| [requirement of cyclic 3',5'-monophosphate in the production of a permeability increasing factor by vibrio cholerae]. | | 1986 | 3018312 |
| renal functional changes after converting enzyme inhibition or nitroprusside in hypertensive rats. | | 1987 | 3038467 |
| passive protection of calves against experimental infection with salmonella typhimurium. | cows were vaccinated with formalin-killed salmonella typhimurium approximately seven weeks and two weeks before parturition to investigate whether passive immunity could protect their calves against experimental s typhimurium infection. after birth the calves were left with their dam for 48 hours and then separated and fed cold, stored colostrum from their own dam for a further eight days. oral challenge five days after birth with 10(8) s typhimurium did not result in the death of these calves e ... | 1988 | 3061151 |
| passive protection of calves against experimental infection with salmonella typhimurium. | cows were vaccinated with formalin-killed salmonella typhimurium approximately seven weeks and two weeks before parturition to investigate whether passive immunity could protect their calves against experimental s typhimurium infection. after birth the calves were left with their dam for 48 hours and then separated and fed cold, stored colostrum from their own dam for a further eight days. oral challenge five days after birth with 10(8) s typhimurium did not result in the death of these calves e ... | 1988 | 3061151 |
| comparative densities of wuchereria bancrofti microfilaria in paired samples of capillary and venous blood. | concurrent finger-prick and venous blood samples were obtained from 43 patients infected with wuchereria bancrofti. microfilariae were counted in blood smears and on nuclepore filters. based on the numbers of microfilariae in 20-microliters finger-prick samples, an expected (theoretical) number of microfilariae in venous samples was calculated. this expected value was compared to the actual number of microfilariae present in venous blood. the actual number of microfilariae present ranged from 0. ... | 1988 | 3067320 |
| acrosomal proteinase activity of human spermatozoa and relation of results to semen quality. | an assay for measuring the acrosomal proteinase activity of human spermatozoa with the use of a microscope slide coated with a thin layer of gelatin as a protein substrate was developed and applied to study the semen of 82 males from infertile couples and 15 normal donors. acrosomal protease activity is indicated by a clear area of proteolyzed gelatin (halo) about the sperm head. probit analysis revealed two populations divided at a halo diameter of 14 microns. the patient samples were grouped a ... | 1988 | 3068243 |
| [osmotic resistance of erythrocytes in cattle]. | | 1986 | 3087113 |
| cellular distribution of lysosomal hydrolase activities in the regenerating rat liver. | cathepsins b and d, beta-galactosidase, and acid phosphatase activities were found to be decreased in the regenerating rat liver, the reduction being maximal around the peak of hepatocyte mitoses (30 h). to investigate whether these changes could be heterogeneously distributed among hepatic cells, total cell populations from control or two-thirds hepatectomized rat livers were dissociated by the collagenase perfusion technique and analysed by different procedures. isopycnic centrifugation in a m ... | 1986 | 3089641 |
| effects of total parenteral nutrition on the development of intestinal endotoxemia in rats: a comparison between glucose and lipid. | the effects of parenteral nutrition (pn) and of the difference in the pn regimens between glucose and lipid emulsion on the development of endogenous endotoxemia were studied in 40 wister rats. endotoxemia was induced by occluding the superior mesenteric vein (smv) for 30 min. the plasma endotoxin in the portal blood at the time of the release of the smv occlusion and that in the arterial blood 10 min after the release were quantified. twenty of the 40 rats had received pn for 48 hr prior to the ... | 1986 | 3091866 |
| chronic cardiac toxicity after inhalation of 1,1,1-trichloroethane. | two patients showed evidence of chronic cardiac toxicity after repeated exposure to 1,1,1-trichloroethane. in both cases there was circumstantial evidence of a deterioration after routine anaesthetic use of the related compound halothane. an adolescent boy who sniffed trichloroethane presented with multiple ventricular arrhythmias during tonsillectomy. follow up showed mild chronic left ventricular impairment. a 54 year old man had repeated industrial exposure to trichloroethane and deteriorated ... | 1987 | 3105712 |
| chronic cardiac toxicity after inhalation of 1,1,1-trichloroethane. | two patients showed evidence of chronic cardiac toxicity after repeated exposure to 1,1,1-trichloroethane. in both cases there was circumstantial evidence of a deterioration after routine anaesthetic use of the related compound halothane. an adolescent boy who sniffed trichloroethane presented with multiple ventricular arrhythmias during tonsillectomy. follow up showed mild chronic left ventricular impairment. a 54 year old man had repeated industrial exposure to trichloroethane and deteriorated ... | 1987 | 3105712 |
| localization of the binding sites of porcine tissue-type plasminogen activator and plasminogen to heparin. | to localize the binding region of porcine tissue-type plasminogen activator (ec 3.4.21.31) (t-plasminogen activator) to heparin, functionally active a and b chains (molecular mass of each 33 kda) were separated from the two-chain t-plasminogen activator after mild reduction and alkylation. the a chain bound to fibrin-sepharose, but not to heparin-sepharose. in contrast, the b chain showed amidase activity toward hd-ile-pro-arg-p-nitroanilide (s-2288) and a high affinity for heparin-sepharose, bu ... | 1987 | 3120775 |
| [the effect of intraperitoneal administration of isoprenaline on atpase activity in the brain of rats of different ages]. | | 1985 | 3155871 |
| [psychological evaluation of diabetic students and their families]. | a population of 29 diabetic school children has been studied with the purpose of evaluating the repercussion the disease has on the psychosocial development of the child. eysenck's inventory of personality, achembach's ipcds and the drawing of the human figure have been employed as psychological test. the sociological aspects are valued through interviewing and questionnaires. the outstanding conclusions are: 1. diabetes does not condition the development of a specific personality. 2. psychiatri ... | 1988 | 3190018 |
| coordinative interactions in the separation of insulin and its derivatives by high-performance liquid chromatography. | the effects of various inorganic cations and anions on the chromatographic behaviour of insulin and its derivatives have been investigated. it was shown that on an octadecylsilica column at a given eluent composition the retention of insulins depends primarily on the nature of the anions. the cations have a secondary effect, depending on their size and coordination ability. the mechanism of the effect of the ions is complex. it includes the formation of ion pairs, their influence on dissociation ... | 1987 | 3323216 |
| use of lytic bacteriophage for actinomyces viscosus t14v as a probe for cell surface components mediating intergeneric coaggregation. | a lytic bacteriophage for actinomyces viscosus t14v (the reference strain for actinomyces coaggregation group a) was isolated from raw sewage. this phage, designated bf307, also lysed the t14v-derived nonfimbriated mutant pk455-2 as well as a. viscosus mg-1 and t14av but not the other serotype 2 or serotype 1 strains of this species that were tested or any of nine actinomyces naeslundii isolates. phages bf307 belonged to bradley morphological group c and was similar in appearance to the a. visco ... | 1988 | 3335409 |
| an experimental study on ethanol elimination at subphysiological temperatures. | hepatocytes isolated from fed and fasted rats have been used to study the rate of ethanol elimination at different incubation temperatures. in the presence of exogenous pyruvate, hepatocytes from fed and 42 hr fasted rats, eliminated ethanol at 37 degrees by a rate of 11.6 +/- 3.4 and 6.4 +/- 0.8 nmol/min./mg of cell protein (+/- s.d.; n = 5), respectively, which are comparable to the rates obtained in vivo. the ethanol oxidation rate in cells from rats of both nutritional states correlated line ... | 1988 | 3353352 |
| an experimental study on ethanol elimination at subphysiological temperatures. | hepatocytes isolated from fed and fasted rats have been used to study the rate of ethanol elimination at different incubation temperatures. in the presence of exogenous pyruvate, hepatocytes from fed and 42 hr fasted rats, eliminated ethanol at 37 degrees by a rate of 11.6 +/- 3.4 and 6.4 +/- 0.8 nmol/min./mg of cell protein (+/- s.d.; n = 5), respectively, which are comparable to the rates obtained in vivo. the ethanol oxidation rate in cells from rats of both nutritional states correlated line ... | 1988 | 3353352 |
| tachycardia during the onset of one-kidney, one-clip renal hypertension: role of the renin-angiotensin system and av3v tissue. | we have previously demonstrated a transitory tachycardia during the early phase of one kidney, one clip (1k1c) hypertension in the rat, when the basal heart rate (hr) is measured daily under resting conditions. in the present study, in control rats, marked tachycardia (406 +/- 11 vs 320 +/- 4 bpm during the control period) was observed on the first day of electrolytic lesion of the anteroventral third ventricle (av3v) region. the basal hr declined progressively thereafter and was normal 14 days ... | 1988 | 3370491 |
| high metabolic activity in the visual cortex of early blind human subjects. | glucose metabolism has been studied in the visual cortex of early blind human subjects. in the forebrain of these subjects, regional glucose utilization was the highest in the striate and prestriate cortical areas. furthermore, this activity was higher than in blindfolded sighted subjects, whether at rest or during an auditory or tactile task. these observations raise the question of the functionality of the blind's visual cortex. | 1988 | 3370494 |
| [establishment of the maximum permissible concentration of polydimethyldiallylammonium chloride in reservoir water]. | | 1988 | 3396898 |
| 7b2, a new protein secreted by human functionless pituitary tumours, in vitro. | a novel pituitary protein, 7b2, of approximately 180 amino acids has been suggested to colocalise with lh in the pituitary gonadotropes. increased secretion of lh is known to occur in functionless pituitary tumours. we have therefore measured 7b2 immunoreactive equivalents in the 24-h medium of explant pituitary cultures prepared from 17 functionless, 20 somatotropic, 16 prl secreting and 8 corticotropic adenomas. a synthetic fragment corresponding to amino acids 23-39 of 7b2 was used to raise a ... | 1988 | 3400405 |
| convergent afferent inputs to neurones in nucleus paragigantocellularis lateralis in the cat. | neuronal activity was recorded in nucleus paragigantocellularis lateralis (pgl) of the cat in response to stimulation of the dorsal periaqueductal grey matter (dpag), parabrachial nucleus (pbn) nucleus raphe magnus (nrm), and nucleus tractus solitarii (nts). stimulation in dpag or pbn evoked excitatory responses whilst the prevalent response to stimulation in nrm or nts was inhibition of neuronal activity. 45/55 (82%) of cells tested received convergent inputs from 2 or more sites of stimulation ... | 1988 | 3409033 |
| [screening and other alternatives in the fight against hiv]. | | 1987 | 3424318 |
| mammalian alcohol dehydrogenase: characteristics of class iii isoenzymes. | the kinetic characteristics of alcohol dehydrogenase class iii have been studied using class iii isoenzymes purified from human liver (x-adh) and rat liver (adh-2). our results confirm that long chain primary alcohols and aldehydes are the best substrates, although some aromatic compounds can also be actively metabolized. kinetic analysis suggests an ordered bibi mechanism for x-adh. ethanol can be oxidized by class iii isoenzymes at high substrate concentration, but with a very slow rate. thus, ... | 1987 | 3426675 |
| [analysis of the chemosensitivity test by human tumor clonogenic assay and subrenal capsule assay]. | the antitumor activities of several chemotherapeutic agents were tested in the human tumor clonogenic assay (htca) and in subrenal capsule assay (srca). the results obtained in these two assays and clinical response were compared. 1. colony growth was observed in 43 of 73 tumors (58.9%), and the adequate colony growth to evaluate the response of therapeutic groups was obtained in 21 tumors (28.8%). 2. control growth adequate to meet evaluable assay criteria was obtained in 38 of 43 tumors (88.4% ... | 1987 | 3431536 |
| [lysosomal cationic proteins of granulocytes in the blood of healthy and sick monkeys]. | | 1987 | 3433992 |
| relationships between pulmonary inflammation, plasma transudation, and oxygen metabolite secretion by alveolar macrophages. | we have previously shown that alveolar macrophages from normal rabbit lungs do not synthesize reactive oxygen intermediates unless first conditioned by culture in vitro in the presence of serum for 24 to 48 hr. this conditioning process is mediated by a serum constituent that partitions on gel exclusion columns with an apparent m.w. of 30,000 to 50,000 daltons. alveolar macrophage conditioning in vitro requires protein synthesis, is associated with the generation of membrane nadph oxidase activi ... | 1986 | 3486910 |
| a common mechanism of chromosomal translocation in t- and b-cell neoplasia. | the chromosomal breakpoint involved in the t(8;14)(q24;q11) chromosome translocation in the skw-3 cell line, which directly involves the 3' flanking region of the c-myc gene, was cloned and sequenced. the breakpoint on chromosome 8 mapped to a position 3 kb 3' of c-myc while the chromosome 14 breakpoint occurred 36 kb 5' of the gene for the constant region of the alpha chain of the t-cell receptor (tcr). the translocation resulted in a precise rearrangement of sequences on chromosome 8 and what ... | 1986 | 3490692 |
| [cigarette smoking and lung metabolism--effects of cigarette smoking on plasma levels of complement c3a and c5a in rabbits]. | | 1987 | 3500346 |
| physiology and pathophysiology of the colonic circulation. | there is growing evidence that colonic blood flow is controlled by both intrinsic and extrinsic factors. the existence of intrinsic vascular control mechanisms is evidenced by pressure-flow (and oxygen uptake) autoregulation, reactive hyperemia, vascular responses to acute venous hypertension, and a functional hyperemia. although myogenic factors have long been considered to be solely responsible for the intrinsic ability of the colon to regulate its blood flow, recent developments indicate that ... | 1986 | 3536216 |
| insulin stimulates cord blood erythroid progenitor growth: evidence for an aetiological role in neonatal polycythaemia. | polycythaemia in the neonate is a serious pathologic entity which occurs particularly in infants of diabetic mothers (idm) and small-for-gestational age (sga) infants. both of these conditions are associated with fetal hyperinsulinaemia. cultures of cord blood mononuclear cells from polycythaemic idm showed increased growth of late erythroid progenitor colonies, compared to cord blood mononuclear cells from non-polycythaemic infants, reflecting a possible expansion of this progenitor population ... | 1986 | 3539174 |
| interferon in renal cell carcinoma. the ucla experience. | three sequential studies of alpha interferon were performed in a total of 84 evaluable patients with metastatic renal cell carcinoma. in study i, conducted from 1981 to 1982, 43 patients received human leukocyte alpha interferon (ifn alpha) 3 x 10(6) u/day, 5 days per week for 12 weeks. in study ii, performed in 1983, vinblastine (0.1 mg/kg/week) was added to the same ifn alpha regimen in 22 subjects. study iii, held from 1984 to 1985, evaluated the effects of escalating doses of interferon alfa ... | 1987 | 3542184 |
| fine structure of the organic matrix of human pancreatic stones. | pancreatic stones that were removed from the pancreatic ducts of patients with chronic calcifying pancreatitis were decalcified so the organic matrix could be studied by scanning and transmission electron microscopy. the observations made by scanning electron microscopy were compared with those made on undecalcified stones, and the findings were correlated with light microscopic observations. after the calcium carbonate was removed, the stones consisted of multiple partitions arranged like a spo ... | 1986 | 3575306 |
| ethanol-induced inhibition of testosterone biosynthesis in vitro: lack of acetaldehyde effect. | acute ethanol intake has been shown to decrease plasma testosterone levels in rodents and man. this is mainly due to inhibition of testosterone synthesis, but there is still some controversy about the mechanisms responsible for the inhibition. these mechanisms were studied in the present experiments with isolated rat leydig cells. leydig cells were incubated for two hours in sealed plastic vials with various concentrations of ethanol (0.3-40 mm) or acetaldehyde (5-40 microm). very low ethanol co ... | 1987 | 3593480 |
| cardiovascular response to sudden strenuous exercise. | cardiac responses to sudden strenuous exercise were studied in seven dogs instrumented to measure cardiac output (q), stroke volume (sv), left ventricular (lv) pressure, aortic pressure and circumflex coronary blood flow (cbf). the dogs were run on a treadmill at 12.9 km/h, 20% grade for 15s without prior warm-up. during the first 10s of the run, hr and q increased rapidly. by 2s, myocardial o2 requirements, as estimated from either the tension time index (tti) or calculated wall tension, had in ... | 1987 | 3632566 |
| promoting informed consent of women in labor. | laboring women are increasingly being asked to participate in perinatal research. these women should be considered captive or special subjects who deserve greater protection of their rights. essential elements of informed consent are reviewed. specific guidelines are suggested for promoting informed consent for women in labor participating in clinical research. | 1986 | 3639933 |
| effect of prostaglandin e1 on deposition of autologous labelled platelets onto human atherosclerotic lesions in vivo. | the effects of infusions of prostaglandin e1 (pge1) on platelet deposition at atherosclerotic sites in vivo in man have been examined. thirteen patients with atherosclerotic vascular disease received intravenous pge1 25 mg/kg/min for 6 hours daily for 5 days. prostaglandin e1 had no effect on platelet uptake at atherosclerotic sites but prolonged platelet half-life significantly (p less than 0.001). | 1987 | 3684830 |
| [experimental hypovitaminosis d in guinea pigs administered different amounts of vitamin c]. | the experimental model of d-hypovitaminosis is first obtained on guinea pigs. it is established that the least degree of its manifestation is determined under conditions of the optimal supply of the organism with vitamin c. the necessity of using ascorbic acid in a complex of rachitis prophylaxis measures is substantiated. | 1986 | 3705209 |
| effect of sodium pentobarbital on behavioral thermoregulation in rats and mice. | in this study on behavioral thermoregulation, male sprague-dawley rats were given intraperitoneal (ip) injections of sodium pentobarbital in doses of 0, 1, 5, 10 or 15 mg/kg and male cba/j mice were given doses of 0, 5, 10, 15 or 30 mg/kg. the animals were immediately placed in a temperature gradient which allowed them to select their preferred ambient temperature (ta). the preferred ta of rats increased following an injection of 10 mg/kg sodium pentobarbital, whereas, the barbiturate had no eff ... | 1986 | 3754969 |
| [detection of the thyrostatic drug methylthiouracil (mtu) using high performance liquid chromatography (hplc) and high performance thin layer chromatography in tissues and tissue extracts of fattening cattle]. | | 1986 | 3775348 |
| influence of single neonatal treatment with allylestrenol or diethylstilbestrol on microsomal enzyme activity of rat liver in adulthood. | a single neonatal treatment of rats with a steroid (allylestrenol or diethylstilbestrol) did not alter the later activity of the hepatic microsomal (cytochrome p-450) enzyme system, but inhibited the inducer action of another steroid (testosterone) administered at the age of six weeks. this suggests that a hormonal imprinting-like mechanism also operates in the case of enzymes. | 1986 | 3784633 |
| influence of single neonatal treatment with allylestrenol or diethylstilbestrol on microsomal enzyme activity of rat liver in adulthood. | a single neonatal treatment of rats with a steroid (allylestrenol or diethylstilbestrol) did not alter the later activity of the hepatic microsomal (cytochrome p-450) enzyme system, but inhibited the inducer action of another steroid (testosterone) administered at the age of six weeks. this suggests that a hormonal imprinting-like mechanism also operates in the case of enzymes. | 1986 | 3784633 |
| hydatid disease: research and control in turkana. ii. the role of immunological techniques for the diagnosis of hydatid disease. | immunological studies have been applied to the immunodiagnosis of human hydatidosis in turkana and for the specific identification of echinococcus eggs, particularly in regard to their potential for the assessment of a hydatid control programme in the north-west of the district. a high rate of false negatives has been obtained with sensitive antibody tests for proven hydatid patients in turkana and presents problems for prevalence estimation in the population. a seroepidemiological study using s ... | 1986 | 3787677 |
| unusual association of bone marrow necrosis, disseminated intravascular coagulation, and a rare 8;16 chromosomal translocation in an adult patient with acute nonlymphocytic leukemia. | in a patient with acute nonlymphocytic leukemia of the classic type (fab subtype m2), three infrequently observed phenomena occurred together; bone marrow necrosis, disseminated intravascular coagulation, and an 8;16 chromosomal translocation. all three resolved with antileukemic therapy, only to reemerge when the leukemia relapsed, suggesting a causal relationship among these phenomena. such observations and the consistent application of cytogenetic studies to patients with leukemia may help el ... | 1987 | 3791177 |
| immunoelectrophoresis in quality control of veterinary clostridial products. | each year the pharmaceutical industry produces 150-250 batches of anti-clostridial vaccines and sera for veterinary use in the u.k. under medicines act requirements these products must be tested for potency before release to the public, such tests being performed in animals. the ministry of agriculture, as licensing authority, also carries out potency test on representative samples of these products. to avoid unnecessary use of animals we employ immunoelectrophoresis (iep) as a screening test. r ... | 1986 | 3792642 |
| [the effect of neythumun in comparison with 2-cyanoethylurea on the white blood count of the rat]. | the stimulation effect of neythymun-sol f+k (nthy) and 2-cyanethylcarbamide (cec) on the leucocytopoesis was studied in 30 wistar rats and a moderate but significant increase in the total number of leucocytes was found. the increase produced by cec didn't prove significantly higher than that by nthy. after 32 d the blood count showed a substantial difference concerning the neutrophils with an increase from 3000 to 9000 without deviation to the left, which was found only under neythymun. this com ... | 1986 | 3797457 |
| immunization with heat-killed pneumococci, but not pneumococcal capsular polysaccharides, improves survival in splenectomized mice. | immunization with pneumococcal capsular polysaccharides (pn ps) is advocated after splenectomy to decrease the risk of overwhelming sepsis. the clinical and experimental evidence for the benefit of immunization after splenectomy is controversial. various reports in the literature have claimed a benefit of immunization after splenectomy, but careful review of methodologies reveals that heat-killed pneumococci (pn) were used to immunize the experimental animals. since we have not been able to prot ... | 1987 | 3807350 |
| influence of mouse genotype on responses of central biogenic amines to alcohol intoxication and aging. | dopamine and serotonin responses to various periods of alcohol treatment have been followed in striatum and hippocampus of two inbred strains of mice and related to the effect of aging. a striking strain dependency was noted for chronic alcohol effects and also for senescence. for both neurotransmitters studied the c57bl strain loses tolerance to prolonged alcohol injury earlier than the balb/c strain. this loss of tolerance accompanying aging may be indicative of more widespread changes in cns ... | 1986 | 3814344 |
| identification of two cases of bovine undifferentiated tumours (squamous cell carcinoma and adenocarcinoma) by electron microscopy. | two cases of undifferentiated tumours were found in cows. electron microscopy revealed that one was an undifferentiated squamous cell carcinoma of unknown primary site and the other an undifferentiated adenocarcinoma of the lung. | 1985 | 3837797 |
| diversity and structure of genes of the alpha family of mouse t-cell antigen receptor. | we have analysed 19 complementary dna clones encoding the alpha-chain of the t-cell antigen receptor derived from thymic transcripts, and find that 15 of them contain partial or complete variable (v alpha) genes. seven of these genes cross-hybridize to over 40 germline v alpha gene segments in southern blot analyses. of the 19 joining (j alpha) sequences examined, 18 seem to be encoded by distinct gene segments, hence the repertoire of j alpha gene segments is much larger than those of the immun ... | 1985 | 3839904 |
| protein antigens of encapsulated klebsiella pneumoniae surface exposed after growth in the presence of subinhibitory concentrations of cephalosporins. | it recently has been reported by us that cephalosporins, at a concentration below that influencing growth rate, reduced the production of enterochelin and capsule formation of iron-depleted klebsiella pneumoniae. we now report on the antigenicity of the outer membrane components and surface-exposed protein antigens of iron-depleted cells grown in the presence or absence of cephalosporins. all major outer membrane proteins, including iron-regulated membrane proteins, were immunogenic. encapsulate ... | 1985 | 3914857 |
| stoichiometry and kinetics of the interaction of prostaglandin h synthase with anti-inflammatory agents. | we have examined the kinetics, stoichiometry, and chemical nature of the interaction of three anti-inflammatory agents (indomethacin, flurbiprofen, and meclofenamic acid) with pure ovine prostaglandin h synthase. the kinetics of the interaction with the synthase for each of the three agents, monitored by the decrease in cyclooxygenase activity, was consistent with the model proposed by rome and lands (rome, l.h., and lands, w.e.m. (1975) proc. natl. acad. sci. u.s.a. 72, 4863-4865): a rapid and ... | 1985 | 3930499 |
| enhanced responsiveness of the coronary blood vessel of the dog heart-lung preparation to pgi2 after chronic chemical sympathectomy. | chronic chemical denervation of the sympathetic nervous system with 6-oh dopamine resulted in an augmentation of the coronary blood flow (cbf) increase inherent in the canine heart-lung preparation, but not in an augmented accumulation of 6-keto pgf1 alpha in the circulating blood. in denervated hlp, 6-keto pgf1 alpha was lower and the vasodilator response to pgi2 larger at the start of the experiments. it was concluded that exaggerated increase in cbf was due to a potentiation of the vasodilato ... | 1985 | 3932732 |
| hypercalcemia in the neuroleptic malignant syndrome. | the neuroleptic malignant syndrome (nms) developed in a 32-year-old man following fluphenazine enanthate administration. hypercalcemia was initially present, perhaps reflecting release of calcium from skeletal muscle stores. the elevated serum calcium levels support the existence of a peripheral muscle abnormality in the pathogenesis of the nms and provides another point of similarity between nms and malignant hyperthermia. | 1985 | 3970627 |
| injections of atropine into the caudate nucleus impair the acquisition and the maintenance of passive avoidance. | two experiments were performed to test the hypotheses that cholinergic activity of the caudate nucleus (cn) is involved in the acquisition and in the maintenance of passive avoidance behavior. rats were trained, in one trial, to avoid one of two compartments of a conditioning box and retention of the task was measured 24 hours later. several doses of atropine were injected into the cn of independent groups of animals. in experiment 1 the atropine was injected 2 minutes after training and in expe ... | 1985 | 3983217 |
| copper deficiency in infants fed cow milk. | | 1985 | 3998919 |
| excretion of radioactivity in faeces and urine of rats injected with 3h,14c-lipopolysaccharide. | the route of excretion of lipopolysaccharide (lps) and its possible degradation in vivo was studied in rats using biosynthetically radiolabelled lps from salmonella abortus equi, carrying 3h activity exclusively in fatty acids and 14c activity in fatty acids and sugars. following intravenous injection of the above lps in as2 rats with or without anaesthesia, excretion of radioactivity occurred mainly in the faeces and to smaller extent in urine. the rate of excretion was slow, a large part of th ... | 1985 | 4005148 |
| trends in cancer mortality in italy, 1955-1978. | trends in age-specific and age-standardized cancer death certification rates in italy from 1955 to 1978 were analyzed. in males total cancer mortality rates increased in all age groups. however, when respiratory and other tobacco-related neoplasms were excluded, death certification rates were roughly stable up to age 64. moderate decreases in overall cancer mortality have been apparent at younger ages (35-44) since the early 1970's. in females, all the age-specific and the age standardized, unde ... | 1985 | 4024279 |
| preferential uptake of intravenously administered hyaluronidase (hyalosidase) by damaged rat myocardium. | the induction of myocardial infarction in rats by ligation of the left-anterior coronary artery was confirmed by measurement of increased plasma levels of creatine kinase, aspartate aminotransferase and lactate dehydrogenase. using this model system it has been established that intravenous administration of 125i-labelled hyaluronidase to rats resulted in a preferential uptake of the enzyme by damaged myocardium as compared to normal heart tissue. | 1985 | 4027352 |
| immunization and immunosuppression in mice reared for high or low immune responsiveness against nematospiroides dubius. | | 1985 | 4030203 |
| dyschondroplasia/osteochondrosis of the femoral trochanter in the fowl. | of 104 lame broilers, 12 birds with femoral trochanteric abnormalities were identified by post-mortem and radiographic examination. defects occurred in ossification of either the trochanteric zenith or its medial aspect. lesions were identified as dyschondroplasia, osteochondrosis or osteochondrosis dissecans affecting the articular surface of the femoral trochanter. in the absence of concomitant musculoskeletal disease, degrees of lameness can be attributed to trochanteric lesions. breaches in ... | 1985 | 4031131 |
| [sequential histochemical studies of the esophageal carcinoma in rats induced by n-methyl-n-amylnitrosamine]. | | 1985 | 4032830 |
| tabulation and assessment of 113 human surveillance cytogenetic studies conducted between 1965 and 1984. | there is an increasing tendency to monitor human exposure to genotoxic chemicals by the assessment of chromosomal aberrations or sister-chromatid exchanges (sces) in peripheral blood lymphocytes. in order to assess the sensitivity of these techniques, and to discern minimal criteria for their conduct, a survey of 113 human lymphocyte cytogenetic surveillance studies conducted between 1965 and 1984 has been undertaken. the present survey indicates the urgent need for standardization of study prot ... | 1985 | 4033683 |
| selective regulation of carboxypeptidase peptide hormone-processing enzyme during enkephalin biosynthesis in cultured bovine adrenomedullary chromaffin cells. | bovine adrenomedullary chromaffin cells in culture were incubated with reserpine or forskolin, two agents acting through different mechanisms, which increase cellular [met]enkephalin levels by 2-fold after 72 h. cells were harvested and chromaffin granules were purified on a linear sucrose gradient. after reserpine treatment, carboxypeptidase-processing enzyme specific activity in chromaffin granule fractions was stimulated 1.9-fold, and co2+-stimulated carboxypeptidase specific activity was sti ... | 1985 | 4039723 |
| extravasation of polymorphonuclear leukocytes from the cerebral microvasculature. inflammatory response induced by alpha-bungarotoxin. | postcapillary venules represent the segment of the microvasculature most vulnerable to inflammatory processes. while there is a considerable body of data on the peripheral vasculature, little is known about the primary events occurring during inflammatory reactions in cerebral blood vessels. we introduce here a model by which the migration of polymorphonuclear leukocytes through the cns endothelial barrier can be studied. alpha-bungarotoxin is used as a chemotactic agent and is shown, for the fi ... | 1985 | 4053172 |
| [proportions of the femur and humerus in relation to bone length]. | taking as a starting point the known fact that the vertical proportions of man are dependent upon stature, a study has been made to investigate if the relations between individual segments of long tubular bones are also dependent upon overall bone length. for these investigations, use was made of 356 human femurs of unknown sex, which were obtained from the bone collection of the institute of anatomy (kurp 1979), and 70 human humeri of known sex (kropf 1979), which were obtained from the institu ... | 1985 | 4073525 |
| immunohistochemistry of liver in alpha1-antitrypsin deficiency. a comparative study. | | 1974 | 4137719 |
| [functional changes of the thyroid and adrenal glands in the course of immunological reactions]. | | 1973 | 4144094 |
| proceedings: correlation of androgenic activities of the lower testosterone esters in rat, with rm values and hydrolysis rates. | | 1973 | 4150536 |
| gamma-aminobutyric acid: drug-induced elevation in monkey brain. | | 1974 | 4153580 |
| the isolation of erythrocyte membrane proteins in aqueous media. | | 1972 | 4199550 |
| rate of thrombin-fibrinogen reaction in some mammalian species. | | 1974 | 4213348 |
| the development of a rest chair profile for healthy and notalgic people. | | 1969 | 4241558 |
| effect of phenobarbital on bile flow and bile salt excretion in the rat. | | 1971 | 4253069 |
| enzymatic methylations. ii. in vitro inhibition of trna and protein methylation by nicotinamide and isonicotinic acid hydrazide: activation of a s-adenosylmethionine-splitting enzyme in rat liver. | | 1972 | 4261254 |
| interaction of genes controlling ultraviolet sensitivity in neurospora crassa. | two independently segregating ultraviolet (uv) sensitivity genes in neurospora crassa interact synergistically resulting in uv sensitivity approximately twice that expected based on an evaluation of the sensitivities of the individual mutants. the mutant genes singly and together reduce photoreactivation (pr) in vivo although a pr enzyme is produced which exhibits normal activity in vitro. | 1972 | 4263406 |
| [studies on the dermotoxins of the 6 clostridium welchii types in rabbits]. | | 1965 | 4287430 |
| effect of hypophysectomy and adrenalectomy on enzymes concerned with nicotinamide adenine dinucleotide synthesis. | | 1967 | 4292487 |
| combination chemotherapy in accelerated phase of chronic granulocytic leukemia. | | 1969 | 4303268 |
| [cytotoxicity of silica dust and mixed dust for guinea pig alveolar macrophages in vitro. attempt at quantitative estimation]. | | 1969 | 4323257 |
| foam cells of rabbit atheromatous lesion. identification and cholesterol uptake in isolated cells. | | 1971 | 4331666 |
| [sequence of amebic hepatic lesions in the rabbit]. | | 1972 | 4349095 |
| problems in the detection of the oncogenic potential of viruses or cell cultures. | | 1972 | 4349823 |
| correlation of c-type virus (wf-1) production and heme synthesis in a rat fibroblastic cell line. | | 1974 | 4360116 |
| [abortive infections produced by myxoviruses and rhabdoviruses and their possible causes]. | | 1974 | 4374832 |
| a new pneumococcus type. type 12a. | | 1967 | 4383090 |
| importance of sperm capacitation for gamete contact in the rabbit. | | 1974 | 4413787 |
| importance of sperm capacitation for gamete contact in the rabbit. | | 1974 | 4413787 |
| ionic effects on the motility of bull and chimpanzee spermatozoa. | | 1974 | 4413987 |
| studies of phospholipid-requiring bacterial enzymes. 3. purification and properties of uridine diphosphate glucose:lipopolysaccharide glucosyltransferase i. | | 1972 | 4553445 |
| [effect of humoral antibodies on the rejection of renal transplants]. | | 1972 | 4572549 |
| letter: influenza virus vaccination and renal transplant rejection. | | 1974 | 4595178 |
| agglutination of african primate and rodent erythrocytes by adenoviruses, reoviruses, and enteroviruses. | african nonhuman primate and rodent erythrocytes were tested for agglutination by adenoviruses, reoviruses, and enteroviruses. squirrel erythrocytes were agglutinated by reovirus serotypes and adenovirus types 3, 11, 16, and 21. adenoviruses also agglutinated brazza monkey erythrocytes to the same titers as those obtained with either rhesus or grey monkey cells. prototype reovirus types 1 and 2 agglutinated grey monkey erythrocytes to much lower titers than either squirrel or human group o red c ... | 1972 | 4631106 |
| effect of weak acids on amino acid transport by penicillium chrysogenum: evidence for a proton or charge gradient as the driving force. | a variety of weak acids at and below their pk(a) are potent inhibitors of transport in penicillium chrysogenum. the effective compounds include sorbate, benzoate, and propionate (common antifungal agents), indoleacetate (a plant hormone), acetylsalicylate (aspirin), hexachlorophene, and a yellow pigment produced by the mycelia under nutrient-deficient conditions, as well as the classical uncouplers 2,4-dinitrophenol, p-nitrophenol, and azide. the results suggest that a proton gradient or charge ... | 1973 | 4632394 |
| human skeletal muscle phosphorylase activities with exercise and training. | | 1972 | 4640795 |
| [experimental studies for the fluorochroming of human spermatozoa with special reference to so-called vital fluorochroming]. | | 1972 | 4651092 |
| a computer for the calculation of skeletal muscle vascular resistance. | | 1972 | 4652900 |
| study of albumin synthesis in relation to urea synthesis. | | 1973 | 4746768 |
| [the teratogenic effect of busulfan on testis cells of the fetal rat]. | | 1973 | 4800446 |