| maternal, infant, and delivery factors associated with neonatal thyroid hormone status. | thyroid function is dynamic during the perinatal period with many factors potentially influencing maternal, fetal and neonatal tsh and thyroid hormone levels. we sought to identify the impact of numerous maternal, fetal and delivery attributes on thyroid parameters in newborns. | 2008 | 18302520 |
| migratory azygos vein: a case report. | we report a case of a "migrating" azygos vein developing after an abrupt spinal deformity adjacent to the azygos arch. a woman with a previously identified azygos lobe had a follow-up chest computed tomography that demonstrated the azygos vein dislocated medially to the fissure in its usual mediastinal position. the azygos lobe was intact. the woman had developed kyphosis angled at the level of the t4 vertebra, where the azygos vein arches anteriorly. | 2008 | 18303296 |
| cisplatin-based three drugs combination (nip) as induction and adjuvant treatment in locally advanced non-small cell lung cancer: final results. | this phase iii trial was conducted in non-small cell lung cancer patients with locally advanced stage ii b (only t3n0) iii a and iii b (only t4 n0). primary endpoint was 2-year survival; secondary were toxicity, disease-free survival, and overall survival. | 2008 | 18303436 |
| [identification and phylogenetic analysis of one strain of lactobacillus delbrueckii subsp. bulgaricus separated from yoghourt]. | for being further applied and studied, one strain of lactobacillus delbrueckii subsp. bulgaricus (wch9901) separated from yoghourt which had been identified by phenotype characteristic analysis was identified by 16s rdna and phylogenetic analyzed. | 2007 | 18303633 |
| breast cancer in tunisia in 2004: a comparative clinical and epidemiological study. | the aim of this study was to determine the epidemiological, clinical and anatomopathological aspects of breast cancer in tunisia. we censored and analyzed all cases of breast cancer newly diagnosed in tunisia during the year 2004. during that year, 1437 new cases of invasive breast cancer were diagnosed and 35 cases of non invasive breast cancer. there were 1408 women and 29 men. the accrual incidence was 27.1 and the standardized incidence was 28.5. the mean age for women was 51 years. the mean ... | 2008 | 18304901 |
| treatment and prevention of recurrence of multinodular goiter: an evidence-based review of the literature. | reportedly, 10-15% of patients with goiters ultimately require operative intervention, and recurrences of multinodular goiter (mng) account for up to 12% of all thyroid operations. | 2008 | 18305998 |
| recovery of neuromuscular blockade caused by vecuronium is delayed in patients with hypertriglyceridemia. | we investigated the effects of hypertriglyceridemia on the onset and recovery of neuromuscular blockade, induced by vecuronium, over the adductor pollicis muscle, electromyographically. eighteen adult patients with hypertriglyceridemia (hypertriglyceridemia group) and 18 healthy patients with normal serum triglyceride (control group) were studied. the supramaximal stimulating current for train-of-four (tof) in the hypertriglyceridemia group was significantly higher than that in the control group ... | 2008 | 18306024 |
| minimally invasive anterior approach for kyphoplasty of the first thoracic vertebra in a patient with multiple myeloma. | a vertebral body collapse of the first thoracic vertebra (t1) was diagnosed after radiological investigation in an adult male suffering for severe dorsal pain due to suspected multiple myeloma (mm). according to the principles of minimally invasive neurosurgery and the aesthetic needs of the patient, an open t1 kyphoplasty was performed by means of a right anterior approach through the inferior brow of the neck, generally utilized for the anterior approaches to the cervical spine. the histologic ... | 2008 | 18306128 |
| the interaction of cyp3a5 polymorphisms along the androgen metabolism pathway in prostate cancer. | prostate cancer is a leading solid tumor among men in the western world. androgens play an important role in the carcinogenesis and treatment of prostate cancer. cyp3a5 is a cytochrome p450 superfamily member which also has activity in testosterone metabolism. in this study, we looked for two-gene interactions associated with clinical characteristics of prostate cancer in the finnish population. we used multifactor-dimensionality reduction for the identification of the two-gene interactions in a ... | 2008 | 18306354 |
| giant t4 rectal carcinoma mimicking urinary bladder adenocarcinoma accurately diagnosed by immunohistochemistry and successfully treated with total pelvic exenteration: report of a case. | a 54-year-old man, with the chief complaints of hematuria, pollakisuria, and pneumaturia, was referred to our hospital, with a diagnosis of giant urinary bladder adenocarcinoma with massive invasion to the rectum. on the basis of the radiological diagnosis and findings of hematoxylin and eosin (h&e) of biopsy specimens, it was difficult to conclude whether the adenocarcinoma originated in the bladder or in the rectum. the immunohistochemical staining of the biopsy specimens showed cytokeratin 7 ... | 2008 | 18307003 |
| pharmacokinetics of total thyroxine in dogs after administration of an oral solution of levothyroxine sodium. | oral l-thyroxine (l-t4) supplementation is used to replace thyroid hormone concentrations in dogs with hypothyroidism. the pharmacokinetics of l-t4 following administration of a solution (leventa) was investigated in healthy dogs. l-t4 was absorbed fairly rapidly (t(max) 3 h). a mean bioavailability of 22% was calculated following a single oral administration of 40 microg l-t4/kg body weight. repeated oral administration at the same dose for 14 consecutive days did not lead to any accumulation o ... | 2008 | 18307500 |
| atrial fibrillation associated with a thyroid stimulating hormone-secreting adenoma of the pituitary gland leading to a presentation of acute cardiac decompensation: a case report. | hyperthyroidism is a well established cause of atrial fibrillation (af). thyroid stimulating hormone-secreting pituitary tumours are rare causes of pituitary hyperthyroidism. whilst pituitary causes of hyperthyroidism are much less common than primary thyroid pathology, establishing a clear aetiology is critical in minimising complications and providing appropriate treatment. measuring thyroid stimulating hormone (tsh) alone to screen for hyperthyroidism may be insufficient to appropriately eval ... | 2008 | 18307779 |
| selective arterial prostatic embolization (sape) for refractory hematuria of prostatic origin. | to assess sape as an alternative treatment option in patients with refractory hematuria of prostatic origin. | 2008 | 18308078 |
| novel azaphilones, kasanosins a and b, which are specific inhibitors of eukaryotic dna polymerases beta and lambda from talaromyces sp. | kasanosins a (1) and b (2) are novel azaphilones isolated from cultures of talaromyces sp. derived from seaweed, and their structures were determined by spectroscopic analyses. these compounds selectively inhibited the activities of eukaryotic dna polymerases beta and lambda (pols beta and lambda) in family x of pols, and compound 1 was a stronger inhibitor than compound 2. the ic(50) values of compound 1 on rat pol beta and human pol lambda were 27.3 and 35.0 microm, respectively. on the other ... | 2008 | 18308572 |
| long-term outcome following radical temporal bone resection for lateral skull base malignancies: a neurosurgical perspective. | primary temporal bone malignancy is a rare form of tumor for which the therapeutic strategy remains controversial. in this study, the authors reviewed their experience with radical temporal bone resection (tbr) of such lesions and analyzed the long-term results to provide treatment recommendations. | 2008 | 18312097 |
| gender differences in the effects of organochlorines, mercury, and lead on thyroid hormone levels in lakeside communities of quebec (canada). | environmental chemicals can disrupt endocrine balance and in particular thyroid hormone (th) homeostasis. however, studies differ with respect to thyroid profile changes and gender differences are rarely examined. this study investigated the ths, triodothyronine (t3), thyroxine (t4), and thyroid stimulating hormone (tsh), in relation to serum organochlorines (ocs), bioindicators of mercury (hg) and blood lead (pb) in 211 freshwater fish consumers (124 men and 87 women) from two communities in ca ... | 2008 | 18313043 |
| feasibility of vermicomposting in biostabilization of sludge from a distillery industry. | the feasibility of vermicomposting technology to stabilize the distillery industry sludge mixed with a bulking agent (cow dung) in different proportions viz. 20% (t1), 40% (t2), 60% (t3) and 80% (t4), was tested using composting earthworm perionyx excavatus for 90 days. the vermitreated sludge was evaluated for different physico-chemical parameters and all vermibeds expressed a significant decrease in ph (10.5-19.5%) organic c contents (12.8-27.2%), and an increase in total n (128.8-151.9%), ava ... | 2008 | 18313726 |
| origin activation requires both replicative and accessory helicases during t4 infection. | the bacteriophage t4 has served as an in vitro model for the study of dna replication for several decades, yet less is known about this process during infection. recent work has shown that viral dna synthesis is initiated from at least five origins of replication distributed across the 172 kb chromosome, but continued synthesis is dependent on recombination. two proteins are predicted to facilitate loading of the hexameric 41 helicase at the origins, the dda accessory helicase and the 59 loading ... | 2008 | 18314134 |
| do existing psychologic scales measure the nonspecific benefit associated with cam treatment? | to determine whether existing psychologic well-being scales are sensitive to change after complementary and alternative medicine (cam) treatment, and whether changes in those scales of well-being correlate with symptom change. this may limit the need for the development of new cam-specific outcomes. | 2008 | 18315505 |
| tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy. | the major pathologic markers of prognosis in colorectal cancer include vascular invasion by tumor cells, invasion of adjacent lymph nodes, and perforation of the serosal wall. recent work suggests that a high density of tumor-infiltrating lymphocytes (til) is associated with good outcome independently of these established prognostic markers. the aim of the present study was to investigate the prognostic significance of tils and other routinely reported pathologic features in colon cancer, partic ... | 2008 | 18316563 |
| validation study of the proposed iaslc staging revisions of the t4 and m non-small cell lung cancer descriptors using data from 23,583 patients in the california cancer registry. | we performed a validation study of the proposed international association for the study of lung cancer (iaslc) tumor, node, metastasis (tnm) and stage grouping revisions on advanced nonbronchioloalveolar carcinoma (non-bac) non-small cell lung cancer (nsclc). | 2008 | 18317063 |
| visuomotor expertise and dimensional complexity of cerebral cortical activity. | this study employed the correlation dimension (d2) to examine whether visuomotor expertise was inversely related to the complexity of cerebral cortical activity. | 2008 | 18317368 |
| [pelvic exenteration for t4 rectal cancer: a series of 15 ressectable cases]. | pelvic exenteration is the best therapeutic choice for treatment of t4 rectal cancer. although, this operation still presents considerable mortality and high morbidity. | 2007 | 18317645 |
| photocatalytic antimicrobial activity of thin surface films of tio(2), cuo and tio (2)/cuo dual layers on escherichia coli and bacteriophage t4. | tio(2)-coated surfaces are increasingly studied for their ability to inactivate microorganisms. the activity of glass coated with thin films of tio(2), cuo and hybrid cuo/tio(2) prepared by atmospheric chemical vapour deposition (ap-cvd) and tio(2) prepared by a sol-gel process was investigated using the inactivation of bacteriophage t4 as a model for inactivation of viruses. the chemical oxidising activity was also determined by measuring stearic acid oxidation. the results showed that the rate ... | 2008 | 18317747 |
| midline spikes. | midline spikes are characterized by spike foci recorded at cz, fz, or pz with amplitude ranging from 20 to 350 microvolts. out of 7,929 eegs performed at the neurodiagnostics laboratory, kaiser permanente medical center, anaheim, california, between 1996 and 2006, 17 eegs (0.21%) were identified as having interictal midline spikes with or without other epileptiform discharges. eight eegs showed midline spikes at cz, 2 at fz, 2 at cz and fz, 1 at cz and c3, 1 at cz, c3, and p3, 1 at cz and f8, 1 ... | 2008 | 18318416 |
| development and validation of an inductively coupled plasma mass spectrometry method for quantification of levothyroxine in dissolution studies. | a simple, sensitive and reproducible inductively coupled plasma mass spectrometry (icp-ms) method for the direct determination of levothyroxine (t4), based on the analysis of iodide content, in aqueous media was developed. the sample preparation consisted of addition of antimony, as the internal standard, and dilution with a 0.5% ammonia solution. the analytes were quantified at m/z 126.90 and 120.90 for iodide and antimony, respectively. the assay was linear in the concentration range of 0.1-50 ... | 2008 | 18320549 |
| [thoracoscopic sympathectomy for arterial ischemia of the upper extremities: a case report]. | thoracoscopic surgery reduce the morbidity of sympathectomy. major indications of video-assisted sympathectomy (vat) include hyperhidrosis, raynaud's disease, causalgia, and reflex sympathetic dystrophy. because little information is available in the national and international literature vat sympathectomy in the treatment of upper extremities ischemia, we decided to present our first case. clinic case: the 38 years old patient was hospitalized for left upper-extremity ischemia (raynaud's syndrom ... | 2007 | 18320797 |
| identification of patients with high-risk stage ii colon cancer for adjuvant therapy. | adjuvant therapy for stage ii colon cancer remains controversial but may be considered for patients with high-risk features. the purpose of this study was to assess the prognostic significance of commonly reported clinicopathologic features of stage ii colon cancer to identify high-risk patients. | 2008 | 18322753 |
| [outcome of surgical and adjuvant radiotherapy treatment of t3-t4 squamous cell carcinoma of the floor of the mouth: evaluation of oncological control and treatment related morbidity]. | the aims of this study were to evaluate the therapeutic outcome and morbidity associated with management of squamous cell carcinoma (scc) t3-t4 of the floor of the mouth. | 2007 | 18323327 |
| dry small pleural dissemination of adenocarcinoma of the lung preoperatively detected by pet/ct: a report of two cases. | dry pleural dissemination in non-small cell lung cancer, defined as solid pleural metastasis of lung cancer without pleural effusion, is a condition occurring in t4 lung cancer. positron emission tomography (pet) has been reported to be useful for the diagnosis and staging of lung cancer. it has been reported that positive findings on pet scans of indeterminate pleural abnormalities at computed tomography (ct) are sensitive to malignancy. we encountered two cases of dry small pleural disseminati ... | 2008 | 18323864 |
| papillary thyroid carcinoma: factors influencing recurrence and survival. | the prognosis of patients with papillary thyroid carcinoma (ptc) is usually favorable; however, a subset of patients can develop local recurrence or distant metastases. the aim of this study was to evaluate the prognostic factors influencing the recurrence and the survival rate in 950 ptc patients. | 2008 | 18324441 |
| thyrotoxic periodic paralysis in an italian man: clinical manifestation and genetic analysis. | in western countries, thyrotoxic periodic paralysis (tpp) is a rare condition with only sporadic cases described so far. here, we describe a 29-year-old italian man who presented with leg weakness and hypokalaemia. treatment with intravenous potassium resulted in a rapid resolution of symptoms. tpp as the underlying cause was suggested by suppressed thyroid-stimulating hormone (tsh), elevated free t3 and free t4, and the presence of tsh-receptor antibodies (trab). genetic analysis showed no muta ... | 2008 | 18325191 |
| atp-induced shrinkage of dna with mukb protein and the mukbef complex of escherichia coli. | fluorescence microscopic observation of individual t4 dna molecules revealed that the mukbef complex (bacterial condensin) and its subunit, the mukb (a member of the smc [structural maintenance of chromosomes] superfamily) homodimer, of escherichia coli markedly shrunk large dna molecules in the presence of hydrolyzable atp. in contrast, in the presence of adp or atp-gammas, the conformation of dna was almost not changed. this suggests that the atpase activity of subunit mukb is essential for sh ... | 2008 | 18326568 |
| orf334 in vibrio phage kvp40 plays the role of gp27 in t4 phage to form a heterohexameric complex. | kvp40 is a t4-related phage, composed of 386 open reading frames (orfs), that has a broad host range. here, we overexpressed, purified, and biophysically characterized two of the proteins encoded in the kvp40 genome, namely, gp5 and orf334. homology-based comparison between kvp40 and its better-characterized sister phage, t4, was used to estimate the two kvp40 proteins' functions. kvp40 gp5 shared significant homology with t4 gp5 in the n- and c-terminal domains. unlike t4 gp5, kvp40 gp5 lacked ... | 2008 | 18326574 |
| [effect of isoflurane delayed preconditioning on myocardial ischemia reperfusion injury in rabbits]. | to investigate the protective effect of isoflurane delayed preconditioning on myocardial ischemia reperfusion injury and the potential mechanism in rabbits. | 2008 | 18326909 |
| effect of hypothyroidism on the purinergic responses of corpus cavernosal smooth muscle in rabbits. | several studies have reported evidence of hormonal abnormalities in 25-35% of impotent men. hypothyroidism has been reported to occur in 6% of impotent men. in the present study, we examined purinergic relaxation responses in hypothyroidism in an experimental rabbit model and compared them with controls to evaluate the possible involvement of the purinergic pathway. | 2008 | 18327655 |
| a review of dna repair and possible dna-repair adjuvants and selected natural anti-oxidants. | few other organs have the environmental exposure-neoplasia relationship that has been observed between epithelial cutaneous malignancy and uvb exposure. a significant dna type of defective linking of dna nucleotides involves pyrimidine dimers. important insight into the molecular processes that affect the response of cells to uvb have been provided by the study of rare inherited diseases characterized by dna repair defects. nucleotide excision repair is the best characterized of these and its im ... | 2007 | 18328204 |
| [mouth floor and mobile tongue epidermoid carcinomas thickness: prognostic value]. | most cancers of the oral cavity are epidermoid carcinomas. the prognosis is made on the patient's general health status and the tumoral stage. the uicc tnm staging classification system is one of the most important factors taken in consideration for the prognosis. but this classification in oral epidermoid carcinomas does not include the tumor thickness (except for t4 tumors). several studies demonstrated that tumor thickness could influence the prognosis in epidermoid carcinoma and other types ... | 2008 | 18328517 |
| fibril formation of hsp10 homologue proteins and determination of fibril core regions: differences in fibril core regions dependent on subtle differences in amino acid sequence. | heat shock protein 10 (hsp10) is a member of the molecular chaperones and works with hsp60 in mediating various protein folding reactions. groes is a representative protein of hsp10 from escherichia coli. recently, we found that groes formed a typical amyloid fibril from a guanidine hydrochloride (gdn-hcl) unfolded state at neutral ph. here, we report that other hsp10 homologues, such as human hsp10 (hhsp10), rat mitochondrial hsp10 (rhsp10), gp31 from t4 phage, and hsp10 from the hyperthermophi ... | 2008 | 18329043 |
| [relevance of endoglin (cd105) vegf and p53 with invasion metastasis and prognosis of laryngeal carcinoma]. | to evaluate the clinical significance of microvessel density (mvd) and investigate the relationship of endoglin (cd105), vegf and p53 protein and their significance of clinical pathology. | 2007 | 18330257 |
| the multiple benefits of minimally invasive spinal surgery: results comparing transforaminal lumbar interbody fusion and posterior lumbar fusion. | minimally invasive transforaminal lumbar interbody fusion (tlif) offers equivalent postoperative fusion rates compared to posterior lumbar fusion (plf) and minimizes the amount of iatrogenic injury to the spinal muscles. the objective of this study was to examine the difference in pain perception, stress, mood disturbance, quality of life, and immunological indices throughout the perioperative course among patients undergoing tlif and plf. a prospective, nonrandomized descriptive design was used ... | 2008 | 18330408 |
| [peripheral blood t-lymphocyte and t-lymphocyte subset ratios before and after treatment in schizophrenia patients not taking antipsychotic medication]. | immune system abnormalities in schizophrenia have been previously studied. according to the present point of view, an infection or autoimmune process might be occurring in the form of cellular and/or humoral immune system abnormalities in schizophrenia. furthermore, several effects of antipsychotic medication on the immunological profile of schizophrenic patients have been demonstrated. the present study aimed to compare the total t-lymphocytes level and the t-lymphocyte subset ratios in schizop ... | 2008 | 18330738 |
| staging accuracy of esophageal cancer by endoscopic ultrasound: a meta-analysis and systematic review. | to evaluate the accuracy of endoscopic ultrasound (eus) in the staging of esophageal cancer. | 2008 | 18330935 |
| hypoechoic thyroid nodules on ultrasound 4 years after prenatal exposure to radioiodine: resolution with thyroxine therapy. | we describe an infant inadvertently exposed to radioiodine at 17 weeks gestation. his mother had received 400 mbq of (131)i for hyperthyroidism (total t4 178 nmol/l, thyroid stimulating hormone (tsh) <0.1 mu/l, 4-h (131)i uptake 16%). following cordocentesis at 27 weeks (free t4 12.7 pmol/l, tsh 35.4 mu/l) intra-amniotic thyroxine was withheld and a male infant was born at 39 weeks gestation, birthweight 3520 g. cord tsh was low (0.1 mu/l), total t4 151 nmol/l on day 4, the mother having receive ... | 2008 | 18331366 |
| laryngeal chondritis induced by c3-4 osteophyte following supracricoid laryngectomy with cricohyoidoepiglottopexy: report of two cases. | we have performed supracricoid laryngectomy with cricohyoidoepiglottopexy or with cricohyoidopexy for tumour (t) stage t2 and t3 laryngeal cancer cases and some t4 cases. we report the clinical symptoms and management, using this technique to avoid complications. | 2008 | 18331655 |
| major hepatectomy for isolated metastases from gastric adenocarcinoma. | liver metastases from gastric adenocarcinoma denote a poor prognosis. most gastric metastases will be diffuse, and for these chemotherapy remains the only useful treatment modality. the treatment of isolated liver metastases is still unclear. the japanese literature has reported good results with surgical resection, but western series were unable to achieve the same results. we report our results with resection of liver metastases from gastric cancer in nine patients. | 2003 | 18332993 |
| identification of dio2 as a new susceptibility locus for symptomatic osteoarthritis. | osteoarthritis [mim 165720] is a common late-onset articular joint disease for which no pharmaceutical intervention is available to attenuate the cartilage degeneration. to identify a new osteoarthritis susceptibility locus, a genome-wide linkage scan and combined linkage association analysis were applied to 179 affected siblings and four trios with generalized osteoarthritis (the garp study). we tested, for confirmation by association, 1478 subjects who required joint replacement and 734 contro ... | 2008 | 18334578 |
| effects of the hormones of the thyroid axis on the vitamin k-dependent plasma factors of blood coagulation (ii, vii, ix, and x). | the hormonal regulation of haemostasis is a problem which has not received much attention. the data concerning the influence of hormones from the hypothalamic-pituitary-thyroid axis are scarce, contradictory and based mainly on clinical observations. the objective of the current research is to study the influence of the thyrotropin releasing hormone (trh), thyroid stimulating hormone (tsh), triiodothyronine (t3) and thyroxin (t4) on the activity level of the vitamin k-dependent plasma factors of ... | 2008 | 18336749 |
| estrone sulfate (e1s), a prognosis marker for tumor aggressiveness in prostate cancer (pca). | seeking insight into the possible role of estrogens in prostate cancer (pca) evolution, we assayed serum e2, estrone (e1), and estrone sulfate (e1s) in 349 pca and 100 benign prostatic hyperplasia (bph) patients, and in 208 control subjects in the same age range (50-74 years). e1 (pmol/l+/-s.d.) and e1s (nmol/l+/-s.d.) in the pca and bph patients (respectively 126.1+/-66.1 and 2.82+/-1.78, and 127.8+/-56.4 and 2.78+/-2.12) were significantly higher than in the controls (113.8+/-47.6 and 2.11+/-0 ... | 2008 | 18337090 |
| acute spontaneous spinal subdural hematoma in a patient with bilateral incarcerated inguinal hernia. | acute spinal subdural hematoma is an infrequent and devastating condition that occurs mostly in patients with coagulopathy or receiving anticoagulants. it may also develop after trauma, spinal surgery or iatrogenically (lumbar puncture and/or spinal anaesthesia). spinal vascular malformations or spinal tumours can also be the origins of subdural hematomas. however, acute spinal subdural hematomas, which are not associated with these risk factors, are seen even more infrequently. in this report, ... | 2008 | 18337142 |
| feasibility of the sentinel node biopsy in anal cancer. | anal cancer is a rare neoplasm. according to a european organization for research and treatment of cancer multivariate analysis, synchronous inguinal lymph node metastasis occurs in 10-25% of patients and constitutes an independent prognostic factor for local failure and overall mortality. | 2009 | 18337684 |
| preoperative assessment for pituitary surgery. | evaluation of pituitary function is essential before pituitary surgery. in hyperprolactinaemic patients with a pituitary macrolesion, tumoral secretion of prolactin must be distinguished from 'disconnection' hyperprolactinaemia; serum prolactin >200 mcg/l is virtually diagnostic of a macroprolactinoma whereas levels <80 mcg/l usually indicate 'disconnection'. the prolactin 'hook effect' should be excluded. a minimum set of pre-operative endocrine tests should include serum electrolytes, cortisol ... | 2008 | 18338267 |
| thyroidectomy for graves' hyperthyroidism. retrospective study of patients' appreciation. | to retrospectively investigate the patients' views of surgical treatment of graves' hyperthyroidism. | 2007 | 18338549 |
| fibrinolysis or hypercoagulation during radical prostatectomy? an evaluation of thrombelastographic parameters and standard laboratory tests. | radical prostatectomy is at high risk for intraoperative and postoperative bleeding due to surgical trauma, release of urokinase and tissue type plasminogen activator. we conducted this prospective, observational multi-centre study to assess the degree of systemic fibrinolysis or hypercoagulation in the perioperative period. we studied serial changes in standard laboratory values and in thrombelastographic (teg; haemoscope corporation, skokie, il, usa) parameters including lysis at 30 and 60 min ... | 2008 | 18339213 |
| clinicopathologic characteristics and prognosis for young gastric adenocarcinoma patients after curative resection. | conflicting results from previous studies on gastric adenocarcinoma (gc) in young patients have led to controversy surrounding the prognosis for young gc patients. | 2008 | 18340495 |
| treatment results for 84 patients with base of tongue cancer. | for t2 tumors, surgery was indicated if functional preservation was possible. for t3/t4 tumors, the rate of primary disease control was not high and surgery frequently involved total laryngectomy. points that surgeons must heed when performing such surgery were delineated. | 2007 | 18340583 |
| carcinoid tumor of the larynx: clinical analysis of 33 cases in japan. | in regard to the treatment of carcinoid tumor of the larynx, irradiation is not effective and tumor excision with a minimum surgical margin is associated with a high risk of local recurrence. lymph node metastases to the neck are associated with worsening of the prognosis. to improve the survival rate, primary resection with a sufficient surgical margin (e.g. partial laryngectomy) and (elective) neck dissection is recommended, even for patients with early stage carcinoid tumors of the larynx. | 2007 | 18340586 |
| thyroid function in preterm infants 27-29 weeks of gestational age during the first four months of life: results from a prospective study comprising 80 preterm infants. | assessment of thyroid function in preterm neonates (ptn) 27-29 weeks of gestational age. | 2007 | 18341087 |
| altered intestinal absorption of l-thyroxine caused by coffee. | to report eight case histories, and in vivo and in vitro studies showing coffee's potential to impair thyroxine (t4) intestinal absorption. | 2008 | 18341376 |
| an audit of outcomes of a series of periampullary carcinomas. | non-pancreatic periampullary carcinoma such as ampullary carcinoma (ampca), distal cholangiocellular carcinoma (cholca) and duodenal carcinoma (duoca) have a better prognosis than pancreatic head adenocarcinoma (panca). this study describes the outcome and parameters, which predict survival of non-pancreatic periampullary carcinoma after resection. | 2009 | 18343082 |
| concomitant boost radiotherapy compared with conventional radiotherapy in squamous cell carcinoma of the head and neck--a phase iii trial from a single institution in india. | to test the efficacy of an accelerated fractionation schedule (concomitant boost) against standard conventional fractionation in squamous cell carcinomas of the head and neck region in our patient population. | 2008 | 18343310 |
| [cervicomanubrial route for the ventral upper thoracic spine: technical note about six cases]. | ventrolateral cervicotomy provides a narrowed working space for surgical management of upper thoracic spine. we report our experience about ventral upper thoracic spinal cord decompression with reconstruction and plating via the cervicomanubrial route. six patients (24 to 75 years old) were operated on by the same operator (ln) by cervicomanubriotomy from 2002 to 2007 for upper thoracic spinal cord compression (one case of pott's disease, three cases of metastases, one fracture, one invasive hem ... | 2008 | 18343460 |
| the virulence regulator sae of staphylococcus aureus: promoter activities and response to phagocytosis-related signals. | the two-component system saers of staphylococcus aureus is closely involved in the regulation of major virulence factors. however, little is known about the signals leading to saers activation. a total of four overlapping transcripts (t1 to t4) from three different transcription starting points are expressed in the sae operon. we used a beta-galactosidase reporter assay to characterize the putative promoter regions within the saers upstream region. the main transcript t2 is probably generated by ... | 2008 | 18344360 |
| [transient neonatal hypothyroidism due to amiodarone administration during pregnancy--two cases report and review of literature]. | introduction: amiodarone (amd) is an antiarrhythmic agent which contains 37% of iodine. it can reach the fetus by transplacental passage and induce transient congenital hypothyroidism (tch). we report two cases of tch caused by gestational exposure to amd, detected by the newborn screening program for congenital hypothyroidism of the state of paraná-brazil. clinical case 1 (c1): neonatal tsh value was 78.2 mu/l (normal<15 mu/l). amd had been given to the mother during pregnancy to treat maternal ... | 2008 | 18345406 |
| significant inverse relationship between serum free t4 concentration and body mass index in euthyroid subjects: differences between smokers and nonsmokers. | there are conflicting data regarding the relationship between thyroid function and body mass index (bmi) in euthyroid subjects, and it is uncertain whether tobacco smoking modifies this relationship. the objective of this study was to examine the relationships between thyroid function, bmi and smoking in euthyroid subjects. | 2008 | 18346211 |
| blocking noise but not music lowers bispectral index scores during sedation in noisy operating rooms. | to determine whether playing music or blocking noise can reduce bispectral index (bis) values during propofol sedation. | 2008 | 18346603 |
| high pressure liquid chromatographic analysis of in vivo metabolites of n-(substituted phenyl)-n'-(1,3,5-trimethyl pyrazole-4-yl)thioureas in rats. | the aim of this study was to investigate the in vivo metabolism of n-(substituted phenyl)-n'-(1,3,5-trimethylpyrazole-4-yl)thioureas (substrate) as model compounds in rats via hplc. the substrates, n-(4-fluoro/chlorophenyl)-n'-(1,3,5-trimethylpyrazole-4-yl)thioureas (t2 and t3), and their possible metabolites were synthesized and the structures of the compounds were elucidated both by spectral and elemental analysis. substrates were dissolved in 5% gum arabic and administered 100 mg/kg intraperi ... | 2007 | 18348472 |
| imaging of idiopathic spinal cord herniation. | idiopathic spinal cord herniation, unlike spinal cord herniation with a known traumatic or postoperative origin, is a relatively rare condition; however, it has been diagnosed and reported with increasing frequency in recent years. such herniation most often occurs in the thoracic spine, between the t4 and t7 vertebrae. brown-séquard syndrome is the most frequently reported clinical feature. early manifestations may include numbness and decreased temperature sensation in the legs, gait disturban ... | 2008 | 18349454 |
| phase ii study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer. | this multicentre phase ii study evaluated the efficacy and safety of preoperative capecitabine plus oxaliplatin and radiotherapy (rt) in patients with locally advanced rectal cancer (t3/t4 rectal adenocarcinoma with or without nodal involvement). treatment consisted of one cycle of xelox (capecitabine 1000 mg m(-2) bid on days 1-14 and oxaliplatin 130 mg m(-2) on day 1), followed by rt (1.8 gy fractions 5 days per week for 5 weeks) plus capox (capecitabine 825 mg m(-2) bid on days 22-35 and 43-5 ... | 2008 | 18349837 |
| preoperative t staging of colorectal cancer by ct colonography. | this study was designed to estimate the accuracy of ct colonography for the assessment of t stage in colorectal cancer. | 2008 | 18350337 |
| [blood biochemical parameters of tilted primates periodically subjected to gravitational stimuli]. | head-down tilting of primates (hot) is a universal method of studying the hypokinetic syndrome effects on functionality of various body systems. clinical biochemical blood assay was performed in a 25-day hdt experiment (-5 degrees) with 11 macaca rhesus. one group of animals was kept tilted all the time through, whereas the other was periodically returned into the orthostatic position for 30 to 120 minutes 4-5 times a week. dry chemistry was employed in biochemical analysis of blood serum and en ... | 2007 | 18350838 |
| comparison of selected diagnostic parameters in african grey parrots (psittacus erithacus) with normal plumage and those exhibiting feather damaging behavior. | feather damaging behavior is a common problem in african grey parrots (psittacus erithacus). to determine if differences in clinical test results could be detected in parrots with feather damaging behavior (fdb), we studied 51 parrots, including 24 with fdb, with a variety of diagnostic tests. a predictable stress hemogram was found after administration of thyroid-stimulating hormone in both normal birds and birds with fdb. birds with fdb had significantly lower lymphocyte counts and higher hete ... | 2007 | 18351004 |
| hemodynamic effects of passive leg raising: an echocardiographic study in patients with shock. | to determine the effects of passive leg raising (plr) on hemodynamics and on cardiac function according to the preload dependency defined by the superior vena cava collapsibility index (deltasvc). | 2008 | 18351322 |
| effects of thyroidectomy, t4, and ditpa replacement on brain blood vessel density in adult rats. | in hypothyroid patients, altered microvascular structure and function may affect mood and cognitive function. we hypothesized that adult male hypothyroid rats will have significantly lower forebrain blood vessel densities (bvd) than euthyroid rats and that treatment with 3,5-diiothyroprionic acid (ditpa) (a thyroid hormone analog) or thyroxine (t(4)) will normalize bvds. the euthyroid group received no thyroidectomy or treatment. the other three groups received thyroidectomies and pellets. the h ... | 2008 | 18353884 |
| effects of plant genotype and growth stage on the structure of bacterial communities associated with potato (solanum tuberosum l.). | the effects of genotype, plant growth and experimental factors (soil and year) on potato-associated bacterial communities were studied. cultivars achirana inta, désirée, merkur and transgenic désirée line dl12 (containing t4 lysozyme gene) were assessed in two field experiments. cross-comparisons between both experiments were made using désirée plants. culture-dependent and -independent approaches were used to demonstrate effects on total bacterial, actinobacterial and pseudomonas communities in ... | 2008 | 18355298 |
| lipid profile in different degrees of hypothyroidism and effects of levothyroxine replacement in mild thyroid failure. | the aim of this study was to evaluate the lipid profile of patients with different degrees of hypothyroidism and the effect of levothyroxine replacement in subclinical hypothyroidism (sh). initially, a cross-sectional study was performed with 226 participants [sh = 133 participants, manifest hypothyroidism (mh) = 23 participants, and euthyroidism (eu) = 70 participants]. the mean levels of atherogenic lipid variables were greater in mh than in sh and were greater in sh than in eu, although the d ... | 2008 | 18355770 |
| locoregionally advanced head and neck cancer treated with primary radiotherapy: a comparison of the addition of cetuximab or chemotherapy and the impact of protocol treatment. | the addition of platinum-based chemotherapy (chrt) or cetuximab (exrt) to concurrent radiotherapy (rt) has resulted in improved survival in phase iii studies for locoregionally advanced head and neck cancer (lahnc). however the optimal treatment regimen has not been defined. a retrospective study was performed to compare outcomes in patients who were treated definitively with exrt or chrt. | 2008 | 18355979 |
| uncommon breast tumor attenuation artifact on radionuclide ventriculography. | a 39-year-old woman with locally advanced left breast cancer (t4 n0 m0) underwent equilibrium radionuclide ventriculography for baseline assessment of left ventricular function before neoadjuvant chemotherapy. the left ventricular ejection fraction was 76% at 75 beats per minute, without localized wall motion abnormality. in the best septal left anterior oblique projection, a large photopenic "halo" surrounded the cardiac chambers, mimicking a pericardial effusion. in fact, this aspect resulted ... | 2008 | 18356673 |
| selenium analogues of antithyroid drugs--recent developments. | thyroxine (t4), the main secretory hormone of the thyroid gland, is produced on thyroglobulin by thyroid peroxidase (tpo)/h(2)o(2)/iodide system and deiodinated to its active form (t3) by a selenocysteine-containing enzyme, iodothyronine deiodinase (id). the activation of thyroid-stimulating hormone (tsh) receptor by auto-antibodies leads to 'hyperthyroidism', a life-threatening disease which is treated by antithyroid drugs such as 6-propyl-2-thiouracil (ptu) and methimazole (mmi). the present r ... | 2008 | 18357551 |
| in vitro characterization of a murine oligodendrocyte precursor cell line (bo-1) following spontaneous immortalization. | the understanding of oligodendrocyte differentiation is crucial for designing therapies of demyelinating diseases. oligodendrocyte precursor cells are of particular interest in this context, because of their remyelinating potential. permanent cell lines, which are a versatile tool for studying oligodendrocyte physiology, have been so far mainly established from the rat cns. in the present study, we describe a novel murine oligodendrocyte precursor cell line (bo-1) established by spontaneous immo ... | 2008 | 18358665 |
| serum concentrations of estradiol and free t4 are inversely correlated with sperm dna damage in men from an infertility clinic. | sperm dna damage adversely affects male fertility and contributes to poorer embryo development and lower pregnancy rates. endogenous hormones are critical to spermatogenesis and maintenance of male reproductive function and likely play an important role in human sperm dna integrity, but this relationship is not fully understood. the present study measured serum hormone levels and sperm dna damage with the neutral comet assay in 362 male partners of infertile couples. when sperm concentration and ... | 2008 | 18359755 |
| differential mechanisms of binding of anti-sigma factors escherichia coli rsd and bacteriophage t4 asia to e. coli rna polymerase lead to diverse physiological consequences. | anti-sigma factors escherichia coli rsd and bacteriophage t4 asia bind to the essential housekeeping sigma factor, sigma(70), of e. coli. though both factors are known to interact with the c-terminal region of sigma(70), the physiological consequences of these interactions are very different. this study was undertaken for the purpose of deciphering the mechanisms by which e. coli rsd and bacteriophage t4 asia inhibit or modulate the activity of e. coli rna polymerase, which leads to the inhibiti ... | 2008 | 18359804 |
| [comparative study of the resistance of bacteriophaget4, phix174d, ms2 and f2 to gamma radiation]. | to screen the suitable bacteriophage as virus indicator in irradiation sterilization. | 2008 | 18361821 |
| thoracic spinal epidural abscess caused by salmonella typhi. | a 56-year-old man presented with a rare spinal epidural abscess manifesting as attacks of back pain associated with fever, weight loss, generalized weakness and fatigability, and constipation. he had multiple skin pustules in the last 4 months treated with oral amoxicillin. he had suffered diabetes mellitus for the last 5 years and was insulin dependent. physical examination found slight paraparesis with sensory loss around the nipple and sphincteric urgency, and diabetic retinopathy. magnetic r ... | 2008 | 18362463 |
| correlates and outcomes of tumor adherence in resected colonic and rectal cancers. | the aims of this study were to examine the associations between tumor adherence and other operative findings, postoperative complications, recurrence, and survival after resection of colorectal cancer. | 2008 | 18362628 |
| resistance to thyroid hormone with missense mutation (v349m) in the thyroid hormone receptor beta gene. | resistance to thyroid hormone (rth) is a syndrome characterized by reduced sensitivity to the thyroid hormone. it is generally caused by mutations in the thyroid hormone receptor beta (tr beta) gene. on the basis of its clinical features, two different forms of this syndrome have been described: generalized resistance and pituitary resistance. a total of 122 tr beta gene mutations have been identified thus far. a 38-year-old woman presented with intermittent palpitation. thyroid function tests r ... | 2008 | 18363280 |
| thyroglobulin measurement before rhtsh-aided 131i ablation in detecting metastases from differentiated thyroid carcinoma. | thyroidectomy followed by administration of large activities of 131-iodine ((131)i) is the treatment of choice for differentiated thyroid carcinoma (dtc). the serum thyroglobulin (tg) measurement during hypothyroidism (offt4-tg), just before radioiodine thyroid ablation, has proved to be effective for predicting persistent/recurrent disease. however, the tg measurement cannot be used as a corresponding value for pre-ablative offt4-tg when recombinant human tsh (rhtsh) is used as stimulus before ... | 2008 | 18363882 |
| quantitative analysis of spinal curvature in 3d: application to ct images of normal spine. | the purpose of this study is to present a framework for quantitative analysis of spinal curvature in 3d. in order to study the properties of such complex 3d structures, we propose two descriptors that capture the characteristics of spinal curvature in 3d. the descriptors are the geometric curvature (gc) and curvature angle (ca), which are independent of the orientation and size of spine anatomy. we demonstrate the two descriptors that characterize the spinal curvature in 3d on 30 computed tomogr ... | 2008 | 18364545 |
| transrectal ultrasonography and magnetic resonance imaging in the staging of rectal cancer. effect of experience. | to evaluate the effect of experience on preoperative staging of rectal cancer using magnetic resonance imaging (mri) and transrectal ultrasound (trus). | 2008 | 18365909 |
| transarterial nephrectomy: the current status of experimental and clinical studies. | open nephrectomy is associated with significant morbidity. for several years, minimally invasive alternatives have been developed such as laparoscopic nephrectomy or transarterial renal ablation. this paper focuses on the different principles of vaso-occlusion and further improvements of the technique such as capillary chemoembolization in experimental as well as clinical studies. | 2008 | 18366320 |
| nasopharyngectomy for recurrent nasopharyngeal carcinoma: a review of 53 patients and prognostic factors. | salvage surgery is a justified treatment for primary recurrence of nasopharyngeal carcinoma (npc). skull base surgery can play a role in rescuing patients with more advanced local recurrence of npc. | 2008 | 18368585 |
| whole-body 18 fdg pet/ct imaging for lymph node and metastatic staging of conjunctival melanoma. | to evaluate 18-fluoro-2-deoxyglucose (fdg) whole-body positron emission tomography/computed radiographic tomography (pet/ct) for lymph node and metastatic staging of patients with conjunctival melanoma. | 2008 | 18369064 |
| self evaluation of communication experiences after laryngeal cancer - a longitudinal questionnaire study in patients with laryngeal cancer. | aim of this longitudinal study was to investigate the sensitivity to change of the swedish self evaluation of communication experiences after laryngeal cancer questionnaire (the s-secel), addressing communication dysfunction in patients treated for laryngeal cancer. previous studies have highlighted the need for more specific questionnaires for this purpose. | 2008 | 18371189 |
| [the results of the "tiromobil" epidemiological trial of pregnant women in the russian federation]. | to study structural and functional changes in the thyroid gland (tg) in pregnant women living in iodine-deficiency regions; to evaluate efficacy of prophylactic measures. | 2008 | 18372603 |
| thyroid hormones modulate occurrence and termination of ventricular fibrillation by both long-term and acute actions. | thyroid hormones (th) are powerful modulators of heart function, but their arrhythmogenic effects are less elucidated. we have examined both acute and long-term action of th on the heart susceptibility to the ventricular fibrillation (vf) and on the heart ability to terminate vf and restore a sinus rhythm. triiodothyronine (t3) was applied in the range of 10(-9)-10(-6) mol/l in acute experiments using isolated perfused aged (14-month-old) guinea pig hearts. l-thyroxine (t4) was applied in the do ... | 2008 | 18373387 |
| clinical and endorectal ultrasound staging of circumferential rectal cancers. | circumferential rectal cancers present at a more advanced stage than those located in a single quadrant. although accurate staging is an important aspect of the preoperative management of the patient with a rectal cancer, the clinical and radiological staging of this subgroup of rectal cancer patients has been poorly studied. all patients with a rectal cancer were assessed clinically (by digital rectal examination and rigid sigmoidoscopy) before the radiological assessment by endorectal ultrasou ... | 2008 | 18373808 |
| cardiovascular and metabolic responses during functional electric stimulation cycling at different cadences. | to determine the influence of pedaling cadence on cardiorespiratory responses and muscle oxygenation during functional electric stimulation (fes) leg cycling. | 2008 | 18374003 |
| adenocarcinoma of the esophagogastric junction: the pattern of metastatic lymph node dissemination as a rationale for elective lymphatic target volume definition. | regional nodal metastasis after neoadjuvant chemoradiation of adenocarcinoma of the esophagogastric junction (aeg) predicts survival. we aimed to clarify the lymph node (ln) distribution of aeg according to location of the tumor mass and invasion of neighboring areas for the selection of radiotherapy planning target volume (ptv) margins. | 2008 | 18374226 |
| acr appropriateness criteria on resectable rectal cancer: expert panel on radiation oncology--rectal/anal cancer. | in what arguably may be the most pivotal recent trial in the area of resectable rectal cancer management, a randomized trial from germany has established a regimen of preoperative chemoradiotherapy and surgery followed by additional cycles of chemotherapy alone as the standard of care for clinical stages t3 or t4, or for node-positive rectal cancer. other clinical studies from the united states, europe, and asia have also influenced the treatment strategies of operable rectal cancer, as various ... | 2008 | 18374227 |
| carbon ion radiation therapy for primary renal cell carcinoma: initial clinical experience. | renal cell carcinoma (rcc) is known as a radioresistant tumor, and there are few reports on radiotherapy for primary rcc. we evaluated the efficacy of carbon ion radiotherapy (cirt) for patients with rcc. | 2008 | 18374507 |