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monoclonal antibodies against mouse gamma-interferon inhibit tumoricidal macrophage activation by t lymphocytes.a monoclonal antibody, an-18.17.24, specific for murine interferon-gamma (ifn-gamma) was produced by immunizing wistar rats with ifn-gamma secreted by a t-cell lymphoma, l12-r4, upon stimulation with phorbol myristic acetate (pma). antiviral activity as well as tumoricidal activation induced by pma-stimulated l12-r4 cell supernatant or by con a-stimulated normal spleen cells were neutralized at the same extent by an-18 monoclonal antibody. moreover, depletion experiments showed that inhibition o ...19853930308
radiosensitization of human fibroblasts by 3-aminobenzamide: an inhibitor of poly(adp-ribosylation).the poly(adp-ribose) synthetase inhibitor 3-aminobenzamide (3ab) increases the radiosensitivity of normal human fibroblasts in tissue culture in a dose-dependent manner at noncytotoxic concentrations. 3ab was also found to inhibit the repair of potentially lethal damage as well as the recovery occurring when radiation was delivered as fractionated vs single exposures. however, repair as measured by an increased survival when radiation is delivered at low dose rate compared to high dose rate was ...19853936114
radiosensitization of human fibroblasts by 3-aminobenzamide: an inhibitor of poly(adp-ribosylation).the poly(adp-ribose) synthetase inhibitor 3-aminobenzamide (3ab) increases the radiosensitivity of normal human fibroblasts in tissue culture in a dose-dependent manner at noncytotoxic concentrations. 3ab was also found to inhibit the repair of potentially lethal damage as well as the recovery occurring when radiation was delivered as fractionated vs single exposures. however, repair as measured by an increased survival when radiation is delivered at low dose rate compared to high dose rate was ...19853936114
on steroid noradrenergic system interaction during the hypothalamic differentiation period in the female rat.neonatal administration of alpha-methyl-p-tyrosine, alpha-mpt, (1 mg s.c. on days 4 and 5) or 6-hydroxydopamine, 6-ohda, (100 or 600 micrograms s.c. on day 1) did not produce any change of the reproductive function in female rats. both drugs were unable to prevent the anovulatory syndrome induced by the administration on day 4 of testosterone propionate, tp, (25 micrograms) or estradiol benzoate, eb, (10 micrograms), but blocked the precocious vaginal opening induced by eb neonatal administratio ...19853937738
[a case of resected renal cell carcinoma with massive pancreatic metastases].a case of resected renal cell carcinoma with massive pancreatic metastases is reported. a 72-year-old man was diagnosed as suffering from obstructive jaundice. massive pancreatic tumor and left renal tumor were shown by several kinds of radiological examination. total pancreatectomy and left nephrectomy were performed. postoperatively this case was histologically diagnosed as renal cell carcinoma with massive pancreatic metastases. very few cases of resected renal cell carcinoma with pancreatic ...19853981807
aetiology and outcome of severe community-acquired pneumonia.between january 1972 and december 1981, 50 patients with severe community-acquired pneumonia were admitted to the intensive care unit of a district general hospital. a causal pathogen was identified in 41 cases (82%). streptococcus pneumoniae (16 cases), legionella pneumophila (15 cases) and staphylococcus aureus (5 cases) were the commonest. assisted ventilation was required in 44 patients, of whom 25 died (57%). all 5 patients with staphylococcal pneumonia and 12(75%) with pneumococcal pneumon ...19854031512
changes in the fetal heart rate of thoroughbred horse through the gestation. 19854046265
induction of goitre by ptu or kcio4 in male and female rats. effect of gonadectomy. 19734128226
[effect of epiphysectomy on the ovary of the golden hamster (mesocricetus auratus waterh.)]. 19674231631
[antistreptolysin o in mothers milk]. 19684237445
adp-induced binding of phosphofructokinase to the brain mitochondrial membrane. 19744276999
effects of neonatal thymectomy on polyoma tumor formation. 19654285798
potentiation of catecholamines by a new diphenylalkanolamine. ii. potentiation in various isolated organs. 19654291631
potentiation of catecholamines by a new diphenylalkanolamine. ii. potentiation in various isolated organs. 19654291631
double-stranded rnas (poly i:c) in the prevention of viral infections. 19704316618
double-stranded rnas (poly i:c) in the prevention of viral infections. 19704316618
behavioral aspects of melanocyte-stimulating hormone (msh). 19734363916
avian tumor virus proteins and rna in uninfected chicken embryo cells.the content of proteins p19 and p15 (mol wt 19,000 and 15,000, respectively) of avian leukovirus in various types of uninfected chicken embryos has been determined by radioimmunoassay. all chicken embryos examined, including embryos which have thus far been classified as group specific (gs) antigen negative by complement fixation tests, contained these viral proteins as well as p27 as previously reported. the embryos known as "gs antigen-positive" type contained about five times as much of these ...19744372405
serosal transfer of glucose during peristalsis. 19694388096
inability of dextran to release kinin in rats. 19704392253
hydroxytryptamine turnover decreased by the antidepressant drug chlorimipramine. 19704392254
experimental allergic neuritis in the dog and its comparison with the naturally occurring disease; coonhound paralysis. 19744451040
[current knowledge in the endocrinology of reproduction of domestic animals. 7. endocrinology of labor and lactation]. 19744605597
the action of some anticonvulsant drugs on cobalt-induced epilepsy and on the bemegride threshold in alert cats. 19724626570
separation of glomerular basement membrane substances by sodium dodecylsulfate disc gel electrophoresis and gel filtration. 19724640761
the intermolecular space of reconstituted collagen fibrils. 19734686200
the intermolecular space of reconstituted collagen fibrils. 19734686200
[comparative studies on cerebral vessel pathology in animals and man]. 19734725275
[na+, k+ and ca2+ content in the glandular stomach tissue of chickens normally and in a vitaminosis]. 19734791115
clonal analysis of vertebrate myogenesis. ii. environmental influences upon human muscle differentiation. 19744826280
the dynamic structure of a flat small intestinal mucosa studied on the explanted rat jejunum.small pieces of jejunum with an intact blood supply were explanted to the anterior abdominal wall in rats. six weeks after explantation the mucosa appeared totally flat in many areas, both histologically and under the dissecting microscope. the structure of the flattened mucosa was shown to be identical to that in coeliac disease with hypertrophied intervillous ridges. a dynamic study with tritium-labelled thymidine demonstrated a considerably increased turnover in the flat mucosa with some diso ...19744834554
[study on the genetic characteristics of various mucous strains of e. coli k 12]. 19674876506
role of polynucleotide ligase in t4 dna replication. 19684877007
[gastric secretion of hcl, pepsin and intrinsic factor in man after stimulation with synthetic human gastrin]. 19684889597
[diagnostic possibilities in a larva migrans visceralis infection, results on animal experiments]. 19684976088
inhibition of pancreatic lipase by tetracyclines. 19704985815
measurement of human meiotic chromosomes according to arm lengths and centromere position. 19725054224
ultrastructure of the process of secretion in the rat uterine epithelium at preimplantation. 19725055813
the relationship between antibody formation and deoxyribonucleic acid (dna) synthesis in mouse spleen during primary and secondary response to sheep erythrocytes (src). 19725069736
[gamma glutamyl carboxypeptidase from chicken pancreas]. 19725073874
[primary transport of acute patients. optimal use of rescue resources exemplified by the canton of graubünden]. 20113927607
[chemical historiography in the 19th and 20th century]. 20144271246
inducibility of metallothionein biosynthesis in cultured normal and menkes kinky hair disease fibroblasts: effects of copper and cadmium.metallothionein biosynthesis is not induced by extracellular copper in menkes kinky hair disease (mkhd) or in normal cultured fibroblasts under the conditions of these experiments. in the presence of copper, mkhd fibroblasts also incorporated less cysteine than did normal fibroblasts. extracellular cadmium greatly enhanced the uptake of cysteine in both normal and mkhd cultures. by the technique of polyacrylamide gel electrophoresis, it was demonstrated that metallothionein is induced by cadmium ...2004471576
information technology: implementing a nurse information system.this article explains the remit of a specially designated project nurse in preparing for the implementation of a nurse information system. the main components of a system--rostering/staff planning, workload/dependency levels and care planning--are defined and the project nurse's role in educating ward-based staff is described. the key to successful management of the necessary changes, the author argues, is adopting a 'bottom-up' approach to implementation in which nurses are encouraged to develo ...20061622800
carbohydrate specificity of the receptor sites of mistletoe toxic lectin-i.the carbohydrate specificity of mistletoe toxic lectin-i (ml-i) was studied by haemagglutination-inhibition assay. the results indicated that ml-i has a broad range of affinity for gal alpha,beta linked sequences. the galabiose (e, gal alpha 1----4gal) sequence, a receptor of the uropathogenic e. coli ligand, was one of the best disaccharide inhibitors tested. the lectin also exhibits affinity for lac(gal beta 1----4glc), t(gal beta 1----3galnac), i/ii(gal beta 1----3/4glcnac) and b(gal alpha 1- ...20061525184
"raynaud's disease" in migraineurs: one entity or two?two cases are reported of patients who were diagnosed as having both migraine and raynaud's disease. because they were able to achieve effective control of both headaches and extremity temperature after undergoing a comprehensive approach--utilizing medication, biofeedback, and psychotherapy--it is suggested that both conditions are manifestations of the same disorder. it is recommended that a first step in approaching concurrent diagnoses of this type involve combined treatment as is often used ...20061446993
seventh international meeting of the society for advancement of contraception. singapore, 4-11 november 1990. 20071950709
regulation of alcohol consumption by the renin-angiotensin system: a review of recent findings and a possible mechanism of action.the renin-angiotensin system has traditionally been associated with the regulation of fluid and electrolyte balance. in this review we summarize the data which ascribes a completely new function to this system, i.e., the regulation of alcohol consumption. in addition, we suggest a possible mechanism for this effect based on the concept of a satiety or stop process. the approach taken was to examine the effect on alcohol intake of a wide variety of drug, genetic, dietary, surgical and neurosurgic ...20071852316
[clinical study of osteoporosis]. 20082614196
[single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ...20092786584
[therapeutic aspects of infantile asthma. part i]. 20102876486
effect of target contrast and luminance on soft contact lens and spectacle visual performance.the visual performance of four soft contact lenses was investigated using visual acuity charts at six contrast levels (from 90 to 8%) under normal (250cd/m2) and reduced 92.5cd/m2) luminances. this investigation reveals significant differences not detected by conventional visual acuity measurements; in general, reducing luminance or contrast increases the magnitude of any recorded difference. furthermore, the study pointed to a significantly poorer visual performance with spectacles compared to ...20123416617
initiating a community pharmacy residency. 20133728303
neurological examination in subjects over 65 years: an epidemiological survey.the frequency of abnormal findings at neurological examination was analyzed in an unselected sample of elderly people aged 67-87 years. absent deep tendon reflexes and impairment of proprioceptive sensation rarely occurred in the elderly. limitation of upward gaze and convergence appear a common finding, especially in the very old. overall, the presence of cortical disinhibition signs (primitive reflexes and paratonia) did not discriminate well between subjects without cns disease and demented p ...20082330069
transcardiac passage of thrombus--ultrasonographic visualization.a patient is described in whom a right atrial thrombus was seen, by two-dimensional echocardiography, in the act of embolizing into the pulmonary circulation.20092702500
[long-term follow-up of vena cava filters: real-time sonography and the native x-ray image].in 16 patients with vena cava filters (12 günther filters, 4 kimray-greenfield filters) a follow-up study was performed by ultrasound and abdominal plain film. ultrasound allows to identify type and location of the filter as well as the entrapment of emboli. abdominal radiography is useful for exact evaluation of changes in filter position. combination of sonography and plain films is considered to be most suitable for follow-up studies of caval filters.20093035643
[long-term follow-up of vena cava filters: real-time sonography and the native x-ray image].in 16 patients with vena cava filters (12 günther filters, 4 kimray-greenfield filters) a follow-up study was performed by ultrasound and abdominal plain film. ultrasound allows to identify type and location of the filter as well as the entrapment of emboli. abdominal radiography is useful for exact evaluation of changes in filter position. combination of sonography and plain films is considered to be most suitable for follow-up studies of caval filters.20093035643
psychopathic adaptations in the vulnerable patient.the purpose of this paper is to discuss the fluidity of symptoms that a group of psychiatric patients presents during the passage of time. although clinically recognizable and worthy of attention, this fluctuation makes the illness difficult to conceptualize under a definitive diagnostic category. such a dilemma is very familiar to the hospital psychiatrist. the authors present a case to illustrate the fluidity of symptoms manifested by a patient throughout the course of her illness. awareness o ...20123359395
dollars and dedication: how high is an honorarium? 20154511183
glossary of terms for thermal physiology. 20164765838
[biochemical effects of continuous and discontinuous muscular work (interval work)]. 20164720306
myeloid and erythroid progenitor cells from normal bone marrow adhere to collagen type i.one of the mechanisms by which normal hematopoietic progenitor cells remain localized within the bone marrow microenvironment is likely to involve adhesion of these cells to extracellular matrix (ecm) proteins. for example, there is evidence that uncommitted, hla-dr-negative progenitor cells and committed erythroid precursors (bfu-e) bind to fibronectin. however, fibronectin is not known to mediate binding of committed myeloid (granulocyte-macrophage) progenitors, raising the possibility that ot ...20041370640
[comparative study on drinking water in japan (akita) and hawaii]. 20051169517
halifax medical center. evolution of a family practice residency program. 20133625152
fractured odontoid with fractured superior articular process of the axis. report of three cases.we report three patients in whom a fractured odontoid process was associated with a fracture of the superior articular process of the second cervical vertebra. although there were no signs of neurological disorder, damage to the c1-c2 joint in all three patients made fusion necessary. forced lateral flexion is suggested as the possible mechanism of injury.20143957998
[immunological in vitro tests in the assessment of specific cellular reactivity in tuberculosis]. 20051079782
[the vascular skin graft in the surgery of urethral stenosis]. 20154603909
[agranulocytosis in memory of edgar reye (30 may 1882-11 december 1945)]. 20154579460
[industrial medicine. occupational cancer]. 20164902038
[rotation of an eccentric dipole in a conducting sphere: an analytical model for the vcg (proceedings)]. 200092229
[temporary restoration material--scutan]. 2000110534
electroconvulsive therapy: an overview.modifications in technique, including the use of anesthesia and muscle-relaxing drugs, make electroconvulsive therapy safe and easy to administer. there are few contraindications, complications are rare, and efficacy is well-documented.2004441398
[symptom of para-esophageal shadow of the tumor in x-ray diagnosis and evaluation of the effectiveness of radiotherapy of esophageal cancer]. 20051196036
xeromammography at a community hospital. a year's experience. 20051183210
thickenings in the coronary arteries in infancy as an indication of genetic factors in coronary heart disease.in finland, mortality from coronary heart disease is high, and much higher in the eastern than in the western countries. both left and right coronary arteries of 141 children who died under one year of age at the children's hospital, university of helsinki, were investigated. thirty-two of these children formed a western and 41 an eastern group according to the birthplaces of their grandparents in finland. correlations were tested between this geographical distribution and some dimensions of the ...20051112002
review of breast cancer screening guidelines. 20061544090
[immunohistochemical classification and ultrastructural study of hyperparathyroidism].immunohistochemical and ultrastructural studies were performed on cases with hyperparathyroidism. the relationship between histology and cell activity in hyperfunctioning parathyroid glands was studied. furthermore, the synthesis-secretion process of parathyroid hormone (pth), which has been more or less elucidated biochemically, was studies by a morphological means. the subjects employed in the present study were 23 cases of primary hyperparathyroidism (phpt) and 31 cases of secondary hyperpara ...20061479749
a protocol system to satisfy research specific, disease specific, physician specific, and patient specific informational needs.the department of medicine at loyola university medical center chicago (lumc) has developed and is utilizing a patient information protocol system (pips) to address clinical and research informational needs. pips, an integrated module of the department's patient information management system (pims), enables end-users to access pre-defined informational templates or "protocols". protocols detail pre-defined data requirements for patient management or clinical research needs. each protocol consist ...20061482966
effect of postdischarge surveillance on rates of infectious complications after cesarean section.decreases in length of stay for surgical procedures and increased outpatient surgery affect accuracy of surgical wound infection rates. to assess accuracy of rates for infectious complications after delivery by cesarean section, we implemented postdischarge surveillance at our hospital (4800 annual deliveries). physician questionnaires were used. response rate was greater than 90%. during the 5 months before postdischarge surveillance the overall infection rate was 1.6%; afterward the rate incre ...20061326238
pulmonary agenesis as part of the vacterl sequence.pulmonary agenesis is an uncommon anomaly that has been reported in isolation and in association with other congenital defects. such defects include oesophageal atresia, cardiac malformation, horseshoe kidney, and anal atresia. over a period of three years we have seen five neonates or fetuses with unilateral agenesis of the lung. all the cases had three or more anomalies seen in the vacterl sequence in addition to the pulmonary atresia. none had a tracheo-oesophageal fistula. none were the prod ...20073415317
lymph node staging in patients with clinically negative neck examinations by ultrasound and ultrasound-guided aspiration cytology.to assess the usefulness of ultrasound and ultrasound-guided fine-needle aspiration cytology in detecting occult cervical lymph node metastases, 107 patients with squamous cell carcinoma of the head and neck, who underwent 132 elective neck dissections, had preoperative ultrasound examination. during the assessment of the last 54 patients, who underwent 70 elective neck dissections, ultrasound-guided aspiration cytology was available. although ultrasound was able to detect lymph node metastases ...20071951890
an ultrastructural study of in vivo interactions between lymphocytes and endothelial cells in the pathogenesis of the vascular leak syndrome induced by interleukin-2.lymphokine-activated killer (lak) cells play a major role in the induction of the vascular leak syndrome (vls). to understand the mechanism of this syndrome, the authors examined light and electron microscopic alterations in the lung, liver, spleen, kidney, and heart of mice in which vls was produced by the administration of interleukin-2 (il-2) (seven injections of 600,000 iu each for a period of 4 days). the results of these studies disclosed that considerable damage had been done to the endot ...20071913455
relation between all cause standardised mortality ratios and two indices of deprivation at regional and district level in england.the use of mortality data in the form of standardised mortality ratios (smrs) to measure the need for health care resources in the resource allocation working party (rawp) formula in england has been criticised for underestimating the wider effects of adverse socioeconomic conditions on need, particularly in inner city areas. to assess this criticism, we explored the relationships at nhs regional and district levels in england between two indicators of illness from the 1981 census, two contrasti ...20082592910
[current status of national indemnity and bilateral hilar adenopathy in siberian silicosis]. 20082277423
assessment of thyroid function: complications after treatment with fenoprofen. 20093087516
precision excision of pulmonary metastases--a useful technique. 20102926757
clinical, morphopathological and toxicological studies in acute benzodiazepine poisonings. 20102908774
lymphadenopathy of kimura's disease.kimura's disease is an important category of reactive lymphadenopathy in the oriental population. the enlarged nodes are mostly located in the head and neck region. salient pathological changes include florid germinal centers, warthin-finkeldey type polykaryocytes, vascularization of germinal centers, increased postcapillary venules in the paracortex, eosinophilic infiltration, and sclerosis. the pathology of kimura's disease is quite different from that of angiolymphoid hyperplasia with eosinop ...20102919716
the pituitary gland of the musk shrew. suncus murinus l. (insectivora), with special reference to the cytology of the adenohypophysis. 20114114309
the pituitary gland of the musk shrew. suncus murinus l. (insectivora), with special reference to the cytology of the adenohypophysis. 20114114309
some biological and social factors of risk associated with the birth of pre-term infants.the main purpose of the present study was to evaluate the effects of factors associated with spontaneous pre-term births so that the high risk woman could be identified before or at early stages of pregnancy. for this purpose, we have compared the measurements of 21 anthropometric traits and mean fluctuating asymmetry over 8 bilateral anthropometric traits, as well as age, occupation, education, previous obstetric history, complications during pregnancy, medicines received during and after pregn ...20113169522
lupus anticoagulant and lacunar infarctions.lupus anticoagulant is more often associated with thromboembolism than hemorrhage. we have observed two cases of lupus anticoagulant associated with basal ganglion lacunar infarction, causing contralateral choreoathetosis. one patient had no evidence of lupus or other etiology, and responded to antiplatelet therapy, while the other was found to have systemic lupus erythematosus with nephritis and was successfully treated with steroids. the effects of lupus anticoagulant on platelet prostacyclin ...20113133215
oesophageal pain exacerbated by propranolol. 20113113570
biographical sketches--69. robert spencer dyer lyons 1826-1886: a centenary tribute. 20123539863
inspiratory muscles during exercise: a problem of supply and demand.the capacity of inspiratory muscles to generate esophageal pressure at several lung volumes from functional residual capacity (frc) to total lung capacity (tlc) and several flow rates from zero to maximal flow was measured in five normal subjects. static capacity was 126 +/- 14.6 cmh2o at frc, remained unchanged between 30 and 55% tlc, and decreased to 40 +/- 6.8 cmh2o at tlc. dynamic capacity declined by a further 5.0 +/- 0.35% from the static pressure at any given lung volume for every liter p ...20123403432
diagnosis. 20133826101
unilateral renal oncocytoma: a case report.a case of unilateral renal oncocytoma is reported. diagnosis, clinical features and management of the tumour are discussed in the light of international literature. the value of angionephrography in the diagnosis of the tumour and in the preoperative planning of surgical therapy is emphasized.20133818213
tailoring genes for crop improvement. an agricultural perspective. 20133593177
[healing and prevention as a problem of medical science to-day]. 20144249199
effects of intensity on the phototactic responses of adult anuran amphibians: a comparative survey. 20144206432
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