| intracavitary aminocaproic acid for massive pulmonary hemorrhage. | | 1984 | 6373174 |
| igg antibodies to purified aspergillus fumigatus antigens determined by enzyme-linked immunosorbent assay. | igg antibodies to three purified aspergillus fumigatus antigens were determined by enzyme-linked immunosorbent assay (elisa) in sera from 26 patients with definite pulmonary aspergillosis (group 1), 23 patients with suspected pulmonary aspergillosis (group 2), 8 patients with precipitating antibodies to a. fumigatus of undetermined clinical significance (group 3), and 113 healthy blood donors (group 4). with a 470,000-dalton antigen fraction elisa values exceeded the upper range of group 4 (0.72 ... | 1984 | 6373622 |
| [lung tumor and recurrent hemoptysis following tuberculosis]. | | 1984 | 6373657 |
| measurement of specific ige and igg antibodies against aspergillus fumigatus antigen in patient sera by use of enzyme immunoassays: influence of different procedures of antigen immobilization. | igg and ige antibody titers against aspergillus fumigatus were measured in patient sera by enzyme immunoassays by use of antigens or allergens immobilized to different carriers. specific-igg antibodies were measured by a double antibody-layer enzyme immunoassay; specific ige was determined by phadezym -rast (pharmacia diagnostics). in both cases antigens and allergens were immobilized in two ways: first by covalent binding to cnbr-activated paper discs and second by spontaneous binding to polyst ... | 1984 | 6373891 |
| antigenic profile of some typical and septate phialide-strains of aspergillus fumigatus. | antigens from typical and septate phialide-strains of aspergillus fumigatus, a. fumigatus var. ellipticus, a. fischeri, a. flavus and a. niger were analysed by fused rocket and two-dimensional immunoelectrophoresis. depsite strain-to-strain variations, isolates of the two morphological forms of a. fumigatus showed a close similarity in their antigenic profile; the percentage of qualitative sharing ranged between 80% and 100%. the number of antigens shared by the isolates of a. fumigatus var. ell ... | 1984 | 6374936 |
| abnormal heterophils in a king shag with aspergillosis. | | 1984 | 6375104 |
| aspergillosis of the paranasal sinuses x-ray diagnosis, histopathology, and clinical aspects. | aspergillosis is not a rare disease of the paranasal sinuses; more than 80 cases were reported from 1976 to 1982 in the university ent clinic at graz, austria. of 59 patients studied, 27 presented almost metal-dense x-ray shadows resembling foreign bodies in one of the sinuses. by means of light and electron microscopic investigations as well as x-ray fluorescence analysis, it can be demonstrated that these areas are equivalent to local enrichment of calcium phosphate in the center of the noninv ... | 1984 | 6375518 |
| localized renal aspergillosis with hairy cell leukemia: a review of urinary tract aspergillosis in malignant and nonmalignant conditions. | a case of extensive unilateral renal aspergillosis in a man with hairy cell leukemia is described. this case report is unique because of the long duration of the infection that is more characteristic of patients without malignancy. the degree of unilateral renal involvement found, which included invasion of kidney parenchyma, is uncommon in patients with malignancy. such patients typically have diffuse disseminated disease with microabscesses. the literature on urinary tract aspergillosis in pat ... | 1984 | 6375823 |
| studies on wf-5239, a new potent platelet aggregation inhibitor. | wf-5239 was produced by a fungal strain identified as aspergillus fumigatus fresenius. the substance was purified by solvent extraction followed by chromatography on silica gel and then crystallized (c9h9no2, mp 142 approximately 145 degrees c). the chemical structure was determined from its physico-chemical properties as n-[2-cis(4-hydroxyphenyl)ethenyl]formamide. wf-5239 has inhibitory activity against rabbit platelet aggregation induced by arachidonic acid and collagen, with ic50 values of 1. ... | 1984 | 6376451 |
| surface antigens of intact aspergillus fumigatus mycelium: their localization using radiolabelled protein a as marker. | isotopically-labelled protein a from staphylococcus aureus was used as a marker to quantify binding of igg molecules to surface antigens of aspergillus fumigatus mycelium. the igg class antibodies were obtained from rabbits inoculated with mycelial fractions and from patients suffering from aspergillosis and aspergillus-related diseases. the highest incorporation of label was obtained with an antiserum from rabbits inoculated with a. fumigatus wall material. antibodies raised to other antigenic ... | 1984 | 6376701 |
| preparative isoelectric focusing of immunologically reactive components of aspergillus fumigatus mycelium. | a water-soluble mycelial extract of aspergillus fumigatus has been fractionated by preparative isoelectric focusing using carrier ampholytes in a layer of granulated gel. the separated components were located by staining paper prints from the gel. within a narrow ph range of 2.5 units, multiple protein bands were visualized with coomassie brilliant blue g. periodate-schiff-positive material was generally associated with the major protein zones. when these fractions were eluted the total recovery ... | 1984 | 6376702 |
| aspergillosis of the orbit. | | 1984 | 6376706 |
| electron microscopic examination of ribosome preparations from germinated spores of aspergillus fumigatus. | ribosomes were isolated from germinated spores (germlings) of aspergillus fumigatus and electron microscopy was used to determine qualitatively the extent of cellular contamination. after differential centrifugation, the initial crude preparation contained 80s ribosomes and numerous membrane contaminants in the form of membrane sheets, palisade aggregates, and vesicles 0.10-0.18 micron in size. gel filtration chromatography of crude ribosomes in sepharose cl-4b did not remove all of the membrane ... | 1984 | 6377081 |
| invasive aspergillosis in a "healthy" patient. | a case of invasive aspergillosis complicated by the formation of an aspergilloma is described. the patient, a 48-year-old man, was apparently healthy except for mild alcoholic steatosis of the liver. a review of the literature revealed that 5 of the 14 previously reported cases of invasive aspergillosis in seemingly immunocompetent hosts were associated with liver disease. immunologic investigation in this case revealed transient cutaneous anergy during the acute illness and normal lymphocyte fu ... | 1984 | 6378350 |
| [my toxin research]. | | 1984 | 6379220 |
| studies on the toxin of aspergillus fumigatus. xviii. photooxidation of asp-hemolysin in the presence of various dyes and its relation to the site of hemolytic activity. | the site of hemolytic activity of a toxin isolated from aspergillus fumigatus designated asp-hemolysin was determined by photooxidation techniques. the hemolytic activity of this toxin was strongly inhibited by photooxidation with methylene blue, rose bengal, riboflavin, or eosin g as a sensitizer, whereas crystal violet, hematoxylin, naphthol yellow s, bromothymol blue, methyl orange, and cresol red had no effect. ph dependence of the inactivation with methylene blue was observed in the narrow ... | 1984 | 6379381 |
| serological tests in the diagnosis of pulmonary aspergillosis. | sera from 44 patients with clinically suspected pulmonary aspergillosis (mainly of an allergic type) were examined for antibodies to aspergillus fumigatus using an enzyme-linked immunosorbent assay (elisa) and counter-immunoelectrophoresis (cie). of the sera, 15 were considered to contain aspergillus antibodies using elisa; 11 of these also contained precipitins by cie. in no instance was a cie-positive serum negative by elisa. the serum of 1 patient with autopsy-verified invasive pulmonary aspe ... | 1984 | 6379582 |
| evaluation of an enzyme-linked immunosorbent assay (elisa) for the diagnosis of aspergillus fumigatus intranasal infection of the dog. | elisa appears to be a less reliable method than counterimmunoelectrophoresis for the diagnosis of nasal aspergillosis in the dog. false-positive or false-negative results were recorded for anti-a. fumigatus igg in nine animals with aspergillosis and in 27 disease-free dogs although this problem could be reduced with careful selection of antigen. | 1984 | 6379918 |
| aspergillus fumigatus spore concentration in outside air: cardiff and st louis compared. | intermittent sampling of the atmosphere 3 days/week over a 12-month period using andersen samplers in cardiff, wales, u.k. and st louis, missouri, u.s.a., indicated average a. fumigatus spore concentrations of 13.5/m3 in st louis and 11.3/m3 in cardiff. both sites showed seasonal variations with highest concentrations during winter. | 1984 | 6380808 |
| [drug combinations in the treatment of invasive aspergillosis]. | | 1984 | 6381204 |
| invasive pulmonary aspergillosis after near-drowning. | after near-drowning following a car accident, a 27-year-old man developed severe ards. six days later aspergillus fumigatus was isolated in his sputum, and invasive pulmonary aspergillosis developed thereafter. aspergillus titre increased, and chest tomograms revealed cavities in both lungs. the treatment consisted essentially of amphotericin b and 5 fluorocytosine, intravenously and by inhalation, intensive postural drainage and mechanical ventilation with peep. after 41 days he was cured and d ... | 1984 | 6381566 |
| [pulmonary aspergillosis associated with endocarditis and cerebral embolism in a case of acute myeloblastic leukemia]. | | 1984 | 6381793 |
| relationship between skin tests and bronchial provocation tests with allergens found in organic dusts in patients with bronchial asthma. | a group of 153 patients with bronchial asthma were subjected to bronchial provocation and intracutaneous tests with allergen from the gram negative bacterium erwinia herbicola which commonly occurs in organic dusts. of this group, 80 persons were also examined with both tests with the allergen of aspergillus fumigatus and 96 persons with the house dust extract. the frequency of positive skin reactions to the tested allergens was much greater than that of the positive bronchial reactions. no sign ... | 1984 | 6382985 |
| use of aspergillus fumigatus culture filtrate fractions in elisa for the serological diagnosis of allergic aspergillosis. | | 1984 | 6384773 |
| association of aspergillus fumigatus with rhinitis. | | 1984 | 6385457 |
| in vivo bronchoalveolar macrophage defense against rhizopus oryzae and aspergillus fumigatus. | the ability of bronchoalveolar macrophages from normal, diabetic, and cortisone-treated mice to inhibit spore germination and kill fungal spores in vivo was investigated. the data indicated that the normal host controls different fungal infections in the lungs by different mechanisms. prevention of mucormycosis required inhibition of fungal spore germination by alveolar macrophages. in contrast, pulmonary defense against aspergillosis depended on early killing of conidia by alveolar macrophages ... | 1984 | 6387001 |
| microbial transformation of testosterone by aspergillus fumigatus. | microbial transformation has been employed for the preparation of the potentially important 15 beta-hydroxytestosterone which was obtained by fermentation of testosterone with a typical strain of aspergillus fumigatus. the metabolite was characterized by employing 1h and 13c nmr, mass spectrometry and i.r. analysis. high performance liquid chromatography (hplc) was used to examine the purity of the product and formation of other minor metabolites. | 1984 | 6387279 |
| [sphenoid sinusitis and panhypopituitarism]. | the case is reported of a patient who presented with panhypopituitarism simultaneously with sphenoid sinusitis due to aspergillus fumigatus. despite the absence of radiologically demonstrable suprasellar or intrasellar lesions, and without visible bone destruction, the authors conclude on the possibility of a pituitary lesion by contiguity. the pathogenic mechanisms are discussed. | 1984 | 6387901 |
| primary aspergillosis of the spine mimicking pott's paraplegia. | | 1984 | 6389555 |
| immunologic observations in sera of a patient with allergic bronchopulmonary aspergillosis by means of the enzyme-linked immunosorbent assay. | titers of igg, iga, and igm antibodies against aspergillus fumigatus were measured by elisa in sera of a patient with allergic bronchopulmonary aspergillosis during an acute stage, remission, and exacerbation of the disease. total ige, specific ige against a. fumigatus, and number of precipitation lines were also measured. elisa igg-, iga-, and igm-antibody titers were expressed in percentages of the titer of a strongly positive standard serum by use of the patient's own serum as a standard. the ... | 1984 | 6389649 |
| [clinical evaluation of 1% clotrimazole ointment in the treatment of corneal mycoses]. | | 1984 | 6389967 |
| management of pulmonary aspergilloma in the presence of active tuberculosis. | eleven cases of pulmonary aspergilloma complicating active cavitating pulmonary tuberculosis are reviewed. nine of the 10 patients who had combined medical (antituberculosis drugs) and surgical treatment were cured of their disease; one patient, who had bilateral multiple aspergillomas, died from massive haemoptysis after resection of one of the affected lobes. the only medically treated patient who refused surgery had fatal haemoptysis at home. pulmonary resection is recommended for patients wh ... | 1984 | 6390774 |
| [cerebral aspergillosis: presentation of a case]. | | 1983 | 6391387 |
| the prevalence of serum precipitating antibody to aspergillus fumigatus in adult cattle in britain. | the prevalence of precipitating antibody to a. fumigatus in 3509 sera from adult cattle in 44 herds was 25 per cent. only 19 per cent of sera from grazing or recently housed animals were positive compared with 30 per cent of those taken towards the end of the winter. mouldy hay was the most likely source of a. fumigatus antigens although a positive correlation between the prevalence of precipitins and either the mouldiness of the hay or the frequency of coughing in the springtime was not establi ... | 1984 | 6392358 |
| radioallergosorbent test (rast) for measurement of igg antibodies to aspergillus fumigatus in sera of patients with different lung diseases. | a radioallergosorbent test (rast) for measuring human anti-aspergillus fumigatus (af) antibodies of the igg class is described. the use of 125i-labelled animal antibodies against human igg is compared with the use of 125i-labelled protein a. under optimal conditions the radioactivity binding ratio between pooled patients' serum and pooled healthy persons' serum is 8-11.5. the immunoblotting technique was used to investigate so-called non-specific binding. the results obtained show that most if n ... | 1984 | 6392421 |
| analysis of aspergillus fumigatus germ tube surface structures by an immunofluorescent labelling technique. | | 1984 | 6392881 |
| fungal infection of the maxillary sinus. | | 1984 | 6395299 |
| antibody to aspergillus fumigatus antigens in normal sera: influence on positive-negative discrimination in elisa. | the response of precipitin-negative sera from non-selected asthmatic patients against a range of somatic and culture filtrate antigens of aspergillus fumigatus in elisa for anti-a. fumigatus igg is described. antibody to the various antigens was widely distributed but the precise distribution was dependent upon antigen type. to determine how the selection of negative reference sera from precipitin-negative sera can influence the discrimination between precipitin-positive and -negative sera in el ... | 1984 | 6397481 |
| serum iga antibodies to aspergillus fumigatus determined by enzyme-linked immunosorbent assay. | serum iga antibodies to three aspergillus fumigatus antigen fractions were determined by enzyme-linked immunosorbent assay (elisa) in 13 patients with aspergilloma, 23 patients with aspergillus lung infiltrates, 8 patients with allergic broncho-pulmonary aspergillosis (abpa), and 113 healthy blood donors. all three groups of patients had higher median serum iga antibody levels against the three antigen fractions than healthy subjects. thirty six (82%) of 44 patients had iga antibody values to at ... | 1984 | 6397961 |
| experimental aspergillosis in young chicks. | | 1984 | 6400351 |
| opportunistic esophagitis caused by aspergillus fumigatus. | the authors report on a 59-year-old man with opportunistic esophagitis caused by aspergillus fumigatus. although the patient had no underlying disease, esophagitis occurred after a short course of antibiotic therapy. a double contrast esophagogram showed multiple nodular or vertical plaque-like projections. endoscopy provided pathological conformation of aspergillus infection. | 1984 | 6400454 |
| [phytotoxic and antibiotic properties of gliocladium zaleskii pidopl. 11313 and chaetomium aureum chivers 8583]. | | 1984 | 6401099 |
| aspergillosis of the cerebral ventricles in a heroin abuser. case report and review of the literature. | aspergillosis of the cerebral ventricles developed in a 36-year-old heroin abuser who died during the sixth week of illness. the diagnosis was not made during life. a review of our case and of four previous cases from the literature indicates that aspergillosis should be considered in parenteral drug abusers with the syndrome of chronic meningitis or ventriculitis. the diagnosis is difficult to establish, but serologic tests may be helpful. this form of cns aspergillosis can be cured with antifu ... | 1983 | 6401419 |
| computer-assisted rapid enzyme-linked immunosorbent assay (elisa) in the serological diagnosis of aspergillosis. | a computer-assisted method for the positive/negative discrimination of elisa data is described. this method was applied to a rapid elisa procedure for igg class antibodies to aspergillus fumigatus in which the performance time of the test was reduced to 1 h. the method gives results which compare well with those by agar gel double diffusion (agdd). the computer-assisted reading, calculation and tabulation of elisa results from one microtitre plate is performed in less than 2 min and permits anal ... | 1983 | 6402546 |
| persistent dyspnea in a man with cystic fibrosis. | | 1983 | 6404806 |
| efficacy of enzyme-linked immunosorbent assay in serodiagnosis of aspergillosis. | sera from 43 cases of aspergillosis, 73 cases of other bronchopulmonary diseases, and 50 healthy persons were examined for the presence of antibodies to aspergillus fumigatus. enzyme-linked immunosorbent assay proved to be more efficacious than the immunodiffusion test and counterimmunoelectrophoresis in the cases of allergic bronchopulmonary and invasive aspergillosis. | 1983 | 6406541 |
| exoantigen tests for the immunoidentification of fungal cultures. | exoantigen tests for the immunoidentification of fungal pathogens are playing a new and significant role in the diagnostic laboratory. properly performed and controlled exoantigen tests lead to rapid, accurate identification of cultures of many fungal pathogens. the tests are particularly valuable in identifying dimorphic pathogens that are difficult to convert or with atypical cultures. we review the value of exoantigen tests for identifying mycelial form fungi: aspergillus spp. blastomyces der ... | 1983 | 6410243 |
| "haysickness" in icelandic horses: precipitin tests and other studies. | blood samples were taken from 18 healthy horses (group a), 15 horses clinically diagnosed to have "haysickness" ("farmer's lung") (group b), 10 closely related horses (group c) and 14 inbred horses (group d). precipitins in sera were measured by double gel diffusion test against micropolyspora faeni, thermoactinomyces vulgaris, aspergillus fumigatus, alternaria, penicillium and rhizopus species. in group a, all the horses were precipitin negative except one with a faint reaction to rhizopus spec ... | 1983 | 6411460 |
| comparison of antibody measurements against aspergillus fumigatus by means of double-diffusion and enzyme-linked immunosorbent assay (elisa). | igg antibody titers against aspergillus fumigatus from different sera were measured by means of a standardized elisa and compared with precipitates measured by double diffusion (d.d.). there was a significant correlation between the number of precipitates and the elisa igg titers in the 758 sera examined. however, in several individual sera within this group, large deviations between these two immunologic parameters were found. further analysis indicated that elisa detects antibodies against non ... | 1983 | 6411795 |
| [aspergillus infection of severe burns]. | aspergillus, which has a saprophytic life, is an opportunistic fungus and manifests his pathogenicity when a weakened state of the host facilitates its development. the conditions are particularly favorable in severely burned patients like the 54-year-old woman presented here. the criteria of pathogenicity of this opportunistic fungus, the incidence of epidemiology and prognosis of this type of infection and the clinical signs that allow an early diagnosis are discussed here. | 1983 | 6414854 |
| [aspergillus mycosis of the paranasal sinuses. roentgen diagnosis, clinical course and histopathology]. | | 1983 | 6415447 |
| aspergillus endophthalmitis in an intravenous drug user. | a 27-year-old male drug user administered methamphetamine hydrochloride solution intravenously (iv) from a storage vial. within two weeks he was admitted with a fungal endophthalmitis of the right eye. a diagnostic and therapeutic vitrectomy was performed. aspergillus fumigatus was cultured from the drug storage vial and the vitreous biopsy specimen. the endophthalmitis was not controlled by iv and intravitreal amphotericin b. pathological examination revealed fungal abscesses in the vitreous an ... | 1983 | 6418052 |
| rapid hematogenous dissemination of aspergillus fumigatus and a. flavus spores in turkey poults following aerosol exposure. | cultures of blood samples taken from 3-week-old turkey poults exposed to aerosolized spores of either aspergillus fumigatus or a. flavus for 15 min yielded organisms. aspergillus fumigatus was also isolated from brain and liver tissue samples taken immediately after exposure. exfoliated cells from the lungs of 10 poults exposed to aerosolized spores of a. fumigatus were allowed to attach to glass slides in tissue culture. several types of the fixed and stained cells had attached or ingested spor ... | 1983 | 6418131 |
| fractionation of aspergillus fumigatus antigens by hydrophobic interaction chromatography and gel filtration. | aspergillus fumigatus somatic antigen prepared from young hyphae was fractionated by hydrophobic interaction chromatography followed by gel filtration. the antigenic activity of fractions was investigated by enzyme-linked immunosorbent assay, crossed immunoelectrophoresis, and immunodiffusion. by enzyme-linked immunosorbent assay, high levels of igg antibodies were detected against an antigen fraction of approximate molecular weight 470,000 both in patients with aspergillosis (n = 3) and in heal ... | 1984 | 6421747 |
| comparison of antigens and serological methods in aspergillus fumigatus antibody detection. | | 1984 | 6422293 |
| functional studies on mouse macrophages activated by phospholipids from listeria monocytogenes and aspergillus fumigatus. | the administration of phospholipids from listeria monocytogenes and aspergillus fumigatus to mice resulted in the development of macrophages with increased functional activity. it has been found that stimulated macrophages have increased phagocytic activity, enhanced chemotactic reactivity and augmented adherence to plastic surface. the activity of fcig macrophages and complement receptors as well as the rate of the recovery of the fcig receptors after phagocytosis were significantly higher in a ... | 1983 | 6422902 |
| clinical-immunologic correlates: a differential diagnostic update. allergic bronchopulmonary aspergillosis. | | 1984 | 6423615 |
| the allergenic and antigenic properties of spore extracts of aspergillus fumigatus: a comparative study of spore extracts with mycelium and culture filtrate extracts. | the antigenic properties of conidial preparations of aspergillus fumigatus were compared with mycelial and culture filtrate extracts by use of sera of patients with aspergillosis and hyperimmune rabbit serum. biologic activities were tested by intracutaneous tests. the immunologic parameters used were: precipitating properties in double-diffusion, igg binding by elisa, ige binding by enzyme inhibition assay, and by enzyme allergosorbent test. it has been demonstrated that the components that are ... | 1984 | 6425387 |
| primary mycotic infection of paranasal sinuses. | eight cases of primary mycotic infection of paranasal sinuses with aspergillus and candida species encountered during july, 1979 to december 1981 are being presented. their clinical, mycological and serological responses have been discussed. aspergillus flavus was isolated from all the seven cases with aspergillosis and candida albicans, along with c. tropicalis, was isolated from one case. | 1984 | 6425695 |
| serum ige as an important aid in management of allergic bronchopulmonary aspergillosis. | differentiating patients with allergic bronchopulmonary aspergillosis (abpa) from patients with asthma who have immediate skin reactivity to aspergillus fumigatus may be difficult when the characteristic clinical and laboratory findings of abpa are absent. this article describes the response of abpa patients to corticosteroid therapy. after treatment of the acute stage of the disease with corticosteroid therapy, all abpa patients had greater than or equal to 35% reduction of the total serum ige ... | 1984 | 6429230 |
| [mass occurrence of mycotic tracheitis in chickens]. | an enzootic of chick mycosis, caused by the spores of the fungus aspergillus fumigatus, is described. the mycotic infection affected the respiratory tract of the birds; pathological changes were located mainly in the region of the trachea. the changes had the nature of diphtheroid necrotic inflammation destroying the mucous membrane and causing almost an obstruction of the trachea. deposits of granulomatous inflammation, containing fungus elements, were detected in the peritracheal tissue, and i ... | 1984 | 6431681 |
| [hospital aspergillosis]. | | 1984 | 6431721 |
| influence of phospholipids from listeria monocytogenes and aspergillus fumigatus on the bactericidal and fungicidal activity of mouse peritoneal macrophages. | investigations were carried out on an influence of phospholipids from a. fumigatus and l. monocytogenes on the bactericidal and fungicidal activity of mouse peritoneal macrophages. l. monocytogenes bacilli and c. neoformans fungi served as the experimental microorganisms. phospholipids from a. fumigatus and l. monocytogenes were shown to significantly increase macrophage activity under in vivo and in vitro conditions. this was accompanied by an intensified bactericidal and fungicidal activity of ... | 1984 | 6433852 |
| recent studies on aspergillosis in turkey poults. | a review of the studies on aspergillosis in turkey poults at the national animal disease center include limited field studies, pathogenicity studies, and vaccine development. natural ventilation in turkey rearing houses was effective in reducing airborne propagules of four major fungal genera, but the effectiveness of ventilation appeared to be limited by the width of the building. aspergillus fumigatus was more effective than a. flavus in producing mortalities in aerosol exposed poults. toxigen ... | 1984 | 6436708 |
| allergic bronchopulmonary aspergillosis. | | 1984 | 6438210 |
| immunohistochemical identification of aspergillus fumigatus in farmer's lung. | fragments of fungi in a granuloma were demonstrated in lung biopsy specimens of two patients with farmer's lung by using an avidin-biotin-complex method with non-conjugated rabbit antiserum to aspergillus fumigatus. our findings suggest that the type iv or cell-mediated immunity at least partly explains the pathogenesis of farmer's lung. | 1984 | 6441428 |
| [otomycosis: etiology and analysis of predisposing factors]. | an otomycosis was found in 80 cases of external otitis on a total of 132. itching was the characteristic beginning, rapidly followed by pain, conductive hearing loss, tympanic perforation. aspergillus was isolated in 81.7% of cases: in particular, a. niger in 67.1% of cases. a. flavus in 13.4% a. fumigatus in 1.2%. candida albicans was isolated in 11% of cases. a statistical analysis based on chi 2 test was performed to evaluate the role of possible predisposing factors. highly significant facto ... | 1984 | 6442867 |
| analysis of antibodies to aspergillus fumigatus antigens by class-specific enzyme-linked immunosorbent assay in patients with pulmonary aspergillosis. | | 1984 | 6443202 |
| relationship between the house dust and mite allergen by immunochemical and clinical evidence. | this investigation was carried out to determine antigenic potency in extracts of house dust, d. pteronyssinus and d. farinae and aspergillus fumigatus with observation of precipiting antibodies in the serum of immunised rabbits. the titre of precipiting antibodies dependens on the mode of immunisation, preparation and concentration of antigens. our investigations revealed that the house dust antigen comprises antigen of d. pteronyssinus, which can clarify the cross-reaction between the antiserum ... | 1980 | 6447446 |
| degradation of humic acids, extracted from manure and soil by some streptomycetes and fungi. | humate-decomposing microorganisms were isolated from alluvial soil, farmyard manure and peat by direct plating and enrichment techniques. peat was found to harbour more of these organisms than soil and manure. out of 21 actinomycetes and 6 fungi 9 and 3 isolates, respectively, were found to utilize manure-humate as a sole source of carbon and to a less extent as a source of both carbon and nitrogen in liquid medium. these efficient cultures were identified as streptomyces spec. (a 11 and a 12). ... | 1980 | 6448526 |
| evolutionary origins of vertebrate hormones: substances similar to mammalian insulins are native to unicellular eukaryotes. | tetrahymena pyriformis, neurospora crassa, and aspergillus fumigatus that had been grown in simple defined media were extracted with acid ethanol by a classic method for recovering insulin from pancreas. after filtration of the extracts on sephadex g-50, distinct peaks of insulin immunoreactivity were recovered in the region typical of insulin. the gel-filtered material from the tetrahymena had reactivity in the pork insulin radioimmunoassay about equal to its reactivity in the insulin bioassay ... | 1980 | 6449704 |
| association of aspergillus fumigatus with sugar-cane bagasse. iii. immunological studies. | in view of the epidemiological significance of aspergillus fumigatus in allergic bronchopulmonary aspergillosis (abpa) and its abundance in sugar-cane bagasse the antigenic properties of 11 strains isolated from bagasse have been studied. three strains isolated from other sources were also included in the study. for comparison sake, a. fumigatus var. ellipticus and a. viridi-mutans were also studied. all the strains of a. fumigatus irrespective of the source of isolation were found to be immunol ... | 1981 | 6460397 |
| neutrophil chemotactic activity released in supernatants of human leukocytes challenged with antigens or anti-human ige. | neutrophil chemotactic activity was released into the supernatants of leukocytes from atopic individuals challenged with rabbit anti-human ige, ragweed, or aspergillus fumigatus antigen and from nonatopic individuals only on challenge with anti-ige. using a recently reported procedure for removing ige from basophil receptors, it was possible to passively sensitize leukocytes from nonatopic individuals with plasma from atopic donors and to convert nonreleaser cells to cells releasing neutrophil c ... | 1984 | 6470565 |
| the primary structure of the cytotoxin restrictocin. | the complete amino acid sequence of the single polypeptide chain of cytotoxin restrictocin has been determined. its structure was established by automated edman degradation of the intact molecule reduced and [14c]carboxymethylated and of fragments obtained by chemical cleavage of the protein with cyanogen bromide and bnps-skatole and by enzymatic cleavage of the polypeptide chain with trypsin. the molecule consists of 149 amino acid residues with a calculated relative molecular mass of 16836. th ... | 1984 | 6479166 |
| evaluation of an indirect hemagglutination inhibition technique for identifying antibody in animals experimentally and naturally exposed to fungi. | rabbits were exposed to aerosols containing spores of aspergillus fumigatus, aspergillus flavus, aspergillus niger, or of a penicillium sp. sera from these rabbits were tested by indirect hemagglutination (iha) and by iha inhibition. the serologic reactions with the rabbit sera were compared to reactions with sera from cattle naturally exposed to airborne microorganisms. by three months of age, most cattle had positive iha reactions to a. fumigatus and penicillium antigens. the iha inhibition te ... | 1984 | 6493314 |
| fungal sinusitis in healthy and immunocompromised individuals. | clinical and microbiologic aspects of fungal sinusitis occurring in six patients are presented. three of the six patients were immunosuppressed. fatal disseminated fungal disease developed in two of those immunosuppressed. the three patients with normal immune function had fungal infections confined to the nasal sinuses. aspergillus fumigatus and aspergillus flavus were recovered from the immunosuppressed patients and sporothrix schenckii, alternaria species, and pseudallescheria boydii were rec ... | 1984 | 6496403 |
| hypersensitivity pneumonitis concomitant with acute airway obstruction after exposure to hay dust. | the case of a non-atopic farmer who had developed severe respiratory as well as systemic symptoms upon exposure to hay dust during the past several years is presented. inhalation challenge by his own hay induced an unusual association of peripheral and central airway obstruction beginning immediately, and hardly susceptible to therapeutic control, as well as the typical hypersensitivity pneumonitis reaction several hours later. by means of double immunodiffusion it was possible to demonstrate se ... | 1984 | 6522842 |
| enhancement of the in vitro activity of amphotericin b against aspergillus spp. by tetracycline analogs. | strains of aspergillus fumigatus, aspergillus flavus, and aspergillus niger were tested for in vitro susceptibility to amphotericin b alone and in combination with fixed concentrations of tetracycline, doxycycline, or minocycline, using buffered minimal essential medium in microtiter plates. enhanced inhibitory activity was seen, especially with combinations of amphotericin b and minocycline. synergistic activity between amphotericin b and minocycline was observed in each of five isolates of eac ... | 1984 | 6524900 |
| serum ige and ige antibody levels in patients with bronchial asthma, atopic dermatitis, eosinophilic granulomas of the soft tissue (kimura's disease) and other diseases. | hyper-ige immunoglobulinemia was observed in bronchial asthma, atopic dermatitis, eosinophilic granuloma of the soft tissue (kimura's disease), disseminated visceral eosinophilic granulomas (zuelzer-apt syndrome) and disseminated eosinophilic collagen disease, ige antibodies to environmental allergens (dermatophagoides farinae mites, aspergillus fumigatus, mountain cedar pollen, and candida albicans) were found in bronchial asthma, atopic dermatitis and combinations of the two, but were not sign ... | 1983 | 6600385 |
| allergic bronchopulmonary aspergillosis: reactivity of ige and igg antibodies with antigenic components of aspergillus fumigatus (ige/igg antigen complexes). | sera of patients with abpa were tested by xrie tests incorporating their own serum (self-xrie) to detect the presence of igg/ige antigen complexes to a "reference" aspergillus fumigatus preparation. of the 32 sera studied, 29 (90%) had visible precipitin (igg) peaks, and 27 of these 29 as well as the three apparently precipitin-negative sera, i.e., 30 (94%), showed binding of specific ige by autoradiography. the two precipitin-positive sera that did not show ige binding were also skin test negat ... | 1983 | 6605984 |
| airborne bacteria, endotoxin and fungi in dust in poultry and swine confinement buildings. | airborne dust in swine and poultry confinements was analyzed to determine concentrations of total and gram-negative bacteria, total fungi, aspergillus fumigatus and endotoxin. airborne concentrations of total and gram-negative bacteria in swine and confinement units have been found to be as high as, or higher, than those found in other environments, such as wastewater treatment plants and cotton card rooms, where microbiologically contaminated organic dusts were present. airborne endotoxin conce ... | 1983 | 6613856 |
| superinfections in herpes simplex keratitis. | we reviewed 15 cases of culture-proven corneal superinfections in 15 patients (eight men and seven women ranging in age from 41 to 86 years) with recurrent herpes simplex keratitis. the factors that appeared to increase the risk of superinfection were the presence of an epithelial defect (found in all 15 cases), a history of recurrent herpetic keratouveitis (found in ten cases), and the use of topical corticosteroids (found in 13 cases). eight of the 15 patients were taking antibiotics at the ti ... | 1983 | 6614114 |
| the diagnostic approach to immediate hypersensitivity in patients with allergic rhinitis; a comparison of nasal challenges and serum rast. | nasal challenges performed in 182 patients with allergic rhinitis revealed 273 positive and 125 negative responses to house dust, grass pollen, cat and dog danders and aspergillus fumigatus, which all correlated with disease history and intracutaneous tests. in these randomly selected patients the specific ige antibodies in the serum to the same allergens as those used for nasal challenges were determined quantitatively by serum rast. additionally, blood and nasal eosinophilia were recorded duri ... | 1983 | 6614602 |
| minimal inhibitory concentrations of lucknomycin, a new polyenic derivative, for candida and aspergillus spp. | the minimal inhibitory concentrations (mics) of lucknomycin, a new polyenic derivative, were determined for 101 clinical isolates of candida, 38 clinical or environmental strains of aspergillus fumigatus, and 30 isolates of a. niger. the most susceptible species were candida albicans and candida tropicalis (mean mic, 0.4 micrograms/ml). aspergillus spp. were less susceptible, with mean mics of 0.60 micrograms/ml for aspergillus niger and 9.2 micrograms/ml for aspergillus fumigatus. | 1983 | 6625552 |
| total serum ige levels in venezuelan schoolchildren. | seventy-eight disease-free children were evaluated by prist for total serum ige in order to establish the normal range for this immunoglobulin and assess its utility, in tropical climates, such as venezuela, as a diagnostic tool for clinical allergy. seventy-eight normals were selected from a group of 1053 children, aged 7-12 years from fourteen schools in caracas. exclusion from the normal pool was based on nationality, and on historical, clinical, and/or laboratory evidence of atopic and/or in ... | 1983 | 6640887 |
| killing of aspergillus spores depends on the anatomical source of the macrophage. | to resolve the controversy over the capacity of macrophages to kill or inhibit germination of aspergillus spores, we compared this function in peritoneal and alveolar macrophages. alveolar macrophages from rabbits killed 82 to 90% and completely digested 72 to 82% of spores of aspergillus fumigatus in 30 h. in contrast, peritoneal macrophages could not even inhibit the germination of ingested spores; more than 85% transformed into mycelia within 24 h. killing by alveolar macrophages was delayed ... | 1983 | 6642661 |
| pulmonary fibrosis, with sarcoid granulomas and angiitis, associated with handling of mouldy lichen. | we report a case of extrinsic allergic bronchiolo-alveolitis associated with handling of mouldy lichen. the patient had periodic dyspnoea, cough and mucoid sputum, and a micronodular infiltration of both lungs with slight restrictive ventilatory insufficiency. an open lung biopsy showed interstitial inflammation and fibrosis with sarcoid granulomas and angiitis. the symptoms disappeared during long term corticosteroid therapy, but reappeared every year when the patient participated in the handli ... | 1983 | 6653692 |
| intrinsic polymorphonuclear chemotactic defect in a boy with chronic granulomatous disease. | a six year old boy is described who suffured from recurrent and protracted infections of multiple organs by various catalase positive bacteria. a severe episode of osteomyelitis involving several bones was caused by aspergillus fumigatus. studies of his pmns revealed impaired metabolic as well as microbicidal functions characteristic of cgd. chemiluminescence in response to both opsonized zymosan and sodium fluoride was markedly depressed, while control pmns showed significant responses. control ... | 1983 | 6670661 |
| in vitro activities of two new antifungal azoles. | the antifungal activities of equimolar quantities of three azole compounds, bay n 7133 [1-(4-chlorophenoxy)-3,3-dimethyl-2-(1,2,4-triazole-1-yl)methylbutan-2-o1], bay 1 19139 [1-(4-chlorophenoxy)-1-(1-imidazolyl)-3,3-dimethyl-2-butanol hydrochloride], and ketoconazole, were compared by testing the susceptibility in vitro of 10 clinical isolates each of candida albicans, candida parapsilosis, torulopsis glabrata, cryptococcus neoformans, aspergillus fumigatus, aspergillus niger, aspergillus flavu ... | 1984 | 6721465 |
| specific susceptibility to mucormycosis in murine diabetes and bronchoalveolar macrophage defense against rhizopus. | to assess the influence of diabetes mellitus in predisposing to pulmonary mucormycosis, a murine model of streptozotocin-induced diabetes was used. intranasal inoculation of rhizopus oryzae into diabetic mice resulted in mucormycotic infection with histopathology resembling pulmonary mucormycosis observed in humans. there was no mortality nor infection in inoculated normal mice. diabetic mice had fatal infections caused by r. oryzae but significantly reduced mortality following inoculation with ... | 1984 | 6736246 |
| successful treatment of pulmonary and cerebral aspergillosis in an immunosuppressed child. | a favourable outcome was observed in a 12 year-old boy who developed invasive pulmonary and cerebral aspergillosis during antineoplastic treatment for central nervous system relapse of acute lymphoblastic leukemia. combination therapy with amphotericin b and 5-fluorocytosine led to complete regression of pulmonary infiltrates. despite enlargement of the cerebral lesion monitored by computerized tomography, no viable fungi were found in the completely resected abscess after a 4 weeks' course of a ... | 1982 | 6749508 |
| [pulmonary aspergillomas in tuberculous caverns]. | | 1982 | 6750707 |
| studies on aspergillus fumigatus from the human lungs. | on the basis of cultural, morphological and developmental studies of the two aspergillus isolates from the lungs of an aspergillosis patient, the taxonomic status of aspergillus phialiseptus is discussed. the elimination of the name a. phialiseptus is proposed as the isolates were found by the authors to belong to a. fumigatus. | 1982 | 6750981 |
| extracellular proteolytic activity of aspergillus fumigatus strains with septum-like structures in their phialides in serum-albumin agar--preliminary report. | | 1982 | 6750988 |
| nosocomial aspergillosis: a retrospective review of airborne disease secondary to road construction and contaminated air conditioners. | a retrospective review of autopsy records was performed to evaluate a clustering of patients shown to have invasive pulmonary aspergillosis during the period july 1, 1978 through october 31, 1980 at milwaukee county medical center, milwaukee, wisconsin. during this period, ten patients, all of whom were immunosuppressed by either hematologic malignancy (two), advanced age (one), or iatrogenically to prevent rejection of renal allografts (seven) were found to have invasive pulmonary aspergillosis ... | 1982 | 6751070 |
| allergic bronchopulmonary aspergillosis in children. | | 1982 | 6752013 |
| metabolism of progesterone by aspergillus fumigatus. | | 1982 | 6752584 |
| asbestos exposure and aspergillus infection. | four cases of asbestos-related changes of the lung complicated by aspergillus infection are described. in such cases, the resulting clinical and radiological picture can give rise to some confusion. it is suggested that exposure to asbestos leads to changes in the bronchi and the lung parenchyma which can facilitate growth of the fungus. it is also possible that asbestos can affect the immune system in such a way that the body's anti-fungal defences are weakened. the aspergillus infection can mi ... | 1982 | 6754414 |
| [comparative study of fungicidal activity in vitro of various quaternary ammonium compounds used in ophthalmology]. | a study was conducted to evaluate the antifungal activity in vitro of 5 quaternary ammonium compounds. n cetylpyridinium was found to be particularly active against candida albicans and aspergillus fumigatus. the association of n cetylpyridinium and of neosynephrine, found in various eye drop compositions, resulted in potentation of the antifungal activity of this quaternary ammonium. | 1982 | 6754796 |
| aspergillus spinal epidural abscess. | | 1982 | 6754984 |