| characterization of hepatic drug-metabolizing activities of bama miniature pigs (sus scrofa domestica): comparison with human enzyme analogs. | we used various substrates and selective inhibitors of human cytochrome p450 (cyp) isozymes as probes to study the metabolism of liver microsomes from chinese bama miniature pigs. nifedipine oxidation (nod) and testosterone 6beta-hydroxylation (6beta-oht) activities were similar between human liver microsomes and those from bama miniature pigs. however, compared with those from humans, liver microsomes from bama miniature pigs showed decreased phenacetin o-deethylation, coumarin 7-hydroxylation, ... | 2006 | 16941956 |
| bladder augmentation with acellular dermal biomatrix in a diseased animal model. | the use of bowel for bladder augmentation is associated with many complications. we have reported that acellular dermal biomatrix can be used successfully for directing the regeneration of each key bladder wall element in healthy domestic pigs. before proposing that this material should be used in the human setting a final set of experiments using this scaffold to replace diseased bladder wall is necessary. we determined if acellular dermal biomatrix can be used to replace diseased bladder wall. ... | 2006 | 16945628 |
| inhibition of dipeptidyl-peptidase iv does not increase circulating igf-1 concentrations in growing pigs. | the enzyme dipeptidyl peptidase-iv (dpp-iv) inactivates a variety of bioactive peptides, including glucagon-like peptide-1 (glp-1) and growth hormone releasing hormone (ghrh). inhibiting dpp-iv in order to increase circulating glp-1 is of interest as a treatment for type ii diabetes. inactivation of dpp-iv may also increase circulating ghrh, potentially enhancing growth in domestic animals. to test the hypothesis that inhibition of dpp-iv activity will influence the growth hormone/ igf-1 axis, g ... | 2006 | 16946406 |
| torque teno virus (ttv) is highly prevalent in the european wild boar (sus scrofa). | the present study represents the first survey of torque teno virus (ttv) prevalence in european wild boar (sus scrofa). the prevalence of two distinct ttv genogroups in 178 spanish wild boar sera from different geographic regions, management conditions, gender and age was determined by a nested pcr method. the overall prevalence of ttv genogroups was 84% (58% for genogroup 1 and 66% for genogroup 2), and differences between genogroup prevalence were observed depending on the geographical region ... | 2006 | 16959441 |
| season controlled reproduction of undomesticated animals. | the following article is a summary of research on the influence of season on the reproductive processes in undomesticated animals. the results presented below show: a/ an annual hormonal profile of domestic pig and wild boar crossbreed and the antioxidant blood system in the different seasons, b/ the possibility of gonadptropic hormone stimulation in chinchillas which are in diestrus or infertile, c/ the possibility of using bison's semen (collected post mortem from the epididymis) for cryoconse ... | 2006 | 16967095 |
| safety and efficacy of bioabsorbable magnesium alloy stents in porcine coronary arteries. | we aimed to determine the safety and efficacy of biobasorbable magnesium alloy stents in porcine coronary arteries. bioabsorbable magnesium stents carry the potential to overcome the limitations posed by permanent metallic stents such as chronic inflammation, late stent thrombosis, prolonged antiplatelet therapy, and artifacts when imaged by multislice-computed tomography or magnetic resonance imaging. | 2006 | 16969879 |
| population structure in ascaris suum (nematoda) among domestic swine in denmark as measured by whole genome dna fingerprinting. | we here analyze the population structure in the pig roundworm, ascaris suum, among domestic pigs in denmark using a whole-genome dna fingerprinting technique, "amplified fragment length polymorphism" (aflp) analysis. with these data, we can extract absolute gene frequency variance components and g-statistics for 135 independent nucleotide polymorphisms. the average proportion of total variance partitioned between jutland and zealand is less than 3% of the total variance, implying no restriction ... | 2005 | 16970605 |
| mitochondrial haplotypes of european wild boars with 2n = 36 are closely related to those of european domestic pigs with 2n = 38. | wild boars from western europe have a 2n = 36 karyotype, in contrast to a karyotype of 2n = 38 in wild boars from central europe and asia and in all domestic pigs. the phylogenetic status of this wild boar population is unclear, and it is not known if it has contributed to pig domestication. we have now sequenced the mtdna control region from 30 european wild boars (22 with a confirmed 2n = 36 karyotype) and six asian wild boars (two hainan and four dongbei wild boars) to address this question. ... | 2006 | 16978174 |
| the responses of growing pigs to a chronic-intermittent stress treatment. | many of the stressor treatments used in animal models of depression have parallels in the normal experiences of domestic pigs. the experiment described here aimed to assess whether a chronic-intermittent stress regime caused behavioural or physiological changes, indicative of depression, in domestic pigs. ten juvenile male pigs were exposed to a social and environmental stress regime. over the stressor period, weight gain was significantly lower in test pigs than in control pigs. stress treatmen ... | 2006 | 16982073 |
| tissue anchors for transmural gut-wall apposition. | with the development of notes (natural orifice transluminal endoscopic surgery) and efforts to advance gastric reduction surgery, alternatives for robust tissue apposition apart from suturing and current mucosal clipping devices may be valuable. | 2006 | 16996353 |
| burn depths evaluation based on active dynamic ir thermal imaging--a preliminary study. | proper diagnostic assessment of burn wound depth is of the highest importance in selecting the mode of burn wound treatment. several diagnostic methods--clinical and histopathological evaluation, as well as methods employing ir imaging--static thermography and active dynamic thermography (adt)--are compared on the basis of in vivo experiments conducted on three domestic pigs (23 burn wounds). adt is presented here as a new, reliable and quantitative method of assessing burn wound depth on the ba ... | 2006 | 16997482 |
| current trends in safety assurance for tissue grafts used in burn treatment. | the author presents a summary of current safety standards for allogeneic and xenogeneic biological skin grafts. the fundamental document relevant to allogeneic transplants, establishing the minimal level of safety guaranteed in european union states, is the european parliament and council directive (2004/23/ec) from march 31st 2004. this directive determines that grafts will be prepared by a licensed or accredited tissue bank, and that this arrangement must be put in place by the member states w ... | 2006 | 16999268 |
| efficacy and safety of right and left atrial ablations on the beating heart with irrigated bipolar radiofrequency energy: a long-term animal study. | the cox maze procedure is the most effective surgical treatment for atrial fibrillation; however, its complexity has limited its clinical utility. the purpose of this study was to simplify the procedure by using an irrigated bipolar radiofrequency ablation device on the beating heart without cardiopulmonary bypass. | 2006 | 17000297 |
| molecular identification of trichuris vulpis and trichuris suis isolated from different hosts. | trichuris suis was isolated from the cecum of two different hosts (sus scrofa domestica -- swine and sus scrofa scrofa -- wild boar) and trichuris vulpis from dogs in sevilla, spain. genomic dna was isolated and internal transcribed spacers (its)1-5.8s-its2 segment from the ribosomal dna (rdna) was amplified and sequenced using polymerase chain reaction techniques. the sequence of t. suis from both hosts was 1,396 bp in length while that of t. vulpis was 1,044 bp. its1 of both populations isolat ... | 2007 | 17004099 |
| in vitro development of cloned embryos derived from miniature pig somatic cells after activation by ultrasound stimulation. | the present study was carried out to examine the activation and development of cloned embryos produced by transferring miniature pig somatic cells into enucleated farm pig oocytes after exposing to ultrasound. the rates of the pronucleus-like structure formation and polar body-like structure extrusion in embryos exposed to ultrasound did not differ from those applied electric pulses. although there was no significant difference in the blastocyst formation rates between different activation metho ... | 2006 | 17009892 |
| molecular epidemiology of trichinella spp. in three baltic countries: lithuania, latvia, and estonia. | meat of domestic pigs and wild boars has been the significant source of emerged human trichinellosis in lithuania, latvia, and estonia over the past two decades. however, there is very little known on the occurrence of trichinella spp. in main wildlife reservoirs and its transmission in domestic and sylvatic cycles in these countries. the present study demonstrated considerably higher endemicity of trichinella spp. in main sylvatic reservoirs (28.9-42% in foxes (vulpes vulpes) and raccoon dogs ( ... | 2007 | 17013647 |
| parenteral vaccination of domestic pigs with brucella abortus strain rb51. | to determine the immunogenicity and efficacy of brucella abortus strain rb51 (srb51) as a vaccine in domestic pigs. | 2006 | 17014337 |
| evaluation of baculovirus-derived recombinant 53-kda protein of trichinella spiralis for detection of trichinella-specific antibodies in domestic pigs by elisa. | the complete gene encoding the 53-kda protein derived from trichinella spiralis was cloned and expressed using a baculovirus-based system. characterization of a purified fusion protein consisting of the 53-kda protein and the glutathione s-transferase protein showed unspecific reactivity with swine pre-immune serum in both enzyme-linked immunosorbent assay (elisa) and western blot analysis. subsequently, a purified c-terminal 6xhis-tagged 53-kda protein was used in an elisa. the evaluation of th ... | 2007 | 17016726 |
| modification of the arterial anastomotic technique improves survival in porcine single lung transplant model. | lung transplantation is a valuable therapeutic option for selected patients with end-stage pulmonary disease. however, this treatment is complicated by ischaemia-reperfusion injury (iri) of the lung in 10-20% of the recipients. we developed an unilateral porcine lung transplant model to study iri and describe our experience with two different arterial anastomotic techniques. | 2006 | 17017708 |
| [methods for investigating trichinella infections in domestic and wild animals]. | trichinellosis is an important parasitic zoonosis that is caused by the intracellular nematode trichinella spp.. infection of humans occurs through consumption of raw (or undercooked) meat containing infectious larvae. in europe, meat from pork, horse, and wild boar have been identified as most important sources of trichinella infections in humans. in switzerland, both the domestic pig and wild boar population are considered free of trichinella. conversely, swiss foxes, lynxs and recently a wolf ... | 2006 | 17024975 |
| nutrient losses from manure and fertilizer applications as impacted by time to first runoff event. | nutrient losses to surface waters following fertilization contribute to eutrophication. this study was conducted to compare the impacts of fertilization with inorganic fertilizer, swine (sus scrofa domesticus) manure or poultry (gallus domesticus) litter on runoff water quality, and how the duration between application and the first runoff event affects resulting water quality. fertilizers were applied at 35 kg p ha-1, and the duration between application and the first runoff event varied betwee ... | 2007 | 17029684 |
| the effect of pedicle expansion on pedicle morphology and biomechanical stability in the immature porcine spine. | biomechanical study in an animal model. | 2006 | 17047529 |
| temporary coronary artery occlusion during off-pump coronary artery bypass grafting with the new poloxamer p407 does not cause endothelial dysfunction in epicardial coronary arteries. | the aim of this study was to assess the efficacy of the novel reversible thermosensitive gel poloxamer 407 for occlusion of the coronary vessel necessary for minimally invasive operations and its effects on coronary endothelium. | 2006 | 17059936 |
| magnetic resonance imaging of the harderian gland in piglets. | the main purpose of the present study was to investigate the value and effectiveness of functional and morphological magnetic resonance imaging (mri), in order to assess the extent of brain injury in a hypoxic-ischaemic piglet model, and further to validate that the ischaemic injury was successfully induced. in this way, we also characterized the harderian gland. mri was performed at 1.5 t in anaesthetized piglets (n = 10, 12-36 h of age). magnetic resonance perfusion and diffusion imaging were ... | 2006 | 17062026 |
| changes in endocrine and neurochemical profiles in neonatal pigs prenatally exposed to increased maternal cortisol. | early life environmental factors are able to influence prenatal development and may cause structural and functional effects on hypothalamic-pituitary-adrenal (hpa) axis and neurotransmitter systems in the offspring. these effects seem to be species specific and may depend on the period of gestation when the factors are effective. elevated maternal cortisol levels are assumed to play a crucial role as a programming factor during prenatal development. thus, the present study was performed in order ... | 2006 | 17065404 |
| effect of hypercapnia on cerebral blood flow and blood volume in pigs studied by positron emission tomography. | pigs are increasingly used as in vivo models in neuroscience, including studies using positron emission tomography. during anesthesia, cerebral blood flow (cbf) and cerebral blood volume (cbv) are mainly regulated by the partial pressure of co2 (pco2) in arterial blood. we sought to determine the effects of increased arterial pco2 (hypercapnia) on cbf and cbv in anesthetized domestic pigs. we anesthetized 4 pigs and manipulated the tidal volume of the ventilator to different pco2 levels. baselin ... | 2006 | 17069026 |
| the effects of ropivacaine at clinically relevant doses on myocardial ischemia in pigs. | a major risk associated with bupivacaine during myocardial ischemia is ventricular fibrillation. we investigated the influence of ropivacaine on cardiac contractility and the propensity to ventricular fibrillation before and after myocardial ischemia in a placebo-controlled pig study. anesthetized domestic pigs were administered 1 mg.kg(-1) of ropivacaine intravenously over 1 min and then 0.03 mg.kg(-1).min(-1) as a 30-min infusion, or saline. the following endpoints were measured before and aft ... | 2006 | 17072705 |
| a paleolithic diet confers higher insulin sensitivity, lower c-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs. | a paleolithic diet has been suggested to be more in concordance with human evolutionary legacy than a cereal based diet. this might explain the lower incidence among hunter-gatherers of diseases of affluence such as type 2 diabetes, obesity and cardiovascular disease. the aim of this study was to experimentally study the long-term effect of a paleolithic diet on risk factors for these diseases in domestic pigs. we examined glucose tolerance, post-challenge insulin response, plasma c-reactive pro ... | 2006 | 17081292 |
| prevalence of streptococcus suis genotypes in wild boars of northwestern germany. | invasive serotype 2 (cps2+) strains of streptococcus suis cause meningitis in pigs and humans. four case reports of s. suis meningitis in hunters suggest transmission of s. suis through the butchering of wild boars. therefore, the objective of this study was to investigate the prevalence of potentially human-pathogenic s. suis strains in wild boars. s. suis was isolated from 92% of all tested tonsils (n=200) from wild boars. a total of 244 s. suis isolates were genotyped using pcr assays for the ... | 2007 | 17085699 |
| noninfectious complications due to vascular access ports (vaps) in yucatan minipigs (sus scrofa domestica). | vascular access ports (vaps) for studies requiring intermittent or continuous infusion and frequent sampling are well accepted and widely used in large animal species. however, the use of medical devices such as vaps to facilitate sample collection can lead to complications. noninfectious complications of vap implantation can result from thrombotic or mechanical obstructions, other mechanical problems, and animal-associated complications. to facilitate our research, we surgically implanted vaps ... | 2006 | 17089988 |
| the use of a micro-bubble contrast agent to allow visualization of the biliary tree. | micro-bubble contrast agents have been used as contrast agents in the vascular system to allow visualization of blood flow by ultrasound. we examined the use of this type of contrast agent for visualization of bile duct by ultrasound. a laparotomy was performed on a domestic farm pig and the common bile duct was cannulated with a 20 gauge catheter. the contrast agent, perflutren lipid microspheres (definity), was injected in different dilutions. sonographic images were obtained by scanning direc ... | 2006 | 17100724 |
| bilateral intra-annular spinal compressive stresses in vivo. | the purpose of this pilot study was to determine if compressive stresses in the annulus of the intervertebral disc vary with activity in a quadruped and are affected by treatment with an implant. pilot in vivo tests were conducted on skeletally immature domestic pigs (approved by iacuc). one pair of sensors was implanted within the annulus of t10-11, and the second pair at t8-9. a staple was them implanted across the right side of t8-9. wires were routed subcutaneously and exited at the dorsal c ... | 2006 | 17108458 |
| [the histogenesis of interrenal primordium of the adrenal gland in pig (sus domestica)]. | using light, electron microscopy and cytochemistry, the early (embryonic week 4-8) stages of adrenal gland (ag) development were studied in domestic pig. the interrelations between the cells of the fetal cortex (fc) and chromaffin cells (cc) were traced. at week 5, ag primordium is represented by fc, which consists of the epithelioid cells, with the ingrowing neural cords containing cc islets. starting at the early embryonic period and up to fetal period, cc and interrenal cells of fc are closel ... | 2006 | 17111663 |
| analysis of expressed sequence tags from skeletal muscle-specific cdna library of chinese native xiang pig. | a longissimus dorsi muscle cdna library of xiang pig was constructed, and 131 randomly isolated clones were sequenced in this study. the results of bioinformatics analysis showed that 131 ests represented 109 unique clones sequences, of which 99 showed homology to previously identified genes in humans or other mammals, 3 matched other uncharacterized expressed sequence tags (ests), and 7 showed no significant matches to sequences already present in dna databases. no protein matches were found fo ... | 2006 | 17112969 |
| intrathoracic pressure regulation for intracranial pressure management in normovolemic and hypovolemic pigs. | to evaluate the potential to use subatmospheric intrathoracic pressure to regulate intracranial pressure (icp) in normovolemic and hypovolemic animals, we tested the hypothesis that mechanical devices designed to reduce intrathoracic pressure will decrease icp in a dose-related manner. an inspiratory impedance threshold device was used in spontaneously breathing animals and an intrathoracic pressure regulator was attached to a positive pressure ventilator and used in apneic animals: both devices ... | 2006 | 17114984 |
| a one-step, gel-based rt-pcr assay with comparable performance to real-time rt-pcr for detection of classical swine fever virus. | classical swine fever, a notifiable disease to the office international des epizooties (oie), is a highly contagious viral disease affecting both domestic pigs and wild boars. rapid, sensitive, and specific detection of the causing agent classical swine fever virus (csfv) is therefore essential for diagnosis and control of the disease. most protocols for gel-based pcr consist of two steps, reverse transcription followed by pcr. such a protocol is time consuming, laborious and more prone to conta ... | 2007 | 17123637 |
| systematics and epidemiology of trichinella. | in this review, we describe the current knowledge on the systematics, ecology and epidemiology of trichinella and trichinellosis, and the impact of recent research discoveries on the understanding of this zoonosis. the epidemiology of this zoonosis has experienced important changes over the past two decades, especially with regard to the importance of the sylvatic cycle and the sylvatic species. outbreaks of trichinellosis due to trichinella spiralis from domestic swine, while still frequent, in ... | 2006 | 17134656 |
| a novel method of endoscopic submucosal dissection with blunt abrasion by submucosal injection of sodium carboxymethylcellulose: an animal preliminary study. | endoscopic submucosal dissection (esd), particularly the process of submucosal incision with a knife, is technically difficult and carries a high risk of perforation. submucosal injection of a viscous substance, eg, jelly, obviates the need of submucosal incision with a knife. sodium carboxymethylcellulose (scmc), known as cellulose gum, is highly viscous when dissolved in water. | 2006 | 17140905 |
| pharmacologic manipulation of the porcine ureter: acute impact of topical drugs on ureteral diameter and peristaltic activity. | intraluminal application of pharmacologic agents for acute ureteral dilation may facilitate difficult ureteroscopy. we characterized the in-vivo effects of intraluminal application of verapamil and theophylline on ureteral peristalsis and diameter in a porcine model. | 2006 | 17144869 |
| differential response to transforming growth factors-beta(1) and beta(2): connective tissue deposition in animal models. | the ability of transforming growth factor (tgf)-beta(1) and tgf-beta(2) to promote connective tissue deposition were compared in different animal models. a single subcutaneous injection of tgf-beta(2) in collagen/heparin gel carrier promoted markedly more extensive development of connective tissue than tgf-beta(1) at the site of injection in both neonatal and adult mice. both tgf-beta(1) and tgf-beta(2) promoted deposition of dense and well-vascularized connective tissue matrix infiltrated with ... | 1995 | 17147660 |
| chinese white rongchang pig does not have the dominant white allele of kit but has the dominant black allele of mc1r. | the mast/stem cell growth factor receptor (kit) and melanocortin receptor 1 (mc1r) mutations are responsible for coat color phenotypes in domestic pigs. rongchang is a chinese indigenous pig breed with a white coat color phenotype. to investigate the genetic variability of the kit and mc1r genes and their possible association with the coat color phenotype in this breed, a gene duplication and splice mutation of kit were diagnosed in a sample of 93 unrelated rongchang animals. the results show th ... | 2007 | 17150979 |
| porcine circovirus type 2 antibody detection in backyard pigs from mexico city. | pcv2 antibodies have been found in pigs from all continents. however, this finding has been mainly studied in domestic swine reared under intensive production conditions. mexico city, with a human population over 19 million in 2005, has both urban and rural areas. the pig production in its rural area is based on small family backyard farms. taking into account this rather unique form of rearing pigs, the objective of this study was to determine the seroprevalence in backyard pigs from the rural ... | 2007 | 17157886 |
| real-time detection and alerting for acute st-segment elevation myocardial ischemia using an implantable, high-fidelity, intracardiac electrogram monitoring system with long-range telemetry in an ambulatory porcine model. | the purpose of this study was to evaluate feasibility of using real-time, high-fidelity, intracardiac electrogram monitoring from a permanently implantable ischemia detection system (iids), with long-range telemetry capability to detect st-segment shifts associated with acute or subacute coronary occlusion in a porcine model. | 2006 | 17161264 |
| laparoscopic ice slurry coolant for renal hypothermia. | we assessed the safety and efficacy of microparticulate ice slurry for laparoscopic hypothermia during renal ischemia in a single kidney porcine model. | 2007 | 17162095 |
| different fecal shedding patterns of two common strains of hepatitis e virus at three japanese swine farms. | zoonotic infections caused by eating the meat of deer, wild boar, and pig have been suggested in japan, a country that is not epidemic for hepatitis e caused by hepatitis e virus (hev). this virus is widely spread in domestic pigs in both epidemic and non-epidemic countries. we studied fecal hev shedding patterns on three japanese farms that had two common genotype iii hev strains. two of the three farms had high shedding peaks (75% and 100%) in pigs 1-3 months of age, suggesting that these anim ... | 2006 | 17172388 |
| implant-supported prosthetic applications upon development of children and adolescents: a pilot study in pigs. | the purpose of this study is the investigation of the application of implant-supported prosthetic restorations using 2 implants supporting a fixed prosthesis during the physical growth and the development period of growing pigs. | 2006 | 17172960 |
| patent foramen ovale: standards for a preclinical model of prevalence, structure, and histopathologic comparability to human hearts. | this study evaluated and standardized a patent foramen ovale (pfo) preclinical model in gross anatomic and histopathologic features. | 2007 | 17173313 |
| genetic characterisation of african swine fever viruses from outbreaks in southern africa (1973-1999). | african swine fever (asf) is a highly lethal and economically significant disease of domestic pigs in the southern african sub-region, where outbreaks regularly occur. there is anecdotal evidence suggesting that trans-boundary movement of infected animals may have played a role in precipitating widespread outbreaks in the past, however, since the 1970s outbreaks have generally been more localised, particularly in those countries where control of animal movement is strictly regulated. the origin ... | 2007 | 17174485 |
| differential expression of platelet-derived growth factor receptors in porcine fibroblasts cultured from skin and granulation tissue. | this study investigated the biological response of fibroblasts cultured from uninjured skin and granulation tissue from different stages of healing wounds to the three isoforms of platelet-derived growth factor. fibroblasts were derived by explant culture from the skin or the granulation tissue that formed within open mesh nylon schilling-hunt chambers (postoperative days 10, 20, 30, and 50) which had been implanted subcutaneously in the backs of domestic pigs. cells were cultured under identica ... | 1996 | 17177826 |
| enteric caliciviruses in domestic pigs in hungary. | caliciviruses closely related to human norovirus and sapovirus were recently detected in domestic pigs, causing discussions about the animal reservoir and the potential for zoonotic transmission to humans. to detect porcine caliciviruses, 17 fecal samples collected on two swine farms in southwestern hungary were tested by reverse transcription-polymerase chain reaction. three (17.6%) samples were positive for caliciviruses. this study confirms the presence of caliciviruses, both porcine sapoviru ... | 2007 | 17180626 |
| a history of normal plates, tables and stages in vertebrate embryology. | developmental biology is today unimaginable without the normal stages that define standard divisions of development. this history of normal stages, and the related normal plates and normal tables, shows how these standards have shaped and been shaped by disciplinary change in vertebrate embryology. the article highlights the normal plates of the development of the vertebrates edited by the german anatomist franz keibel (16 volumes, 1897-1938). these were a major response to problems in the relat ... | 2007 | 17183461 |
| genetic diversity in wild (sus scrofa scrofa) and domestic (sus scrofa domestica) pigs and their hybrids based on polymorphism of a fragment of the d-loop region in the mitochondrial dna. | we examined the variation in mitochondrial dna by sequencing the d-loop region in wild and domestic (large-white breed) pigs, in hybrids between domestic and wild pigs, and in monteiro pigs. a d-loop fragment of approximately 330 bp was amplified by pcr. sequencing of dna amplicons identified haplotypes previously described as european and asian types. monteiro pigs and wild pigs had european haplotypes and domestic pigs had both european and asian haplotypes. | 2006 | 17183469 |
| running speed in mammals increases with muscle n-6 polyunsaturated fatty acid content. | polyunsaturated fatty acids (pufas) are important dietary components that mammals cannot synthesize de novo. beneficial effects of pufas, in particular of the n-3 class, for certain aspects of animal and human health (e.g., cardiovascular function) are well known. several observations suggest, however, that pufas may also affect the performance of skeletal muscles in vertebrates. for instance, it has been shown that experimentally n-6 pufa-enriched diets increase the maximum swimming speed in sa ... | 2006 | 17183696 |
| radiofrequency ablation of normal lungs after pulmonary artery embolization with use of degradable starch microspheres: results in a porcine model. | the present study was performed to evaluate the effect of pulmonary artery embolization on radiofrequency (rf) ablation of normal porcine lungs. | 2006 | 17185698 |
| subretinal posterior pole injury induces selective proliferation of rpe cells in the periphery in in vivo studies in pigs. | to study topographical differences in porcine retinal pigment epithelial (rpe) cell proliferation (1) in vivo, after experimental central surgical subretinal injury, and (2) in vitro. | 2007 | 17197554 |
| evaluation of microporous polysaccharide hemospheres for parenchymal hemostasis during laparoscopic partial nephrectomy in the porcine model. | we evaluated the efficacy of microporous polysaccharide hemospheres (mph) for parenchymal hemostasis during laparoscopic partial nephrectomy (lpn) in the porcine model. | 2006 | 17212884 |
| acetylcholine injection into the amygdala elicits vocalization in domestic pigs (sus scrofa). | in a pilot study we have injected the amygdala of five female pigs (age 8 weeks) with acetylcholine (ach, 5.5mum/20mul) and recorded short latency utterances. the evoked vocalizations displayed the characteristics of natural screams in sonagram appearance and hearing impression. quantitative analyses, too, revealed the similarity of the ach-evoked vocalizations with natural screaming. the results demonstrate for the first time that aversive vocalizations can be triggered by cholinergic amygdala ... | 2007 | 17215052 |
| progenitor cells from the porcine neural retina express photoreceptor markers after transplantation to the subretinal space of allorecipients. | work in rodents has shown that cultured retinal progenitor cells (rpcs) integrate into the degenerating retina, thus suggesting a potential strategy for treatment of similar degenerative conditions in humans. to demonstrate the relevance of the rodent work to large animals, we derived progenitor cells from the neural retina of the domestic pig and transplanted them to the laser-injured retina of allorecipients. prior to grafting, immunocytochemical analysis showed that cultured porcine rpcs wide ... | 2007 | 17218397 |
| structure traits of longissimus lumborum muscle in wild boar/domestic pig hybrids. | the structure of musculus longissimus lumborum (m.l.l.) was evaluated with respect to proportion of three muscle fiber types and their diameters, in gilts and barrows of wild boar/domestic pig hybrids. the experiment was carried out on 29 hybrids (21 barrows and 8 gilts) which originated from crossing duroc sows with wild boar (sus scrofa ferus). the diameter of the "red" fibres in barrows was 48.42 microm, significantly greater than in gilts--43.71 microm. the diameters of the remaining two typ ... | 2006 | 17220008 |
| low tube voltage improves computed tomography imaging of delayed myocardial contrast enhancement in an experimental acute myocardial infarction model. | we sought to evaluate the influence of tube voltage on the visualization of acute myocardial infarction (mi) in cardiac multislice spiral computed tomography (msct). | 2007 | 17220730 |
| evaluation of males spermiogram in domestic pigs. | a microscopic assessment was used to estimate sperm morphological structure in 405 ejaculates from 70 boars according to blom classification. the classification of spermiogram quality according to a new 6-degree scale was also established. we found, that male spermiograms in domestic pigs were characterized by a large variability both between and within breeds. the estimation of semen quality, only with regard to the mean frequency of occurrence of particular morphological forms of spermatozoa, ... | 2006 | 17220947 |
| sperm morphology of cattle and domestic pigs. | sperm morphology was evaluated (using blom classification) in 44 ejaculates of 11 bulls and 44 ejaculates of 11 boars. significant differences in sperm morphology were found between bulls and boars. in addition, the correlations between frequency of morphological changes and morphometrical traits of boar spermatozoa were demonstrated. more morphological anomalies of spermatozoa were recorded in ejaculates containing longer spermatozoa. | 2006 | 17220948 |
| analysis of the physical properties of costal cartilage in a porcine model. | to determine the impact of interventions on the degree of warping of costal cartilage. | 2007 | 17224486 |
| abnormal kidneys from the domestic pig (sus scrofa). | | 1894 | 17232112 |
| post-resuscitation haemodynamics in a novel acute myocardial infarction cardiac arrest model in the pig. | although a considerable amount of promising experimental research has been performed on cardiopulmonary resuscitation, clinical data indicate an ongoing limited outcome in human beings. one reason for this discrepancy could be that experimental studies use healthy animals whereas most human beings undergoing cardiopulmonary resuscitation suffer from acute or chronic myocardial dysfunction. to overcome this problem, we sought to develop a new model of myocardial infarction, that is easy to perfor ... | 2007 | 17241498 |
| assessment of acute reperfused myocardial infarction with delayed enhancement 64-mdct. | objective: the purpose of this study was to evaluate the utility of delayed enhancement 64-mdct in the assessment of myocardial infarct size in a porcine model of acute reperfused myocardial infarction. ct can be used for noninvasive assessment of coronary artery stenosis, but to our knowledge, evaluation of myocardial viability in the subacute phase of acute myocardial infarction has not been validated. we performed delayed enhancement imaging on six domestic swine 5 days after reperfused acute ... | 2007 | 17242218 |
| mri-based safety evaluation of the ventrica magnetic coronary anastomotic system. | the ventrica magnetic vascular positioner system is a novel automatic anastomotic coupling device for distal coronary artery anastomosis. there is concern that enormous magnetic fields may negatively affect graft anastomosis or coronary artery blood flow, or that they may lead to disconnection of the magnetic ports. forty-five domestic swine (26.6 +/- 5.9 kg) underwent magnetic resonance imaging after a single ventrica anastomosis of the left internal mammary artery to the left anterior descendi ... | 2007 | 17244918 |
| photoperiod and luteinizing hormone secretion in domestic and wild pigs. | during seasonal anoestrus (long-days), oestradiol can effectively inhibit the pulsatile secretion of luteinizing hormone (lh) in sheep. the aim of our trial was to determine whether the same regulatory mechanism exists in the pig. altogether, 20 ovariectomized and oestradiol-implanted gilts (16 domestic pigs, 4 european wild boars) were randomly allocated to two treatment groups. the first group was kept under a short-day light-dark cycle of 8l:16d, and the second group under a long-day light re ... | 2008 | 17250979 |
| focal epidural cooling reduces the infarction volume of permanent middle cerebral artery occlusion in swine. | the protective effect against ischemic stroke by systemic hypothermia is limited by the cooling rate and it has severe complications. this study was designed to evaluate the effect of sbh induced by epidural cooling on infarction volume in a swine model of pmcao. | 2007 | 17254860 |
| microwave ablation with a single small-gauge triaxial antenna: in vivo porcine liver model. | to evaluate the performance of a 17-gauge triaxial antenna at microwave ablation in an in vivo porcine liver model. | 2007 | 17255414 |
| cp7_e2alf: a safe and efficient marker vaccine strain for oral immunisation of wild boar against classical swine fever virus (csfv). | wild boar are an important reservoir of classical swine fever virus (csfv) in several european countries, where most of the primary outbreaks in domestic pigs are directly related to the endemic disease situation in the wild boar population. oral immunisation has been introduced as an additional control measure to accelerate csf eradication in wild boar in germany since 1993. immunisation with an oral bait vaccine based on the conventionally attenuated live vaccine strain "c" proved to be safe a ... | 2007 | 17257713 |
| evaluation of the mechanical strength and patency of functional end-to-end anastomoses. | although many mechanical devices are being developed for functional end-to-end anastomosis (fetea), the best choice remains to be determined. the mechanical strength of each device is an important factor associated with anastomotic leakage. in turn, anastomotic patency is related to postoperative stenosis. this study examined the bursting pressure and circumference of several feteas. | 2007 | 17285383 |
| removal of necrotic tissue with an ananain-based enzyme-debriding preparation. | an enzymatic debriding preparation was formulated with purified enzyme derived from a crude pineapple stem extract. the primary component of this preparation was the sulfhydryl protease ananain which represented >/=85% of the proteolytic activity. the remaining proteolytic activity in the preparation was contributed by a co-purifying homologous cysteine protease comosain. taken together these two proteases provided a protein purity of greater than 95% as judged by sodium dodecyl sulfate polyacry ... | 1996 | 17309694 |
| biomechanical response of the pediatric abdomen, part 1: development of an experimental model and quantification of structural response to dynamic belt loading. | the abdomen is the second most commonly injured region in children using adult seat belts, but engineers are limited in their efforts to design systems that mitigate these injuries since no current pediatric dummy has the capability to quantify injury risk from loading to the abdomen. this paper develops a porcine (sus scrofa domestica) model of the 6-year-old human's abdomen, and then defines the biomechanical response of this abdominal model. first, a detailed abdominal necropsy study was unde ... | 2006 | 17311157 |
| differential anti-influenza activity among allelic variants at the sus scrofa mx1 locus. | a promising way to oppose infectious challenges would be to improve the resistance of the target species through genetic selection. theoretically, a candidate gene is available against influenza viruses since a resistance trait was fortuitously discovered in the a2g mouse strain. this trait was demonstrated to be correlated with the expression of a specific isoform of the type i interferon (ifn)-dependent protein mx, an isoform coded by a specific allele at the mouse mx1 locus. two allelic polym ... | 2007 | 17316142 |
| bloodless laparoscopic liver resection using radiofrequency thermal energy in the porcine model. | the aim of this study was to assess the feasibility and safety of laparoscopic hepatectomy using radiofrequency (rf) thermal energy in a porcine model. fifteen female domestic pigs weighing 29.3 kg (range 25 to 35 kg) were used. five transversal abdominal incisions (3 of 1 cm and 2 of 0.5 cm) were made for the introduction of the video camera and the other laparoscopic instruments. with the porta hepatis not clamped, the liver was inspected and the preferred lobe each time was divided using rf ( ... | 2007 | 17318049 |
| sero-survey on aino, akabane, chuzan, bovine ephemeral fever and japanese encephalitis virus of cattle and swine in korea. | vector-borne arboviruses produce mild to severe symptoms in domestic animals. bovine ephemeral fever (bef), akabane, aino, and chuzan virus have been primarily attributed to reproductive disorders or febrile diseases in cattle, and japanese encephalitis virus (jev) is mainly associated with reproductive failures in swine. we investigated antibody titers from domestic swine against four bovine arboviruses (bef, akabane, aino, and chuzan virus) and from cattle against jev in korea. while the posit ... | 2007 | 17322773 |
| anesthesia for cardiovascular interventions and magnetic resonance imaging in pigs. | large animal models are still required for many experimental purposes. the aim of the current study was to define a viable narcotic procedure for experimental cardiovascular interventions and imaging in pigs. a total of 32 domestic pigs were used. animals received propofol, midazolam, and fentanyl as continuous intravenous infusion anesthesia for complex vascular interventions, angiographic x-ray imaging, and magnetic resonance imaging (mri). anesthesia was maintained for 6 to 10 h. the initial ... | 2007 | 17343350 |
| phylogeny and ancient dna of sus provides insights into neolithic expansion in island southeast asia and oceania. | human settlement of oceania marked the culmination of a global colonization process that began when humans first left africa at least 90,000 years ago. the precise origins and dispersal routes of the austronesian peoples and the associated lapita culture remain contentious, and numerous disparate models of dispersal (based primarily on linguistic, genetic, and archeological data) have been proposed. here, through the use of mtdna from 781 modern and ancient sus specimens, we provide evidence for ... | 2007 | 17360400 |
| genetic variability and evolution of hepatitis e virus. | hepatitis e virus (hev) is the sole member of the genus hepevirus in the family hepeviridae. hev is transmitted primarily by the fecal-oral route, and water-borne epidemics are characteristic of hepatitis e in many developing countries in asia, africa and latin america where sanitation conditions are suboptimal. accumulating lines of evidence indicate that hev-associated hepatitis also occurs domestically among individuals in industrialized countries, that there are animal reservoirs of hev such ... | 2007 | 17363102 |
| optical coherence tomography: a noninvasive method to assess wound reepithelialization. | accurate assessment of wound healing may require invasive tissue biopsies, limiting its clinical usefulness in humans. optical coherence tomography (oct) is a novel, high-resolution method using light reflection to obtain noninvasive cross sectional imaging of biological tissues. | 2007 | 17363766 |
| skin decontamination of mustards and organophosphates: comparative efficiency of rsdl and fuller's earth in domestic swine. | research in skin decontamination and therapy of chemical warfare agents has been a difficult problem due to the simultaneous requirement of rapid action and non-aggressive behaviour. the aim of this study was to compare the performance of two decontaminating systems: the canadian reactive skin decontaminant lotion (rsdl) and the fuller's earth (fe). the experiment was conducted with domestic swine, as a good model for extrapolation to human skin. rsdl and fe were tested against sulphur mustard ( ... | 2007 | 17370872 |
| microbubbles in the pulmonary artery generated during experimental hepatic radiofrequency ablation is correlated with increased pulmonary arterial pressure. | microbubbles in hepatic veins during hepatic radiofrequency (rf) ablation is a well-known observation. in this experimental study, we examined the association between microbubbles in the pulmonary artery and alterations in mean pulmonary arterial pressure (mpap) during hepatic rf ablation with a perfusion electrode system. | 2007 | 17377191 |
| assessment of the lapraty clip for facilitating reconstructive laparoscopic surgery in a porcine model. | to assess the efficacy, reliability, and performance of the lapraty clip (ltc) as a substitute for knot tying during reconstructive surgery in a porcine model. | 2007 | 17382183 |
| assessment of cu-ets as a pet radiopharmaceutical for evaluation of regional renal perfusion. | the copper(ii) complex of ethylglyoxal bis(thiosemicarbazone) (cu-ets) was evaluated as a positron emission tomography (pet) radiopharmaceutical for assessment of regional renal perfusion. | 2007 | 17383574 |
| advances in swine biomedical model genomics. | this review is a short update on the diversity of swine biomedical models and the importance of genomics in their continued development. the swine has been used as a major mammalian model for human studies because of the similarity in size and physiology, and in organ development and disease progression. the pig model allows for deliberately timed studies, imaging of internal vessels and organs using standard human technologies, and collection of repeated peripheral samples and, at kill, detaile ... | 2007 | 17384736 |
| cardiac effects of endothelin receptor antagonism in endotoxemic pigs. | myocardial depression in sepsis is frequently encountered clinically and contributes to morbidity and mortality. increased plasma levels of endothelin-1 (et-1) have been described in septic shock, and previous reports have shown beneficial effects on cardiovascular performance and survival in septic models using et receptor antagonists. the aim of the current study was to investigate specific cardiac effects of et receptor antagonism in endotoxicosis. sixteen domestic pigs were anesthetized and ... | 2007 | 17400719 |
| preweaning housing effects on behavior and physiological measures in pigs during the suckling and fattening periods. | the effect of the preweaning housing system on the stress response of pigs before weaning and during fattening was studied in 33 litters of domestic pigs. three preweaning housing systems were compared: barren crate (standard farrowing crate without straw), enriched crate (20% larger crate, with straw), and as a control, a farrowing pen (pen, 60% larger than the barren crate, with straw). at 25 d of age, pigs were tested with an isolation test and 1 d later with a human approach test (humant). p ... | 2007 | 17400972 |
| high prevalence of unusual genotypes of toxoplasma gondii infection in pork meat samples from erechim, southern brazil. | toxoplasmosis is the most common cause of infectious uveitis in brazil, with a higher frequency in the south of the country. we have collected samples from porcine tongue and diaphragm obtained in both large and small abattoirs and used molecular biological technique to determine the prevalence of infection and rflp analysis to type the parasites. seventeen out of 50 (34%) samples from the diaphragm and 33 out of 50 (66%) samples from the tongue demonstrated a positive pcr reaction for t. gondii ... | 2007 | 17401480 |
| is all ventricular fibrillation the same? a comparison of ischemically induced with electrically induced ventricular fibrillation in a porcine cardiac arrest and resuscitation model. | the standard porcine cardiac arrest model uses electrical induction of ventricular fibrillation. reported restoration of spontaneous circulation and survival rates in this model are as high as 90% for ventricular fibrillation durations of 7-10 mins, values substantially greater than rates in the clinical population (i.e., 20% to 30%). a high first shock success rate, infrequent refibrillation, and short times for restoration of spontaneous circulation are typical of the model. the purpose of thi ... | 2007 | 17414084 |
| fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (nr6a1). | the number of vertebrae in pigs varies and is associated with meat productivity. wild boars, which are ancestors of domestic pigs, have 19 vertebrae. in comparison, european commercial breeds have 21-23 vertebrae, probably owing to selective breeding for enlargement of body size. we previously identified two quantitative trait loci (qtl) for the number of vertebrae on sus scrofa chromosomes (ssc) 1 and 7. these qtl explained an increase of more than two vertebrae. here, we performed a map-based ... | 2007 | 17416745 |
| a review of viral diseases of the european wild boar: effects of population dynamics and reservoir rôle. | there has been a worldwide increase in the number and geographical spread of wild boar populations in recent decades leading to an increase in both the circulation of disease agents and greater contact with domestic animals and humans. diseases affect the population dynamics of wildlife but the effects of most viral diseases on the european wild boar are largely unknown. many viral diseases present in domestic pig populations are also present in wild boars where they can provide a disease reserv ... | 2008 | 17420149 |
| effects of intraluminal irradiation with holmium-166 for tips stenosis: experimental study in a swine model. | we wanted to evaluate the effectiveness of intraluminal irradiation with holmium-166 ((166)ho) for reducing the pseudointimal hyperplasia (pih) in the transjugular intrahepatic portosystemic shunt (tips) tract in a swine model. | 2007 | 17420630 |
| antioxidant vitamins induce angiogenesis in the normal pig kidney. | the effects of chronic supplementation with antioxidant vitamins on angiogenesis are controversial. the aim of the present study was to evaluate in kidneys of normal pigs the effect of chronic supplementation with vitamins e and c, at doses that are effective in reducing oxidative stress and attenuating angiogenesis under pathological conditions. domestic pigs were randomized to receive a 12-wk normal diet without (n = 6) or with antioxidant vitamins supplementation (1g/day vitamin c, 100 iu.kg( ... | 2007 | 17429028 |
| [wild and domestic animals as permanent trichinella reservoir in poland]. | [corrected] since owen first described trichinella as a human patogen in 1835, the number of organisms comprising this genus has grown dramatically. this etiological agent of human trichinellosis shows worldwide distribution in domestic and/or sylvatic animals. | 2006 | 17432240 |
| an advanced sheep (ovis aries, 2n = 54) cytogenetic map and assignment of 88 new autosomal loci by fluorescence in situ hybridization and r-banding. | presented herein is an updated sheep cytogenetic map that contains 452 loci (291 type i and 161 type ii) assigned to specific chromosome bands or regions on standard r-banded ideograms. this map, which significantly extends our knowledge of the physical organization of the ovine genome, includes new assignments for 88 autosomal loci, including 74 type i loci (known genes) and 14 type ii loci (ssrs/microsatellite marker/stss), by fish-mapping and r-banding. comparison of the ovine map to the catt ... | 2007 | 17433010 |
| [laparoscopic diagnostics of the acute bowel ischemia--first experimental experience]. | aim of the study was to prove possibilities of laparoscopic diagnostics of an acute bowel ischemia when using fluorescein dye and the ultra-violet (uv) light. | 2007 | 17436677 |
| effects of an impedance threshold device on hemodynamics and restoration of spontaneous circulation in prolonged porcine ventricular fibrillation. | an impedance threshold device (itd) has been designed to enhance circulation during cpr by creating a negative intrathoracic pressure during the relaxation phase of chest compression. | 2007 | 17454804 |
| pandemic influenza planning: shouldn't swine and poultry workers be included? | recent research has demonstrated that swine and poultry professionals, especially those who work in large confinement facilities, are at markedly increased risk of zoonotic influenza virus infections. in serving as a bridging population for influenza virus spread between animals and man, these workers may introduce zoonotic influenza virus into their homes and communities as well as expose domestic swine and poultry to human influenza viruses. prolonged and intense occupational exposures of huma ... | 2007 | 17459539 |
| rational intraabdominal pressure monitoring: how to do it? | intraabdominal hypertension (iah) is increasingly appreciated by intensivists as an important cause of organ dysfunction, even at pressure levels which were previously thought to be harmless. therefore, the goal of this review is to describe the different methods commonly used in clinical practice for intraabdominal pressure (iap) measurement, the advised methodology for each measurement method, and finally to give a rational approach for iap monitoring in daily clinical practice. | 2007 | 17469698 |