| use of laryngeal mask airway compared to endotracheal tube with positive-pressure ventilation in anesthetized swine. | to compare the ease of placement and ventilatory parameters of a laryngeal mask airway (lma) with an endotracheal tube (ett) in anesthetized swine during positive-pressure ventilation (ppv). | 2007 | 17490468 |
| fibroepithelial hamartoma in a domestic pig. | this case report is the first description of a fibroepithelial hamartoma in a pig. the dysplasia, which covered half of the face of the newborn piglet, did not increase in relative size until the animal was euthanatized at 6 months of age. histologic examination revealed a moderate orthokeratotic hyperkeratosis with variable degrees of epithelial proliferation. the main body of the dysplasia consisted of collagenous fibers. in addition, some proliferating small blood vessels as well as focally g ... | 2007 | 17491090 |
| proof-of-concept study of the aer-o-scope omnidirectional colonoscopic viewing system in ex vivo and in vivo porcine models. | the limited angle of view of standard colonoscopes means that lesions can be missed. a multidirectional viewing system (omnivision) has been developed recently and has been incorporated into the aer-o-scope (gi view ltd., ramat gan, israel), a disposable, self-propelling, and self-navigating colonoscope. the objectives of this study were to qualitatively assess the sensitivity of this viewing system in an ex vivo porcine polyp induction model, and to demonstrate its feasibility and safety in liv ... | 2007 | 17516347 |
| skin changes following minor trauma. | bruises are currently evaluated by visual inspection, and little is known about the first phase after injury. the temporal development of fresh injuries must be accurately described to be able to age bruises in a reliable manner. color changes in a bruise caused by hemoglobin breakdown products will depend on the severity of the trauma, and thus on the local immune response in the skin. it is therefore important to relate the nature of the impact to the temporal tissue responses. | 2007 | 17523178 |
| transgastric cholecystectomy: transgastric accessibility to the gallbladder improved with the semf method and a novel multibending therapeutic endoscope. | transgastric cholecystectomy is thought to technically and anatomically challenge a single entry flexible endoscopic approach. | 2007 | 17531637 |
| an animal training model for endoscopic treatment of zenker's diverticulum. | zenker's diverticulum (zd) is an uncommon disease, which is typically treated surgically. the alternative to surgery is a diverticulotomy, performed endoscopically. given the rarity of this condition, it is not possible to obtain training. there has been no animal model identified that resembles the disease in human beings. | 2007 | 17531640 |
| histological and histomorphometric investigation of the condylar cartilage of juvenile pigs after anterior mandibular displacement. | the condylar cartilage of the mandible is considered a secondary growth center and represents a joint cartilage different from other cartilage structures regarding its histological structure, its histochemical and immunohistochemical properties and its growth pattern. this study aimed to histologically and histomorphometrically investigate the condylar cartilage after anterior mandibular displacement similar to functional orthopedic treatment. a total of 12 pigs (sus scrofa domesticus) aged 10 w ... | 2007 | 17534034 |
| characteristics of primary and immortalized fibroblast cells derived from the miniature and domestic pigs. | the pig, sus scrofa domestica includes both the miniature and commercial domestic breed. these animals have influenced the human life and economies and have been studied throughout history. although the miniature breeds are more recent and have increasingly been used in a variety of biomedical studies, their cell lines have rarely been established. therefore, we sought to establish primary and immortal cell lines derived from both the miniature and domestic pig to better enable insight into poss ... | 2007 | 17543094 |
| treating ischemic left ventricular dysfunction with hypertonic saline administered after coronary occlusion in pigs. | the effects of hypertonic saline on ventricular function are controversial, whether it is increasing contractility or preload. there are no data, however, on the influence of hypertonic saline in a stunned myocardium. | 2007 | 17544894 |
| the quality of chest compressions during cardiopulmonary resuscitation overrides importance of timing of defibrillation. | we address the quality of chest compressions and the impact on initial defibrillation or initial chest compressions after sudden death. | 2007 | 17550931 |
| cytochrome p450arom, androgen and estrogen receptors in pig sperm. | androgens and estrogens are crucial for mammalian sperm differentiation but their role in biology of mature male gamete is not still defined. the expression of proteins involved in the biosynthesis and action of these steroid hormones has been demonstrated in human spermatozoa, but very few data have been reported in mature sperm from non human species. the purpose of the current study was to investigate the expression of aromatase (p450arom), estrogen (eralpha/erbeta) and androgen (ar) receptor ... | 2007 | 17553131 |
| [sex-linked erythrocyte antigens of the domestic pig]. | it has been demonstrated that the domestic pig has a blood group systems whose haplotypes (complex alleles) are formed by at least three closely linked loci that are located, like the mic2 locus of human blood group systems, in the homologous region of sex chromosomes. | 2007 | 17555129 |
| effectiveness and renal tolerance of multidetector helical ct with gadobutrol: results of a comparative porcine study. | to prospectively evaluate the safety and effectiveness of high doses of 1 mol/l gadobutrol as a contrast agent for computed tomography (ct). | 2007 | 17562809 |
| the no donor sin-1 improves intestinal-arterial p(co(2)) gap in experimental endotoxemia: an animal study. | dysfunction of the microcirculation is a prominent feature of sepsis and endotoxemia. recently, it has been shown that microcirculatory alterations are completely reversed by local or systemic application of vasodilators in severely septic patients. therefore, we investigated the influence of vasodilator therapy on microcirculatory dysfunction of the ileum during endotoxic shock in a prospective, controlled animal study. | 2007 | 17567269 |
| alternative splicing and expression profile analysis of expressed sequence tags in domestic pig. | domestic pig (sus scrofa domestica) is one of the most important mammals to humans. alternative splicing is a cellular mechanism in eukaryotes that greatly increases the diversity of gene products. expression sequence tags (ests) have been widely used for gene discovery, expression profile analysis, and alternative splicing detection. in this study, a total of 712,905 ests extracted from 101 different non-normalized est libraries of the domestic pig were analyzed. these est libraries cover the n ... | 2007 | 17572361 |
| first isolation of haemophilus parasuis and other nad-dependent pasteurellaceae of swine from european wild boars. | haemophilus parasuis is a colonizer of the upper respiratory tract of pigs and the etiological agent of glässer's disease, which is characterized by a fibrinous polyserositis, meningitis and arthritis. glässer's disease has never been reported in wild boar (sus scrofa), although antibodies against h. parasuis have been detected. the goal of this study was to confirm the presence of this bacterium in wild boar by bacterial isolation and to compare the strains to h. parasuis from domesticated pigs ... | 2007 | 17574352 |
| microwave ablation with multiple simultaneously powered small-gauge triaxial antennas: results from an in vivo swine liver model. | to prospectively investigate the ability of a single generator to power multiple small-diameter antennas and create large zones of ablation in an in vivo swine liver model. | 2007 | 17581900 |
| identification of genotype 4 hepatitis e virus strains from a patient with acute hepatitis e and farm pigs in bali, indonesia. | a previous study revealed that antibodies to hepatitis e virus (hev) (anti-hev) are highly prevalent among healthy individuals and farm pigs in bali, indonesia, and suggested that hev infection may occur via zoonosis among balinese people. however, there were no reports of acute hepatitis e in bali. to elucidate whether balinese hev strains recovered from infected humans and pigs have significant sequence similarity, serum samples obtained from 57 patients (age, mean +/- standard deviation, 31.1 ... | 2007 | 17596841 |
| positive effect of darbepoetin on peri-infarction remodeling in a porcine model of myocardial ischemia-reperfusion. | erythropoietin (epo) has anti-apoptotic and pro-angiogenic effects in rodent models of myocardial infarction (mi). we tested the hypothesis that a long-acting epo derivative (darbepoetin) has a beneficial effect on infarct size and peri-infarct remodeling in a clinically relevant large animal model of ischemia-reperfusion. a human acute mi scenario was simulated in 16 domestic pigs by inflating an angioplasty balloon in the proximal left circumflex (lcx) artery for 60 min. the animals were rando ... | 2007 | 17597149 |
| analysis of the full-length genome of hepatitis e virus isolates obtained from farm pigs in mongolia. | although no outbreaks of hepatitis e have been reported in mongolia, a significant proportion of the general population had antibodies to hepatitis e virus (hev). to investigate whether pigs are possible reservoirs of hev in mongolia, serum samples obtained from 243 2- or 3-month-old pigs on four swine farms surrounding ulaanbaatar, the capital city of mongolia, were tested for the presence of anti-hev antibodies and hev rna. overall, 223 pigs (91.8%) tested positive for anti-hev, while 89 pigs ... | 2007 | 17597486 |
| laser-induced thermotherapy for lung tissue--evaluation of two different internally cooled application systems for clinical use. | thermal ablation techniques like radiofrequency or laser-induced thermotherapy (litt) are increasingly used to treat tumors of parenchymatous organs. minimal access, parenchymal preservation, and a low complication rate render them suitable for pulmonary tumors as well. their successful clinical application depends on the induction of sufficiently large lesions and a knowledge of the energy parameters required for complete thermal ablation. the aim of this study was to establish a dose-response ... | 2008 | 17599236 |
| [monitoring of infectious diseases among wild boars]. | sixty-seven serum samples and 43 pathological material samples from wild boars, taken in 5 regions of russia and in the kharkov region of the ukraine in 2002 to 2005 were studied. wild boars in some regions of russia were shown to be carriers of aujeszky's disease virus, porcine parvovirus, porcine circovirus type 2, lymphotropic herpesvirus-1, porcine cytomegalovirus, mycoplasma hyopneumoniae and pasteurella multocida. the classical swine fever (csf) virus genome was detected by polymerase chai ... | 2007 | 17601049 |
| retrospective analyses of serum lipids and lipoproteins and severity of disease in 60co-irradiated sus scrofa domestica and macaca mulatta. | profound neutropenia that provides an opportunity for infections to develop into sepsis remains an important cause of morbidity and mortality in patients after irradiation. human clinical studies find extremely low concentrations of cholesterol (less than 120 mg/dl) associated with high risk of death in critically ill adult patients admitted to intensive care units. this retrospective study was initiated as part of separate investigations of radiation-induced acquired infections in 2 large anima ... | 2007 | 17605346 |
| infertile finnish yorkshire boars carry a full-length line-1 retrotransposon within the kpl2 gene. | the kpl2 gene is expressed predominantly in cells with cilia or flagella. we have previously demonstrated that a large intronic insertion in kpl2 is associated with immotile sperm cells and infertility in the domesticated pig (sus scrofa). to fully characterize the structure of the mutation, we have now cloned and sequenced the insertion. the data identified the presence of a long interspersed nuclear element-1 (line-1) encoding all activities required for retrotransposition, including a 5'-untr ... | 2007 | 17610085 |
| peptidergic and nitrergic innervation of the pineal gland in the domestic pig: an immunohistochemical study. | the presence and co-localization of vasoactive intestinal polypeptide (vip), peptide n-terminal histidine c-terminal isoleucine (phi), pituitary adenylate cyclase-activating peptide (pacap), somatostatin (som), calcitonin gene-related peptide (cgrp), substance p (sp) and the neuronal isoform of nitric oxide synthase (nos) were studied in neuronal structures of the pig pineal gland. paraformaldehyde-fixed pineals of 3-month-old gilts were sliced into serial cryostat sections, which were subjected ... | 2007 | 17617110 |
| arginine vasopressin during sinus rhythm: effects on haemodynamic variables, left anterior descending coronary artery cross sectional area and cardiac index, before and after inhibition of no-synthase, in pigs. | we have shown previously that arginine vasopressin (avp) given during sinus rhythm increases mean arterial blood pressure (map) and left anterior descending (lad) coronary artery cross sectional area. avp was assumed to result in vasodilatation via activation of the endothelial nitric oxide system. the purpose of the present study was to assess the effects of avp before and after no-inhibition. nine domestic pigs were instrumented for measurement of haemodynamic variables using micromanometer-ti ... | 2007 | 17621455 |
| a high utility integrated map of the pig genome. | the domestic pig is being increasingly exploited as a system for modeling human disease. it also has substantial economic importance for meat-based protein production. physical clone maps have underpinned large-scale genomic sequencing and enabled focused cloning efforts for many genomes. comparative genetic maps indicate that there is more structural similarity between pig and human than, for example, mouse and human, and we have used this close relationship between human and pig as a way of fa ... | 2007 | 17625002 |
| histopathological classification of systemic mycobacterium avium complex infections in slaughtered domestic pigs. | the aim of this study was to classify the histopathological features of pigs infected with mycobacterium avium complex (mac). we used slaughtered pig organs systemically infected with mac. the results showed granulomatous lesions which were observed predominantly in the digestive organs and regional lymph nodes rather than respiratory organs. the histological picture showed a wide range of granulomatous stages from exudative to fibrotic reactions to the mac infection. eosinophils and giant cells ... | 2008 | 17629560 |
| the temperature-dependent viscoelasticity of porcine lumbar spine ligaments. | a uniaxial tensile loading study of 13 lumbar porcine ligaments under varying environmental temperature conditions. | 2007 | 17632382 |
| implication of cortisol and 11beta-hydroxysteroid dehydrogenase enzymes in the development of porcine (sus scrofa domestica) ovarian follicles and cysts. | this study investigated cortisol inactivation by 11beta-hydroxysteroid dehydrogenase (11beta hsd) enzymes in porcine granulosa cells from antral follicles at different developmental stages and in ovarian cysts. in granulosa cells, cortisol oxidation increased threefold with antral follicle diameter (p < 0.001). this trend was paralleled by a threefold increase in nadp(+)-dependent 11beta-dehydrogenase activity in granulosa cell homogenates with follicle diameter. intact granulosa cells from ovar ... | 2007 | 17636169 |
| rapid communication: transvaginal single-port notes nephrectomy: initial laboratory experience. | natural orifice translumenal endoscopic surgery (notes) using purpose-built equipment has never been applied to urologic surgery. herein, we present our initial experience with a trans-vaginal single-port notes nephrectomy. | 2007 | 17638562 |
| effects of commonly used hemostatic agents on the porcine collecting system. | topical hemostatic agents have been particularly useful for preventing bleeding in tubeless percutaneous nephrolithotomy. in the present study, we investigated the effect of gelatin matrix hemostatic sealant (floseal), fibrin glue (tisseel,), polyethylene glycol polymers (coseal), and bovine serum albumin/ glutaraldehyde (bioglue) in the pig urinary collecting system after injection through a percutaneous nephrostomy (pcn) tract. | 2007 | 17638564 |
| [gastro-entero anastomosis with flexible endoscope with the help of rare-earth magnets on biosynthetic model made of the gastrointestinal tract of slaughtered pigs]. | gastro-entero anastomosis with flexible endoscope with the help of rare-earth magnets on biosynthetic model made of the gastrointestinal tract of slaughtered pigs | 2007 | 17649852 |
| alkali-labile sites in sperm cells from sus and ovis species. | constitutive alkali-labile sites (alss) have been investigated using a protocol of dna breakage detection-fluorescence in situ hybridization (dbd-fish) in sperm cells from sus domesticus (pig), ovis gmelini musimon (mouflon) and ovis aries (sheep). the results were compared with those obtained using leucocytes from the same species. whole comparative genomic hybridization (w-cgh) showed that most of the constitutive alss in somatic and germ line cells in all species examined were constrained to ... | 2008 | 17651406 |
| modified ileal conduit stoma: safety of freeing the mesenteric edge of the distal part of ileal conduits. | an ileal conduit is created in about half of all urinary diversions. difficulties in constructing an abdominal stoma in morbidly obese patients can be challenging, especially if the patient has a short mesentery. excessive traction on the mesentery in an attempt to pass the distal segment of ileum through the thick abdominal wall may result in ischemia of the whole segment blood supply. we evaluated the safety of freeing the terminal portion of the conduit from its mesentery to facilitate easy p ... | 2007 | 17655874 |
| comparison of novel tissue apposing device and standard anastomotic technique for vesicourethral anastomoses. | to evaluate a novel sutureless tissue apposing vesicourethral anastomosis (vua) device in a porcine model and compare it with standard laparoscopically sutured vua. | 2007 | 17656246 |
| vasopressin improves survival in a porcine model of abdominal vascular injury. | we sought to determine and compare the effects of vasopressin, fluid resuscitation and saline placebo on haemodynamic variables and short-term survival in an abdominal vascular injury model with uncontrolled haemorrhagic shock in pigs. | 2007 | 17659093 |
| melagatran for thromboprophylaxis after mechanical valve implantation: results in a heterotopic porcine model. | melagatran, the active form of ximelagatran, is a novel, direct thrombin inhibitor that does not have a narrow therapeutic window regarding hemorrhagic and thromboembolic events. we aimed to determine whether melagatran would be effective in preventing thrombus formation on heterotopically placed mechanical heart valves. | 2007 | 17662773 |
| patent foramen ovale closure by radiofrequency thermal coaptation: first experience in the porcine model and healing mechanisms over time. | percutaneous transcatheter patent foramen ovale (pfo) closure is now standard practice and may limit embolic complications for at least 10 years. implantable pfo closure devices may be complicated by thrombosis, infection, device fracture, or embolization. a novel strategy uses radiofrequency-based thermal energy to seal pfo membranes, with no implanted device. we successfully used this method and examined histopathologic events in swine to characterize safety and efficacy. | 2007 | 17664371 |
| intra-genotypic resolution of african swine fever viruses from an east african domestic pig cycle: a combined p72-cvr approach. | two of the 22 presently recognised african swine fever (asf) virus p72 genotypes are genetically homogeneous and are associated with domestic pig cycles. of these, genotype viii comprises just two p72 variants, designated 'a' and 'b' in this study, and is confined to four east african countries where it has caused numerous outbreaks between 1961 and 2001. in order to resolve relationships within this homogeneous genotype, the central variable region (cvr) of the 9rl open reading frame of 38 viru ... | 2007 | 17674176 |
| strategies for the elimination of taeniasis/cysticercosis. | advances in the field of neurocysticercosis continue to shape our understanding of the disease and our efforts to control it. several attempts have been made to eradicate the disease with active interventions such as changing domestic pig-raising practices, mass chemotherapy of porcine cysticercosis and taeniasis, selective detection and treatment of taeniasis, and community health education. moreover, ongoing progress in the diagnosis of taeniasis and the development of a porcine vaccine agains ... | 2007 | 17681546 |
| metric analysis of the upper space of the temporomandibular joint (tmj) in pigs (sus scrofa domestica) for evaluation of the pig as a model for arthroscopic tmj surgery. | minimally invasive arthroscopic surgery of the temporomandibular joint (tmj) is more technically demanding than procedures in larger joints. the acquisition of adequate arthroscopic skills for tmj surgery requires extensive specialized training that can hardly be obtained from patients. in order to introduce a proper animal model for tmj arthroscopy, this study focuses on the morphology of the upper joint cavity of pigs at different ages. plastic casts of the upper joint cavity were obtained fro ... | 2007 | 17695994 |
| species-specific visitation and removal of baits for delivery of pharmaceuticals to feral swine. | within the domestic swine industry there is growing trepidation about the role feral swine (sus scrofa) play in the maintenance and transmission of important swine diseases. innovative disease management tools for feral swine are needed. we used field trials conducted in southern texas from february to march 2006 to compare species-specific visitation and removal rates of fish-flavored and vegetable-flavored baits with and without commercially available raccoon (procyon lotor) repellent (trial 1 ... | 2007 | 17699086 |
| the prevalence, organ distribution and fertility of cystic echinoccosis in feral pigs in tropical north queensland, australia. | an investigation was carried out to study the prevalence of echinococcus granulosus hydatidosis in feral pigs (sus domesticus) in the charters towers region of tropical north queensland. data were collected from a total of 238 carcasses, which were hunted and shot in the burdekin river catchment area. organs of the abdominal, thoracic, and pelvic cavities were examined for the presence of hydatid cysts. in the laboratory, cysts and hydatid cyst fluids were examined under a stereoscopic binocular ... | 2007 | 17708154 |
| 11beta-hydroxysteroid dehydrogenase enzymes in the testis and male reproductive tract of the boar (sus scrofa domestica) indicate local roles for glucocorticoids in male reproductive physiology. | 11beta-hydroxysteroid dehydrogenase (11betahsd) enzymes modulate the target cell actions of corticosteroids by catalysing metabolism of the physiological glucocorticoid (gc), cortisol, to inert cortisone. recent studies have implicated gcs in boar sperm apoptosis. hence, the objective of this study was to characterise 11betahsd enzyme expression and activities in the boar testis and reproductive tract. although 11betahsd1 and 11betahsd2 mrna transcripts and proteins were co-expressed in all tiss ... | 2007 | 17709565 |
| laparoscopic diagnostics of acute bowel ischemia using ultraviolet light and fluorescein dye: an experimental study. | the aim of the study was to show the diagnostic potential of laparoscopy using fluorescein dye and ultraviolet light in acute bowel ischemia. | 2007 | 17710051 |
| brain metabolism during a decrease in cerebral perfusion pressure caused by an elevated intracranial pressure in the porcine neocortex. | cranial hypertension coincides with a reduction in cerebral blood flow as well as in oxygen delivery and influences outcome. in this study, we monitored changes in energy-related metabolites in the porcine cortex during an increase of intracranial pressure (icp) and to determine the level at which damage occurs. | 2007 | 17717234 |
| hypothalamic neurons innervating fat tissue in the pig express leptin receptor immunoreactivity. | while leptin receptors have been found in both the autonomic ganglion neurons and the hypothalamic nuclei, studies dealing with the projections from the central nervous system to the adipose tissue have been conducted mainly in laboratory animals. therefore, the purpose of our study was to establish whether hypothalamic neurons are transsynaptically connected to adipose tissue depots in the pig, and if these neurons express leptin receptor immunoreactivity. pseudorabies virus (prv; bartha's k st ... | 2007 | 17720315 |
| the characteristics of head wounds inflicted by "humane killer" (captive-bolt gun)--a 15-year study. | the "humane killer" or captive-bolt gun, is the tool/weapon widely used in meat industry and private farmer households for slaughtering animal stock. out of 17,250 autopsies performed at the institute of forensic medicine in novi sad during the 15-year period (1991-2005), 29 cases of suicides and two homicides were committed by captive-bolt pistols. wounds inflicted by captive-bolt guns have specific morphological features, distinctive from wounds made by other kinds of hand firearms. selected f ... | 2007 | 17767661 |
| intestinal toxicity induced by 5-fluorouracil in pigs: a new preclinical model. | the goal of this study was to develop an animal model of intestinal injury induced by 5-fluorouracil (5-fu) in pigs. | 2007 | 17785971 |
| adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts. | vascular access dysfunction is a major problem in hemodialysis patients. only 50% of arteriovenous grafts (avgs) will remain patent 1 year after surgery. avgs frequently develop stenoses and occlusions at the venous anastomoses in the venous outflow tract. lumen diameter is not only determined by intimal thickening but is also influenced by remodeling of the vessel wall. vascular remodeling requires degradation and reorganization of the extracellular matrix by the degradation enzymes, matrix met ... | 2007 | 17826244 |
| promoter activity of the long terminal repeats of porcine endogenous retroviruses of the korean domestic pig. | porcine endogenous retroviruses (pervs) in the pig genome represent a potential risk of infection in pig-to-human transplantation and are transmitted vertically. the solitary long terminal repeat (ltr) elements of the pervs affect the replication properties of the individual viruses via their repeat sequences and by encoding a set of specific transcription factors. we examined the promoter activities of solitary ltr elements belonging to the perv-a and -b families of the korean domestic pig (kdp ... | 2007 | 17846510 |
| molecular characterization and temporal expression profiling of presenilins in the developing porcine brain. | the transmembrane presenilin (psen) proteins, psen1 and psen2, have been proposed to be the catalytic components of the gamma-secretase protein complex, which is an intramembranous multimeric protease involved in development, cell regulatory processes, and neurodegeneration in alzheimer's disease. here we describe the sequencing, chromosomal mapping, and polymorphism analysis of psen1 and psen2 in the domestic pig (sus scrofa domesticus). | 2007 | 17854491 |
| ancient dna, pig domestication, and the spread of the neolithic into europe. | the neolithic revolution began 11,000 years ago in the near east and preceded a westward migration into europe of distinctive cultural groups and their agricultural economies, including domesticated animals and plants. despite decades of research, no consensus has emerged about the extent of admixture between the indigenous and exotic populations or the degree to which the appearance of specific components of the "neolithic cultural package" in europe reflects truly independent development. here ... | 2007 | 17855556 |
| effects of epinephrine and vasopressin on cerebral microcirculatory flows during and after cardiopulmonary resuscitation. | both epinephrine and vasopressin increase aortic and carotid arterial pressure when administered during cardiopulmonary resuscitation. however, we recently demonstrated that epinephrine reduces cerebral cortical microcirculatory blood flow. accordingly, we compared the effects of nonadrenergic vasopressin with those of epinephrine on cerebral cortical microvascular flow together with cortical tissue po2 and pco2 as indicators of cortical tissue ischemia. | 2007 | 17855828 |
| efficacy and safety of absorbable metallic stents with adjunct intracoronary beta radiation in porcine coronary arteries. | absorbable metallic stents (ams) utilizing mg alloy carry advantages over permanent metallic stents because of their potential to eliminate stent thrombosis, chronic inflammation, or artifacts with noninvasive imaging. these stents, however, are associated with a modest degree of late recoil and intimal hyperplasia. the aim of the study was to test whether adjunct vascular brachytherapy (vbt) compared to ams alone can overcome these limitations. | 2007 | 17880333 |
| intravenous tezosentan improves gas exchange and hemodynamics in acute lung injury secondary to meconium aspiration. | meconium aspiration induces acute lung injury (ali) and subsequent pulmonary arterial hypertension (pah) which may lead to right ventricular failure. increase of endothelin-1, thromboxane-a, and phosphodiesterases are discussed molecular mechanisms. we investigated the intrapulmonary and hemodynamic effects of the intravenous dual endothelin a and b receptor blocker tezosentan and inhalational iloprost in a model of ali due to meconium aspiration. | 2008 | 17898997 |
| cryopreservation of the germplasm of animals used in biological and medical research: importance, impact, status, and future directions. | molecular genetics and developmental biology have created thousands of new strains of laboratory animals, including rodents, drosophila, and zebrafish. this process will accelerate. a decreasing fraction can be maintained as breeding colonies; hence, the others will be lost irretrievably unless their germplasm can be cryopreserved. because of the increasingly critical role of cryopreservation, and because of wide differences in the success with which various forms of germplasm can be cryopreserv ... | 2008 | 17901073 |
| the pygmy hog is a unique genus: 19th century taxonomists got it right first time round. | the pygmy hog, sus salvanius, the smallest and rarest extant suid was first described as the only member of the genus porcula. it is currently regarded as member of the genus sus and a sister taxon of the domestic pig/eurasian wild boar (sus scrofa). phylogenetic analyses of 2316 bp from three mtdna loci (control-region, cytochrome b, 16s) by bayesian inference and statistical testing of alternative phylogenetic hypotheses all support the original classification of the pygmy hog as a unique genu ... | 2007 | 17905601 |
| validation of two commercial real-time rt-pcr kits for rapid and specific diagnosis of classical swine fever virus. | two real-time rt-pcr kits, developed by lsi (taqvet csf) and adiagene (adiavet csf), obtained an agreement to be commercialised in france, subject to conditions, defined by the french classical swine fever (csf) national reference laboratory. the producers were asked to introduce an internal control to check the rna extraction efficacy. the different criteria assessed were sensitivity, "pestivirus specificity", reproducibility and ease of handling, using 189 different samples. these samples were ... | 2008 | 17913249 |
| fibrinolytic treatment improves the quality of lungs retrieved from non-heart-beating donors. | the use of non-heart-beating donors (nhbds) is an alternative strategy to increase the limited number of donors. the ex vivo evaluation has been proposed to assess the function of the lungs from nhbds as an interim evaluation of the graft before transplantation. we evaluated the effect of a fibrinolytic agent, urokinase, in a pig ex vivo evaluation model. | 2007 | 17919627 |
| angiographic, ultrasonographic, and macroscopic assessment of aortic growth after vcs clips, interrupted polypropylene, or running polyglycolic acid anastomosis. | lack of growth after surgery is still an unsolved issue in growing vessels. aortic surgery is an integral part of vascular pediatric surgery. as an alternative to address this lack of growth in this scenario, we propose the use of titanium clips for vascular anastomosis. | 2007 | 17923198 |
| inhibition of pseudointimal hyperplasia in swine tips models: the efficacy of local delivery of paclitaxel using a perforated balloon catheter. | the aim of this study was to investigate the efficacy and feasibility of local delivery of paclitaxel to inhibit pseudointimal hyperplasia/intimal hyperplasia in swine transjugular intrahepatic portosystemic shunt (tips) models tips were created in seven healthy domestic swine (15-20 kg). before tips stent insertion, we performed a short-term infusion of paclitaxel (treatment group: n = 4) and saline (control group: n = 3) into the tips tract using a balloon catheter in which two 0.010 inch hole ... | 2007 | 17928498 |
| immunity against ns3 protein of classical swine fever virus does not protect against lethal challenge infection. | classical swine fever is a highly contagious disease of swine caused by classical swine fever virus, an oie list a pathogen. in the european union the virus has been eradicated from the domestic pig population and prophylactic immunization has been banned. nevertheless, intervention immunizations using marker vaccines are one possibility to deal with reintroduced csfv. at present, baculovirus-expressed e2 protein is used as such a marker vaccine. however, this vaccine cannot fully protect agains ... | 2007 | 17931119 |
| use of a chitosan-based hemostatic dressing in laparoscopic partial nephrectomy. | an external chitosan-based hemostatic bandage has been used to control aggressive bleeding from traumatic injuries. this study was to evaluate the feasibility of using an internal chitosan dressing based on the external platform to control hemorrhage and urinary leakage by sealing off the parenchymal wound following laparoscopic partial nephrectomy (lpn) in a porcine model. | 2008 | 17932955 |
| the wild boar (sus scrofa) lymphocyte function-associated antigen-1 (cd11a/cd18) receptor: cdna sequencing, structure analysis and comparison with homologues. | the most predominant beta2-integrin lymphocyte function-associated antigen-1 (lfa-1, cd11a/cd18, alphalbeta2), expressed on all leukocytes, is essential for many adhesive functions of the immune system. interestingly, rtx toxin-producing bacteria specifically target this leukocyte beta2-integrin which exacerbates lesions and disease development. | 2007 | 17937788 |
| less smoke and minimal tissue carbonization using a thulium laser for laparoscopic partial nephrectomy without hilar clamping in a porcine model. | we evaluated the utility of a thulium laser and a novel implementation of its use for laparoscopic partial nephrectomy to achieve precise, smokeless, and hemostatic dissection without hilar clamping and with minimal charring in a porcine model. | 2007 | 17941795 |
| use of concentrated human albumin with argon-beam coagulation in laparoscopic partial nephrectomy. | laparoscopic partial nephrectomy (lpn) remains a technically challenging procedure mainly because of the lack of reliable methods of hemostasis. we evaluated the feasibility of using concentrated human albumin with argon-beam coagulation to control hemorrhaging and urinary leakage during lpn. | 2007 | 17941797 |
| zoniporide preserves left ventricular compliance during ventricular fibrillation and minimizes postresuscitation myocardial dysfunction through benefits on energy metabolism. | to investigate whether sodium-hydrogen exchanger isoform-1 (nhe-1) inhibition attenuates myocardial injury during resuscitation from ventricular fibrillation through effects on energy metabolism, using an open-chest pig model in which coronary perfusion was controlled by extracorporeal circulation. | 2007 | 17944021 |
| [early sibling aggression in mammals and its hormonal correlates]. | early sibling aggression is a widespread phenomenon in birds. ornithologists distinguish species with "obligate" and "facultative" siblicide. sibling aggression was described in some mammal species: the domestic pig (sus scrofa), the spotted hyena (crocuta crocuta), the eurasian lynx (lynx lynx), and the iberian lynx (l. par-dinus). in all of them, sibling aggression corresponds well with the "facultative" siblicide model in birds. sibling aggression was observed at the age of 36-64 days in both ... | 2007 | 17944114 |
| molecular coronary mr imaging of human thrombi using ep-2104r, a fibrin-targeted contrast agent: experimental study in a swine model. | the aim of this study was to investigate the use of a fibrin-specific contrast agent (ep-2104r, epix pharmaceuticals, lexington, massachusetts, usa) for targeted molecular magnetic resonance (mr) imaging of human clot material removed from patients in a model of coronary thrombosis in swine. | 2007 | 17948194 |
| chromosomal instability in afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies. | extant placental mammals are divided into four major clades (laurasiatheria, supraprimates, xenarthra and afrotheria). given that afrotheria is generally thought to root the eutherian tree in phylogenetic analysis of large nuclear gene data sets, the study of the organization of the genomes of afrotherian species provides new insights into the dynamics of mammalian chromosomal evolution. here we test if there are chromosomal bands with a high tendency to break and reorganize in afrotheria, and b ... | 2007 | 17958882 |
| a lightweight, partially absorbable mesh (ultrapro) for endoscopic hernia repair: experimental biocompatibility results obtained with a porcine model. | a meticulous surgical technique, a mesh of adequate dimensions, and use of a mesh with good biocompatibility properties are decisively important for minimizing the development of recurrences after endoscopic hernia repair surgery. mesh "shrinkage" is a function of the mesh's biocompatibility, that is, the properties of the mesh. large-pore, lightweight polypropylene meshes possess the best biocompatibility, and the newly developed meshes meet these requirements. | 2008 | 17963002 |
| indomethacin decreases optic nerve oxygen tension by a mechanism other than cyclo-oxygenase inhibition. | we investigated the effect of several non-steroidal anti-inflammatory drugs (nsaids), on the preoptic nerve oxygen tension (onpo2), as indomethacin previously has demonstrated a strong decreasing effect on onpo2. we tested whether these nsaids, like indomethacin, also reduce the increasing effect of dorzolamide on onpo2. | 2008 | 17965100 |
| [transmission of agents of the porcine respiratory disease complex (prdc) between swine herds: a review. part 2--pathogen transmission via semen, air and living/nonliving vectors]. | the transmission of prdc-pathogens (prrsv, influenza virus a, pcv2, m. hyopneumoniae, a. pleuropneumoniae) between swine herds, which was summarized in the first part of the review, mainly occurs via pig movement. the risk of pathogen transmission by insemination with contaminated semen plays only a relevant role in the infection with prrsv and pcv2. a risk of the aerogen transmission of pathogens between herds within a distance of 2 to 3 km is described for m. hyopneumoniae and prrsv. evidence ... | 2007 | 17970334 |
| composition of intestinal enterobacteriaceae populations of healthy domestic pigs. | in this study, the enterobacteriaceae microbiota, including their diversity as well as the distribution of haemolytic and virulence gene-harbouring escherichia coli of 56-day-old healthy piglets, was characterized. both the composition and the diversity of enterobacteriaceae populations varied considerably between individual pigs and intestinal sections. e. coli, enterobacter cloacae, citrobacter freundii and klebsiella pneumoniae dominated the enterobacteriaceae microbiota. however, mucosa-asso ... | 2007 | 17975092 |
| signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity. | cytokines play a pivotal role in allergy development through activating signaling mechanisms, such as the janus kinase/signal transducer and activator of transcription (stat) pathway, which controls the expression of numerous proinflammatory genes. | 2008 | 17981315 |
| value of skin punch biopsies for the diagnosis of acute classical swine fever. | the objective of this study was to determine if skin punch biopsies are appropriate for the diagnosis of classical swine fever. for this purpose, 6 wild boars and 2 domestic pigs were experimentally infected with the highly virulent classical swine fever virus (csfv) koslov and 5 domestic pigs with a csfv field isolate (genotype 2.3 uelzen) derived from wild boar. skin biopsy specimens were tested using virus isolation, real-time reverse transcription polymerase chain reaction (rtrt-pcr), and fl ... | 2007 | 17998561 |
| survival of trichinella papuae muscle larvae in a pig carcass maintained under simulated natural conditions in papua new guinea. | in papua new guinea, trichinella papuae, a non-encapsulated species, is circulating among wild and domestic pigs and saltwater crocodiles. since an important phase of the life cycle of nematodes of the genus trichinella is the time of survival of infective larvae in decaying muscle tissues of the hosts, the carcass of a pig, experimentally infected with larvae of t. papuae, was exposed to the environmental conditions of papua new guinea to establish how long these larvae would survive and remain ... | 2007 | 18005466 |
| population phylogenomic analysis of mitochondrial dna in wild boars and domestic pigs revealed multiple domestication events in east asia. | previously reported evidence indicates that pigs were independently domesticated in multiple places throughout the world. however, a detailed picture of the origin and dispersal of domestic pigs in east asia has not yet been reported. | 2007 | 18021448 |
| immunoglobulin light chain (igl) genes in zebrafish: genomic configurations and inversional rearrangements between (v(l)-j(l)-c(l)) gene clusters. | in mammals, immunoglobulin light chain (igl) are localized to two chromosomal regions (designated kappa and lambda). here we report a genome-wide survey of igl genes in the zebrafish revealing (v(l)-j(l)-c(l)) clusters spanning 5 separate chromosomes. to elucidate igl loci present in the zebrafish genome assembly (zv6), conventional sequence similarity searches and a novel scanning approach based on recombination signal sequence (rss) motifs were applied. rt-pcr with zebrafish cdna was used to c ... | 2008 | 18022691 |
| a porcine deep vein thrombosis model for magnetic resonance-guided monitoring of different thrombectomy procedures. | to establish a porcine model of deep iliac vein thrombosis, which allows monitoring of thrombectomy and thrombolytic procedures by magnetic resonance imaging (mri). | 2007 | 18030194 |
| assessment of global left and right ventricular function using dual-source computed tomography (dsct) in comparison to mri: an experimental study in a porcine model. | we sought to evaluate the ability of retrospectively ecg-gated dual-source computed tomography (dsct) to assess left (lv) and right ventricular (rv) functional parameters in comparison to 1.5 t magnetic resonance imaging (mri). | 2007 | 18030198 |
| the sarcocystis-cyst containing beef and pork as the sources of natural intestinal sarcocystosis in thai people. | human intestinal sarcocystosis is a zoonotic disease caused by two coccidians, i.e. sarcocystis fusiformis (syn. s. bovihominis, s. hominis) due to consumption of raw infected beef and sarcocystis meischeriana (syn. s. suihominis) due to consumption of infected raw pork. in 1987, survey of the macroscopic s. fusiformis cysts in market beef mainly from old water buffalos aged more than 15 years were commonly observed in bangkok. in 2005, the macroscopic cyst was no longer seen in beef of cattle a ... | 2007 | 18041433 |
| interstitial laser ablation of the kidney: acute and chronic porcine study using new-generation diffuser tip fiber. | many ablative techniques have been described for treatment of small renal tumors. we investigated interstitial laser ablation (ila) of porcine kidneys with a new-generation diffuser tip fiber. | 2007 | 18042035 |
| radiofrequency hepatic ablation with internally cooled electrodes and hybrid applicators with distant saline infusion using an in vivo porcine model. | radiofrequency ablation (rfa) of tumors by means of internally cooled (ice) or multitined expandable electrodes combined with infusion of saline into the tissue may improve results. our aim was to determine the efficacy of a previously optimized hybrid ice system (ice combined with infusion of saline into the tissue at a distance of 2mm) in comparison with a conventional ice cluster electrode in porcine liver in vivo. | 2008 | 18042500 |
| the morphology of the inner ear from the domestic pig (sus scrofa). | the morphology of the hair cells of the inner ear end organs from the domestic pig (sus scrofa) have been studied using a combination of scanning and transmission electron microscopy (sem and tem), revealing hair cells from the cochlea and vestibule using a novel surgical and technical approach. this is the first time that the inner ear hair cells from s. scrofa have been studied, thus providing useful anatomical information on the morphology of the hair cells from the cochlea, saccule and utric ... | 2007 | 18045329 |
| efficacy and safety of pimecrolimus-eluting stents in porcine coronary arteries. | we aimed to evaluate an effective dosage and safety profile of pimecrolimus as an anti-inflammatory drug for drug-eluting stents. | 2007 | 18053948 |
| topography of the porcine epicardiac nerve plexus as revealed by histochemistry for acetylcholinesterase. | the aim of the present study was to map the topography of the porcine epicardiac nerve plexus (enp) and to re-examine the total number and distribution of the porcine intracardiac ganglia and neurons. eleven juvenile pigs (sus scrofa domestica, 3-4 weeks of age) were examined employing histochemistry for acetylcholinesterase to reveal the enp on total hearts. the nerves entered porcine epicardium at five sites: (1) ventro-medially to the origin of the superior vena cava, (2) dorsally to the orig ... | 2008 | 18063424 |
| efficacy of lyophilised c-strain vaccine after oral immunisation of domestic pigs and wild boar against classical swine fever: first results. | the aim of this study was to evaluate the efficacy of lyophilised c-strain vaccine in domestic pigs and wild boar after oral application. a new spherical bait form (diameter 3 cm) containing lyophilised vaccine virus and the recent vaccine baits were used for animal experiments. four vaccination groups were established in experiment 1 (group 1: recent liquid bait vaccine; group 2: spherical baits containing one dose of the lyophilised vaccine; groups 3 (domestic pigs) and 4 (wild boar): spherica ... | 2007 | 18077931 |
| epidemiological study of hepatitis e virus infection in european wild boars (sus scrofa) in spain. | evidence of hepatitis e virus (hev) infection in spanish domestic pig has been reported and hence it was advisable to search for this zoonotic pathogen in wild boar populations. a total of 150 wild boar serum samples from eight geographic areas from south-central spain were used to investigate hev infection in european wild boar (sus scrofa) by means of serology and pcr and its distribution by age, region and management system. anti-hev igg, igm and iga were determined by an in-house elisa. the ... | 2008 | 18082340 |
| short-term effects of biocorrodible iron stents in porcine coronary arteries. | biocorrodible iron stents carry the potential to overcome limitations, such as chronic inflammation and premature recoil, posed by biodegradable polymer and magnesium alloy stents. this study aimed to test the safety and efficacy of biocorrodible iron stents in porcine coronary arteries. | 2008 | 18086136 |
| short- and long-term effects of a novel paclitaxel coated stent in the porcine coronary model. | drug eluting stents (des) are unique in allowing sustained release for weeks after a single short intervention. the challenge with des still remaining is the combination of a biocompatible drug-eluting matrix including an antiproliferative drug showing efficacy and safety in restenosis prevention. the aim of the present animal studies was to evaluate the novel paclitaxel coated coroflex. please stent in the porcine coronary model. | 2008 | 18087665 |
| electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation. | newer guidelines address the importance of effective chest compressions, citing evidence that this primary intervention is usually suboptimally performed during cardiopulmonary resuscitation. we therefore sought a readily available option for monitoring the effectiveness of chest compressions, specifically using the electrocardiogram. | 2008 | 18090357 |
| postresuscitation myocardial diastolic dysfunction following prolonged ventricular fibrillation and cardiopulmonary resuscitation. | postresuscitation myocardial dysfunction is one of the leading causes of early death after successful resuscitation from sudden death. however, the diastolic characteristics of postresuscitation myocardial dysfunction are not well defined. we therefore investigated the postresuscitation left ventricular diastolic function following prolonged cardiac arrest and subsequent cardiopulmonary resuscitation. | 2008 | 18090365 |
| effects of ventilation with 100% oxygen during early hyperdynamic porcine fecal peritonitis. | early goal-directed therapy aims at balancing tissue oxygen delivery and demand. hyperoxia (i.e., pure oxygen breathing) has not been studied in this context, since sepsis increases oxygen radical production, which is believed to be directly related to the oxygen tension. on the other hand, oxygen breathing improved survival in various shock models. therefore, we hypothesized that hyperoxia may be beneficial during early septic shock. | 2008 | 18091553 |
| a new device to simplify flexible endoscopic treatment of zenker's diverticulum. | endoscopic treatment of a zenker's diverticulum (zd) is challenged by maintaining a stable position and visual field. an oblique transparent cap and an overtube have been used with success. the porcine hypopharyngeal pouch is similar to a zd. while using the widespread emr device (wemr) in the esophagus, we realized that the design may be advantageous for treatment of a zd. | 2008 | 18155432 |
| laboratory and clinical development of single keyhole umbilical nephrectomy. | to describe our initial experience with single keyhole nephrectomy in a porcine model and in human subjects. | 2007 | 18158008 |
| detection and surveillance for animal trichinellosis in gb. | the zoonotic disease trichinellosis is considered one of the re-emerging diseases with surveillance and control methods constantly gaining more importance worldwide. recent change in european union (eu) legislation introduces trichinella-free production, and the possibility of risk-based monitoring for trichinella in pigs. this has increased the role of wildlife surveillance programmes and their impact on protecting human health as well as highlighted the need for harmonised surveillance protoco ... | 2008 | 18160221 |
| variability and action mechanism of a family of anticomplement proteins in ixodes ricinus. | ticks are blood feeding arachnids that characteristically take a long blood meal. they must therefore counteract host defence mechanisms such as hemostasis, inflammation and the immune response. this is achieved by expressing batteries of salivary proteins coded by multigene families. | 2008 | 18167559 |