by zero to six physicians (mean, 1.8 physicians) and had been treated with zero to five courses of antimicrobial agents (mean, 2.4 courses) without relief of their symptoms. results of physical examinations of all patients were normal. an extensive evaluation failed to reveal any objective evidence of urethral inflammation. cultures for neisseria gonorrhoeae, chlamydia trachomatis, ureaplas ... | 1992 | 1420690 |