| complement-induced histamine release from human basophils. iii. effect of pharmacologic agents. | human serum activated with zymosan generates a factor (c5a) that releases histamine from autologous basophils. previously we have presented evidence that this mechanism for c5a-induced release differs from ige-mediated reactions. the effect of several pharmacologic agents known to alter ige-mediated release was studied to determine whether they have a similar action on serum-induced release. deuterium oxide (d2o), which enhances allergic release, inhibited in a concentration-dependent fashion th ... | 1977 | 65434 |
| [methodical recommmendations for conduction of the hemagglutination test with erythrocytic cholera enterotoxic diagnostic agent (eceda)]. | | 1976 | 66381 |
| neutralization of salmonella toxin-induced elongation of chinese hamster ovary cells by cholera antitoxin. | a partially purified preparation of the delayed skin permeability factor from salmonella typhimurium caused chinese hamster ovary cells to elongate. the elongation effect and the skin test activity were blocked by monospecific rabbit antisera against cholera toxin and against the b fragment of cholera toxin, | 1977 | 67084 |
| [use of color differential medium and russell-i medium in the diagnosis of cholera vibrio]. | | 1977 | 67254 |
| specific inhibition of viral neuraminidases by an inhibitor, neuraminin, produced by streptomyces sp. | | 1977 | 67704 |
| experimental cancer immunotherapy: modification of tumor cells to increase immunogenicity. | firmly established transplantable c3h/hej mammary carcinomas can be inhibited by host challenge with vibrio cholerae neuraminidase (vcn)-treated tumor cells. the effect is totally immunospecific, even vcn-treated tumors bearing shared mammary tumor virus (mtv) antigen cannot induce the regression. thus, vcn is capable of increasing the immunogenicity of the private, unique-unshared tumor antigens on mammary carcinomas; vcn is incapable of increasing the immunogenicity of the shared mtv-associate ... | 1976 | 68699 |
| characterization of the thyrotropin receptor and its involvement in graves' disease. | | 1977 | 69601 |
| antigenic similarity of heat-labile enterotoxins from diverse strains of escherichia coli. | with use of the rabbit intestinal loop model, heat-labile enterotoxins from 21 escherichia coli strains isolated from a wide spectrum of patients with diarrheal diseases were all neutralized to high titer by two antisera prepared against enterotoxins of either e. coli or vibrio cholerae. these findings suggest marked immunological similarity among heat-labile enterotoxins from a heterogenous group of e. coli. | 1977 | 69630 |
| [possible errors in bacteriological diagnosis of cholera]. | | 1977 | 69759 |
| [dry media on yeast hydrolysates for growing vibrio cholerae]. | | 1977 | 72881 |
| antibiotic-induced colitis implication of a toxin neutralised by clostridium sordellii antitoxin. | a toxin(s) has been demonstrated in the stools of two patients with antibiotic-associated colitis. this toxin(s) was heat-labile, was rapidly lethal for hamsters, increased vascular permeability in rabbit skin, and was cytotoxic for cells in tissue-culture. it was neutralised by clostridium sordellii antitoxin but not by antitoxins prepared against other clostridia; escherichia coli, and vibrio cholerae toxins. these characteristics were identical to those of a toxin implicated in the aetiology ... | 1977 | 73011 |
| secretory iga against enterotoxins in breast-milk. | a pool of colostrum from guatemalan mothers (guatemalan colostrum)) obtained 2-4 days post partum inhibited the induced fluid accumulation in rabbit ileal loops when incubated with vibrio cholerae or escherichia coli enterotoxin. there was a linear relationship between the quantity of colostrum used and the protection achieved. pools of guatemalan breast-milk obtained 15-30 days post partum and north american breast-milk had the same effect when tested with e. coli and v. cholerae enterotoxins, ... | 1976 | 73692 |
| the thomsen agglutination phenomenon: a discovery revisited 50 years later. | | 1978 | 74917 |
| phage-induced changes in vibrio cholerae: serotype and biotype conversions. | phage infection of vibrio cholerae resulted in antigenic changes. a strain of biotype cholerae serotype ogawa was converted into serotype hikojima and gained the ability to synthesize antigenic factor c. some phage-converted strains remained stable after subculture and were immune to superinfection with the same phage. the stable converted strains were lysogenic and released phage having a host range similar to the phage of the donor strain. reinfection of unstable converted strains which had "l ... | 1978 | 75188 |
| [device for re-seeding in the tests for vibrioflora]. | | 1977 | 75321 |
| [use of the method of macrophage migration inhibition for titration of toxic activity in microbial fractions]. | | 1977 | 75324 |
| antigenic relationship between the common antigen (oep) of pseudomonas aeruginosa and vibrio cholerae. | antibodies were found by the oep-passive hemagglutination test to cross-react with the common antigen (oep) of pseudomonas aeruginosa in sera of rabbits immunized with two serotype (inaba and ogawa) strains of vibrio cholerae. the titer in the oep-passive hemagglutination reaction rose later than did the agglutinin titer and reached a peak of 640 to 1,280. the titers of oep antibody formation in rabbits immunized with v. cholerae were almost the same as that of p. aeruginosa. the common antigen ... | 1978 | 75846 |
| [use of dry nutrient media for identification of the vibrio]. | | 1978 | 75999 |
| a rapid assay for neuraminidase. the detection of two differences in activity associated with virus transformation. | neuraminidase (acylneuraminyl hydrolase, ec 3.2.1.18) activity in fibroblast homogenates was measured by a rapid and simple assay with a synthetic substrate. the activity of neuraminidase in virus transformed hamster fibroblasts was increased over the normal counterpart. in addition, the differential activity seen using the synthetic substrate and fetuin made it possible to detect an enzyme activity hitherto not described. the advantages of this assay for metabolic screening are discussed. | 1978 | 77684 |
| technical improvements in the mixed antiglobulin rosetting reaction with consequent demonstration of high numbers of immunoglobulin-bearing lymphocytes in viable preparations of human peripheral blood. | a modification of the mixed antiglobulin rosetting reaction (marr) to improve sensitivity as a test for immunoglobulin (ig)-bearing human blood lymphocytes is described. a mean 5.7%, lymphocytes ig-positive by the marr when rosettes were formed in medium containing 0.2% bovine serum albumin (bsa), increased to 20% when rosettes were formed in 5% bsa or by incubating the lymphocytes or indicator erythocytes with vibrio cholerae neuraminidase before rosetting. under these various rosetting conditi ... | 1978 | 78951 |
| lipopolysaccharides of vibrio cholerae (ii)--an immunochemical study on o-antigenic structure-- [proceedings]. | | 1978 | 79666 |
| interaction between vagal and chemoreceptors afferents in ventilatory response to transient hypercapnia (awake rabbits). | the ventilatory response to a transient hypercapnia was studied in four awake rabbits maintained in a volume displacement plethysmograph : the increase in inspiratory volume (vi) was associated or not with an increase in inspiratory and expiratory durations (ti and te). these ventilatory variations were consistent with the activation of the peripheral chemoreceptors by carbon dioxide (short latency of the initial response). after vagal blockade by local anaesthesia, relative ventilatory variatio ... | 1978 | 80170 |
| stimulation of cyclic amp secretion in vero cells by enterotoxins of escherichia coli and vibrio cholerae. | the morphological response of vero cells to escherichia coli heat-labile enterotoxin was similar to that of cholera toxin and was accompanied by increases in the intracellular level of cyclic amp. the effects of both enterotoxins were enhanced by the presence of phosphodiesterase inhibitor and inhibited by heat or specific antisera. accumulation of cyclic amp preceded the morphological response. | 1978 | 80381 |
| evidence of acquired immune deficiencies in mediterranean lymphoma. a possible aetiological link. | patients with mediterranean lymphoma (m.l.) had a significant reduction in humoral immunity (igg and igm) as well as impaired cellular immunity (50% were anergic to three antigens--p.p.d., mumps, and dinitrochlorobenzene). any hypothesis for the pathogenesis of m.l. has to account for the peculiar geographic distribution of the disease, the age and sex incidence, the plasma-cell nature of the tumours, the associated heavy plasmacytic proliferation with relatively intact intestinal mucosa, involv ... | 1978 | 80636 |
| cholera, non-vibrio cholera, and stomach acid. | fasting and postprandial stomach acid production were low in 16 of 37 bangalees convalescing from cholera or non-vibrio cholera. gastric juice of hypochlorhydric patients did not kill cholera vibrios in vitro, whereas that from normochlorhydric patients rapidly killed vibrios in concentrations up to 10(10)/ml. to determine whether hypoacidity resulted from cholera or was a common predisposing factor, basal and betazole-hydrochloride-stimulated acid production were measured before and after chole ... | 1978 | 81410 |
| cannabis, hypochlorhydria, and cholera. | in 90 volunteers participating in a vaccine-development programme consumption of beer more than 3 days a week was linked with high stomach acid output, and smoking of cannabis greater than 2 days a week was linked with low acid output. in 92 volunteers challenged with vibrio cholerae or enterotoxigenic escherichia coli, heavy use of cannabis was associated with more voluminous diarrhoea. cannabis use may be an important factor predisposing to severe diarrhoea. | 1978 | 81411 |
| pathophysiological effects of vibrio cholerae and enterotoxigenic escherichia coli and their exotoxins on eucaryotic cells. | | 1978 | 82199 |
| demonstration of shared and unique immunological determinants in enterotoxins from vibrio cholerae and escherichia coli. | immunodiffusion and biological neutralization studies demonstrated that the heat-labile enterotoxin (lt) from escherichia coli has antigenic determinants in common with each of the isolated subunits (a and b) of the enterotoxin (choleragen) from vibrio cholerae. each of the enterotoxins also possesses unique antigenic specificities. monospecific antiserum to lt was prepared by immunization with antigens derived by immune precipitation of e. coli cell-free supernatant with isolated specific antic ... | 1978 | 83301 |
| vibrio cholerae in kent. | | 1979 | 84280 |
| the displaced ganglion cell in the avian retina: developmental and comparative considerations. | | 1979 | 84539 |
| modes of transmission of cholera in a newly infected population on an atoll: implications for control measures. | to determine the modes of transmission in a cholera epidemic in a newly infected population on an atoll, two studies were conducted, in which persons with cholera were individually matched, by age and sex, with neighbourhood controls. among the first recognised cases, cholera was associated with frequent (daily or weekly) consumption of raw lagoon fish that had been salted and partially dried. vibrio cholerae was isolated from the lagoon, which was contaminated by human wastes. during the declin ... | 1979 | 84960 |
| rapid emergence of el tor vibrio cholerae resistant to antimicrobial agents during first six months of fourth cholera epidemic in tanzania. | 110 el tor vibrio cholerae isolates from 102 patients with cholera between november, 1977, and march, 1978, during the early stages of the fourth epidemic of cholera in tanzania had minimum inhibitory concentrations to tetracycline, chloramphenicol, nitrofurantoin, neomycin, ampicillin, and sulphadimidine determined. all isolates during the first month after the disease was recognised were fully sensitive to tetracycline, but 76% of isolates were resistant to the drug after five months of extens ... | 1979 | 85001 |
| leprosy's footprints in bone-marrow histiocytes. | | 1979 | 85259 |
| [resistence of head lice against gammexane (lindane) applies also to the nonalcoholic preparations]. | | 1979 | 85264 |
| [antigenic study of "serratia marcescens" isolated in france.ii.--characterization of o antigens and description of 5 new o factors, occurrence of serotypes and labelling of new h factors (author's transl)]. | the somatic o-antigens of 583 french isolates of serratia marcescens were studied with the aid of the tube o-agglutination technique sensitized by centrifugation. flagella antigens were identified by the h-immobilization test. five new o-antigens (o16 to o20) were found. an antigenic factor (co) common to isolates of serotypes o12:h9, o14:h12, o14:h20, and o13:h17 is described. agar cultures of serotypes o12:h9 and o14:h12 dissociated into two colonial types: iridescent colonies, and non-iridesc ... | 1978 | 85425 |
| in vitro synthesis of infectious transforming dna by the avian sarcoma virus reverse transcriptase. | infectious dna molecules, capable of transforming chicken embryo fibroblasts, can be synthesized by the rous sarcoma virus-associated reverse transcriptase in vitro. the optimal enzymatic conditions employed for infectious dna synthesis also facilitate maximum synthesis of genome length dna. analysis of the dna product synthesized by detergent-disrupted rous sarcoma virus under these conditions indicates that dna complementary to viral rna (minus-strand dna) is genome length in size, whereas dna ... | 1979 | 85719 |
| memory. | | 1979 | 85894 |
| immunochemical properties of oligosaccharide-protein conjugates with klebsiella-k2 specificity. i. specificity and crossreactivity of anti-conjugate versus anti-bacterial antibodies. | | 1979 | 86152 |
| dna polymerase with characteristics of reverse transcriptase purified from human milk. | a dna polymerase purified from a particulate fraction of human milk has biochemical and biophysical properties similar to those of viral reverse transcriptases. this enzyme is immunologically distinct from cellular dna polymerases obtained from a variety of human sources. | 1979 | 86209 |
| the structure of the o-antigenic side chain of the lipopolysaccharide of vibrio cholerae 569b (inaba). | mineral acid hydrolysis of the lipopolysaccharide from vibrio cholerae 569b (inaba) gives an oligosaccharide fraction which was shown, by use of 13c nmr and chemical methods, to be a regular alpha-(1 leads to 2) linked chain of d-perosamine (4-amino-4,6-dideoxy-d-mannose) units. this chain represents the o-antigen of the lipopolysaccharide, in which the amino functions are acylated with 3-hydroxypropionyl groups. the chromatographic properties of some hydroxamic acids are described and used to c ... | 1979 | 86366 |
| interplexiform cell of the mouse retina: a golgi demonstration. | a neuron of the inner nuclear layer (inl) with some processes extending to the outer plexiform layer (opl) and others to the inner plexiform layer (ipl) was discovered near the posterior pole of the mouse retina. the neuron's location and appearance are similar to the interplexiform cells of several other species. the relatively recent recognition of this cell type along with its characteristic of infrequent staining by the golgi technique make the extent of its distribution among species uncert ... | 1979 | 86528 |
| the puzzle of "urethral syndrome": a possible answer? | 82 strains of slow-growing, co2-dependent, gram-positive organisms have been isolated from the urine of 9 male and 73 female patients. 100% of the men and 93% of the women had urinary symptoms at the time of isolation, and 66% of the specimens showed pyuria. these organisms might account for the urinary symptoms of some patients previously diagnosed as having "urethral syndrome". preliminary data show that, if appropriate antibacterial treatment is given, most of these patients become symptom-fr ... | 1979 | 86778 |
| definition of two ld antigens in rhesus monkeys. | two rhesus (macaca mulatta) monkey lymphocyte-defined (ld) antigens have been identified using two typing cells as stiumlators in a one-way mixed leukocyte culture (mlc) assay. an analysis of the genetic behavior of these ld antigens in six rhesus monkey families revealed that both antigens were linked with rhla. one probable recombinant indicated that the ld locus lies outside the two known rhla-sd loci and the locus which controls the serum protein, properdin b(bf). these two antigens, ld1 and ... | 1979 | 87026 |
| long term growth in vitro of human t cell blasts with maintenance of specificity and function. | | 1979 | 87425 |
| cytotoxicity by cultured human lymphocytes: characteristics of effector cells and specificity of cytotoxicity. | | 1979 | 87435 |
| the separate roles of hapten and of carrier in the conformation of t cell-reactive determinants on aba-protein conjugates. | | 1979 | 87448 |
| regulation of ige antibody production by serum molecules. v. evidence that coincidental sensitization and imbalance in the normal damping mechanism results in "allergic breakthrough". | experiments presented in this paper were designed to test a new concept concerning the possible pathogenesis of the allergic phenotype. this concept, termed "allergic breakthrough" considers that one of the avenues toward the allergic phenotype involves coincidental sensitization combined with an imbalance in the normal damping mechanism that serves to limit ige antibody production. the three predictions of this concept that can be tested experimentally are: 1) manipulations that are effective i ... | 1979 | 87455 |
| ige antibody formation and aging. i. age-related changes in ige antibody formation and avidity for the dnp-determinant in mice. | | 1979 | 87474 |
| cytotoxic macrophages induced in hamsters by vaccinia virus: selective cytotoxicity for virus-infected targets by macrophages collected late after immunization. | | 1979 | 87476 |
| hour of onset of cholera and diarrhoea. | | 1979 | 87933 |
| the cerebellar projection from the lateral reticular nucleus as studied with retrograde transport of horseradish peroxidase. | the cerebellar projection from the lateral reticular nucleus (nrl) was studied in cats by means of retrograde axonal transport of horseradish peroxidase (the projection to the paramedian lobule was not included, see brodal, 1975, for afferents to this cortical region). the entire cerebellar cortex and all cerebellar nuclei receive fibres from the nrl. the strongest connection is with the anterior lobe and lobulus viiib of the posterior lobe vermis. as concerns the anterior lobe the observations ... | 1979 | 88191 |
| 4th international workshop on human gene mapping. report of the committee on the genetic constitution of the x and y chromosomes. | | 1978 | 88299 |
| lipopolysaccharide-derived serotype polysaccharides from neisseria meningitidis group b. | three immunologically distinct types of polysaccharides have been isolated by diethylaminoethyl (deae) chromatography from the lipopolysaccharide extracts of group b neisseria meningitidis. all types contain a set of common determinants, as well as distinct ones; all of these determinants are detectable by either immunodiffusion or enzyme-linked immunosorbent assay (elisa). the polysaccharides elute from a sepharose 4b column in the range of 2-3 x 10(5) daltons and have isoelectric points from 4 ... | 1979 | 88491 |
| specific binding of prolactin by the prostate gland of the rat and man. | specific binding sites for 125iodine-prolactin are present in membrane particles obtained from the rat ventral prostate, human benign prostatic hyperplasia and prostatic adenocarcinoma. in the ventral prostate glands of young rats (1 to 4 months old) specific binding of 125iodine-prolactin is higher than in older animals (greater than 8 months old). subcellular distribution studies revealed that specific 125iodine-prolactin binding activity is associated primarily with the 15,000 and 100,000 g p ... | 1979 | 88529 |
| techniques for evaluating humoral and cell-mediated immunity in mule deer fawns (odocoileus hemionus). | twenty mule deer fawns (odocoileus hemionus) were removed from their dams 48 h after birth, and hand-reared. methods for monitoring their immune capability are described. passive humoral immunity was determined by serum protein electrophoresis. active humoral immunity following clostridium toxoid vaccination was determined by immunodiffusion. cell-mediated immunity was assayed using contact sensitization to 1-nitro, 2,4-dichlorobenzene (dncb). | 1979 | 88530 |
| resistant vibrio cholerae el tor in tanzania. | | 1979 | 88577 |
| [immunotherapy of malignant growths (author's transl)]. | our knowledge of antigens which are associated with different types of malignant tumours is steadily increasing. these antigens exist in considerable numbers, but, so far with few exceptions, only their presence can be demonstrated by certain methods; to isolate and identify them has not yet been possible. these antigens are, therefore, suitable not so much for the primary diagnosis, but rather, like the carcinoembryonic antigen, the tissue-polypeptide antigen or the alpha-feto-protein, for asse ... | 1979 | 88728 |
| comparative studies of hageman factor (factor xii) in mammalian plasmas by immunological techniques. | | 1979 | 88740 |
| [the mucosa immune system and immunization by intestinal infections]. | | 1978 | 88841 |
| studies on histamine release induced by compound 48/80 and peptide 401 [proceedings]. | | 1979 | 88890 |
| differentiation between cyclic amp level and allergic histamine release in mast cells [proceedings]. | | 1979 | 88891 |
| a new assay of estrogen receptor by thin-layer gel filtration. | | 1979 | 88911 |
| alterations in distribution of sudanophilic lesions in rabbits after cessation of a cholesterol-rich diet. | | 1979 | 88945 |
| [heterogeneity in organization of lipids in the bacterial membrane]. | the lipids of micrococcus lysodeikticus membranes were 50%-substituted by phosphatidyl choline using lipid-exchanging proteins isolated from rat liver. the incorporation of phosphatidyl choline into the membrane did not significantly change the malate dehydrogenase activity and the temperature dependence activity in the arrhenius plots for the enzyme. gramicidin s--modifier of membrane lipids--had similar effects both on the intact membranes and on the phosphatidyl-enriched membranes. a conclusi ... | 1979 | 88966 |
| the value of alpha-fetoprotein and beta-human chorionic gonadotrophin in the management of testicular tumours. | serum alpha-fetoprotein and beta-human chorionic gonadotrophin levels were estimated in 115 patients. sixty-nine patients had non-seminomatous germ cell tumours and 34 patients had seminomas. twenty-six patients showed elevated serum makers. | 1978 | 88986 |
| the pathophysiology of asthma. | because postmortem studies of humans provide little information on the initial pathophysiologic events in asthma, animal models have been developed. recently the ascaris-allergic rhesus monkey has provided an opportunity to examine the onset of pathophysiologic changes following challenge and to correlate them with airway structure. these studies have suggested that the initial interaction between antigen and mast cells may occur in the bronchial lumen or in the epithelium superficial to the tig ... | 1979 | 89006 |
| trasylol prevents trypsin-induced shock in dogs. | the effect of simultaneous intravenous administration in the dog of bovine trypsin and trasylol followed by continued infusion of trasylol was studied. special attention was paid to the interchange between the dominating plasma protease inhibitors alpha1-antitrypsin and a-macroglobulins and to the disappearance of trasylol and its trypsin complexes from the circulation. the following results were obtained: 1) trypsin was preferentially bound by the alpha-macroglobulins, though trasylol is a stro ... | 1979 | 89067 |
| steroid secretion by in vitro perfused testes: inhibitors of testosterone biosynthesis. | | 1979 | 89816 |
| [application to the study of connections in the cns of the retrograde axonal transport of an iron-dextran complex]. | the retrograde axonal transport of an iron-dextran complex was observed in neurons of the substantia nigra and of the intralaminar nuclei of the thalamus, after previous injection into the striatum. the histochemical demonstration of iron is simple and rapid, and can be combined with that of horseradish peroxidase, under precise conditions in the sequence of reactions. the iron-dextran complex revealed to be a valuable material for neuronal connectivity studies in the central nervous system. | 1979 | 89914 |
| antigenic drift in type a influenza virus: sequence differences in the hemagglutinin of hong kong (h3n2) variants selected with monoclonal hybridoma antibodies. | | 1979 | 90425 |
| location of the antigenic determinants of bovine pancreatic ribonuclease. | four antigenic regions of native bovine pancreatic ribonuclease have been located by using antibodies that react specifically with segments 1--13, 31--79, and 80--124. these antibodies were purified by affinity chromatography on columns to which these peptide segments were bound. analysis of precipitin curves indicates that there are at least three antigenic determinants to which antibody molecules can bind simultaneously in the presence of excess antibodies. analysis of binding data, however, f ... | 1979 | 90520 |
| relative affinity of antisera for myelin basic protein (mbp) and degree of affinity heterogeneity. | | 1979 | 90641 |
| characterization of the antigenic determinants of cholera toxin subunits. | the antigenic specificity of purified preparations of a subunit, b subunit, alpha chain, and gamma chain of cholera toxin was studied by double immunodiffusion and radioimmunoassay with antisera produced in rabbits and mice. rabbits immunized with a subunit produced serum antibodies which were capable of binding radiolabeled a subunit, alpha chain, and b subunit. rabbits immunized with alpha chain produced serum antibodies that would bind radiolabeled alpha chain and a subunit. rabbits immunized ... | 1979 | 90654 |
| the genetics of an expanded secretor system. | the genetics of salivary secretion of abh blood group substance was investigated. eight secretor phenotypes were determined by sephadex g-100 chromatography. presence or absence of three different fractions were shown to be controlled by three different secretor gene loci. these loci are called sec1, sec2 and sec3. sec1 controls expression of the traditional secretor status. sec2 and sec3 are linked, but distinct, loci controlling the expression of low molecular weight abh substance in human sal ... | 1979 | 90711 |
| rubella vaccines. | | 1979 | 90773 |
| bottle feeding as a risk factor for cholera in infants. | to determine risk factors for cholera in infants, a retrospective matched-pair study of 42 cases and their controls was undertaken during an outbreak of el tor cholera in bahrain in the autumn of 1978. the highest attack-rate of cholera (125/10 000) occurred in infants in the 6--11 month age-group, which corresponds to the weaning age in this community. significantly more cases than controls were principally bottle fed (greater than 50% milk intake by bottle) than principally breast fed during t ... | 1979 | 90813 |
| antimicrobial susceptibility of vibrio cholerae from zaire and rwanda. | | 1979 | 90940 |
| viral liver disease. | | 1979 | 91032 |
| the structure and evolution of the hla--bw4 and bw6 antigens. | the hla--bw4 and bw6 antigenic determinants have been shown to co-migrate with hla--b determinants on gel-filtration, sucrose density gradient centrifugation and affinity chromatography, using lens culinaris lectin and antibody against human beta 2 microbulin. these and other published data imply that the hla--bw4 and bw6 determinants reside on the same polypeptide chain as other hla--b locus determinants. the implications of this in terms of the evolution of cross reacting groups of antigens at ... | 1979 | 91209 |
| [use of antistaphylococcal immune preparations in acute suppurative-septic staphylococcal diseases]. | | 1979 | 91270 |
| latex fetuin spheres as probes for influenza virus neuraminidase in productively and abortively infected cells. | fetuin bound latex spheres do not adhere to the membranes of non-infected cells but adhere to those of cells productively infected by fowl plague virus (fpv dobson strain). in contrast, asialo fetuin spheres do not attach to the membranes of productively infected cells. moreover latex fetuin spheres incubated with extracts of productively infected cells and extensively washed are specifically enriched in neuraminidase activity without any trace of haemagglutinin. these observations suggest that ... | 1979 | 91354 |
| ultrastructure of peripheral nerves of mice inoculated with rabies virus. | fourty adult female albino mice were inoculated in the right hind leg with rabies viruses of the street type. the mice were sacrificed with an interval of 24 hours each, starting in the next day after inoculation. from the 10th day ownwards the animals started presenting signs of paralysis, first on the leg where the viruses were inoculated anbnormalities were found in peripheral nerves compatible with axonal degeneration with secondary demyelination but the rabies viruses were not found in the ... | 1979 | 91359 |
| [anti-arrhythmic effect of tetrodotoxin in the late stage of experimental myocardial infarct]. | the action of tetrodotoxin (tt), blocking the fast sodium current, on arrhythmias that occurred 24 hours after occlusion of the coronary artery was studied in 10 dogs. tt injected intravenously in doses of 0.5--3.0 micrograms/kg significantly decreased the number of ventricular extrasystoles, and completely restored sinum rhythm in 4 animals. the maximum antiarrhythmic effect was noted 3 to 5 minutes after tt adminstration. it is suggested that arrhythmias and the antiarrhythmic effect of the dr ... | 1979 | 91393 |
| connectivity of the auditory forebrain nuclei in the guinea fowl (numida meleagris). | injection of tritiated leucine and proline into the nucleus ovoidalis of the guinea fowl (numida meleagris) produces terminal labeling in the palaeostriatum and in three adjacent zones (field l1-l3) of the auditory neostriatum (an). l2, situated between l1 and l3, receives the main input and corresponds to the former field l of rose. these neuroanatomically defined zones of the auditory neostriatum are also characterized by differing properties of their neurons. injection of radioactive material ... | 1979 | 91442 |
| short latency mechanically evoked somatosensory potentials in humans. | somatosensory potentials evoked by mechanical stimulation were recorded by surface electrodes over (1) the digital nerves in the index finger, (2) the median nerve at the wrist, (3) the median nerve near the axilla, (4) the brachial plexus, (5) the cervical cord at cii, (6) the scalp overlying the somatosensory cortex. nerve conduction velocities varied inversely with age and ranged from 43 to 68 m/sec. mechanically evoked potentials recorded from the electrodes overlying the digital nerves were ... | 1979 | 91479 |
| procaine-induced seizures in epileptic monkeys with bilateral hippocampal foci. | intravenous procaine hcl given at low doses (0.5-2.5 mg/kg) to two monkeys with bilateral alumina hippocampal foci depressed interictal spiking or had little effect. at 5.0 mg/kg unilateral limbic activation occurred. at 10.0 mg/kg unilateral or bilateral limbic activation and generalized seizures could be evoked within 3-10 min. at higher doses (15 and 20 mg/kg) bilateral limbic activation or brief (one min) generalized seizures occurred. the unilateral-onset psychomotor seizures were not ident ... | 1979 | 91502 |
| antigenic correlation between rat brain synaptic vesicles and rat bone marrow b lymphocytes. | rabbit anti-rat brain synaptic vesicle serum reacted with thymocytes and b lymphocytes in cytotoxicity and immunofluorescence assays. quantitative absorption analysis revealed that this antiserum contained antibodies specific for antigenic determinants on the surface membrane of a subpopulation of rat bone marrow b lymphocytes. | 1979 | 91533 |
| generation of a fibroblast chemotactic factor in serum by activation of complement. | when serum complement is activated by either the classical or alternative pathways, a factor with an apparent 80,000 mol wt is generated that is chemotactic for human dermal fibroblasts. the origin of this serum-derived chemotactic factor (sdcf) is not known; however, it may be a cleavage product from c5 because it is inactivated by monospecific antiserum to human c5, and it is not generated when the complement system is activated in human serum deficient in c5. sdcf is not chemotactic for human ... | 1979 | 91624 |
| human lung tumor-associated antigens of 32,000 daltons molecular weight. | lung tumor-associated antigens of approximately 32,000 daltons were recognized by the use of sensitive radioimmunoassays and rabbit antisera, one raised against an extract of pooled human malignant lung tissues and another raised against a cell line derived from a human squamous cell carcinoma of the lung. these antigens differ from antigens described previously, including carcinoembryonic antigen and alpha-fetoprotein. the antigens were detected on 13 of 13 lung tumors (of all histologic types) ... | 1979 | 91695 |
| [microscopic, immunochemical and ultrastructral study of livers histologically normal or subnormal in patients with hepatitis b surface antigen (hbs). report of 18 cases (author's transl)]. | liver specimens obtained by biopsy in 18 patients with asymptomatic hbs ag were studied with specific immunofluorescent technic for this antigen by light and electron microscopy. only insignificant changes were disclosed by routine microscopy examination. under light microscopy "ground glass" hepatocytes were found in eight cases. specific immunofluorescence was found positive in nine cases and was closely correlated with the "ground glass" hepatocytes in eight of them. in one on the three cases ... | 1979 | 92003 |
| concanavalin a stimulates phospholipid methylation and phosphatidylserine decarboxylation in rat mast cells. | when histamine release from rat peritoneal mast cells is stimulated by concanavalin a, membrane phospholipids are methylated in the early stage of this process. exogenously added phosphatidylserine enhances the concanavalin a-induced histamine release, and at the same time the lectin markedly stimulates the decarboxylation and methylation of phosphatidylserine. within minutes after the addition of concanavalin a to rat mast cells, the newly methylated phospholipids begin to disappear and an incr ... | 1979 | 92021 |
| micromplement fixation studies of human plasma prothrombin and purified prothrombin preparations. | | 1979 | 92071 |
| [cutaneous leishmaniasis. alcoy: an endemic zone]. | | 1979 | 92178 |
| horizontal organization of velocity characteristics in area 18 of the cat [proceedings]. | | 1979 | 92238 |
| effect of fat structure on total, on chylomicron, and on high-density lipoprotein cholesterol in the absorptive state in man [proceedings]. | | 1979 | 92248 |
| triiodothyronine (t3) receptors in brain and liver during induced hypothyroidism in rats [proceedings]. | | 1979 | 92254 |
| fate of a "maturation-specific" messenger rna during early germination of mung-bean seeds [proceedings]. | | 1979 | 92270 |
| [experimental use of prostaglandin f2 alpha to synchronize estrus in cattle]. | experiments were conducted for the use of prostaglandin to synchronise oestrus in dairy cows. one single dose of 5 mg f2-alpha prostaglandin was administered via the intrauterine route. the reference values of the control groups were matched by first insemination following induced oestrus among the best of the test animals which were inseminated twice. these values reached 72 and 96 hours following application accounted for 46.7 and 50.0 per cent. the yellow body phase, a prerequisite for oestru ... | 1979 | 92295 |
| immunological cross-reactivity between acid extracts of myelin, liver and neoplastic tissues: studies in immunized guinea-pigs. | groups of 4 guinea-pigs were immunized with acid extracts prepared from bovine myelin (ef), normal human liver tissue and malignant or benign neoplastic tissues in freund's complete adjuvant (fca1. the animals were weighed daily and examined for clinical signs of experimental allergic encephalomyelitis (eae). all the animals immunized with ef developed clinical symptoms of eae within 21 days of the initial immunization, whilst some of the animals immunized with certain tumour extracts developed ... | 1979 | 92328 |
| suramin: a potent inhibitor of the reverse transcriptase of rna tumor viruses. | suramin--a well-known antitrypanosomal agent--was found to exert a strong inhibitory effect on the rna-directed dna polymerase (reverse transcriptase) activity of several oncornaviruses such as moloney murine leukemia virus, murine rauscher leukemia viruses, moloney murine sarcoma virus and avian myeloblastosis virus. inhibition of enzyme activity was obtained with both endogenous viral rna and (a)n . oligo(dt) as the template-primer. suramin effected a 50% inhibition of the reverse transcriptas ... | 1979 | 92362 |