| symptomatic ascites in a patient with hypothyroidism of short duration. | symptomatic ascites as a presenting symptom of hypothyroidism is quite rare. in most of the case reports, patients with ascites requiring therapeutic abdominal paracentesis have long-standing hypothyroidism. we present a case of symptomatic ascites in a subject with hypothyroidism following radioiodine therapy for graves disease. a 70-year-old african-american man presented with increasing weakness, shortness of breath, weight gain, constipation, and abdominal distention. past history was signif ... | 2007 | 17220693 |
| [the effect of propylthiouracil on the efficacy of radioiodine (i-131) therapy in graves hyperthyroidism]. | aiming at evaluating the effect of antithyroid drugs on the efficacy of radioiodine treatment (rai) we retrospectively analyzed 226 patients with graves disease hyperthyroidism submitted to rai between 1990 and 2001: 58 patients without any antithyroid drug (atd) prior to rai, 119 patients using propylthiouracil (ptu) and 49 patients using methimazole (mmi) prior to rai. clinical and laboratory parameters 1 year after rai defined their clinical status (cured or not cured). high serum free t4 and ... | 2006 | 17221116 |
| mitochondrial dna variants in bulgarian patients affected by multiple sclerosis. | the occurrence of multiple sclerosis (ms) in subjects clustering to a particular mitochondrial dna (mtdna) haplogroup/haplotype or carrying mtdna mutations associated with leber's hereditary optic neuropathy (lhon) has suggested that mitochondrial genome may contribute to susceptibility to ms. in the present study, 58 unrelated bulgarian patients with relapsing remitting form of ms and 104 randomly selected healthy individuals were analysed for the presence of 14 mtdna polymorphisms determining ... | 2007 | 17222112 |
| t3 replacement does not prevent excitotoxic cell death but reduces developmental neuronal apoptosis in newborn mice. | periventricular leukomalacia (pvl) is a major cause of neurological handicap in pre-term infants. at present, there are no effective or causal therapies available. thyroid hormones play an essential role in brain development and are reported to be decreased in pre-terms and following brain injury in adults. | 2007 | 17222575 |
| molecular identification of free-living amoebae of the vahlkampfiidae and acanthamoebidae isolated in arizona (usa). | sediment samples from rivers, canals and lakes in arizona (usa) were cultured for free-living amoebae at three different incubation temperatures (22, 37 and 40 degrees c). isolates belonging to the vahlkampfiidae were identified by sequencing the pcr-amplified its1, 5.8s and its2 rdna. with this molecular method three naegleria spp. were identified, n. gruberi sensu stricto, n. australiensis and n. tihangensis. also a strain each of willaertia magna and vahlkampfia avara were identified. three s ... | 2007 | 17222746 |
| disrupting effects of hydroxy-polychlorinated biphenyl (pcb) congeners on neuronal development of cerebellar purkinje cells: a possible causal factor for developmental brain disorders? | polychlorinated biphenyls (pcbs) and hydroxy-pcb (oh-pcb) metabolites are widely distributed bioaccumulative environmental chemicals and have similar chemical structures to those of thyroid hormones (ths). previously, we reported that ths are essential for neuronal development and the low doses of two oh-pcbs, namely, 4-oh-2',3,3',4',5'-pentachlorobiphenyl (4'-oh-pecb-106) and 4-oh-2',3,3',4',5,5'-hexachlorobiphenyl (4'-oh-hxcb-159), inhibited the th-dependent dendritic development of purkinje c ... | 2007 | 17223178 |
| skeletal changes after modified intraoral vertical ramus osteotomy for correction of mandibular prognathism. | orthognathic surgery is widely used to correct congenital and acquired dentofacial discrepancies. various surgical procedures have been advocated for correction of mandibular prognathism. in this study, a modified intraoral vertical ramus osteotomy has been developed for surgical correction of mandibular prognathism. the aim of this study is to identify contributing factors to skeletal change by analysing cephalometric changes after modified intraoral vertical ramus osteotomy. | 2007 | 17223511 |
| [msct for staging and response evaluation of esophageal cancer]. | squamous cell carcinomas and adenocarcinomas account for the majority of cases of esophageal cancer. esophageal cancer often is diagnosed in advanced stages as clinical symptoms are lacking in early stages. the major aims of imaging in esophageal cancer are to determine local tumor extension (t and n staging), to rule out systemic disease (m staging), and to assess response to neoadjuvant therapy (response evaluation). ct is still inferior to endoscopic ultrasound in differentiating t stages and ... | 2007 | 17225186 |
| [effects of remifentanil in children undergoing endoscopic-assisted adenoidectomy]. | to observe the effect of remifentanil on hemodynamic and angiotentratin- ii in children undergoing endoscopic-assisted adenoidectomy. | 2006 | 17225518 |
| detection of disseminated pancreatic cells by amplification of cytokeratin-19 with quantitative rt-pcr in blood, bone marrow and peritoneal lavage of pancreatic carcinoma patients. | to evaluate the diagnostic potential of cytokeratin-19 (ck-19) mrna for the detection of disseminated tumor cells in blood, bone marrow and peritoneal lavage in patients with ductal adenocarcinoma of the pancreas. | 2007 | 17226905 |
| encapsulated magnetic nanoparticles as supports for proteins and recyclable biocatalysts. | this paper describes the bioconjugation of histidine-tagged enzymes and other proteins to the surface of composite "magnetomicelles" consisting of magnetic gamma-fe2o3 nanoparticles encapsulated within cross-linked polystyrene-block-polyacrylate copolymer micelle shells. free carboxylic acid groups on the magnetomicelle surface were converted to cu2+-iminodiacetic acid (ida) for protein capture. the conjugation of t4 dna ligase and enhanced green fluorescent protein to magnetomicelles revealed t ... | 2007 | 17226972 |
| concurrent chemoradiation for patients with squamous cell carcinoma of the cervical esophagus. | little is known concerning the role of concurrent chemoradiation (ccrt) in the management of carcinoma of the cervical esophagus. we retrospectively evaluated our treatment approach for patients with cervical esophageal cancer with special emphasis on ccrt with or without surgery. medical records of 21 consecutive patients with cervical esophageal carcinoma treated mainly with ccrt (1997-2004) were reviewed, and factors that influenced patient survival were analyzed retrospectively. nineteen rec ... | 2007 | 17227304 |
| [cloning human heat shock protein 90beta-cdna and constructing its eukaryon vector]. | the purpose of this study was to clone human hsp90beta cdna and construct its eukaryote expression vector . the total rna was isolated by trizol reagent (invitrogen) from human npc and its cdna was gained by rt-pcr. the purified rt-pcr products and pgem-t easy vector were ligated and transformed into xl1-blue e. coli bacteria. the white clones were selected and the plasmid was purified, which was further identified by double enzyme digestion and sequenced. pgem-hhsp90beta and pcdna3.1(+) dna wer ... | 2006 | 17228728 |
| surgical management of lung cancer invading the aorta or the superior vena cava. | invasion of mediastinal structures (t4) is considered as an absolute contraindication to surgical management of non-small cell lung cancer (nsclc). the authors studied the role of surgical treatment in case of direct aortic and superior venous caval involvement. | 2007 | 17229487 |
| [case of acute hepatitis associated with basedow's disease]. | a 20-year-old woman given a diagnosis of hyperthyroidism (basedow's disease) had been subsequently treated with methimazole since 1999. as she could not be made euthyroid, surgery was planned to relieve the symptoms. because of liver dysfunction after discontinuation of methimazole and administration of iodine, she was admitted to the hospital. she was negative for hepatitis a, b and c virus serologies, but positive for anti-nuclear antibodies. a liver biopsy, which showed features of chronic ac ... | 2007 | 17230007 |
| myocardial infarction masked by high level spinal anesthesia in a patient undergoing herniorrhaphy. | myocardial infarction (mi) is one of the leading causes of perioperative morbidity. although evidence to prove significant reduction of perioperative mi with regional anesthesia is lacking, anesthesiologists still prefer this technique over general anesthesia for surgery involving the lower abdomen or lower extremities, especially in patients with cardiac risks. however, high level of sensory block during spinal anesthesia may obscure the referred pain from mi, which could contribute to the dela ... | 2006 | 17233370 |
| effects of bone marrow cell transplant on thyroid function in an i131-induced low t4 and elevated tsh rat model. | we developed a study using low dose radioactive iodine creating an animal model of transient elevation of thyroid stimulating hormone (tsh). male derived bone marrow cells were transplanted to asses their effect on thyroid function and their capability to repair the thyroid parenchyma. | 2007 | 17233913 |
| patterns of nodal relapse after surgery and postoperative radiation therapy for carcinomas of the major and minor salivary glands: what is the role of elective neck irradiation? | to evaluate the incidence of nodal relapses from carcinomas of the salivary glands among patients with clinically negative necks in an attempt to determine the potential utility of elective neck irradiation (eni). | 2007 | 17234357 |
| hydrolytic cleavage of dna by quercetin manganese(ii) complexes. | quercetin manganese(ii) complexes were investigated focusing on its dna hydrolytic activity. the complexes successfully promote the cleavage of plasmid dna, producing single and double dna strand breaks. the amount of conversion of supercoiled form (sc) of plasmid dna to the nicked circular form (nc) depends on the concentration of the complex as well as the duration of incubation of the complexes with dna. the maximum rate of conversion of the supercoiled form to the nicked circular form at ph ... | 2007 | 17234390 |
| p38-mapk induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and atpase activity. | our objective in work presented here was to understand the mechanisms by which activated p38alpha mapk depresses myocardial contractility. to test the hypothesis that activation of p38 mapk directly influences sarcomeric function, we used transgenic mouse models with hearts in which p38 mapk was constitutively turned on by an upstream activator (mkk6be). these hearts demonstrated a significant depression in ejection fraction after induction of the transgene. we also studied hearts of mice expres ... | 2007 | 17234967 |
| induction chemoradiation and surgical resection for superior sulcus non-small-cell lung carcinomas: long-term results of southwest oncology group trial 9416 (intergroup trial 0160). | traditional treatment for superior sulcus non-small-cell lung cancers (ss nsclc), radiation plus surgery, yields a 50% rate of complete resection and a 30% 5-year survival. on the basis of improved outcomes in other subsets of stage iii nsclc, this trial tested the feasibility of induction chemoradiotherapy for ss nsclc. | 2007 | 17235046 |
| mortality and causes of death after multimodality treatment for advanced oral and oropharyngeal cancer. | to analyze mortality and causes of death in patients who received preoperative radiochemotherapy and underwent radical surgery for advanced oral or oropharyngeal cancer. | 2007 | 17236930 |
| functinal and aesthetic outcome of reconstruction of large oro-facial defects involving the lip after tumor resection. | squamous cell carcinoma of the head and neck is a challenging disease to both surgeons and radiation oncologists due to proximity of many important anatomical structures. surgery could be curative as these cancers usually metastasize very late by blood stream. | 2006 | 17237851 |
| characterization of a homologous-region-binding protein from white spot syndrome virus by phage display. | homologous regions (hrs) of white spot syndrome virus (wssv) might serve as origins of dna replication or be involved in transcriptional regulation. to characterize the interaction between hrs of wssv and the viral proteins, in this investigation, phage display technology was used. wssv genomic dna was sheared by sonication to generate fragments in lengths between 0.5 and 2.0 kb. then these fragments were blunt-ended with t4 dna polymerase and cloned into the ecorv site of rebuilt vector pcantab ... | 2007 | 17240469 |
| influence of controlled hypotension using esmolol and sodium nitroprusside on natriuretic peptides in patients undergoing endonasal sinus surgery. | atrial and brain natriuretic peptide, synthesized by cardiac myocytes, are mediators secreted secondary to cardiac volume expansion and increased filling pressure. the study was designed to assess serum concentration of atrial and brain natriuretic peptide in patients undergoing endonasal sinus surgery receiving controlled hypotension. | 2007 | 17241506 |
| local-regional recurrence after surgery without postoperative irradiation for carcinomas of the major salivary glands: implications for adjuvant therapy. | to determine factors predictive of local-regional recurrence (lrr) after surgery alone for carcinomas of the major salivary glands in an attempt to evaluate the potential role of postoperative radiation therapy. | 2007 | 17241753 |
| axillary hyperhidrosis: t3/t4 versus t4 thoracic sympathectomy in a series of 276 cases. | different techniques of video-assisted thoracic sympathectomy have been suggested to control the symptoms of axillary hyperhidrosis. we compared the results using two different levels of ganglion resection for treating axillary hyperhidrosis: t3/t4 vs. t4. | 2006 | 17243877 |
| attenuation of oxidative stress in plasma and tissues of rats with experimentally induced hyperthyroidism by caffeic acid phenylethyl ester. | increased oxidative stress with high free radical generation has been described previously in animal models of hyperthyroidism. the present study was designed to investigate the protective effects of caffeic acid phenylethyl ester (cape) on oxidative damage in rats with experimentally induced hyperthyroidism. the study was conducted on 32 male sprague-dawley rats. the experimental animals were divided into four groups (control, cape alone, hyperthyroidism, and hyperthyroidism + cape). hyperthyro ... | 2007 | 17244256 |
| thyroglobulin gene mutations producing defective intracellular transport of thyroglobulin are associated with increased thyroidal type 2 iodothyronine deiodinase activity. | most patients with defective synthesis and/or secretion of thyroglobulin (tg) present relatively high serum free t3 (ft3) concentrations with disproportionately low free t4 (ft4) resulting in a high ft3/ft4 ratio. the mechanism of this change in ft3/ft4 ratio remains unknown. | 2007 | 17244789 |
| sentinel lymph node biopsy is feasible for breast cancer patients after neoadjuvant chemotherapy. | despite the increasing use of both sentinel lymph node (sln) biopsy and neoadjuvant chemotherapy (nac) in patients with operable breast cancer, information on the feasibility and accuracy of sentinel node biopsy following neoadjuvant chemotherapy is still quite limited. therefore, we investigated the feasibility and accuracy of sentinel lymph node biopsy for breast cancer patients after nac. | 2007 | 17244988 |
| enhanced prediction of fracture risk combining vertebral fracture status and bmd. | prevalent vertebral fractures are associated with increased fracture risk, but the magnitude of this effect across a range of bmd t-scores has not been quantified. in this analysis, for any given bmd t-score, incident fracture risk varied up to twelve fold when information regarding prevalent radiographic vertebral fracture status was considered. | 2007 | 17245546 |
| genetic structure of bacteriophage t4 as described by recombination studies of factors influencing plaque morphology. | | 1953 | 17247424 |
| phenotypic properties of heterozygotes in the bacteriophage t4. | | 1958 | 17247753 |
| high negative interference over short segments of the genetic structure of bacteriophage t4. | | 1958 | 17247760 |
| linkage of genetic markers in phages t2 and t4. | | 1960 | 17247999 |
| marker stimulation of crossing over: a test of the theory yielding negative results and using rii mutants of phage t4. | | 1965 | 17248241 |
| induction of pure mutant clones by repair of inactivating dna alterations in phage t4. | | 1966 | 17248334 |
| increased incidence of congenital hypothyroidism due to iodine deficiency. | the incidence of congenital hypothyroidism (ch) is expected to be elevated in iodine-deficient areas. in this study, the authors aimed to determine the incidence of transient and permanent ch in a large city which is known to be in the zone of moderate iodine deficiency. | 2007 | 17250510 |
| neuromuscular effects of sevoflurane in myasthenia gravis patients. | little information is available regarding the neuromuscular effects of sevoflurane in patients with myasthenia gravis (mg). we evaluated the neuromuscular effects of sevoflurane alone in patients with mg and in those with normal neuromuscular transmission. | 2007 | 17251207 |
| eating styles, overweight and obesity in young adult twins. | to explore the association of eating styles with overweight and obesity in young adults, controlling for identical genetic background in monozygotic twins. | 2007 | 17251930 |
| necrotizing fasciitis as a late complication of multimodal treatment for locally advanced head and neck cancer: a case report. | late complications of novel organ preservation multimodal protocols for the treatment of locally advanced head and neck cancer may be underreported in the literature. | 2007 | 17252595 |
| the effect of life-long thyroxine treatment and physical activity on bone mineral density in young adult women with congenital hypothyroidism. | normalization of plasma thyrotropin in t4-supplemented patients with thyroidal congenital hypothyroidism (ch) requires elevated plasma ft4-concentrations compared to patients with acquired thyroidal hypothyroidism. we investigated bone mineral density (bmd) in patients with ch. | 2006 | 17252693 |
| postnatal thyroid hormones for preterm infants with transient hypothyroxinaemia. | extremely premature infants are at risk of transient hypothyroxinaemia in the first weeks after birth. these low thyroid hormone levels are associated with an increased incidence of neonatal morbidity, mortality and longer term developmental impairments. thyroid hormone therapy might prevent these problems. | 2007 | 17253568 |
| prophylactic postnatal thyroid hormones for prevention of morbidity and mortality in preterm infants. | observational studies have shown an association between transiently low thyroid hormone levels in preterm infants in the first weeks of life (transient hypothyroxinaemia) and abnormal neurodevelopmental outcome. thyroid hormone replacement might prevent this. | 2007 | 17253571 |
| synthesis and biological studies of n-alkylated cyclic diamines. | several alkyl-substituted mesocyclic diamines were synthesized, and their interaction with dna were studied by melting-temperature measurements and the ethidium bromide (eb)-fluorescence competitive method. the supercoiled dna hydrolytic cleavage by 1,4-dioctyl-1,4-diazepan-6-ol (4) was supported by the evidence from free-radical quenching and t4-ligase ligation. preliminary pharmacological tests showed that only 1,4-dioctyl-1,4-diazepan-6-ol (4) had antitumor activity against hela cell lines in ... | 2007 | 17256733 |
| surgical resection for multifocal (t4) non-small cell lung cancer: is the t4 designation valid? | the current international staging system for lung cancer designates intralobar satellites as t4 disease. in this study, we sought to determine the impact of multifocal, intralobar non-small cell lung cancer (nsclc) on patient survival and its potential relevance to stage designation. | 2007 | 17257959 |
| comparative bioavailability of different formulations of levothyroxine and liothyronine in healthy volunteers. | to evaluate the relative bioavailability of t4 sodium and liothyronine sodium (t3), administered in single doses as oral solution (drops) and tablet forms, according to two separate study protocols. | 2006 | 17259789 |
| sectional neuroanatomy of the lower thoracic spine and chest. | this is the fourth in a series of articles on the spine. the first reviewed the anatomy of the neck; the second reviewed the upper thoracic spine and chest (t1-t4); and the third reviewed the middle thoracic spine and chest (t5-t8). the procedures performed in the lower thoracic spine include percutaneous biopsies of the liver and kidneys, percutaneous nephrolithotomy, spinal injections, radiofrequency ablations, electromyography of the diaphragm, trigger point injections, chemodenervation with ... | 2007 | 17259850 |
| oxaliplatin with raltitrexed and preoperative radiotherapy in t3-t4 extraperitoneal rectal cancer. a dose finding study. | the availability of new drugs offers the opportunity to improve the outcome of locally advanced rectal cancer. raltitrexed and oxaliplatin are effective in advanced colorectal cancer with acceptable toxicity and can act as radiation enhancers as shown in phase i-ii studies. the aim of the study was thus to determine the recommended dose of oxaliplatin concomitantly administered with raltitrexed and concurrent preoperative radiotherapy in patients with stage ii-iii extraperitoneal rectal cancer. | 2006 | 17260486 |
| thyroid hormone profile in acute coronary syndromes. | to describe thyroid hormone profile in patients with acute coronary syndromes (acs), divided into two groups: 1) unstable angina and/or non-st-segment elevation acute myocardial infarction (ua/nstemi); 2) st-segment elevation acute myocardial infarction (stemi), as well as in patients that progressed or not to death, according to the groups. | 2006 | 17262104 |
| head and neck reconstruction using infrahyoid myocutaneous flaps. | the use of pedicled myocutaneous flaps in head and neck reconstruction is widely accepted. here we describe our experience with infrahyoid flaps (ihfs) employed to cover surgical defects in the oral cavity and oropharynx in patients with benign and malignant tumors. the aim was to evaluate the success rate for infrahyoid myocutaneous flap procedures performed at a single institution. | 2006 | 17262158 |
| [prognostic and diagnostic value of telomerase in the head and neck cancer]. | telomerase is an enzyme responsible for maintaining the constant length of chromosomal telomers, which are necessary for normal function of eucaryotic cells. presence of active telomerase in neoplastic cells prevents shortening of telomers what makes this cells immortal. telomerase plays an important role in carcinogenesis. aim of this study was to investigate the activity of telomerase in head and neck tumors and assess its diagnostic and prognostic value. | 2006 | 17263245 |
| [malignant tumors of the nose and paranasal sinuses in the years 1992-2001]. | on the base of retrospective analysis of 927 cases of malignant neoplasms of the nose and paranasal sinuses, diagnosed and treated in 10 clinical centers in poland from 1992-2001, the assessment of basic epidemiological data, including the localization of tumor, and stage of local and clinical advancement of the disease at the time of diagnosis has been conducted. in analyzed period of 10 years the trends to change the mentioned above parameters has been examined. the index of morbidity in this ... | 2006 | 17263246 |
| [evaluation of chosen parameters of acute-phase reaction in children during pseudocroup according to their age]. | acute subglottic laryngitis (pseudocroup) usually occurs in infants and small children between 1 and 3 years of age. due to the viral etiology there are autumn-winter and winter-spring peaks of frequency of this disease observed. acute-phase proteins are a group of proteins whose concentration in the serum changes following variety of injuries such as bacterial, viral or parasitic infection. these changes are one of the features of an early, non-specific and highly complex reaction of the organi ... | 2006 | 17263248 |
| comparison between remnant and red-marrow absorbed dose in thyroid cancer patients submitted to 131i ablative therapy after rh-tsh stimulation versus hypothyroidism induced by l-thyroxine withdrawal. | in thyroidectomized patients, increased levels of thyroid stimulating hormone (tsh) are necessary to maximize i uptake. traditionally, this has been achieved by withdrawing l-thyroxine (l-t4) for 4-6 weeks, inducing hypothyroidism in patients. the availability of a genetically engineered version of the recombinant human tsh (rh-tsh) provides an alternative tool to enhance the tsh serum level without inducing hypothyroidism. in this paper the i remnant and red-marrow doses calculated in different ... | 2007 | 17264781 |
| ultrastructural observations on the elusive subtegumental cells of the viviparous gill monogenean, macrogyrodactylus clarii. | the ultrastructure of the tegument, including putative subtegumental cells, of the monogenean gill parasite macrogyrodactylus clarii is described for the first time. the lateral cells are secretory in nature and can be classified into four types: t1 producing elongated, electron-dense, bodies (t1); t2 manufacturing electron-lucent vesicles (t2); t3 producing thin, dump-bell shaped, electron-dense bodies (t3); and t4 containing lyzosome-like inclusions. morphologically, the t2 cells resemble thos ... | 2007 | 17265090 |
| nuclear localization of protein kinase ck2 catalytic subunit (ck2alpha) is associated with poor prognostic factors in human prostate cancer. | many genomic abnormalities have been identified in various subsets of prostate cancer, but until now, few genes have been associated with the progression of this cancer. high activity of protein serine/threonine kinase ck2 has been observed in various solid tumours and this alteration has been linked both to growth-related functions and to suppression of cellular apoptosis. here, we provide the first evidence for a strong association between a nuclear localization of ck2alpha, evaluated by immun ... | 2007 | 17267203 |
| design and numerical simulation of a dna electrophoretic stretching device. | dna stretching is now a key technology in emerging dna mapping devices such as direct linear analysis (dla), though dna stretching in a high throughput manner is still a challenging problem. in this work, we present a new microfluidic channel design to enhance dna stretching using kinematic analysis and brownian dynamics-finite element method (bd-fem). our group recently showed in experiments that the extensional electrophoretic field arising from a hyperbolic microcontraction can be utilized to ... | 2007 | 17268624 |
| cell-free co-synthesis of protein nanoassemblies: tubes, rings, and doughnuts. | we used a cell-free transcription/translation system to synthesize structural proteins of the t4 bacteriophage. we focused on two proteins that participate in the formation of the virus tail tube assembly. synthesized separately, the proteins assembled into their in vivo forms, namely one polymerized into rigid hollow nanotubes approximately 20 nm thick and hundreds of nanometers long, the other assembled into 10 nm tube-capping hexameric rings. co-synthesis of the two proteins, however, reveale ... | 2007 | 17269832 |
| the clinical utility of lens culinaris agglutinin-reactive thyroglobulin ratio in serum for distinguishing benign from malignant conditions of the thyroid. | traditionally, the follow-up of differentiated thyroid carcinoma consists of periodic withdrawal from l-t4-suppressive therapy to allow performance of a highly sensitive serum tg measurement to detect recurrences. we investigated lens culinaris agglutinin-reactive thyroglobulin ratios in serum to evaluate in usefulness for detection of thyroid carcinoma. | 2007 | 17270168 |
| kinematic analysis of the 100-m wheelchair race. | the purpose of this study was to compare the speed and selected stroke cycle characteristics during different phases of the 100-m wheelchair race for paraplegic athletes. four male and two female wheelchair racers in t4 classification and one male and three female athletes in t3 classification served as the participants. two s-vhs camcorders (60 fields/s) were panned horizontally to cover the first and second 50 m of the 100-m race, respectively. average speed, stroke length and frequency, conta ... | 2007 | 17270191 |
| us diagnosis of cervical recurrence in patients operated on thyroid cancer: sonographic features and clinical significance. | to describe the sonographic features of cervical recurrence in patient with thyroid cancer and review clinical significance. | 2007 | 17270376 |
| nutrient supplementation post ambulation in persons with incomplete spinal cord injuries: a randomized, double-blinded, placebo-controlled case series. | to examine effects of protein-carbohydrate intake on ambulation performance in persons with incomplete spinal cord injury (sci). | 2007 | 17270521 |
| large-scale study of clinical impact of psa velocity: long-term psa kinetics as method of differentiating men with from those without prostate cancer. | to assess the longitudinal prostate-specific antigen (psa) changes in a screening population with or without prostate cancer during a 10-year period. | 2007 | 17270635 |
| quality of life and functional status in patients with cancer of the oral cavity and oropharynx: pretreatment values of a prospective study. | we assessed the pretreatment health-related quality of life (hrqol) and functional status of patients with advanced oral and oropharyngeal cancer. eighty patients were investigated. hrqol was assessed by eortc qlq-c30/qlq-h&n35 questionnaires. functional status assessment comprised speech and oral function tests. the results revealed a wide range of hrqol and functional deficits before treatment. hrqol appeared to be related to some extent to tumor site (patients with oral tumors reported more p ... | 2007 | 17273840 |
| expression of the bacteriophage t4 lysozyme gene in tall fescue confers resistance to gray leaf spot and brown patch diseases. | tall fescue (festuca arundinacea schreb.) is an important turf and forage grass species worldwide. fungal diseases present a major limitation in the maintenance of tall fescue lawns, landscapes, and forage fields. two severe fungal diseases of tall fescue are brown patch, caused by rhizoctonia solani, and gray leaf spot, caused by magnaporthe grisea. these diseases are often major problems of other turfgrass species as well. in efforts to obtain tall fescue plants resistant to these diseases, we ... | 2008 | 17273914 |
| swallowing after major surgery of the oral cavity or oropharynx: a prospective and longitudinal assessment of patients treated by microvascular soft tissue reconstruction. | the aim of this study was to analyze swallowing outcome in advanced oral/oropharyngeal cancer patients treated with microvascular reconstructive surgery and adjuvant radiotherapy. | 2007 | 17274054 |
| reduction of plasma taurine level in children affected by osteogenesis imperfecta during bisphosphonate therapy. | osteogenesis imperfecta (oi) is a heritable disease of connective tissue characterized by increased bone fragility. to date, bisphosphonates seem to be the most promising therapy, at least for children. in the last decade experimental and clinical studies indicate that several amino acids are implicated in bone mineralization. particularly, taurine is localized in matrices of the bone and can regulate osteoblast metabolism with antiosteopenic effect. to investigate a possible interaction between ... | 2007 | 17275249 |
| total laryngectomy and t3-t4 laryngeal cancer without other adverse histopathology. | we sought to determine the postoperative management, incidence of tumor recurrence in the neck, and outcome in laryngeal cancer patients whose risk for tumor relapse is not clear. | 2007 | 17275558 |
| prevalence and numbers of coliphages and campylobacter jejuni bacteriophages in new zealand foods. | vegetable samples were tested for the presence of coliphages. none of the 55 samples contained these phages at concentrations greater than 10 g(-1) (the limit of detection). spiking and recovery experiments indicated that the method was efficient at detecting coliphage t4 added to the food, and so it was concluded that phage titres were not being falsely underestimated. in addition 51 samples of chicken skin from retail portions were tested for the presence and numbers of coliphages and for pres ... | 2007 | 17276534 |
| structural characterization of 4-bromostyrene self-assembled monolayers on si(111). | organic functionalization of silicon holds promise for a variety of applications ranging from molecular electronics to biosensing. because the performance and reliability of organosilicon devices will be intimately tied to the detailed structure of the organic adlayers, it is imperative to develop systematic strategies for forming and characterizing self-assembled monolayers (sams) on silicon with submolecular spatial resolution. in this study, we use 4-bromostyrene for the photochemical growth ... | 2007 | 17279673 |
| thyroid hormone-induced demineralisation of the vertebral skeleton of the eel, anguilla anguilla. | the role of thyroid hormones (th) in bone remodelling is controversial. indeed, in humans, while they are necessary for normal growth and development, their overproduction can induce important mineral bone loss and osteoporosis. intense bone resorption is a natural phenomenon also observed in some teleosts, during reproductive migration and fasting. our work aimed at investigating the effects of chronic treatments with th (thyroxin, t4 or triiodothyronine, t3) on bone resorption in a migratory f ... | 2007 | 17280664 |
| coherence characteristics of gamma-band eeg during rest and cognitive task in mci and ad. | the aim of this study is to investigate whether eeg coherence during different functional states facilitates the detection of ad-related eeg changes; and which brain regions these changes were. the eegs in both rest and performing the cognitive task states of 3 groups was recorded for coherence measure. the 3 groups are the mild cognitive impairment (mci) group, alzheimer's disease(ad) and the healthy control group. in rest state, coherence value of eeg for ad group was lower than that in other ... | 2005 | 17282809 |
| trendelenburg position with hip flexion as a rescue strategy to increase spinal anaesthetic level after spinal block. | when the level achieved by a spinal anaesthetic is too low to perform surgery, patients are usually placed in the trendelenburg position. however, cephalad spread of the hyperbaric spinal anaesthetics may be limited by the lumbar lordosis. the trendelenburg position with the lumbar lordosis flattened by hip flexion was evaluated as a method to extend the analgesic level after the administration of hyperbaric local anaesthetic. | 2007 | 17283005 |
| pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and cowden disease pathogenesis. | inactivation and silencing of the tumor suppressor pten are found in many different epithelial tumors, including thyroid neoplasia. cowden disease patients, who harbor germ-line pten mutations, often display thyroid abnormalities, including multinodular goiter and follicular adenomas, and are at increased risk of thyroid cancer. to gain insights into the role pten plays in thyroid function and disease, we have generated a mouse strain, in which cre-mediated recombination is used to specifically ... | 2007 | 17283127 |
| [expression of survivin in nasal and paranasal sinus carcinoma]. | to assess the protein expression of a new inhibitor of apoptosis, survivin, and its correlation with spontaneous apoptosis, tumor clinicopathological parameters and prognosis in nasal and paranasal sinus carcinoma (npsc). | 2006 | 17283539 |
| recombinant thyrotropin in the diagnosis of congenital hypothyroidism. | a modern approach to congenital hypothyroidism requires a definitive diagnosis of the underlying mechanisms; this can be achieved within the first weeks of life. when uncertainty persists, treatment is commenced, and the definitive diagnosis of congenital hypothyroidism is deferred to the age of 3 yr. | 2007 | 17284628 |
| [surgery treatment of rectal cancer]. | surgical resection is the only curative procedure for carcinoma of the rectum. heald's development of total mesorectal excision has made it the standard approach for mobile, non-fixed tumors; it permits optimal local control with less than 10% local recurrence at five years and minimizes nerve damage and genito-urinary complications. although initial short-term results of laparoscopic approaches are very promising, the final role of laparoscopy has not yet been established. neo-adjuvant radiothe ... | 2006 | 17285082 |
| survival following complete resection of multifocal t4 node-negative nsclc: a retrospective study. | multifocal nsclc in the same lobe are staged as t4. this study was designed to assess the impact of multifocal nsclc in the same lobe on survival in completely resected node-negative patients to determine whether the t4 (stage iii b) designation is valid. | 2007 | 17285473 |
| [the quantitative evaluation of the serum acute phase proteins (app) of patients undergoing a curative resection for non-small cell lung cancer (nsclc)]. | the aim of this study was to quantitatively evaluate serum app in patients undergoing the radical resection for nsclc. the quantitative changes in app were correlated with the cancer type, clinical staging and grading and the procedure type. also, the impact of selected post-operative complications on the app serum concentrations was evaluated. 46 patients undergoing surgery secondary to nsclc in the years 2003-2004 were analyzed. the patients' age varied from 45 to 77 years with an average of 6 ... | 2006 | 17288188 |
| [clinical research of thoracoscopy-assisted mini-open surgery for anterior column reconstruction of thoracic spine tuberculosis]. | to evaluate the clinic effects of thoracoscopy-assisted mini-open surgery for anterior column reconstruction of thoracic spine tuberculosis. | 2006 | 17288833 |
| modular architecture of the t4 phage superfamily: a conserved core genome and a plastic periphery. | among the most numerous objects in the biosphere, phages show enormous diversity in morphology and genetic content. we have sequenced 7 t4-like phages and compared their genome architecture. all seven phages share a core genome with t4 that is interrupted by several hyperplastic regions (hprs) where most of their divergence occurs. the core primarily includes homologues of essential t4 genes, such as the virion structure and dna replication genes. in contrast, the hprs contain mostly novel genes ... | 2007 | 17289101 |
| l-thyroxine augmentation of serotonergic antidepressants in female patients with refractory depression. | triiodothyronine (t3) augmentation in treatment-resistant depression had been successfully performed with both tricyclic as well as with ssri antidepressants. in this paper, the efficacy of addition of moderate dose of l-thyroxine (t4) to serotonergic antidepressants in refractory depression was evaluated. | 2007 | 17289154 |
| homing endonuclease i-teviii: dimerization as a means to a double-strand break. | homing endonucleases are unusual enzymes, capable of recognizing lengthy dna sequences and cleaving site-specifically within genomes. many homing endonucleases are encoded within group i introns, and such enzymes promote the mobility reactions of these introns. phage t4 has three group i introns, within the td, nrdb and nrdd genes. the td and nrdd introns are mobile, whereas the nrdb intron is not. phage rb3 is a close relative of t4 and has a lengthier nrdb intron. here, we describe i-teviii, t ... | 2007 | 17289754 |
| [impact of intermittent hypobaric hypoxia on the thyroid morphofunctional state in experimental hyperthyroidism]. | within 5 days of hypoxia there was an increase in thyroid functional activity, but on days 15-30 there was a decrease in t3 and t4 concentrations and an increase in thyroid-stimulating hormone. clear correlations were found between the morphometric indices of the thyroid epithelium and the blood concentration of t3 and t4. there was a relationship between the levels of thyroid hormones and the state of the cardiovascular and respiratory systems. | 2006 | 17290891 |
| [a case of hyperthyroidism due to functioning metastasis of differentiated thyroid carcinoma. discussion and literature review]. | we report on a very rare case of hyperthyroidism due to multiple autonomously functioning bone metastasis of papillary thyroid cancer in a 79-year-old woman. this situation remains extremely uncommon, as shown by our review of the literature; only 47 similar cases have been published from 1946 to 2005. the pathogenic mechanism remains largely unknown in spite of several hypotheses (conjunction in volume and differentiation, auto-antibodies). hyperthyroidism can be severe, and often t3 levels are ... | 2007 | 17292845 |
| structural rigidity of a large cavity-containing protein revealed by high-pressure crystallography. | steric constraints, charged interactions and many other forces important to protein structure and function can be explored by mutagenic experiments. research of this kind has led to a wealth of knowledge about what stabilizes proteins in their folded states. to gain a more complete picture requires that we perturb these structures in a continuous manner, something mutagenesis cannot achieve. with high pressure crystallographic methods it is now possible to explore the detailed properties of prot ... | 2007 | 17292912 |
| herpes zoster in the t4 dermatome: a possible cause of breastfeeding strike. | the authors report a case of breastfeeding strike temporally related to the onset of a herpes zoster prodrome involving the left breast. | 2007 | 17293553 |
| hoc protein regulates the biological effects of t4 phage in mammals. | we previously investigated the biological, non-antibacterial effects of bacteriophage t4 in mammals (binding to cancer cells in vitro and attenuating tumour growth and metastases in vivo); we selected the phage mutant hap1 that was significantly more effective than t4. in this study we describe a non-sense mutation in the hoc gene that differentiates bacteriophage hap1 and its parental strain t4. we found no substantial effects of the mutation on the mutant morphology, and its effects on electro ... | 2007 | 17294171 |
| expression of neutral endopeptidase (nep/cd10) on pancreatic tumor cell lines, pancreatitis and pancreatic tumor tissues. | neutral endopeptidase (nep/cd10) is a cell surface zinc metalloprotease cleaving peptide bounds on the amino terminus of hydrophobic amino acids and inactivating multiple physiologically active peptides. loss or decrease in nep/cd10 expression have been reported in many types of malignancies, but the role of nep/cd10 in pancreatic carcinoma has not yet been identified. using real-time rt-pcr, flow cytometry as well as immunohistochemistry, nep/cd10 expression was quantified in both pancreatic ca ... | 2007 | 17294442 |
| [gene fragments cloned and immune recognition studied preliminarily for desmoglein 4 in pemphigus vulgaris]. | to amplify the nucleotide sequences of desmoglein 4 (dsg4) extracellular domains (ec1-4) from human skin tissue, and then to investigate their roles in pemphigus vulgans (pv) pathogenesis. | 2007 | 17294735 |
| reduction of eeg myogenic artifact with botulinum toxin during video-eeg monitoring. | to determine whether eeg myogenic artifact during video-eeg monitoring (vem) is reduced with targeted scalp botulinum toxin (btx-a) injections. | 2007 | 17295626 |
| fatigue experiences in hepatocellular carcinoma patients during six weeks of stereotactic radiotherapy. | to compare fatigue experiences and related factors during the first 6 weeks of stereotactic radiotherapy (srt) for liver cancer patients with and without fatigue before srt. | 2007 | 17296818 |
| phase ii study of neoadjuvant docetaxel, vinorelbine, and trastuzumab followed by surgery and adjuvant doxorubicin plus cyclophosphamide in women with human epidermal growth factor receptor 2-overexpressing locally advanced breast cancer. | to evaluate the combination of docetaxel, vinorelbine, and trastuzumab as neoadjuvant therapy for human epidermal growth factor receptor 2 (her2)--overexpressing breast cancer. | 2007 | 17296975 |
| the effects of l-thyroxine treatment on qt dispersion in primary hypothyroidism. | hypothyroidism has various cardiovascular manifestation and exhibits electrocardiographic change. the qt dispersion on surface ecg reflects regional variations in myocardial repolarization. the effect of l-thyroxine treatment on ecg parameters, such as qt dispersion, in patients with primary hypothyroidism were investigated. this study involved 18 patients (3 men, 15 women, ages: 48+/-18 yr) with primary hypothyroidism. all patients were checked with a standard 12-lead ecg before and after l-thy ... | 2007 | 17297262 |
| justification for staging of epidermoid anal carcinoma after salvage surgery: a pathological guideline. | the currently accepted first line treatment for epidermoid anal cancer is chemoradiotherapy (crt). tumour size and adjacent organ involvement are the key in the pretreatment assessment for t1-t4 tumours respectively. residual or recurrent disease following initial crt, is best treated by salvage anorectal excision. pathological staging systems of resections were historically validated when surgery was the primary treatment and are therefore in need of revision. we propose a new pathological stag ... | 2007 | 17298622 |
| [application of magnetic resonance imaging to clinical classification of nasopharyngeal carcinoma]. | the clinical classification of nasopharyngeal carcinoma (npc) depends mainly on the materials of medical imaging. this study was to investigate the application of magnetic resonance imaging (mri) to the clinical classification of npc. | 2007 | 17298746 |
| improved non-invasive t-staging in non-small cell lung cancer by integrated 18f-fdg pet/ct. | in this prospective study, reliability of integrated (18)f-fdg pet/ct for staging of nsclc was evaluated and compared to mdct or pet alone. | 2007 | 17299649 |
| comparative study of specific ebv antibodies between children manifest classic triad of mononucleosis with unaffected children in hazrat rasool akram hospital (1998-2000). | epstein barr virus (ebv) is one of seven known herpes virus pathogenic for humans.since it is ubiquitous, it infects nearly 95% of individuals worldwide by adulthood .ebv is the etiologic agent of infectious mononucleosis(tm)and is implicated in burkitt lymphoma,nasopharyngeal carcinoma and x-linked lymphoproliferative syndrome.diagnosis of tm based upon clinical manifestations in conjunction with hematologic evidence for lymphocytosis;and serological changes such as heterophil antibody and or a ... | 2003 | 17301361 |
| should 'low-risk' thyroid cancer patients with residual thyroglobulin be re-treated with iodine 131? | the american consensus statement on patients with low-risk thyroid cancer, published in 2003, suggests repeat (131)i therapy if the thyroglobulin value is elevated at first follow-up. we evaluated this strategy in our practice. | 2007 | 17302864 |