| topographical and topological organization of the thalamocortical projection to the striate and prestriate cortex in the marmoset (callithrix jacchus). | in eleven hemispheres of nine marmoset monkeys (callithrix jacchus), we have investigated the thalamo-cortical organization of the projections from the pulvinar to the striate and prestriate cortex. in each experiment, single or multiple injections of various retrograde fluorescent tracers were injected into adjacent regions or areas. in two experiments, horseradish peroxidase (hrp) was injected into the lateral geniculate nucleus (lgn) and the lateral pulvinar, respectively. the results show th ... | 1991 | 1712314 |
| transmammary transmission of mesocercariae of alaria marcianae (trematoda) in experimentally infected primates. | a lactating primate, callithrix jacchus, was infected experimentally with 600 mesocercariae of alaria marcianae 10 days after parturition to determine if she would transmit the mesocercariae to her offspring. her twin infants were examined 4 wk postinoculation and 16 mesocercariae were found in their tissues. the female was mated again and gave birth to a litter of triplets. she was not given additional mesocercariae. one infant died within hours of birth without suckling and was found negative ... | 1990 | 2254822 |
| [yersinia pseudotuberculosis in new world monkeys]. | it is reported on four cases of pseudotuberculosis in 2 saimiri sciureus, 1 callithrix jacchus/penicillata hybrid and 1 s. oedipus. the animals came from two different groups, one being infected with y. pseudotuberculosis serotype i, the other with y. pseudotuberculosis serotype ii. all cases showed intestinal infection of thermophile campylobacter. remarkable were severe haemorrhagic components and the distinct rhs-proliferation, especially in the mesenteric lymphatic nodes. | 1991 | 2015031 |
| transfer of various polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdds and pcdfs) via placenta and through milk in a marmoset monkey. | a defined mixture of polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdds and pcdfs) was subcutaneously administered to a pregnant marmoset monkey (callithrix jacchus) 11 weeks prior to delivery. transfer of pcdds and pcdfs via placenta and mother's milk was investigated by measurement of concentrations in a newborn 1 day after birth and in an infant of the same litter after a lactation period of 33 days. furthermore, comparative measurements were performed in different tissues of the moth ... | 1990 | 2128593 |
| inhibin secretion during the ovulatory cycle and pregnancy in the common marmoset monkey. | changes in plasma concentrations of immunoreactive inhibin in the reproductively cyclic, pregnant and ovariectomized female marmoset monkey (callithrix jacchus) were measured with a heterologous radioimmunoassay. the pattern of inhibin secretion in five marmosets studied individually during four consecutive cycles was shown to resemble that of progesterone. in these animals, data were pooled according to stage of cycle on the basis of plasma progesterone concentrations. mean values for inhibin w ... | 1990 | 2212937 |
| extension of reproductive suppression by pheromonal cues in subordinate female marmoset monkeys, callithrix jacchus. | pheromonal signals from the dominant female marmoset monkey were implicated in maintaining the suppression of lh secretion and ovulation in socially subordinate females. when subordinate, and reproductively suppressed, female marmoset monkeys were removed from their group without scent contact with their dominant females, subordinate females in control group 1 (n = 8) and control group 2 (n = 5), ovulated 10.8 +/- 1.4 days and 10.4 +/- 0.8 days respectively (mean +/- s.e.m.) after separation. su ... | 1990 | 2250240 |
| an ultrastructural study of early chorionic villus formation in the marmoset monkey (callithrix jacchus). | the ultrastructural morphology of developing chorionic villi in the marmoset monkey (callithrix jacchus) placenta was studied in pregnant monkeys at known time intervals after ovulation. in samples obtained at 45 days after ovulation the mesoderm, which consists of primitive foetal blood vessels, is seen to extend down into cytotrophoblast columns. syncytiotrophoblast completely surrounds maternal blood vessels and both basal laminae and endothelial cells of maternal origin show signs of disorga ... | 1990 | 2305971 |
| the topology of the thalamo-cortical projections in the marmoset monkey (callithrix jacchus). | this paper addresses the question of a general topological principle of thalamo-cortical projections. in the lissencephalic primate brain of the common marmoset (callithrix jacchus), large injections of horseradish peroxidase were made in various parts of the neocortex. these injections were placed in different animals and hemispheres along various caudo-rostral and medio-lateral gradients. labelled cells in the thalamus were plotted and the labelling-zones resulting from several injections alon ... | 1990 | 2394218 |
| polyhalogenated dibenzo-p-dioxins and dibenzofurans and the immune system. 1. effects on peripheral lymphocyte subpopulations of a non-human primate (callithrix jacchus) after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd). | monoclonal antibodies were used to analyse the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) on peripheral lymphocytes from marmosets (callithrix jacchus) following injections of single low doses of tcdd. a reduction of the percentage and the total number of lymphocytes among the white blood cells was seen 3 weeks after a single administration of 300 ng tcdd/kg body wt, but not following 167 ng tcdd/kg or less. after treatment of marmosets with the single subcutaneous dose of 10 ng tcdd/ ... | 1990 | 2403285 |
| in vitro immortalization of marmoset cells with three subgroups of herpesvirus saimiri. | sequences within the rightmost 7 kilobases of the unique l dna of herpesvirus saimiri are required for oncogenicity of the virus. the same dna region has been found to be highly variable among different strains of herpesvirus saimiri. on the basis of this variability, herpesvirus saimiri strains were classified into groups a, b, and non-a, non-b. herpesvirus saimiri strains representing the three groups were used successfully for in vitro immortalization of phytohemagglutinin-activated, interleu ... | 1987 | 2822956 |
| dietary lipid modulation of myocardial beta-adrenergic mechanisms, ca2+-dependent automaticity, and arrhythmogenesis in the marmoset. | dietary lipid supplements high in either saturated fatty acids derived from sheep perirenal fat or polyunsaturated fatty acids (65% linoleic acid) derived from sunflower seed oil were fed to marmoset monkeys (callithrix jacchus) for 20 months. the effect of these long-term dietary lipid supplements on myocardial contractile function and their influence on responses to isoprenaline and external calcium concentration were examined using isolated papillary muscles and atria. isoprenaline potency wa ... | 1987 | 2444777 |
| long-term protection against argentine hemorrhagic fever in tacaribe virus infected marmosets: virologic and histopathologic findings. | tacaribe virus may represent a better alternative than attenuated strains of junin virus (jv) for immunization against argentine hemorrhagic fever (ahf) because of possible risk of persistent infection of disease associated with live, attenuated strains. callithrix jacchus marmosets, which suffer 100% mortality if inoculated with the pathogenic xj strain of jv, were used to evaluate possible tacaribe virus persistence, subclinical, or long-term disease and the duration of protection against chal ... | 1988 | 2832541 |
| differences in transneuronal transport of horseradish peroxidase conjugated wheat germ agglutinin in the visual system: marmoset monkey and guinea pig compared. | conjugates of the lectin wheat germ agglutinin with horseradish peroxidase have been described as effective transneuronal tracers in different neuronal systems of various mammalian species. here, the failure is described to detect any sign of transneuronal transport of the tracer in the visual system of adult marmoset monkeys (callithrix jacchus), in spite of heavy anterograde labeling in the primary visual centers after intravitreous injections. in contrast, in the brains of guinea pigs process ... | 1989 | 2473107 |
| glomerulonephritis in common marmosets infected with plasmodium brasilianum and epstein-barr virus. | plasmodium brasilianum causes chronic quartan malaria in the common marmoset callithrix jacchus, whereas epstein-barr virus (ebv) infection is followed by an infectious mononucleosis-like syndrome that resolves. we infected weanling marmosets with one or both of these pathogens. timing of the infections influenced outcome. six animals were simultaneously infected with both agents; four became seriously ill (with accompanying proteinuria and edema) and either died or were killed. histopathology i ... | 1988 | 2844917 |
| comparison of the metabolism and disposition of [3-14c]coumarin in the rat and marmoset (callithrix jacchus). | male sprague-dawley rats and marmosets were given a single oral 25 mg/kg dose of [3-14c]coumarin and the excretion of radioactivity in the expired air, urine and faeces monitored up to 96 h. excretion profiles were similar in both species with the bulk of the dose being excreted in the urine and faeces within 24 h. chromatographic analysis of 0-48 h urine samples revealed similar metabolic profiles with only small amounts of unchanged coumarin and very little 7-hydroxycoumarin. coumarin 7-hydrox ... | 1989 | 2493171 |
| developmental changes in luteinizing hormone/human chorionic gonadotropin steroidogenic responsiveness in marmoset granulosa cells: effects of follicle-stimulating hormone and androgens. | factors regulating lh/hcg responsiveness in primate granulosa cells were examined in the marmoset monkey (callithrix jacchus). granulosa cells were isolated and pooled from small antral (0.5-1.0 mm) and large preovulatory (greater than or equal to 2 mm) follicles from mid- to late follicular phase ovaries of cyclic marmosets. the cells from small and large follicles were cultured in serum-free medium for 48 h in the absence or presence of increasing concentrations of hcg (0.1-100 ng/ml) with or ... | 1989 | 2494036 |
| ascorbic acid in a new world monkey family: species difference and influence of stressors on ascorbic acid metabolism. | like other simian primates, the new world monkey callithrix jacchus, marmoset, and saguinus fuscicollis, tamarin, require ascorbic acid as an essential nutrient. for adult marmosets, a daily intake of 15 mg/kg metabolic body weight was found to be necessary to obtain a serum level above the kidney threshold. a survey of the serum ascorbic acid level of marmosets and tamarins in a breeding colony resulted in a vast divergence between the two species, indicating a higher ascorbic acid requirement ... | 1989 | 2497592 |
| heinz bodies do not modify the membrane characteristics of common marmoset (callithrix jacchus) erythrocytes. | the possibility was examined that the membrane function of erythrocytes obtained from healthy common marmosets (callithrix jacchus) was modified by the presence in the cells of heinz bodies. no significant differences were found in erythrocyte endogenous free malonyl dialdehyde (mda) or reduced glutathione (gsh) between normal human erythrocytes and marmoset erythrocytes containing heinz bodies. membrane fluorescent chromolipids, surface charge and thiol levels were similar in both species but a ... | 1989 | 2498578 |
| attenuated junin virus infection in callithrix jacchus. | twenty marmosets, male callithrix jacchus, were used during this study. fifteen of the marmosets were inoculated with 5,000 tcid50 of the attenuated xjc13 strain of junin virus by intramuscular route and five were left as uninoculated controls. animals were observed for a 420-day period. in order to carry out virologic, hematologic, serologic, and histologic studies the animals were bled and/or killed at different days post infection(pi). results obtained showed that the attenuated strain produc ... | 1985 | 2981980 |
| the mechanism of end-organ resistance to 1 alpha,25-dihydroxycholecalciferol in the common marmoset. | the common marmoset, a new world monkey, requires a large amount of cholecalciferol (110 i.u./day per 100g body wt.) to maintain its normal growth. in a previous report, we demonstrated that the circulating levels of 1 alpha, 25-dihydroxycholecalciferol [1 alpha,25(oh)2d3] in the marmosets are much higher than those in rhesus monkeys and humans, but the marmosets are not hypercalcaemic [shinki, shiina, takahashi, tanioka, koizumi & suda (1983) biochem. biophys. res. commun. 14, 452-457]. to comp ... | 1985 | 2988503 |
| experimental brugia pahangi and b. malayi infections of callitrichid primates. | the callitrichid primates, callithrix jacchus jacchus (the marmoset) and saguinus labiatus (the tamarin) were inoculated with infective larvae of brugia malayi and b. pahangi. microfilaraemia at low levels developed in 3 out of 4 c.j. jacchus infected with b. malayi and living or dead adult worms found in all 4. only one of 4 c.j. jacchus became microfilaraemic (mf + ve) when given b. pahangi and adults were found in two. of 4 s. labiatus given b. pahangi one became very lightly mf + ve and adul ... | 1989 | 2500478 |
| termination of pregnancy in common marmosets (callithrix jacchus) following administration of antiserum to chicken riboflavin carrier protein. | the presence of protein(s) which is immunologically and functionally similar to the well characterised avian riboflavin carrier protein has been demonstrated in female common marmosets during pregnancy. the protein(s) that interacts with [14c]riboflavin has an immunological homology to chicken riboflavin carrier protein. the termination of pregnancy in four out of six marmosets following administration of antiserum to chicken riboflavin carrier protein supports the hypothesis that vitamin carrie ... | 1989 | 2503615 |
| inoculation of new world primates with the human immunodeficiency virus. | the susceptibility of common marmosets and cotton-top tamarins to infection by hiv-2 in vivo was tested. one year and 19 months, respectively, post-inoculation, sera taken from three of four animals from each species are reactive for hiv-2 antibodies and hiv-specific nucleotide sequences were demonstrated in short-term cultures of pbl from two cotton-top tamarins. the animals remain in good health. | 1989 | 2503618 |
| a re-investigation of the behavioural effects of intracerebral injection in marmosets of cytopathic cerebrospinal fluid from patients with schizophrenia or neurological disease. | in experiments designed to investigate transmission, cerebrospinal fluid (csf) from patients with schizophrenia or neurological disease (huntington's disease) which had been found to induce a cytopathic effect (cpe) in human embryonic fibroblast cell culture was injected intracerebrally into common marmosets. behavioural observations were made on the animals during a period of 2 1/2 years prior to injection and for 2 1/2 years after injection. in an earlier study (baker et al. 1983 b) we found t ... | 1989 | 2503849 |
| establishment and characterization of a chronic infectious mononucleosislike syndrome in common marmosets. | epstein-barr virus (ebv) was inoculated into two species of marmosets. successful infection was established in the majority of the animals of one species, callithrix jacchus, as evidenced by the development of high, persistent levels of antibody against virus-specific capsid and early nonstructural proteins. antibodies also were produced against the major membrane antigen and, in some animals, against ebv nuclear antigen (ebna) 2 but not against ebna 1. this is the antibody profile normally note ... | 1986 | 3011982 |
| [ultrastructure of the gastrointestinal epithelium in the marmoset (callithrix jacchus)]. | the epithelium of the stomach and intestine of one and three days old as well as adult marmosets was investigated using transmission electron microscopy and was compared with already existing data of man and the laboratory rodents, rat, mouse and guinea-pig. on postnatal day (pd) 1, the enterocytes possessed an inframicrovillous membrane system and giant lysosomes which were absent in adult marmosets whereas the surface and glandular epithelial cells of the stomach showed all structures which we ... | 1989 | 2505460 |
| shortening of luteal phase in common marmosets by sheep ovarian follicular fluid peptide. | a low molecular weight peptide has been partially purified from sheep follicular fluid. it inhibited fsh binding to granulosa cells from ovarian follicles of common marmosets (callithrix jacchus). when injected into cycling marmosets during the follicular phase, it reduced the area under the curve (auc) of circulating progesterone. the peptide also shortened the luteal phase in all marmosets during the treatment cycle compared to the pretreatment control cycle. these results indicate that the ov ... | 1989 | 2505972 |
| fall in coronary heart disease mortality in u.s.a. and australia due to sudden death: evidence for the role of polyunsaturated fat. | epidemiological studies have been reviewed which provide suggestive evidence of an association between the fall in coronary heart disease mortality in the u.s.a and australia since 1967, characterized by a fall in sudden deaths, to the increase in polyunsaturate fat consumption that has occurred in both countries since 1960. this association led directly in the same institution to carefully designed experimental studies undertaken in the rat, and a non-human primate, the marmoset (callithrix jac ... | 1989 | 2506314 |
| a new transmissible viral hepatitis of marmosets and tamarins. | callitrichid hepatitis (ch) is a newly recognized, acute, fatal, epizootic disease of new world primates in the family callitrichidae. since 1980, 12 outbreaks of ch have occurred in us zoos, involving several callitrichid species including the endangered golden lion tamarin (leontopithecus rosalia). ch was experimentally transmitted to common marmosets via a bacteria-free filtrate of liver from a naturally infected tamarin. all three inoculated marmosets developed an acute fatal disease with th ... | 1989 | 2509570 |
| fate of recombinant human renin administered exogenously to anesthetized monkeys. | highly purified recombinant human renin (rh-renin), synthesized by chinese hamster ovary cells, was labeled with iodine-125 and was given intravenously to pentobarbital-anesthetized common marmosets (callithrix jacchus) to study the fate of the circulating renin. specific anti-rh-renin antiserum was used to identify the 125i-rh-renin. plasma disappearance of the exogenously administered 125i-rh-renin in marmosets (n = 6) showed two exponential components, with a half-life of 12.1 +/- 1.9 minutes ... | 1988 | 3049339 |
| control of inhibin production by primate granulosa cells. | in-vitro data from experiments on rats implicate granulosa cells as primary sites of hormone-dependent ovarian inhibin biosynthesis, but no equivalent data exist for primates. we have used the common marmoset (callithrix jacchus) to investigate inhibin biosynthesis in primate granulosa cells in vitro and to determine its relationship to preovulatory follicular development. to relate the production of immunoactive inhibin to follicular maturity, we studied primary granulosa cell cultures from fol ... | 1989 | 2509620 |
| bone in the marmoset: a resemblance to vitamin d-dependent rickets, type ii. | the common marmoset, a new world monkey, requires a large amount of vitamin d3 to maintain its normal growth. this monkey is reported to have an end-organ resistance to 1 alpha,25-dihydroxyvitamin d3 (1 alpha,25(oh)2d3). in this study, the bone morphology of marmosets fed a high vitamin d3 diet (intake of vitamin d3, 110 iu/day/100 g of body weight) was compared by x-ray and histological examinations with that of rhesus monkeys (old world monkey) fed a normal diet (intake of vitamin d3, 5 iu/day ... | 1986 | 3089562 |
| sulphoxidation of s-carboxymethyl-l-cysteine in the rhesus monkey (macaca mulatta), cynomologus monkey (macaca fascicularis), african green monkey (cercopithecus aethiops) and the marmoset (callithrix jacchus). | the metabolic pathways giving rise to the urinary metabolites of s-carboxymethyl-l-cysteine have been identified for the rhesus, cynomologus, african green and marmoset species of monkey. the formation of a sulphoxide metabolite from the sulphide precursor is a reaction important in these species. the metabolic profile displayed by the marmoset was distinct from the three old world species, with the rhesus and cynomologus being similar to man. | 1986 | 3089678 |
| [mother to child transmission of human t cell leukemia virus type-1]. | infection of htlv-1 during childhood may be the most probable cause of leukemogenesis of atl. the possibility of mother to child transmission of htlv-1 was studied. our epidemiological investigation disclosed that almost all mothers of htlv-1 carrier children were positive for anti-htlv-1 antibody and children born from carrier mothers showed statistically higher positive rate for anti-htlv-1 antibody than control groups. a large number of htlv-1 positive lymphocytes were detected in the milk fr ... | 1989 | 2512396 |
| milk-borne transmission of htlv-i as a major route in the endemic cycle. | mother-to-child transmission of htlv-i as a major route in the endemic cycle of htlv-i was established by epidemiologic evidence that (1) 22% (17/78) of children of htlv-i carrier mothers were themselves carriers, in contrast to approximately 1% of the young age population of the same area, (2) more than 95% (23/24) of mothers of carrier children were themselves carriers, and (3) the product of the prevalence of carrier mothers and the incidence of carriers in children born to them corresponded ... | 1989 | 2514566 |
| blockade of the oestrogen-induced lh surge in the ovariectomized common marmoset (callithrix jacchus) by an lhrh antagonist. | six long-term ovariectomized adult marmoset monkeys were treated at 0 h with 35 micrograms oestradiol benzoate s.c. to induce an lh surge. they were also treated with detirelix (an lhrh antagonist) at 0 h, 12 h and 24 h (exp. 1), or at 0 h and 24 h (exp. 2) at a dose of 300 micrograms/kg s.c., or received the detirelix vehicle alone at 0 h, 12 h and 24 h (exp. 3). all animals received the three treatments, with at least 4 weeks between experiments. blood samples were collected at 0 h and at 6-12 ... | 1989 | 2539474 |
| changing responsiveness of luteal cells of the marmoset monkey (callithrix jacchus) to luteotrophic and luteolytic agents during normal and conception cycles. | dispersed marmoset luteal cells were incubated for 2 h and progesterone production measured after exposure to hcg, cloprostenol, dibutyryl camp, pgf-2 alpha, pgf-2, adrenaline or melatonin. the cells were studied on days 6, 14 and 20 after ovulation in conception and non-conception cycles. luteal cells from day 14 non-pregnant marmosets were compared with human luteal cells taken in the mid-luteal phase. all the treatments stimulated progesterone production including cloprostenol, which is luteo ... | 1989 | 2560061 |
| tissue specific differences in the fatty acid composition of the marmoset monkey (callithrix jacchus). | 1. the possible relationship between the fatty acid composition of the adipose tissue of the marmoset monkey (callithrix jacchus) and its dietary lipid intake was examined after a long-term feeding trial. 2. only the proportions of stearic and linoleic acid in the adipose tissue were similar to those in the diet. the proportions of all other saturated and unsaturated fatty acid components were significantly different thus greatly reducing the potential value of this relationship in the marmoset. ... | 1989 | 2565781 |
| stereoselective reversal of mptp-induced parkinsonism in the marmoset after dermal application of n-0437. | the selective dopamine d-2 receptor agonist n-0437 produced a rapid and dose-dependent reversal of motor deficits lasting 90-120 min following i.p. or oral administration of the racemate to mptp-treated common marmosets. in contrast, topical application of (+/-)-, (+)- or (-)-n-0437 to the skin of mptp-treated animals did not alter locomotor activity in the initial 4 h although other motor disabilities were reduced. however, 24 h following application of the racemate or the (-) enantiomer both l ... | 1989 | 2572426 |
| desenkephalin-gamma-endorphin is an antagonist of the hyperactivity response induced by infusion of dopamine into the nucleus accumbens of rat and ventral striatum of marmoset. | the ability of desenkephalin-gamma-endorphin (de gamma e; org5878) to antagonise a raised limbic dopamine function was investigated in the rat and common marmoset. dopamine was infused for 13 days directly into the nucleus accumbens of the rat and ventral striatum of the marmoset and increased locomotor activity. such increases in both the rat and marmoset were antagonised by the subcutaneous injection of de gamma e, administered in a range 10-500 micrograms/kg (t.i.d.), during the 13 day period ... | 1989 | 2574424 |
| immunohistochemical distribution and colocalization of regulatory peptides in the carotid body. | current investigations on the immunohistochemical occurrence and co-occurrence of biogenic polypeptides in the mammalian carotid body were reviewed and extended by our own recent findings. the family of chromogranins and related peptides in glomus cells appears to have a widespread interspecies distribution, whereas other peptides investigated occur in a species-specific pattern. immunoreactivity to antisera against opioids, which derive from the proenkephalin sequence, appears to be present in ... | 1989 | 2671303 |
| herpesvirus ateles immortalizes in vitro a cd3+cd4+cd8+ marmoset lymphocyte with nk function. | herpesvirus ateles, nonpathogenic in its natural host, the spider monkey, induces a fatal lymphoproliferative syndrome in a variety of new world primate species. whereas the closely related new world primate virus herpesvirus saimiri immortalizes in vitro common marmoset lymphocytes that express a tcr and phenotypically are cd4-cd8+nkh1+, we now show that h. ateles-immortalized marmoset lymphocytes are cd3+ and cd4+. furthermore, these cd4+ lymphocytes coexpress cd8 and nkh1. the nk function of ... | 1988 | 2828471 |
| expression of c-type viral particles at implantation in the marmoset monkey. | type c rna retroviral particles have been observed budding from the plasma membrane of syncytiotrophoblast during a study of embryo implantation in the common marmoset (callithrix jacchus). these viral particles appear in profusion at the interface of syncytiotrophoblast with cytotrophoblast. they appear to be a non-infective, endogenous viral component of the host genome, although the precise role of the c-type virus in this context is unclear at present. such viral particles have been reported ... | 1988 | 2836475 |
| [cytochemical studies of hydrolases in the genitalia of female marmosets (callithrix jacchus) and rats]. | | 1985 | 2862661 |
| tissue activities of enzymes of diagnostic interest in the marmoset and rat. | the activities of enzymes of diagnostic interest were investigated in the liver, heart, kidney and muscle of the marmoset (callithrix jacchus) and the rat. methods of tissue extraction which gave maximal enzyme activity were used and comparison between the species showed some major differences. ast, ldh and gdh showed a similar distribution in both species but icdh activity was much higher in the rat heart than in any other rat or marmoset organ. alp, lap and ggt were present in much higher acti ... | 1988 | 2905366 |
| purification and properties of cytochrome p-450 from liver microsomes of phenobarbital-treated marmoset monkeys (callithrix jacchus). | one form of cytochrome p-450 from phenobarbital-induced marmoset liver was purified to apparent electrophoretic homogeneity and compared with the major inducible form isolated from rat liver. whereas spectral properties and molecular weights, as well as catalytic activities towards aminopyrine and ethylmorphine n-demethylation are quite similar, rates of o-dealkylation with enzymes from the two species are considerably different. while ethoxycoumarin deethylation for the marmoset cytochrome is a ... | 1989 | 2919406 |
| lymphocyte subsets in the young and aging marmoset (callithrix jacchus). | t lymphocytes were studied in healthy young and old marmosets (callithrix jacchus). data indicate that monoclonal antisera to human t lymphocyte antigens can be used to identify these cells in marmosets. total t and suppressor t cells were lower in the older group; there were no differences in helper t or in b cells. helper/suppressor ratios (t4/t8) were increased in the older group. thus, immune system alternations with aging and/or immune deficiency syndromes may be studied in this animal mode ... | 1986 | 2948018 |
| oral transmission of human t-cell leukemia virus type-i into a common marmoset (callithrix jacchus) as an experimental model for milk-borne transmission. | to obtain experimental support for possible milk-borne infection of human t-cell leukemia virus type-i (htlv-i), short-term-cultured viral antigen-positive lymphocytes obtained from peripheral blood of adult t-cell leukemia lymphoma complex (atll) patients were inoculated into the oral cavity of two adult common marmosets (callithrix jacchus) in amounts comparable to those of htlv-i-carrying cells fed to a baby in the milk of seropositive mothers. one of the animals seroconverted 2.5 months afte ... | 1985 | 2991061 |
| nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization. | herpesvirus saimiri l-dna sequences between 0.0 and 4.0 map units (4.5 kilobase pairs) are required for oncogenicity; these sequences are not required for replication of the virus. to investigate the basis for the lack of oncogenicity of mutants with deletions in this region and to study the function of this region, we developed a reliable system for in vitro immortalization by herpesvirus saimiri. in contrast to peripheral blood lymphocytes from cotton-top tamarins (saguinus oedipus) and owl mo ... | 1986 | 3003401 |
| chronic toxicity of 3,4,3',4'-tetrachlorobiphenyl in the marmoset monkey (callithrix jacchus). | cotton top marmoset monkeys (callithrix jacchus) were orally dosed with 3, 1, 0.1 or 0 mg 3,4,3',4'-tetrachlorobiphenyl (tcb)/kg body weight twice per week for 18-23 weeks. severe toxicity occurred in the highest dose group. clinical signs of toxicity were a rapid decrease in body weight, alopecia, abnormal nail growth, nodular enlargement of the nipple area and scaly skin. haematological analysis of peripheral blood revealed mild leukocytosis and anemia. biochemical alterations observed were el ... | 1988 | 3124295 |
| oral infection of a common marmoset with human t-cell leukemia virus type-i (htlv-i) by inoculating fresh human milk of htlv-i carrier mothers. | to obtain definitive evidence that milk-borne infection plays a critical role in the endemy or mother-to-child transmission of human t-cell leukemia virus type-i (htlv-i), we inoculated concentrated fresh human milk cells obtained from htlv-i carrier mothers into the oral cavity of a common marmoset (callithrix jacchus). twenty-eight milk samples were collected (5-10 ml each) from 17 carrier mothers in the first week after delivery. cells in the milk were centrifuged down and resuspended in 1/10 ... | 1985 | 3005206 |
| rapid diagnosis and management of parainfluenza i virus infection in common marmosets (callithrix jacchus). | during 1983 a severe episode of respiratory infection occurred in a marmoset colony at these laboratories. of 91 marmosets, 69 showed clinical signs of disease, one died and nine were so ill that euthanasia was necessary. eight were examined post mortem and all showed consolidation of the lungs. laboratory studies were carried out in an attempt to establish the cause of the outbreak and an interstitial pneumonia was found in seven animals which were examined histologically. direct electron micro ... | 1986 | 3009965 |
| identification of the main gestagen metabolite in marmoset (callithrix jacchus) urine by nmr and ms spectroscopy. | hydroxypregnanolone is the most abundant progesterone metabolite in the urine of marmoset monkeys (callithrix jacchus). the substance is excreted as conjugate. the concentration of this steroid may be monitored by high performance, thin layer chromatography and postchromatographic derivatization. hydroxypregnanolone was purified and subsequently identified by nmr spectroscopy and gas chromatography/mass spectroscopy. the exact chemical structure is 5 alpha-pregnane-3 alpha, 7 alpha-diol-20-one. | 1988 | 3130485 |
| herpesvirus saimiri strain 11 immortalizes a restricted marmoset t8 lymphocyte subpopulation in vitro. | herpesvirus saimiri induces a fatal lymphoproliferative syndrome in a variety of new world primate species. we now show that cell lines derived from pbl of the common marmoset by in vitro-immortalization with h. saimiri strain 11 represent a remarkably restricted lymphocyte population. these cell lines have nk cell function, phenotypically express both suppressor/cytotoxic (t8) and nk cell (nkh1)-associated antigens, and express a t cell receptor. this subpopulation of lymphocytes is a very mino ... | 1986 | 3018122 |
| therapeutic effect of the antiviral agent ribavirin in junín virus infection of primates. | in order to assess the effect of the antiviral ribavirin on the course of junín virus infection in callithrix jacchus, seven inoculated monkeys were treated with 15 mg of the drug, twice a day, starting 6 days after infection when all animals were viremic. the three untreated controls showed typical signs of junín virus infection at 14 days pi and their mean time of death was 18 days. in contrast, no signs of illness were detected in ribavirin-treated animals until 24 days pi, when marmosets sho ... | 1986 | 3023541 |
| characterization of colonic cellular glycoconjugates in colitis and cancer-prone tamarins versus colitis and cancer-resistant primates. | differences in colonic secretory glycoconjugates (ie, mucin) between normal and ulcerative colitis-prone patients have been noted. similar differences may occur in a corresponding primate model, the cotton-top tamarin (ctt), saguinus oedipus, a new world monkey which suffers from spontaneous chronic colitis and colon cancer. lectin reagents were used to characterize and compare colonic cell surface, cytoplasmic, and secretory glycoconjugates of 9 clinically healthy cotton-top tamarins, 7 colitis ... | 1988 | 3132857 |
| protection of junín virus-infected marmosets by passive administration of immune serum: association with late neurologic signs. | argentine hemorrhagic fever (junín virus) is a human viral disease for which immune therapy proves effective, though a late neurologic syndrome is occasionally associated with the treatment. we attempted to determine in the infected marmoset callithrix jacchus whether immune therapy leads to protection and/or cns damage. fifteen c jacchus were inoculated with 10(3) tissue culture infectious dose 50% (tcid50) of the xj strain of junín virus. on day 6 post infection (pi), 12 primates were treated ... | 1987 | 3025358 |
| successful infection of the common marmoset (callithrix jacchus) with human varicella-zoster virus. | the common marmoset, callithrix jacchus, can be infected with human varicella-zoster virus (vzv), both wild-type strain kmcc and attenuated vaccine strain oka/merck. infection was accomplished with either whole-cell-associated or cell extract vzv by combined oral-nasal-conjunctival application and was characterized by substantial and persistent anti-vzv antibody responses. the infectivity of vzv for marmosets was destroyed by treatment of inocula with heat or uv light. diluted inocula with as fe ... | 1987 | 3041014 |
| serum protein electrophoretic patterns of the marmoset, callithrix jacchus. | three electrophoretic procedures were used to separate protein fractions of marmoset serum. the albumin of marmoset serum migrated further than that of human serum with all three procedures and the number and size of the globulin fractions differed with species and with procedure. | 1986 | 3088068 |
| polymorphism of visual pigments in a callitrichid monkey. | microspectrophotometric measurements of visual pigments have been obtained for a large sample of new world monkeys of the species callithrix jacchus jacchus. these animals exhibit a polymorphism of visual pigments. the rods (lmax 499 nm) and the short-wave receptors (lmax 423 nm) appear to be common to all animals but individuals differ in the number and spectral position of pigments in the green-yellow spectral region. the latter pigments cluster near 545, 559 and 567 nm. male monkeys draw one ... | 1988 | 3143179 |
| afferent connections of the substantia innominata/basal nucleus of meynert in carnivores and primates. | afferent connections to the substantia innominata/nucleus basalis complex of monkeys and cats were traced by using the method of retrograde transport of horseradish peroxidase (hrp). altogether ten injections of hrp were performed in four monkeys (saimiri sciureus, callithrix jacchus, galago senegalensis) and in four cats, with either vertical or oblique needle approaches. the entire brains excluding the olfactory bulbs and the cerebellum were then screened for labeled neurons. in both monkey an ... | 1986 | 3093564 |
| quantitative changes in morphological parameters in the developing visual cortex of the marmoset monkey. | several quantitative morphological parameters were measured during postnatal development in area 17 of the marmoset monkey (callithrix jacchus). in a series of 14 animals, at ages from birth to adulthood, we studied changes in the thickness, surface area and volume of area 17, as well as the neuronal and glial numerical densities, and total numbers. we found evidence for a rapid increase in thickness, area and volume, culminating between 6 weeks and 6 months postnatally, and then decreasing. the ... | 1986 | 3094833 |
| embryotoxic effects of thalidomide derivatives on the non-human primate callithrix jacchus; 3. teratogenic potency of the em 12 enantiomers. | the teratogenic potencies of the enantiomers of 2-(2,6-dioxopiperidine-3-yl)-phthalimidine ( = em 12), a teratogenic thalidomide analogue, were investigated in callithrix jacchus, a primate very sensitive to the teratogenic action of this thalidomide analogue. the results indicate that the s-(-)-form of em 12 is clearly more teratogenic than the r-(+)-form. the interpretation of the studies designed to evaluate stereo-selective differences in the teratogenicity of the enantiomers becomes difficu ... | 1988 | 3196154 |
| a backpack system for long-term osmotic minipump infusions into unrestrained marmoset monkeys. | a backpack system is described whereby osmotic minipumps are used to infuse gonadotrophin-releasing hormone (gnrh) subcutaneously in a pulsatile manner into infertile socially subordinate female marmoset monkeys (callithrix jacchus jacchus). this procedure enables long-term infusion of gnrh without the necessity of repeated subcutaneous implantation of pumps and gnrh reservoirs. the backpack and cannulae system is inexpensive and can be constructed from commonly available materials. the gnrh tre ... | 1986 | 3095582 |
| [comparative scanning and transmission electron microscopy studies of the ependyma of the central canal in the spinal cord of primates. i. electron optical image of the ependyma in the central canal of the spinal cord of the callithrix monkey (callithrix jacchus, linné 1758)]. | the ependyma lining the central canal of the spinal cord of adult males and females monkey, callithrix jacchus, was examined by scanning and transmission electron microscopy. the cross section of the lumen of the central canal are round, oval, or triangular. light and dark ependymal cells, depending on the density of the cytoplasm, were found. the light ependymal cells are fewer than the dark cells. the ependyma cytoplasm contained numerous mitochondria, filamentous structures, one or more well- ... | 1986 | 3098621 |
| short-term toxicity study of 4-dimethylaminoazobenzene in marmosets. | the marmoset, a small non-human primate, has rarely been used in toxicological studies. a short-term toxicity study was performed on common marmosets (bw = 330 +/- 32 g). fifteen male marmosets received oral administration of dab at a dose level of 56 mg/kg/day and 4 control animals received corn oil alone for a period of 15 days. hematological, biochemical, histopathological and bone marrow examinations were carried out on the 5th, 10th and 15th day of treatment. body weight decreased continuou ... | 1986 | 3102751 |
| effects of variable linoleate intake on aortic pgi2-like activity and fatty acid composition: difference between rat and marmoset (callithrix jacchus). | two animal species, the laboratory rat and a non-human primate (the common marmoset) were compared with respect to the influence of dietary lipid supplementation on both fatty acid composition and prostanoid synthetic capacity of aorta. standard chow (ref. diet) was supplemented (12% w/w) with either sheep fat (sf) or sunflower seed oil (sso). differences were apparent in the aortic phospholipid fatty acids from both animal models, as a result of the diet, although the type and the extent of cha ... | 1986 | 3103139 |
| elevated urinary excretion of beta-aminoisobutyric acid and exposure to inorganic lead. | beta-aminoisobutyric acid (beta-aib), a normal degradation product of thymine, a constituent of dna and, to a lesser extent, of transfer rna, is excreted in low levels in human urine. we found that a group of iron workers occupationally exposed to inorganic lead excreted high levels of urinary beta-aib. elevated urinary excretion of beta-aib was also observed in marmosets, callithrix jacchus, that received lead acetate in drinking water. our results suggest that increased urinary excretion of be ... | 1987 | 3579372 |
| in vivo formation of metabolites of prostaglandins i2 and i3 in the marmoset monkey (callithrix jacchus) following dietary supplementation with tuna fish oil. | recent studies have shown that ingestion of eicosapentaenoic acid (epa) in man results in the formation of 'trienoic' prostanoids which amy partly explain the potent antithrombotic/antiatherogenic properties of long-chain polyunsaturated n-3 fatty acids (pufas). however, endogenous formation of cyclooxygenase metabolites of epa has not been demonstrated in an animal model, and in vitro studies indicate a clear species difference in the conversion of epa to pgi3. thus, in the present study, the i ... | 1989 | 2659082 |
| influence of dietary fats on blood coagulation and prostaglandin production in the common marmoset. | common marmosets were fed a standard marmoset diet (ref) or diets supplemented with 12% (wt/wt) sunflower seed oil (sso) or sheep fat (sf) for a period of 90 weeks. the values for coagulation indices, clotting time, and russel viper venom time were consistent with decreased thrombotic tendency of platelets from animals on the sso diet relative to the low fat, ref diet animals, while an increased tendency to thrombosis was observed with sf-fed marmosets. the sso- and sf-supplemented marmosets sho ... | 1987 | 3107535 |
| animal models of mycoplasma genitalium urogenital infection. | male and female animals were inoculated urogenitally with mycoplasma genitalium, recovered originally from men with nongonococcal urethritis. mice, hamsters and male rhesus monkeys (macaca mulatta) were resistant. male cynomolgus monkeys (macaca fascicularis) were not as sensitive as male chimpanzees (pan troglodytes): 9 of 11 developed an obvious genital tract infection, some shedding organisms for more than 18 weeks. m. genitalium was recovered from the blood of two of them when large numbers ... | 1987 | 3667225 |
| mercapturic acid formation in the marmoset (callithrix jacchus). | benzylmercapturic acid is a major metabolite of [methylene-14c]benzyl chloride in the marmoset, as in the rat. the excretion of the minor metabolites benzylmercapturic acid sulphoxide and benzylcysteine accounted for a greater proportion of the dose than in the rat. excretion of hippuric acid as a metabolite of benzyl chloride was variable in the marmoset. acetylation of s-benzyl- and s-pentyl-l-cysteine to the corresponding mercapturic acids was extensive in the marmoset. trace amounts of the s ... | 1986 | 3751115 |
| active immunization against renin in normotensive marmoset. | primate renins (human and monkey) are very similar. we used pure human renin to immunize marmosets (callithrix jacchus) and thereby produce a chronic blockade of the renin-angiotensinogen reaction. after a control period of 2 months, five male marmosets, on their usual sodium-poor diet, were immunized against pure human renin by three subcutaneous injections of 30 micrograms each, with complete and then incomplete freund's adjuvant. three marmosets were injected with adjuvant only and served as ... | 1987 | 3108891 |
| determination of ovulation and pregnancy in the marmoset (callithrix jacchus) by monitoring of urinary hydroxypregnanolone excretion. | in callithrix jacchus the urinary excretion of hydroxypregnanolone (5 alpha-pregnane-3 alpha, 7 alpha-diol-20-one) shows a luteal rise during the ovulatory cycle. this progesterone metabolite can therefore be used as an indication of ovulation, implantation, and subsequently for the persistence of the pregnancy. the excretion can be monitored by high performance thin-layer chromatography (hptlc) and postchromatographic derivatization after enzymatic hydrolysis of the conjugate. profiles of urina ... | 1987 | 3112406 |
| rats and marmosets respond differently to serotonin agonists and antagonists. | the actions of the serotonin precursor 5-hydroxytryptophan (5-htp), the agonist 5-methoxy-n,n-dimetyltryptamine (meodmt) and quipazine (qpz) and the antagonists cyproheptadine, methysergide and metergoline, were studied in the rat and in the common marmoset (callithrix jacchus). the precursor and agonists elicited head shakes, forepaw padding, splayed hindlimbs, tremor and straub tail in the rat. however, head shakes were not observed after meodmt and straub tail was not observed after qpz. carb ... | 1987 | 3114802 |
| the measurement of ethylenethiourea and ethyleneurea in the rat and common marmoset callithrix jacchus after zineb (zinc ethylenebisdithiocarbamate) dosing. | the metabolism of the fungicide zineb, (zinc ethylenebisdithiocarbamate), has been studied in the rat and the marmoset. 2. it was found in both species that a relatively large proportion (21-22%) of the original zineb administered was detectable in the excreta as ethylenethiourea (etu) a known mutagen, teratogen and carcinogen. 3. a further proportion (2-5%) was determined to be ethyleneurea which is a metabolite of etu. 4. results of comparative experiments in marmosets revealed that etu was ph ... | 1987 | 3114968 |
| colonic mucin composition in primates. selective alterations associated with spontaneous colitis in the cotton-top tamarin. | heterogeneity of colonic mucin glycoprotein was examined in rectal mucosal biopsy specimens from a variety of primate species (saguinus oedipus, n = 18; macaca mulatta, n = 2; macaca fascicularis, n = 2; aotus trivirgatus, n = 2; saimiri sciureus, n = 2; and callithrix jacchus, n = 2). after initial separation of radiolabeled mucin and nonmucin glycoproteins solubilized from mucosal biopsy specimens, at least five labeled mucin components were found in monkey rectal mucosa in contrast to the six ... | 1985 | 3917260 |
| partial purification and characterization of chorionic gonadotrophin in plasma and in culture medium of trophoblast cells from the marmoset monkey (callithrix jacchus). | a biologically active gonadotrophin has been purified from the media of long-term cultures of trophoblast cells of the common marmoset monkey by a combination of precipitation and chromatography. marmoset chorionic gonadotrophin (cg) is a glycoprotein which binds concanavalin a and wheat germ agglutinin. the protein purified from culture media exists as several isoelectric species with pi in the range ph 3.5-4.5. on gel filtration it eluted with an apparent molecular weight of 68-72,000 but on p ... | 1987 | 3116232 |
| difference in serum ascorbate in two species of callithricidae. | in one species each of the subfamilies marmosets and tamarins of the new world monkey family callithricidae, serum levels of ascorbic acid were compared. although the feeding regimen had been the same for both species for several years, the average concentration of serum ascorbate in the tamarins saguinus fuscicollis (n = 21; 0.54 +/- 0.29 mg/100 ml) was only one-fifth that of the marmosets callithrix jacchus (n = 19; 2.56 +/- 1.07 mg). | 1987 | 3119508 |
| characteristics of trophoblastic tissue derived from in vitro culture of preimplantation embryos of the common marmoset monkey. | the features of trophoblastic tissue derived from the in vitro culture of marmoset monkey embryos have been described. long-term trophoblast cultures (in excess of three years in one case) were established from the primary trophoblast monolayer of four of 38 embryos; division of one of these embryos produced two long-term cultures. the trophoblast cells retained their ability to synthesize and secrete chorionic gonadotrophin (cg) during maintenance in vitro and were capable of prolonging the lut ... | 1987 | 3120174 |
| plasmodium brasilianum in the common marmoset callithrix jacchus. | chronic quartan malarial infection has been established in the common marmoset (callithrix jacchus). plasmodium brasilianum from a douroucouli monkey (aotus trivirgatus) was used to infect splenectomized twin animals, passed to an intact animal, and then to 4 other intact adults, 2 pairs of twins. in 2 of the 4 latter animals there was continuing patency with parasitaemias of less than or equal to 0.5% parasitized erythrocytes for 30 weeks. the other 2 had lower initial levels of parasitaemia; i ... | 1985 | 3925423 |
| ultrastructure and hydrolase cytochemistry of the developing marmoset yolk sac. | yolk sacs from callithrix jacchus were investigated light and electron microscopically as well as by qualitative light microscopic enzyme histochemistry on days 35 to 126 of gestation. the thin yolk sac wall of the early stages (day 35-41) consists of the cuboid, endodermal epithelium, the mesothelium of the exocoelom and some interposed blood vessels. the inner endodermal surface is rather smooth. at later stages, the epithelium becomes highly prismatic and forms folds which are lined by a mese ... | 1985 | 3929647 |
| connections of the primary auditory cortex in the common marmoset, callithrix jacchus jacchus. | the afferent and efferent connections of the primary auditory cortex (ai) of common marmosets were traced following small injections of wheat germ agglutinin conjugated with horseradish peroxidase (wga-hrp) made at best frequency (bf)-defined sites in the ai. after the injections the animals remained anesthetized for 15-23 hours; they were then perfused transcardially with fixative and the brains were processed for wga-hrp reaction product. examination of the disposition of labelled material rev ... | 1988 | 3128585 |
| induction of luteal regression in the marmoset monkey (callithrix jacchus) by a gonadotrophin-releasing hormone antagonist and the effects on subsequent follicular development. | doses of 100 or 200 micrograms of a novel gnrh antagonist ([n-acetyl-d beta na11-d-pcl-phe2-d-phe3-d-arg6-phe7-arg8-d-ala10]nh2 gnrh) (4 animals/dose) were administered on days 10/11 of the luteal phase and induced a marked suppression of circulating bioactive lh and progesterone concentrations within 1 day of treatment (p less than 0.01). thereafter, progesterone concentrations remained low or undetectable until after the next ovulation. similar results were obtained when 200 micrograms antagon ... | 1988 | 3129559 |
| factors influencing follicle-stimulating hormone-responsive steroidogenesis in marmoset granulosa cells: effects of androgens and the stage of follicular maturity. | preovulatory changes in the steroidogenic function of primate granulosa cells were studied using the cyclic marmoset (callithrix jacchus) as a model. antral follicles (greater than or equal to 0.5 mm diameter) were dissected from mid-late follicular phase ovaries (7 days after prostaglandin-induced luteolysis) and classified by diameter as small (0.5-1.0 mm), medium (1.1-1.9 mm) or large (greater than or equal to 2.0 mm). granulosa cells from follicles in each size category were isolated and poo ... | 1988 | 3131124 |
| the acute toxicity of sarin in marmosets (callithrix jacchus): a behavioral analysis. | in marmosets, the clinical signs of poisoning following the administration of sarin and the effects of sarin upon performance in three behavioral test models were investigated. the sensitivity of marmosets to the lethal action of sarin was shown to be greater than that of rodent species and rabbits but very similar to that of the rhesus monkey. doses of sarin ranging from 33 to 55% ld50, resulting in erythrocyte acetylcholinesterase inhibitions of 88% or more, were shown to disrupt the performan ... | 1985 | 3937760 |
| plasmodium vivax malaria in the common marmoset, callithrix jacchus: adaptation and host response to infection. | infection with plasmodium vivax was established in splenectomized callithrix jacchus marmosets by inoculation of parasitized blood from aotus trivirgatus carrying the vietnam palo-alto line of p. vivax. subsequent blood passage through intact marmosets resulted in higher peak parasitaemias (about 1% of red cells infected) and the loss of stainable schüffner's dots in infected cells. primary infections with the adapted line were patent for 74 days or more, and induced both a substantial antibody ... | 1988 | 3131721 |
| cellular aspects of pre-ovulatory folliculogenesis in primate ovaries. | according to current concepts of pre-ovulatory folliculogenesis in primate ovaries, each growing follicle has a 'threshold' requirement for stimulation by fsh which must be met if it is to enter the oestrogen-secretory phase of pre-ovulatory development. until recently, our understanding of the intra-follicular mechanisms underlying fsh action on granulosa cells was based largely on information from non-primate laboratory animals, mainly polyovulators such as rats. the present paper describes st ... | 1988 | 3134394 |
| metabolism and tissue distribution of tobacco-specific n-nitrosamines in the marmoset monkey (callithrix jacchus). | three male marmoset monkeys (callithrix jacchus) were injected i.v. with the tobacco-specific carcinogen [2'-14c]n'-nitrosonornicotine (nnn) (20.3 mumol/kg body weight) or [carbonyl-14c]4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (nnk) (18.8 or 420 mumol/kg body weight). they were sacrificed 4 h later. tissue distribution was studied in two monkeys by whole-body autoradiography and by computer-assisted densitometric analysis of the autoradiograms. the autoradiograms showed a high level of rad ... | 1985 | 4053274 |
| social status controls lh secretion and ovulation in female marmoset monkeys (callithrix jacchus). | the suppression of ovulation in subordinate female marmosets was associated with suppressed pituitary lh secretion and reduced pituitary lh response to gonadotrophin-releasing hormone (gnrh). in subordinate females, basal plasma lh concentrations were commonly below 2 iu/l (n = 5) (maximum 10.7 iu/l). plasma oestrogen concentrations were similarly low (maximum 0.62 nmol/l) and plasma progesterone concentrations of below 30 nmol/l confirmed the anovulatory condition. this infertility condition wa ... | 1988 | 3134506 |
| [locomotive behavior of the monkey callithrix jacchus erxleben, 1777, with special reference to the hand function]. | | 1972 | 4629602 |
| studies on experimental bacteremia and pyelonephritis in the marmoset (callithrix jacchus). | | 1968 | 4972244 |
| trichospirura leptostoma gen. et sp. n. (nematoda: thelazioidea) from the pancreatic ducts of the white-eared marmoset callithrix jacchus. | | 1967 | 5624881 |
| births following the transfer of cultured embryos obtained by in vitro and in vivo fertilization in the marmoset monkey (callithrix jacchus). | the aim of this study was to determine whether marmoset monkeys are a suitable primate model for in vitro fertilization (ivf), embryo culture, and transplantation studies. a prostaglandin analogue given in early pregnancy and human chorionic gonadotropin given near the end of the ensuing follicular phase were used for controlling the reproductive cycle, timing oocyte collection, and synchronizing the cycles of oocyte donors and embryo recipients. five embryos obtained by ivf were transferred at ... | 1988 | 3137105 |
| infectious mononucleosis-like response in common marmosets infected with epstein-barr virus. | callithrix jacchus marmosets infected with epstein-barr virus (ebv) with or without concurrent treatment with cyclosporin a (cysa) remained healthy. five marmosets given virus alone developed lymphocytosis and heterophile antibody. antibody to ebv capsid antigens (vca) appeared and remained at titers of 1:40-1:80 from 15 weeks onward. two animals produced antibody to the r component of early antigens (ea) from six weeks onward. five cysa-treated ebv-infected marmosets showed no increase in total ... | 1984 | 6094675 |
| the enantiomers of the teratogenic thalidomide analogue em 12: 1. chiral inversion and plasma pharmacokinetics in the marmoset monkey. | the plasma pharmacokinetics of the enantiomers of 2-(2,6-dioxopiperidine-3-yl)-phthalimidine (em 12) and the racemic mixture of this substance were investigated in callithrix jacchus, a thalidomide-sensitive primate. single doses of 5 mg/kg body wt were administered orally or intraperitoneally. maximum plasma concentrations were reached 1 h after administration of the enantiomers, and 3 h after application of the racemate. the mean plasma elimination half-life was in the range of 5 h for the ena ... | 1988 | 3143339 |
| transplacental and direct exposure of mouse and marmoset to ethylnitrosourea: analysis of chromosome aberrations. | the effect of ethylnitrosourea (enu) on chromosomes of mouse bone marrow cells and transplacentally exposed embryonic liver cells was investigated. chromosome aberrations were found to be dose- and time-dependent. the maximum damage was seen 6 h after the exposure. chromosome aberrations were also induced in bone marrow cells and lymphocytes of marmosets (callithrix jacchus) directly exposed to enu. aberrations did not, however, occur in offspring whose mothers were treated with enu before conce ... | 1983 | 6137079 |
| effects of hypothalamic lesions upon the sexual and social behaviour of the male common marmoset (callithrix jacchus). | the sexual and associated behaviour of 10 adult male marmosets was recorded during pair tests with ovariectomized females, before and after bilateral thermal lesions of the hypothalamus. four sham-lesioned males served as controls. lesions varied in volume from 1.49 to 3.28 mm3 and extended from the ventromedial hypothalamus to the diagonal band of broca. precopulatory behaviours (anticipatory erections, tongue flicking and anogenital investigations of the female) as well as frequencies of mount ... | 1988 | 3143470 |
| embryotoxic effects of thalidomide-derivatives in the non-human primate callithrix jacchus. i. effects of 3-(1,3-dihydro-1-oxo-2h-isoindol-2-yl)-2,6-dioxopiperidine (em12) on skeletal development. | the response of pregnant marmosets (callithrix jacchus) to the thalidomide derivative em 12 was evaluated. em 12 was selected for these studies because it is more active than thalidomide and is much more stable for hydrolysis. skeletal gross structural abnormalities were observed when em 12 was given to marmosets for 3-7 days during the period between days 49 and 60 post ovulation. using the treatment schedule finally adapted in our laboratory, i.e. treatment during days 51-57 post ovulation, do ... | 1988 | 3355362 |
| the postnatal development of the temporomandibular joint of the common marmoset (callithrix jacchus). | the temporomandibular joints (tmj) of 55 male and 50 female common marmosets (callithrix jacchus) with an age range of 1 day- to < 12-yr-old have been studied to extend the knowledge on the craniomandibular articulation of this primate. details of changes in the bone structure, gross and functional anatomy, and histologic appearance of the marmoset tmj during the neonatal period, infancy, childhood, adolescence, and adulthood are compared with those which occur in the tmj of man. it is concluded ... | 1982 | 6153018 |