| evaluation of endomyocardial biopsy in the diagnosis of cardiac rejection. a study using bioptome samples of formalin-fixed tissue. | the reliability of endomyocardial bioptome samples in detecting cardiac rejection was assessed in 26 formalin-fixed previously transplanted hearts. thirteen human donor hearts (mean postoperative survival 128 days) and 13 baboon donor hearts (mean survival 16.5 days) were studied. twenty samples were taken under direct vision from the endomyocardium of each heart with an olympus bioptome catheter. a total of 397 tissue samples was examined "blindly" histologically (177 human and 220 baboon). the ... | 1978 | 97824 |
| genetics of the idiotype of strain akr antibodies to group a streptococcal carbohydrate; further evidence for a low degree of homology in the vh chromosomal region. | a new vh gene is described which governs the expression of idiotypes associated with the antibody response of strain akr mice to group a streptococcal carbohydrate (a-cho). this vh gene, termed achd, is identified using guinea pig antisera to a pool of strain akr antibodies to a-cho. the genetic polymorphism is revealed by quantitative differences in idiotype expression between different inbred strains. in recombinant inbred strains linkage to the ig-1d allotype allele of strain akr is demonstr ... | 1978 | 97871 |
| [immunological study of cellular components of pseudomonas aeruginosa. iv. fractionation of pseudomonas aeruginosa mucus by diafiltration and biological properties of isolated fractions]. | in fractionation of pseudomonas aeruginosa mucus (strains no. 8 and 1463) by means of diafiltration on the system of membranes diaflo xm-300, xm-100a, pm-30, and pm-10 there was obtained a successive series of fractions differing by the molecular weight and chemical composition. according to the results of gel chromatography fractions with the mol wt of 100000 dalton and over apparently represented protein-polysaccharide components of mucus in the form of complexes; fractions with the mol wt of ... | 1978 | 97882 |
| [prospects for the use of blood substitutes made in the ussr with the expired date of validity]. | as revealed, blood substitutes--aminopeptide, caseine hydrolysate, and hydrolysine with the expired date of validity could be used as the basis of nutrient media for the cultivation of bacteria. bacterial growth proved to be the optimum in addition to the blood substitutes of a 0.25--0.5% of yeast extract. | 1978 | 97885 |
| [enzyme-histochemical behaviour of the tanycyte ependyma in the iii. ventricle of the rat with thiamin deficiency (author's transl)]. | the influence of experimental thiamine deficiency in rats on enzyme-histochemical parameters was carried out in the diencephalon. the degree of thiamine deficiency was measured by the activity coefficient of transketolase in the red blood cells. the alpha-etk of thiamine deficient animals was 1,45 +/- 0,36, of equal-fed animals 1,04 +/- 0.04 and of control animals 1,08 +/- 0,04. we got the following results: lactatdehydrogenase, acid phosphatases and thiamine pyrophosphatase did not indicate any ... | 1978 | 97912 |
| placental permeability in the sheep. | the transplacental flux of different radiolabelled substances was measured, according to fick's principle, in chronically catheterised pregnant sheep (124 to 143 days of gestation). knowing the uterine blood flow, it was possible to calculate the net flux and derive a permeability coefficient, k. with 14c erythritol, k soon reaches its ultimate value, thus suggesting there is only one rate-limiting step to transfer and no significant middle compartment in the sheep placenta. the comparison of fe ... | 1977 | 98093 |
| [food additives and their possible genetic toxicity; microbiological determination]. | in the present work we intend to find an accurat methodology to establish in an easy way the mutagenic potential of drugs employed as food additives. for that purpose we first selected a microbiological system for performing this assay. the method assayed consisted of investigating the effect exerted on genetic recombination by the following chemical agents: chloroacetic acid, iodoacetic acid, sorbic acid, potassium metabisulfite, sodium nitrite, auramine and erythrossine. the activity of these ... | 1977 | 98122 |
| studies on the pathogenesis of hemorrhagic enteritis of turkeys. | the infectivity of turkey hemorrhagic enteritis (he) virus was studied in poults with no detectable maternal antibody and in turkeys bursectomized or injected with killed-virus preparations. poults less than three weeks old were not infected by hemorrhagic enteritis virus, and survivors were susceptible to challenge at the age of eight weeks. three- and four-week-old poults were susceptible to he, and survivors resisted challenge. bursectomy partially interfered with the immune response but did ... | 1978 | 98158 |
| genital inoculation of male macaca fascicularis with neisseria gonorrhoeae and ureaplasma urealyticum. | inoculation of the urethra, conjunctiva, pharynx, and anal canal of six male crab-eating macaques (macaca fascicularis) with urethral exudate from male patients with urethral gonorrhoea or with laboratory gonococcal strains was unsuccessful in establishing infection or producing increased polymorphonuclear leucocytes on gram stain. intraurethral inoculation with laboratory strains of ureaplasma urealyticum resulted in transiently positive urethral cultures for u. urealyticum and was associated i ... | 1978 | 98203 |
| microbial degradation of [c14c]polystyrene and 1,3-diphenylbutane. | microbial degradation of [beta-14c]polystyrene and 1,3-diphenylbutane, a compound structurally representing the smallest repeating unit of styrene (dimer), was investigated in soil and liquid enrichment cultures. degradation rates in soil, as determined by 14co2 evolution from applied [14c]polystyrene, varied from 1.5 to 3.0% for a 4-month period. although relatively low, these percentages were 15 to 30 times greater than values previously reported. enrichment cultures, containing 1,3-diphenylbu ... | 1978 | 98222 |
| relation of nucleosomes to dna sequences. | | 1978 | 98278 |
| immunochemical studies on the 5-methylcytosine content of african green monkey satellite dna. | | 1978 | 98282 |
| nature of immune complexes formed in rhesus monkeys immunized with pr-beta-hcg-tt on challenge with hcg. | | 1978 | 98290 |
| ultrastructural hepatic changes by carbamate pesticide (sevin) in rats. | | 1978 | 98323 |
| recruitment order, contractile characteristics, and firing patterns of motor units in the temporalis muscle of monkeys. | | 1978 | 98343 |
| fatty liver in experimental protein-energy malnutrition in the rat. | | 1978 | 98345 |
| sensitivity of gonococcus strains isolated in rotterdam to epicillin, ampicillin, penicillin and tetracycline. | quantitative determinations of the sensitivity to epicillin, ampicillin, penicillin and tetracycline were carried out for 67 gonococcus strains isolated from 67 males with urogenital gonorrhoea, and 38 strains isolated from 38 females with urogenital/rectal gonorrhoea. the results of the sensitivity determinations for ampicillin, penicillin and tetracycline were compared with the findings of a previous investigation. it was found that the gonococcus strains isolated from males had become slightl ... | 1978 | 98362 |
| calcium-dependent binding of mouse epididymal spermatozoa to the zona pellucida. | | 1978 | 98372 |
| a study on the relationship dose-effect in case of gamma-irradiation on leptospira. | | 1977 | 98416 |
| altered mrna metabolism in ribonuclease iii-deficient strains of escherichia coli. | the metabolism of mrna from the lactose (lac) operon of escherichia coli has been studied in ribonuclease (rnase) iii-deficient strains (rnc-105). the induction lag for beta-galactosidase from the first gene was twice as long, and enzyme synthesis was reduced 10-fold in one such mutant compared with its isogenic rnc+ sister; in the original mutant strain ab301-105, synthesis of beta-galactosidase was not even detectable, although transduction analysis revealed the presence of a normal lac operon ... | 1978 | 98520 |
| identification of low chlorinated biphenyls in human milk by gas chromatography--mass spectrometry. | trichlorobiphenyl and tetrachlorobiphenyls in human milk were analysed by gas chromatography--mass spectrometry and mass fragmentography using silicone ov-1 and apiezon l grease as stationary phases. low-chlorinated biphenyls had been considered to be excreted rapidly from the body, but in this work quantities of tri- and tetrachlorobiphenyls amounting to approximately 30% of the total of polychlorinated biphenyls (pcbs) accumulated in the milk were identified. this result is important in relati ... | 1978 | 98535 |
| rats defend different body weights depending on palatability and accessibility of their food. | normal adult rats lived on powdered diets adulterated to contain as much as 1.6% quinine sulfate, on a palatable high-fat diet, or in skinner boxes with 45-mg noyes pellets available on fixed-ratio (fr) schedules as high as fr 156. they maintained lower body weights over periods of months in proportion to the percentage of quinine adulteration or the fixed ratio. rats exposed to the high-fat diet overate as much and gained weight as rapidly as rats recovering from food deprivation, and became mo ... | 1978 | 98538 |
| immunization with dextransucrases, levansucrases, and glycosidic hydrolases from oral streptococci. ii. immunization with glucosyltransferases, fructosyltransferases, and glycosidic hydrolases from oral streptococci in monkeys. | the feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. forty rhesus monkeys, macaca mulatta, were used. cariogenic streptococci, s mutans, were implanted into all the monkeys' mouths. there was no pathological effect resulting from immunization. of the 40 animals, 30 retained the implanted flora throughout the experiment; the remaining 10 were reimplanted until the streptococci remained. in six months, gross carious lesio ... | 1977 | 98540 |
| circadian variations in cortisol concentrations in the plasma of female rhesus monkeys. | | 1978 | 98605 |
| purification and some properties of ovine placental lactogen. | a method has been described for the purification of ovine placental lactogen (opl) involving the use of freshly obtained sheep foetal cotyledons. tissue was extracted with 0.1 m-ammonium bicarbonate and the supernatant fraction, adjusted to ph 7, was brought to 60% saturation with ammonium sulphate. the resulting precipitate was then subjected to a sequence of chromatographic steps using columns of sephadex g-100 and carboxymethylecellulose. during each stage of the purification, the lactogenic ... | 1978 | 98606 |
| observations on acute gastric dilatation in nonhuman primates. | in the years 1967-1977 we diagnosed 23 cases of acute gastric dilatation in monkeys. fourteen of these animals were macaca mulatta, five macaca fascicularis, and one each of macaca nemestrina, aotus trivirgatus, saimiri sciureus, and colobus guereza. fourteen of the animals were males, nine were females, and all were adults or subadults. mortality was 78% (18 of 23 animals). thirteen of the animals had received on anesthetic, immobilizing, or tranquilizing drug 1-2 days before developing acute g ... | 1978 | 98666 |
| effect of starvation on hypothalamic-pituitary-thyroid function in the rat. | total starvation in the rat for 2 days did not alter the hypothalamic content of thyrotropin-releasing hormone (trh), but did decrease both pituitary tsh content and serum tsh concentration. five days starvation resulted in a significant decrease in serum tsh and a slightly enhanced serum tsh response to exogenous trh, suggesting that the pituitary retains its sensitivity to trh. fasting for 5 days resulted in a decreased 1 and 4th, but an increased 24th thyroid 131i uptake. other starvation-ind ... | 1978 | 98684 |
| evidence that f' lac replicates asynchronously during the cell cycle of escherichia coli b/r. | the replication of f' lac was studied in exponentially growing cultures of e. coli b/r. the cells were pulse induced for the synthesis of beta-galactosidase and their dna pulse labelled with 3h thymidine. the cells were then separated into age classes by centrifugation through a sucrose gradient in a zonal rotor. plasmide replication was measured in each age fraction by three methods: the rate at which beta-galactosidase could be induced, the amount of label incorporated into ccc plasmid dna whi ... | 1978 | 98704 |
| suppression of oestrogen-induced lh surges by social subordination in talapoin monkeys. | | 1978 | 98718 |
| the effects of sodium nitroprusside and trimethaphan camsylate on cerebral blood flow in rhesus monkeys. | hemispheric cerebral blood flow was measured in the rhesus monkey before and after infusion of the hypotensive agents sodium nitroprusside and trimethaphan camsylate. the intracarotid injections of 133xe was utilized, and flow was calculated by the "flow initial" technique. cerebral blood flow did not change significantly with the administration of trimethaphan camsylate. however, with a small reduction in blood pressure (10.6%) during the administration of sodium nitroprusside, the cerebral blo ... | 1978 | 98729 |
| electron-microscopic identification of axonal initial segments belonging to interneurons in the dorsal lateral geniculate nucleus of the monkey. | | 1978 | 98733 |
| the bacterial pathogenesis of acute pelvic inflammatory disease. | to study the bacterial pathogenesis of acute pelvic inflammatory disease, peritoneal fluid was obtained by culdocentesis in 133 of 344 women with this disease. in 104 of the specimens bacteria were identified both in the gram-stained smear and culture. neisseria gonorrhoeae was isolated from the lower genital tract in over half of these women, and there were 3 patterns of bacterial recovery from peritoneal fluid: n gonorrhoeae alone (22%), n gonorrhoeae and other organisms (32%), and nongonococc ... | 1978 | 98745 |
| reduced hepatic bilirubin uridine diphosphate glucuronyl transferase and uridine diphosphate glucose dehydrogenase activity in the human fetus. | hepatic bilirubin uridine diphosphate glucuronyl transferase (udpg-t) activity was 0.14 and 0.22 units in two fetuses aged 17 and 22 weeks, respectively, and less than 0.1 unit in 15 fetuses, aged 8--19 weeks compared to 0.68--1.99 units in 21 normal adults. hepatic uridine diphosphate glucose dehydrogenase (udpg-d) activity in 14 fetuses, aged 8--18 weeks, ranged from 6.2--15.0 units (mean = 11.3 +/- 0.7) compared to 28.8--49.2 units (mean = 39.6 +/- 2.5) in eight normal adults (p less than 0.0 ... | 1978 | 98749 |
| location of the genes for human heavy chain immunoglobulin to chromosome 6. | immunoglobulin synthesis was examined in 31 man-mouse hybrid clones produced by fusing rag mouse cells with human lymphoid cells. cells were grown in serum-free medium containing [(14)c]leucine and a (14)c-labeled amino acid mixture. spent medium was dialyzed, concentrated, and subjected to radioimmunoelectrophoresis. eighteen clones were found to produce material that gave a radiolabeled precipitin line with anti-human igg (gamma-chain specific). production of material which was indistinguishab ... | 1978 | 98768 |
| contraction of detergent-treated smooth muscle. | after exposure of segments of rabbit taenia coli to the nonionic detergent triton x-100, tension could be induced by increasing the [ca2+] in the micromolar range. in the presence of a saturating [ca2+], this preparation developed nearly 100% of the control tetanus tension recorded from the intact muscle prior to the detergent treatment. in addition, tension could be induced by increasing the [mg2+], in the virtual absence of ca2+. mg2+ seems to inhibit the ca2+-induced tension in a predominantl ... | 1978 | 98770 |
| plasma membrane vesiculation: a cellular response to injury. | the shedding of plasma membrane vesicles has been shown to result from exposure of monolayer cell cultures to formaldehyde and other sulfhydryl blocking agents. incubation of cells in concentrations of these agents as low as 5 to 10 mm for intervals as brief as fifteen minutes is effective (scott, 1976). plasma membrane vesiculation has been shown to be an energy-dependent process that requires ca++ and physiological temperature. following plasma membrane vesiculation, cell monolayers appear int ... | 1978 | 98904 |
| quantitation of particles in the freeze-fractured nuclear membrane after renal ischemia. | changes in the number and sizes of membrane-associated particles have been quantitated in the protoplasmic (p) and exoplasmic (e) fracture faces of the outer membrane of nuclei isolated from the inner cortex following renal ischemia and reflow in the rat. no changes were observed in the inner nuclear membrane. after 20-min ischemia, the number of particles in both fracture faces decreased. with reflow, the total number of particles decreased after both 20- and 60-min ischemia. the partition coef ... | 1978 | 98907 |
| [some aspects relating to the aflatoxin generation during the self-heating of cereals]. | in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ... | 1978 | 98933 |
| age-associated changes in the blood picture of the goat. | | 1978 | 98936 |
| the effect of complement depletion on bacterial lipopolysaccharide (lps)-induced hemodynamic and hematologic changes in the rhesus monkey. | lipopolysaccharide (lps) isolated from salmonella minnesota r595 or from escherichia coli 0111:b4 induces hypotension in rhesus monkeys with normal complement levels. this hypotension is accompanied by decreased total peripheral resistance. the depletion of c3 and terminal complement components by prior intraperitoneal administration of the anticomplementary protein cobra factor did not alter the hemodynamic changes which occur following the rapid injection of 5 mg/kg of r595 lps, the infusion o ... | 1978 | 99042 |
| catabolism and protein binding of tc-99m pyridoxylideneglutamate. | various tc-99m-labeled compounds have been suggested as replacements for [i-131] rose bengal for imaging of the hepatobiliary system. among such compounds are schiff's bases, which are tin-free tc-chelates easily prepared by 30-min autoclaving of an equimolar mixture of pyridoxal and an amino acid at ph 8.5. we have compared the properties of several schiff's bases, including tc-99m pyridoxylideneglutamate (tc pyg) with [i-131] rose bengal. under conditions described, tc-pyg can be prepared free ... | 1978 | 99499 |
| nature's infant nutrition. breast feeding: a means of imparting immunity? | | 1978 | 99622 |
| the effects of foveal prestriate and inferotemporal lesions on matching to sample behaviour in monkeys. | | 1978 | 99683 |
| behavioral measurement measurements of excitability changes in reward sites in the dog: a frequency dependent effect. | | 1978 | 99757 |
| morphology of freeze-etched treponema refringens (nichols). | the freeze-etch technique was used to study the morphology of treponema refringens (nichols). there is a single band of cytoplasmic fibrils which follows a path in the form of a right-handed helix with a periodicity of 1500 nm around the body of the treponeme just below the cytoplasmic membrane. there are two major fracture planes, one located in the interior of the outer envelope and the second in the interior of the cytoplasmic membrane. the "blebs" or "surface protuberances", which are quite ... | 1978 | 100069 |
| ultraviolet light-induction and photoreactivation of thymine dimers in a cyanobacterium, anacystis nidulans. | partially photoreactivable mutant of anacystis nidulans demonstrates partial photorepair of thymine dimers. the wild type which is completely photoreactivable at the conditions studied shows higher level of thymine dimer photolysis. | 1978 | 100072 |
| [delayed implantation and early developmental defects in the mouse caused by pcb: 2,2'-dichlorobiphenyl (author's transl)]. | pregnant mice administered per os during the days 1--3 (plug day = day 0) post conception (p.c.) with 375 mg 2,2'-dichlorobiphenyl/kilograms/day revealed on day 18 p.c. increased number of resorptions and doses up from 500 milligrams/kilograms/day led to a substantial retardation of the prenatal development. based on the investigations during the early development it is concluded, that retardation of the fetus is caused by a delayed implantation. it is assumed, that increased resorption is due t ... | 1978 | 100080 |
| trifluridine in resistant human herpetic keratitis. | patients with active dendritic herpetic keratitis that was unresponsive to topical idoxuridine or vidarabine therapy were treated topically with a 1% solution of trifluridine. the dendritic ulcers healed in an average time of 6.1 days. all patients tolerated the drug well except for one patient in whom a reversible crystalline epithelial keratitis developed. | 1978 | 100084 |
| cooperative binding of mn2+ and non-cooperative binding of mg2+ to beta-galactosidase (e. coli). | | 1978 | 100107 |
| [picosecond energy transfer between the spectral forms of pigments from the reaction center of rhodospirillum rubrum]. | absorption changes of reaction centers from rhodospirillum rubrum at 748, 796 and 870 nm induced by 532 and 870 nm picosecond light pulses were investigated with a picosecond spectrometer. kinetics of absorption changes at 748 and 796 had an additional bleaching when induced by the 532 nm pulse, in comparison with those at 870 nm. the additional bleaching was interpreted as a result of the excitation energy transfer via spectral forms of pigments of reaction centers. the experimental results fit ... | 1978 | 100143 |
| [origin of a mitogrenic factor for cultivated macrophages (imf: inflammatory mitogenic factor) found in exudates of non-specific acute inflammation]. | the mitogenic activity of inflammatory exudate obtained from irradiated rats is reduced. after transfer of bone marrow syngeneic cells into irradiated rats this mitogenic activity is further decreased, while after transfer of thymic cells it is increased. it is postulated that the mitogenic activity of inflammatory exudate could be related to thymic cells and that t lymphocytes may be involved in non specific-inflammatory reactions. | 1978 | 100246 |
| clinical and pathologic features of various drug-related problems in the control of swine dysentery. | | 1978 | 101498 |
| detergent-resistant variants of bacillus subtilis with reduced cell diameter. | variants of bacillus subtilis resistant to the detergent triton x-100 may exhibit: (i) normal cell morphology, (ii) reduced cell diameter, or (iii) helical cell shape. one variant of type ii was studied in some detail. triton resistance, cell diameter reduction, and poor sporulation all may have resulted from a single mutation. high concentrations of triton caused rapid lysis of wild-type cells. b. subtilis adapted to low triton concentrations such that, upon subsequent exposure to higher concen ... | 1978 | 101507 |
| occurrence of squalene and sterols in cellulomonas dehydrogenans (arnaudi 1942) comb. nov. hester 1971. | the neutral lipid fraction of the photochromogenic, coryneform bacterium cellulomonas dehydrogenans (arnaudi 1942) comb. nov. contains the sterol precursor squalene and at least two sterols, cholesterol and beta-sitosterol. the compounds were characterized by mass spectrometry and combination gas-liquid chromatography--mass spectrometry. de novo sterol biosynthetic ability was shown from incorporation of 14c from d-[u-14c]glucose into squalene and the sterol fraction. the squalene concentration ... | 1978 | 101527 |
| detection of intermediates in protein folding of carbonic anhydrase with fluorescence emission and polarization. | the three-dimensional structure of carbonic anhydrase is a result of specific folding of the protein chain to form a compact, globular molecule. fluorescence measurements on the nature of the rate-limiting steps in folding from the random coil to the native structure show that each step involves an actual folding reaction of the protein chain. emission intensity and polarization of the intrinsic fluorescence due to tryptophan residues reach a maximum during the early period of the folding proces ... | 1978 | 101537 |
| studies of the lymphoreticular system in the pathogenesis of scrapie: the role of spleen and thymus. | | 1978 | 101558 |
| incorporation of amino acids by isolated submitochondrial fractions of lactating goat mammary gland in vitro. | incorporation of amino acids by mitochondria and its subfractions from mammary gland of the goat during lactation was studied in vitro. assessment of distribution of radioactivity incorporated by intact mitochondria into its subfractions revealed maximum specific activity in the inner membrane. during lactation the inner membrane of mitochondria exhibited further stimulation in such incorporation. matrix was the next active fraction whereas outer membrane and peripheral space had negligible radi ... | 1978 | 101564 |
| serologic typing of rickettsiae of the spotted fever group by microimmunofluorescence. | | 1978 | 101593 |
| [salmonellosis]. | | 1978 | 101617 |
| [exocrine gland activities and the kinin system]. | | 1978 | 101694 |
| studies on virus-inhibiting substances of bacterial origin. iv. antiviral substances extractable from streptococcus faecalis: its in vivo effect. | | 1978 | 101714 |
| the effect of dinitrochlorobenzene (dncb) on dimethylbenzathracene (dmba) carcinogenesis on hamster buccal pouch. | dncb is an antigen that stimulates the cell-mediated response in a sensitized host. the purpose of this study was to define the effect dncb would have on a standard model system for oral carcinogenesis, theorizing that tumorgenesis would be delayed or inhibited. fifty-six syrian hamsters were divided into four groups. in group a (dncb/dmba), the right buccal pouch of twenty animals was treated with 2% dncb in orabase, twice a week, and 0.5% dmba, three times a week, for 10 weeks. in group b, twe ... | 1978 | 101932 |
| [microbiological characteristics of intestinal dysbacteriosis in acute leukemia]. | | 1978 | 101983 |
| oxygen requirement for prostaglandin biosynthesis. | the formation of prostaglandins by vesicular gland cyclooxygenase can be regulated by o2 concentrations below 30 micron (20 mm hg) with an apparent km value of about 5 micron. this result suggests that most mammalian tissues might be expected normally to have sufficient o2 for some synthesis, and that only occasionally, would the level of oxygen available within some tissues become marginally inadequate to sustain a high rate of prostaglandin biosynthesis. | 1978 | 102002 |
| effect of arachidonic acid on some inhibitors of the human platelet release reaction. | | 1978 | 103548 |
| immunological heterogeneity of haemophilia b: a multicentre study of 98 kindreds. | an electroimmunoassay with a precipitating rabbit anti-human factor ix antiserum and an inhibitor neutralization assay with a non-precipitating homologous antibody were used to measure factor ix antigen (ix:ag) in 117 patients from 98 kindreds with haemophilia b; and to investigate in a mixed population the incidence of different immunological types of the disease. although the two assays showed an excellent correlation, the electroimmunoassay was selected for its simplicity as a criterion for c ... | 1978 | 103564 |
| effect of cobalt-60 radiation on response to endodontic therapy in monkeys. | response of teeth that had received therapeutic doses of cobalt-60 radiation to endodontic therapy were investigated in three monkeys. the results indicated no appreciable effect of the irradiation on the response to root canal treatment aside from reduction in osteoblastic activity. | 1978 | 103612 |
| [epileptogenic action of intra-amygdaloid injection of kainic acid]. | intra-amygdaloid unilateral application of low doses of kainic acid rapidly elicits, in both chronic and acute conditions, secondarily generalized convulsive seizures which often culminate in fatal true status epilepticus unless appropriate anti-epileptic drugs are provided. spontaneous recurrent seizures are observed for several hours starting approximately 10 min. after the application of kainic acid. in addition to the primary degeneration in the amygdaloid complex, a secondary cell loss is s ... | 1978 | 103652 |
| focal penicillin epilepsy in an isolated cerebral hemisphere. | | 1978 | 103744 |
| toxoplasma gondii: penetration into differentiating friend erythroleukemia cells. | | 1978 | 103745 |
| a receptor for polymerized human and chimpanzee albumins on hepatitis b virus particles co-occurring with hbeag. | a receptor for polymerized human serum albumin was demonstrated on dane particles as well as on 20-nm hepatitis b surface antigen particles, isolated from asymptomatic carriers of hepatitis b virus who were positive for hbeag. in contrast, such receptor was not born by 20-nm hepatitis b surface antigen particles obtained from carriers positive for antibody to hbeag. hepatitis b surface antigen particles with the receptor were heavier than those without, and when treated with pronase, they became ... | 1979 | 103774 |
| shigellosis and escherichia coli diarrhea: relative importance of invasive and toxigenic mechanisms. | shigellae and dysentery-like escherichia coli must invade the epithelium of the colon to cause disease which can present as dysentery, diarrhea, or both. this paper addresses the possible role of a shigella dysenteriae-like (shiga-like) toxin in the pathogenesis of shigellosis and e. coli diarrheal diseases. the possibility for such a role is suggested by the following observations: 1) diarrhea, considered to be a result of secretion of water by the small bowel, is frequently observed in shigell ... | 1979 | 104615 |
| quantitative determination of trinitroglycerin in human plasma. | we developed a simplified method for quantitative measurement of trinitroglycerin in human plasma using hexane extraction and analysis by gas-liquid chromatography with electron-capture detection. this assay was linear from 0.5-60 ng/ml. sensitivity and reproducibility were +/- 0.5 ng/ml. we used this assay to evaluate the pharmacodynamics of trinitroglycerin in 14 patients. maximum plasma levels were similar with trinitroglycerin given by constant intravenous infusion (1.6 +/- 0.4 ng/ml (sem)), ... | 1979 | 104804 |
| high affinity uptake sites for taurine in the retina. | | 1978 | 104877 |
| demonstration of a rabbit cell surface ig that bears light chain and vh9, but lacks mu-, alpha-, and gamma-allotypes-rabbit igd? | | 1979 | 105044 |
| implications for adult roles from differential styles of mother-infant bonding: an ethological study. | ethological observations of maternal and infant behaviors of nine vervet monkey pairs (cercopithecus aethiops sabaeus) showed the effects of differential styles of early maternal responsiveness on later infant competence. those infants receiving the least amount of maternal responsiveness and the most time-off the mother in the first 3 months of development were more socially competent at 6 months of age. the results are discussed within current ethological "attachment" theories. the detachment ... | 1979 | 105083 |
| leukemia in workers exposed to ethylene oxide. | ethylene oxide, a gaseous sterilant extensively used within health care facilities, is known to be a mutagen in bacteria and in human lymphocytes. the environmental protection agency as well as the national institue of occupational safety and health have recently stipulated certain conditions for the use of ethylene oxide despite the lack of case reports or epidemiologic studies concerning carcinogenicity. we report three cases of leukemia that occurred between 1972 and 1977 in a relatively smal ... | 1979 | 105157 |
| construction of a recombinant plasmid composed of b. subtilis leucine genes and a b. subtilis (natto) plasmid: its use as cloning vehicle in b. subtilis 168. | | 1978 | 105237 |
| production of antivenom against detoxified taipoxin and immunochemical analysis of the alpha, beta and gamma subunits. | | 1979 | 105431 |
| [some notes on the specifity of the fluorescence histochemical demonstration of gaba (author's transl)]. | the distribution of the gaba in the purkinje cells of the rat cerebellum was demonstrated by means of modified fluorescence histochemical method according to wolman (1971). three types of purkinje cells, with respect to their fluorescence intensity and gaba distribution, were evident. the gaba-fluorescence was strikingly by pharmacological pretreatment. isonicotinic acid hydrazide, penicillamine and chlorpromazine cause a granulation and marked reduction of the fluorescence compound, being norma ... | 1978 | 105559 |
| case report: intestinal clearance of calcium and protein in waldenstrom's macroglobulinemia. | a 63-year-old man with waldenstrom's macroglobulinemia had severe steatorrhea, marked protein-losing enteropathy, and excessive endogenous fecal calcium clearance. the malabsorption and protein loss resulted in weight loss and hypoalbuminemia. in contrast, the striking enteric calcium loss was completely compensated by an increase in calcium absorption resulting in a positive calcium balance. | 1978 | 105640 |
| on the sites of the negative and positive feedback actions of estradiol in the control of gonadotropin secretion in the rhesus monkey. | ovariectomized rhesus monkeys bearing hypothalamic lesions which had abolished endogenous lhrh production, as evidenced by a profound reduction in gonadotropin secretion, but in which lh and fsh secretion was reestablished by a chronic intermittent iv infusion of synthetic lhrh (1 microgram/min for 6 min every hour) were used to investigate the sites of the negative and positive feedback actions of estradiol in the control of gonadotropin secretion. the administration of estradiol to such animal ... | 1978 | 105873 |
| thyrotropin response to thyrotropin-releasing hormone in the euthyroid rat: dose-response, time course, and demonstration of partial refractoriness to a second dose of thyrotropin-releasing hormone. | | 1978 | 105883 |
| food toxins and their implication in human health. | | 1978 | 105997 |
| [lithium and pregnancy (author's transl)]. | the problem has been considered of the action of lithium salts on the progress of pregnancy and on the product of the conception. lithium can bring about serious troubles in morphogenesis in invertebrate animals. the results obtained in mammals in laboratory experiments differ from species to species but it seems that these animals can be given about 8 to 9 times the levels of lithium that are used in man without causing teratogenic effects. a statistical review of the children born to human mot ... | 1978 | 106083 |
| the metabolism and disposition of 3,4,4'-trichlorocarbanilide in the intact and bile duct-cannulated adult and in the newborn rhesus monkey (m. mulatta). | | 1978 | 106490 |
| [calcium kinetics of myocardium in experimental hypercalcemia and isoproterenol lesions--ultrastructural and roentgen microanalytical findings]. | | 1978 | 106573 |
| [antibody induced phase variation in pseudomonas aeruginosa (author's transl)]. | to extend the flagella specific h antigenic schema of p. aeruginosa (ansorg, 1978), investigations are carried out to reveal phase variation in this species as in salmonella or arizona. with conventional methods, i.e. examination of single colonies after plating the cultures on standard nutrient agar or the phase reversal techniques of craigie (1931) and gard (1938) by adding homologous anti-oh-serum of different amounts in semisolid agar medium, no change of the flagellar antigens of various p. ... | 1978 | 106580 |
| [multiple molecular forms of erythrocyte carbonic anhydrase of sheep (author's transl)]. | three major forms ci, cii and cx and the minor component ci1v of ovine erythrocyte carbonic anhydrase have been identified in the ethanol chloroform extract of the hemolysate by electrophoresis on cellulose acetate and isoelectrofocusing. isolation of the four forms was achieved by chromatography on deae-sephadex a-50. comparative studies suggest that: (1) form ci1v is a modified form of ci, (2) form cx is ci plus glutathione and (3) forms ci and cii are isoenzymes which differ in their primary ... | 1979 | 106895 |
| baroreceptor control of atrioventricular conduction in man. | although human baroreflexes are known to exert a powerful physiological control on heart rate, little information exists on the physiological control they exert on the atrioventricular conduction system. in 11 normotensive subjects with normal atrioventricular conduction, we altered baroreceptor activity by injection of pressor and depressor drugs (phenylephrine and trinitroglycerin) and recorded mean arterial pressure (map, catheter measurements), r-r interval, and pre-his and post-his interval ... | 1979 | 106985 |
| liver transplantation. | | 1979 | 107000 |
| effect of pregnancy and lactation on glycosyltransferase activities of rat mammary gland. | | 1979 | 107054 |
| rapid demineralization in acidic buffers. | the demineralization of routine histological specimens in buffers of weakly ionized organic acids, unbuffered formic acid, and edta was investigated. the rate of demineralization was measured by a chemical method and from radiographs. lactate-containing buffers and buffers of formic acid with its potassium salt were more rapid in effect than any other agent. acidic buffers and unbuffered formic acid produced rapid diffuse demineralization with secondary precipitation of calcium salts. preservati ... | 1979 | 107151 |
| regulation of teichoic acid synthesis during phosphate limitation. | bacillus subtilis w-23, when placed in phosphate-free medium, ceases to synthesize teichoic acid and synthesizes teichuronic acid. the enzymatic basis for the cessation of teichoic acid synthesis is the irreversible inhibition of the first membrane-bound enzyme involved in teichoic acid synthesis which catalyzes the reaction undecapenol-p + udp-glcnac leads to undecaprenol-p-p-glcnac + ump. | 1979 | 107156 |
| alcohol, malnutrition and liver disease. | | 1979 | 107268 |
| dietary protein, aryl hydrocarbon hydroxylase and chemical carcinogenesis in rats. | | 1979 | 107295 |
| effects of dietary composition on somatomedin activity in growing rats. | | 1979 | 107298 |
| tumor-host responses to various nutritional feeding procedures in rats. | parenteral and enteral nutrition are being used as adjuncts to cancer therapy. a liquid diet formulation containing a 27% solution of glucose and 3.9% crystalline amino acids with electrolytes and vitamins was given continuously for a week via parenteral (iv), and via intragastric (ig) routes and also was given ad libitum via the oral or per os (po) route to groups of buffalo rats with and without a morris no. 7777 transplantable hepatoma to find out how these feeding procedures affect tumor-hos ... | 1979 | 107299 |
| rna polymerase binding sites and transcription map of the dna of bacillus subtilis phage phi29. | | 1979 | 107317 |
| retinal pigment epithelium. interrelations of endoplasmic reticulum and melanolysosomes in the black mouse and its beige mutant. | by cytochemistry (acid phosphatase and tyrosinase activities) gerl, a specialized hydrolase-rich region of endoplasmic reticulum (er), can be visualized in the cells of the mouse retinal pigment epithelium. previously catalase cytochemistry permitted us to identify microperoxisomes, with numerous continuities to the er. the present report reveals the extensive continuities of the er to pigment granules in various stages of maturation. when the pigment granules, which we consider to be "melanolys ... | 1979 | 107366 |