| structure-guided discovery of the metabolite carboxy-sam that modulates trna function. | the identification of novel metabolites and the characterization of their biological functions are major challenges in biology. x-ray crystallography can reveal unanticipated ligands that persist through purification and crystallization. these adventitious protein-ligand complexes provide insights into new activities, pathways and regulatory mechanisms. we describe a new metabolite, carboxy-s-adenosyl-l-methionine (cx-sam), its biosynthetic pathway and its role in transfer rna modification. the ... | 2013 | 23676670 |
| cysteine-conjugated metabolite of ginger component [6]-shogaol serves as a carrier of [6]-shogaol in cancer cells and in mice. | shogaols, a series of major constituents in dried ginger (zingiber officinale), show high anticancer potencies. previously, we reported that a major metabolite resulting from the mercapturic acid pathway, 5-cysteinyl-[6]-shogaol (m2), showed comparable growth inhibitory effects toward cancer cells to [6]-shogaol (6s). here, we probe the mechanism by which m2 exerts its bioactivity. we utilized a series of chemical stability tests in conjunction with bioassays to show that thiol-conjugates displa ... | 2013 | 23638641 |
| atypical mycobacterial exit-site infection and peritonitis in peritoneal dialysis patients on prophylactic exit-site gentamicin cream. | we report 9 cases of exit-site infection and continuous ambulatory peritoneal dialysis peritonitis associated with atypical mycobacteria. all patients had been using topical gentamicin cream as prophylaxis for exit-site infection before the onset of these infections. gentamicin cream is postulated to be a potential risk factor for atypical mycobacterial infection because of selective pressure on other micro-organisms. the microbiology of atypical mycobacteria and the treatment for atypical mycob ... | 2013 | 23032088 |
| characterising the biology of novel lytic bacteriophages infecting multidrug resistant klebsiella pneumoniae. | members of the genus klebsiella are among the leading microbial pathogens associated with nosocomial infection. the increased incidence of antimicrobial resistance in these species has propelled the need for alternate/combination therapeutic regimens to aid clinical treatment. bacteriophage therapy forms one of these alternate strategies. | 2013 | 23537199 |
| inositol, glycogen, insulin, and six nobelists. | | 2013 | 23515311 |
| directed evolution: past, present and future. | directed evolution, the laboratory process by which biological entities with desired traits are created through iterative rounds of genetic diversification and library screening or selection, has become one of the most useful and widespread tools in basic and applied biology. from its roots in classical strain engineering and adaptive evolution, modern directed evolution came of age twenty years ago with the demonstration of repeated rounds of pcr-driven random mutagenesis and activity screening ... | 2013 | 25733775 |
| characterization of thiol-conjugated metabolites of ginger components shogaols in mouse and human urine and modulation of the glutathione levels in cancer cells by [6]-shogaol. | shogaols, a series of major constituents in dried ginger with the most abundant being [6]-, [8]-, and [10]-shogaols, show much higher anticancer potencies than gingerols. previously, we reported the mercapturic acid pathway as a major metabolic route for [6]-shogaol in mice. however, it is still unclear how the side chain length affects the metabolism of shogaols and how shogaols are metabolized in humans. | 2013 | 23322393 |
| the first genotype determination of acanthamoeba potential threat to human health, isolated from natural water reservoirs in poland. | different species of amoebae belonging to the genus acanthamoeba are widely distributed in many parts of the world and known as free-living organisms. some strains of the protozoans may exist as parasites and cause risk to human health as causative agents of serious human diseases. currently, in poland, there is no sufficient information about the distribution of acanthamoeba strains and their genotypes in the environment. therefore, 20 environmental surface water samples were collected from dif ... | 2014 | 24770720 |
| an expanded set of fluorogenic sulfatase activity probes. | fluorogenic probes that are activated by an enzymatic transformation are ideally suited for profiling enzyme activities in biological systems. here, we describe two fluorogenic enzyme probes, 3-o-methylfluorescein-sulfate and resorufin-sulfate, that can be used to detect sulfatases in mycobacterial lysates. both probes were validated with a set of commercial sulfatases and used to reveal species-specific sulfatase banding patterns in a gel-resolved assay of mycobacterial lysates. the fluorogenic ... | 2014 | 24764280 |
| habitat discrimination by gravid anopheles gambiae sensu lato--a push-pull system. | the non-random distribution of anopheline larvae in natural habitats suggests that gravid females discriminate between habitats of different quality. whilst physical and chemical cues used by culex and aedes vector mosquitoes for selecting an oviposition site have been extensively studied, those for anopheles remain poorly explored. here the habitat selection by anopheles gambiae sensu lato (s.l.), the principal african malaria vector, was investigated when presented with a choice of two infusio ... | 2014 | 24693951 |
| oral administration of bovine milk from cows hyperimmunized with intestinal bacterin stimulates lamina propria t lymphocytes to produce th1-biased cytokines in mice. | the goal of this study was to examine the effects of oral administration of bovine milk from cows hyperimmunized with a proprietary bacterin (immune milk "sustaina") on mucosal immunity in the intestine of adult mice. c57bl/6 mice were orally given immune or control milk for two weeks, and then lymphocyte population and the cytokine production in lamina propria of colon in normal mice and mice induced colitis by dextran sulphate sodium (dss) were detected. we found that the levels of ifn-γ and i ... | 2014 | 24686517 |
| autocrine/paracrine dopamine in the salivary glands of the blacklegged tick ixodes scapularis. | dopamine (da) is known to be the most potent activator of tick salivary secretion, which is an essential component of successful tick feeding. we examined the quantitative changes of catecholamines using a method coupling high-pressure liquid chromatography with electrochemical detection (hplc-ecd). we also investigated the levels of catecholamines conjugated to other molecules utilising appropriate methods to hydrolyse the conjugates. three different biological samples, salivary glands, syngang ... | 2014 | 24503219 |
| reduction of meckelin leads to general loss of cilia, ciliary microtubule misalignment and distorted cell surface organization. | meckelin (mks3), a conserved protein linked to meckel syndrome, assists in the migration of centrioles to the cell surface for ciliogenesis. we explored for additional functions of mks3p using rna interference (rnai) and expression of flag epitope tagged protein in the ciliated protozoan paramecium tetraurelia. this cell has a highly organized cell surface with thousands of cilia and basal bodies that are grouped into one or two basal body units delineated by ridges. the highly systematized natu ... | 2014 | 24484742 |
| induction of lung cancer cell apoptosis through a p53 pathway by [6]-shogaol and its cysteine-conjugated metabolite m2. | dietary chemoprevention of cancer offers the possibility to suppress or inhibit cancer growth before it develops into more advanced and lethal stages. to this end, identification of novel compounds and their mechanisms of action is constantly needed. in this study, we describe that a major component of dry ginger (zingiber officinalis), [6]-shogaol (6s), can be quickly metabolized in a549 human lung cancer cell line. one of the resulting metabolites, the cysteine-conjugated 6s (m2), exhibits tox ... | 2014 | 24446736 |
| first case of propionibacterium acnes urinary tract infection in a dog. | propionibacterium acnes has been rarely isolated as a commensal from dogs, but there is little evidence of pathogenicity. urinary tract infections are common in dogs and are typically caused by various commensal bacteria. here we present the first case report of a urinary tract infection caused by p. acnes. | 2015 | 26690238 |
| expression of lactate dehydrogenase in aspergillus niger for l-lactic acid production. | different engineered organisms have been used to produce l-lactate. poor yields of lactate at low ph and expensive downstream processing remain as bottlenecks. aspergillus niger is a prolific citrate producer and a remarkably acid tolerant fungus. neither a functional lactate dehydrogenase (ldh) from nor lactate production by a. niger is reported. its genome was also investigated for the presence of a functional ldh. the endogenous a. niger citrate synthase promoter relevant to a. niger acidogen ... | 2015 | 26683313 |
| pan-genomic analysis to redefine species and subspecies based on quantum discontinuous variation: the klebsiella paradigm. | various methods are currently used to define species and are based on the phylogenetic marker 16s ribosomal rna gene sequence, dna-dna hybridization and dna gc content. however, these are restricted genetic tools and showed significant limitations. | 2015 | 26420254 |
| bioprocess development for kefiran production by lactobacillus kefiranofaciens in semi industrial scale bioreactor. | lactobacillus kefiranofaciens is non-pathogenic gram positive bacteria isolated from kefir grains and able to produce extracellular exopolysaccharides named kefiran. this polysaccharide contains approximately equal amounts of glucose and galactose. kefiran has wide applications in pharmaceutical industries. therefore, an approach has been extensively studied to increase kefiran production for pharmaceutical application in industrial scale. the present work aims to maximize kefiran production thr ... | 2015 | 27298582 |
| bioprocess development for kefiran production by lactobacillus kefiranofaciens in semi industrial scale bioreactor. | lactobacillus kefiranofaciens is non-pathogenic gram positive bacteria isolated from kefir grains and able to produce extracellular exopolysaccharides named kefiran. this polysaccharide contains approximately equal amounts of glucose and galactose. kefiran has wide applications in pharmaceutical industries. therefore, an approach has been extensively studied to increase kefiran production for pharmaceutical application in industrial scale. the present work aims to maximize kefiran production thr ... | 2015 | 27298582 |
| distribution and gene mutation of enteric flora carrying β-glucuronidase among patients with colorectal cancer. | to explore the difference of distribution in intestinal flora among colorectal cancer patients and healthy controls and investigate characteristics and changes of sequences in beta-glucuronidase (β-glucuronidase, β-g). | 2015 | 26131106 |
| structure of n-formimino-l-glutamate iminohydrolase from pseudomonas aeruginosa. | n-formimino-l-glutamate iminohydrolase (hutf), from pseudomonas aeruginosa with a locus tag of pa5106 ( gi|15600299 ), is a member of the amidohydrolase superfamily. this enzyme catalyzes the deamination of n-formimino-l-glutamate to n-formyl-l-glutamate and ammonia in the histidine degradation pathway. the crystal structure of pa5106 was determined in the presence of the inhibitors n-formimino-l-aspartate and n-guanidino-l-glutaric acid at resolutions of 1.9 and 1.4 å, respectively. the structu ... | 2015 | 25559274 |
| homeostasis of metabolites in escherichia coli on transition from anaerobic to aerobic conditions and the transient secretion of pyruvate. | we have developed a method for rapid quenching of samples taken from chemostat cultures of escherichia coli that gives reproducible and reliable measurements of extracellular and intracellular metabolites by (1)h nmr and have applied it to study the major central metabolites during the transition from anaerobic to aerobic growth. almost all metabolites showed a gradual change after perturbation with air, consistent with immediate inhibition of pyruvate formate-lyase, dilution of overflow metabol ... | 2016 | 27853594 |
| emphysematous pyelitis and cystitis associated with vesicoureteral reflux in a diabetic dog. | a 12-year-old female dog with a 3-month history of poor response to diabetes treatment had an acute worsening of symptoms, including weakness and blindness. the dog had elevated blood glucose, alkaline phosphatase and urea concentration, hyposthenuria, glycosuria, hematuria, and pyuria. escherichia coli was isolated from the urine. radiographs and ultrasound examination showed that the dog had unilateral emphysematous pyelitis and concurrent cystitis associated with vesicoureteral reflux. | 2016 | 27041755 |
| emphysematous cholecystitis presenting as gas-forming liver abscess and pneumoperitoneum in a dialysis patient: a case report and review of the literature. | emphysematous cholecystitis is a rare variant of acute cholecystitis with a high mortality rate. the combination of emphysematous cholecystitis, liver abscess and pneumoperitoneum are even rarer. herein we present a case of emphysematous cholecystitis in a senile diabetic lady who had worsening hemodynamics while undergoing hemodialysis. | 2016 | 26932814 |
| draft genome assemblies of enterobacter aerogenes cdc 6003-71, enterobacter cloacae cdc 442-68, and pantoea agglomerans ua 0804-01. | the enterobacteriaceae are environmental and enteric microbes. we sequenced the genomes of two enterobacter reference strains, e. aerogenes cdc 6003-71 and e. cloacae cdc 442-68, as well as one near neighbor used as an exclusionary reference for diagnostics, pantoea agglomerans cdc ua0804-01. the genome sizes range from 4.72 to 5.55 mbp and have g+c contents from 54.6 to 55.1%. | 2014 | 25342683 |
| horizontol dissemination of tem- and shv-typr beta-lactamase genes-carrying resistance plasmids amongst clonical isolates of enterobacteriaceae. | the extended-spectrum β-lactamase (esbl)-producing bacteria have been isolated at increasing frequency worldwide. expression of esbl is often associated with multidrug resistance and dissemination by resistance plasmids. during a two-month period in 2000, 133 clinical isolates of enterobacterial strains were randomly collected from outpatients and inpatients at a university hospital in turkey. the esbl producing strains were determined by double-disk synergy (dds) testing. twenty esbl producing ... | 2008 | 24031280 |
| molecular characteristics of extended-spectrum beta-lactamases and qnr determinants in enterobacter species from japan. | the incidence of extended-spectrum β-lactamases (esbls) has been increasing worldwide, but screening criteria for detection of esbls are not standardized for ampc-producing enterobacteriaceae such as enterobacter species. in this study, we investigated the prevalence of esbls and/or ampc β-lactamases in japanese clinical isolates of enterobacter spp. and the association of plasmid-mediated quinolone resistance (pmqr) determinants with esbl producers. a total of 364 clinical isolates of enterobac ... | 2012 | 22719857 |
| carbapenem resistance among enterobacter species in a tertiary care hospital in central india. | objective. to detect genes encoding carbapenem resistance among enterobacter species in a tertiary care hospital in central india. methods. bacterial identification of enterobacter spp. isolates from various clinical specimens in patients admitted to intensive care units was performed by routine conventional microbial culture and biochemical tests using standard recommended techniques. antibiotic sensitivity test was performed by standard kirby bauer disc diffusion technique. pcr amplification a ... | 2014 | 25180095 |
| microbiological features of kpc-producing enterobacter isolates identified in a u.s. hospital system. | microbiological data regarding klebsiella pneumoniae carbapenemase (kpc)-producing enterobacter spp. are scarce. in this study, 11 unique kpc-producing enterobacter isolates were identified among 44 ertapenem-nonsusceptible enterobacter isolates collected between 2009 and 2013 at a hospital system in western pennsylvania. all cases were healthcare-associated and occurred in medically complex patients. while pulsed-field gel electrophoresis showed diverse restriction patterns overall, multilocus ... | 2014 | 25053203 |
| resistance determinants and mobile genetic elements of an ndm-1-encoding klebsiella pneumoniae strain. | multidrug-resistant enterobacteriaceae are emerging as a serious infectious disease challenge. these strains can accumulate many antibiotic resistance genes though horizontal transfer of genetic elements, those for β-lactamases being of particular concern. some β-lactamases are active on a broad spectrum of β-lactams including the last-resort carbapenems. the gene for the broad-spectrum and carbapenem-active metallo-β-lactamase ndm-1 is rapidly spreading. we present the complete genome of klebsi ... | 2014 | 24905728 |
| clonal dissemination of oxa-370-producing klebsiella pneumoniae in rio de janeiro, brazil. | enzymes of the oxa-48 family have become some of the most important beta-lactamases in the world. a new oxa-48 variant (oxa-370) was first described for an enterobacter hormaechei strain isolated in rio grande do sul (southern region of brazil) in 2013. here we report detection of the blaoxa-370 gene in 24 isolates belonging to three enterobacteriaceae species (22 klebsiella pneumoniae isolates, 1 enterobacter cloacae isolate, and 1 enterobacter aerogenes isolate) collected from five hospitals i ... | 2015 | 25987619 |
| binding to histo-blood group antigen-expressing bacteria protects human norovirus from acute heat stress. | this study aims to investigate if histo-blood group antigen (hbga) expressing bacteria have any protective role on human norovirus (nov) from acute heat stress. eleven bacterial strains were included, belonging to escherichia coli, enterobacter cloacae, enterobacter aerogenes, clostridium difficile, bifidobacterium adolescentis, and b. longum. hbga expression of the bacteria as well as binding of human nov virus-like particles (vlps, gi.1, and gii.4 strains) to the bacteria were detected by flow ... | 2015 | 26191052 |
| enterobacter aerogenes and enterobacter cloacae; versatile bacterial pathogens confronting antibiotic treatment. | enterobacter aerogenes and e. cloacae have been reported as important opportunistic and multiresistant bacterial pathogens for humans during the last three decades in hospital wards. these gram-negative bacteria have been largely described during several outbreaks of hospital-acquired infections in europe and particularly in france. the dissemination of enterobacter sp. is associated with the presence of redundant regulatory cascades that efficiently control the membrane permeability ensuring th ... | 2015 | 26042091 |
| predominance of kpc-3 in a survey for carbapenemase-producing enterobacteriaceae in portugal. | among the 2,105 enterobacteriaceae tested in a survey done in portugal, 165 were nonsusceptible to carbapenems, from which 35 (26 klebsiella pneumoniae, 3 escherichia coli, 2 enterobacter aerogenes, and 3 enterobacter cloacae isolates and 1 klebsiella oxytoca isolate) were confirmed to be carbapenemase producers by the presence of 30 tn4401d-blakpc-3, 4 inti3-blages-5, and one inti1-blavim-2 gene, alone or in combination with other bla genes. the dissemination of blakpc-3 gene carried by an incf ... | 2015 | 25779587 |
| extended-spectrum-β-lactamase-producing enterobacteriaceae isolated from vegetables imported from the dominican republic, india, thailand, and vietnam. | to examine to what extent fresh vegetables imported into switzerland represent carriers of extended-spectrum-β-lactamase (esbl)-producing enterobacteriaceae, 169 samples of different types of fresh vegetables imported into switzerland from the dominican republic, india, thailand, and vietnam were analyzed. overall, 25.4% of the vegetable samples yielded one or more esbl-producing enterobacteriaceae, 78.3% of which were multidrug resistant. sixty isolates were obtained: escherichia coli, 26; kleb ... | 2015 | 25724954 |
| activity of eravacycline against enterobacteriaceae and acinetobacter baumannii, including multidrug-resistant isolates, from new york city. | eravacycline demonstrated in vitro activity against a contemporary collection of more than 4,000 gram-negative pathogens from new york city hospitals, with mic50/mic90 values, respectively, for escherichia coli of 0.12/0.5 μg/ml, klebsiella pneumoniae of 0.25/1 μg/ml, enterobacter aerogenes of 0.25/1 μg/ml, enterobacter cloacae 0.5/1 μg/ml, and acinetobacter baumannii of 0.5/1 μg/ml. activity was retained against multidrug-resistant isolates, including those expressing kpc and oxa carbapenemases ... | 2015 | 25534744 |
| separation and confirmation of nine enterobacteriaceae strains that carry the blandm-1 gene. | the aim of the present study was to confirm the existence of carbapenem-resistant enterobacteriaceae carrying the blandm-1 gene in clinics in hainan province, china. collected clinical bacterial isolates that were enterobacteriaceae strains suspected of producing carbapenemase were used as experimental strains. drug resistance to imipenem, meropenem and other antibacterial agents was tested. imipenem/imipenem inhibitor (ip/ipi) e-testing was conducted to identify the bacterial strains that produ ... | 2015 | 25780416 |
| carbapenem-resistant enterobacter spp. in retail seafood imported from southeast asia to canada. | | 2016 | 27533255 |
| antibacterial and antibiotic-resistance modifying activity of the extracts and compounds from nauclea pobeguinii against gram-negative multi-drug resistant phenotypes. | multi-drug resistance of gram-negative bacteria constitutes a major obstacle in the antibacterial fight worldwide. the discovery of new and effective antimicrobials and/or resistance modulators is necessary to combat the spread of resistance or to reverse the multi-drug resistance. in this study, we investigated the antibacterial and antibiotic-resistance modifying activities against 29 gram-negative bacteria including multi-drug resistant (mdr) phenotypes of the methanol extracts from nauclea p ... | 2016 | 27386848 |
| emergence of the plasmid-mediated mcr-1 gene in colistin-resistant enterobacter aerogenes and enterobacter cloacae. | | 2016 | 26976876 |
| risk factors for relapse or persistence of bacteraemia caused by enterobacter spp.: a case-control study. | enterobacter spp. possess chromosomal ampc beta-lactamases that may be expressed at high levels. previous studies have demonstrated a risk of relapsed bacteraemia following therapy with third generation cephalosporins (3gcs). what additional factors predict microbiological failure in enterobacter bacteraemia is unclear. we aimed to determine factors associated with microbiological failure in enterobacter bacteraemia. | 2017 | 28127422 |
| global assessment of the activity of tigecycline against multidrug-resistant gram-negative pathogens between 2004 and 2014 as part of the tigecycline evaluation and surveillance trial. | multidrug-resistant (mdr) gram-negative organisms are a burden on the global health care system. the tigecycline evaluation and surveillance trial (test) is an ongoing global study designed to monitor the in vitro activities of tigecycline and a panel of marketed antimicrobials against a range of clinically significant pathogens. in this study, in vitro data are presented for mdr acinetobacter baumannii, pseudomonas aeruginosa, escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, enterob ... | 2017 | 28124025 |
| production of 2,3-butanediol in saccharomyces cerevisiae by in silico aided metabolic engineering. | 2,3-butanediol is a chemical compound of increasing interest due to its wide applications. it can be synthesized via mixed acid fermentation of pathogenic bacteria such as enterobacter aerogenes and klebsiella oxytoca. the non-pathogenic saccharomyces cerevisiae possesses three different 2,3-butanediol biosynthetic pathways, but produces minute amount of 2,3-butanediol. hence, we attempted to engineer s. cerevisiae strain to enhance 2,3-butanediol production. | 2012 | 22640729 |
| complete genome sequence of enterobacter aerogenes kctc 2190. | this is the first complete genome sequence of the enterobacter aerogenes species. here we present the genome sequence of e. aerogenes kctc 2190, which contains 5,280,350 bp with a g + c content of 54.8 mol%, 4,912 protein-coding genes, and 109 structural rnas. | 2012 | 22493190 |
| alleviation of carbon catabolite repression in enterobacter aerogenes for efficient utilization of sugarcane molasses for 2,3-butanediol production. | due to its cost-effectiveness and rich sugar composition, sugarcane molasses is considered to be a promising carbon source for biorefinery. however, the sugar mixture in sugarcane molasses is not consumed as efficiently as glucose in microbial fermentation due to complex interactions among their utilizing pathways, such as carbon catabolite repression (ccr). in this study, 2,3-butanediol-producing enterobacter aerogenes was engineered to alleviate ccr and improve sugar utilization by modulating ... | 2015 | 26236395 |
| tss-emote, a refined protocol for a more complete and less biased global mapping of transcription start sites in bacterial pathogens. | bacteria rely on efficient gene regulatory mechanisms to switch between genetic programs when they are facing new environments. although this regulation can occur at many different levels, one of the key steps is the initiation of transcription. identification of the first nucleotide transcribed by the rna polymerase is therefore essential to understand the underlying regulatory processes, since this provides insight on promoter strength and binding sites for transcriptional regulators, and addi ... | 2016 | 27806702 |
| prevalence and antimicrobial resistance pattern of bacterial strains isolated from patients with urinary tract infection in messalata central hospital, libya. | to investigate the prevalence of urinary tract infection among patients at messalata central hospital, libya, to identify the causative bacteria, and to explore their resistance pattern to antimicrobials. | 2016 | 27569886 |
| antibacterial properties of tebipenem pivoxil tablet, a new oral carbapenem preparation against a variety of pathogenic bacteria in vitro and in vivo. | to systemically investigate the in vitro and in vivo antibacterial properties of tebipenem pivoxil tablet. in addition, acute toxicity of this preparation was also studied. | 2016 | 26751436 |
| repurposing salicylanilide anthelmintic drugs to combat drug resistant staphylococcus aureus. | staphylococcus aureus is a gram-positive bacterium that has become the leading cause of hospital acquired infections in the us. repurposing food and drug administration (fda) approved drugs for antimicrobial therapy involves lower risks and costs compared to de novo development of novel antimicrobial agents. in this study, we examined the antimicrobial properties of two commercially available anthelmintic drugs. the fda approved drug niclosamide and the veterinary drug oxyclozanide displayed str ... | 2015 | 25897961 |
| in vitro activity of ceftazidime, ceftaroline and aztreonam alone and in combination with avibactam against european gram-negative and gram-positive clinical isolates. | recent clinical isolates of key gram-negative and gram-positive bacteria were collected in 2012 from hospitalised patients in medical centres in four european countries (france, germany, italy and spain) and were tested using standard broth microdilution methodology to assess the impact of 4 mg/l avibactam on the in vitro activities of ceftazidime, ceftaroline and aztreonam. against enterobacteriaceae, addition of avibactam significantly enhanced the level of activity of these antimicrobials. mi ... | 2015 | 25748553 |
| spectral and biological evaluation of a synthetic antimicrobial peptide derived from 1-aminocyclohexane carboxylic acid. | ac-gf(a6c)g(a6c)k(a6c)g(a6c)f(a6c)g(a6c)gk(a6c)kkkk-amide (a6c=1-aminocyclohexane carboxylic acid) is a synthetic antimicrobial peptide (amp) that exhibits in vitro inhibitory activity against drug resistant strains of staphylococcus aureus, acinetobacter baumannii, klebsiella pneumoniae, pseudomonas aeruginosa, enterobacter aerogenes, and enterococcus faecium at concentrations ranging from 10.9 to 43μm. spectroscopic investigations were conducted to determine how this amp interacts with simple ... | 2015 | 25684423 |
| four carbapenem-resistant gram-negative species carrying distinct carbapenemases in a single patient. | carbapenem-resistant escherichia coli, klebsiella pneumoniae, enterobacter aerogenes, and acinetobacter baumannii were isolated from a single patient, each producing different carbapenemases (ndm-1, kpc-2, imp, and oxa-23, respectively). the ndm-1-producing e. coli strain was preceded by a clonally related carbapenem-susceptible strain a month earlier, suggesting in vivo acquisition of blandm-1. | 2015 | 25552359 |
| chemical composition and antibacterial activity of lavandula coronopifolia essential oil against antibiotic-resistant bacteria. | the aim of this study was to analyse the composition of the essential oil (eo) of lavandula coronopifolia from morocco and to evaluate its in vitro antibacterial activity against antibiotic-resistant bacteria isolated from clinical infections. the antimicrobial activity was assessed by a broth micro-well dilution method using multiresistant clinical isolates of 11 pathogenic bacteria: klebsiella pneumoniae subsp. pneumoniae, klebsiella ornithinolytica, escherichia coli, enterobacter cloacae, ent ... | 2015 | 25174508 |
| [the risk factors of ventilator-associated pneumonia in newborn and the changes of isolated pathogens]. | to study the risk factors of ventilator-associated pneumonia (vap) in newborn and the profiles of isolated pathogens. | 2013 | 24059113 |
| [investigation of the presence of new delhi metallo-beta-lactamase-1 (ndm-1) by pcr in carbapenem-resistant gram-negative isolates]. | bacteria producing new delhi metallo-beta-lactamase-1 (ndm-1) exhibit high level resistance to beta-lactams including carbapenems. this broad-spectrum resistance limits treatment options for infections caused by ndm-1 producers. ndm-1 was first isolated from an indian patient in sweden; since then, ndm-1 producing isolates have been identified in many countries including turkey. in this study, we investigated the presence of ndm-1 by pcr method in various gram-negative isolates recovered from cl ... | 2013 | 23621739 |
| bacterial community structure in treated sewage sludge with mesophilic and thermophilic anaerobic digestion. | stabilized sewage sludge is applied to agricultural fields and farmland due to its high organic matter content. the aim of this study was to investigate the effects of two types of sludge stabilization, mesophilic anaerobic digestion (mad) and thermophilic anaerobic digestion (tad), on bacterial communities in sludge, including the presence of pathogenic microorganisms. bacterial community structure and phylogenetic diversity were analyzed in four sewage sludge samples from the czech republic. a ... | 2015 | 25921720 |
| microbial diversity and dynamics during the production of may bryndza cheese. | diversity and dynamics of microbial cultures were studied during the production of may bryndza cheese, a traditional slovak cheese produced from unpasteurized ewes' milk. quantitative culture-based data were obtained for lactobacilli, lactococci, total mesophilic aerobic counts, coliforms, e. coli, staphylococci, coagulase-positive staphylococci, yeasts, fungi and geotrichum spp. in ewes' milk, curd produced from it and ripened for 0 - 10 days, and in bryndza cheese produced from the curd, in th ... | 2014 | 24291178 |
| antibacterial, antioxidant, antifungal and anti-inflammatory activities of crude extract from nitraria schoberi fruits. | this study is the first comprehensive investigation of the antibacterial, antioxidant, antifungal and anti-inflammatory activities of a crude extract from nitraria schoberi l. (zygophyllaceae) fruits. the extract was tested against four gram-negative (pseudomonas aeruginosa, enterobacter aerogenes, klebsiella pneumoniae and acinetobacter lwoffii) and one gram-positive (staphylococcus aureus) bacteria using the agar disc diffusion and microdilution methods. p. aeruginosa was inhibited the most (w ... | 2015 | 28324518 |
| antimicrobial, antitumor and brine shrimp lethality assay of ranunculus arvensis l. extracts. | to investigate the antitumor activity, brine shrimp lethality assay, antibacterial and antifungal activity of methanol extract (me), water extract (we), acetone extract (ae), chloroform extract (ce), methanol-water extract (mwe), methanol-acetone extract (mae), methanol-chloroform extract (mce) of ranunculus arvensis (l.). antitumor activity was evaluated with agrobacterium tumefaciens (at10) induced potato disc assay. cytotoxicity was evaluated with brine shrimp lethality assay. antibacterial a ... | 2015 | 26004705 |
| antimicrobial aflatoxins from the marine-derived fungus aspergillus flavus 092008. | a new aflatoxin, aflatoxin b(2b) (1), together with six known compounds, were isolated from the marine-derived fungus aspergillus flavus 092008 endogenous with the mangrove plant hibiscus tiliaceus (malvaceae). the structure of 1 was determined by the spectroscopic and chemical methods. compound 1 exhibited a moderate antimicrobial activity against escherichia coli, bacillus subtilis and enterobacter aerogenes, with mic values of 22.5, 1.7 and 1.1 m, respectively. compound 1 also showed a weak c ... | 2012 | 22941481 |
| evaluation of wound healing, anti-microbial and antioxidant potential of pongamia pinnata in wistar rats. | to investigate wound healing, antimicrobial and antioxidant activity of leaf extract of pongamia pinnata. | 2017 | 28053891 |
| antimicrobial assay and genetic screening of selected freshwater cyanobacteria and identification of a biomolecule dihydro-2h-pyran-2-one derivative. | explorations of freshwater cyanobacteria as antimicrobial (bacteria, fungi and methicillin-resistant staphylococcus aureus (mrsa) strains) drug resource using bioassay, nrps (non-ribosomal polypeptide synthetase) and pks (polyketide synthase) genes, as well as in silico approach. | 2017 | 28004519 |
| synthesis and antimicrobial evaluation of ester-linked 1,4-disubstituted 1,2,3-triazoles with a furyl/thienyl moiety. | twenty ester-linked 1,4-disubstituted 1,2,3-triazoles having a furyl/thienyl moiety have been synthesized from heteroaryl prop-2-yn-1-yl carboxylate and aromatic azides via a cu(i) catalyzed 1,3-dipolar cycloaddition. all the synthesized compounds were characterized by ftir, [formula: see text]h nmr, [formula: see text]c nmr spectroscopy and hrms. synthesized triazoles were tested in vitro for antimicrobial evaluation against gram-negative bacteria-escherichia coli, enterobacter aerogenes and kl ... | 2017 | 27900513 |
| antimicrobial properties of black grape (vitis vinifera l.) peel extracts against antibiotic-resistant pathogenic bacteria and toxin producing molds. | black grape peel possesses a substantial amount of polyphenolic antimicrobial compounds that can be used for controlling the growth of pathogenic microorganisms. the purpose of this study was to assess antibacterial and antifungal activity of black grape peel extracts against antibiotic-resistant pathogenic bacteria and toxin producing molds, respectively. | 2017 | 26729960 |
| physico-chemical analysis and antimicrobial potential of apis dorsata, apis mellifera and ziziphus jujube honey samples from pakistan. | to evaluate physico-chemical properties and antimicrobial potential of indigenous honey samples against different reference strains including escherichia coli atcc 8739, enterobacter aerogenes atcc 13048, pseudomonas aeroginosa atcc 9027, bacillus subtilis atcc 6633, staphylococcus aureus atcc 25923, salmonella typhi atcc 14028, klebsiella pneumonia atcc 13883, aspergillus niger atcc 16404, rhizopus oligosporus pcsir1, candida albicans atcc 14053 and candida utilis atcc 9950. | 2014 | 25183333 |
| in vivo antioxidative property, antimicrobial and wound healing activity of flower extracts of pyrostegia venusta (ker gawl) miers. | pyrostegia venusta (ker gawl) miers. (bignoniaceae), has been traditionally used as a remedy for treating white patches and infections on the skin (leukoderma, vitiligo). | 2012 | 22265749 |
| identification of enterobacteriaceae by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using the vitek ms system. | this multicenter study evaluated the accuracy of matrix-assisted laser desorption/ionization time-of-flight (maldi-tof) mass spectrometry identifications from the vitek ms system (biomérieux, marcy l'etoile, france) for enterobacteriaceae typically encountered in the clinical laboratory. enterobacteriaceae isolates (n = 965) representing 17 genera and 40 species were analyzed on the vitek ms system (database v2.0), in accordance with the manufacturer's instructions. colony growth (≤72 h) was app ... | 2013 | 23818163 |
| inactivation of bacteria and yeast using high-frequency ultrasound treatment. | high-frequency (850 khz) ultrasound was used to inactivate bacteria and yeast at different growth phases under controlled temperature conditions. three species of bacteria, enterobacter aerogenes, bacillus subtilis and staphylococcus epidermidis as well as a yeast, aureobasidium pullulans were considered. the study shows that high-frequency ultrasound is highly efficient in inactivating the bacteria in both their exponential and stationary growth phases, and inactivation rates of more than 99% w ... | 2014 | 24835956 |
| inactivation of microorganisms by low-frequency high-power ultrasound: 2. a simple model for the inactivation mechanism. | a simple theoretical model based on shear forces generated by the collapse of the ultrasound cavities near the surface of a microorganism is proposed. this model requires two parameters which take into account the number of acoustic cavitation bubbles, and the resistance of the cell wall of the microorganism to the shear forces generated by bubble collapse. to validate the model, high-power low frequency (20 khz) ultrasound was used to inactivate two microorganisms with very different sizes, viz ... | 2014 | 23845410 |
| safety, efficacy and utility of methods of transferring adhesive and cohesive escherichia coli cells to microplates to avoid aerosols. | the virtual colony count (vcc) microbiological assay has been utilized for over a decade to measure the antimicrobial activity of peptides such as defensins and ll-37 against biosafety level (bsl)-1 and bsl-2 bacteria including escherichia coli, staphylococcus aureus, bacillus cereus, and enterobacter aerogenes. in addition, a modified pipetting technique was presented in a 2011 study of defensin activity against the bsl-3 pathogen bacillus anthracis. both studies were published in the journal ... | 2014 | 25671086 |
| composition, in vitro cytotoxic, and antimicrobial activities of the flower essential oil of diospyros discolor from taiwan. | this study investigated the chemical composition, in vitro cytotoxic, and antimicrobial activities of the essential oil isolated from the flower of diospyros discolor from taiwan. the essential oil was isolated using hydrodistillation in a clevenger-type apparatus, and characterized by gc-fid and gc-ms. twenty-eight compounds were identified, representing 100% of the oil. the main components identified were (2z,6e)-farnesol (35.0%), α-cadinol (10.9%), (e)-nerolidol (6.9%), α-humulene (6.0%), τ-c ... | 2015 | 26411038 |
| synthesis of novel sulfonamide analogs containing sulfamerazine/sulfaguanidine and their biological activities. | sulfamerazine and sulfaguanidine are clenched with p-nitrobenzoyl chloride and the products obtained are reduced to naxs in ethanol-water. novel sulfonamides (6a-g and 9a-g) were synthesized by the reaction of these reduced products (4 and 8) with various sulfonyl chlorides (5a-g). the structures of these compounds were characterized using spectroscopic analysis (ir, (1)h-nmr, (13)c-nmr and hrms) technique. antimicrobial activity of sulfonamides (3, 4, 7, 8, 6a-g and 9a-g) was evaluated by the a ... | 2016 | 26327456 |
| antimicrobial and cytotoxic activities from jatropha dioica roots. | the antimicrobial and cytotoxic activities of organic extracts obtained from roots of the medicinal plant jatropha dioica (euphorbiaceae) were investigated. in order to evaluate their antimicrobial activity, the organic extracts were tested against clinical isolates of the human pathogens bacillus cereus, escherichia coli, salmonella typhi, staphylococcus aureus, enterobacter aerogenes, enterobacter cloacae, salmonella typhimurium, cryptococcus neoformans, candida albicans, candida parapsilosis ... | 2014 | 26031013 |
| pyrosequencing analysis of microbial community and food-borne bacteria on restaurant cutting boards collected in seri kembangan, malaysia, and their correlation with grades of food premises. | this study adopts the pyrosequencing technique to identify bacteria present on 26 kitchen cutting boards collected from different grades of food premises around seri kembangan, a city in malaysia. pyrosequencing generated 452,401 of total reads of otus with an average of 1.4×10(7) bacterial cells/cm(2). proteobacteria, firmicutes and bacteroides were identified as the most abundant phyla in the samples. taxonomic richness was generally high with >1000 operational taxonomic units (otus) observed ... | 2015 | 25679309 |
| effect of white mustard essential oil on the growth of foodborne pathogens and spoilage microorganisms and the effect of food components on its efficacy. | antimicrobial preservative compounds are added to foods to target specific pathogens and spoilage organisms. white mustard essential oil (wmeo) is an extract that contains 4-hydroxybenzyl isothiocyanate, a compound which has been demonstrated to have antimicrobial activity in limited studies. the objective of this research was to determine the in vitro antimicrobial activity of wmeo against gram-positive and gram-negative spoilage and pathogenic bacteria and determine the effect of food componen ... | 2014 | 25474051 |
| microwave-assisted synthesis of diverse pyrrolo[3,4-c]quinoline-1,3-diones and their antibacterial activities. | with the aim of developing a general and practical method for library production, a novel and efficient two-phase microwave-assisted cascade reaction between isatins and β-ketoamides in [bmim]bf4/toluene was developed for the synthesis of pyrrolo[3,4-c]quinoline-1,3-diones. the features of this methodology are, the use of microwave-assisted rapid synthesis, mild reaction conditions, high yields, operational simplicity, facile product separation, and recyclability. furthermore, the antibacterial ... | 2014 | 24749663 |
| efficacy of commercial natural antimicrobials alone and in combinations against pathogenic and spoilage microorganisms. | microbial control strategies are needed in the food industry to prevent foodborne illnesses and outbreaks and prolong product shelf life. the aim of this study was to investigate and compare the efficacy of the commercial natural antimicrobials white mustard essential oil (wmeo), citrus flavonoid and acid blend (cfab), olive extract (oe), nisaplin (a compound containing nisin), and lauric arginate (lae) alone and in combinations against foodborne pathogens and spoilage microorganisms. mics of in ... | 2014 | 24490921 |
| antimicrobial activity of schinus lentiscifolius (anacardiaceae). | schinus lentiscifolius marchand (syn. schinus weinmannifolius engl) is a plant native to rio grande do sul (southern brazil) and has been used in brazilian traditional medicine as antiseptic and antimicrobial for the treatment of many different health problems as well as to treat leucorrhea and to assist in ulcer and wound healing. although it is a plant widely used by the population, there are no studies proving this popular use. | 2013 | 23684720 |
| synthesis and characterization of a series of transition metal complexes with a new symmetrical polyoxaaza macroacyclic schiff base ligand: x-ray crystal structure of cobalt(ii) and nickel(ii) complexes and their antibacterial properties. | a new symmetrical [n4o2] hexadentate schiff base ligand, (e)-n-(pyridin-2-ylmethylene)-2-(3-(2-((e)-pyridin-2-lmethyleneamino)phenoxy)naphthalen-2-yloxy)benzenamine, abbreviated to l, and its complexes of ni(ii), cu(ii), zn(ii), co(ii), cd(ii) and mn(ii) have been synthesized in the presence of metal ions. the complexes were structurally characterized by elemental analyses, ir, uv-vis, nmr and molar conductivity. the crystal structures of two complexes, [nil(ono2)2]·2h2o and [colcl2]ch3oh·0.5h2o ... | 2013 | 23099161 |
| postprocessing microflora of commercial attieke (a fermented cassava product) produced in the south of côte d'ivoire. | the distribution and presence of hygiene indicator and pathogenic micro-organisms in 375 samples of attieke marketed in côte d'ivoire, and their roles in the food poisoning were evaluated. microbiological analyses were carried out, which included the total viable bacteria, coliforms, escherichia coli, staphylococcus aureus, salmonella, bacillus spores, fungi and clostridium perfringens. the results revealed that the viable bacteria counts ranged from 2·2 ± 1·2 × 10(5) to 3·4 ± 1·4 × 10(6) cfu g( ... | 2013 | 23078634 |
| phyto-synthesis of silver nanoscale particles using morinda citrifolia l. and its inhibitory activity against human pathogens. | leaf extract of morinda citrifolia l. was assessed for the synthesis of silver nanoscale particles under different temperature and reaction time. synthesized nanoscale (mcagnps) particles were confirmed by analysing the excitation of surface plasmon resonance (spr) using uv-visible spectrophotometer at 420 nm. further sem, hrtem analysis confirmed the range of particle size between 10 and 60 nm and sead pattern authorizes the face centered cubic (fcc) crystalline nature of the mcagnps. fourier t ... | 2012 | 22483838 |
| isolation, partial purification and evaluation of bioactive compounds from leaves of ageratum houstonianum. | the present study deals with the isolation and partial purification of bioactive compounds from the crude methanol extracts of the leaves of ageratum houstonianum (asteraceae). the quantification and the identification of compounds in the crude extract and active bands isolated by preparative tlc were accomplished using gc-ms analysis. the most important compounds identified in the crude extract and active bands (ab-1 and ab-2) were 6-acetyl-7-methoxy-2, 2-dimethylchromene, hexadecanoic acid and ... | 2012 | 27350770 |
| synthesis, sar and antibacterial activity of hybrid chloro, dichloro-phenylthiazolyl-s-triazines. | a series of hybrid novel chloro (1a-9a) and dichloro (10b-18b) phenylthiazolyl-s-triazine were synthesized and subsequently subjected to their antibacterial activity against three gram positive viz. lactobacillus casei (ncim-2651); bacillus cereus (ncim-2458); staphylococcus aureus (ncim-2120) and three gram negative viz salmonella typhimurium (ncim-2501); escherichia coli (ncim-2065); klebsiella aerogenes (ncim-2098). the sar studies around the lead compound revealed that introduction of electr ... | 2012 | 23960775 |
| complex microbiota of a chinese "fen" liquor fermentation starter (fen-daqu), revealed by culture-dependent and culture-independent methods. | daqu is a traditional fermentation starter that is used for chinese liquor production. although partly mechanized, its manufacturing process has remained traditional. we investigated the microbial diversity of fen-daqu, a starter for light-flavour liquor, using combined culture-dependent and culture-independent approaches (pcr-dgge). a total of 190 microbial strains, comprising 109 bacteria and 81 yeasts and moulds, were isolated and identified on the basis of the sequences of their 16s rdna (ba ... | 2012 | 22608236 |
| essential oil variation in the populations of artemisia spicigera from northwest of iran: chemical composition and antibacterial activity. | artemisia spicigera c. koch (asteraceae) is a perennial shrubby herb and is generally distributed in armenia, iran, and middle anatolia. this species traditionally has been used in medicines. | 2013 | 23126238 |
| broadly reactive aptamers targeting bacteria belonging to different genera using a sequential toggle cell-selex. | conventional cell-selex aims to isolate aptamers to a single unique target bacteria species. we propose a method to isolate single-stranded dna aptamers that have broad reactivity to multiple bacterial targets belonging to different genera. the key of the proposed method is that targets of interest are changed sequentially at each selex round. the general scheme was examined using six bacteria from different genera, escherichia coli, enterobacter aerogenes, klebsiella pneumoniae, citrobacter fre ... | 2017 | 28272554 |
| biosynthesis characterization of silver nanoparticles using cassia roxburghii dc. aqueous extract, and coated on cotton cloth for effective antibacterial activity. | the present study reports the green synthesis of silver nanoparticles (agnps) from silver precursor using a plant biomaterial, cassia roxburghii dc., aqueous extract. the agnps were synthesized from the shade-dried leaf extract and assessed for their stability; they elucidated characteristics under uv-visible spectroscopy, x-ray diffraction, fourier transform infrared spectroscopy, high-resolution transmission electron microscopy, and energy dispersive x-ray spectroscopy. the synthesized agnps e ... | 2015 | 26491310 |
| effect of nanocomposite packaging containing zno on growth of bacillus subtilis and enterobacter aerogenes. | recent advances in nanotechnology have opened new windows in active food packaging. nano-sized zno is an inexpensive material with potential antimicrobial properties. the aim of the present study is to evaluate the antibacterial effect of low density polyethylene (ldpe) containing zno nanoparticles on bacillus subtilis and enterobacter aerogenes. zno nanoparticles have been synthesized by facil molten salt method and have been characterized by x-ray diffraction (xrd), and scanning electron micro ... | 2016 | 26478403 |
| biological activities of morus celtidifolia leaf extracts. | the aims of this research were to examine the antibacterial, cytotoxic and antiradical/antioxidant activities of the organic extracts obtained from the leaves of the medicinal plant morus celtidifolia (family: moraceae). to evaluate its antimicrobial properties, m. celtidifolia was tested against the bacteria of medical importance: bacillus subtilis, staphyloccocus aureus, enterococcus faecalis, escherichia coli, enterobacter cloacae and enterobacter aerogenes. cytotoxic activity was assessed by ... | 2015 | 26142508 |
| probiotic potential of lactobacillus strains isolated from sorghum-based traditional fermented food. | sorghum-based traditional fermented food was screened for potential probiotic lactic acid bacteria. the isolates were identified by biochemical, physiological and genetic methods. species identification was done by 16s rrna sequence analysis. the functional probiotic potential of the two lactobacillus species viz., lactobacillus plantarum (lact. plantarum) and lactobacillus pentosus (lact. pentosus) was assessed by different standard parameters. the strains were tolerant to ph 2 for 1 h and resi ... | 2015 | 25666113 |
| purification of a secreted lectin from andrias davidianus skin and its antibacterial activity. | a lectin secreted from andrias davidianus skin (adl) was purified by affinity chromatography on porcine stomach mucin (type iii) (psm)-crosslinked albumin, followed by gel filtration on sephadex g-100 and hplc on tsk gel g3000pwxl. the purified lectin was found to be a dimeric protein, as revealed by sds-page and maldi-tof analysis. sds-page showed that the adl protein had a molecular mass of 17 kda. adl produced an 8.5 kda band when examined using sds-page under reducing conditions. adl aggluti ... | 2015 | 25445018 |
| fabrication of swcnt-ag nanoparticle hybrid included self-assemblies for antibacterial applications. | the present article reports the development of soft nanohybrids comprising of single walled carbon nanotube (swcnt) included silver nanoparticles (agnps) having superior antibacterial property. in this regard aqueous dispersing agent of carbon nanotube (cnt) containing a silver ion reducing unit was synthesised by the inclusion of tryptophan and tyrosine within the backbone of the amphiphile. the dispersions were characterized spectroscopically and microscopically using tem, afm and raman spectr ... | 2014 | 25191756 |
| inactivation of microorganisms by low-frequency high-power ultrasound: 1. effect of growth phase and capsule properties of the bacteria. | the aim of this study was to determine the effects of high-intensity low-frequency (20 khz) ultrasound treatment on the viability of bacteria suspension. more specifically, we have investigated the relationship between the deactivation efficiency and the physical (size, hydrophobicity) and biological (gram-status, growth phase) properties of the microbes. enterobacter aerogenes, bacillus subtilis, staphylococcus epidermidis, s. epidermidis sk and staphylococcus pseudintermedius were chosen for t ... | 2014 | 23835398 |
| microbiology of controlled rotting of egusi (colocynthis citrullus l.) fruits for the harvesting of the seeds. | microorganisms isolated from naturally rotting egusi fruits which are used as a source of dietary seeds, were mainly bacteria: bacillus subtilis, b. licheniformis, b. polymyxa, b. megaterium, b. pumilus, lactobacillus plantarum, la. brevis, leuconostoc mesenteroides, enterobacter aerogenes, e. cloacae, klebsiella aerogenes, k. pneumoniae, staphylococcus epidermidis, s. aureus, micrococcus and candida spp. the rotting period of egusi fruits could be decreased from 120 to 72 h by using a mixture o ... | 1994 | 24421184 |
| toxicity of chlortetracycline and its metal complexes to model microorganisms in wastewater sludge. | complexation of antibiotics with metals is a well-known phenomenon. wastewater treatment plants contain metals and antibiotics, thus it is essential to know the effect of these complexes on toxicity towards microorganisms, typically present in secondary treatment processes. in this study, stability constants and toxicity of chlortetracycline (ctc) and metal (ca, mg, cu and cr) complexes were investigated. the calculated stability constants of ctc-metal complexes followed the order: mg-ctc>ca-ctc ... | 2015 | 26119381 |
| intraoperative vancomycin use in spinal surgery: single institution experience and microbial trends. | retrospective case series. | 2014 | 24480966 |
| isolation, development and identification of salt-tolerant bacterial consortium from crude-oil-contaminated soil for degradation of di-azo dye reactive blue 220. | the objective of this study was development and characterization of a halophilic bacterial consortium for rapid decolorization and degradation of a wide range of dyes and their mixtures. the 16s rrna gene analysis of developed halophilic consortium vn.1 showed that the bacterial consortium contained six bacterial strains, which were identified as pseudomonas fluorescens hm480360, enterobacter aerogenes hm480361, shewanella sp. hm589853, arthrobacter nicotianae hm480363, bacillus beijingensis hm4 ... | 2015 | 26177415 |
| wound healing activity and mechanisms of action of an antibacterial protein from the venom of the eastern diamondback rattlesnake (crotalus adamanteus). | basic phospholipase a2 was identified from the venom of the eastern diamondback rattlesnake. the crotalus adamanteus toxin-ii (catx-ii) induced bactericidal effects (7.8 µg/ml) on staphylococcus aureus, while on burkholderia pseudomallei (khw), and enterobacter aerogenes were killed at 15.6 µg/ml. catx-ii caused pore formation and membrane damaging effects on the bacterial cell wall. catx-ii was not cytotoxic on lung (mrc-5), skin fibroblast (hepk) cells and in mice. catx-ii-treated mice showed ... | 2014 | 24551028 |
| one-pot synthesis and antimicrobial evaluation of novel 3-cyanopyridine derivatives of (-)-β-pinene. | a series of novel 3-cyanopyridine derivatives of (-)-β-pinene were designed and synthesized by one-pot four-component domino reactions. the targeted compounds were evaluated for their antimicrobial activity against four bacteria (klebsiella pneumoniae, enterobacter aerogenes, staphylococcus aureus, staphylococcus epidermidis) and a fungus (candida albicans). the results showed that most of the minimal inhibitory concentrations (mics) of these 3-cyanopyridine derivatives against the tested strain ... | 2016 | 26898336 |
| antibacterial and antimycotic activity of cotton fabrics, impregnated with silver and binary silver/copper nanoparticles. | effective method of obtaining of the bactericidal bandage materials by impregnation of cotton fabric by aqueous solutions of silver and copper salts followed by a certain regime of heat treatment is developed. the study of obtained materials by methods of optical spectroscopy, electron microscopy, and x-ray phase analysis showed the formation of crystalline silver nanoparticles (nps) and bimetallic ag/cu composites with the corresponding surface plasmon resonance (spr) bands in the absorption sp ... | 2016 | 26781286 |