the expression of sf-1/ad4bp is related to the process of luteinization in the marmoset (callithrix jacchus) ovary. | expression of the nuclear receptor, steroidogenic factor-1 (sf-1/ad4bp), was studied in a primate (marmoset) ovary using immunohistochemical, rt-pcr, and immunoblot techniques. the periovulatory phase was compared with the luteal phase. with pcr we found a marmoset homolog of sf-1/ad4bp to be expressed in ovarian and other steroidogenic tissues. characteristically, the periovulatory ovaries consisted of growing (non-luteinized) small follicles together with large luteinizing follicles and many c ... | 1997 | 9151117 |
hepatic hemosiderosis in common marmosets, callithrix jacchus: effect of diet on incidence and severity. | we examined the effect of dietary iron concentration on the incidence of hepatic hemosiderosis in common marmosets (callithrix jacchus) and assessed the impact of hemosiderosis on animal health. thirteen young adult common marmosets were fed nutritionally balanced natural-ingredient diets formulated to contain either 100 or 500 ppm of iron. six were fed the low-iron and seven received the high-iron diet. baseline blood values and liver iron content were determined for each animal. animals were w ... | 1997 | 9150491 |
competition and chemical communication in wild groups of common marmosets (callithrix jacchus). | | 1997 | 9071391 |
diagnosis and treatment of trichospirura leptostoma infection in common marmosets (callithrix jacchus). | trichospirura leptostoma is a spirurid nematode that inhabits the pancreatic ducts of the common marmoset, callithrix jacchus, and other new world primates. this parasite was diagnosed in members of this species at the marmoset research center in oak ridge, tennessee colony after their importation from multiple colonies outside the united states. animals with few parasites in the pancreas had few tissue changes, whereas those with many parasites had moderate to severe fibrosis replacing exocrine ... | 1997 | 12456185 |
social context affects phee call production by nonreproductive common marmosets (callithrix jacchus). | common marmosets produce two variants of their long call (phee call) in different situations. intergroup calls are produced in territorial situations, and intragroup separation calls are produced by marmosets isolated from group members. marmoset groups frequently include postpubertal, nonreproductive members; their roles in the spontaneous production of territorial vocalizations is unclear. this study analyzed the production of home cage phee calls by nonreproductive, postpubertal marmosets whi ... | 1997 | 9327096 |
interactions between infant growth and survival: evidence for selection on age-specific body weight in captive common marmosets (callithrix jacchus). | the objective of this study is to investigate factors influencing infant survival in captive common marmosets. we investigated the influence of age-specific weight, litter size, caging, and the presence of helpers on survival to 6 months of age in 189 callithrix jacchus infants. infant survival was analyzed using cox proportional hazards regression, and fitness functions were plotted to explore the relationship between survival and growth. results indicate that weights at birth and 120 days sign ... | 1997 | 9261508 |
calbindin immunoreactivity delineates the circadian visual centers of the brain of the common marmoset (callithrix jacchus). | the hypothalamic suprachiasmatic nucleus and the thalamic pregeniculate nucleus (which includes the intergeniculate leaflet) comprise the circadian visual system in the primate brain. in this study, we used intraocular injections of cholera toxin subunit b to identify those nuclei in the common marmoset brain, and demonstrated that calbindin d-28k immunoreactivity apparently labels most neurons in both the suprachiasmatic and pregeniculate nuclei. these data suggest that calbindin d-28k could re ... | 1997 | 9241439 |
the distribution of p75 neurotrophin receptor-immunoreactive cells in the forebrain of the common marmoset (callithrix jacchus). | the distribution of neurones that could be stained immunohistochemically with antibody to the p75 neurotrophin protein was studied in the forebrain of the common marmoset. the p75-immunoreactive forebrain cells appear to correspond to choline acetyltransferase-immunoreactive (i.e., cholinergic) neurones. two populations of cells could be distinguished on the basis of the intensity of p75 immunostaining. moderately stained cells correspond to cholinergic interneurones of the caudate and putamen, ... | 1997 | 9222533 |
brain-stem auditory evoked potentials in the common marmoset (callithrix jacchus). | brain-stem auditory evoked potentials (baeps) were recorded in 10 common marmosets (callithrix jacchus) to investigate the effects of recording electrode configurations, stimulus rate, and stimulus frequency on baep wave forms and peak latencies. tone burst stimulations were used to evaluate the effects of pure tone on baep wave forms. five positive peaks superimposed on positive and negative slow potentials were identified in the baep recorded at the linkage between the vertex and the dorsal ba ... | 1997 | 9076252 |
comparative study on age-dependent development of surface receptors on peripheral blood lymphocytes in children and young nonhuman primates (marmosets). | general conformity was found concerning age-dependent changes in the major subsets (cd4, cd8, cd2, cd20) and the adhesion molecules cd11a and cd29 on peripheral blood lymphocytes in children and young marmosets (callithrix jacchus). differences exist in the expression of the surface receptors cd45ra and cd56. taking the total number of white blood cells into account, an age-related increase in the absolute numbers of peripheral blood lymphocytes was found in marmosets whereas in children, an age ... | 1997 | 9064482 |
familial influences on ovulatory function in common marmosets (callithrix jacchus). | previous studies have indicated that many, but not all, female common marmosets (callithrix jacchus) housed with their natal families undergo social suppression of ovulation. in this study, we further characterized ovulatory activity in common marmoset daughters to determine the prevalence of social suppression of ovulation and to elucidate familial influences on daughters' ovarian activity. blood samples were collected twice weekly from each of 46 daughters for 5-12 months, usually beginning wh ... | 1997 | 9057963 |
location and developmental regulation of androgen receptor in primate ovary. | locally produced androgens act via granulosa cell androgen receptors to modulate follicular responsiveness to gonadotrophins and thereby contribute to the paracrine regulation of ovarian function. we used quantitative androgen receptor immunocytochemistry to assess androgen receptor distribution in relation to pre-ovulatory follicular development in the common marmoset (callithrix jacchus), a new world primate that ovulates two to four follicles in each approximately 28 day ovarian cycle. ovarie ... | 1997 | 9043913 |
cardiac-like musculature of the intrapulmonary venous wall of the long-clawed shrew (sorex unguiculatus), common tree shrew (tupaia glis) and common marmoset (callithrix jacchus). | the cardiac-like musculature is distributed not only in the heart wall but also in the intrapulmonary venous wall in a few species of insectivores. it has been suggested that the evolutionary origin of venous cardiac-like musculature may be traceable to a basic stock of certain mammalian lines of descent. so, it is important to clarify whether the musculature may be a common structure in lower mammals from insectivores to primates and to examine the functional significance of the structure. | 1997 | 8986302 |
clinical pathologic changes in two marmosets with wasting syndrome. | two sexually mature marmosets (callithrix jacchus) showing clinical signs similar to those seen in wasting marmoset syndrome (weight loss, decreased muscle mass, and alopecia) were evaluated for clinical and anatomic pathologic changes. the most prominent clinical pathologic alterations included macrocytic normochromic anemia, hypoproteinemia, hypoalbuminemia, elevated serum aspartate aminotransferase and alkaline phosphatase levels, and previously unreported changes of thrombocytosis. the princ ... | 2017 | 8994297 |
the effects of cage size and complexity on the behaviour of captive common marmosets, callithrix jacchus jacchus. | conditions of captivity of primates used in biomedical research may have deleterious effects on the welfare of the animals and consequently on the reliability of the research. we investigated the effects of cage size and cage complexity, two fundamental characteristics of captive conditions, on the behaviour of the common marmoset (callithrix jacchus jacchus). we found an increase in the general level of activity and significant variation in the frequencies of specific behaviours with an increas ... | 1996 | 8938618 |
the biobehavioral consequences of psychogenic stress in a small, social primate (callithrix jacchus jacchus). | the biobehavioral consequences of psychogenic stress were examined using neuroendocrine and ethological methods in a captive colony of common marmosets (callithrix jacchus jacchus). specifically, hypothalamic-pituitary-adrenal (hpa) axis reactivity was evaluated as a function of gender and social status in four consecutive social environments [(1) stable heterosexual pairs; (2) isolation; (3) unstable peer groups; and (4) stable peer groups], by measuring both basal plasma cortisol, adrenocortic ... | 1996 | 8874833 |
expression of integrins in marmoset (callithrix jacchus) ovary during folliculogenesis. | integrins were localized immunohistochemically in marmoset ovaries (callithrix jacchus) of defined cycle stages. with monoclonal antibodies against beta 1, alpha 2, alpha 3, and alpha 6 integrin subunits, immunoreactivity was predominantly found in ovaries of the follicular phase. in the luteal phase, non-luteal cells, e.g. fibroblasts or endothelial cells expressed beta 1, alpha 2, or alpha 6 integrins. immunostaining for the beta 1 subunit was strongest in granulosa cells of all growing follic ... | 1996 | 8760853 |
intraventricular infusion of basic fibroblast growth factor (bfgf) in the mptp-treated common marmoset. | basic fibroblast growth factor (bfgf) prevents damage to the nigrostriatal system in rodents. we now report the effects of bfgf administered by intraventricular infusion to adult common marmosets (callithrix jacchus) previously rendered parkinsonian by the administration of 1-methy-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). infusion commenced 10 weeks after mptp treatment and the animals received bfgf in low (1.8 micrograms/l), medium (18 micrograms/l), or high (180 micrograms/l) doses over a 2 ... | 1996 | 8807747 |
the digestive strategy of the common marmoset, callithrix jacchus. | digestive tract morphology and function were studied in the common marmoset (callithrix jacchus), a small (350 g) exudivore with a well-developed caecum. transit times (times of first appearance of the markers in the faeces following a pulse dose in the food) were similar for co-edta, which marks the fluid phase of the digesta, and cr-mordanted cell walls, which marked the large (600-1200 microns) particulate phase of the digesta. however, mean retention time (the average time taken for the mark ... | 1996 | 8925425 |
monitoring and controlling reproduction in captive common marmosets on the basis of urinary oestrogen metabolites. | non-invasive methods for routine monitoring of reproductive states and reproduction control in large colonies of captive callithrix jacchus have been developed. immunoactive urinary oestrone-3-conjugates (e1c) were measured during non-conception cycles (n = 5) and pregnancy (n = 7). using plasma progesterone levels to time ovulation, ovulation was quantitatively estimated by a) calculating the first e1c rise and b) by establishing an e1c threshold. ovulation was thus defined as taking place 4 da ... | 1996 | 8783179 |
c-cells of marmosets (callithrix jacchus). | the localization and fine structure of c-cells of the thyroid glands from 31 marmosets (callithrix jacchus) of different age groups (newborn to 11 years old) were investigated by electron microscopy and immunomorphology (apaap, calcitonin). calcitonin-positive cells were found concentrated in the middle third of the gland. their localization in the follicular wall or in the interstitial space could not clearly be demonstrated by light microscopy. in adult animals, they were always located within ... | 1996 | 8638770 |
spontaneous lesions detected in the common cotton-eared marmosets (callithrix jacchus). | spontaneous lesions in the common cotton-eared marmosets (callithrix jacchus), which were maintained in our laboratory or were purchased from a commercial breeder, were examined histopathologically. there were 39 males and 22 females, between the ages of 7 and 100 months. the most interesting finding noted was extramedullary hematopoiesis, which was observed in the mesenteric lymph nodes, spleen, liver, kidney, adrenal gland, and cerebral choroid plexus. megakaryocytes were frequently observed i ... | 1996 | 8777223 |
influence of semen collection method on ejaculate characteristics in the common marmoset, callithrix jacchus. | a source of normal spermatozoa (sperm) is required for many andrological and reproductive studies. ideally the method used for semen collection should be repeatable and reliable but should not influence sperm characteristics or sperm function. two methods of semen collection from marmosets, vaginal washing after copulation and electroejaculation, were compared in terms of the success rate in obtaining samples and the characteristics of the sperm suspensions. vaginal washing was shown to be a rel ... | 2006 | 8723441 |
an appraisal of the antiparkinsonian activity of piribedil in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated common marmosets. | the d2 dopamine agonist piribedil is not widely used in the treatment of parkinson's disease because it was thought to be effective mainly on parkinsonian tremor and to produce a high incidence of peripheral side effects, particular nausea. in this study, we used 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-treated primates to reevaluate the antiparkinsonian ability of piribedil after its oral administration in the presence or absence of domperidone pretreatment. adult common marmosets (c ... | 1996 | 8684381 |
dopamine d3 receptors in the basal ganglia of the common marmoset and following mptp and l-dopa treatment. | the distribution of the dopamine d3 receptor was studied by receptor autoradiography using [3h]7-oh-dpat in striatal and extrastriatal brain regions of the common marmoset (callithrix jacchus). saturation studies demonstrated that [3h]7-oh-dpat bound with similar affinity to different regions of marmoset brain. in normal marmosets, specific [3h]7-oh-dpat binding was found in both striatal and extrastriatal regions. very high levels of specific [3h]7-oh-dpat binding were detected in the islands o ... | 1996 | 8833762 |
occurrence of an infanticide within a captive polygynous group of common marmosets, callithrix jacchus. | | 1996 | 8990517 |
metabolism of reproductive steroids during the ovarian cycle in two species of callitrichids, saguinus oedipus and callithrix jacchus, and estimation of the ovulatory period from fecal steroids. | gonadal steroids were measured in daily fecal samples providing comparative data on steroid metabolism in two genera of new world primates. circulating bioactive lh and progesterone concentrations and fecal progesterone, pregnanediol, estradiol, and estrone concentrations were measured by collecting blood and daily fecal samples from four captive common marmoset females and four cotton-top tamarin females for 30 days. high recoveries (> 80%) of labeled steroids that were added directly to the fe ... | 1996 | 8838005 |
genetic and environmental impacts on litter size and early infant survival in three species of callitrichids. | callitrichids are unusual among anthropoid primates in that they can deliver one to four offspring per litter in captivity. factors underlying intraspecific variation in litter size are unclear. data from the oak ridge associated universities (orau) marmoset research center provided an opportunity to investigate determinants of variation in (1) average litter size at birth and (2) average litter size surviving to 2 weeks of age in saguinus fuscicollis, s. oedipus, and callithrix jacchus. the obj ... | 2003 | 8742821 |
patterns of prenatal survival in the common marmoset (callithrix jacchus). | fifty common marmoset pregnancies were monitored using ultrasound. the objective was to ascertain if fetal mortality was related to litter size. prior to analysis we determined abortion rate and litter size were not influenced by repeated ultrasound. mortality was unrelated to litter size and occurred fairly late in gestation. all singletons born in this study began gestation as twins. it is hypothesized that marmosets may be able to adjust litter size late in pregnancy in response to proximate ... | 1996 | 8740954 |
thalidomide derivatives and the immune system. 6. effects of two derivatives with no obvious teratogenic potency on the pattern of integrins and other surface receptors on blood cells of marmosets. | the two thalidomide (thd) derivatives beta-em12 and phthalimidophthalimide (phtpht), which exhibit no obvious teratogenicity, were tested for their ability to induce changes in the pattern of lymphocyte subpopulations, and especially changes in integrin receptors, in marmosets (callithrix jacchus). previously, thd and its highly teratogenic derivative alpha-em12 had been found to alter the expression of adhesion molecules, such as cd2 (lfa-2) or cd11a/cd18 (lfa-1). none of these typical effects ... | 1996 | 8538370 |
representation of a species-specific vocalization in the primary auditory cortex of the common marmoset: temporal and spectral characteristics. | 1. the temporal and spectral characteristics of neural representations of a behaviorally important species-specific vocalization were studied in neuronal populations of the primary auditory cortex (a1) of barbiturate-anesthetized adult common marmosets (callithrix jacchus), using both natural and synthetic vocalizations. the natural vocalizations used in electrophysiological experiments were recorded from the animals under study or from their conspecifics. these calls were frequently produced in ... | 1995 | 8747224 |
visual responses in the lateral geniculate nucleus of dichromatic and trichromatic marmosets (callithrix jacchus). | new-world primates such as the marmoset (callithrix jacchus) show polymorphism for the middle- to long-wavelength sensitive cone pigments. each x-chromosome carries a gene for only one of three possible pigments. all males are thus dichromats, but some females will be trichromats. we have investigated the responses of cells of the parvocellular (pc) and magnocellular (mc) systems within animals from a single marmoset family. the middle- to long-wavelength pigment of dichromats was identified phy ... | 1995 | 8613728 |
chronic l-dopa administration induces dyskinesias in the 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine-treated common marmoset (callithrix jacchus). | dyskinesias occur in the majority of patients with parkinson's disease chronically treated with l-dopa and also occur in several nonhuman primate species after 1-methyl-4phenyl-1,2,3,6-tetrahydropyridine (mptp) and l-dopa treatment. the common marmoset (callithrix jacchus) shows parkinsonian motor deficits after mptp administration, and we now report dyskinesias occurring in this species during chronic l-dopa exposure. marmosets rendered chronically parkinsonian after mptp administration were tr ... | 1995 | 8749992 |
the thyroid gland of callithrix jacchus in organ culture. | thyroid glands from 7 marmosets (callithrix jacchus) of different age groups (newborn, 2 weeks, 2, 7, 8 and 11 months, and 8 years) were grown as organ culture according to trowell at the medium/air interphase for 3 to 30 days. the morphology of thyroid tissue was well preserved until the end of the culture period. necroses were only occasionally seen in connective tissue. in contrast to the in vivo situation, the number of lysosome-like inclusions changed considerably and cell-cell contacts bec ... | 1995 | 8574010 |
baseline and mitomycin c (mmc)-induced sister-chromatid exchanges in xx and xy cells of callithrix jacchus chimeric twins. | lymphocytes from chimeric individuals of the species callithrix jacchus (primates) were examined to evaluate differences in the frequency of sister chromatid exchanges (sce) between xx and xy cells. the aim was to discover whether sce differ according to genetic sex and whether xx and xy cells show a different sensitivity to sce inducing agents. this experimental model has enabled us to eliminate the possible differences caused by environmental factors. the results obtained do not reveal signifi ... | 1995 | 7565907 |
effects of low doses of cholinesterase inhibitors on behavioral performance of robot-tested marmosets. | to investigate at which dose levels undesirable effects started, behavioural performance and several physiological parameters were measured in marmosets (callithrix jacchus) after soman (1.75 and 3.5 micrograms/kg), sarin (3 and 6 micrograms/kg), physostigmine (10 and 20 micrograms/kg), and pyridostigmine (200 and 400 micrograms/kg). effects on performance were investigated with a discrete-trial, two-choice visual discrimination task and a hand-eye coordination task. the former test appeared mor ... | 2013 | 7667367 |
the interstitial space of the thyroid gland of marmosets (callithrix jacchus). | the interstitial space of the thyroid gland of adult marmosets contains, like the stroma of other organs, cells and intercellular substance (matrix), blood vessels (predominantly capillaries), lymph vessels and unmyelinated nerves. it is demarcated from the follicular epithelium, the capillaries and schwann cells by a basal lamina (bl). the perifollicular bl shows thickenings of up to 3 microns over long distances or a multilayered arrangement. these thickened segments exhibit numerous epithelia ... | 1995 | 7625607 |
behavior and progesterone levels in callithrix jacchus females. | in callitrichids, and especially in the callithrix and saguinus genera, reproductive suppression maintains the breeding exclusivity of dominant females. it has been suggested that dominance may be inferred from agonistic behavior of females. the purpose of this study was to assess the adequacy of behaviors as indicators of hormonal status in callithrix jacchus females. two pairs of twin females were observed for affiliative, agonistic and sexual behaviors for 20 weeks, in four stages of increasi ... | 1995 | 8555980 |
short- and long-term changes in striatal and extrastriatal dopamine uptake sites in the mptp-treated common marmoset. | the 'short-term' (15-30 days) and 'long-term' (18-42 months) effects of the systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) on [3h]mazindol binding to dopamine uptake sites was investigated in the common marmoset. in the 'short-term' mptp-treated group, [3h]mazindol binding was reduced in the caudate-putamen (by -82 to -98% with respect to controls), substantia nigra pars compacta (-71 to -84%), ventral tegmental area (-72%) and nucleus accumbens (-54%). [3h]mazind ... | 1995 | 7493614 |
short and long-term changes in cerebral [14c]-2-deoxyglucose uptake in the mptp-treated marmoset: relationship to locomotor activity. | the "short-term" (0.7 +/- 0.1 months post-mptp) and "long-term" effects (36.7 +/- 4.4 months) of mptp treatment on motor behaviour and [14c]-2dg uptake were investigated in the common marmoset. the subcutaneous administration of mptp greatly reduced locomotor activity (-94% with respect to controls) and induced motor disability in the "short-term" mptp-treated marmoset group. in the "long-term" mptp group, mptp treatment did not significantly affect locomotor activity (-27% with respect to contr ... | 1995 | 8695058 |
hand, mouth and eye preferences in the common marmoset (callithrix jacchus). | motor and sensory preferences were measured for 8 common marmosets (callithrix jacchus). three types of motor function were examined: spontaneous feeding, mouth use when chewing and visuospatial reaching. eye preference was used as an index of sensory lateralization. the marmosets displayed individual preferences for the performance of the motor tasks, but no group biases were revealed. correlations between preferences displayed on the motor tests suggest that one hemisphere may control spontane ... | 1995 | 8613126 |
health problems of callithrix jacchus in captivity. | a 20-year retrospective study was carried out to determine the prevalence of diseases occurring in 265 (155 males and 110 females) common marmosets (callithrix jacchus), kept at the são paulo zoo. a total of 564 clinical disorders were detected: digestive problems, 50.2% (protozoa, 44.3%; helminths, 26.3%; bacteria, 7.0%; non-especific causes, 22.4%); respiratory problems (pneumonia), 16.3%; injuries, 13.8%; nutritional deficiency, 4.4%; reproductive problems (obstetrical) 2.5%; septicemia, 1.6% ... | 1995 | 7581030 |
the effect of parturition on the interactions within pairs of common marmosets (callithrix jacchus). | the relationship within common marmoset (callithrix jacchus) pairs is based on pair-bond formation. this pair-bond is important for the successful rearing of the young and for the enhancement of reproductive success. female marmosets bear twins which are carried mainly by males starting on the first day after the birth of the infants. little is known, however, about the patterns of sociosexual interaction between callitrichid pairs and how these interactions change after the arrival of offspring ... | 1995 | 7581018 |
social implications of gummivory in marmosets. | gummivory or exudate feeding is a major dietary specialization which has received relatively little attention in the literature. while plant exudates contribute to the diet of many primate species, we suggest that the callitrichid species cebuella pygmaea and callithrix jacchus are obligate exudate feeders under free-ranging conditions. callithrix jacchus provides an excellent model for examining the effects of exudate feeding and foraging upon social behavior, since other callitrichid species o ... | 1994 | 7864061 |
molecular mass and isoelectric properties of pituitary and urinary gonadotrophins in callitrichid primates. | in this study, the molecular masses and isoelectric characteristics of pituitary lh and fsh in two species of callitrichid primate, the common marmoset (callithrix jacchus) and the cotton-top tamarin (saguinus oedipus), were determined. comparative data for urine samples from callithrix jacchus are also presented. the separation of gonadotrophins from pituitary extracts and urine was performed under nonreducing conditions using sds-page and isoelectric focusing procedures. hormone activity in ge ... | 1994 | 7861403 |
growth factors (egf, igf-i) modulate the morphological differentiation of adult marmoset (callithrix jacchus) sertoli cells in vitro. | the effects of epidermal growth factor (egf) and insulin-like growth factor i (igf-i) on mature marmoset (callithrix jacchus) sertoli cells in vitro were investigated using light and electron microscopic and histochemical means. the morphological data were substantiated by morphometric analysis at the electron microscopic level. in a bicameral chamber system, cultured sertoli cells displayed a high degree of ultrastructural differentiation and exhibited a polarized appearance. basally located ti ... | 2006 | 7860420 |
effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) in the common marmoset. | the effects of bifemelane on parkinsonism were shown in mptp-treated common marmosets. the administration of bifemelane increased locomotor activity in mptp-treated marmosets but not in normal control marmosets. in a microdialysis study, extracellular levels of dopamine and its metabolites increased following the administration of bifemelane. these results indicate that it is worth studying the effects of bifemelane hydrochloride on patients with parkinson's disease. | 1994 | 7816348 |
3h11, a unique cell surface molecule involved in the function of the cd45ra+ subset of cd4+ cells. | we have developed a mab anti-3h11 by immunizing mice with a t cell line derived from the callithrix jacchus (common marmoset). anti-3h11 is reactive with approximately 48% of unfractionated t cells, 62% of cd4+ cells and 39% of cd8+ cells. among cd4 cells, anti-3h11 preferentially reacts with the cd45ra+ t cell subset. the majority of helper activity for pokeweed mitogen (pwm)-driven b cell igg synthesis and t cell response to recall antigen such as tetanus toxoid was found within the 3h11-cd4 c ... | 1994 | 7981142 |
nonsurgical uterine stage preimplantation embryo collection from the common marmoset. | a nonsurgical technique for the recovery of uterine stage preimplantation embryos was developed for the common marmoset (callithrix jacchus). in 54 flush attempts, using 19 different animals, 54 morphologically normal embryos, seven unfertilized oocytes or degenerate embryos, and five empty zonae pellucidae were recovered, giving a recovery rate of 1.0 embryo per flush or 1.2 ovulation products per flush. because the ovarian cycles of common marmosets can be synchronized with prostaglandin pgf2 ... | 1994 | 7897640 |
spontaneous adrenal and hepatic myelolipomas in the common marmoset. | myelolipomas occurring simultaneously in the adrenal and liver were found in a 2.7-yr-old, bred female common marmoset (callithrix jacchus). the animal bore single adrenal and multiple hepatic myelolipomas. the adrenal myelolipoma consisted of mature adipose cells and focal collections of normal hematopoietic elements and was unencapsulated. in the liver, the myelolipomas, which were partially encapsulated, included a large amount of hematopoietic tissue and adipose cells that resembled normal b ... | 2017 | 7817133 |
mitochondrial abnormalities in nigral neurons of the marmoset and macaca fascicularis treated with mptp. | in a previous study we observed the processes determining the cellular death in nigral neurons of macaca fascicularis and common marmoset treated with mptp. the purpose of this study is to consider, in substantia nigra neurons of the same animals, mitochondrial abnormalities caused by neurotoxin. three macaca fascicularis and 5 common marmosets, respectively treated with 3 and 4 mg/kg of mptp dissolved in saline + 10% ethanol, were suppressed by means of an i.v. injection phenobarbital. the subs ... | 1994 | 7831058 |
toxicity of a novel hmg-coa reductase inhibitor in the common marmoset (callithrix jacchus). | 1. gr95030x, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a (hmg-coa) reductase, was administered daily to marmosets by gavage. in a maximum repeatable dose (mrd) study, doses of up to 30 mg kg-1 day-1 were administered for 49 days. in a chronic study, animals received dosages equivalent to 0, 1, 2.5, 7.5 and 20 mg kg-1 day-1 for 204 or 205 days. some animals were maintained without treatment for a recovery period of 29 or 30 days. 2. clinical signs included poor coat condition, wea ... | 1994 | 8043318 |
a simple automated test to measure exploratory and motor activity of marmosets. | an automated device is described to test the exploratory and motor activity of common marmosets (callithrix jacchus). the device consists of four boxes interconnected by pvc tubes. the presence of an animal in a box is detected by a photocell. calibration takes place with an electric model train. movements of the animal from one box to another are detected by disappearance from one and appearance in another box. the apparatus is linked to a pc. the effects of two doses of methamphetamine and of ... | 1994 | 8029258 |
the common marmoset as a model for nutritional impacts upon reproduction. | | 1994 | 8154709 |
the regulation of maternal behaviour in marmosets and tamarins. | this article reviews a long-term investigation into the roles of (1) experience obtained with infants during development and postnatally, and (2) levels of reproductive-steroid hormones during late pregnancy, in the regulation of maternal caregiving motivation and behaviour in the red-bellied tamarin (saguinus labiatus) and the common marmoset (callithrix jacchus) (family callitrichidae, order primates). both observational studies, e.g. post hoc analysis of the relationship between developmental ... | 1993 | 24896945 |
the neuropathology of trimethyltin in the marmoset (callithrix jacchus) hippocampal formation. | the effects of single and repeated doses of trimethyltin (tmt) treatment on the central nervous system (cns) of the marmoset were investigated. for the acute-dose experiment adult animals were administered 3 mg/kg of tmt chloride (ip) and were then observed for changes in behavior. within 24 hr postinjection all animals developed tremors, ataxia, and unresponsiveness. half of the animals had severe clinical deterioration and died at 2 to 3 days following treatment. surviving marmosets were sacri ... | 1993 | 7507820 |
illustrated guide to surgical technique for vasectomy of the common marmoset. | the surgical technique for vasectomy of the common marmoset (callithrix jacchus) is described and illustrated. | 1993 | 8277713 |
evidence for the experimental transmission of cerebral beta-amyloidosis to primates. | the brains of three marmosets (callithrix jacchus) injected intracerebrally 6-7 years earlier with brain tissue from a patient with early onset alzheimer's disease were found to contain moderate numbers of amyloid plaques with associated argyrophilic dystrophic neurites and cerebral amyloid angiopathy but no neurofibrillary tangles. the plaques and vascular amyloid stained positively with antibodies to beta (a4)-protein. the brains of three age-matched control marmosets from the same colony did ... | 1993 | 8217779 |
behavioral effects of cholinergic grafts. | experimental work in animals and, to a more limited extent, in humans, has demonstrated that the cholinergic system is involved in mechanisms which control learning and memory. since there is cholinergic loss in a variety of dementing illnesses, any treatment designed to alleviate the mental symptoms of these diseases must address the issue of cholinergic dysfunction even if other treatments are also required to overcome other neurotransmitter imbalances. work in rodents has demonstrated that ch ... | 1993 | 8239295 |
experimental induction of beta-amyloid plaques and cerebral angiopathy in primates. | moderate numbers of amyloid plaques with associated argyrophilic dystrophic neurites and cerebral amyloid angiopathy (caa) but no neurofibrillary tangles (nfts) were found in the brains of 3 middle-aged common marmosets (callithrix jacchus) inoculated intracerebrally (i.c.) 6-7 years earlier with brain tissue from a patient with early onset alzheimer's disease. the plaques and vascular amyloid stained positively with antibodies to beta (a4)-protein. the brains of 3 age-matched control marmosets ... | 1993 | 8239287 |
measurement of faecal steroids for monitoring ovarian function in new world primates, callitrichidae. | measurement of immunoreactive progesterone, pregnanediol and oestradiol in faeces collected throughout ovarian cycles in three species of callitrichid primates is reported. faecal hormone concentrations were compared with plasma progesterone profiles during pgf2 alpha-controlled (n = 7) and natural (n = 8) cycles in callithrix jacchus and saguinus fuscicollis, respectively, and with urinary oestrone conjugates during five cycles in saguinus oedipus. unconjugated steroids, which predominated over ... | 1993 | 8283445 |
audition and the auditory pathway of a vocal new world primate, the common marmoset. | | 1993 | 8210411 |
sexual and aggressive behaviour of adult male marmosets (callithrix jacchus) castrated neonatally, prepubertally, or in adulthood. | during early postnatal development, males of some primate species exhibit higher levels of plasma testosterone than females. the possible significance of this for behavioural development was examined in male marmosets castrated neonatally (nc), prepubertally (pc), or in adulthood (ac) and reared in their natal groups. age-matched intact (ai) adult males served as controls. all males were removed from their natal groups as adults for pair testing with unfamiliar conspecific males and females. nc ... | 1993 | 8372125 |
pre- and postnatal development of the primary visual cortex of the common marmoset. i. a changing space for synaptogenesis. | the primary visual cortex of callithrix jacchus occupies a large portion of the occipital neocortex and can be safely delineated from fetal stages onwards. in 20 animals ranging in age from fetal to adult age the morphological development of area 17 was evaluated and compared with the growth of whole brain, skull, and head size. cortical thickness, surface area, and volume of the area were determined in addition to predominant growth directions. the volume of area 17 approximately doubles betwee ... | 1993 | 8340495 |
ocular development and visual deprivation myopia in the common marmoset (callithrix jacchus). | the normal postnatal ocular development of the common marmoset (callithrix jacchus) and the effects of visual deprivation on eye growth and refractive state are described. the marmoset normally undergoes a developmental process of emmetropization from high hyperopia at birth. this emmetropization is easily disrupted by visual deprivation produced by lid-suture. myopia and axial elongation of the vitreous chamber are induced by visual deprivations of 12, 5, and 3 weeks duration. the development o ... | 1993 | 8333155 |
arthritis of the spondyloarthropathy variety in callithrix jacchus. | sixty skeletons of callithrix jacchus were examined to identify spondyloarthropathy. erosive disease in callithrix was confirmed as spondyloarthropathy on the basis of diagnostic sacroiliac erosions, syndesmophyte formation, and the nature and distribution of the peripheral joint erosions. | 1993 | 8289220 |
alterations in striatal and extrastriatal d-1 and d-2 dopamine receptors in the mptp-treated common marmoset: an autoradiographic study. | in adult common marmosets (callithrix jacchus), mptp (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) treatment induced almost total depletion of cells in the substantia nigra pars compacts (snc) but partial cell loss in the ventral tegmental area (vta). there was severe depletion of [3h]-mazindol binding to dopamine (da) uptake sites in the caudate, putamen, and snc. the loss of [3h]-mazindol binding in the nucleus accumbens (nac) and olfactory tubercle (ot) was less marked. [3h]-mazindol binding ... | 1993 | 8332947 |
alteration of circadian period length does not influence the ovarian cycle length in common marmosets, callithrix j. jacchus (primates). | to investigate the coupling between the circadian system and the regulation of the ovarian cycle in nonhuman primates, the effect of zeitgeber-induced alterations of the circadian period (23 vs 26 h) on the ovarian cycle length was studied in the long-cycling polyestrous common marmoset, callithrix j. jacchus. for that purpose, six female marmosets were isolated for approximately 4 months each under artificial lighting regimens of 23 h [light-dark (ld) 11.5:11.5] and of 26 h (ld 13:13; 300:0.03 ... | 1993 | 8319317 |
urinary estradiol-17 beta excretion in common marmosets, callithrix jacchus: diurnal pattern and relationship between creatinine-related values and excreted amount. | 1. the diurnal pattern of urinary estradiol and creatinine excretion was investigated in order to evaluate the relationship between total estradiol excretion per day and the estradiol concentration or the estradiol-to-creatinine ratio from single urine samples in female common marmosets (callithrix j. jacchus). 2. during a 36-day period, urine was collected from five adult female marmosets in 3-hr intervals during the light time of an ld 12:12 (400:0.1 lx) which corresponded to the animals' acti ... | 1993 | 8101157 |
a selective maob inhibitor ro19-6327 potentiates the effects of levodopa on parkinsonism induced by mptp in the common marmoset. | the effects of the selective and reversible maob inhibitor ro19-6327 on parkinsonism in common marmosets, induced by mptp were studied. combined administration of ro19-6327 with benserazide/levodopa potentiated the effects of levodopa to reverse akinesia. in a microdialysis study, the administration of ro19-6327 was found to minimize the increase in metabolites of dopamine (da) following injection of levodopa. these results suggest that ro19-6327 suppresses the metabolism of da, resulting in inc ... | 1993 | 8321428 |
effects of sex steroids on maternal motivation in the common marmoset (callithrix jacchus): development and application of an operant system with maternal reinforcement. | we developed an operant paradigm for measuring effects of reproductive steroids on maternal motivation in common marmosets (callithrix jacchus). conditioned response regulated females' exposure to maternal reinforcement. nulliparous females (n = 15) with experience with infants in social groups were subjects. the paradigm was validated by examining (a) effects of reinforcing stimuli on affective behavior in a nonoperant paradigm, (b) responsiveness of operant performance to changes in reinforcin ... | 1993 | 8444024 |
a t.e.m. stereological analysis of blood vessels and nerves in marmoset periodontal ligament following endodontics and magnetic incisor extrusion. | maxillary incisor fracture is a common dental injury. it is frequently treated by endodontic therapy, orthodontic extrusion, and a retention period. the aim of the study was to mimic this regime and stereologically quantify the vascular and neural reconstitution of the periodontal ligament (pdl). ten marmosets (callithrix jacchus) had the right maxillary incisor crown removed, root canal treatment, and magnetic incisor root extrusion of 1.2 mm. after incisor retention for 9 weeks, the animals we ... | 1993 | 8436195 |
thalidomide derivatives and the immune system. i. changes in the pattern of integrin receptors and other surface markers on t lymphocyte subpopulations of marmoset blood. | treatment of marmosets (callithrix jacchus) with thalidomide (thd) or its derivative em12 (which is also teratogenic, but more stable to hydrolysis) resulted in the lack of reaction of adhesion surface receptors (integrins) on t lymphocytes in venous blood. lymphocyte subsets appeared, for example cd4+cd2-, which are not found under normal conditions. (a) there was no clear effect of the treatments on the total number of leukocytes or lymphocytes or on the total number of cd4+ or cd8+ t lymphocy ... | 1993 | 8452474 |
effects of ibotenic acid-induced neuronal degeneration in the hypothalamus upon proceptivity and sexual receptivity in the female marmoset (callithrix jacchus). | the sexual behaviour of 16, oestradiol-treated, ovariectomized common marmosets was recorded before and after bilateral microinfusions of ibotenic acid (n = 8) or isotonic saline (n = 8) into the hypothalamus. ibotenic acid-induced neuronal degeneration occurred in 5 females, mainly affecting the anterior and dorsomedial hypothalamus. marked decreases in proceptivity (tongue-flicking, staring and immobile displays) occurred after ibotenic acid lesions, whereas sexual receptivity (refusals and te ... | 1992 | 21554659 |
tyrosine hydroxylase-immunoreactive neurons in the nucleus basalis of the common marmoset (callithrix jacchus). | in the course of characterizing the distribution of putative catecholaminergic neurons in the brain of the common marmoset, we encountered a population of such cells in the basal forebrain. tyrosine hydroxylase-immunoreactive neurons are abundant within the nucleus basalis magnocellularis throughout its entire rostrocaudal extent, but not in other cholinergic basal forebrain nuclei. most tyrosine hydroxylase-immunoreactive cells are large and multipolar. double staining with antibodies to cholin ... | 1992 | 1280282 |
zonal differentiation of the marmoset (callithrix jacchus) endometrium. | the differentiation of the marmoset (callithrix jacchus) endometrium under different steroid hormone levels was investigated by electron microscopy and by the binding of different antibodies directed against collagen types. based on differences in the glandular and interglandular compartments, the endometrium of sexually mature common marmosets consists of 3 zones: basal, adluminal and luminal. hormone-dependent appearances are characterised. with low steroid concentrations, intercellular spaces ... | 1992 | 1295868 |
developmental biology of the common marmoset: proposal for a "postnatal staging". | the published knowledge on neurobiological, psychological, and ethological aspects of development in callithrix jacchus is still limited. we have collected published and unpublished data from several callithrix colonies and pooled information on criteria for developmental progress and maturation using a questionnaire sent to numerous experts in the field. the data suggest that developmental stages can be defined not only for the embryonic and fetal but also for the postnatal period. based on mul ... | 1992 | 1297850 |
age determination of common marmosets (callithrix jacchus) by radiographic examination of skeletal development. | seventy-four animals were examined radiographically to determine the skeletal development of the common marmoset (callithrix jacchus) from 6 months of age. twenty-one epiphyses were examined and five stages of ossification were described for each. the animals were divided into nine groups, according to age, and a table of the stage of ossification and age was produced, which may be used for determining the age of animals of unknown history. | 1992 | 1404334 |
intercellular communication between cultured granulosa cells of the marmoset (callithrix jacchus). | the influence of follicle-stimulating hormone, forskolin, insulin-like growth factor type i, epidermal growth factor, and 12-tetradecanoyl-phorbol-13-acetate on marmoset granulosa cell communication via gap junctions was investigated by morphological means and microinjection of carboxyfluorescein. gap junctions between neighbouring granulosa cells were present in all groups. the number, but not length, of gap junctions between marmoset granulosa cells increased when the cells had been treated wi ... | 1992 | 1617703 |
sister-chromatid exchange rates in xx and xy cells of ten chimeric callithrix jacchus individuals. | in order to ascertain whether or not sister-chromatid exchange (sce) differs in relation to sex, sce rates in xx and xy cells from 10 specimens of marmoset (callithrix jacchus) were examined. the choice of this primate is particularly suitable for three reasons: most individuals have a chimeric constitution, the x chromosome is quite large and the y chromosome is particularly small. therefore, the influence of possible differences in their exposure to the external environment can be eliminated. ... | 1992 | 1374152 |
the distribution of 5-ht3 recognition sites in the marmoset brain. | the distribution of the binding of [3h]gr65630 (0.2 nm) to putative 5-ht3 recognition sites in the brain of the common marmoset was assessed using autoradiography. specific binding was heterogeneously distributed with the highest densities found in discrete nuclei of the lower medulla (nucleus tractus solitarii, dorsal motor nucleus of the vagus nerve, nucleus of spinal trigeminal nerve tract and the area postrema). in forebrain areas, relatively high binding densities were located in the medial ... | 1992 | 1516650 |
sex ratio and mortality in a laboratory colony of the common marmoset (callithrix jacchus). | in a retrospective study sex ratio and mortality were analysed in a captive colony of common marmosets (callithrix jacchus). seven hundred and thirty-five infants in 294 litters (20 singletons, 119 twins, 140 triplets, 14 quadruplets) out of 57 breeding females were evaluated. the sex ratio at birth was 0.95 males:1.0 females. the frequency of males and females, as well as the sex composition of twins and triplets confirm the assumption of dizygotic twinning in the common marmoset. according to ... | 1992 | 1518282 |
place preference behaviour in the common marmoset (callithrix jacchus): carey gj, domeney am, costall b, naylor rj, postgraduate studies in pharmacology, the school of pharmacy, university of bradford, bradford, west yorkshire, bd7 1dp. | | 1992 | 22291332 |
fine structure of the vomeronasal organ in the common marmoset (callithrix jacchus). | | 1992 | 1306179 |
collection and analysis of semen from the common marmoset (callithrix jacchus). | the authors examined the seminal characteristics of 16 male common marmosets (callithrix jacchus) to provide baseline data for future studies of the reproductive biology of this species. semen samples were collected by electroejaculation. there was considerable inter- and intra-male variation in all seminal characteristics. the median seminal volume was 30 microliters (range 8 to 85 microliters), and the median total sperm count was 5.1 x 10(6) sperm (range, 0.1 to 43 x 10(6]. the median progres ... | 2003 | 1917685 |
development of a monoclonal antibody, anti-6c2, which is involved in the interaction of cd4 t helper cells and activated b cells. | we have developed a mab anti-6c2, by immunizing mice with t cell line derived from the callithrix jacchus (common marmoset). anti-6c2 is reactive with approximately 50% of unfractionated t cells, 50% of cd4+ cells, and 40% of cd8+ cells. regarding cd4+ cells, anti-6c2-reactive cells substantially overlap with the cd29+cd45ro+ th cell population. moreover, anti-6c2 can divide these t cells into 6c2+ and 6c2- subpopulations. the cd4+cd45ro+6c2+ cells maximally respond to soluble ag such as tetanus ... | 1991 | 1706389 |
penile spines affect copulatory behaviour in a primate (callithrix jacchus). | androgen-dependent, keratinized "spines" occur on the glans penis in many rodents, primates and other mammals. since penile spines overlie dermal tactile receptors, they may play a role in copulatory behaviour. an experiment was conducted to test this hypothesis. sixteen sexually experienced adult male marmosets were paired with ovariectomized females before, and after, removal of penile spines (using thioglycollate cream applied to the glans under anaesthesia) or a sham operation. spine removal ... | 1991 | 2062934 |
ultrastructural and histochemical characterization of marmoset (callithrix jacchus) leydig cells during postnatal development. | leydig cell development was investigated in the marmoset (callithrix jacchus) testis from 24 h post partum (pp) up to sexual maturity, using ultrastructural and histochemical methods. electron microscopically three different leydig cell (lc) types could be distinguished: neonatal, immature and adult lcs. neonatal lcs exhibited a round nucleus, large tubular mitochondria, abundant smooth endoplasmic reticulum (ser), and few small fat vesicles. the typical immature lcs showed a lobulated nucleus, ... | 1991 | 1903613 |
urinary protein pattern reflects social rank in male common marmosets (callithrix jacchus). | | 1991 | 1794772 |
the local domain for divergence of subcortical afferents to the striate and extrastriate visual cortex in the common marmoset (callithrix jacchus): a multiple labelling study. | in the common marmoset (callithrix jacchus), the cortical projection from the pulvinar and other diencephalic structures into the striate and prestriate cortex was investigated with various fluorescent retrograde tracers. single cortical injections as well as multiple injections at distances of 1-2 mm with one tracer into an extended but coherent cortical region were applied. fields with multiple injections were placed so that they touched each other (minimal distances 2 to 3 mm). retrogradely l ... | 1991 | 1712315 |
motor activity following the administration of selective d-1 and d-2 dopaminergic drugs to normal common marmosets. | in normal common marmosets administration of the d-1/d-2 agonist apomorphine or the selective d-2 agonist quinpirole caused a dose-dependent increase in motor activity and induced stereotyped behaviour. both the selective d-2 antagonist raclopride and the selective d-1 antagonist sch 23390 inhibited normal locomotor activity and induced catalepsy. quinpirole- and apomorphine-induced motor activity were potently inhibited by pretreatment with raclopride. the effects of quinpirole, but not apomorp ... | 1991 | 1686813 |
the effect of dietary change on in vitro erythrocyte haemolysis, skin lesions and alopecia in common marmosets (callithrix jacchus). | 1. the effect of dietary change on common marmosets (callithrix jacchus) exhibiting high in vitro erythrocyte haemolysis, skin lesions and alopecia was investigated. 2. the experimental diet was low in lipid, high in vitamin e and was devoid of n-3 long chain polyunsaturated fatty acids. 3. there were significant increases in the concentrations of plasma alpha-tocopherol (vitamin e) (p less than 0.05), all-trans retinol (vitamin a) (p less than 0.001) and total lipid (p less than 0.025), and a r ... | 1991 | 1685382 |
cell proliferation in the subependymal layer of the postnatal marmoset, callithrix jacchus. | cells of the subependymal layer (sel) have been shown to be capable of continued postnatal cell division throughout life in rodents. to determine if the primate brain behaves similarly, proliferative activity in the sel of the marmoset has been investigated by tritiated thymidine autoradiography and bromodeoxyuridine immunocytochemistry. both methods revealed the presence of dna-synthesizing cells at all postnatal ages studied. the labelling index (li), low at birth, reached a peak of almost 4% ... | 1990 | 2073725 |
central oxytocin stimulates luteinizing hormone release in the marmoset, a primate which fails to show lactationally-lnduced infertility. | in several species, including humans, suckling is known to suppress pulsatile gonadotrophin secretion and substantially reduce fertility (1). during suckling high titres of oxytocin are present in both plasma (2, 3) and cerebrospinal fluid (csf) (4) and there is some evidence that oxytocin is inhibitory to gonadotrophin secretion by an action on t h e central nervous system, (5, 6). the common marmoset, however, has a different physiological response and fails to show lactational infertility; ov ... | 1990 | 19215367 |
the facial artery of the common marmoset (callithrix jacchus). | the facial artery and its ramifications in 7 adult common marmosets (callithrix jacchus) were studied by the plastic injection method. the findings obtained are discussed in comparison with those for other primates. in the submandibular region, the facial artery arose from the external carotid artery at the height of the atlas via the linguofacial trunk on 10 of the total of 14 sides examined and independently on the other 4 sides. this common trunk always gave rise to the superior thyroid arter ... | 1990 | 2216318 |
screening procedure for assessment of ototoxicity in the common marmoset. | detection of drug-induced ototoxicity in safety evaluation studies of novel chemical entities is rarely attempted. where such examinations are included, they usually rely on reflex testing. the brainstem auditory evoked response can be measured with the use of externally positioned electrodes, and it monitors electrophysiologic responses to sound from the cochlear nerve and associated structures of the 8th cranial nerve. these responses have been reproducibly measured in sedated marmosets and th ... | 1990 | 2214803 |
a lobster claw abnormality in the common marmoset (callithrix jacchus). | a congenital abnormality of the digits, similar to the 'lobster claw' deformity of humans, was observed in 8 common marmosets. the condition varied in severity and in effect on the animals; it appeared to be due to a single autosomal recessive trait. | 1990 | 2366513 |
adenocarcinoma of the small intestine in a common marmoset (callithrix jacchus). | | 1990 | 2157108 |
[the distribution of different collagen types and laminin in the gingiva of the common marmoset (callithrix jacchus)]. | the distribution of the collagen types i, iii, iv, v, vi and of the glycoprotein laminin have been examined in the healthy gingiva of the marmoset with the indirect immunofluorescence method. it has been shown that collagen type i formed thick fibrils in a wave-like pattern, while collagen type iii formed thinner fibrils, especially under the epithelial basal membrane. collagen type iv and laminin showed a strong fluorescence in the basal membrane (epithelium, vessels, nerves). collagen type v h ... | 1990 | 2237364 |
immunofluorescence-microscopic localization of collagen type iv and vi, laminin and nidogen in the livers of callithrix jacchus during pre- and postnatal development. | the distribution of collagen type iv and vi, laminin and nidogen was investigated by immunofluorescence microscopy in the livers of marmosets (callithrix jacchus) at various stages of development, i.e. on days 93, 111, 116 and 134 of gestation, 1 day postpartum and at the mature stage. large amounts of collagen type iv could in all cases be demonstrated in the sinus wall and in all basal laminae outside the lobule. after the application of antibodies against collagen type vi the sinus wall showe ... | 1990 | 2117839 |